-
1
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean, M.; Fojo, T.; Bates, S. Tumour stem cells and drug resistance. Nat. Rev. Cancer 5:275-284; 2005.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
2
-
-
33644826473
-
Roots and stems: Stem cells in cancer
-
Polyak, K.; Hahn, W. C. Roots and stems: Stem cells in cancer. Nat. Med. 12:296-300; 2006.
-
(2006)
Nat. Med.
, vol.12
, pp. 296-300
-
-
Polyak, K.1
Hahn, W.C.2
-
3
-
-
33751210076
-
The cancer stem cell hypothesis: A work in progress
-
Tan, B. T.; Park, C. Y.; Ailles, L. E.; Weissman, I..L. The cancer stem cell hypothesis: A work in progress. Lab. Invest. 86:1203-1207; 2006.
-
(2006)
Lab. Invest.
, vol.86
, pp. 1203-1207
-
-
Tan, B.T.1
Park, C.Y.2
Ailles, L.E.3
Weissman, I.L.4
-
4
-
-
0029958876
-
Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
-
Goodell, M. A.; Brose, K.; Paradis, G.; Conner, A. S.; Mulligan, R. C. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J. Exp. Med. 183:1797-1806; 1996.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1797-1806
-
-
Goodell, M.A.1
Brose, K.2
Paradis, G.3
Conner, A.S.4
Mulligan, R.C.5
-
5
-
-
0034795256
-
The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
-
Zhou, S.; Schuetz, J. D.; Bunting, K. D.; Colapietro, A. M.; Sampath, J.; Morris, J. J.; Lagutina, I.; Grosveld, G. C.; Osawa, M.; Nakauchi, H.; Sorrentino, B. P. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat. Med. 7:1028-1034; 2001.
-
(2001)
Nat. Med.
, vol.7
, pp. 1028-1034
-
-
Zhou, S.1
Schuetz, J.D.2
Bunting, K.D.3
Colapietro, A.M.4
Sampath, J.5
Morris, J.J.6
Lagutina, I.7
Grosveld, G.C.8
Osawa, M.9
Nakauchi, H.10
Sorrentino, B.P.11
-
6
-
-
0037079708
-
The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors
-
Scharenberg, C. W.; Harkey, M. A.; Torok-Storb, B. The ABCG2 transporter is an efficient Hoechst 33342 efflux pump and is preferentially expressed by immature human hematopoietic progenitors. Blood 99:507-512; 2002.
-
(2002)
Blood
, vol.99
, pp. 507-512
-
-
Scharenberg, C.W.1
Harkey, M.A.2
Torok-Storb, B.3
-
7
-
-
34447292532
-
Endogenous cardiac stem cells
-
Barile, L.; Messina, E.; Giacomello, A.; Marban, E. Endogenous cardiac stem cells. Prog. Cardiovasc. Dis. 50:31-48; 2007.
-
(2007)
Prog. Cardiovasc. Dis.
, vol.50
, pp. 31-48
-
-
Barile, L.1
Messina, E.2
Giacomello, A.3
Marban, E.4
-
8
-
-
34447098515
-
Characterization of side-population cells in human normal endometrium
-
Kato, K.; Yoshimoto, M.; Kato, K.; Adachi, S.; Yamayoshi, A.; Arima, T.; Asanoma, K.; Kyo, S.; Nakahata, T.; Wake, N. Characterization of side-population cells in human normal endometrium. Hum. Reprod. 22:1214-1223; 2007.
-
(2007)
Hum. Reprod.
, vol.22
, pp. 1214-1223
-
-
Kato, K.1
Yoshimoto, M.2
Kato, K.3
Adachi, S.4
Yamayoshi, A.5
Arima, T.6
Asanoma, K.7
Kyo, S.8
Nakahata, T.9
Wake, N.10
-
9
-
-
33745924696
-
Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties
-
Chiba, T.; Kita, K.; Zheng, Y. W.; Yokosuka, O.; Saisho, H.; Iwama, A.; Nakauchi, H.; Taniguchi, H. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties. Hepatology 44:240-251; 2006.
-
(2006)
Hepatology
, vol.44
, pp. 240-251
-
-
Chiba, T.1
Kita, K.2
Zheng, Y.W.3
Yokosuka, O.4
Saisho, H.5
Iwama, A.6
Nakauchi, H.7
Taniguchi, H.8
-
10
-
-
33744985294
-
Characterization of a side population of cancer cells from human gastrointestinal system
-
Haraguchi, N.; Utsunomiya, T.; Inoue, H.; Tanaka, F.; Mimori, K.; Barnard, G. F.; Mori, M. Characterization of a side population of cancer cells from human gastrointestinal system. Stem Cells 24:506-513; 2006.
