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Volumn 360, Issue 2, 2015, Pages 89-105

MicroRNAs in colorectal cancer: Small molecules with big functions

Author keywords

Colorectal cancer; MicroRNA; Oncogene; Tumor suppressor

Indexed keywords

CETUXIMAB; MICRORNA; MICRORNA 101; MICRORNA 107; MICRORNA 126; MICRORNA 133; MICRORNA 137; MICRORNA 141; MICRORNA 143; MICRORNA 145; MICRORNA 155; MICRORNA 16; MICRORNA 195; MICRORNA 200; MICRORNA 200B; MICRORNA 200C; MICRORNA 214; MICRORNA 215; MICRORNA 30; MICRORNA 34; MICRORNA 342; MICRORNA 345; MICRORNA 34A; MICRORNA 34B; MICRORNA 34C; MICRORNA 365; MICRORNA 491; PANITUMUMAB; TUMOR MARKER; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84924858306     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.11.051     Document Type: Review
Times cited : (90)

References (189)
  • 1
    • 69549124295 scopus 로고    scopus 로고
    • Pathogenetic and clinical relevance of microRNAs in colorectal cancer
    • Valeri N., Croce C.M., Fabbri M. Pathogenetic and clinical relevance of microRNAs in colorectal cancer. Cancer Genomics Proteomics 2009, 6:195-204.
    • (2009) Cancer Genomics Proteomics , vol.6 , pp. 195-204
    • Valeri, N.1    Croce, C.M.2    Fabbri, M.3
  • 2
    • 54449097149 scopus 로고    scopus 로고
    • A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence
    • Forman J.J., Legesse-Miller A., Coller H.A. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:14879-14884.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 14879-14884
    • Forman, J.J.1    Legesse-Miller, A.2    Coller, H.A.3
  • 3
    • 84858126071 scopus 로고    scopus 로고
    • MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review
    • Iorio M.V., Croce C.M. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol. Med 2012, 4:143-159.
    • (2012) EMBO Mol. Med , vol.4 , pp. 143-159
    • Iorio, M.V.1    Croce, C.M.2
  • 4
    • 84857058409 scopus 로고    scopus 로고
    • Functional relevance of miRNA sequences in human disease
    • Bhayani M.K., Calin G.A., Lai S.Y. Functional relevance of miRNA sequences in human disease. Mutat. Res 2012, 731:14-19.
    • (2012) Mutat. Res , vol.731 , pp. 14-19
    • Bhayani, M.K.1    Calin, G.A.2    Lai, S.Y.3
  • 5
    • 79951979718 scopus 로고    scopus 로고
    • MicroRNAs: master regulators as potential therapeutics in cancer, in: A.K. Cho (Ed.)
    • Garofalo M., Croce C.M. MicroRNAs: master regulators as potential therapeutics in cancer, in: A.K. Cho (Ed.). Ann. Rev. Pharmacol. Toxicol 2011, 51:25-43.
    • (2011) Ann. Rev. Pharmacol. Toxicol , vol.51 , pp. 25-43
    • Garofalo, M.1    Croce, C.M.2
  • 6
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J., Loedige I., Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genetics 2010, 11:597-610.
    • (2010) Nat. Rev. Genetics , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 7
    • 80455123713 scopus 로고    scopus 로고
    • New role of microRNA: carcinogenesis and clinical application in cancer
    • Zhao L.Q., Chen X., Cao Y. New role of microRNA: carcinogenesis and clinical application in cancer. Acta Biochim. Biophys. Sin. (Shanghai) 2011, 43:831-839.
    • (2011) Acta Biochim. Biophys. Sin. (Shanghai) , vol.43 , pp. 831-839
    • Zhao, L.Q.1    Chen, X.2    Cao, Y.3
  • 8
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin G.A., Dumitru C.D., Shimizu M., Bichi R., Zupo S., Noch E., et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:15524-15529.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5    Noch, E.6
  • 9
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L., Teruya-Feldstein J., Weinberg R.A. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007, 449:682-688.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 10
    • 33744521896 scopus 로고    scopus 로고
    • Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines
    • Meng F., Henson R., Lang M., Wehbe H., Maheshwari S., Mendell J.T., et al. Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 2006, 130:2113-2129.
    • (2006) Gastroenterology , vol.130 , pp. 2113-2129
    • Meng, F.1    Henson, R.2    Lang, M.3    Wehbe, H.4    Maheshwari, S.5    Mendell, J.T.6
  • 11
    • 77950809880 scopus 로고    scopus 로고
    • Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells
    • Chen F., Zhu H.H., Zhou L.F., Wu S.S., Wang J., Chen Z. Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells. Oncol. Rep 2010, 23:1457-1462.
    • (2010) Oncol. Rep , vol.23 , pp. 1457-1462
    • Chen, F.1    Zhu, H.H.2    Zhou, L.F.3    Wu, S.S.4    Wang, J.5    Chen, Z.6
  • 12
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
    • Kovalchuk O., Filkowski J., Meservy J., Ilnytskyy Y., Tryndyak V.P., Chekhun V.F., et al. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol. Cancer Ther 2008, 7:2152-2159.
    • (2008) Mol. Cancer Ther , vol.7 , pp. 2152-2159
    • Kovalchuk, O.1    Filkowski, J.2    Meservy, J.3    Ilnytskyy, Y.4    Tryndyak, V.P.5    Chekhun, V.F.6
  • 13
    • 44949249814 scopus 로고    scopus 로고
    • MiR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
    • Xia L., Zhang D., Du R., Pan Y., Zhao L., Sun S., et al. miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int. J. Cancer 2008, 123:372-379.
    • (2008) Int. J. Cancer , vol.123 , pp. 372-379
    • Xia, L.1    Zhang, D.2    Du, R.3    Pan, Y.4    Zhao, L.5    Sun, S.6
  • 14
    • 84855387995 scopus 로고    scopus 로고
    • MicroRNA-365, down-regulated in colon cancer, inhibits cell cycle progression and promotes apoptosis of colon cancer cells by probably targeting cyclin D1 and Bcl-2
    • Nie J., Liu L., Zheng W., Chen L., Wu X., Xu Y.X., et al. MicroRNA-365, down-regulated in colon cancer, inhibits cell cycle progression and promotes apoptosis of colon cancer cells by probably targeting cyclin D1 and Bcl-2. Carcinogenesis 2012, 33:220-225.
    • (2012) Carcinogenesis , vol.33 , pp. 220-225
    • Nie, J.1    Liu, L.2    Zheng, W.3    Chen, L.4    Wu, X.5    Xu, Y.X.6
  • 15
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • Wood L.D., Parsons D.W., Jones S., Lin J., Sjoblom T., Leary R.J., et al. The genomic landscapes of human breast and colorectal cancers. Science 2007, 318:1108-1113.
    • (2007) Science , vol.318 , pp. 1108-1113
    • Wood, L.D.1    Parsons, D.W.2    Jones, S.3    Lin, J.4    Sjoblom, T.5    Leary, R.J.6
  • 17
    • 66749160812 scopus 로고    scopus 로고
    • The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras
    • Tsang W.P., Kwok T.T. The miR-18a* microRNA functions as a potential tumor suppressor by targeting on K-Ras. Carcinogenesis 2009, 30:953-959.
    • (2009) Carcinogenesis , vol.30 , pp. 953-959
    • Tsang, W.P.1    Kwok, T.T.2
  • 19
    • 72849125619 scopus 로고    scopus 로고
    • Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas
    • Mu P., Han Y.C., Betel D., Yao E., Squatrito M., Ogrodowski P., et al. Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas. Genes Dev 2009, 23:2806-2811.
    • (2009) Genes Dev , vol.23 , pp. 2806-2811
    • Mu, P.1    Han, Y.C.2    Betel, D.3    Yao, E.4    Squatrito, M.5    Ogrodowski, P.6
  • 20
    • 84868250570 scopus 로고    scopus 로고
    • Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer
    • Schee K., Boye K., Abrahamsen T.W., Fodstad O., Flatmark K. Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer. BMC Cancer 2012, 12:505.
    • (2012) BMC Cancer , vol.12 , pp. 505
    • Schee, K.1    Boye, K.2    Abrahamsen, T.W.3    Fodstad, O.4    Flatmark, K.5
  • 21
    • 79951881614 scopus 로고    scopus 로고
    • MiR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines
    • Chai H., Liu M., Tian R., Li X., Tang H. miR-20a targets BNIP2 and contributes chemotherapeutic resistance in colorectal adenocarcinoma SW480 and SW620 cell lines. Acta Biochim. Biophys. Sin. (Shanghai) 2011, 43:217-225.
    • (2011) Acta Biochim. Biophys. Sin. (Shanghai) , vol.43 , pp. 217-225
    • Chai, H.1    Liu, M.2    Tian, R.3    Li, X.4    Tang, H.5
  • 22
    • 81855194117 scopus 로고    scopus 로고
    • MiR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer
    • Tsuchida A., Ohno S., Wu W., Borjigin N., Fujita K., Aoki T., et al. miR-92 is a key oncogenic component of the miR-17-92 cluster in colon cancer. Cancer Sci 2011, 102:2264-2271.
    • (2011) Cancer Sci , vol.102 , pp. 2264-2271
    • Tsuchida, A.1    Ohno, S.2    Wu, W.3    Borjigin, N.4    Fujita, K.5    Aoki, T.6
  • 23
    • 33748302836 scopus 로고    scopus 로고
    • Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
    • Dews M., Homayouni A., Yu D., Murphy D., Sevignani C., Wentzel E., et al. Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster. Nat. Genet 2006, 38:1060-1065.
