Calcium controls gene expression via three distinct pathways that can function independently of the Ras/mitogen-activated protein kinases (ERKs) signaling cascade

Journal of Neuroscience

Volumn 17, Issue 16, 1997, Pages 6189-6202

  Johnson, Claire M ^a   Hill, Caroline S ^b,c   Chawla, Sangeeta ^a   Treisman, Richard ^b   Bading, Hilmar ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^c LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

Author keywords

C fos; Calcium signaling; Cyclic AMP response element; Gene regulation; Serum response element; Ternary complex factor

Indexed keywords

CALCIUM; MITOGEN ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; GENE EXPRESSION REGULATION; MEMORY; NERVE CELL PLASTICITY; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

EID: 0030855640     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-16-06189.1997     Document Type: Article

References (61)

1. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K, editors (1987) Current protocols in molecular biology. New York: Greene and Wiley.
2. Bading H, Greenberg ME (1991) Stimulation of protein tyrosine phosphorylation by NMDA receptor activation. Science 253:912-914.
3. Bading H, Ginty DD, Greenberg ME (1993) Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 260:181-186.
4. Bading H, Segal MM, Sucher NJ, Dudek H, Lipton SA, Greenberg ME (1995) N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons. Neuroscience 64:653-664.
5. Bartel DF, Sheng M, Lau LF, Greenberg ME (1989) Growth factors and membrane depolarization activate distinct programs of early response gene expression: dissociation of fos and jun induction. Genes Dev 3:304-313.
6. Changelian PS, Feng P, King TC, Milbrandt J (1989) Structure of the NGFI-A gene and detection of upstream sequences responsible for its transcriptional induction by nerve growth factor. Proc Natl Acad Sci USA 86:377-381.
7. Christy B, Nathans D (1989) Functional serum response elements upstream of the growth factor-inducible gene zif 268. Mol Cell Biol 9:4889-4895.
8. Cole AJ, Saffen DW, Baraban JM, Worley PF (1989) Rapid increase of an immediate early gene messenger RNA in hippocampal neurons by synaptic NMDA receptor activation. Nature 340:474-476.
9. Dalton S, Treisman R (1992) Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell 68:597-612.
10. Darnell JE, Kerr IM, Stark GR (1994) Jak-STAT pathways and transcriptional regulation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421.
11. Feig LA, Cooper GM (1988) Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP. Mol Cell Biol 8:3235-3243.
12. Fu X-Y, Zhang J-J (1993) Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter. Cell 74:1135-1145.
13. Ghosh A, Greenberg ME (1995) Calcium signaling in neurons: molecular mechanisms and cellular consequences. Science 268:239-247.
14. TCF by MAP kinase stimulates ternary complex formation at c-fos promoter. Nature 358:414-417.
15. Gonzalez GA, Montminy MR (1989) Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680.
16. Graham R, Gilman M (1991) Distinct protein targets for signals acting at the c-fos serum response element. Science 251:189-192.
17. Hardingham GE, Chawla S, Johnson CM, Bading H (1997) Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature 385:260-265.
18. Hayes TE, Kichen AM, Cochran BH (1987) Inducible binding of a factor to the c-fos regulatory region. Proc Natl Acad Sci USA 84:1272-1276.
19. Hill CS, Treisman R (1995) Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G-proteins, and polypeptide growth factors. EMBO J 14:5037-5047.
20. Hill CS, Marais R, John S, Wynne J, Dalton S, Treisman R (1993) Functional analysis of a growth factor-responsive transcription factor complex. Cell 73:395-406.
21. Hill CS, Wynne J, Treisman R (1994) Serum-regulated transcription by serum response factor (SRF): a novel role for the DNA-binding domain. EMBO J 13:5421-5432.
22. Hill CS, Wynne J, Treisman R (1995) The Rho family GTPase RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81:1159-1170.
23. Hipskind RA, Rao VN, Mueller CG, Reddy ES, Nordheim A (1991) Ets-related protein Elk-1 is homologous to the c-fos regulatory factor p62TCF. Nature 354:531-534.
24. Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O (1994) Signaling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem Sci 19:222-227.
25. Impey S, Mark M, Villacres EC, Poser S, Chavkin C, Storm DR (1996) Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus. Neuron 16:973-982.
26. Janknecht R, Ernst WH, Pingoud V, Nordheim A (1993) Activation of TCF Elk-1 by MAP kinases. EMBO J 12:5097-5104.
