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Volumn 55, Issue 4, 2014, Pages 371-391

Stem cells and cancer;Células madre y cáncer

Author keywords

Cancer; Carcinogenesis; Chemotherapy; Differentiation; Dormancy; Metastasis; Signaling pathway; Tumor stem cell

Indexed keywords

ARTICLE; CANCER RESEARCH; CANCER STEM CELL; DORMANCY; DRUG RESISTANCE; HUMAN; HUMAN CELL; METASTASIS; SIGNAL TRANSDUCTION; TUMOR RECURRENCE; ANIMAL; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL TRANSFORMATION; CLASSIFICATION; CYTOLOGY; DRUG EFFECTS; MOUSE; NEOPLASMS; PATHOLOGY; PHYSIOLOGY; RADIATION RESPONSE; STEM CELL; TUMOR EMBOLISM;

EID: 84925222288     PISSN: 05355133     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (146)
  • 1
    • 0035750515 scopus 로고    scopus 로고
    • Aspectos moleculares y celulares de la metástasis cancerosa
    • Arvelo F, Poupon MF. Aspectos moleculares y celulares de la metástasis cancerosa. Acta Cient Venez 2001; 52: 304-312.
    • (2001) Acta Cient Venez , vol.52 , pp. 304-312
    • Arvelo, F.1    Poupon, M.F.2
  • 2
    • 84863035821 scopus 로고    scopus 로고
    • Cancer stem cells: Distinct entities or dynamically regulated phenotypes?
    • Li Y, Laterra J. Cancer stem cells: Distinct entities or dynamically regulated phenotypes? Cancer Res 2012; 72: 576- 580.
    • (2012) Cancer Res , vol.72 , pp. 576-580
    • Li, Y.1    Laterra, J.2
  • 3
    • 0029154954 scopus 로고
    • The molecular basis of oncogenes and tumor suppressor genes
    • Weinberg RA. The molecular basis of oncogenes and tumor suppressor genes. Ann N Y Acad Sci 1995; 758: 331-338.
    • (1995) Ann N Y Acad Sci , vol.758 , pp. 331-338
    • Weinberg, R.A.1
  • 5
    • 33644826473 scopus 로고    scopus 로고
    • Roots and stems: Stem cells in cancer
    • Polyak K, Hahn WC. Roots and stems: stem cells in cancer. Nat Med 2006; 12: 296-300.
    • (2006) Nat Med , vol.12 , pp. 296-300
    • Polyak, K.1    Hahn, W.C.2
  • 6
    • 30644471961 scopus 로고    scopus 로고
    • Stem cells in the etiology and treatment of cancer
    • Zhang M, Rosen JM. Stem cells in the etiology and treatment of cancer. Curr Opin Genet Dev 2006; 16: 60-64.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 60-64
    • Zhang, M.1    Rosen, J.M.2
  • 7
    • 28544449786 scopus 로고    scopus 로고
    • A tumour stem cell hypothesis for the origins of prostate cancer
    • Maitland NJ, Collins A. A tumour stem cell hypothesis for the origins of prostate cancer. BJU Int 2005; 96: 1219-1223.
    • (2005) BJU Int , vol.96 , pp. 1219-1223
    • Maitland, N.J.1    Collins, A.2
  • 10
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004; 10: 789-799.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 12
    • 18744393752 scopus 로고    scopus 로고
    • Obtención de láminas de piel humana mediante ingeniería de tejidos
    • Arvelo F, Pérez P, Cotte C. Obtención de láminas de piel humana mediante ingeniería de tejidos. Acta Cient Venez 2004; 55: 74-82.
    • (2004) Acta Cient Venez , vol.55 , pp. 74-82
    • Arvelo, F.1    Pérez, P.2    Cotte, C.3
  • 13
    • 78149487692 scopus 로고    scopus 로고
    • Pluripotency and cellular reprogramming: Facts, hypotheses, unresolved issues
    • Hanna JH, Saha K, Jaenisch R. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 2010; 143: 508-525.
    • (2010) Cell , vol.143 , pp. 508-525
    • Hanna, J.H.1    Saha, K.2    Jaenisch, R.3
  • 15
    • 0020659677 scopus 로고
    • A stem cell model of human tumor growth: Implications for tumor cell clonogenic assays
    • Mackillop WJ, Ciampi A, Till JE, Buick RN. A stem cell model of human tumor growth: implications for tumor cell clonogenic assays. J Natl Cancer Inst 1983; 70:9-16.
    • (1983) J Natl Cancer Inst , vol.70 , pp. 9-16
    • Mackillop, W.J.1    Ciampi, A.2    Till, J.E.3    Buick, R.N.4
  • 16
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3: 730-737.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 17
    • 0030988803 scopus 로고    scopus 로고
    • Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo
    • Blair A, Hogge DE, Ailles LE, Lansdorp PM, Sutherland HJ. Lack of expression of Thy-1 (CD90) on acute myeloid leukemia cells with long-term proliferative ability in vitro and in vivo. Blood 1997; 89: 3104- 3112.