    • (2006) Nat. Genet , vol.38 , pp. 1060-1065
    • Dews, M.1    Homayouni, A.2    Yu, D.3    Murphy, D.4    Sevignani, C.5    Wentzel, E.6
  • 24
    • 48649099908 scopus 로고    scopus 로고
    • Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer
    • Nagel R., le Sage C., Diosdado B., van der Waal M., Vrielink J., Bolijn A., et al. Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. Cancer Res 2008, 68:5795-5802.
    • (2008) Cancer Res , vol.68 , pp. 5795-5802
    • Nagel, R.1    le Sage, C.2    Diosdado, B.3    van der Waal, M.4    Vrielink, J.5    Bolijn, A.6
  • 25
    • 73349125465 scopus 로고    scopus 로고
    • MicroRNAs in cancer: small molecules with a huge impact
    • Iorio M.V., Croce C.M. MicroRNAs in cancer: small molecules with a huge impact. J. Clin. Oncol 2009, 27:5848-5856.
    • (2009) J. Clin. Oncol , vol.27 , pp. 5848-5856
    • Iorio, M.V.1    Croce, C.M.2
  • 26
    • 38048999928 scopus 로고    scopus 로고
    • Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells
    • Biswas S., Trobridge P., Romero-Gallo J., Billheimer D., Myeroff L.L., Willson J.K., et al. Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells. Genes Chromosomes Cancer 2008, 47:95-106.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 95-106
    • Biswas, S.1    Trobridge, P.2    Romero-Gallo, J.3    Billheimer, D.4    Myeroff, L.L.5    Willson, J.K.6
  • 27
    • 79954987871 scopus 로고    scopus 로고
    • Colon cancer stem cells: implications in carcinogenesis
    • Sanders M.A., Majumdar A.P. Colon cancer stem cells: implications in carcinogenesis. Front. Biosci 2011, 16:1651-1662.
    • (2011) Front. Biosci , vol.16 , pp. 1651-1662
    • Sanders, M.A.1    Majumdar, A.P.2
  • 28
    • 50249173450 scopus 로고    scopus 로고
    • MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
    • Gabriely G., Wurdinger T., Kesari S., Esau C.C., Burchard J., Linsley P.S., et al. MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol. Cell. Biol 2008, 28:5369-5380.
    • (2008) Mol. Cell. Biol , vol.28 , pp. 5369-5380
    • Gabriely, G.1    Wurdinger, T.2    Kesari, S.3    Esau, C.C.4    Burchard, J.5    Linsley, P.S.6
  • 31
    • 78149234118 scopus 로고    scopus 로고
    • MiR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells
    • Cottonham C.L., Kaneko S., Xu L. miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells. J. Biol. Chem 2010, 285:35293-35302.
    • (2010) J. Biol. Chem , vol.285 , pp. 35293-35302
    • Cottonham, C.L.1    Kaneko, S.2    Xu, L.3
  • 32
    • 84878190315 scopus 로고    scopus 로고
    • MicroRNA expression profile in stage III colorectal cancer: circulating miR-18a and miR-29a as promising biomarkers
    • Brunet Vega A., Pericay C., Moya I., Ferrer A., Dotor E., Pisa A., et al. microRNA expression profile in stage III colorectal cancer: circulating miR-18a and miR-29a as promising biomarkers. Oncol. Rep 2013, 30:320-326.
    • (2013) Oncol. Rep , vol.30 , pp. 320-326
    • Brunet Vega, A.1    Pericay, C.2    Moya, I.3    Ferrer, A.4    Dotor, E.5    Pisa, A.6
  • 33
    • 84892903184 scopus 로고    scopus 로고
    • MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4
    • Tang W., Zhu Y., Gao J., Fu J., Liu C., Liu Y., et al. MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4. Br. J. Cancer 2014, 110:450-458.
    • (2014) Br. J. Cancer , vol.110 , pp. 450-458
    • Tang, W.1    Zhu, Y.2    Gao, J.3    Fu, J.4    Liu, C.5    Liu, Y.6
  • 34
    • 77953192081 scopus 로고    scopus 로고
    • Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer
    • Huang Z.H., Huang D., Ni S.J.A., Peng Z.L., Sheng W.Q., Du X. Plasma microRNAs are promising novel biomarkers for early detection of colorectal cancer. Int. J. Cancer 2010, 127:118-126.
    • (2010) Int. J. Cancer , vol.127 , pp. 118-126
    • Huang, Z.H.1    Huang, D.2    Ni, S.J.A.3    Peng, Z.L.4    Sheng, W.Q.5    Du, X.6
  • 35
    • 76349114730 scopus 로고    scopus 로고
    • Initial study of microRNA expression profiles of colonic cancer without lymph node metastasis
    • Wang Y.X., Zhang X.Y., Zhang B.F., Yang C.Q., Chen X.M., Gao H.J. Initial study of microRNA expression profiles of colonic cancer without lymph node metastasis. J. Dig. Dis 2010, 11:50-54.
    • (2010) J. Dig. Dis , vol.11 , pp. 50-54
    • Wang, Y.X.1    Zhang, X.Y.2    Zhang, B.F.3    Yang, C.Q.4    Chen, X.M.5    Gao, H.J.6
  • 36
    • 77951542711 scopus 로고    scopus 로고
    • Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappa B and microRNA network
    • Wang B.D., Kline C.L.B., Pastor D.M., Olson T.L., Frank B., Luu T., et al. Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappa B and microRNA network. Mol. Cancer 2010, 9.
    • (2010) Mol. Cancer , vol.9
    • Wang, B.D.1    Kline, C.L.B.2    Pastor, D.M.3    Olson, T.L.4    Frank, B.5    Luu, T.6
  • 37
    • 79751473114 scopus 로고    scopus 로고
    • The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
    • Liu C., Kelnar K., Liu B., Chen X., Calhoun-Davis T., Li H., et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat. Med 2011, 17:211-215.
    • (2011) Nat. Med , vol.17 , pp. 211-215
    • Liu, C.1    Kelnar, K.2    Liu, B.3    Chen, X.4    Calhoun-Davis, T.5    Li, H.6
  • 38
    • 75149124701 scopus 로고    scopus 로고
    • MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1
    • Sachdeva M., Mo Y.Y. MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1. Cancer Res 2010, 70:378-387.
    • (2010) Cancer Res , vol.70 , pp. 378-387
    • Sachdeva, M.1    Mo, Y.Y.2
  • 39
    • 57749099102 scopus 로고    scopus 로고
    • P53-Responsive microRNAs 192 and 215 are capable of inducing cell cycle arrest
    • Braun C.J., Zhang X., Savelyeva I., Wolff S., Moll U.M., Schepeler T., et al. p53-Responsive microRNAs 192 and 215 are capable of inducing cell cycle arrest. Cancer Res 2008, 68:10094-10104.
    • (2008) Cancer Res , vol.68 , pp. 10094-10104
    • Braun, C.J.1    Zhang, X.2    Savelyeva, I.3    Wolff, S.4    Moll, U.M.5    Schepeler, T.6
  • 40
    • 68149160861 scopus 로고    scopus 로고
    • MicroRNA expression profile in non-cancerous colonic tissue associated with lymph node metastasis of colon cancer
    • Huang Z.M., Yang J., Shen X.Y., Zhang X.Y., Meng F.S., Xu J.T., et al. MicroRNA expression profile in non-cancerous colonic tissue associated with lymph node metastasis of colon cancer. J. Dig. Dis 2009, 10:188-194.
    • (2009) J. Dig. Dis , vol.10 , pp. 188-194
    • Huang, Z.M.1    Yang, J.2    Shen, X.Y.3    Zhang, X.Y.4    Meng, F.S.5    Xu, J.T.6
  • 41
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U., Schubert J., Wellner U., Schmalhofer O., Vincan E., Spaderna S., et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008, 9:582-589.
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6
  • 43
    • 84870364798 scopus 로고    scopus 로고
    • Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family
    • Takahashi M., Sung B., Shen Y., Hur K., Link A., Boland C.R., et al. Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family. Carcinogenesis 2012, 33:2441-2449.
    • (2012) Carcinogenesis , vol.33 , pp. 2441-2449
    • Takahashi, M.1    Sung, B.2    Shen, Y.3    Hur, K.4    Link, A.5    Boland, C.R.6
  • 44
    • 65349162096 scopus 로고    scopus 로고
    • Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression
    • Peter M.E. Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression. Cell Cycle 2009, 8:843-852.
    • (2009) Cell Cycle , vol.8 , pp. 843-852
    • Peter, M.E.1
  • 45
    • 79952708320 scopus 로고    scopus 로고
    • MicroRNA dysregulation in colorectal cancer: a clinical perspective
    • Dong Y., Wu W.K., Wu C.W., Sung J.J., Yu J., Ng S.S. MicroRNA dysregulation in colorectal cancer: a clinical perspective. Br. J. Cancer 2011, 104:893-898.
