MSM, an efficient workflow for metabolite identification using hybrid linear ion trap orbitrap mass spectrometer

Journal of the American Society for Mass Spectrometry

Volumn 23, Issue 5, 2012, Pages 880-888

  Cho, Robert ^a   Huang, Yingying ^b   Schwartz, Jae C ^b   Chen, Yan ^b   Carlson, Timothy J ^a   Ma, Ji ^a  

^a AMGEN INC   (United States)

^b Thermo Fisher Scientific   (United States)

Author keywords

Accurate mass filter; LC MS; Metabolite identification; MSM; Orbitrap; Wide isolation width HCD MS2

Indexed keywords

ACCURATE MASS; LC-MS; METABOLITE IDENTIFICATION; MSM; ORBITRAP; WIDE ISOLATION WIDTH HCD MS2;

DISSOCIATION; MASS SPECTROMETERS; METABOLITES; MOLECULES; OPTIMIZATION; RATS;

BIOMOLECULES;

DRUG METABOLITE; VERAPAMIL;

ANALYZER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE; CONTROLLED STUDY; DISSOCIATION; DRUG IDENTIFICATION; HYBRID LINEAR ION TRAP ORBITRAP MASS SPECTROMETER; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; LIVER CELL; MALE; MASS SPECTROMETER; MASS SPECTROMETRY; NONHUMAN; RAT; RELIABILITY; WORKFLOW;

ANIMALS; BILE; CHROMATOGRAPHY, LIQUID; HEPATOCYTES; MALE; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RATS; RATS, SPRAGUE-DAWLEY; VERAPAMIL;

EID: 84862556742     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-012-0351-9     Document Type: Article

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