메뉴 건너뛰기




Volumn 10, Issue 3, 2015, Pages

NLRP3 Mediates NF-κB activation and cytokine induction in microbially induced and sterile inflammation

Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; CARRIER PROTEIN; CYTOKINE; NLRP3 PROTEIN, HUMAN; URIC ACID;

EID: 84924353419     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0119179     Document Type: Article
Times cited : (55)

References (43)
  • 1
    • 64049111768 scopus 로고    scopus 로고
    • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
    • PMID: 19362020
    • Allen IC, Scull MA, Moore CB, Holl EK, McElvania-TeKippe E, Taxman DJ, et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity. 2009; 30:556-565. doi: 10.1016/j.immuni.2009.02.005 PMID: 19362020
    • (2009) Immunity. , vol.30 , pp. 556-565
    • Allen, I.C.1    Scull, M.A.2    Moore, C.B.3    Holl, E.K.4    McElvania-TeKippe, E.5    Taxman, D.J.6
  • 2
    • 70449448992 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASCcontaining inflammasome
    • PMID: 19414800
    • Duncan JA, Gao X, Huang MT, O'Connor BP, Thomas CE, Willingham SB, et al. Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASCcontaining inflammasome. J Immunol. 2009; 182:6460-6469. doi: 10.4049/jimmunol.0802696 PMID: 19414800
    • (2009) J Immunol. , vol.182 , pp. 6460-6469
    • Duncan, J.A.1    Gao, X.2    Huang, M.T.3    O'Connor, B.P.4    Thomas, C.E.5    Willingham, S.B.6
  • 3
    • 67349271142 scopus 로고    scopus 로고
    • Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
    • PMID: 19339971
    • Gross O, Poeck H, Bscheider M, Dostert C, Hannesschlager N, Endres S, et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature. 2009; 459:433-436. doi: 10. 1038/nature07965 PMID: 19339971
    • (2009) Nature , vol.459 , pp. 433-436
    • Gross, O.1    Poeck, H.2    Bscheider, M.3    Dostert, C.4    Hannesschlager, N.5    Endres, S.6
  • 4
    • 77749270973 scopus 로고    scopus 로고
    • Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappaB activation but proceeds independently of TLR signaling and P2X7 receptor
    • PMID: 19812205
    • Harder J, Franchi L, Munoz-Planillo R, Park JH, Reimer T, Nunez G. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappaB activation but proceeds independently of TLR signaling and P2X7 receptor. J Immunol. 2009; 183:5823-5829. doi: 10.4049/ jimmunol.0900444 PMID: 19812205
    • (2009) J Immunol. , vol.183 , pp. 5823-5829
    • Harder, J.1    Franchi, L.2    Munoz-Planillo, R.3    Park, J.H.4    Reimer, T.5    Nunez, G.6
  • 5
    • 69149087051 scopus 로고    scopus 로고
    • NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation
    • PMID: 19541630
    • Hruz P, Zinkernagel AS, Jenikova G, Botwin GJ, Hugot JP, Karin M, et al. NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation. Proc Natl Acad Sci U S A. 2009; 106:12873-12878. doi: 10.1073/pnas.0904958106 PMID: 19541630
    • (2009) Proc Natl Acad Sci u S A. , vol.106 , pp. 12873-12878
    • Hruz, P.1    Zinkernagel, A.S.2    Jenikova, G.3    Botwin, G.J.4    Hugot, J.P.5    Karin, M.6
  • 6
    • 64049096334 scopus 로고    scopus 로고
    • The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
    • PMID: 19362023
    • Thomas PG, Dash P, Aldridge JR Jr, Ellebedy AH, Reynolds C, Funk AJ, et al. The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity. 2009; 30:566-575. doi: 10.1016/j.immuni.2009.02.006 PMID: 19362023
    • (2009) Immunity. , vol.30 , pp. 566-575
    • Thomas, P.G.1    Dash, P.2    Aldridge, J.R.3    Ellebedy, A.H.4    Reynolds, C.5    Funk, A.J.6
  • 7
    • 77954521853 scopus 로고    scopus 로고
    • Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling
    • PMID: 20348425
    • Toma C, Higa N, Koizumi Y, Nakasone N, Ogura Y, McCoy AJ, et al. Pathogenic Vibrio activate NLRP3 inflammasome via cytotoxins and TLR/nucleotide-binding oligomerization domain-mediated NF-kappa B signaling. J immunol. 2010; 184:5287-5297. doi: 10.4049/jimmunol.0903536 PMID: 20348425
    • (2010) J Immunol. , vol.184 , pp. 5287-5297
    • Toma, C.1    Higa, N.2    Koizumi, Y.3    Nakasone, N.4    Ogura, Y.5    McCoy, A.J.6
  • 8
    • 77749304033 scopus 로고    scopus 로고
    • Sterile inflammatory responses mediated by the NLRP3 inflammasome
    • PMID: 20201012
    • Cassel SL, Sutterwala FS. Sterile inflammatory responses mediated by the NLRP3 inflammasome. Eur J Immunol. 2010; 40:607-611. doi: 10.1002/eji.200940207 PMID: 20201012
    • (2010) Eur J Immunol. , vol.40 , pp. 607-611
    • Cassel, S.L.1    Sutterwala, F.S.2
  • 9
    • 78649526394 scopus 로고    scopus 로고
    • Sterile inflammation: Sensing and reacting to damage