    • (2011) Br. J. Cancer , vol.104 , pp. 893-898
    • Dong, Y.1    Wu, W.K.2    Wu, C.W.3    Sung, J.J.4    Yu, J.5    Ng, S.S.6
  • 46
    • 51649091930 scopus 로고    scopus 로고
    • Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis
    • Creighton C.J., Casa A., Lazard Z., Huang S.X., Tsimelzon A., Hilsenbeck S.G., et al. Insulin-like growth factor-I activates gene transcription programs strongly associated with poor breast cancer prognosis. J. Clin. Oncol 2008, 26:4078-4085.
    • (2008) J. Clin. Oncol , vol.26 , pp. 4078-4085
    • Creighton, C.J.1    Casa, A.2    Lazard, Z.3    Huang, S.X.4    Tsimelzon, A.5    Hilsenbeck, S.G.6
  • 47
    • 66649131351 scopus 로고    scopus 로고
    • The expression profile of microRNAs in a model of 7,12-dimethyl-benz[a]anthrance-induced oral carcinogenesis in Syrian hamster
    • Yu T., Wang X.Y., Gong R.G., Li A., Yang S., Cao Y.T., et al. The expression profile of microRNAs in a model of 7,12-dimethyl-benz[a]anthrance-induced oral carcinogenesis in Syrian hamster. J. Exp. Clin. Cancer Res 2009, 28:64.
    • (2009) J. Exp. Clin. Cancer Res , vol.28 , pp. 64
    • Yu, T.1    Wang, X.Y.2    Gong, R.G.3    Li, A.4    Yang, S.5    Cao, Y.T.6
  • 48
    • 77956921020 scopus 로고    scopus 로고
    • MicroRNA-21: from cancer to cardiovascular disease
    • Jazbutyte V., Thum T. MicroRNA-21: from cancer to cardiovascular disease. Curr. Drug Targets 2010, 11:926-935.
    • (2010) Curr. Drug Targets , vol.11 , pp. 926-935
    • Jazbutyte, V.1    Thum, T.2
  • 50
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    • Wellner U., Schubert J., Burk U.C., Schmalhofer O., Zhu F., Sonntag A., et al. The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat. Cell Biol 2009, 11:1487-1495.
    • (2009) Nat. Cell Biol , vol.11 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3    Schmalhofer, O.4    Zhu, F.5    Sonntag, A.6
  • 51
    • 77955516533 scopus 로고    scopus 로고
    • Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers
    • Yu L., Todd N.W., Xing L., Xie Y., Zhang H., Liu Z., et al. Early detection of lung adenocarcinoma in sputum by a panel of microRNA markers. Int. J. Cancer 2010, 127:2870-2878.
    • (2010) Int. J. Cancer , vol.127 , pp. 2870-2878
    • Yu, L.1    Todd, N.W.2    Xing, L.3    Xie, Y.4    Zhang, H.5    Liu, Z.6
  • 52
    • 84864307724 scopus 로고    scopus 로고
    • Negative regulation of miR-145 by C/EBP-beta through the Akt pathway in cancer cells
    • Sachdeva M., Liu Q., Cao J., Lu Z., Mo Y.Y. Negative regulation of miR-145 by C/EBP-beta through the Akt pathway in cancer cells. Nucleic Acids Res 2012, 40:6683-6692.
    • (2012) Nucleic Acids Res , vol.40 , pp. 6683-6692
    • Sachdeva, M.1    Liu, Q.2    Cao, J.3    Lu, Z.4    Mo, Y.Y.5
  • 53
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani I.A., Rasheed S.A., Nikolova D.A., Leupold J.H., Colburn N.H., Post S., et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008, 27:2128-2136.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6
  • 55
    • 58149093172 scopus 로고    scopus 로고
    • FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination
    • Dupont S., Mamidi A., Cordenonsi M., Montagner M., Zacchigna L., Adorno M., et al. FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination. Cell 2009, 136:123-135.
    • (2009) Cell , vol.136 , pp. 123-135
    • Dupont, S.1    Mamidi, A.2    Cordenonsi, M.3    Montagner, M.4    Zacchigna, L.5    Adorno, M.6
  • 56
    • 77950881915 scopus 로고    scopus 로고
    • Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer
    • Tsang W.P., Ng E.K., Ng S.S., Jin H., Yu J., Sung J.J., et al. Oncofetal H19-derived miR-675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis 2010, 31:350-358.
    • (2010) Carcinogenesis , vol.31 , pp. 350-358
    • Tsang, W.P.1    Ng, E.K.2    Ng, S.S.3    Jin, H.4    Yu, J.5    Sung, J.J.6
  • 57
    • 66049112674 scopus 로고    scopus 로고
    • Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening
    • Ng E.K., Chong W.W., Jin H., Lam E.K., Shin V.Y., Yu J., et al. Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening. Gut 2009, 58:1375-1381.
    • (2009) Gut , vol.58 , pp. 1375-1381
    • Ng, E.K.1    Chong, W.W.2    Jin, H.3    Lam, E.K.4    Shin, V.Y.5    Yu, J.6
  • 58
    • 80053442041 scopus 로고    scopus 로고
    • MiR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis
    • Beezhold K., Liu J., Kan H., Meighan T., Castranova V., Shi X., et al. miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis. Toxicol. Sci 2011, 123:411-420.
    • (2011) Toxicol. Sci , vol.123 , pp. 411-420
    • Beezhold, K.1    Liu, J.2    Kan, H.3    Meighan, T.4    Castranova, V.5    Shi, X.6
  • 59
    • 60549099721 scopus 로고    scopus 로고
    • Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis
    • Liu J., Weiss H.L., Rychahou P., Jackson L.N., Evers B.M., Gao T. Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis. Oncogene 2009, 28:994-1004.
    • (2009) Oncogene , vol.28 , pp. 994-1004
    • Liu, J.1    Weiss, H.L.2    Rychahou, P.3    Jackson, L.N.4    Evers, B.M.5    Gao, T.6
  • 60
    • 79953320835 scopus 로고    scopus 로고
    • MicroRNA-95 promotes cell proliferation and targets sorting Nexin 1 in human colorectal carcinoma
    • Huang Z., Huang S., Wang Q., Liang L., Ni S., Wang L., et al. MicroRNA-95 promotes cell proliferation and targets sorting Nexin 1 in human colorectal carcinoma. Cancer Res 2011, 71:2582-2589.
    • (2011) Cancer Res , vol.71 , pp. 2582-2589
    • Huang, Z.1    Huang, S.2    Wang, Q.3    Liang, L.4    Ni, S.5    Wang, L.6
  • 61
    • 79952432768 scopus 로고    scopus 로고
    • MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma
    • Sun K., Wang W., Zeng J.J., Wu C.T., Lei S.T., Li G.X. MicroRNA-221 inhibits CDKN1C/p57 expression in human colorectal carcinoma. Acta Pharmacol. Sin 2011, 32:375-384.
    • (2011) Acta Pharmacol. Sin , vol.32 , pp. 375-384
    • Sun, K.1    Wang, W.2    Zeng, J.J.3    Wu, C.T.4    Lei, S.T.5    Li, G.X.6
  • 62
    • 64149132942 scopus 로고    scopus 로고
    • MicroRNAs: novel biomarkers for human cancer
    • Bartels C.L., Tsongalis G.J. MicroRNAs: novel biomarkers for human cancer. Clin. Chem 2009, 55:623-631.
    • (2009) Clin. Chem , vol.55 , pp. 623-631
    • Bartels, C.L.1    Tsongalis, G.J.2
  • 63
    • 47549109566 scopus 로고    scopus 로고
    • MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
    • Lu Z., Liu M., Stribinskis V., Klinge C.M., Ramos K.S., Colburn N.H., et al. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 2008, 27:4373-4379.
    • (2008) Oncogene , vol.27 , pp. 4373-4379
    • Lu, Z.1    Liu, M.2    Stribinskis, V.3    Klinge, C.M.4    Ramos, K.S.5    Colburn, N.H.6
  • 64
    • 70349134366 scopus 로고    scopus 로고
    • MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets
    • Baffa R., Fassan M., Volinia S., O'Hara B., Liu C.G., Palazzo J.P., et al. MicroRNA expression profiling of human metastatic cancers identifies cancer gene targets. J. Pathol 2009, 219:214-221.
    • (2009) J. Pathol , vol.219 , pp. 214-221
    • Baffa, R.1    Fassan, M.2    Volinia, S.3    O'Hara, B.4    Liu, C.G.5    Palazzo, J.P.6
  • 65
    • 84863891322 scopus 로고    scopus 로고
    • MiR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4
    • Chen H.Y., Lin Y.M., Chung H.C., Lang Y.D., Lin C.J., Huang J., et al. miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4. Cancer Res 2012, 72:3631-3641.
    • (2012) Cancer Res , vol.72 , pp. 3631-3641
    • Chen, H.Y.1    Lin, Y.M.2    Chung, H.C.3    Lang, Y.D.4    Lin, C.J.5    Huang, J.6
  • 68
    • 36349012607 scopus 로고    scopus 로고
    • Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway
    • Ovcharenko D., Kelnar K., Johnson C., Leng N., Brown D. Genome-scale microRNA and small interfering RNA screens identify small RNA modulators of TRAIL-induced apoptosis pathway. Cancer Res 2007, 67:10782-10788.
    • (2007) Cancer Res , vol.67 , pp. 10782-10788
    • Ovcharenko, D.1    Kelnar, K.2    Johnson, C.3    Leng, N.4    Brown, D.5
  • 69
    • 83755205389 scopus 로고    scopus 로고
    • Prioritizing human cancer microRNAs based on genes' functional consistency between microRNA and cancer
    • Li X., Wang Q.H., Zheng Y., Lv S., Ning S.W., Sun J., et al. Prioritizing human cancer microRNAs based on genes' functional consistency between microRNA and cancer. Nucleic Acids Res 2011, 39.
