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Volumn 106, Issue 3, 2011, Pages 355-369

STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart

Author keywords

Anoxia reoxygenation; Embryonic heart; JAK2 STAT3 pathway; Oxyradicals; RISK pathway

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; DNA; GLYCOGEN SYNTHASE KINASE 3BETA; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 ALPHA PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 79955538001     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-011-0152-5     Document Type: Article
Times cited : (21)

References (56)
  • 1
    • 27744460150 scopus 로고    scopus 로고
    • JAK-STAT pathway in cardiac ischemic stress
    • DOI 10.1016/j.vph.2005.08.020, PII S1537189105001898, JAK/STAT Signaling Pathway and the Vasculature
    • R Ananthakrishnan K Hallam Q Li R Ramasamy 2005 JAK-STAT pathway in cardiac ischemic stress Vascul Pharmacol 43 353 356 10.1016/j.vph.2005.08.020 16260187 10.1016/j.vph.2005.08.020 1:CAS:528:DC%2BD2MXht1ars73O (Pubitemid 41608759)
    • (2005) Vascular Pharmacology , vol.43 , Issue.5 , pp. 353-356
    • Ananthakrishnan, R.1    Hallam, K.2    Li, Q.3    Ramasamy, R.4
  • 2
    • 79551679145 scopus 로고    scopus 로고
    • Mitochondria in postconditioning
    • 2010 Sep 29. [epub ahead of print] doi: 10.1089/ars.2010.3309
    • Boengler K, Heusch G, Schulz R (2010) Mitochondria in postconditioning. Antioxid Redox Signal 2010 Sep 29. [epub ahead of print] doi: 10.1089/ars.2010.3309
    • (2010) Antioxid Redox Signal
    • Boengler, K.1    Heusch, G.2    Schulz, R.3
  • 3
    • 53749100817 scopus 로고    scopus 로고
    • The myocardial JAK/STAT pathway: From protection to failure
    • 10.1016/j.pharmthera.2008.08.002 18786563 10.1016/j.pharmthera.2008.08. 002 1:CAS:528:DC%2BD1cXht1Knsb3J
    • K Boengler D Hilfiker-Kleiner H Drexler G Heusch R Schulz 2008 The myocardial JAK/STAT pathway: from protection to failure Pharmacol Ther 120 172 185 10.1016/j.pharmthera.2008.08.002 18786563 10.1016/j.pharmthera.2008.08.002 1:CAS:528:DC%2BD1cXht1Knsb3J
    • (2008) Pharmacol Ther , vol.120 , pp. 172-185
    • Boengler, K.1    Hilfiker-Kleiner, D.2    Drexler, H.3    Heusch, G.4    Schulz, R.5
  • 4
    • 78649324875 scopus 로고    scopus 로고
    • Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion
    • 10.1007/s00395-010-0124-1 20960209 10.1007/s00395-010-0124-1 1:CAS:528:DC%2BC3cXhtlClu7bP
    • K Boengler D Hilfiker-Kleiner G Heusch R Schulz 2010 Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion Basic Res Cardiol 105 771 785 10.1007/s00395-010-0124-1 20960209 10.1007/s00395-010-0124-1 1:CAS:528:DC%2BC3cXhtlClu7bP
    • (2010) Basic Res Cardiol , vol.105 , pp. 771-785
    • Boengler, K.1    Hilfiker-Kleiner, D.2    Heusch, G.3    Schulz, R.4
  • 5
    • 0037315554 scopus 로고    scopus 로고
    • Role of the JAK-STAT pathway in protection against myocardial ischemia/reperfusion injury
    • DOI 10.1016/S1050-1738(02)00230-X, PII S105017380200230X
    • R Bolli B Dawn YT Xuan 2003 Role of the JAK-STAT pathway in protection against myocardial ischemia/reperfusion injury Trends Cardiovasc Med 13 72 79 S105017380200230X 12586443 10.1016/S1050-1738(02)00230-X 1:CAS:528: DC%2BD3sXhtVClurY%3D (Pubitemid 36175531)
    • (2003) Trends in Cardiovascular Medicine , vol.13 , Issue.2 , pp. 72-79
    • Bolli, R.1    Dawn, B.2    Xuan, Y.-T.3
  • 6
    • 55449107110 scopus 로고    scopus 로고
    • The L-Type Ca+ and KATP channels may contribute to pacing-induced protection against anoxia-reoxygenation in the embryonic heart model
    • 10.1111/j.1540-8167.2008.01218.x 18554212 10.1111/j.1540-8167.2008.01218. x
    • P Bruchez A Sarre L Kappenberger E Raddatz 2008 The L-Type Ca+ and KATP channels may contribute to pacing-induced protection against anoxia-reoxygenation in the embryonic heart model J Cardiovasc Electrophysiol 19 1196 1202 10.1111/j.1540-8167.2008.01218.x 18554212 10.1111/j.1540-8167.2008. 01218.x
    • (2008) J Cardiovasc Electrophysiol , vol.19 , pp. 1196-1202
    • Bruchez, P.1    Sarre, A.2    Kappenberger, L.3    Raddatz, E.4
  • 7
    • 0034819597 scopus 로고    scopus 로고
    • Maternal vascularisation of the human placenta: Does the embryo develop in a hypoxic environment?