    • (1997) Blood , vol.89 , pp. 3104-3112
    • Blair, A.1    Hogge, D.E.2    Ailles, L.E.3    Lansdorp, P.M.4    Sutherland, H.J.5
  • 22
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007; 445: 106- 110.
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 30
  • 32
    • 2342601849 scopus 로고    scopus 로고
    • In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
    • Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol 2004; 6: 436-42.
    • (2004) Nat Cell Biol , vol.6 , pp. 436-442
    • Yuan, Y.1    Shen, H.2    Franklin, D.S.3    Scadden, D.T.4    Cheng, T.5
  • 33
    • 34047096557 scopus 로고    scopus 로고
    • Cancer stem cells: Models and concepts
    • Dalerba P, Cho RW, Clarke MF. Cancer stem cells: models and concepts. Annu Rev Med 2007; 58: 267-284.
    • (2007) Annu Rev Med , vol.58 , pp. 267-284
    • Dalerba, P.1    Cho, R.W.2    Clarke, M.F.3
  • 35
    • 84872169359 scopus 로고    scopus 로고
    • Leukaemic stem cells: Drug resistance, metastasis and therapeutic implications
    • Wong RS, Cheong SK. Leukaemic stem cells: drug resistance, metastasis and therapeutic implications. Malays J Pathol 2012; 34: 77-88.
    • (2012) Malays J Pathol , vol.34 , pp. 77-88
    • Wong, R.S.1    Cheong, S.K.2
  • 37
    • 84877990073 scopus 로고    scopus 로고
    • Seed, soil, and beyond: The basic biology of brain metastasis
    • Ramakrishna R, Rostomily R. Seed, soil, and beyond: The basic biology of brain metastasis. Surg Neurol Int 2013; 4: S256-264.
    • (2013) Surg Neurol Int , vol.4 , pp. S256-S264
    • Ramakrishna, R.1    Rostomily, R.2
  • 39
    • 84874400094 scopus 로고    scopus 로고
    • The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure
    • Chinn SB, Darr OA, Peters RD, Prince ME. The role of head and neck squamous cell carcinoma cancer stem cells in tumorigenesis, metastasis, and treatment failure. Front Endocrinol (Lausanne) 2012; 3: 1-6.
    • (2012) Front Endocrinol (Lausanne) , vol.3 , pp. 1-6
    • Chinn, S.B.1    Darr, O.A.2    Peters, R.D.3    Prince, M.E.4
  • 41
    • 84872689611 scopus 로고    scopus 로고
    • Prostate cancer stem cells: The case for model systems
    • Hynes PG, Kelly K. Prostate cancer stem cells: The case for model systems. J Carcinog 2012; 11: 1-19.
    • (2012) J Carcinog , vol.11 , pp. 1-19
    • Hynes, P.G.1    Kelly, K.2
  • 42
    • 72449196327 scopus 로고    scopus 로고
    • Telómero, telomerasa y cáncer
    • Arvelo F, Morales A. Telómero, telomerasa y cáncer. Acta Cient Venez 2004; 55: 288-303.
    • (2004) Acta Cient Venez , vol.55 , pp. 288-303
    • Arvelo, F.1    Morales, A.2
  • 43
    • 28444482382 scopus 로고    scopus 로고
    • Leukemic stem cells: Where do they come from?
    • Passegué E, Weisman IL. Leukemic stem cells: where do they come from? Stem Cell Rev 2005; 1: 181-188.
    • (2005) Stem Cell Rev , vol.1 , pp. 181-188
    • Passegué, E.1    Weisman, I.L.2
  • 44
    • 0141483064 scopus 로고    scopus 로고
    • Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
    • Passegué E, Jamieson CH, Ailles LE, Weissman IL. Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics? Proc Natl Acad Sci USA 2003; 100 (Suppl 1):11842-11849.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 11842-11849
    • Passegué, E.1    Jamieson, C.H.2    Ailles, L.E.3    Weissman, I.L.4
  • 45
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by definid factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by definid factors. Cell 2006; 126: 663-676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 47
    • 84855987633 scopus 로고    scopus 로고
    • Expression of stem cell and epithelialmesenchymal transition markers in primary breast cancer patients with circulating tumor cells
    • Kasimir-Bauer S, Hoffmann O, Wallwiener D, Kimmig R, Fehm T. Expression of stem cell and epithelialmesenchymal transition markers in primary breast cancer patients with circulating tumor cells. Breast Cancer Res 2012; 14: R15.
    • (2012) Breast Cancer Res , vol.14
    • Kasimir-Bauer, S.1    Hoffmann, O.2    Wallwiener, D.3    Kimmig, R.4    Fehm, T.5
  • 48
    • 84864865194 scopus 로고    scopus 로고
    • Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity
    • Akunuru S, James Zhai Q, Zheng Y. Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity. Cell Death Dis 2012; 3:1-10.
