Acetylcholine leads to free radical production dependent on KATP channels, Gi proteins, phosphatidylinositol 3-kinase and tyrosine kinase

Cardiovascular Research

Volumn 55, Issue 3, 2002, Pages 544-552

  Oldenburg, Olaf ^a   Qin, Qining ^a   Sharma, Ana R ^a   Cohen, Michael V ^a   Downey, James M ^a   Benoit, Joseph N ^a  

^a UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Acetylcholine; Free radicals; K ATP channel; Mitochondria; Preconditioning; Protein kinases; Signal transduction

Indexed keywords

4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; ACETYLCHOLINE; ATROPINE; CELL MARKER; DIAZOXIDE; FREE RADICAL; GENISTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; IONOPHORE; MUSCARINIC RECEPTOR BLOCKING AGENT; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SCAVENGER; TIOPRONIN; VALINOMYCIN; WORTMANNIN; 4 DIPHENYLACETOXY 1,1 DIMETHYLPIPERIDINIUM; 4-DIPHENYLACETOXY-1,1-DIMETHYLPIPERIDINIUM; 5 HYDROXYDECANOIC ACID; 5-HYDROXYDECANOIC ACID; ANDROSTANE DERIVATIVE; CHOLINERGIC RECEPTOR; DECANOIC ACID DERIVATIVE; ENZYME INHIBITOR; HYDROXYACID; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; METHACHOLINE CHLORIDE; MUSCARINIC AGENT; PIPERIDINE DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; FLUORESCENCE; HEART MITOCHONDRION; MALE; NONHUMAN; POTASSIUM TRANSPORT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RABBIT; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ANALYSIS OF VARIANCE; ANIMAL; AORTA; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; FLUORESCENCE MICROSCOPY; ISCHEMIC PRECONDITIONING; METABOLISM; METHODOLOGY; PERFUSION; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACETYLCHOLINE; ANALYSIS OF VARIANCE; ANDROSTADIENES; ANIMAL; AORTA; ATROPINE; CELL LINE; DECANOIC ACIDS; DIAZOXIDE; ENZYME INHIBITORS; FEMALE; FREE RADICAL SCAVENGERS; G-PROTEIN, INHIBITORY GI; GENISTEIN; HYDROXY ACIDS; IONOPHORES; ISCHEMIC PRECONDITIONING; MALE; MERCAPTOPROPIONYLGLYCINE; METHACHOLINE CHLORIDE; MICROSCOPY, FLUORESCENCE; MUSCARINIC AGONISTS; MUSCLE, SMOOTH, VASCULAR; PERFUSION; PERTUSSIS TOXIN; PIPERIDINES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; PROTEIN-TYROSINE KINASE; RABBITS; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, CHOLINERGIC; SIGNAL TRANSDUCTION; VALINOMYCIN; ANIMALS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; PROTEIN-TYROSINE KINASES; THIOPRONINE;

EID: 0036023627     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(02)00332-2     Document Type: Article

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