    • DOI 10.1016/S1297-9589(01)00179-5
    • GJ Burton E Jaunaiux 2001 Maternal vascularisation of the human placenta: does the embryo develop in a hypoxic environment? Gynecol Obstet Fertil 29 503 508 10.1016/S1297-9589(01)00179-5 11575145 10.1016/S1297-9589(01)00179-5 1:STN:280:DC%2BD3MrivFeqsA%3D%3D (Pubitemid 32861433)
    • (2001) Gynecologie Obstetrique Fertilite , vol.29 , Issue.7-8 , pp. 503-508
    • Burton, G.J.1    Jaunaiux, E.2
  • 8
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • DOI 10.1006/abio.1987.9999
    • P Chomczynski N Sacchi 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 156 159 10.1006/abio.1987.99990003-2697(87)90021-2 2440339 10.1016/0003-2697(87)90021-2 1:CAS:528:DyaL2sXitFSns7Y%3D (Pubitemid 17064313)
    • (1987) Analytical Biochemistry , vol.162 , Issue.1 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 9
    • 52049124749 scopus 로고    scopus 로고
    • Of alphas and betas: Distinct and overlapping functions of STAT3 isoforms
    • 10.2741/3170 18508676 10.2741/3170 1:CAS:528:DC%2BD1cXnsVOit7c%3D
    • S Dewilde A Vercelli R Chiarle V Poli 2008 Of alphas and betas: distinct and overlapping functions of STAT3 isoforms Front Biosci 13 6501 6514 10.2741/3170 18508676 10.2741/3170 1:CAS:528:DC%2BD1cXnsVOit7c%3D
    • (2008) Front Biosci , vol.13 , pp. 6501-6514
    • Dewilde, S.1    Vercelli, A.2    Chiarle, R.3    Poli, V.4
  • 10
    • 16444366811 scopus 로고    scopus 로고
    • JAK2/STAT3 directs cardiomyogenesis within murine embryonic stem cells in vitro
    • DOI 10.1634/stemcells.2004-0293
    • K Foshay G Rodriguez B Hoel J Narayan GI Gallicano 2005 JAK2/STAT3 directs cardiomyogenesis within murine embryonic stem cells in vitro Stem Cells 23 530 543 10.1634/stemcells.2004-0293 15790774 10.1634/stemcells.2004-0293 1:CAS:528:DC%2BD2MXjslGjs7w%3D (Pubitemid 40478492)
    • (2005) Stem Cells , vol.23 , Issue.4 , pp. 530-543
    • Foshay, K.1    Rodriguez, G.2    Hoel, B.3    Narayan, J.4    Gallicano, G.I.5
  • 11
    • 50249152907 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion
    • 10.1007/s00395-008-0728-x 18500485 10.1007/s00395-008-0728-x 1:CAS:528:DC%2BD1cXhtVOgu7vL
    • BN Fuglesteg N Suleman C Tiron T Kanhema L Lacerda TV Andreasen MN Sack AK Jonassen OD Mjos LH Opie S Lecour 2008 Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion Basic Res Cardiol 103 444 453 10.1007/s00395-008-0728-x 18500485 10.1007/s00395-008-0728-x 1:CAS:528:DC%2BD1cXhtVOgu7vL
    • (2008) Basic Res Cardiol , vol.103 , pp. 444-453
    • Fuglesteg, B.N.1    Suleman, N.2    Tiron, C.3    Kanhema, T.4    Lacerda, L.5    Andreasen, T.V.6    Sack, M.N.7    Jonassen, A.K.8    Mjos, O.D.9    Opie, L.H.10    Lecour, S.11
  • 12
    • 77954427217 scopus 로고    scopus 로고
    • Transient anoxia and oxyradicals induce a region-specific activation of MAPKs in the embryonic heart
    • doi: 10.1007/s11010-010-0423-8
    • Gardier S, Pedretti S, Sarre A, Raddatz E (2010) Transient anoxia and oxyradicals induce a region-specific activation of MAPKs in the embryonic heart. Mol Cell Biochem 340:239-247. doi: 10.1007/s11010-010-0423-8
    • (2010) Mol Cell Biochem , vol.340 , pp. 239-247
    • Gardier, S.1    Pedretti, S.2    Sarre, A.3    Raddatz, E.4
  • 13
    • 57049143783 scopus 로고    scopus 로고
    • Regulating RISK: A role for JAK-STAT signaling in postconditioning?