    • (2012) Cell Death Dis , vol.3 , pp. 1-10
    • Akunuru, S.1    James Zhai, Q.2    Zheng, Y.3
  • 49
    • 84857375987 scopus 로고    scopus 로고
    • Epithelial-tomesenchymal and mesenchymal-to-epithelial transitions in the colon
    • Sipos F, Galamb O. Epithelial-tomesenchymal and mesenchymal-to-epithelial transitions in the colon. World J Gastroenterol 2012; 18: 601-608.
    • (2012) World J Gastroenterol , vol.18 , pp. 601-608
    • Sipos, F.1    Galamb, O.2
  • 50
    • 67449092765 scopus 로고    scopus 로고
    • Cancer stem cells and their niche
    • Iwasaki H, Suda T. Cancer stem cells and their niche. Cancer Sci 2009; 100: 1166-1172.
    • (2009) Cancer Sci , vol.100 , pp. 1166-1172
    • Iwasaki, H.1    Suda, T.2
  • 51
    • 33646428091 scopus 로고    scopus 로고
    • Normal stem cells and cancer stem cells: The niche matters
    • Li L, Neaves WB. Normal stem cells and cancer stem cells: the niche matters. Cancer Res 2006; 66: 4553-4557.
    • (2006) Cancer Res , vol.66 , pp. 4553-4557
    • Li, L.1    Neaves, W.B.2
  • 52
    • 84856078085 scopus 로고    scopus 로고
    • A family business: Stem cell progeny join the niche to regulate homeostasis
    • Hsu YC, Fuchs E. A family business: stem cell progeny join the niche to regulate homeostasis. Nat Rev Mol Cell Biol 2012; 13: 103-114.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 103-114
    • Hsu, Y.C.1    Fuchs, E.2
  • 53
    • 84867371279 scopus 로고    scopus 로고
    • Asymmetric stem cell division: Precision for robustness
    • Inaba M, Yamashita YM. Asymmetric stem cell division: precision for robustness. Cell Stem Cell 2012; 11: 461-469.
    • (2012) Cell Stem Cell , vol.11 , pp. 461-469
    • Inaba, M.1    Yamashita, Y.M.2
  • 55
    • 79960896892 scopus 로고    scopus 로고
    • Cell fusion hypothesis of the cancer stem cell
    • Lu X, Kang Y. Cell fusion hypothesis of the cancer stem cell. Adv Exp Med Biol 2011; 714: 129-140.
    • (2011) Adv Exp Med Biol , vol.714 , pp. 129-140
    • Lu, X.1    Kang, Y.2
  • 56
    • 79960900961 scopus 로고    scopus 로고
    • Cell fusion, drug resistance and recurrence CSCs
    • Nagler C, Zänker KS, Dittmar T. Cell fusion, drug resistance and recurrence CSCs. Adv Exp Med Biol 2011; 714: 173-182.
    • (2011) Adv Exp Med Biol , vol.714 , pp. 173-182
    • Nagler, C.1    Zänker, K.S.2    Dittmar, T.3
  • 58
    • 79951825045 scopus 로고    scopus 로고
    • Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming
    • Powell AE, Anderson EC, Davies PS, Silk AD, Pelz C, Impey S, Wong MH. Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming. Cancer Res 2011; 71: 1497-1505.
    • (2011) Cancer Res , vol.71 , pp. 1497-1505
    • Powell, A.E.1    Anderson, E.C.2    Davies, P.S.3    Silk, A.D.4    Pelz, C.5    Impey, S.6    Wong, M.H.7
  • 59
    • 84858608410 scopus 로고    scopus 로고
    • Cancer stem cells: Impact, heterogeneity, and uncertainty
    • Magee JA, Piskounova E, Morrison SJ. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 2012; 21: 283-296.
    • (2012) Cancer Cell , vol.21 , pp. 283-296
    • Magee, J.A.1    Piskounova, E.2    Morrison, S.J.3
  • 61
    • 84859080133 scopus 로고    scopus 로고
    • Cáncer de próstata y apoptosis
    • Mayora A, Arvelo F. Cáncer de próstata y apoptosis. Invest Clín 2011; 52: 376-396.
    • (2011) Invest Clín , vol.52 , pp. 376-396
    • Mayora, A.1    Arvelo, F.2
  • 62
    • 33847047461 scopus 로고    scopus 로고
    • Epigenetics: A landscape takes shape
    • Goldberg AD, Allis CD, Bernstein E. Epigenetics: a landscape takes shape. Cell 2007; 128: 635-638.
