Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts

Journal of Molecular and Cellular Cardiology

Volumn 47, Issue 5, 2009, Pages 684-690

  Xi, Jinkun ^a,b   McIntosh, Rachel ^a   Shen, Xiangjun ^a   Lee, SungRyul ^a   Chanoit, Guillaume ^a   Criswell, Hugh ^a   Zvara, David A ^a   Xu, Zhelong ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b NORTH CHINA COAL MEDICAL COLLEGE   (China)

Author keywords

Adenosine A2 receptors; GSK 3 ; mPTP; NECA; Reperfusion injury

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2 RECEPTOR AGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE A2B RECEPTOR; ADENOSINE A2B RECEPTOR AGONIST; ADENOSINE A2B RECEPTOR ANTAGONIST; BAY 60 6583; CGS 21860; GLYCOGEN SYNTHASE KINASE 3BETA; MITOCHONDRIAL ENZYME; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MRS 1706; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; ISOLATED HEART; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION SWELLING; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; ANIMAL; CHEMICALLY INDUCED DISORDER; CONFOCAL MICROSCOPY; DRUG EFFECT; GENETICS; HEART; HEART MUSCLE; HEART MUSCLE CELL; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT;

RATTUS;

ADENOSINE-5'-(N-ETHYLCARBOXAMIDE); ANIMALS; BLOTTING, WESTERN; HEART; MALE; MICROSCOPY, CONFOCAL; MYOCARDIUM; MYOCYTES, CARDIAC; RATS; RATS, WISTAR; RECEPTOR, ADENOSINE A2A; RECEPTOR, ADENOSINE A2B; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VASODILATOR AGENTS;

EID: 70349751969     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.08.009     Document Type: Article

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