Opioid-Induced Cardioprotection Occurs via Glycogen Synthase Kinase β Inhibition during Reperfusion in Intact Rat Hearts

Circulation Research

Volumn 94, Issue 7, 2004, Pages 960-966

  Gross, Eric R ^a   Hsu, Anna K ^a   Gross, Garrett J ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Glycogen synthase kinase; Opioids; Phosphatidylinositol 3 kinase; Reperfusion; Target of rapamycin

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 HYDROXYBENZYL] N,N DIETHYLBENZAMIDE; DELTA OPIATE RECEPTOR AGONIST; ENZYME INHIBITOR; GLYCOGEN SYNTHASE KINASE; GLYCOGEN SYNTHASE KINASE BETA; GLYCOGEN SYNTHASE KINASE INHIBITOR; MORPHINE; OPIATE; OPIATE AGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; SERINE; TARGET OF RAPAMYCIN KINASE; TYROSINE; UNCLASSIFIED DRUG; WORTMANNIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; HEART INFARCTION PREVENTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINOPHENOLS; ANDROSTADIENES; ANIMALS; BENZAMIDES; CARDIOTONIC AGENTS; CHROMONES; GLYCOGEN SYNTHASE KINASE 3; INDOLES; MALE; MALEIMIDES; MORPHINE; MORPHOLINES; MYOCARDIAL INFARCTION; NARCOTIC ANTAGONISTS; PIPERAZINES; PREMEDICATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, DELTA; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; SIGNAL TRANSDUCTION; SIROLIMUS;

EID: 1842841258     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000122392.33172.09     Document Type: Article

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