    • (2007) Cell , vol.128 , pp. 635-638
    • Goldberg, A.D.1    Allis, C.D.2    Bernstein, E.3
  • 65
    • 84873160542 scopus 로고    scopus 로고
    • Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells
    • Mimeault M, Batra SK. Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells. J Cell Mol Med 2013; 17: 30-54.
    • (2013) J Cell Mol Med , vol.17 , pp. 30-54
    • Mimeault, M.1    Batra, S.K.2
  • 67
    • 39449106321 scopus 로고    scopus 로고
    • Persistence of CD133+ cells in human and mouseglioma cell lines: Detailed characterization of GL261 glioma cells withcancer stem cell-like properties
    • Wu A, Oh S, Wiesner SM, Ericson K, Chen L, Hall WA, Champoux PE, Low WC, Ohlfest JR. Persistence of CD133+ cells in human and mouseglioma cell lines: detailed characterization of GL261 glioma cells withcancer stem cell-like properties. Stem Cells Dev 2008; 17: 173-184.
    • (2008) Stem Cells Dev , vol.17 , pp. 173-184
    • Wu, A.1    Oh, S.2    Wiesner, S.M.3    Ericson, K.4    Chen, L.5    Hall, W.A.6    Champoux, P.E.7    Low, W.C.8    Ohlfest, J.R.9
  • 68
    • 79951780026 scopus 로고    scopus 로고
    • Notch signaling contributes to the maintenance of both normal neural stem cells and patient- derived glioma stem cells
    • Hu YY, Zheng MH, Cheng G, Li L, Liang L, Gao F, Wei YN, Fu LA, Han H. Notch signaling contributes to the maintenance of both normal neural stem cells and patient- derived glioma stem cells. BMC Cancer 2011; 11:1-13.
    • (2011) BMC Cancer , vol.11 , pp. 1-13
    • Hu, Y.Y.1    Zheng, M.H.2    Cheng, G.3    Li, L.4    Liang, L.5    Gao, F.6    Wei, Y.N.7    Fu, L.A.8    Han, H.9
  • 69
    • 77956926560 scopus 로고    scopus 로고
    • Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal
    • Aguirre A, Rubio ME, Gallo V. Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal. Nature 2010; 467: 323-327.
    • (2010) Nature , vol.467 , pp. 323-327
    • Aguirre, A.1    Rubio, M.E.2    Gallo, V.3
  • 73
    • 0036860704 scopus 로고    scopus 로고
    • The Wnt signalling pathway
    • Huelsken J, Behrens J. The Wnt signalling pathway. J Cell Sci 2002; 115:3977- 3978.
    • (2002) J Cell Sci , vol.115 , pp. 3977-3978
    • Huelsken, J.1    Behrens, J.2
  • 74
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T, Clevers H. Wnt signalling in stem cells and cancer. Nature 2005; 434: 843- 850.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 75
    • 84862170024 scopus 로고    scopus 로고
    • Drugging Wnt signalling in cancer
    • Polakis P. Drugging Wnt signalling in cancer. EMBO J 2012; 31:2737-2746.
    • (2012) EMBO J , vol.31 , pp. 2737-2746
    • Polakis, P.1
  • 77
    • 34547095240 scopus 로고    scopus 로고
    • Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma
    • Shiras A, Chettiar ST, Shepal V, Rajendran G, Prasad GR, Shastry P. Spontaneous transformation of human adult nontumorigenic stem cells to cancer stem cells is driven by genomic instability in a human model of glioblastoma. Stem Cells 2007; 25: 1478-1489.
    • (2007) Stem Cells , vol.25 , pp. 1478-1489
    • Shiras, A.1    Chettiar, S.T.2    Shepal, V.3    Rajendran, G.4    Prasad, G.R.5    Shastry, P.6
  • 78
    • 84859778293 scopus 로고    scopus 로고
    • mTOR signaling in growth control and disease
    • Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell 2012; 149: 274-293.
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 79
    • 82555167017 scopus 로고    scopus 로고
    • Signaling circuitries controlling stem cell fate: To be or not to be
    • Iglesias-Bartolome R, Gutkind JS. Signaling circuitries controlling stem cell fate: to be or not to be. Curr Opin Cell Biol 2011; 23:716-723.
    • (2011) Curr Opin Cell Biol , vol.23 , pp. 716-723
    • Iglesias-Bartolome, R.1    Gutkind, J.S.2
  • 80
    • 70449394784 scopus 로고    scopus 로고
    • The rapamycin-regulated gene expression signature determines prognosis for breast cancer
    • Akcakanat A, Zhang L, Tsavachidis S, Meric-Bernstam F. The rapamycin-regulated gene expression signature determines prognosis for breast cancer. Mol Cancer 2009; 8:1-11.
    • (2009) Mol Cancer , vol.8 , pp. 1-11
    • Akcakanat, A.1    Zhang, L.2    Tsavachidis, S.3    Meric-Bernstam, F.4
  • 81
    • 39449135834 scopus 로고    scopus 로고
    • PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
    • Hambardzumyan D, Becher OJ, Rosenblum MK, Pandolfi PP, Manova- Todorova K, Holland EC. PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. Genes Dev 2008; 22: 436-448.