-
(2006)
Stem Cells
, vol.24
, pp. 506-513
-
-
Haraguchi, N.1
Utsunomiya, T.2
Inoue, H.3
Tanaka, F.4
Mimori, K.5
Barnard, G.F.6
Mori, M.7
-
11
-
-
4644306516
-
A distinct "side population" of cells with high drug efflux capacity in human tumor cells
-
Hirschmann-Jax, C.; Foster, A. E.; Wulf, G. G.; Nuchtern, J. G.; Jax, T. W.; Gobel, U.; Goodell, M. A.; Brenner, M. K. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc. Natl. Acad. Sci. USA 101:14228-14233; 2004.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 14228-14233
-
-
Hirschmann-Jax, C.1
Foster, A.E.2
Wulf, G.G.3
Nuchtern, J.G.4
Jax, T.W.5
Gobel, U.6
Goodell, M.A.7
Brenner, M.K.8
-
12
-
-
1642474273
-
Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line
-
Kondo, T.; Setoguchi, T.; Taga, T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc. Natl. Acad. Sci. USA 101:781-786; 2004.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 781-786
-
-
Kondo, T.1
Setoguchi, T.2
Taga, T.3
-
13
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
Croce, C. M. Causes and consequences of microRNA dysregulation in cancer. Nat. Rev. Genet. 10:704-714; 2009.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 704-714
-
-
Croce, C.M.1
-
14
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia, S.; Calin, G. A.; Liu, C. G.; Ambs, S.; Cimmino, A.; Petrocca, F.; Visone, R.; Iorio, M.; Roldo, C.; Ferracin, M.; Prueitt, R. L.; Yanaihara, N.; Lanza, G.; Scarpa, A.; Vecchione, A.; Negrini, M.; Harris, C. C.; Croce, C. M. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. USA 103:2257-2261; 2006.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
Visone, R.7
Iorio, M.8
Roldo, C.9
Ferracin, M.10
Prueitt, R.L.11
Yanaihara, N.12
Lanza, G.13
Scarpa, A.14
Vecchione, A.15
Negrini, M.16
Harris, C.C.17
Croce, C.M.18
-
15
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota, J.; Chivukula, R. R.; O'Donnell, K. A.; Wentzel, E. A.; Montgomery, C. L.; Hwang, H. W.; Chang, T. C.; Vivekanandan, P.; Torbenson, M.; Clark, K. R.; Mendell, J. R.; Mendell, J. T. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137:1005-1017; 2009.
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'Donnell, K.A.3
Wentzel, E.A.4
Montgomery, C.L.5
Hwang, H.W.6
Chang, T.C.7
Vivekanandan, P.8
Torbenson, M.9
Clark, K.R.10
Mendell, J.R.11
Mendell, J.T.12
-
16
-
-
35148886434
-
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
-
Ma, L.; Teruya-Feldstein, J.; Weinberg, R. A. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449:682-688; 2007.
-
(2007)
Nature
, vol.449
, pp. 682-688
-
-
Ma, L.1
Teruya-Feldstein, J.2
Weinberg, R.A.3
-
17
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
Tavazoie, S. F.; Alarcón, C.; Oskarsson, T.; Padua, D.; Wang, Q.; Bos, P. D.; Gerald, W. L.; Massagué, J. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 451:147-152; 2008.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcón, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
Gerald, W.L.7
Massagué, J.8
-
18
-
-
44649179826
-
Small RNAs and cancerogenesis
-
Mosc.
-
Ryazansky, S. S.; Gvozdev, V. A. Small RNAs and cancerogenesis. Biochemistry (Mosc.) 73:514-527; 2008.
-
(2008)
Biochemistry
, vol.73
, pp. 514-527
-
-
Ryazansky, S.S.1
Gvozdev, V.A.2
-
19
-
-
43949134440
-
MicroRNAs play a role in the development of human hematopoietic stem cells
-
Liao, R.; Sun, J.; Zhang, L.; Lou, G.; Chen, M.; Zhou, D.; Chen, Z.; Zhang, S. MicroRNAs play a role in the development of human hematopoietic stem cells. J. Cell. Biochem. 104:805-817; 2008.