    • (2011) Nucleic Acids Res , vol.39
    • Li, X.1    Wang, Q.H.2    Zheng, Y.3    Lv, S.4    Ning, S.W.5    Sun, J.6
  • 70
    • 70350433121 scopus 로고    scopus 로고
    • MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells
    • Borralho P.M., Kren B.T., Castro R.E., da Silva I.B., Steer C.J., Rodrigues C.M. MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells. FEBS J. 2009, 276:6689-6700.
    • (2009) FEBS J. , vol.276 , pp. 6689-6700
    • Borralho, P.M.1    Kren, B.T.2    Castro, R.E.3    da Silva, I.B.4    Steer, C.J.5    Rodrigues, C.M.6
  • 71
    • 84863168862 scopus 로고    scopus 로고
    • Up-regulated miR-17 promotes cell proliferation, tumour growth and cell cycle progression by targeting the RND3 tumour suppressor gene in colorectal carcinoma
    • Luo H., Zou J., Dong Z., Zeng Q., Wu D., Liu L. Up-regulated miR-17 promotes cell proliferation, tumour growth and cell cycle progression by targeting the RND3 tumour suppressor gene in colorectal carcinoma. Biochem. J. 2012, 442:311-321.
    • (2012) Biochem. J. , vol.442 , pp. 311-321
    • Luo, H.1    Zou, J.2    Dong, Z.3    Zeng, Q.4    Wu, D.5    Liu, L.6
  • 73
    • 57749179067 scopus 로고    scopus 로고
    • Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: a risk factor for colon cancer
    • Patel B.B., Yu Y., Du J., Levi E., Phillip P.A., Majumdar A.P. Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: a risk factor for colon cancer. Biochem. Biophys. Res. Commun 2009, 378:344-347.
    • (2009) Biochem. Biophys. Res. Commun , vol.378 , pp. 344-347
    • Patel, B.B.1    Yu, Y.2    Du, J.3    Levi, E.4    Phillip, P.A.5    Majumdar, A.P.6
  • 77
    • 70350233470 scopus 로고    scopus 로고
    • Metastamir: the field of metastasis-regulatory microRNA is spreading
    • Hurst D.R., Edmonds M.D., Welch D.R. Metastamir: the field of metastasis-regulatory microRNA is spreading. Cancer Res 2009, 69:7495-7498.
    • (2009) Cancer Res , vol.69 , pp. 7495-7498
    • Hurst, D.R.1    Edmonds, M.D.2    Welch, D.R.3
  • 80
    • 67449156113 scopus 로고    scopus 로고
    • Locked nucleic acid in situ hybridization analysis of miR-21 expression during colorectal cancer development
    • Yamamichi N., Shimomura R., Inada K.I., Sakurai K., Haraguchi T., Ozaki Y., et al. Locked nucleic acid in situ hybridization analysis of miR-21 expression during colorectal cancer development. Clin. Cancer Res 2009, 15:4009-4016.
    • (2009) Clin. Cancer Res , vol.15 , pp. 4009-4016
    • Yamamichi, N.1    Shimomura, R.2    Inada, K.I.3    Sakurai, K.4    Haraguchi, T.5    Ozaki, Y.6
  • 81
    • 77958198472 scopus 로고    scopus 로고
    • Rnd proteins: multifunctional regulators of the cytoskeleton and cell cycle progression
    • Riou P., Villalonga P., Ridley A.J. Rnd proteins: multifunctional regulators of the cytoskeleton and cell cycle progression. Bioessays 2010, 32:986-992.
    • (2010) Bioessays , vol.32 , pp. 986-992
    • Riou, P.1    Villalonga, P.2    Ridley, A.J.3
  • 82
    • 84858680315 scopus 로고    scopus 로고
    • Angiogenesis is controlled by miR-27b associated with endothelial tip cells
    • Melo S.A., Kalluri R. Angiogenesis is controlled by miR-27b associated with endothelial tip cells. Blood 2012, 119:2439-2440.
    • (2012) Blood , vol.119 , pp. 2439-2440
    • Melo, S.A.1    Kalluri, R.2
  • 83
    • 79957783544 scopus 로고    scopus 로고
    • Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23 similar to 27 similar to 24 clusters
    • Zhou Q.B., Gallagher R., Ufret-Vincenty R., Li X.Y., Olson E.N., Wang S.S. Regulation of angiogenesis and choroidal neovascularization by members of microRNA-23 similar to 27 similar to 24 clusters. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:8287-8292.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 8287-8292
    • Zhou, Q.B.1    Gallagher, R.2    Ufret-Vincenty, R.3    Li, X.Y.4    Olson, E.N.5    Wang, S.S.6
  • 84
    • 78649251518 scopus 로고    scopus 로고
    • MicroRNA expression profiling of exfoliated colonocytes isolated from feces for colorectal cancer screening
    • Koga Y., Yasunaga M., Takahashi A., Kuroda J., Moriya Y., Akasu T., et al. MicroRNA expression profiling of exfoliated colonocytes isolated from feces for colorectal cancer screening. Cancer Prev. Res 2010, 3:1435-1442.
    • (2010) Cancer Prev. Res , vol.3 , pp. 1435-1442
    • Koga, Y.1    Yasunaga, M.2    Takahashi, A.3    Kuroda, J.4    Moriya, Y.5    Akasu, T.6
  • 85
    • 77956305756 scopus 로고    scopus 로고
    • MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2
    • Dong Q., Meng P., Wang T., Qin W., Wang F., Yuan J., et al. MicroRNA let-7a inhibits proliferation of human prostate cancer cells in vitro and in vivo by targeting E2F2 and CCND2. PLoS ONE 2010, 5:e10147.
    • (2010) PLoS ONE , vol.5 , pp. e10147
    • Dong, Q.1    Meng, P.2    Wang, T.3    Qin, W.4    Wang, F.5    Yuan, J.6
  • 86
    • 77951620660 scopus 로고    scopus 로고
    • The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma
    • Shimizu S., Takehara T., Hikita H., Kodama T., Miyagi T., Hosui A., et al. The let-7 family of microRNAs inhibits Bcl-xL expression and potentiates sorafenib-induced apoptosis in human hepatocellular carcinoma. J. Hepatol 2010, 52:698-704.
    • (2010) J. Hepatol , vol.52 , pp. 698-704
    • Shimizu, S.1    Takehara, T.2    Hikita, H.3    Kodama, T.4    Miyagi, T.5    Hosui, A.6
  • 87
    • 84862877840 scopus 로고    scopus 로고
    • High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease
    • Ruzzo A., Graziano F., Vincenzi B., Canestrari E., Perrone G., Galluccio N., et al. High let-7a microRNA levels in KRAS-mutated colorectal carcinomas may rescue anti-EGFR therapy effects in patients with chemotherapy-refractory metastatic disease. Oncologist 2012, 17:823-829.
    • (2012) Oncologist , vol.17 , pp. 823-829
    • Ruzzo, A.1    Graziano, F.2    Vincenzi, B.3    Canestrari, E.4    Perrone, G.5    Galluccio, N.6
  • 88
    • 67649652208 scopus 로고    scopus 로고
    • BRAF mutation in metastatic colorectal cancer
    • Tol J., Nagtegaal I.D., Punt C.J. BRAF mutation in metastatic colorectal cancer. N. Engl. J. Med 2009, 361:98-99.
    • (2009) N. Engl. J. Med , vol.361 , pp. 98-99
    • Tol, J.1    Nagtegaal, I.D.2    Punt, C.J.3
  • 89
    • 77954368612 scopus 로고    scopus 로고
    • Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma
    • Earle J.S., Luthra R., Romans A., Abraham R., Ensor J., Yao H., et al. Association of microRNA expression with microsatellite instability status in colorectal adenocarcinoma. J. Mol. Diagn 2010, 12:433-440.
    • (2010) J. Mol. Diagn , vol.12 , pp. 433-440
    • Earle, J.S.1    Luthra, R.2    Romans, A.3    Abraham, R.4    Ensor, J.5    Yao, H.6
  • 90
    • 33646444884 scopus 로고    scopus 로고
    • Let-7 microRNA functions as a potential growth suppressor in human colon cancer cells
    • Akao Y., Nakagawa Y., Naoe T. let-7 microRNA functions as a potential growth suppressor in human colon cancer cells. Biol. Pharm. Bull 2006, 29:903-906.
    • (2006) Biol. Pharm. Bull , vol.29 , pp. 903-906
    • Akao, Y.1    Nakagawa, Y.2    Naoe, T.3
  • 91
    • 84870275439 scopus 로고    scopus 로고
    • Beyond KRAS mutation status: influence of KRAS copy number status and microRNAs on clinical outcome to cetuximab in metastatic colorectal cancer patients
    • Mekenkamp L.J., Tol J., Dijkstra J.R., de Krijger I., Vink-Borger M.E., van Vliet S., et al. Beyond KRAS mutation status: influence of KRAS copy number status and microRNAs on clinical outcome to cetuximab in metastatic colorectal cancer patients. BMC Cancer 2012, 12:292.