    • (2008) Genes Dev , vol.22 , pp. 436-448
    • Hambardzumyan, D.1    Becher, O.J.2    Rosenblum, M.K.3    Pandolfi, P.P.4    Manova-Todorova, K.5    Holland, E.C.6
  • 82
    • 77955747346 scopus 로고    scopus 로고
    • With TOR, less is more: A key role for the conserved nutrient-sensing TOR pathway in aging
    • Kapahi P, Chen D, Rogers AN, Katewa SD, Li PW, Thomas EL, Kockel L. With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging. Cell Metab 2010;11: 453-65.
    • (2010) Cell Metab , vol.11 , pp. 453-465
    • Kapahi, P.1    Chen, D.2    Rogers, A.N.3    Katewa, S.D.4    Li, P.W.5    Thomas, E.L.6    Kockel, L.7
  • 83
    • 84867897183 scopus 로고    scopus 로고
    • Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin
    • Chong ZZ, Shang YC, Wang S, Maiese K. Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin. Prog Neurobiol 2012; 99: 128-148.
    • (2012) Prog Neurobiol , vol.99 , pp. 128-148
    • Chong, Z.Z.1    Shang, Y.C.2    Wang, S.3    Maiese, K.4
  • 84
    • 84871721552 scopus 로고    scopus 로고
    • mTOR: On target for novel therapeutic strategies in the nervous system
    • Maiese K, Chong ZZ, Shang YC, Wang S. mTOR: on target for novel therapeutic strategies in the nervous system. Trends Mol Med 2013; 19:51-60.
    • (2013) Trends Mol Med , vol.19 , pp. 51-60
    • Maiese, K.1    Chong, Z.Z.2    Shang, Y.C.3    Wang, S.4
  • 85
    • 79960761944 scopus 로고    scopus 로고
    • An emerging role for TOR signaling in mammalian tissue and stem cell physiology
    • Russell RC, Fang C, Guan KL. An emerging role for TOR signaling in mammalian tissue and stem cell physiology. Development 2011; 138: 3343-3356.
    • (2011) Development , vol.138 , pp. 3343-3356
    • Russell, R.C.1    Fang, C.2    Guan, K.L.3
  • 86
    • 84855252105 scopus 로고    scopus 로고
    • A simplified and modified procedure to culture brain glioma stem cells from clinical specimens
    • Qiu B, Zhang D, Tao J, Wu A, Wang Y. A simplified and modified procedure to culture brain glioma stem cells from clinical specimens. Oncol Lett 2012; 3: 50-54.
    • (2012) Oncol Lett , vol.3 , pp. 50-54
    • Qiu, B.1    Zhang, D.2    Tao, J.3    Wu, A.4    Wang, Y.5
  • 87
    • 79952318891 scopus 로고    scopus 로고
    • Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer
    • Song Z, Yue W, Wei B, Wang N, Li T, Guan L, Shi S, Zeng Q, Pei X, Chen L. Sonic hedgehog pathway is essential for maintenance of cancer stem-like cells in human gastric cancer. PLoS One 2011; 6: 1-13.
    • (2011) PLoS One , vol.6 , pp. 1-13
    • Song, Z.1    Yue, W.2    Wei, B.3    Wang, N.4    Li, T.5    Guan, L.6    Shi, S.7    Zeng, Q.8    Pei, X.9    Chen, L.10
  • 89
    • 73149105708 scopus 로고    scopus 로고
    • Role of sonic hedgehog signaling and the expression of its components in human embryonic stem cells
    • Wu SM, Choo AB, Yap MG, Chan KK. Role of sonic hedgehog signaling and the expression of its components in human embryonic stem cells. Stem Cell Res 2010; 4: 38-49.
    • (2010) Stem Cell Res , vol.4 , pp. 38-49
    • Wu, S.M.1    Choo, A.B.2    Yap, M.G.3    Chan, K.K.4
  • 90
    • 33846237601 scopus 로고    scopus 로고
    • HEDGEHOG- GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
    • Clement V, Sanchez P, de Tribolet N, Radovanovic I, Ruiz I Altaba A. HEDGEHOG- GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity. Curr Biol 2007; 17: 165-172.
    • (2007) Curr Biol , vol.17 , pp. 165-172
    • Clement, V.1    Sanchez, P.2    de Tribolet, N.3    Radovanovic, I.4    Ruiz I Altaba, A.5
  • 91
    • 33644509505 scopus 로고    scopus 로고
    • Patched1 functions as a gatekeeper by promoting cell cycle progression
    • Adolphe C, Hetherington R, Ellis T, Wainwright B. Patched1 functions as a gatekeeper by promoting cell cycle progression. Cancer Res 2006; 66: 2081-2088.
