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Volumn 20, Issue 10, 2004, Pages 899-903

Patched/Sonic Hedgehog pathway and basal cell carcinoma;Voie Patched/Sonic Hedgehog et carcinomes basocellulaires

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR FKHR;

EID: 6344250799     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20042010899     Document Type: Review
Times cited : (8)

References (38)
  • 1
    • 9344255432 scopus 로고    scopus 로고
    • The multicentre south European study «Helios». II. Different sun exposure patterns in the aetiology of basal cell and squamous cell carcinomas of the skin
    • Rosso S, Zanetti R, Martinez C, et al. The multicentre south European study «Helios». II. Different sun exposure patterns in the aetiology of basal cell and squamous cell carcinomas of the skin. Br J Cancer 1996 ; 73 : 1447-54.
    • (1996) Br J Cancer , vol.73 , pp. 1447-1454
    • Rosso, S.1    Zanetti, R.2    Martinez, C.3
  • 2
    • 15844386165 scopus 로고    scopus 로고
    • Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome
    • Hahn H, Wicking C, Zaphiropoulous PG, et al. Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 1996 ; 85 : 841-51.
    • (1996) Cell , vol.85 , pp. 841-851
    • Hahn, H.1    Wicking, C.2    Zaphiropoulous, P.G.3
  • 3
    • 15844381336 scopus 로고    scopus 로고
    • Human homolog of patched, a candidate gene for the basal cell nevus syndrome
    • Johnson RL, Rothman AL, Xie J, et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996 ; 272 : 1668-71.
    • (1996) Science , vol.272 , pp. 1668-1671
    • Johnson, R.L.1    Rothman, A.L.2    Xie, J.3
  • 4
    • 0027997542 scopus 로고
    • Delineation of two distinct deleted regions on chromosome 9 in human non-melanoma skin cancers
    • Quinn AG, Sikkink S, Rees J. Delineation of two distinct deleted regions on chromosome 9 in human non-melanoma skin cancers. Genes Chrom Cancer 1994 ; 11 : 222-5.
    • (1994) Genes Chrom Cancer , vol.11 , pp. 222-225
    • Quinn, A.G.1    Sikkink, S.2    Rees, J.3
  • 5
    • 0035658059 scopus 로고    scopus 로고
    • Nonrandom karyotypic features in basal cell carcinomas of the skin
    • Jin Y, Martins C, Salemark L, et al. Nonrandom karyotypic features in basal cell carcinomas of the skin. Cancer Genet Cytogenet 2001 ; 131 : 109-19.
    • (2001) Cancer Genet Cytogenet , vol.131 , pp. 109-119
    • Jin, Y.1    Martins, C.2    Salemark, L.3
  • 6
  • 7
    • 0029912403 scopus 로고    scopus 로고
    • Characterization of p53 gene mutations in basal-cell carcinomas: Comparison between sun-exposed and less-exposed skin areas
    • Matsumura Y, Nishigori C, Yagi T, et al. Characterization of p53 gene mutations in basal-cell carcinomas: Comparison between sun-exposed and less-exposed skin areas. Int J Cancer 1996 ; 65 : 778-80.
    • (1996) Int J Cancer , vol.65 , pp. 778-780
    • Matsumura, Y.1    Nishigori, C.2    Yagi, T.3
  • 8
    • 0035054358 scopus 로고    scopus 로고
    • The Hedgehog pathway and basal cell carcinomas
    • Bale AE, Yu KP. The Hedgehog pathway and basal cell carcinomas. Hum Mol Genet 2001 ; 10 : 757-62.
    • (2001) Hum Mol Genet , vol.10 , pp. 757-762
    • Bale, A.E.1    Yu, K.P.2
  • 9
    • 0032898184 scopus 로고    scopus 로고
    • Isolation and characterization of human Patched 2 (PTCH2), a putative tumour suppressor gene, in basal cell carcinoma and medulloblastoma on chromosome Ip32
    • Smyth I, Narang MA, Evans T, et al. Isolation and characterization of human Patched 2 (PTCH2), a putative tumour suppressor gene, in basal cell carcinoma and medulloblastoma on chromosome Ip32. Hum Mol Genet 1999 ; 8 : 291-7.