    • (2012) BMC Cancer , vol.12 , pp. 292
    • Mekenkamp, L.J.1    Tol, J.2    Dijkstra, J.R.3    de Krijger, I.4    Vink-Borger, M.E.5    van Vliet, S.6
  • 92
    • 84869195391 scopus 로고    scopus 로고
    • Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab
    • Kjersem J.B., Ikdahl T., Guren T., Skovlund E., Sorbye H., Hamfjord J., et al. Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab. BMC Cancer 2012, 12:534.
    • (2012) BMC Cancer , vol.12 , pp. 534
    • Kjersem, J.B.1    Ikdahl, T.2    Guren, T.3    Skovlund, E.4    Sorbye, H.5    Hamfjord, J.6
  • 93
    • 77957145245 scopus 로고    scopus 로고
    • Genetic modulation of the Let-7 microRNA binding to KRAS 3'-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan
    • Graziano F., Canestrari E., Loupakis F., Ruzzo A., Galluccio N., Santini D., et al. Genetic modulation of the Let-7 microRNA binding to KRAS 3'-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan. Pharmacogenomics J. 2010, 10:458-464.
    • (2010) Pharmacogenomics J. , vol.10 , pp. 458-464
    • Graziano, F.1    Canestrari, E.2    Loupakis, F.3    Ruzzo, A.4    Galluccio, N.5    Santini, D.6
  • 94
    • 78650321266 scopus 로고    scopus 로고
    • A let-7 microRNA-binding site polymorphism in 3'-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapy
    • Zhang W., Winder T., Ning Y., Pohl A., Yang D., Kahn M., et al. A let-7 microRNA-binding site polymorphism in 3'-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapy. Ann. Oncol 2011, 22:104-109.
    • (2011) Ann. Oncol , vol.22 , pp. 104-109
    • Zhang, W.1    Winder, T.2    Ning, Y.3    Pohl, A.4    Yang, D.5    Kahn, M.6
  • 95
    • 48449084118 scopus 로고    scopus 로고
    • Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells
    • Marson A., Levine S.S., Cole M.F., Frampton G.M., Brambrink T., Johnstone S., et al. Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell 2008, 134:521-533.
    • (2008) Cell , vol.134 , pp. 521-533
    • Marson, A.1    Levine, S.S.2    Cole, M.F.3    Frampton, G.M.4    Brambrink, T.5    Johnstone, S.6
  • 96
    • 80052195502 scopus 로고    scopus 로고
    • Genome-wide profiling of chromatin signatures reveals epigenetic regulation of microRNA genes in colorectal cancer
    • Suzuki H., Takatsuka S., Akashi H., Yamamoto E., Nojima M., Maruyama R., et al. Genome-wide profiling of chromatin signatures reveals epigenetic regulation of microRNA genes in colorectal cancer. Cancer Res 2011, 71:5646-5658.
    • (2011) Cancer Res , vol.71 , pp. 5646-5658
    • Suzuki, H.1    Takatsuka, S.2    Akashi, H.3    Yamamoto, E.4    Nojima, M.5    Maruyama, R.6
  • 97
    • 49249121155 scopus 로고    scopus 로고
    • Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer
    • Toyota M., Suzuki H., Sasaki Y., Maruyama R., Imai K., Shinomura Y., et al. Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer. Cancer Res 2008, 68:4123-4132.
    • (2008) Cancer Res , vol.68 , pp. 4123-4132
    • Toyota, M.1    Suzuki, H.2    Sasaki, Y.3    Maruyama, R.4    Imai, K.5    Shinomura, Y.6
  • 98
  • 100
    • 39049128249 scopus 로고    scopus 로고
    • Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer
    • Slaby O., Svoboda M., Fabian P., Smerdova T., Knoflickova D., Bednarikova M., et al. Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer. Oncology 2007, 72:397-402.
    • (2007) Oncology , vol.72 , pp. 397-402
    • Slaby, O.1    Svoboda, M.2    Fabian, P.3    Smerdova, T.4    Knoflickova, D.5    Bednarikova, M.6
  • 101
    • 78149320174 scopus 로고    scopus 로고
    • MicroRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2
    • Zhang H., Cai X., Wang Y., Tang H., Tong D., Ji F. MicroRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2. Oncol. Rep 2010, 24:1363-1369.
    • (2010) Oncol. Rep , vol.24 , pp. 1363-1369
    • Zhang, H.1    Cai, X.2    Wang, Y.3    Tang, H.4    Tong, D.5    Ji, F.6
  • 102
    • 62249137047 scopus 로고    scopus 로고
    • Role of miR-143 targeting KRAS in colorectal tumorigenesis
    • Chen X., Guo X., Zhang H., Xiang Y., Chen J., Yin Y., et al. Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene 2009, 28:1385-1392.
    • (2009) Oncogene , vol.28 , pp. 1385-1392
    • Chen, X.1    Guo, X.2    Zhang, H.3    Xiang, Y.4    Chen, J.5    Yin, Y.6
  • 103
    • 68749097208 scopus 로고    scopus 로고
    • MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer
    • Ng E.K., Tsang W.P., Ng S.S., Jin H.C., Yu J., Li J.J., et al. MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. Br. J. Cancer 2009, 101:699-706.
    • (2009) Br. J. Cancer , vol.101 , pp. 699-706
    • Ng, E.K.1    Tsang, W.P.2    Ng, S.S.3    Jin, H.C.4    Yu, J.5    Li, J.J.6
  • 105
    • 84862908024 scopus 로고    scopus 로고
    • MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis
    • Xu Q., Liu L.Z., Qian X., Chen Q., Jiang Y., Li D., et al. miR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis. Nucleic Acids Res 2012, 40:761-774.
    • (2012) Nucleic Acids Res , vol.40 , pp. 761-774
    • Xu, Q.1    Liu, L.Z.2    Qian, X.3    Chen, Q.4    Jiang, Y.5    Li, D.6
  • 106
  • 108
    • 78650693188 scopus 로고    scopus 로고
    • Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene friend leukemia virus integration 1 gene
    • Zhang J.J., Guo H.Y., Zhang H., Wang H.B., Qian G.X., Fan X.Q., et al. Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene friend leukemia virus integration 1 gene. Cancer 2011, 117:86-95.
    • (2011) Cancer , vol.117 , pp. 86-95
    • Zhang, J.J.1    Guo, H.Y.2    Zhang, H.3    Wang, H.B.4    Qian, G.X.5    Fan, X.Q.6
  • 109
    • 67649373019 scopus 로고    scopus 로고
    • Mechanism of growth inhibition by microRNA 145: the role of the IGF-I receptor signaling pathway
    • La Rocca G., Badin M., Shi B., Xu S.Q., Deangelis T., Sepp-Lorenzinoi L., et al. Mechanism of growth inhibition by microRNA 145: the role of the IGF-I receptor signaling pathway. J. Cell. Physiol 2009, 220:485-491.
    • (2009) J. Cell. Physiol , vol.220 , pp. 485-491
    • La Rocca, G.1    Badin, M.2    Shi, B.3    Xu, S.Q.4    Deangelis, T.5    Sepp-Lorenzinoi, L.6
  • 110
    • 36348994146 scopus 로고    scopus 로고
    • Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells
    • Shi B., Sepp-Lorenzino L., Prisco M., Linsley P., DeAngelis T., Baserga R. Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells. J. Biol. Chem 2007, 282:32582-32590.
    • (2007) J. Biol. Chem , vol.282 , pp. 32582-32590
    • Shi, B.1    Sepp-Lorenzino, L.2    Prisco, M.3    Linsley, P.4    DeAngelis, T.5    Baserga, R.6
  • 112
    • 70450260597 scopus 로고    scopus 로고
    • Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer
    • Arndt G.M., Dossey L., Cullen L.M., Lai A., Druker R., Eisbacher M., et al. Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer. BMC Cancer 2009, 9.
    • (2009) BMC Cancer , vol.9
    • Arndt, G.M.1    Dossey, L.2    Cullen, L.M.3    Lai, A.4    Druker, R.5    Eisbacher, M.6
  • 113
    • 79952308806 scopus 로고    scopus 로고
    • Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b
    • Ma Y.L., Zhang P., Wang F., Moyer M.P., Yang J.J., Liu Z.H., et al. Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b. J. Cell. Mol. Med 2011, 15:1941-1954.
    • (2011) J. Cell. Mol. Med , vol.15 , pp. 1941-1954
    • Ma, Y.L.1    Zhang, P.2    Wang, F.3    Moyer, M.P.4    Yang, J.J.5    Liu, Z.H.6
  • 114
    • 79956298812 scopus 로고    scopus 로고
    • Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status
    • Van Cutsem E., Kohne C.H., Lang I., Folprecht G., Nowacki M.P., Cascinu S., et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J. Clin. Oncol 2011, 29:2011-2019.
    • (2011) J. Clin. Oncol , vol.29 , pp. 2011-2019
    • Van Cutsem, E.1    Kohne, C.H.2    Lang, I.3    Folprecht, G.4    Nowacki, M.P.5    Cascinu, S.6
  • 115
    • 44449125989 scopus 로고    scopus 로고
    • Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer
    • Grady W.M., Parkin R.K., Mitchell P.S., Lee J.H., Kim Y.H., Tsuchiya K.D., et al. Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer. Oncogene 2008, 27:3880-3888.