    • (2006) Cancer Res , vol.66 , pp. 2081-2088
    • Adolphe, C.1    Hetherington, R.2    Ellis, T.3    Wainwright, B.4
  • 92
    • 6344250799 scopus 로고    scopus 로고
    • Voie Patched/Sonic Hedgehog et carcinomes basocellulaires
    • Basset-Seguin N, Soufir N. Voie Patched/Sonic Hedgehog et carcinomes basocellulaires. Med Sci (Paris) 2004; 20: 899-903.
    • (2004) Med Sci (Paris) , vol.20 , pp. 899-903
    • Basset-Seguin, N.1    Soufir, N.2
  • 93
    • 82555185376 scopus 로고    scopus 로고
    • The epidermal growth factor receptor/ Erb-B/HER family in normal and malignant breast biology
    • Eccles SA. The epidermal growth factor receptor/ Erb-B/HER family in normal and malignant breast biology. Int J Dev Biol 2011; 55: 685-696.
    • (2011) Int J Dev Biol , vol.55 , pp. 685-696
    • Eccles, S.A.1
  • 97
    • 58149380742 scopus 로고    scopus 로고
    • Stem cell concepts renew cancer research
    • Dick JE. Stem cell concepts renew cancer research. Blood 2008; 112: 4793-4807.
    • (2008) Blood , vol.112 , pp. 4793-4807
    • Dick, J.E.1
  • 98
    • 84892569943 scopus 로고    scopus 로고
    • Molecular characterization and clinical implications of spindle cells in nasopharyngeal carcinoma: A novel molecule- morphology model of tumor progression proposed
    • Luo W, Yao K. Molecular characterization and clinical implications of spindle cells in nasopharyngeal carcinoma: a novel molecule- morphology model of tumor progression proposed. PLoS One 2013; 8: 1-12.
    • (2013) PLoS One , vol.8 , pp. 1-12
    • Luo, W.1    Yao, K.2
  • 99
    • 0037227099 scopus 로고    scopus 로고
    • Multipotentcell lineages in early mouse development depend on SOX2 function
    • Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N. Multipotentcell lineages in early mouse development depend on SOX2 function. Genes Dev 2003; 17: 126-140.
    • (2003) Genes Dev , vol.17 , pp. 126-140
    • Avilion, A.A.1    Nicolis, S.K.2    Pevny, L.H.3    Perez, L.4    Vivian, N.5
  • 100
    • 0034895829 scopus 로고    scopus 로고
    • Oct-4 gatekeeper in the beginnings of mammalian development
    • Pesce M, Schöler HR. Oct-4 gatekeeper in the beginnings of mammalian development. Stem Cells 2001; 19:271-278.
    • (2001) Stem Cells , vol.19 , pp. 271-278
    • Pesce, M.1    Schöler, H.R.2
  • 101
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113: 631-642.
    • (2003) Cell , vol.113 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5
  • 102
    • 0033649166 scopus 로고    scopus 로고
    • Resistencia multidroga (MDR) o pleiotropica
    • Arvelo F, Merentes E, Cotte C. Resistencia multidroga (MDR) o pleiotropica. Acta Cient Venez 2000; 51: 45-52.
    • (2000) Acta Cient Venez , vol.51 , pp. 45-52
    • Arvelo, F.1    Merentes, E.2    Cotte, C.3
  • 104
    • 84857052013 scopus 로고    scopus 로고
    • Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression
    • Krantz SB, Shields MA, Dangi-Garimella S, Munshi HG, Bentrem DJ. Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression. J Surg Res 2012; 173: 105- 112.
    • (2012) J Surg Res , vol.173 , pp. 105-112
    • Krantz, S.B.1    Shields, M.A.2    Dangi-Garimella, S.3    Munshi, H.G.4    Bentrem, D.J.5
  • 106
    • 78149243774 scopus 로고    scopus 로고
    • Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation
    • Louie E, Nik S, Chen JS, Schmidt M, Song B, Pacson C, Chen XF, Park S, Ju J, Chen EI. Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation. Breast Cancer Res 2010; 12: R94.
    • (2010) Breast Cancer Res , vol.12
    • Louie, E.1    Nik, S.2    Chen, J.S.3    Schmidt, M.4    Song, B.5    Pacson, C.6    Chen, X.F.7    Park, S.8    Ju, J.9    Chen, E.I.10
  • 107
    • 84873160542 scopus 로고    scopus 로고
    • Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells
    • Mimeault M, Batra SK. Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells. J Cell Mol Med 2013; 17: 30-54.
    • (2013) J Cell Mol Med , vol.17 , pp. 30-54
    • Mimeault, M.1    Batra, S.K.2
  • 109
    • 33745762804 scopus 로고    scopus 로고
    • Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells
    • Shinin V, Gayraud-Morel B, Gomès D, Tajbakhsh S. Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nat Cell Biol 2006; 8: 677-687.
