Urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-β signaling

Differentiation

Volumn 77, Issue 1, 2009, Pages 95-102

  Li, Xiaohong ^a   Wang, Yongqing ^a   Sharif Afshar, Ali Reza ^a   Uwamariya, Consolate ^a   Yi, Andrew ^a   Ishii, Kenichiro ^a,b   Hayward, Simon W ^a   Matusik, Robert J ^a   Bhowmick, Neil A ^a  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Mesenchyme; Prostate; Stem cell; TGF ; Urogenital; Wnt

Indexed keywords

BROXURIDINE; PROTEIN WIF 1; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; MALE; MORPHOGENESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARACRINE SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROSTATE EPITHELIUM; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STEM CELL; TISSUE INDUCTION; UROTHELIUM;

ANIMALS; CELL TRANSDIFFERENTIATION; EPITHELIAL CELLS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PARACRINE COMMUNICATION; PROSTATE; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; STROMAL CELLS; TRANSFORMING GROWTH FACTOR BETA; URINARY BLADDER;

MUS;

EID: 60549100868     PISSN: 03014681     EISSN: 14320436     Source Type: Journal    
DOI: 10.1016/j.diff.2008.09.012     Document Type: Article

References (51)

1. Aoi, T., Yae, K., Nakagawa, M., Ichisaka, T., Okita, K., Takahashi, K., Chiba, T., Yamanaka, S., 2008. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science.
2. Attisano L., and Labbe E. TGFbeta and Wnt pathway cross-talk. Cancer Metastasis Rev. 23 (2004) 53-61
3. Bhowmick N.A., Chytil A., Plieth D., Gorska A.E., Dumont N., Shappell S., Washington M.K., Neilson E.G., and Moses H.L. TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science (New York, NY) 303 (2004) 848-851
4. Bierie B., Nozawa M., Renou J.P., Shillingford J.M., Morgan F., Oka T., Taketo M.M., Cardiff R.D., Miyoshi K., Wagner K.U., Robinson G.W., and Hennighausen L. Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation. Oncogene 22 (2003) 3875-3887
5. Blank U., Karlsson G., and Karlsson S. Signaling pathways governing stem-cell fate. Blood 111 (2008) 492-503
6. Blanpain C., Horsley V., and Fuchs E. Epithelial stem cells: turning over new leaves. Cell 128 (2007) 445-458
7. Boutin E.L., Battle E., and Cunha G.R. The response of female urogenital tract epithelia to mesenchymal inductors is restricted by the germ layer origin of the epithelium: prostatic inductions. Differentiation 48 (1991) 99-105
8. Boutin E.L., Sanderson R.D., Bernfield M., and Cunha G.R. Epithelial-mesenchymal interactions in uterus and vagina alter the expression of the cell surface proteoglycan, syndecan. Dev. Biol. 148 (1991) 63-74
9. Bruxvoort K.J., Charbonneau H.M., Giambernardi T.A., Goolsby J.C., Qian C.N., Zylstra C.R., Robinson D.R., Roy-Burman P., Shaw A.K., Buckner-Berghuis B.D., Sigler R.E., Resau J.H., Sullivan R., Bushman W., and Williams B.O. Inactivation of Apc in the mouse prostate causes prostate carcinoma. Cancer Res. 67 (2007) 2490-2496
10. Cheng N., Bhowmick N.A., Chytil A., Gorksa A.E., Brown K.A., Muraoka R., Arteaga C.L., Neilson E.G., Hayward S.W., and Moses H.L. Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks. Oncogene 24 (2005) 5053-5068
11. Chesire D.R., and Isaacs W.B. Beta-catenin signaling in prostate cancer: an early perspective. Endocr.-Relat. Cancer 10 (2003) 537-560
12. Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 127 (2006) 469-480