    • (1999) Hum Mol Genet , vol.8 , pp. 291-297
    • Smyth, I.1    Narang, M.A.2    Evans, T.3
  • 10
    • 0032482964 scopus 로고    scopus 로고
    • The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a Patched-related gene, TRC8
    • Gemmill RM, West JD, Boldog F, et al. The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a Patched-related gene, TRC8. Proc Natl Acad Sci USA 1998 ; 95 : 9572-7.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9572-9577
    • Gemmill, R.M.1    West, J.D.2    Boldog, F.3
  • 11
    • 0029784223 scopus 로고    scopus 로고
    • Smoothened encodes a receptor-like serpentine protein required for Hedgehog signalling
    • Van den Heuvel M, Ingham PW. Smoothened encodes a receptor-like serpentine protein required for Hedgehog signalling. Nature 1996 ; 382 : 547-51.
    • (1996) Nature , vol.382 , pp. 547-551
    • Van Den Heuvel, M.1    Ingham, P.W.2
  • 12
    • 12944272018 scopus 로고    scopus 로고
    • Receptor-mediated endocytosis of soluble and membrane-tethered Sonic Hedgehog by Patched-1
    • Incardona JP, Lee JH, Robertson CP, et al. Receptor-mediated endocytosis of soluble and membrane-tethered Sonic Hedgehog by Patched-1. Proc Natl Acad Sci USA 2000 ; 97 : 12044-9.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 12044-12049
    • Incardona, J.P.1    Lee, J.H.2    Robertson, C.P.3
  • 13
    • 0034682719 scopus 로고    scopus 로고
    • Hedgehog induces opposite changes in turnover and subcellular localization of Patched and Smoothened
    • Denef N, Neubuser D, Perez L, Cohen SM. Hedgehog induces opposite changes in turnover and subcellular localization of Patched and Smoothened. Cell 2000 ; 102 : 521-31.
    • (2000) Cell , vol.102 , pp. 521-531
    • Denef, N.1    Neubuser, D.2    Perez, L.3    Cohen, S.M.4
  • 14
    • 0037158748 scopus 로고    scopus 로고
    • Patched acts catalytically to suppress the activity of Smoothened
    • Taipale J, Cooper MK, Maiti T, Beachy PA. Patched acts catalytically to suppress the activity of Smoothened. Nature 2002 ; 418 : 892-7.
    • (2002) Nature , vol.418 , pp. 892-897
    • Taipale, J.1    Cooper, M.K.2    Maiti, T.3    Beachy, P.A.4
  • 16
    • 0031002840 scopus 로고    scopus 로고
    • Clinical manifestation in 105 persons with nevoid basal cell carcinoma syndrome
    • Kimonis VE, Goldsetin AM, Pastakia B, et al. Clinical manifestation in 105 persons with nevoid basal cell carcinoma syndrome. Am J Med Genet 1997 ; 69 : 299-308.
    • (1997) Am J Med Genet , vol.69 , pp. 299-308
    • Kimonis, V.E.1    Goldsetin, A.M.2    Pastakia, B.3
  • 17
    • 0033711384 scopus 로고    scopus 로고
    • Hedgehog signalling in cancer
    • Toftgard R. Hedgehog signalling in cancer. Cell Mol Life Sci 2000 ; 57 : 1720-31.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 1720-1731
    • Toftgard, R.1
  • 18
    • 16044363842 scopus 로고    scopus 로고
    • The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas
    • Gailani MR, Stahle-Backdahl M, Leffell DJ, et al. The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas. Nat Genet 1996 ; 14 : 78-81.
    • (1996) Nat Genet , vol.14 , pp. 78-81
    • Gailani, M.R.1    Stahle-Backdahl, M.2    Leffell, D.J.3
  • 19
    • 0031837549 scopus 로고    scopus 로고
    • Identification of mutations in the human Patched gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome
    • Aszterbaum M, Rothman A, Johnson RL, et al. Identification of mutations in the human Patched gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome. J Invest Dermatol 1998 ; 110 : 885-8.