    • (2006) Nat Cell Biol , vol.8 , pp. 677-687
    • Shinin, V.1    Gayraud-Morel, B.2    Gomès, D.3    Tajbakhsh, S.4
  • 110
    • 84866432417 scopus 로고    scopus 로고
    • Beyond ABC: Another mechanism of drug resistance in melanoma side population
    • Fukunaga-Kalabis M, Herlyn M. Beyond ABC: another mechanism of drug resistance in melanoma side population. J Invest Dermatol 2012; 132: 2317-2319.
    • (2012) J Invest Dermatol , vol.132 , pp. 2317-2319
    • Fukunaga-Kalabis, M.1    Herlyn, M.2
  • 112
    • 84858002750 scopus 로고    scopus 로고
    • Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance
    • Natarajan K, Xie Y, Baer MR, Ross DD. Role of breast cancer resistance protein (BCRP/ABCG2) in cancer drug resistance. Biochem Pharmacol 2012; 83: 1084-1103.
    • (2012) Biochem Pharmacol , vol.83 , pp. 1084-1103
    • Natarajan, K.1    Xie, Y.2    Baer, M.R.3    Ross, D.D.4
  • 118
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2002; 2: 647-656.
    • (2002) Nat Rev Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 120
    • 84877057303 scopus 로고    scopus 로고
    • Mechanisms of chemoresistance in cancer stem cells
    • Abdullah LN, Chow EK. Mechanisms of chemoresistance in cancer stem cells. Clin Transl Med 2013; 2: 1-9.
    • (2013) Clin Transl Med , vol.2 , pp. 1-9
    • Abdullah, L.N.1    Chow, E.K.2
  • 121
    • 66249139555 scopus 로고    scopus 로고
    • CD44+ cáncer cells express higher levels of the anti-apoptotic protein Bcl-2 in breast tumours
    • Madjd Z, Mehrjerdi A, Sharif A, Molanei S, Shahzadi S, Asadi-Lari M. CD44+ cáncer cells express higher levels of the anti-apoptotic protein Bcl-2 in breast tumours, Cancer Immun 2009; 9:1-7.
    • (2009) Cancer Immun , vol.9 , pp. 1-7
    • Madjd, Z.1    Mehrjerdi, A.2    Sharif, A.3    Molanei, S.4    Shahzadi, S.5    Asadi-Lari, M.6
  • 122
    • 84873157525 scopus 로고    scopus 로고
    • Intrinsic radiation resistance of mesenchymal cancer stem cells and implications for treatment response in a murine sarcoma model
    • D'Andrea FP. Intrinsic radiation resistance of mesenchymal cancer stem cells and implications for treatment response in a murine sarcoma model. Dan Med J 2012; 59: B4388.
    • (2012) Dan Med J , vol.59
    • D'Andrea, F.P.1
  • 124
  • 125
    • 77953384917 scopus 로고    scopus 로고
    • Redox regulation in cancer: A doubleedged sword with therapeutic potential
    • Acharya A, Das I, Chandhok D, Saha T. Redox regulation in cancer: a doubleedged sword with therapeutic potential. Oxid Med Cell Longev 2010; 3: 23-34.
    • (2010) Oxid Med Cell Longev , vol.3 , pp. 23-34
    • Acharya, A.1    Das, I.2    Chandhok, D.3    Saha, T.4
  • 126
    • 82155171284 scopus 로고    scopus 로고
    • Regulation of reactive oxygen species in stem cells and cancer stem cells
    • Kobayashi CI, Suda T. Regulation of reactive oxygen species in stem cells and cancer stem cells. J Cell Physiol 2012; 227: 421-430.
    • (2012) J Cell Physiol , vol.227 , pp. 421-430
    • Kobayashi, C.I.1    Suda, T.2
  • 127
    • 0030024868 scopus 로고    scopus 로고
    • Induction of cyclophosphamide-resistance by aldehyde- dehydrogenase gene transfer
    • Magni M, Shammah S, Schiró R, Mellado W, Dalla-Favera R, Gianni AM. Induction of cyclophosphamide-resistance by aldehyde- dehydrogenase gene transfer. Blood 1996; 87: 1097-1103.
    • (1996) Blood , vol.87 , pp. 1097-1103
    • Magni, M.1    Shammah, S.2    Schiró, R.3    Mellado, W.4    Dalla-Favera, R.5    Gianni, A.M.6
  • 128
    • 0021722034 scopus 로고
    • Role of aldehyde dehydrogenase in cyclophosphamide-resistant L 1210 leukemia
    • Hilton J. Role of aldehyde dehydrogenase in cyclophosphamide-resistant L 1210 leukemia. Cancer Res 1984; 5: 5156-5160.