    • (2008) Oncogene , vol.27 , pp. 3880-3888
    • Grady, W.M.1    Parkin, R.K.2    Mitchell, P.S.3    Lee, J.H.4    Kim, Y.H.5    Tsuchiya, K.D.6
  • 116
    • 52249096359 scopus 로고    scopus 로고
    • The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers
    • Guo C.G., Sah J.F., Beard L., Willson J.K.V., Markowitz S.D., Guda K. The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. Genes Chromosomes Cancer 2008, 47:939-946.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 939-946
    • Guo, C.G.1    Sah, J.F.2    Beard, L.3    Willson, J.K.V.4    Markowitz, S.D.5    Guda, K.6
  • 117
    • 80052296784 scopus 로고    scopus 로고
    • Mybl2, downregulated during colon epithelial cell maturation, is suppressed by miR-365
    • Papetti M., Augenlicht L.H. Mybl2, downregulated during colon epithelial cell maturation, is suppressed by miR-365. Am. J. Physiol. Gastrointest. Liver Physiol 2011, 301:G508-G518.
    • (2011) Am. J. Physiol. Gastrointest. Liver Physiol , vol.301 , pp. G508-G518
    • Papetti, M.1    Augenlicht, L.H.2
  • 118
    • 79961189334 scopus 로고    scopus 로고
    • MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer
    • Tang J.T., Wang J.L., Du W., Hong J., Zhao S.L., Wang Y.C., et al. MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer. Carcinogenesis 2011, 32:1207-1215.
    • (2011) Carcinogenesis , vol.32 , pp. 1207-1215
    • Tang, J.T.1    Wang, J.L.2    Du, W.3    Hong, J.4    Zhao, S.L.5    Wang, Y.C.6
  • 120
    • 0344708478 scopus 로고    scopus 로고
    • Anticancer antifolates: current status and future directions
    • McGuire J.J. Anticancer antifolates: current status and future directions. Curr. Pharm. Des 2003, 9:2593-2613.
    • (2003) Curr. Pharm. Des , vol.9 , pp. 2593-2613
    • McGuire, J.J.1
  • 121
    • 77949495697 scopus 로고    scopus 로고
    • MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism
    • Mishra P.J., Song B., Wang Y., Humeniuk R., Banerjee D., Merlino G., et al. miR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism. PLoS ONE 2009, 4.
    • (2009) PLoS ONE , vol.4
    • Mishra, P.J.1    Song, B.2    Wang, Y.3    Humeniuk, R.4    Banerjee, D.5    Merlino, G.6
  • 122
    • 71049136170 scopus 로고    scopus 로고
    • MicroRNAs in colorectal cancer: translation of molecular biology into clinical application
    • Slaby O., Svoboda M., Michalek J., Vyzula R. MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol. Cancer 2009, 8:102.
    • (2009) Mol. Cancer , vol.8 , pp. 102
    • Slaby, O.1    Svoboda, M.2    Michalek, J.3    Vyzula, R.4
  • 123
    • 34249817549 scopus 로고    scopus 로고
    • Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis
    • Chang T.C., Wentzel E.A., Kent O.A., Ramachandran K., Mullendore M., Lee K.H., et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. Mol. Cell 2007, 26:745-752.
    • (2007) Mol. Cell , vol.26 , pp. 745-752
    • Chang, T.C.1    Wentzel, E.A.2    Kent, O.A.3    Ramachandran, K.4    Mullendore, M.5    Lee, K.H.6
  • 124
    • 77955478900 scopus 로고    scopus 로고
    • MiR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation
    • Boni V., Bitarte N., Cristobal I., Zarate R., Rodriguez J., Maiello E., et al. miR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation. Mol. Cancer Ther 2010, 9:2265-2275.
    • (2010) Mol. Cancer Ther , vol.9 , pp. 2265-2275
    • Boni, V.1    Bitarte, N.2    Cristobal, I.3    Zarate, R.4    Rodriguez, J.5    Maiello, E.6
  • 125
    • 57749116172 scopus 로고    scopus 로고
    • Coordinated regulation of cell cycle transcripts by p53-inducible microRNAs, miR-192 and miR-215
    • Georges S.A., Biery M.C., Kim S.Y., Schelter J.M., Guo J., Chang A.N., et al. Coordinated regulation of cell cycle transcripts by p53-inducible microRNAs, miR-192 and miR-215. Cancer Res 2008, 68:10105-10112.
    • (2008) Cancer Res , vol.68 , pp. 10105-10112
    • Georges, S.A.1    Biery, M.C.2    Kim, S.Y.3    Schelter, J.M.4    Guo, J.5    Chang, A.N.6
  • 126
    • 79960036643 scopus 로고    scopus 로고
    • MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1
    • Wang H., Wu J., Meng X., Ying X., Zuo Y., Liu R., et al. MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1. Carcinogenesis 2011, 32:1033-1042.
    • (2011) Carcinogenesis , vol.32 , pp. 1033-1042
    • Wang, H.1    Wu, J.2    Meng, X.3    Ying, X.4    Zuo, Y.5    Liu, R.6
  • 127
    • 77956790226 scopus 로고    scopus 로고
    • MicroRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells
    • Liu L., Chen L., Xu Y.X., Li R., Du X.H. MicroRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells. Biochem. Biophys. Res. Commun 2010, 400:236-240.
    • (2010) Biochem. Biophys. Res. Commun , vol.400 , pp. 236-240
    • Liu, L.1    Chen, L.2    Xu, Y.X.3    Li, R.4    Du, X.H.5
  • 128
    • 77955492383 scopus 로고    scopus 로고
    • Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells
    • Nakano H., Miyazawa T., Kinoshita K., Yamada Y., Yoshida T. Functional screening identifies a microRNA, miR-491 that induces apoptosis by targeting Bcl-X(L) in colorectal cancer cells. Int. J. Cancer 2010, 127:1072-1080.
    • (2010) Int. J. Cancer , vol.127 , pp. 1072-1080
    • Nakano, H.1    Miyazawa, T.2    Kinoshita, K.3    Yamada, Y.4    Yoshida, T.5
  • 130
    • 77955456047 scopus 로고    scopus 로고
    • MiR-133b regulates the MET proto-oncogene and inhibits the growth of colorectal cancer cells in vitro and in vivo
    • Hu G., Chen D.J., Li X.R., Yang K.Y., Wang H.X., Wu W. miR-133b regulates the MET proto-oncogene and inhibits the growth of colorectal cancer cells in vitro and in vivo. Cancer Biol. Ther 2010, 10:190-197.
    • (2010) Cancer Biol. Ther , vol.10 , pp. 190-197
    • Hu, G.1    Chen, D.J.2    Li, X.R.3    Yang, K.Y.4    Wang, H.X.5    Wu, W.6
  • 131
    • 84857978490 scopus 로고    scopus 로고
    • MicroRNA-214 inhibits angiogenesis by targeting quaking and reducing angiogenic growth factor release
    • van Mil A., Grundmann S., Goumans M.J., Lei Z.Y., Oerlemans M.I., Jaksani S., et al. MicroRNA-214 inhibits angiogenesis by targeting quaking and reducing angiogenic growth factor release. Cardiovas Res 2012, 93:655-665.
    • (2012) Cardiovas Res , vol.93 , pp. 655-665
    • van Mil, A.1    Grundmann, S.2    Goumans, M.J.3    Lei, Z.Y.4    Oerlemans, M.I.5    Jaksani, S.6
  • 132
    • 80054919770 scopus 로고    scopus 로고
    • MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1
    • Chamorro-Jorganes A., Araldi E., Penalva L.O.F., Sandhu D., Fernandez-Hernando C., Suarez Y. MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1. Arterioscler. Thromb. Vasc. Biol 2011, 31:2595-2606.
    • (2011) Arterioscler. Thromb. Vasc. Biol , vol.31 , pp. 2595-2606
    • Chamorro-Jorganes, A.1    Araldi, E.2    Penalva, L.O.F.3    Sandhu, D.4    Fernandez-Hernando, C.5    Suarez, Y.6
  • 133
    • 77949424429 scopus 로고    scopus 로고
    • Progress and prospects: immune responses to viral vectors
    • Nayak S., Herzog R.W. Progress and prospects: immune responses to viral vectors. Gene Ther 2010, 17:295-304.
    • (2010) Gene Ther , vol.17 , pp. 295-304
    • Nayak, S.1    Herzog, R.W.2
  • 134
    • 77950665077 scopus 로고    scopus 로고
    • Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
    • Ma L., Reinhardt F., Pan E., Soutschek J., Bhat B., Marcusson E.G., et al. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nat. Biotechnol 2010, 28:341-347.
    • (2010) Nat. Biotechnol , vol.28 , pp. 341-347
    • Ma, L.1    Reinhardt, F.2    Pan, E.3    Soutschek, J.4    Bhat, B.5    Marcusson, E.G.6
  • 135
  • 136
    • 80052841078 scopus 로고    scopus 로고
    • MicroRNA regulation of cancer stem cells
    • Liu C., Tang D.G. MicroRNA regulation of cancer stem cells. Cancer Res 2011, 71:5950-5954.
    • (2011) Cancer Res , vol.71 , pp. 5950-5954
    • Liu, C.1    Tang, D.G.2
  • 137
    • 79953043006 scopus 로고    scopus 로고
    • Transforming growth factor-beta regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM
    • Wang Y., Yu Y., Tsuyada A., Ren X., Wu X., Stubblefield K., et al. Transforming growth factor-beta regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM. Oncogene 2011, 30:1470-1480.