    • 10.1152/ajpheart.00692.2008 18708442 10.1152/ajpheart.00692.2008 1:CAS:528:DC%2BD1cXht1ymur%2FJ
    • MD Goodman SE Koch GA Fuller-Bicer KL Butler 2008 Regulating RISK: a role for JAK-STAT signaling in postconditioning? Am J Physiol Heart Circ Physiol 295 H1649 H1656 10.1152/ajpheart.00692.2008 18708442 10.1152/ajpheart.00692.2008 1:CAS:528:DC%2BD1cXht1ymur%2FJ
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Goodman, M.D.1    Koch, S.E.2    Fuller-Bicer, G.A.3    Butler, K.L.4
  • 14
    • 67649988989 scopus 로고    scopus 로고
    • Mitochondrial STAT3 supports Ras-dependent oncogenic transformation
    • 10.1126/science.1171721 19556508 10.1126/science.1171721 1:CAS:528:DC%2BD1MXnsFOmtrY%3D
    • DJ Gough A Corlett K Schlessinger J Wegrzyn AC Larner DE Levy 2009 Mitochondrial STAT3 supports Ras-dependent oncogenic transformation Science 324 1713 1716 10.1126/science.1171721 19556508 10.1126/science.1171721 1:CAS:528:DC%2BD1MXnsFOmtrY%3D
    • (2009) Science , vol.324 , pp. 1713-1716
    • Gough, D.J.1    Corlett, A.2    Schlessinger, K.3    Wegrzyn, J.4    Larner, A.C.5    Levy, D.E.6
  • 15
    • 33746859331 scopus 로고    scopus 로고
    • The JAK/STAT pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3β
    • DOI 10.1152/ajpheart.00003.2006
    • ER Gross AK Hsu GJ Gross 2006 The JAK/STAT pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3 beta Am J Physiol Heart Circ Physiol 291 H827 H834 10.1152/ajpheart.00003.2006 16517948 10.1152/ajpheart.00003.2006 1:CAS:528:DC%2BD28XoslWrurw%3D (Pubitemid 44175091)
    • (2006) American Journal of Physiology - Heart and Circulatory Physiology , vol.291 , Issue.2
    • Gross, E.R.1    Hsu, A.K.2    Gross, G.J.3
  • 16
    • 84924926133 scopus 로고
    • A series of normal stages in the development of the chick embryo
    • 10.1002/aja.1001950404 10.1002/jmor.1050880104
    • V Hamburger H Hamilton 1951 A series of normal stages in the development of the chick embryo J Morphol 88 49 92 10.1002/aja.1001950404 10.1002/jmor.1050880104
    • (1951) J Morphol , vol.88 , pp. 49-92
    • Hamburger, V.1    Hamilton, H.2
  • 17
    • 79952844781 scopus 로고    scopus 로고
    • RISK and SAFE pro-survival signalling pathways in ischaemic postconditioning: Two sides of the same coin
    • 2010 Oct 26 [epub ahead of print]. doi: 10.1089/ars.2010.3360
    • Hausenloy DJ, Lecour S, Yellon DM (2010) RISK and SAFE pro-survival signalling pathways in ischaemic postconditioning: two sides of the same coin. Antioxid Redox Signal 2010 Oct 26 [epub ahead of print]. doi: 10.1089/ars.2010.3360
    • (2010) Antioxid Redox Signal
    • Hausenloy, D.J.1    Lecour, S.2    Yellon, D.M.3
  • 18
    • 33646047765 scopus 로고    scopus 로고
    • Survival kinases in ischemic preconditioning and postconditioning
    • 10.1016/j.cardiores.2006.01.017 16545352 10.1016/j.cardiores.2006.01.017 1:CAS:528:DC%2BD28XjvVGjurs%3D
    • DJ Hausenloy DM Yellon 2006 Survival kinases in ischemic preconditioning and postconditioning Cardiovasc Res 70 240 253 10.1016/j.cardiores.2006.01.017 16545352 10.1016/j.cardiores.2006.01.017 1:CAS:528:DC%2BD28XjvVGjurs%3D
    • (2006) Cardiovasc Res , vol.70 , pp. 240-253
    • Hausenloy, D.J.1    Yellon, D.M.2
  • 19
    • 57149142506 scopus 로고    scopus 로고
    • Cardioprotection: Nitric oxide, protein kinases, and mitochondria
    • 10.1161/CIRCULATIONAHA.108.805242 18981312 10.1161/CIRCULATIONAHA.108. 805242
    • G Heusch K Boengler R Schulz 2008 Cardioprotection: nitric oxide, protein kinases, and mitochondria Circulation 118 1915 1919 10.1161/CIRCULATIONAHA.108. 805242 18981312 10.1161/CIRCULATIONAHA.108.805242
    • (2008) Circulation , vol.118 , pp. 1915-1919
    • Heusch, G.1    Boengler, K.2    Schulz, R.3
  • 20
    • 0034023759 scopus 로고    scopus 로고
    • The Jak-STAT pathway
    • DOI 10.1016/S0161-5890(00)00018-3, PII S0161589000000183
    • K Imada WJ Leonard 2000 The Jak-STAT pathway Mol Immunol 37 1 11 S0161589000000183 10781830 10.1016/S0161-5890(00)00018-3 1:CAS:528: DC%2BD3cXjslCmtLc%3D (Pubitemid 30316189)
