Chronic low-dose glutamate is toxic to retinal ganglion cells: Toxicity blocked by memantine

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 8, 1996, Pages 1618-1624

  Vorwerk, Christian K ^a,d   Lipton, Stuart A ^b   Zurakowski, David ^b   Hyman, Brad T ^c   Sabel, Bernhard A ^d   Dreyer, Evan B ^a  

^a MASSACHUSETTS EYE AND EAR INFIRMARY   (United States)

^b Children's Hospital   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

chronic; glaucoma; glutamate; memantine; N methyl D aspartate; retinal ganglion cells

Indexed keywords

GLUTAMIC ACID; MEMANTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG MECHANISM; DRUG MIXTURE; GLAUCOMA; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVITREAL DRUG ADMINISTRATION; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL;

ANIMALS; ANTIPARKINSON AGENTS; CELL COUNT; CELL SURVIVAL; DOPAMINE AGENTS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; INJECTIONS, INTRAPERITONEAL; MEMANTINE; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; RETINAL GANGLION CELLS; VITREOUS BODY;

EID: 0029778159     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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