MicroRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells

Biochemical and Biophysical Research Communications

Volumn 400, Issue 2, 2010, Pages 236-240

  Liu, Lin ^a   Chen, Lin ^a   Xu, Yingxin ^a   Li, Rong ^a   Du, Xiaohui ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Apoptosis; Bcl 2; Colorectal cancer; MicroRNA; MiR 195

Indexed keywords

BETA ACTIN; MICRORNA; MICRORNA 195; PROTEIN BCL 2; UNCLASSIFIED DRUG; MIRN195 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER TISSUE; CARCINOGENICITY; CELL VIABILITY; COLON CARCINOGENESIS; COLORECTAL CANCER; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; UPREGULATION; ADULT; AGED; CELL TRANSFORMATION; COLORECTAL TUMOR; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROTO ONCOGENE; TUMOR SUPPRESSOR GENE;

ADULT; AGED; APOPTOSIS; CELL TRANSFORMATION, NEOPLASTIC; COLORECTAL NEOPLASMS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-2; GENES, TUMOR SUPPRESSOR; HUMANS; MALE; MICRORNAS; MIDDLE AGED;

EID: 77956790226     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.08.046     Document Type: Article

References (30)

1. Griffiths-Jones S., Grocock R.J., van Dongen S., Bateman A., Enright A.J. miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006, 34:140-144.
2. Bushati N., Cohen S.M. microRNA functions. Annu. Rev. Cell Dev. Biol. 2007, 23:175-205.
3. Liu W., Mao S.Y., Zhu W.Y. Impact of tiny miRNAs on cancers. World J. Gastroenterol. 2007, 13:497-502.
4. Garzon R., Calin G.A., Croce C.M. MicroRNAs in cancer. Annu. Rev. Med. 2009, 60:167-179.
5. Weitz J., Koch M., Debus J., Hohler T., Galle P.R., Buchler M.W. Colorectal cancer. Lancet 2005, 365:153-165.
6. Slaby O., Svoboda M., Michalek J., Vyzula R. MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol. Cancer 2009, 8:102.
7. Schimanski C.C., Frerichs K., Rahman F., Berger M., Lang H., Galle P.R., Moehler M., Gockel I. High miR-196a levels promote the oncogenic phenotype of colorectal cancer cells. World J. Gastroenterol. 2009, 15:2089-2096.
8. Bandres E., Cubedo E., Agirre X., Malumbres R., Zarate R., Ramirez N., Abajo A., Navarro A., Moreno I., Monzo M., Garcia-Foncillas J. Identification by real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues. Mol. Cancer 2006, 5:29.
9. Volinia S., Calin G.A., Liu C.G., Ambs S., Cimmino A., Petrocca F., Visone R., Iorio M., Roldo C., Ferracin M., Prueitt R.L., Yanaihara N., Lanza G., Scarpa A., Vecchione A., Negrini M., Harris C.C., Croce C.M. A micro-RNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. 2006, 103:2257-2261.
10. Motoyama K., Inoue H., Takatsuno Y., Tanaka F., Mimori K., Uetake H., Sugihara K., Mori M. Over- and under-expressed microRNAs in human colorectal cancer. Int. J. Oncol. 2009, 34:1069-1075.
11. Schetter A.J., Leung S.Y., Sohn J.J., Zanetti K.A., Bowman E.D., Yanaihara N., Yuen S.T., Chan T.L., Kwong D.L., Au G.K., Liu C.G., Calin G.A., Croce C.M., Harris C.C. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008, 299:425-436.
12. Monzo M., Navarro A., Bandres E., Artells R., Moreno I., Gel B., Ibeas R., Moreno J., Martinez F., Diaz T., Martinez A., Balagué O., Garcia-Foncillas J. Overlapping expression of microRNAs in human embryonic colon and colorectal cancer. Cell Res. 2008, 18:823-833.
13. Strillacci A., Griffoni C., Sansone P., Paterini P., Piazzi G., Lazzarini G., Spisni E., Pantaleo M.A., Biasco G., Tomasi V. MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells. Exp. Cell Res. 2009, 315:1439-1447.
14. Heneghan H.M., Miller N., Lowery A.J., Sweeney K.J., Newell J., Kerin M.J. Circulating microRNAs as novel minimally invasive biomarkers for breast cancer. Ann. Surg. 2010, 251:499-505.
15. Zhang H., Su S.B., Zhou Q.M., Lu Y.Y. Differential expression profiles of microRNAs between breast cancer cells and mammary epithelial cells. Ai Zheng 2009, 28:493-499.
16. Zanette D.L., Rivadavia F., Molfetta G.A., Barbuzano F.G., Proto-Siqueira R., Silva-Jr W.A., Falcão R.P., Zago M.A. MiRNA expression profiles in chronic lymphocytic and acute lymphocytic leukemia. Braz. J. Med. Biol. Res. 2007, 40:1435-1440.
17. Xu T., Zhu Y., Xiong Y., Ge Y.Y., Yun J.P., Zhuang S.M. MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells. Hepatology 2009, 50:113-121.
18. Soon P.S., Tacon L.J., Gill A.J., Bambach C.P., Sywak M.S., Campbell P.R., Yeh M.W., Wong S.G., Clifton-Bligh R.J., Robinson B.G., Sidhu S.B. MiR-195 and miR-483-5p identified as predictors of poor prognosis in adrenocortical cancer. Clin. Cancer Res. 2009, 15:7684-7692.
19. Wong T.S., Liu X.B., Wong B.Y., Ng R.W., Yuen A.P., Wei W.I. Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin. Cancer Res. 2008, 14:2588-2592.
20. Nie J., Xie P., Liu L., Xing G., Chang Z., Yin Y., Tian C., He F., Zhang L. Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2. J. Biol. Chem. 2010, 285:22818-22830.
21. Nie J., Liu L., Wu M., Xing G., He S., Yin Y., Tian C., He F., Zhang L. HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradation. FEBS Lett. 2010, 584:3005-3012.
22. Hou J., Wang P., Lin L., Liu X., Ma F., An H., Wang Z., Cao X. MicroRNA-146a feedback inhibits RIG-I-dependent type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2. J. Immunol. 2009, 183:2150-2158.
23. -ΔΔCt method. Methods 2001, 25:402-408.
24. Su H., Yang J., Xu T., Huang J., Xu L., Yuan Y., Zhuang S. MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity. Cancer Res. 2009, 69:1135-1142.
25. Xiong Y., Fang J., Yun J., Yang J., Zhang Y., Jia W., Zhuang S. Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology 2009, 51:836-845.
26. Bhatavdekar J.M., Patel D.D., Ghosh N., Chikhlikar P.R., Trivedi T.I., Suthar T.P., Doctor S.S., Shah N.G., Balar D.B. Coexpression of Bcl-2, c-Myc, and p53 oncoproteins as prognostic discriminants in patients with colorectal carcinoma. Dis. Colon Rectum. 1997, 40:785-790.
27. Merritt A.J., Potten C.S., Watson A.J., Loh D.Y., Nakayama K., Hickman J.A. Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia. J. Cell Sci. 1995, 108:2261-2271.
28. Esteller M. Epigenetics in cancer. N. Engl. J. Med. 2008, 358:1148-1159.
29. Mishra P.J., Merlino G. MicroRNA reexpression as differentiation therapy in cancer. J. Clin. Invest. 2009, 119:2119-2123.
30. Selbach M., Schwanhäusser B., Thierfelder N., Fang Z., Khanin R., Rajewsky N. Widespread changes in protein synthesis induced by microRNAs. Nature 2008, 455:58-63.