    • (1984) Cancer Res , vol.5 , pp. 5156-5160
    • Hilton, J.1
  • 133
    • 40749150740 scopus 로고    scopus 로고
    • CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway
    • Ma S, Lee TK, Zheng BJ, Chan KW, Guan XY. CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway. Oncogene 2008; 27:1749-1758.
    • (2008) Oncogene , vol.27 , pp. 1749-1758
    • Ma, S.1    Lee, T.K.2    Zheng, B.J.3    Chan, K.W.4    Guan, X.Y.5
  • 135
    • 77949737190 scopus 로고    scopus 로고
    • Hipoxia en la malignidad del cáncer
    • Arvelo F, Cotte C. Hipoxia en la malignidad del cáncer. Invest Clín 2009; 50: 529-546.
    • (2009) Invest Clín , vol.50 , pp. 529-546
    • Arvelo, F.1    Cotte, C.2
  • 136
    • 77958498222 scopus 로고    scopus 로고
    • The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer
    • Smith J, Tho LM, Xu N, Gillespie DA. The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. Adv Cancer Res 2010; 108: 73-112.
    • (2010) Adv Cancer Res , vol.108 , pp. 73-112
    • Smith, J.1    Tho, L.M.2    Xu, N.3    Gillespie, D.A.4
  • 137
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, Mclendon R, Hao Y, Shi Q, Hjelmeland A, Dewhirst M, Bigner D, Rich J. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006; 444: 756-760.
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.6    Dewhirst, M.7    Bigner, D.8    Rich, J.9
  • 138
    • 79953013766 scopus 로고    scopus 로고
    • Inhibition of ataxia telangiectasia and Rad 3 related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor initiating cell fraction
    • Gallmeler E, Hermann P, Muelle M, Machado J, Ziesch A, De Toni E, Palagyi A, Eisen C, Ellwart J, Rivera J. Inhibition of ataxia telangiectasia and Rad 3 related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor initiating cell fraction. Stem Cells 2011; 29: 418-429.
    • (2011) Stem Cells , vol.29 , pp. 418-429
    • Gallmeler, E.1    Hermann, P.2    Muelle, M.3    Machado, J.4    Ziesch, A.5    De Toni, E.6    Palagyi, A.7    Eisen, C.8    Ellwart, J.9    Rivera, J.10
  • 139
    • 34247217230 scopus 로고    scopus 로고
    • Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin
    • Yates CC, Shepard CR, Stolz DB, Wells A. Co-culturing human prostate carcinoma cells with hepatocytes leads to increased expression of E-cadherin. Br J Cancer 2007; 96: 1246-1252.
    • (2007) Br J Cancer , vol.96 , pp. 1246-1252
    • Yates, C.C.1    Shepard, C.R.2    Stolz, D.B.3    Wells, A.4
  • 140
    • 34250705694 scopus 로고    scopus 로고
    • A human three-dimensional cell line model allows the study of dynamic and reversible epithelial-mesenchymal and mesenchymal-epithelial transition that underpins colorectal carcinogenesis
    • Vincan E, Brabletz T, Faux MC, Ramsay RG. A human three-dimensional cell line model allows the study of dynamic and reversible epithelial-mesenchymal and mesenchymal-epithelial transition that underpins colorectal carcinogenesis. Cells Tissues Organs 2007; 185: 20-28.
    • (2007) Cells Tissues Organs , vol.185 , pp. 20-28
    • Vincan, E.1    Brabletz, T.2    Faux, M.C.3    Ramsay, R.G.4
  • 141
    • 77954304397 scopus 로고    scopus 로고
    • Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition
    • Chao YL, Shepard CR, Wells A. Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition. Mol Cancer 2010; 9: 1-18.
    • (2010) Mol Cancer , vol.9 , pp. 1-18
    • Chao, Y.L.1    Shepard, C.R.2    Wells, A.3
  • 142
    • 84861527239 scopus 로고    scopus 로고
    • To differentiate or not routes towards metástasis
    • Brabletz T. To differentiate or not routes towards metástasis. Nat Rev Cancer 2012; 12: 425-436.
    • (2012) Nat Rev Cancer , vol.12 , pp. 425-436
    • Brabletz, T.1
  • 143
    • 70349729970 scopus 로고    scopus 로고
    • Epithelialmesenchymal transition and cell cooperativity in metastasis
    • Tsuji T, Ibaragi S, Hu GF. Epithelialmesenchymal transition and cell cooperativity in metastasis. Cancer Res 2009; 69: 7135-7139.
    • (2009) Cancer Res , vol.69 , pp. 7135-7139
    • Tsuji, T.1    Ibaragi, S.2    Hu, G.F.3
  • 145
    • 84873160542 scopus 로고    scopus 로고
    • Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells
    • Mimeault M, Batra SK. Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells. J Cell Mol Med 2013; 17: 30-54.
    • (2013) J Cell Mol Med , vol.17 , pp. 30-54
    • Mimeault, M.1    Batra, S.K.2


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