MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL

Carcinogenesis

Volumn 33, Issue 4, 2012, Pages 732-739

  Baraniskin, Alexander ^a,b   Birkenkamp Demtroder, Karin ^c   Maghnouj, Abdelouahid ^a   Zöllner, Hannah ^a   Munding, Johanna ^d   Klein Scory, Susanne ^b   Reinacher Schick, Anke ^a,b   Schwarte Waldhoff, Irmgard ^b   Schmiegel, Wolff ^a,b   Hahn, Stephan A ^a,b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c AARHUS UNIVERSITY HOSPITAL   (Denmark)

^d RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; DENTICLELESS PROTEIN HOMOLOG; LENTIVIRUS VECTOR; MICRORNA; MICRORNA 30A 5P; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; AGED; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CELL CULTURE; CELL CYCLE G1 PHASE; COLON CARCINOMA; FEMALE; GENE EXPRESSION; GENE TARGETING; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 84859560897     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs020     Document Type: Article

References (42)

1. Bartel, D. P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
2. Friedman, R. C. et al. (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res., 19, 92-105.
3. Ventura, A. et al. (2009) MicroRNAs and cancer: short RNAs go a long way. Cell, 136, 586-591.
4. Parkin, D. M. et al. (2002) Global cancer statistics. CA Cancer J. Clin., 55, 74-108.
5. Luo, X. et al. (2011) MicroRNA signatures: novel biomarker for colorectal cancer? Cancer Epidemiol. Biomarkers Prev., 20, 1272-1286.
6. Cummins, J. M. et al. (2006) The colorectal microRNAome. Proc. Natl Acad. Sci. USA, 103, 3687-3692.
7. Arndt, G. M. et al. (2009) Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer. BMC Cancer, 9, 374.
8. Sarver, A. L. et al. (2009) Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer, 9, 401.
9. Visone, R. et al. (2007) Specific microRNAs are downregulated in human thyroid anaplastic carcinomas. Oncogene, 26, 7590-7595.
10. Kumarswamy, R. et al. (2011) MicroRNA-30a inhibits epithelialto-mesenchymal transition by targeting snai1 and is downregulated in non-small cell lung cancer. Int. J. Cancer, 130, 2044-2053.
11. Calin, G. A. et al. (2004) MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl Acad. Sci. USA, 101, 11755-11760.
12. Li, X. et al. (2010) Survival prediction of gastric cancer by a seven-microRNA signature. Gut, 59, 579-585.
13. Martinez, I. et al. (2011) miR-29 and miR-30 regulate B-Myb expression during cellular senescence. Proc. Natl Acad. Sci. USA, 108, 522-527.
14. Kimura, S. et al. (2010) Expression of microRNAs in squamous cell carcinoma of human head and neck and the esophagus: miR-205 and miR-21 are specific markers for HNSCC and ESCC. Oncol. Rep., 23, 1625-1633.
15. Andersen, C. L. et al. (2009) Dysregulation of the transcription factors SOX4, CBFB and SMARCC1 correlates with outcome of colorectal cancer. Br. J. Cancer, 100, 511-523.
16. Birkenkamp-Demtroder, K. et al. (2007) Phosphoprotein Keratin 23 accumulates in MSS but not MSI colon cancers in vivo and impacts viability and proliferation in vitro. Mol. Oncol., 1, 181-195.
17. Munding, J. B. et al. (2011) Global microRNA expression profiling of microdissected tissues identifies miR-135b as a novel biomarker for pancreatic ductal adenocarcinoma. Int. J. Cancer, in press. doi: 10. 1002/ijc.26466.
18. Gentner, B. et al. (2009) Stable knockdown of microRNA in vivo by lentiviral vectors. Nat. Methods, 6, 63-66.
19. Abbas, T. et al. (2008) PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev., 22, 2496-2506.
20. Solly, K. et al. (2004) Application of real-time cell electronic sensing (RT-CES) technology to cell-based assays. Assay Drug Dev. Technol., 2, 363-372.
21. Kirstein, S. L. et al. (2006) Live cell quality control and utility of real-time cell electronic sensing for assay development. Assay Drug Dev. Technol., 4, 545-553.
22. Chomczynski, P. et al. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
23. Wei, J. et al. (2009) Both strands of siRNA have potential to guide posttranscriptional gene silencing in mammalian cells. PLoS One, 4, e5382.
24. Cheung, W. M. et al. (2001) Cloning and expression of a novel nuclear matrix-associated protein that is regulated during the retinoic acid-induced neuronal differentiation. J. Biol. Chem., 276, 17083-17091.
25. Li, J. et al. (2009) Identification of retinoic acid-regulated nuclear matrixassociated protein as a novel regulator of gastric cancer. Br. J. Cancer, 101, 691-698.
26. Missiaglia, E. et al. (2009) Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development. Genes Chromosomes Cancer, 48, 455-467.
27. Pan, H. et al. (2006) Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma. Cell Cycle, 5, 2676-2687.
28. Song, B. et al. (2010) Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells. Mol. Cancer, 9, 96.
29. Ueki, T. et al. (2008) Involvement of elevated expression of multiple cellcycle regulator, DTL/RAMP (denticleless/RA-regulated nuclear matrix associated protein), in the growth of breast cancer cells. Oncogene, 27, 5672-5683.
30. Timofeev, O. V. et al. (2004) Functions of p21Waf1 in norm and in stress. Mol. Biol. (Mosk.), 38, 371-385.
31. Nishitani, H. et al. (2008) CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation. J. Biol. Chem., 283, 29045-29052.
32. Deng, C. et al. (1995) Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell, 82, 675-684.
33. Banks, D. et al. (2006) L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes. Cell Cycle, 5, 1719-1729.
34. Xi, Y. et al. (2006) Prognostic values of microRNAs in colorectal cancer. Biomark. Insights, 2, 113-121.
35. Lim, L. P. et al. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature, 433, 769-773.
36. Grimson, A. et al. (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol. Cell, 27, 91-105.
37. Baek, D. et al. (2008) The impact of microRNAs on protein output. Nature, 455, 64-71.
38. Huntzinger, E. et al. (2011) Gene silencing by microRNAs: contributions of translational repression and mRNA decay. Nat. Rev. Genet., 12, 99-110.
39. Taylor, W. R. et al. (2001) Regulation of the G2/M transition by p53. Oncogene, 20, 1803-1815.
40. Enserink, J. M. et al. (2010) An overview of Cdk1-controlled targets and processes. Cell Div., 5, 11.
41. Subramanyam, D. et al. (2011) Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. Nat. Biotechnol., 29, 443-448.
42. Unsal-Kacxmaz, K. et al. (2005) Coupling of human circadian and cell cycles by the timeless protein. Mol. Cell. Biol., 25, 3109-3116.