27. 2+/calmodulin-dependent protein kinase type Gr in rat cerebellar cortex. Proc Natl Acad Sci USA 88:2850-2853.
28. Lerea LS, McNamara JO (1993) Ionotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways. Neuron 10:31-41.
29. Lerea LS, Butler LS, McNamara JO (1992) NMDA and non-NMDA receptor-mediated increase of c-fos mRNA in dentate gyms neurons involved calcium influx via different routes. J Neurosci 12:2973-2981.
30. Marais R, Wynne J, Treisman R (1993) The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 73:381-393.
31. Marshall CJ (1994) MAP kinase kinase kinase, MAP kinase kinase, and MAP kinase. Curr Opin Genet Dev 4:82-89.
32. Marshall CJ (1995) Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185.
33. Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, McKnight GS (1994) Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol Cell Biol 14:6107-6116.
34. 2+/calmodulin-dependent kinase. Mol Cell Biol 15:3672-3684.
35. Misra RP, Bonni A, Miranti CK, Rivera VM, Sheng M, Greenberg ME (1994) L-type voltage-sensitive calcium channel activation stimulates gene expression by a serum response factor-dependent pathway. J Biol Chem 269:25483-25493.
36. Morgan JL, Curran T (1991) Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu Rev Neurosci 14:421-451.
37. Norman C, Runswick M, Pollock R, Treisman R (1988) Isolation and properties of cDNA clones encoding SRF, a transcription factor that binds to the c-fos serum response element. Cell 55:989-1003.
38. Prywes R, Roeder RG (1987) Purification of the c-fos enhancer-binding protein. Mol Cell Biol 7:3482-3489.
39. Robertson LM, Kerppola TK, Vendrell M, Luk D, Smeyne RJ, Bocchiaro C, Morgan JI, Curran T (1995) Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron 14:241-252.
40. Rosen LB, Ginty DD, Weber MJ, Greenberg ME (1994) Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 12:1207-1221.
41. Rusanescu G, Qi H, Thomas SM, Brugge JS, Halegoua S (1995) Calcium influx induces neurite growth through a Src-Ras signaling cassette. Neuron 15:1415-1425.
42. Sadowski HB, Shuai K, Darnell Jr JE, Gilman MZ (1993) A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science 261:1739-1743.
43. Schröter H, Shaw PE, Nordheim A (1987) Purification of intercalator-released p67, a polypeptide that interacts specifically with the c-fos serum response element. Nucleic Acids Res 15:10145-10157.
44. Shaw P, Schröter H, Nordheim A (1989) The ability of a ternary complex to form over the serum response element correlates with serum inducibility of the c-fos promoter. Cell 56:563-572.
45. Sheng M, Greenberg ME (1990) The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 4:477-485.
46. Sheng M, Dougan ST, McFadden G, Greenberg ME (1988) Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol Cell Biol 8:2787-2796.
47. Sheng M, McFadden G, Greenberg ME (1990) Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4:571-582.
48. 2+-regulated transcription factor phosphorylated by calmodulin-dependent kinases. Science 252:1427-1430.
49. 2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev 8:2527-2539.
50. Thomas SM, DeMarco M, D'Arcangelo G, Halegoua S, Brugge JS (1992) Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68:1031-1040.
51. Treisman R (1985) Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences. Cell 42:889-902.
52. Treisman R (1987) Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J 6:2711-2717.
53. Treisman R (1994) Ternary complex factors: growth factor-regulated transcriptional activators. Curr Opin Genet Dev 4:96-101.
54. Treisman R, Marais R, Wynne J (1992) Spatial flexibility in ternary complexes between SRF and its accessory proteins. EMBO J 11:4631-4640.
55. Wagner BJ, Hayes TE, Hoban CJ, Cochran BH (1990) The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J 9:4477-4484.
56. Wisden W, Errington ML, Williams S, Dunnett SB, Waters C, Hitchcock D, Evan G, Bliss TVP, Hunt SP (1990) Differential expression of immediate early genes in the hippocampus and spinal cord. Neuron 4:603-614.
57. Wood KW, Sarnecki C, Roberts TM, Blenis J (1992) Ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK. Cell 68:1041-1050.
58. Worley PF, Bhat RV, Baraban JM, Erickson CA, McNaughton BL, Barnes CA (1993) Thresholds for synaptic activation of transcription factors in hippocampus: correlation with long-term enhancement. J Neurosci 13:4776-4786.
59. Xia Z, Dudek H, Miranti CK, Greenberg ME (1996) Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J Neurosci 16:5425-5436.
60. 2+ channel activator, in cardiac and vascular preparations. Mol Pharmacol 40:734-741.
61. Zhone Z, Wen Z, Darnell Jr JE (1994) Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6. Science 264:95-98.