Tumor necrosis factor α increases neuronal vulnerability to excitotoxic necrosis by inducing expression of the AMPA-glutamate receptor subunit GluR1 via an acid sphingomyelinase-and NF-κB-dependent mechanism

Neurobiology of Disease

Volumn 11, Issue 1, 2002, Pages 199-213

  Yu, ZaiFang ^a   Cheng, Guanjun ^a   Wen, Xiaoming ^a   Wu, Gary D ^a   Lee, Wang Tso ^a   Pleasure, David ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Acid sphingomyelinase; AMPA receptor; Neuronal excitotoxicity; NF B; Tumor necrosis factor

Indexed keywords

GLUTAMATE RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KAINIC ACID; RECEPTOR SUBUNIT; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; KNOCKOUT MOUSE; MALE; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION;

EID: 0036449523     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1006/nbdi.2002.0530     Document Type: Article

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