    • (2011) Oncogene , vol.30 , pp. 1470-1480
    • Wang, Y.1    Yu, Y.2    Tsuyada, A.3    Ren, X.4    Wu, X.5    Stubblefield, K.6
  • 141
    • 84874159230 scopus 로고    scopus 로고
    • Effect of miR-221-specific inhibitor on the proliferation and apoptosis of human colorectal carcinoma cells
    • Wang W., Sun K., Wu C.T., Lei S.T., Zeng J.J., Wu Y.J., et al. Effect of miR-221-specific inhibitor on the proliferation and apoptosis of human colorectal carcinoma cells. Nan Fang Yi Ke Da Xue Xue Bao 2011, 31:674-677.
    • (2011) Nan Fang Yi Ke Da Xue Xue Bao , vol.31 , pp. 674-677
    • Wang, W.1    Sun, K.2    Wu, C.T.3    Lei, S.T.4    Zeng, J.J.5    Wu, Y.J.6
  • 142
    • 80053528523 scopus 로고    scopus 로고
    • Colorectal cancers with microsatellite instability display unique miRNA profiles
    • Balaguer F., Moreira L., Lozano J.J., Link A., Ramirez G., Shen Y., et al. Colorectal cancers with microsatellite instability display unique miRNA profiles. Clin. Cancer Res 2011, 17:6239-6249.
    • (2011) Clin. Cancer Res , vol.17 , pp. 6239-6249
    • Balaguer, F.1    Moreira, L.2    Lozano, J.J.3    Link, A.4    Ramirez, G.5    Shen, Y.6
  • 143
  • 144
    • 79960963683 scopus 로고    scopus 로고
    • MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma
    • Ibrahim A.F., Weirauch U., Thomas M., Grunweller A., Hartmann R.K., Aigner A. MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma. Cancer Res 2011, 71:5214-5224.
    • (2011) Cancer Res , vol.71 , pp. 5214-5224
    • Ibrahim, A.F.1    Weirauch, U.2    Thomas, M.3    Grunweller, A.4    Hartmann, R.K.5    Aigner, A.6
  • 145
    • 84859603174 scopus 로고    scopus 로고
    • Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps
    • Wu C.W., Ng S.S.M., Dong Y.J., Ng S.C., Leung W.W., Lee C.W., et al. Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps. Gut 2012, 61:739-745.
    • (2012) Gut , vol.61 , pp. 739-745
    • Wu, C.W.1    Ng, S.S.M.2    Dong, Y.J.3    Ng, S.C.4    Leung, W.W.5    Lee, C.W.6
  • 146
    • 79951469197 scopus 로고    scopus 로고
    • AP-1-dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells
    • Misawa A., Katayama R., Koike S., Tomida A., Watanabe T., Fujita N. AP-1-dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells. Oncol. Res 2010, 19:23-33.
    • (2010) Oncol. Res , vol.19 , pp. 23-33
    • Misawa, A.1    Katayama, R.2    Koike, S.3    Tomida, A.4    Watanabe, T.5    Fujita, N.6
  • 147
    • 33645135862 scopus 로고    scopus 로고
    • Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?
    • Weiler J., Hunziker J., Hall J. Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease?. Gene Ther 2006, 13:496-502.
    • (2006) Gene Ther , vol.13 , pp. 496-502
    • Weiler, J.1    Hunziker, J.2    Hall, J.3
  • 148
    • 84859464569 scopus 로고    scopus 로고
    • Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies
    • Pritchard C.C., Kroh E., Wood B., Arroyo J.D., Dougherty K.J., Miyaji M.M., et al. Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies. Cancer Prev. Res 2012, 5:492-497.
    • (2012) Cancer Prev. Res , vol.5 , pp. 492-497
    • Pritchard, C.C.1    Kroh, E.2    Wood, B.3    Arroyo, J.D.4    Dougherty, K.J.5    Miyaji, M.M.6
  • 149
    • 79952717245 scopus 로고    scopus 로고
    • Genomic and epigenomic integration identifies a prognostic signature in colon cancer
    • Yi J.M., Dhir M., Van Neste L., Downing S.R., Jeschke J., Glockner S.C., et al. Genomic and epigenomic integration identifies a prognostic signature in colon cancer. Clin. Cancer Res 2011, 17:1535-1545.
    • (2011) Clin. Cancer Res , vol.17 , pp. 1535-1545
    • Yi, J.M.1    Dhir, M.2    Van Neste, L.3    Downing, S.R.4    Jeschke, J.5    Glockner, S.C.6
  • 150
    • 78650505164 scopus 로고    scopus 로고
    • Specific alterations of microRNA transcriptome and global network structure in colorectal carcinoma after cetuximab treatment
    • Ragusa M., Majorana A., Statello L., Maugeri M., Salito L., Barbagallo D., et al. Specific alterations of microRNA transcriptome and global network structure in colorectal carcinoma after cetuximab treatment. Mol. Cancer Ther 2010, 9:3396-3409.
    • (2010) Mol. Cancer Ther , vol.9 , pp. 3396-3409
    • Ragusa, M.1    Majorana, A.2    Statello, L.3    Maugeri, M.4    Salito, L.5    Barbagallo, D.6
  • 151
    • 49149128798 scopus 로고    scopus 로고
    • Overlapping expression of microRNAs in human embryonic colon and colorectal cancer
    • Monzo M., Navarro A., Bandres E., Artells R., Moreno I., Gel B., et al. Overlapping expression of microRNAs in human embryonic colon and colorectal cancer. Cell Res 2008, 18:823-833.
    • (2008) Cell Res , vol.18 , pp. 823-833
    • Monzo, M.1    Navarro, A.2    Bandres, E.3    Artells, R.4    Moreno, I.5    Gel, B.6
  • 153
    • 79957458567 scopus 로고    scopus 로고
    • Cell-free nucleic acids as biomarkers in cancer patients
    • Schwarzenbach H., Hoon D.S., Pantel K. Cell-free nucleic acids as biomarkers in cancer patients. Nat. Rev. Cancer 2011, 11:426-437.
    • (2011) Nat. Rev. Cancer , vol.11 , pp. 426-437
    • Schwarzenbach, H.1    Hoon, D.S.2    Pantel, K.3
  • 155
    • 69949110770 scopus 로고    scopus 로고
    • Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection
    • Park N.J., Zhou H., Elashoff D., Henson B.S., Kastratovic D.A., Abemayor E., et al. Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection. Clin. Cancer Res 2009, 15:5473-5477.
    • (2009) Clin. Cancer Res , vol.15 , pp. 5473-5477
    • Park, N.J.1    Zhou, H.2    Elashoff, D.3    Henson, B.S.4    Kastratovic, D.A.5    Abemayor, E.6
  • 156
    • 72449187466 scopus 로고    scopus 로고
    • Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer
    • Xie Y., Todd N.W., Liu Z., Zhan M., Fang H., Peng H., et al. Altered miRNA expression in sputum for diagnosis of non-small cell lung cancer. Lung Cancer 2010, 67:170-176.
    • (2010) Lung Cancer , vol.67 , pp. 170-176
    • Xie, Y.1    Todd, N.W.2    Liu, Z.3    Zhan, M.4    Fang, H.5    Peng, H.6
  • 160
    • 77950594400 scopus 로고    scopus 로고
    • Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth
    • Barkan D., Green J.E., Chambers A.F. Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth. Eur. J. Cancer 2010, 46:1181-1188.
    • (2010) Eur. J. Cancer , vol.46 , pp. 1181-1188
    • Barkan, D.1    Green, J.E.2    Chambers, A.F.3
  • 161
    • 79952711083 scopus 로고    scopus 로고
    • Moving closer to a prognostic DNA methylation signature in colon cancer
    • Carmona F.J., Esteller M. Moving closer to a prognostic DNA methylation signature in colon cancer. Clin. Cancer Res 2011, 17:1215-1217.
    • (2011) Clin. Cancer Res , vol.17 , pp. 1215-1217
    • Carmona, F.J.1    Esteller, M.2
  • 164
    • 77955591555 scopus 로고    scopus 로고
    • MicroRNAs and their target gene networks in breast cancer
    • Day E.O., Lal A. MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res 2010, 12:201.
    • (2010) Breast Cancer Res , vol.12 , pp. 201
    • Day, E.O.1    Lal, A.2
  • 165
    • 77956704233 scopus 로고    scopus 로고
    • Rapid in situ codetection of noncoding RNAs and proteins in cells and formalin-fixed paraffin-embedded tissue sections without protease treatment
    • de Planell-Saguer M., Rodicio M.C., Mourelatos Z. Rapid in situ codetection of noncoding RNAs and proteins in cells and formalin-fixed paraffin-embedded tissue sections without protease treatment. Nat. Protoc 2010, 5:1061-1073.
    • (2010) Nat. Protoc , vol.5 , pp. 1061-1073
    • de Planell-Saguer, M.1    Rodicio, M.C.2    Mourelatos, Z.3
  • 167
    • 78149408296 scopus 로고    scopus 로고
    • A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer
    • Hanke M., Hoefig K., Merz H., Feller A.C., Kausch I., Jocham D., et al. A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer. Urol. Oncol 2010, 28:655-661.
    • (2010) Urol. Oncol , vol.28 , pp. 655-661
    • Hanke, M.1    Hoefig, K.2    Merz, H.3    Feller, A.C.4    Kausch, I.5    Jocham, D.6
  • 168
    • 45449093192 scopus 로고    scopus 로고
    • MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer
    • Taylor D.D., Gercel-Taylor C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol. Oncol 2008, 110:13-21.