    • (1998) J Invest Dermatol , vol.110 , pp. 885-888
    • Aszterbaum, M.1    Rothman, A.2    Johnson, R.L.3
  • 20
    • 0029841366 scopus 로고    scopus 로고
    • Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: Different in vivo mechanisms of PTCH inactivation
    • Unden AB, Holmberg E, Lundh-Rozell B, et al. Mutations in the human homologue of Drosophila patched (PTCH) in basal cell carcinomas and the Gorlin syndrome: different in vivo mechanisms of PTCH inactivation. Cancer Res 1996 ; 56 : 4562-5.
    • (1996) Cancer Res , vol.56 , pp. 4562-4565
    • Unden, A.B.1    Holmberg, E.2    Lundh-Rozell, B.3
  • 21
    • 0035935999 scopus 로고    scopus 로고
    • Patched and p53 gene alterations in sporadic and hereditary basal cell cancer
    • Ling G, Ahmadian A, Persson A, et al. Patched and p53 gene alterations in sporadic and hereditary basal cell cancer. Oncogene 2001 ; 20 : 7770-8.
    • (2001) Oncogene , vol.20 , pp. 7770-7778
    • Ling, G.1    Ahmadian, A.2    Persson, A.3
  • 22
    • 0031913524 scopus 로고    scopus 로고
    • Activating Smoothened mutations in sporadic basal-cell carcinoma
    • Xie J, Murone M, Luoh SM, et al. Activating Smoothened mutations in sporadic basal-cell carcinoma. Nature 1998 ; 391 ; 90-2.
    • (1998) Nature , vol.391 , pp. 90-92
    • Xie, J.1    Murone, M.2    Luoh, S.M.3
  • 23
    • 0030955557 scopus 로고    scopus 로고
    • Basal cell carcinomas in mice overexpressing Sonic Hedgehog
    • Oro AE, Higgins KM, Hu Z, et al. Basal cell carcinomas in mice overexpressing Sonic Hedgehog. Science 1997 ; 276 : 817-21.
    • (1997) Science , vol.276 , pp. 817-821
    • Oro, A.E.1    Higgins, K.M.2    Hu, Z.3
  • 24
    • 0032568040 scopus 로고    scopus 로고
    • No evidence for the H133Y mutation in Sonic Hedgehog in a collection of common tumour types
    • Wicking C, Evans T, Henk B, et al. No evidence for the H133Y mutation in Sonic Hedgehog in a collection of common tumour types. Oncogene 1998 ; 16 : 1091-3.
    • (1998) Oncogene , vol.16 , pp. 1091-1093
    • Wicking, C.1    Evans, T.2    Henk, B.3
  • 25
    • 0035979147 scopus 로고    scopus 로고
    • A role of PDGFRα in basal cell carcinoma proliferation
    • Xie J, Aszterbaum M, Zhang X, et al. A role of PDGFRα in basal cell carcinoma proliferation. Proc Natl Acad Sci USA 2001 ; 98 : 9255-9.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9255-9259
    • Xie, J.1    Aszterbaum, M.2    Zhang, X.3
  • 26
    • 17344379513 scopus 로고    scopus 로고
    • Five years on the wings of fork head
    • Kaufman E, Knochel W. Five years on the wings of fork head. Mech Dev 2001 ; 57 : 3-20.
    • (2001) Mech Dev , vol.57 , pp. 3-20
    • Kaufman, E.1    Knochel, W.2
  • 27
    • 0037102232 scopus 로고    scopus 로고
    • FOXM1 is a downstream target of Gli1 in basal cell carcinomas
    • Teh MT, Wong ST, Neill GW, et al. FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Res 2002 ; 62 : 4773-80.
    • (2002) Cancer Res , vol.62 , pp. 4773-4780
    • Teh, M.T.1    Wong, S.T.2    Neill, G.W.3
  • 28
    • 0030802458 scopus 로고    scopus 로고
    • Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog
    • Fan H, Oro AE, Scott MP, Khavari PA. Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nat Med 1997 ; 3 : 788-92.