    • (2000) Molecular Immunology , vol.37 , Issue.1-2 , pp. 1-11
    • Imada, K.1    Leonard, W.J.2
  • 21
    • 0033067007 scopus 로고    scopus 로고
    • Dynamics of fetal circulatory responses to hypoxia and asphyxia
    • DOI 10.1016/S0301-2115(98)00325-X, PII S030121159800325X
    • A Jensen Y Garnier R Berger 1999 Dynamics of fetal circulatory responses to hypoxia and asphyxia Eur J Obstet Gynecol Reprod Biol 84 155 172 S030121159800325X 10428339 10.1016/S0301-2115(98)00325-X 1:STN:280: DyaK1MzlsFaqsQ%3D%3D (Pubitemid 29248916)
    • (1999) European Journal of Obstetrics Gynecology and Reproductive Biology , vol.84 , Issue.2 , pp. 155-172
    • Jensen, A.1    Garnier, Y.2    Berger, R.3
  • 22
    • 78649323182 scopus 로고    scopus 로고
    • Ethanolamine is a novel STAT-3 dependent cardioprotective agent
    • 10.1007/s00395-010-0125-0 20938668 10.1007/s00395-010-0125-0 1:CAS:528:DC%2BC3cXhtlClu7bO
    • RF Kelly KT Lamont S Somers D Hacking L Lacerda P Thomas LH Opie S Lecour 2010 Ethanolamine is a novel STAT-3 dependent cardioprotective agent Basic Res Cardiol 105 763 770 10.1007/s00395-010-0125-0 20938668 10.1007/s00395-010-0125-0 1:CAS:528:DC%2BC3cXhtlClu7bO
    • (2010) Basic Res Cardiol , vol.105 , pp. 763-770
    • Kelly, R.F.1    Lamont, K.T.2    Somers, S.3    Hacking, D.4    Lacerda, L.5    Thomas, P.6    Opie, L.H.7    Lecour, S.8
  • 23
    • 78049231452 scopus 로고    scopus 로고
    • Circadian profiles in the embryonic chick heart: L-type voltage-gated calcium channels and signaling pathways
    • 10.3109/07420528.2010.514631 20969517 10.3109/07420528.2010.514631 1:CAS:528:DC%2BC3cXhtlehtrnK
    • ML Ko L Shi K Grushin F Nigussie GY Ko 2010 Circadian profiles in the embryonic chick heart: L-type voltage-gated calcium channels and signaling pathways Chronobiol Int 27 1673 1696 10.3109/07420528.2010.514631 20969517 10.3109/07420528.2010.514631 1:CAS:528:DC%2BC3cXhtlehtrnK
    • (2010) Chronobiol Int , vol.27 , pp. 1673-1696
    • Ko, M.L.1    Shi, L.2    Grushin, K.3    Nigussie, F.4    Ko, G.Y.5
  • 24
    • 34547951341 scopus 로고    scopus 로고
    • Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling
    • DOI 10.1097/FJC.0b013e318068dd49, PII 0000534420070800000005
    • M Kurdi GW Booz 2007 Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling J Cardiovasc Pharmacol 50 126 141 10.1097/FJC. 0b013e318068dd4900005344-200708000-00005 17703129 10.1097/FJC.0b013e318068dd49 1:CAS:528:DC%2BD2sXptFemsbo%3D (Pubitemid 47267738)
    • (2007) Journal of Cardiovascular Pharmacology , vol.50 , Issue.2 , pp. 126-141
    • Kurdi, M.1    Booz, G.W.2
  • 25
    • 78649318067 scopus 로고    scopus 로고
    • TNFalpha protects cardiac mitochondria independently of its cell surface receptors
    • 10.1007/s00395-010-0113-4 20680307 10.1007/s00395-010-0113-4 1:CAS:528:DC%2BC3cXhtlClu7nF
    • L Lacerda J McCarthy SF Mungly EG Lynn MN Sack LH Opie S Lecour 2010 TNFalpha protects cardiac mitochondria independently of its cell surface receptors Basic Res Cardiol 105 751 762 10.1007/s00395-010-0113-4 20680307 10.1007/s00395-010-0113-4 1:CAS:528:DC%2BC3cXhtlClu7nF
    • (2010) Basic Res Cardiol , vol.105 , pp. 751-762
    • Lacerda, L.1    McCarthy, J.2    Mungly, S.F.3    Lynn, E.G.4    Sack, M.N.5    Opie, L.H.6    Lecour, S.7
  • 26
    • 71549129836 scopus 로고    scopus 로고
    • Ischemic postconditioning protects against reperfusion injury via the SAFE pathway
    • 10.1093/cvr/cvp274 19666677 10.1093/cvr/cvp274 1:CAS:528: DC%2BD1MXht1OrtLjI
    • L Lacerda S Somers LH Opie S Lecour 2009 Ischemic postconditioning protects against reperfusion injury via the SAFE pathway Cardiovasc Res 84 201 208 10.1093/cvr/cvp274 19666677 10.1093/cvr/cvp274 1:CAS:528:DC%2BD1MXht1OrtLjI
    • (2009) Cardiovasc Res , vol.84 , pp. 201-208
    • Lacerda, L.1    Somers, S.2    Opie, L.H.3    Lecour, S.4
  • 27
    • 27144547642 scopus 로고    scopus 로고
    • Peroxynitrite is a potent inhibitor of NF-κB activation triggered by inflammatory stimuli in cardiac and endothelial cell lines