-
(2008)
J. Cell. Biochem.
, vol.104
, pp. 805-817
-
-
Liao, R.1
Sun, J.2
Zhang, L.3
Lou, G.4
Chen, M.5
Zhou, D.6
Chen, Z.7
Zhang, S.8
-
20
-
-
36849078711
-
let-7 regulates self renewal and tumorigenicity of breast cancer cells
-
Yu, F.; Yao, H.; Zhu, P.; Zhang, X.; Pan, Q.; Gong, C.; Huang, Y.; Hu, X.; Su, F.; Lieberman, J.; Song, E. let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell 131:1109-1123; 2007.
-
(2007)
Cell
, vol.131
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
Gong, C.6
Huang, Y.7
Hu, X.8
Su, F.9
Lieberman, J.10
Song, E.11
-
21
-
-
50249173450
-
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
-
Gabriely, G.; Wurdinger, T.; Kesari, S.; Esau, C. C.; Burchard, J.; Linsley, P. S.; Krichevsky, A. M. MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol. Cell. Biol. 28:5369-5380; 2008.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 5369-5380
-
-
Gabriely, G.1
Wurdinger, T.2
Kesari, S.3
Esau, C.C.4
Burchard, J.5
Linsley, P.S.6
Krichevsky, A.M.7
-
23
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
Meng, F.; Henson, R.; Wehbe-Janek, H.; Ghoshal, K.; Jacob, S. T.; Patel, T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133:647-658; 2007.
-
(2007)
Gastroenterology
, vol.133
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
24
-
-
54249136806
-
MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
-
Papagiannakopoulos, T.; Shapiro, A.; Kosik, K. S. MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res. 68:8164-8172; 2008.
-
(2008)
Cancer Res.
, vol.68
, pp. 8164-8172
-
-
Papagiannakopoulos, T.1
Shapiro, A.2
Kosik, K.S.3
-
25
-
-
34247495591
-
miR-21-mediated tumor growth
-
Si, M. L.; Zhu, S.; Wu, H.; Lu, Z.; Wu, F.; Mo, Y. Y. miR-21-mediated tumor growth. Oncogene 26:2799-2803; 2007.
-
(2007)
Oncogene
, vol.26
, pp. 2799-2803
-
-
Si, M.L.1
Zhu, S.2
Wu, H.3
Lu, Z.4
Wu, F.5
Mo, Y.Y.6
-
26
-
-
34347266556
-
MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
-
Zhu, S.; Si, M. L.; Wu, H.; Mo, Y. Y. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J. Biol. Chem. 282:14328-14336; 2007.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14328-14336
-
-
Zhu, S.1
Si, M.L.2
Wu, H.3
Mo, Y.Y.4
-
27
-
-
38149042783
-
Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
-
Frankel, L. B.; Christoffersen, N. R.; Jacobsen, A.; Lindow, M.; Krogh, A.; Lund, A. H. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem. 283:1026-1033; 2008.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 1026-1033
-
-
Frankel, L.B.1
Christoffersen, N.R.2
Jacobsen, A.3
Lindow, M.4
Krogh, A.5
Lund, A.H.6
-
28
-
-
47549109566
-
MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
-
Lu, Z.; Liu, M.; Stribinskis, V.; Klinge, C. M.; Ramos, K. S.; Colburn, N. H.; Li, Y. MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene 27:4373-4379; 2008.
-
(2008)
Oncogene
, vol.27
, pp. 4373-4379
-
-
Lu, Z.1
Liu, M.2
Stribinskis, V.3
Klinge, C.M.4
Ramos, K.S.5
Colburn, N.H.6
Li, Y.7
-
29
-
-
4444285717
-
Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity
-
Jansen, A. P.; Camalier, C. E.; Stark, C.; Colburn, N. H. Characterization of programmed cell death 4 in multiple human cancers reveals a novel enhancer of drug sensitivity. Mol. Cancer Ther. 3:103-110; 2004.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 103-110
-
-
Jansen, A.P.1
Camalier, C.E.2
Stark, C.3
Colburn, N.H.4
-
30
-
-
22244491639
-
Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis
-
Jansen, A. P.; Camalier, C. E.; Colburn, N. H. Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis. Cancer Res. 65:6034-6041; 2005.
-
(2005)
Cancer Res.
, vol.65
, pp. 6034-6041
-
-
Jansen, A.P.1
Camalier, C.E.2
Colburn, N.H.3
-
31
-
-
42249090353
-
miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism
-
Fujita, S.; Ito, T.; Mizutani, T.; Minoguchi, S.; Yamamichi, N.; Sakurai, K.; Iba, H. miR-21 Gene expression triggered by AP-1 is sustained through a double-negative feedback mechanism. J. Mol. Biol. 378:492-504; 2008.