13. Cunha G.R., Fujii H., Neubauer B.L., Shannon J.M., Sawyer L., and Reese B.A. Epithelial-mesenchymal interactions in prostatic development. I. Morphological observations of prostatic induction by urogenital sinus mesenchyme in epithelium of the adult rodent urinary bladder. J. Cell Biol. 96 (1983) 1662-1670
14. Cunha G.R., Donjacour A.A., Cooke P.S., Mee S., Bigsby R.M., Higgins S.J., and Sugimura Y. The endocrinology and developmental biology of the prostate. Endocr. Rev. 8 (1987) 338-362
15. Cunha G.R., Alarid E.T., Turner T., Donjacour A.A., Boutin E.L., and Foster B.A. Normal and abnormal development of the male urogenital tract. Role of androgens, mesenchymal-epithelial interactions, and growth factors. J. Androl. 13 (1992) 465-475
16. Cunha G.R., Foster B., Thomson A., Sugimura Y., Tanji N., Tsuji M., Terada N., Finch P.W., and Donjacour A.A. Growth factors as mediators of androgen action during the development of the male urogenital tract. World J. Urol. 13 (1995) 264-276
17. Donjacour A.A., and Cunha G.R. Induction of prostatic morphology and secretion in urothelium by seminal vesicle mesenchyme. Development (Cambridge, England) 121 (1995) 2199-2207
18. Dorak M. Real-Time PCR (2006), Oxford, New York
19. Edlund S., Lee S.Y., Grimsby S., Zhang S., Aspenstrom P., Heldin C.H., and Landstrom M. Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis. Mol. Cell. Biol. 25 (2005) 1475-1488
20. Haughney P.C., Hayward S.W., Dahiya R., and Cunha G.R. Species-specific detection of growth factor gene expression in developing murine prostatic tissue. Biol. Reprod. 59 (1998) 93-99
21. Hayward S.W., and Cunha G.R. The prostate: development and physiology. Radiol. Clin. N. Am. 38 (2000) 1-14
22. Hayward S.W., Haughney P.C., Rosen M.A., Greulich K.M., Weier H.U., Dahiya R., and Cunha G.R. Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model. Differentiation 63 (1998) 131-140
23. Hayward S.W., Haughney P.C., Lopes E.S., Danielpour D., and Cunha G.R. The rat prostatic epithelial cell line NRP-152 can differentiate in vivo in response to its stromal environment. Prostate 39 (1999) 205-212
24. Kempermann G., Gast D., Kronenberg G., Yamaguchi M., and Gage F.H. Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development 130 (2003) 391-399
25. Kiel M.J., He S., Ashkenazi R., Gentry S.N., Teta M., Kushner J.A., Jackson T.L., and Morrison S.J. Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 449 (2007) 238-242
26. Kinbara H., Cunha G.R., Boutin E., Hayashi N., and Kawamura J. Evidence of stem cells in the adult prostatic epithelium based upon responsiveness to mesenchymal inductors. Prostate 29 (1996) 107-116
27. Kohn A.D., and Moon R.T. Wnt and calcium signaling: beta-catenin-independent pathways. Cell Calcium 38 (2005) 439-446
28. Kurzrock, E.A., Lieu, D.K., Degraffenried, L.A., Chan, C.W., Isseroff, R.R., 2008. Label-retaining cells of the bladder: candidate urothelial stem cells. Am. J. Physiol. Renal Physiol.
29. Labbe E., Letamendia A., and Attisano L. Association of Smads with lymphoid enhancer binding factor 1/T cell-specific factor mediates cooperative signaling by the transforming growth factor-beta and wnt pathways. Proc. Natl. Acad. Sci. USA 97 (2000) 8358-8363
30. Labbe E., Lock L., Letamendia A., Gorska A.E., Gryfe R., Gallinger S., Moses H.L., and Attisano L. Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis. Cancer Res. 67 (2007) 75-84
31. Lawson D.A., Xin L., Lukacs R., Xu Q., Cheng D., and Witte O.N. Prostate stem cells and prostate cancer. Cold Spring Harbor Symp. Quant. Biol. 70 (2005) 187-196
