Down-regulation of the RNA editing enzyme ADAR2 contributes to RGC death in a mouse model of glaucoma

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Wang, Ai Ling ^a   Carroll, Reed C ^a   Nawy, Scott ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 NAPHTHYLACETYLSPERMINE; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE ACTING ON RNA 2; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; CALCIUM ION; CALCIUM PERMEABLE AMPA RECEPTOR; COBALT; GLUTAMATE RECEPTOR 2; GLUTAMIC ACID; UNCLASSIFIED DRUG; ADAR2 PROTEIN, MOUSE; RNA BINDING PROTEIN; SMALL INTERFERING RNA;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; EXCITOTOXICITY; FEMALE; GENE SILENCING; GLAUCOMA; IN VITRO STUDY; INTRAOCULAR HYPERTENSION; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; RETINA GANGLION CELL; RNA EDITING; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DEATH; DISEASE MODEL; ENZYMOLOGY; GENETICS; INTRAOCULAR PRESSURE; METABOLISM; NICK END LABELING; PATHOLOGY; PATHOPHYSIOLOGY; STAINING;

ADENOSINE DEAMINASE; ANIMALS; CELL DEATH; CELLS, CULTURED; COBALT; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; GENE KNOCKDOWN TECHNIQUES; GLAUCOMA; IN SITU NICK-END LABELING; INTRAOCULAR PRESSURE; MICE, INBRED C57BL; RECEPTORS, AMPA; RETINAL GANGLION CELLS; RNA EDITING; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; STAINING AND LABELING;

EID: 84897417116     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091288     Document Type: Article

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