-
(2008)
J. Mol. Biol.
, vol.378
, pp. 492-504
-
-
Fujita, S.1
Ito, T.2
Mizutani, T.3
Minoguchi, S.4
Yamamichi, N.5
Sakurai, K.6
Iba, H.7
-
32
-
-
58149352800
-
An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation
-
Talotta, F.; Cimmino, A.; Matarazzo, M. R.; Casalino, L.; De Vita, G.; D'Esposito, M.; Di Lauro, R.; Verde, P. An autoregulatory loop mediated by miR-21 and PDCD4 controls the AP-1 activity in RAS transformation. Oncogene 28:73-84; 2009.
-
(2009)
Oncogene
, vol.28
, pp. 73-84
-
-
Talotta, F.1
Cimmino, A.2
Matarazzo, M.R.3
Casalino, L.4
De Vita, G.5
D'Esposito, M.6
Di Lauro, R.7
Verde, P.8
-
33
-
-
71049189661
-
Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export
-
Katayama, R.; Koike, S.; Sato, S.; Sugimoto, Y.; Tsuruo, T.; Fujita, N. Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. Cancer Sci. 100:2060-2068; 2009.
-
(2009)
Cancer Sci.
, vol.100
, pp. 2060-2068
-
-
Katayama, R.1
Koike, S.2
Sato, S.3
Sugimoto, Y.4
Tsuruo, T.5
Fujita, N.6
-
34
-
-
0033598712
-
Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation
-
Cmarik, J. L.; Min, H.; Hegamyer, G.; Zhan, S.; Kulesz-Martin, M.; Yoshinaga, H.; Matsuhashi, S.; Colburn, N. H. Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc. Natl. Acad. Sci. USA 96:14037-14042; 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14037-14042
-
-
Cmarik, J.L.1
Min, H.2
Hegamyer, G.3
Zhan, S.4
Kulesz-Martin, M.5
Yoshinaga, H.6
Matsuhashi, S.7
Colburn, N.H.8
-
35
-
-
70350362953
-
Hyaluronan-CD44 interaction with protein kinase Ce promotes oncogenic signaling by the stem cell marker Nanog and the Production of microrna-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotherapy resistance in breast tumor cells
-
Bourguignon, L. Y.; Spevak, C. C.; Wong, G.; Xia, W.; Gilad, E. Hyaluronan-CD44 interaction with protein kinase Ce promotes oncogenic signaling by the stem cell marker Nanog and the Production of microrna-21, leading to down-regulation of the tumor suppressor protein PDCD4, anti-apoptosis, and chemotherapy resistance in breast tumor cells. J. Biol. Chem. 284:26533-26546; 2009.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 26533-26546
-
-
Bourguignon, L.Y.1
Spevak, C.C.2
Wong, G.3
Xia, W.4
Gilad, E.5
-
36
-
-
38349190243
-
MicroRNAs modulate the chemosensitivity of tumor cells
-
Blower, P. E.; Chung, J. H.; Verducci, J. S.; Lin, S.; Park, J. K.; Dai, Z.; Liu, C. G.; Schmittgen, T. D.; Reinhold, W. C.; Croce, C. M.; Weinstein, J. N.; Sadee, W. MicroRNAs modulate the chemosensitivity of tumor cells. Mol. Cancer Ther. 7:1-9; 2008.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1-9
-
-
Blower, P.E.1
Chung, J.H.2
Verducci, J.S.3
Lin, S.4
Park, J.K.5
Dai, Z.6
Liu, C.G.7
Schmittgen, T.D.8
Reinhold, W.C.9
Croce, C.M.10
Weinstein, J.N.11
Sadee, W.12
-
37
-
-
33744521896
-
Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines
-
Meng, F.; Henson, R.; Lang, M.; Wehbe, H.; Maheshwari, S.; Mendell, J. T.; Jiang, J.; Schmittgen, T. D.; Patel, T. Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines. Gastroenterology 130:2113-2129; 2006.
-
(2006)
Gastroenterology
, vol.130
, pp. 2113-2129
-
-
Meng, F.1
Henson, R.2
Lang, M.3
Wehbe, H.4
Maheshwari, S.5
Mendell, J.T.6
Jiang, J.7
Schmittgen, T.D.8
Patel, T.9
|