32. Lee C.S., Friedman J.R., Fulmer J.T., and Kaestner K.H. The initiation of liver development is dependent on Foxa transcription factors. Nature 435 (2005) 944-947
33. Letamendia A., Labbe E., and Attisano L. Transcriptional regulation by Smads: crosstalk between the TGF-beta and Wnt pathways. J. Bone Jt. Surg. Am. 83-A Suppl. 1 (2001) S31-S39
34. Massague J., and Gomis R.R. The logic of TGFbeta signaling. FEBS Lett. 580 (2006) 2811-2820
35. Nakagawa M., Koyanagi M., Tanabe K., Takahashi K., Ichisaka T., Aoi T., Okita K., Mochiduki Y., Takizawa N., and Yamanaka S. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26 (2008) 101-106
36. Oottamasathien S., Williams K., Franco O.E., Thomas J.C., Saba K., Bhowmick N.A., Staack A., Demarco R.T., Brock III J.W., Hayward S.W., and Pope J.C.t. Bladder tissue formation from cultured bladder urothelium. Dev. Dyn. 235 (2006) 2795-2801
37. Oottamasathien S., Wang Y., Williams K., Franco O.E., Wills M.L., Thomas J.C., Saba K., Sharif-Afshar A.R., Makari J.H., Bhowmick N.A., DeMarco R.T., Hipkens S., Magnuson M., Brock III J.W., Hayward S.W., Pope J.C.t., and Matusik R.J. Directed differentiation of embryonic stem cells into bladder tissue. Dev. Biol. 304 (2007) 556-566
38. Shima H., Tsuji M., Elfman F., and Cunha G.R. Development of male urogenital epithelia elicited by soluble mesenchymal factors. J. Androl. 16 (1995) 233-241
39. Staack A., Donjacour A.A., Brody J., Cunha G.R., and Carroll P. Mouse urogenital development: a practical approach. Differentiation 71 (2003) 402-413
40. Sugimura Y., Foster B.A., Hom Y.K., Lipschutz J.H., Rubin J.S., Finch P.W., Aaronson S.A., Hayashi N., Kawamura J., and Cunha G.R. Keratinocyte growth factor (KGF) can replace testosterone in the ductal branching morphogenesis of the rat ventral prostate. Int. J. Dev. Biol. 40 (1996) 941-951
41. Takahashi K., and Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006) 663-676
42. Takahashi K., Okita K., Nakagawa M., and Yamanaka S. Induction of pluripotent stem cells from fibroblast cultures. Nat. Protoc. 2 (2007) 3081-3089
43. Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., and Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007) 861-872
44. Taupin P. Protocols for studying adult neurogenesis: insights and recent developments. Regenerative Med. 2 (2007) 51-62
45. Taylor R.A., Cowin P.A., Cunha G.R., Pera M., Trounson A.O., Pedersen J., and Risbridger G.P. Formation of human prostate tissue from embryonic stem cells. Nat. Meth. 3 (2006) 179-181
46. Thomson A.A., and Cunha G.R. Prostatic growth and development are regulated by FGF10. Development 126 (1999) 3693-3701
47. Thomson A.A., Foster B.A., and Cunha G.R. Analysis of growth factor and receptor mRNA levels during development of the rat seminal vesicle and prostate. Development 124 (1997) 2431-2439
48. Thomson A.A., Timms B.G., Barton L., Cunha G.R., and Grace O.C. The role of smooth muscle in regulating prostatic induction. Development (Cambridge, England) 129 (2002) 1905-1912
49. Timme T.L., Truong L.D., Merz V.W., Krebs T., Kadmon D., Flanders K.C., Park S.H., and Thompson T.C. Mesenchymal-epithelial interactions and transforming growth factor-beta expression during mouse prostate morphogenesis. Endocrinology 134 (1994) 1039-1045
50. Voeller H.J., Truica C.I., and Gelmann E.P. Beta-catenin mutations in human prostate cancer. Cancer Res. 58 (1998) 2520-2523
51. Yan L., Han Y., He Y., Xie H., Liu J., Zhao L., Wang J., Gao L., and Fan D. Cell tracing techniques in stem cell transplantation. Stem Cell Rev. 3 (2007) 265-269