Prolonged glutamate excitotoxicity increases GluR1 immunoreactivity but decreases mRNA of GluR1 and associated regulatory proteins in dissociated rat retinae in vitro

Biochimie

Volumn 112, Issue , 2015, Pages 160-171

  Challenor, Michael ^a   O'Hare Doig, Ryan ^a   Fuller, Paula ^a   Giacci, Marcus ^a   Bartlett, Carole ^a   Wale, Celeste H ^a   Cozens, Greg S ^a   Hool, Livia ^a,b   Dunlop, Sarah ^a   Swaminathan Iyer, K ^a   Rodger, Jennifer ^a   Fitzgerald, Melinda ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

Author keywords

AMPA receptor; Calcium; Cornichon; Glutamate excitotoxicity; Retina

Indexed keywords

AMPA RECEPTOR; CALCIUM; CHLORPHENIRAMINE MALEATE PLUS PHENYLEPHRINE; GLUR1 REGULATORY PROTEIN; GLUTAMIC ACID; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; REGULATOR PROTEIN; UNCLASSIFIED DRUG; CNIH-2 PROTEIN, RAT; CNIH-3 PROTEIN, RAT; DLGH1 PROTEIN, RAT; EYE PROTEIN; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AMPLICON; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CONTROLLED STUDY; EXCITOTOXICITY; GENE EXPRESSION; GLIA CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; NEGATIVE FEEDBACK; NERVE CELL; NONHUMAN; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA; RETINA CELL; RETINA GANGLION CELL; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; DOWN REGULATION; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; RETINA DISEASE;

RATTUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; DOWN-REGULATION; EYE PROTEINS; GLUTAMIC ACID; MEMBRANE PROTEINS; RATS; RECEPTORS, AMPA; RETINA; RETINAL DISEASES;

EID: 84925448615     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2015.03.008     Document Type: Article

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