    • DOI 10.1074/jbc.M501977200
    • S Levrand B Pesse F Feihl B Waeber P Pacher J Rolli MD Schaller L Liaudet 2005 Peroxynitrite is a potent inhibitor of NF-{kappa}B activation triggered by inflammatory stimuli in cardiac and endothelial cell lines J Biol Chem 280 34878 34887 10.1074/jbc.M501977200 16079150 10.1074/jbc.M501977200 1:CAS:528:DC%2BD2MXhtVyks7%2FP (Pubitemid 41504622)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.41 , pp. 34878-34887
    • Levrand, S.1    Pesse, B.2    Feihl, F.3    Waeber, B.4    Pacher, P.5    Rolli, J.6    Schaller, M.-D.7    Liaudet, L.8
  • 28
    • 33750040230 scopus 로고    scopus 로고
    • Structure, function, and regulation of STAT proteins
    • DOI 10.1039/b606246f
    • CP Lim X Cao 2006 Structure, function, and regulation of STAT proteins Mol Biosyst 2 536 550 10.1039/b606246f 17216035 10.1039/b606246f 1:CAS:528:DC%2BD28Xht1yjt7nO (Pubitemid 44583902)
    • (2006) Molecular BioSystems , vol.2 , Issue.11 , pp. 536-550
    • Lim, C.P.1    Cao, X.2
  • 29
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • KJ Livak TD Schmittgen 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 402 408 10.1006/meth.2001.1262S1046-2023(01)91262-9 11846609 10.1006/meth.2001.1262 1:CAS:528:DC%2BD38XhtFelt7s%3D (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 30
    • 42549116145 scopus 로고    scopus 로고
    • JAK/STAT and PI3K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes
    • DOI 10.1159/000129389
    • Y Lu J Zhou C Xu H Lin J Xiao Z Wang B Yang 2008 JAK/STAT and PI3 K/AKT pathways form a mutual transactivation loop and afford resistance to oxidative stress-induced apoptosis in cardiomyocytes Cell Physiol Biochem 21 305 314 10.1159/000129389 18441519 10.1159/000129389 1:CAS:528:DC%2BD1cXltFeqt70%3D (Pubitemid 351591422)
    • (2008) Cellular Physiology and Biochemistry , vol.21 , Issue.4 , pp. 305-314
    • Lu, Y.1    Zhou, J.2    Xu, C.3    Lin, H.4    Xiao, J.5    Wang, Z.6    Yang, B.7
  • 31
    • 0031969557 scopus 로고    scopus 로고
    • Oxygen, genes, and development: An analysis of the role of hypoxic gene regulation during murine vascular development
    • DOI 10.1007/s001090050231
    • E Maltepe MC Simon 1998 Oxygen, genes, and development: an analysis of the role of hypoxic gene regulation during murine vascular development J Mol Med 76 391 401 10.1007/s001090050231 9625296 10.1007/s001090050231 1:STN:280:DyaK1c3os12lsg%3D%3D (Pubitemid 28218641)
    • (1998) Journal of Molecular Medicine , vol.76 , Issue.6 , pp. 391-401
    • Maltepe, E.1    Simon, M.C.2
  • 32
    • 79955531844 scopus 로고    scopus 로고
    • Cellular signal processing
    • New York
    • Marks F, Klingmüller U, Müller-Decker K (2009) Cellular signal processing. Garland Science, New York, pp 194-196
    • (2009) Garland Science , pp. 194-196
    • Marks F, K.1
  • 34
    • 34447119530 scopus 로고    scopus 로고
    • Resolution of the nuclear localization mechanism of glycogen synthase kinase-3: Functional effects in apoptosis
    • DOI 10.1074/jbc.M700610200
    • GP Meares RS Jope 2007 Resolution of the nuclear localization mechanism of glycogen synthase kinase-3: functional effects in apoptosis J Biol Chem 282 16989 17001 10.1074/jbc.M700610200 17438332 10.1074/jbc.M700610200 1:CAS:528:DC%2BD2sXmt1agsb4%3D (Pubitemid 47093248)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.23 , pp. 16989-17001
    • Meares, G.P.1    Jope, R.S.2
  • 35
    • 67449156064 scopus 로고    scopus 로고
    • Nuclear and mitochondrial signalling Akts in cardiomyocytes
    • 10.1093/cvr/cvp087 19279164 10.1093/cvr/cvp087 1:CAS:528: DC%2BD1MXksVaktr0%3D
    • S Miyamoto M Rubio MA Sussman 2009 Nuclear and mitochondrial signalling Akts in cardiomyocytes Cardiovasc Res 82 272 285 10.1093/cvr/cvp087 19279164 10.1093/cvr/cvp087 1:CAS:528:DC%2BD1MXksVaktr0%3D
    • (2009) Cardiovasc Res , vol.82 , pp. 272-285
    • Miyamoto, S.1    Rubio, M.2    Sussman, M.A.3
  • 36
    • 0035964305 scopus 로고    scopus 로고
    • Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase
    • S Negoro K Kunisada Y Fujio M Funamoto MI Darville DL Eizirik T Osugi M Izumi Y Oshima Y Nakaoka H Hirota T Kishimoto K Yamauchi-Takihara 2001 Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase Circulation 104 979 981 10.1161/hc3401.095947 11524388 10.1161/hc3401.095947 1:CAS:528: DC%2BD3MXntlKju7g%3D (Pubitemid 32803871)
    • (2001) Circulation , vol.104 , Issue.9 , pp. 979-981
    • Negoro, S.1    Kunisada, K.2    Fujio, Y.3    Funamoto, M.4    Darville, M.I.5    Eizirik, D.L.6    Osugi, T.7    Izumi, M.8    Oshima, Y.9    Nakaoka, Y.10    Hirota, H.11    Kishimoto, T.12    Yamauchi-Takihara, K.13
  • 37
    • 0033838783 scopus 로고    scopus 로고
    • Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction
    • S0008-6363(00)00138-3 10974228 10.1016/S0008-6363(00)00138-3 1:CAS:528:DC%2BD3cXmt1Wqur4%3D
    • S Negoro K Kunisada E Tone M Funamoto H Oh T Kishimoto K Yamauchi-Takihara 2000 Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction Cardiovasc Res 47 797 805 S0008-6363(00)00138-3 10974228 10.1016/S0008-6363(00)00138-3 1:CAS:528:DC%2BD3cXmt1Wqur4%3D
    • (2000) Cardiovasc Res , vol.47 , pp. 797-805
    • Negoro, S.1    Kunisada, K.2    Tone, E.3    Funamoto, M.4    Oh, H.5    Kishimoto, T.6    Yamauchi-Takihara, K.7
  • 38
    • 33947423265 scopus 로고    scopus 로고
    • Thyroid hormone changes cardiomyocyte shape and geometry via ERK signaling pathway: Potential therapeutic implications in reversing cardiac remodeling?
    • DOI 10.1007/s11010-006-9323-3
    • C Pantos C Xinaris I Mourouzis V Malliopoulou E Kardami DV Cokkinos 2007 Thyroid hormone changes cardiomyocyte shape and geometry via ERK signaling pathway: potential therapeutic implications in reversing cardiac remodeling? Mol Cell Biochem 297 65 72 10.1007/s11010-006-9323-3 17024559 10.1007/s11010-006- 9323-3 1:CAS:528:DC%2BD2sXjtVSqsb4%3D (Pubitemid 46443530)
    • (2007) Molecular and Cellular Biochemistry , vol.297 , Issue.1-2 , pp. 65-72
    • Pantos, C.1    Xinaris, C.2    Mourouzis, I.3    Malliopoulou, V.4    Kardami, E.5    Cokkinos, D.V.6
  • 39
    • 33747758417 scopus 로고    scopus 로고
    • Physiopathology of the embryonic heart (with special emphasis on hypoxia and reoxygenation)
    • DOI 10.1016/j.ancard.2006.02.007, PII S000339280600014X, Cardiologie Fondamentale: Protection Cardiaque
    • E Raddatz S Gardier A Sarre 2006 Physiopathology of the embryonic heart (with special emphasis on hypoxia and reoxygenation) Ann Cardiol Angeiol (Paris) 55 79 89 10.1016/j.ancard.2006.02.007 10.1016/j.ancard.2006.02.007 1:STN:280:DC%2BD283otVWnug%3D%3D (Pubitemid 44274984)
    • (2006) Annales de Cardiologie et d'Angeiologie , vol.55 , Issue.2 , pp. 79-89
    • Raddatz, E.1    Gardier, S.2    Sarre, A.3
  • 40
    • 79955050520 scopus 로고    scopus 로고
    • Differential contribution of mitochondria, NADPH-oxidases and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart
    • 2010 Dec 30 [epub ahead of print]. doi: 10.1152/ajpheart.00827.2010
    • Raddatz E, Thomas AC, Sarre A, Benathan M (2010) Differential contribution of mitochondria, NADPH-oxidases and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart. Am J Physiol Heart Circ Physiol 2010 Dec 30 [epub ahead of print]. doi: 10.1152/ajpheart.00827.2010
    • (2010) Am J Physiol Heart Circ Physiol
    • Raddatz, E.1    Thomas, A.C.2    Sarre, A.3    Benathan, M.4
  • 41
    • 0034745337 scopus 로고    scopus 로고
    • Oxidative and glycogenolytic capacities within the developing chick heart
    • R Romano AC Rochat P Kucera Y De Ribaupierre E Raddatz 2001 Oxidative and glycogenolytic capacities within the developing chick heart Pediatr Res 49 363 372 0031-3998/01/4903-0363 11228262 10.1203/00006450-200103000-00010 1:CAS:528:DC%2BD3MXit1aktro%3D (Pubitemid 32205235)
    • (2001) Pediatric Research , vol.49 , Issue.3 , pp. 363-372
    • Romano, R.1    Rochat, A.-C.2    Kucera, P.3    De Ribaupierre, Y.4    Raddatz, E.5
  • 42
    • 67349210620 scopus 로고    scopus 로고
    • Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes
    • 10.1016/j.yjmcc.2009.02.022 19269295 10.1016/j.yjmcc.2009.02.022 1:CAS:528:DC%2BD1MXms1Ort74%3D
    • M Rubio D Avitabile K Fischer G Emmanuel N Gude S Miyamoto S Mishra EM Schaefer JH Brown MA Sussman 2009 Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes J Mol Cell Cardiol 47 96 103 10.1016/j.yjmcc. 2009.02.022 19269295 10.1016/j.yjmcc.2009.02.022 1:CAS:528:DC%2BD1MXms1Ort74%3D
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 96-103
    • Rubio, M.1    Avitabile, D.2    Fischer, K.3    Emmanuel, G.4    Gude, N.5    Miyamoto, S.6    Mishra, S.7    Schaefer, E.M.8    Brown, J.H.9    Sussman, M.A.10
  • 43
    • 44449172895 scopus 로고    scopus 로고
    • Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: Involvement of the Ca2+ and mitoKATP channels
    • 10.1007/s11010-008-9750-4 18418700 10.1007/s11010-008-9750-4 1:CAS:528:DC%2BD1cXmtlSru7k%3D
    • A Sarre S Gardier F Maurer C Bonny E Raddatz 2008 Modulation of the c-Jun N-terminal kinase activity in the embryonic heart in response to anoxia-reoxygenation: involvement of the Ca2+ and mitoKATP channels Mol Cell Biochem 313 133 138 10.1007/s11010-008-9750-4 18418700 10.1007/s11010-008-9750-4 1:CAS:528:DC%2BD1cXmtlSru7k%3D
    • (2008) Mol Cell Biochem , vol.313 , pp. 133-138
    • Sarre, A.1    Gardier, S.2    Maurer, F.3    Bonny, C.4    Raddatz, E.5
  • 44
    • 15744366406 scopus 로고    scopus 로고
    • ATP channel activation in the postanoxic developing heart protects E-C coupling via NO-, ROS-, and PKC-dependent pathways
    • DOI 10.1152/ajpheart.00942.2004
    • A Sarre N Lange P Kucera E Raddatz 2005 mitoKATP channel activation in the postanoxic developing heart protects E-C coupling via NO-, ROS-, and PKC-dependent pathways Am J Physiol Heart Circ Physiol 288 H1611 H1619 10.1152/ajpheart.00942.2004 15550517 10.1152/ajpheart.00942.2004 1:CAS:528:DC%2BD2MXjtlOrt7w%3D (Pubitemid 40417983)
    • (2005) American Journal of Physiology - Heart and Circulatory Physiology , vol.288 , Issue.4
    • Sarre, A.1    Lange, N.2    Kucera, P.3    Raddatz, E.4
  • 45
    • 33751322950 scopus 로고    scopus 로고
    • Arrhythmogenesis in the developing heart during anoxia-reoxygenation and hypothermia-rewarming: An in vitro model
    • DOI 10.1111/j.1540-8167.2006.00637.x
    • A Sarre P Maury P Kucera L Kappenberger E Raddatz 2006 Arrhythmogenesis in the developing heart during anoxia-reoxygenation and hypothermia-rewarming: an in vitro model J Cardiovasc Electrophysiol 17 1350 1359 10.1111/j.1540-8167. 2006.00637.x 17014683 10.1111/j.1540-8167.2006.00637.x (Pubitemid 44808558)
    • (2006) Journal of Cardiovascular Electrophysiology , vol.17 , Issue.12 , pp. 1350-1359
    • Sarre, A.1    Maury, P.2    Kucera, P.3    Kappenberger, L.4    Raddatz, E.5
  • 46
    • 72749090082 scopus 로고    scopus 로고
    • Specific inhibition of HCN channels slows rhythm differently in atria, ventricle and outflow tract and stabilizes conduction in the anoxic-reoxygenated embryonic heart model
    • 10.1016/j.phrs.2009.09.007 19818405 10.1016/j.phrs.2009.09.007 1:CAS:528:DC%2BC3cXotlyq
    • A Sarre S Pedretti S Gardier E Raddatz 2010 Specific inhibition of HCN channels slows rhythm differently in atria, ventricle and outflow tract and stabilizes conduction in the anoxic-reoxygenated embryonic heart model Pharmacol Res 61 85 91 10.1016/j.phrs.2009.09.007 19818405 10.1016/j.phrs.2009.09.007 1:CAS:528:DC%2BC3cXotlyq
    • (2010) Pharmacol Res , vol.61 , pp. 85-91
    • Sarre, A.1    Pedretti, S.2    Gardier, S.3    Raddatz, E.4
  • 47
    • 0030611426 scopus 로고    scopus 로고
    • Functional differences between Stat3alpha and Stat3beta
    • 0270-7306/97/$04.0010 9271408 1:CAS:528:DyaK2sXlslartL4%3D
    • TS Schaefer LK Sanders OK Park D Nathans 1997 Functional differences between Stat3alpha and Stat3beta Mol Cell Biol 17 5307 5316 0270-7306/97/ $04.0010 9271408 1:CAS:528:DyaK2sXlslartL4%3D
    • (1997) Mol Cell Biol , vol.17 , pp. 5307-5316
    • Schaefer, T.S.1    Sanders, L.K.2    Park, O.K.3    Nathans, D.4
  • 48
