Mitochondrial PKCε and mitochondrial ATP-sensitive K+ channel copurify and coreconstitute to form a functioning signaling module in proteoliposomes

Circulation Research

Volumn 99, Issue 8, 2006, Pages 878-883

  Jabůrek, Martin ^a,b   Costa, Alexandre D T ^a   Burton, Jana R ^a   Costa, Cinthia L ^a   Garlid, Keith D ^a  

^a PORTLAND STATE UNIVERSITY   (United States)

^b INSTITUTE OF PHYSIOLOGY   (Czech Republic)

Author keywords

ATP sensitive K+ channel; Cardioprotection; Mitochondria; Protein kinase C ; Protein phosphatase; Reactive oxygen species; Reconstitution

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CHELERYTHRINE; DETERGENT; ENZYME INHIBITOR; EPSILON GLUTAMYLALANYLVALYLSERYLLEUCYLLYSYLPROLYLTHREONINE; HYDROGEN PEROXIDE; PEPTIDE DERIVATIVE; PHORBOL 12 ACETATE 13 MYRISTATE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE C ACTIVATOR; PROTEIN KINASE C EPSILON; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; PHOSPHOPROTEIN PHOSPHATASE; POTASSIUM; POTASSIUM CHANNEL; PROTEOLIPID; PROTEOLIPOSOMES;

ANIMAL CELL; ARTICLE; ENZYME ACTIVITY; ENZYME PURIFICATION; EXTRACTION; HEART PROTECTION; IMMUNOBLOTTING; ION EXCHANGE CHROMATOGRAPHY; LIPID VESICLE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEOLIPOSOME; RAT; SIGNAL TRANSDUCTION; ANIMAL; CHEMISTRY; ENZYME ACTIVATION; ENZYMOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MITOCHONDRIAL MEMBRANE; PHYSIOLOGY;

ADENOSINE TRIPHOSPHATE; ANIMALS; ENZYME ACTIVATION; MITOCHONDRIAL MEMBRANES; PHOSPHOPROTEIN PHOSPHATASE; POTASSIUM; POTASSIUM CHANNELS; PROTEIN KINASE C-EPSILON; PROTEOLIPIDS; RATS; RESEARCH SUPPORT, N.I.H., EXTRAMURAL; RESEARCH SUPPORT, NON-U.S. GOV'T; SIGNAL TRANSDUCTION;

EID: 33749670149     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000245106.80628.d3     Document Type: Article

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