    • (2008) Gynecol. Oncol , vol.110 , pp. 13-21
    • Taylor, D.D.1    Gercel-Taylor, C.2
  • 169
    • 62449284551 scopus 로고    scopus 로고
    • Bcl2 family proteins in carcinogenesis and the treatment of cancer
    • Frenzel A., Grespi F., Chmelewskij W., Villunger A. Bcl2 family proteins in carcinogenesis and the treatment of cancer. Apoptosis 2009, 14:584-596.
    • (2009) Apoptosis , vol.14 , pp. 584-596
    • Frenzel, A.1    Grespi, F.2    Chmelewskij, W.3    Villunger, A.4
  • 170
    • 63149129655 scopus 로고    scopus 로고
    • Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy
    • Kang M.H., Reynolds C.P. Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy. Clin. Cancer Res 2009, 15:1126-1132.
    • (2009) Clin. Cancer Res , vol.15 , pp. 1126-1132
    • Kang, M.H.1    Reynolds, C.P.2
  • 171
    • 46149092748 scopus 로고    scopus 로고
    • Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment
    • Jiang B.H., Liu L.Z. Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment. Drug Resist. Updat 2008, 11:63-76.
    • (2008) Drug Resist. Updat , vol.11 , pp. 63-76
    • Jiang, B.H.1    Liu, L.Z.2
  • 172
    • 34047264639 scopus 로고    scopus 로고
    • Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors
    • Woods K., Thomson J.M., Hammond S.M. Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors. J. Biol. Chem 2007, 282:2130-2134.
    • (2007) J. Biol. Chem , vol.282 , pp. 2130-2134
    • Woods, K.1    Thomson, J.M.2    Hammond, S.M.3
  • 173
    • 68749119636 scopus 로고    scopus 로고
    • MiR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression
    • Diosdado B., van de Wiel M.A., Terhaar Sive Droste J.S., Mongera S., Postma C., Meijerink W.J., et al. miR-17-92 cluster is associated with 13q gain and c-myc expression during colorectal adenoma to adenocarcinoma progression. Br. J. Cancer 2009, 101:707-714.
    • (2009) Br. J. Cancer , vol.101 , pp. 707-714
    • Diosdado, B.1    van de Wiel, M.A.2    Terhaar Sive Droste, J.S.3    Mongera, S.4    Postma, C.5    Meijerink, W.J.6
  • 175
    • 77950441705 scopus 로고    scopus 로고
    • Feud or friend? The role of the miR-17-92 cluster in tumorigenesis
    • Xiang J., Wu J. Feud or friend? The role of the miR-17-92 cluster in tumorigenesis. Curr. Genomics 2010, 11:129-135.
    • (2010) Curr. Genomics , vol.11 , pp. 129-135
    • Xiang, J.1    Wu, J.2
  • 176
    • 34447270490 scopus 로고    scopus 로고
    • Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors
    • Leupold J.H., Yang H.S., Colburn N.H., Asangani I., Post S., Allgayer H. Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors. Oncogene 2007, 26:4550-4562.
    • (2007) Oncogene , vol.26 , pp. 4550-4562
    • Leupold, J.H.1    Yang, H.S.2    Colburn, N.H.3    Asangani, I.4    Post, S.5    Allgayer, H.6
  • 177
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar M.S., Lu J., Mercer K.L., Golub T.R., Jacks T. Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat. Genet 2007, 39:673-677.
    • (2007) Nat. Genet , vol.39 , pp. 673-677
    • Kumar, M.S.1    Lu, J.2    Mercer, K.L.3    Golub, T.R.4    Jacks, T.5
  • 178
    • 84875316099 scopus 로고    scopus 로고
    • CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a
    • Muppala S., Mudduluru G., Leupold J.H., Buergy D., Sleeman J.P., Allgayer H. CD24 induces expression of the oncomir miR-21 via Src, and CD24 and Src are both post-transcriptionally downregulated by the tumor suppressor miR-34a. PLoS ONE 2013, 8:e59563.
    • (2013) PLoS ONE , vol.8 , pp. e59563
    • Muppala, S.1    Mudduluru, G.2    Leupold, J.H.3    Buergy, D.4    Sleeman, J.P.5    Allgayer, H.6
  • 179
    • 84855389885 scopus 로고    scopus 로고
    • MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFbetaR2) in colon cancer cells
    • Yu Y., Kanwar S.S., Patel B.B., Oh P.S., Nautiyal J., Sarkar F.H., et al. MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFbetaR2) in colon cancer cells. Carcinogenesis 2012, 33:68-76.
    • (2012) Carcinogenesis , vol.33 , pp. 68-76
    • Yu, Y.1    Kanwar, S.S.2    Patel, B.B.3    Oh, P.S.4    Nautiyal, J.5    Sarkar, F.H.6
  • 180
    • 60549100868 scopus 로고    scopus 로고
    • Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-beta signaling
    • Li X., Wang Y., Sharif-Afshar A.R., Uwamariya C., Yi A., Ishii K., et al. Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-beta signaling. Differentiation 2009, 77:95-102.
    • (2009) Differentiation , vol.77 , pp. 95-102
    • Li, X.1    Wang, Y.2    Sharif-Afshar, A.R.3    Uwamariya, C.4    Yi, A.5    Ishii, K.6
  • 181
    • 84875780020 scopus 로고    scopus 로고
    • Down-regulation of miR-21 induces differentiation of chemoresistant colon cancer cells and enhances susceptibility to therapeutic regimens
    • Yu Y., Sarkar F.H., Majumdar A.P. Down-regulation of miR-21 induces differentiation of chemoresistant colon cancer cells and enhances susceptibility to therapeutic regimens. Transl. Oncol 2013, 6:180-186.
    • (2013) Transl. Oncol , vol.6 , pp. 180-186
    • Yu, Y.1    Sarkar, F.H.2    Majumdar, A.P.3
  • 182
    • 81855217383 scopus 로고    scopus 로고
    • MicroRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4
    • Liu X., Zhang Z., Sun L., Chai N., Tang S., Jin J., et al. MicroRNA-499-5p promotes cellular invasion and tumor metastasis in colorectal cancer by targeting FOXO4 and PDCD4. Carcinogenesis 2011, 32:1798-1805.
    • (2011) Carcinogenesis , vol.32 , pp. 1798-1805
    • Liu, X.1    Zhang, Z.2    Sun, L.3    Chai, N.4    Tang, S.5    Jin, J.6
  • 184
    • 79957553361 scopus 로고    scopus 로고
    • Overexpression of Dicer predicts poor survival in colorectal cancer
    • Faber C., Horst D., Hlubek F., Kirchner T. Overexpression of Dicer predicts poor survival in colorectal cancer. Eur. J. Cancer 2011, 47:1414-1419.
    • (2011) Eur. J. Cancer , vol.47 , pp. 1414-1419
    • Faber, C.1    Horst, D.2    Hlubek, F.3    Kirchner, T.4
  • 185
    • 77649275464 scopus 로고    scopus 로고
    • MiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
    • Ma L., Young J., Prabhala H., Pan E., Mestdagh P., Muth D., et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat. Cell Biol 2010, 12:247-256.
    • (2010) Nat. Cell Biol , vol.12 , pp. 247-256
    • Ma, L.1    Young, J.2    Prabhala, H.3    Pan, E.4    Mestdagh, P.5    Muth, D.6
  • 186
    • 77956269093 scopus 로고    scopus 로고
    • Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy
    • Chen Y., Zhu X., Zhang X., Liu B., Huang L. Nanoparticles modified with tumor-targeting scFv deliver siRNA and miRNA for cancer therapy. Mol. Ther 2010, 18:1650-1656.
    • (2010) Mol. Ther , vol.18 , pp. 1650-1656
    • Chen, Y.1    Zhu, X.2    Zhang, X.3    Liu, B.4    Huang, L.5
  • 187
    • 70349334281 scopus 로고    scopus 로고
    • Plasma microRNAs: a potential biomarker for colorectal cancer?
    • Schetter A.J., Harris C.C. Plasma microRNAs: a potential biomarker for colorectal cancer?. Gut 2009, 58:1318-1319.
    • (2009) Gut , vol.58 , pp. 1318-1319
    • Schetter, A.J.1    Harris, C.C.2
  • 188
    • 64949165385 scopus 로고    scopus 로고
    • In situ detection of mature microRNAs by labeled extension on ultramer templates
    • Nuovo G., Lee E.J., Lawler S., Godlewski J., Schmittgen T. In situ detection of mature microRNAs by labeled extension on ultramer templates. Biotechniques 2009, 46:115-126.
    • (2009) Biotechniques , vol.46 , pp. 115-126
    • Nuovo, G.1    Lee, E.J.2    Lawler, S.3    Godlewski, J.4    Schmittgen, T.5
  • 189
    • 77955439834 scopus 로고    scopus 로고
    • Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma
    • Schulte J.H., Marschall T., Martin M., Rosenstiel P., Mestdagh P., Schlierf S., et al. Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma. Nucleic Acids Res 2010, 38:5919-5928.
    • (2010) Nucleic Acids Res , vol.38 , pp. 5919-5928
    • Schulte, J.H.1    Marschall, T.2    Martin, M.3    Rosenstiel, P.4    Mestdagh, P.5    Schlierf, S.6


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