    • (1997) Nat Med , vol.3 , pp. 788-792
    • Fan, H.1    Oro, A.E.2    Scott, M.P.3    Khavari, P.A.4
  • 29
    • 0031837454 scopus 로고
    • Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome
    • Hahn H, Wojnowski L, Zimmer AM, et al. Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome. Nat Med 1198 ; 4 : 619-22.
    • (1198) Nat Med , vol.4 , pp. 619-622
    • Hahn, H.1    Wojnowski, L.2    Zimmer, A.M.3
  • 30
    • 0032694528 scopus 로고    scopus 로고
    • Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice
    • Aszterbaum M, Epstein J, Oro A, et al. Ultraviolet and ionizing radiation enhance the growth of BCCs and trichoblastomas in patched heterozygous knockout mice. Nat Med 1999 ; 5 : 1285-91.
    • (1999) Nat Med , vol.5 , pp. 1285-1291
    • Aszterbaum, M.1    Epstein, J.2    Oro, A.3
  • 31
    • 0034091805 scopus 로고    scopus 로고
    • Basal cell carcinomas in mice overexpressing Gli2 in skin
    • Grachtchouk M, Mo R, Yu S, et al. Basal cell carcinomas in mice overexpressing Gli2 in skin. Nat Genet 2000 ; 24 : 216-7.
    • (2000) Nat Genet , vol.24 , pp. 216-217
    • Grachtchouk, M.1    Mo, R.2    Yu, S.3
  • 32
    • 0034724219 scopus 로고    scopus 로고
    • Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1
    • Nilsson M, Unden AB, Krause D, et al. Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1. Proc Natl Acad Sci USA 2000 ; 97 : 3438-43.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3438-3443
    • Nilsson, M.1    Unden, A.B.2    Krause, D.3
  • 33
    • 0032848136 scopus 로고    scopus 로고
    • Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling
    • Sasaki H, Nishizaki Y, Hui C, et al. Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development 1999 ; 126 : 3915-24.
    • (1999) Development , vol.126 , pp. 3915-3924
    • Sasaki, H.1    Nishizaki, Y.2    Hui, C.3
  • 34
    • 0014245807 scopus 로고
    • Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related compounds from other sources
    • Keeler RF, Binns W. Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related compounds from other sources. Teratology 1968 ; 1 : 5-10.
    • (1968) Teratology , vol.1 , pp. 5-10
    • Keeler, R.F.1    Binns, W.2
  • 35
    • 0031723219 scopus 로고    scopus 로고
    • The teratogenic Veratrum alkaloid cyclopamine inhibits Sonic Hedgehog signal transduction
    • Incardona JP, Gaffield W, Kapur RP, Roelink H. The teratogenic Veratrum alkaloid cyclopamine inhibits Sonic Hedgehog signal transduction. Development 1998 ; 125 : 3553-62.
    • (1998) Development , vol.125 , pp. 3553-3562
    • Incardona, J.P.1    Gaffield, W.2    Kapur, R.P.3    Roelink, H.4
  • 36
    • 0034738979 scopus 로고    scopus 로고
    • Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
    • Taipale J, Chen JK, Cooper MK, et al. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature 2000 ; 406 : 1005-9.
    • (2000) Nature , vol.406 , pp. 1005-1009
    • Taipale, J.1    Chen, J.K.2    Cooper, M.K.3
  • 37
    • 0036829397 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
    • Chen JK, Taipale J, Cooper MK, Beachy PA. Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev 2002 ; 16 : 2743-8.
    • (2002) Genes Dev , vol.16 , pp. 2743-2748
    • Chen, J.K.1    Taipale, J.2    Cooper, M.K.3    Beachy, P.A.4
  • 38
    • 0037200078 scopus 로고    scopus 로고
    • Medulloblastoma growth inhibition by Hedgehog pathway blockade
    • Berman DM, Karhadkar SS, Hallahan AR, et al. Medulloblastoma growth inhibition by Hedgehog pathway blockade. Science 2002 ; 297 : 1559-61.
    • (2002) Science , vol.297 , pp. 1559-1561
    • Berman, D.M.1    Karhadkar, S.S.2    Hallahan, A.R.3


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