Development of a systematic approach to rapid classification and identification of notoginsenosides and metabolites in rat feces based on liquid chromatography coupled triple time-of-flight mass spectrometry

Analytica Chimica Acta

Volumn 867, Issue , 2015, Pages 56-66

  Xing, Rong ^a,b   Zhou, Lijun ^a   Xie, Lin ^a   Hao, Kun ^a   Rao, Tai ^a   Wang, Qian ^a   Ye, Wei ^a   Fu, Hanxu ^a   Wang, Xinwen ^a   Wang, Guangji ^a   Liang, Yan ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b BENGBU MEDICAL COLLEGE   (China)

Author keywords

Chemicalome metabolome matching approach; Multiple product ions filtering; Neutral loss filtering; Notoginsenosides; Panax notoginseng extract

Indexed keywords

BIOMOLECULES; IONS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINE; RATS;

METABOLOMES; MULTIPLE PRODUCTS; NEUTRAL LOSS; NOTOGINSENOSIDES; PANAX NOTOGINSENG;

METABOLITES;

DRUG METABOLITE; GINSENOSIDE; GINSENOSIDE RB 1; GINSENOSIDE RB 2; GINSENOSIDE RD; GINSENOSIDE RE; GINSENOSIDE RF; GINSENOSIDE RG 1; GINSENOSIDE RG 2; GINSENOSIDE RG 3; GINSENOSIDE RH 1; NOTOGINSENOSIDE DERIVATIVE; NOTOGINSENOSIDE R1; PANAX NOTOGINSENG EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISSOCIATION; DRUG CLASSIFICATION; DRUG DETERMINATION; DRUG FECES LEVEL; DRUG STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PANAX NOTOGINSENG; PRIORITY JOURNAL; RAT; ANIMAL; CHEMISTRY; CHINESE MEDICINE; FECES; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT; TIME;

PANAX NOTOGINSENG; RATTUS;

ANIMALS; CHROMATOGRAPHY, LIQUID; FECES; GINSENOSIDES; MASS SPECTROMETRY; MEDICINE, CHINESE TRADITIONAL; PANAX NOTOGINSENG; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84925260601     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2015.02.039     Document Type: Article

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