    • 0036340546 scopus 로고    scopus 로고
    • Developmental changes in cardiac recovery from anoxia-reoxygenation
    • 10.1152/ajpregu.00534.2001 12121851 1:CAS:528:DC%2BD38XmslShsbc%3D
    • D Sedmera P Kucera E Raddatz 2002 Developmental changes in cardiac recovery from anoxia-reoxygenation Am J Physiol Regul Integr Comp Physiol 283 R379 R388 10.1152/ajpregu.00534.2001 12121851 1:CAS:528:DC%2BD38XmslShsbc%3D
    • (2002) Am J Physiol Regul Integr Comp Physiol , vol.283
    • Sedmera, D.1    Kucera, P.2    Raddatz, E.3
  • 49
    • 0034176265 scopus 로고    scopus 로고
    • Developmental patterning of the myocardium
    • DOI 10.1002/(SICI)1097-0185(20000401)258:4<319::AID-AR1>3.0.CO;2-O
    • D Sedmera T Pexieder M Vuillemin RP Thompson RH Anderson 2000 Developmental patterning of the myocardium Anat Rec 258 319 337 10.1002/(SICI)1097-0185(20000401)258:4<319::AID-AR1>3.0.CO;2-O 10737851 10.1002/(SICI)1097-0185(20000401)258:4<319::AID-AR1>3.0.CO;2-O 1:STN:280:DC%2BD3c3gt1SisA%3D%3D (Pubitemid 30187458)
    • (2000) Anatomical Record , vol.258 , Issue.4 , pp. 319-337
    • Sedmera, D.1    Pexieder, T.2    Vuillemin, M.3    Thompson, R.P.4    Anderson, R.H.5
  • 50
    • 59649114814 scopus 로고    scopus 로고
    • Ischemic postconditioning in pigs: No causal role for RISK activation
    • 10.1161/CIRCRESAHA.108.186429 19038864 10.1161/CIRCRESAHA.108.186429 1:CAS:528:DC%2BD1cXhsFSmt7%2FJ
    • A Skyschally P van Caster K Boengler P Gres J Musiolik D Schilawa R Schulz G Heusch 2009 Ischemic postconditioning in pigs: no causal role for RISK activation Circ Res 104 15 18 10.1161/CIRCRESAHA.108.186429 19038864 10.1161/CIRCRESAHA.108.186429 1:CAS:528:DC%2BD1cXhsFSmt7%2FJ
    • (2009) Circ Res , vol.104 , pp. 15-18
    • Skyschally, A.1    Van Caster, P.2    Boengler, K.3    Gres, P.4    Musiolik, J.5    Schilawa, D.6    Schulz, R.7    Heusch, G.8
  • 51
    • 0034085912 scopus 로고    scopus 로고
    • Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters
    • A Stephanou BK Brar RA Knight DS Latchman 2000 Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters Cell Death Differ 7 329 330 10.1038/sj.cdd.4400656 10866494 10.1038/sj.cdd.4400656 1:CAS:528: DC%2BD3cXis1Clsro%3D (Pubitemid 30192982)
    • (2000) Cell Death and Differentiation , vol.7 , Issue.3 , pp. 329-330
    • Stephanou, A.1    Brar, B.K.2    Knight, R.A.3    Latchman, D.S.4
  • 52
    • 45849120527 scopus 로고    scopus 로고
    • Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning
    • DOI 10.1093/cvr/cvn067
    • N Suleman S Somers R Smith LH Opie S Lecour 2008 Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning Cardiovasc Res 79 127 133 10.1093/cvr/cvn067 18339648 10.1093/cvr/cvn067 1:CAS:528:DC%2BD1cXnt1Skt7Y%3D (Pubitemid 351881934)
    • (2008) Cardiovascular Research , vol.79 , Issue.1 , pp. 127-133
    • Suleman, N.1    Somers, S.2    Smith, R.3    Opie, L.H.4    Lecour, S.C.5
  • 54
    • 0031951794 scopus 로고    scopus 로고
    • Effects of verapamil and ryanodine on activity of the embryonic chick heart during anoxia and reoxygenation
    • DOI 10.1097/00005344-199802000-00004
    • D Tenthorey Y de Ribaupierre P Kucera E Raddatz 1998 Effects of verapamil and ryanodine on activity of the embryonic chick heart during anoxia and reoxygenation J Cardiovasc Pharmacol 31 195 202 00005344-199802000-00004 9475260 10.1097/00005344-199802000-00004 1:CAS:528:DyaK1cXotFWnug%3D%3D (Pubitemid 28099159)
    • (1998) Journal of Cardiovascular Pharmacology , vol.31 , Issue.2 , pp. 195-202
    • Tenthorey, D.1    De Ribaupierre, Y.2    Kucera, P.3    Raddatz, E.4
  • 56
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • 0092-8674(95)90311-9 7543024 10.1016/0092-8674(95)90311-9 1:CAS:528:DyaK2MXnt1Gltrk%3D
    • Z Wen Z Zhong JE Darnell Jr 1995 Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation Cell 82 241 250 0092-8674(95)90311-9 7543024 10.1016/0092-8674(95)90311-9 1:CAS:528:DyaK2MXnt1Gltrk%3D
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell, Jr.J.E.3


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