    • PMID: 21088683
    • Chen GY, Nunez G. Sterile inflammation: sensing and reacting to damage. Nat Rev Immunol. 2010; 10:826-837. doi: 10.1038/nri2873 PMID: 21088683
    • (2010) Nat Rev Immunol. , vol.10 , pp. 826-837
    • Chen, G.Y.1    Nunez, G.2
  • 10
    • 77951800951 scopus 로고    scopus 로고
    • NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
    • PMID: 20428172
    • Duewell P, Kono H, Rayner KJ, Sirois CM, Vladimer G, Bauernfeind FG, et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature. 2010; 464:1357-1361. doi: 10.1038/nature08938 PMID: 20428172
    • (2010) Nature. , vol.464 , pp. 1357-1361
    • Duewell, P.1    Kono, H.2    Rayner, K.J.3    Sirois, C.M.4    Vladimer, G.5    Bauernfeind, F.G.6
  • 11
    • 47849085872 scopus 로고    scopus 로고
    • The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
    • PMID: 18604209
    • Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta. Nat Immunol. 2008; 9:857-865. doi: 10.1038/ni.1636 PMID: 18604209
    • (2008) Nat Immunol. , vol.9 , pp. 857-865
    • Halle, A.1    Hornung, V.2    Petzold, G.C.3    Stewart, C.R.4    Monks, B.G.5    Reinheckel, T.6
  • 12
    • 32944462834 scopus 로고    scopus 로고
    • Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
    • PMID: 16407888
    • Kanneganti TD, Ozoren N, Body-Malapel M, Amer A, Park JH, Franchi L, et al. Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3. Nature. 2006; 440:233-236. PMID: 16407888
    • (2006) Nature. , vol.440 , pp. 233-236
    • Kanneganti, T.D.1    Ozoren, N.2    Body-Malapel, M.3    Amer, A.4    Park, J.H.5    Franchi, L.6
  • 14
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • PMID: 16407889
    • Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature. 2006; 440:237-241. PMID: 16407889
    • (2006) Nature. , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 15
    • 77955356552 scopus 로고    scopus 로고
    • Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: A novel link between cholesterol metabolism and inflammation
    • PMID: 20668705
    • Rajamaki K, Lappalainen J, Oorni K, Valimaki E, Matikainen S, Kovanen PT, et al. Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. PLoS One. 2010; 5:e11765. doi: 10.1371/journal.pone.0011765 PMID: 20668705
    • (2010) PLoS One. , vol.5 , pp. e11765
    • Rajamaki, K.1    Lappalainen, J.2    Oorni, K.3    Valimaki, E.4    Matikainen, S.5    Kovanen, P.T.6
  • 16
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • PMID: 18403674
    • Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science. 2008; 320:674-677. doi: 10. 1126/science.1156995 PMID: 18403674
    • (2008) Science , vol.320 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 17
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • PMID: 18604214
    • Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol. 2008; 9:847-856. doi: 10.1038/ni.1631 PMID: 18604214
    • (2008) Nat Immunol. , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3    Samstad, E.O.4    Kono, H.5    Rock, K.L.6
  • 18
    • 79953219478 scopus 로고    scopus 로고
    • The genetic and molecular basis of inflammasome-mediated disease
    • PMID: 21296874
    • Hoffman HM, Brydges SD. The genetic and molecular basis of inflammasome-mediated disease. J Biol Chem. 2011; 286:10889-10896. doi: 10.1074/jbc.R110.135491 PMID: 21296874
    • (2011) J Biol Chem. , vol.286 , pp. 10889-10896
    • Hoffman, H.M.1    Brydges, S.D.2
  • 19
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1betaprocessing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • PMID: 15030775
    • Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1betaprocessing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity. 2004; 20:319-325. PMID: 15030775
    • (2004) Immunity. , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 21
    • 77249118801 scopus 로고    scopus 로고
    • The inflammasomes: Mechanisms of activation and function
    • Latz E. The inflammasomes: mechanisms of activation and function. Curr. 2010; 22:28-33.
    • (2010) Curr. , vol.22 , pp. 28-33
    • Latz, E.1
  • 22
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • PMID: 20303873
    • Schroder K, Tschopp J. The inflammasomes. Cell. 2010; 140:821-832. doi: 10.1016/j.cell.2010.01.040PMID: 20303873
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 23
    • 20444442787 scopus 로고    scopus 로고
    • PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion
    • PMID: 15817483
    • Kinoshita T, Wang Y, Hasegawa M, Imamura R, Suda T. PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem. 2005; 280:21720-21725. PMID: 15817483
    • (2005) J Biol Chem. , vol.280 , pp. 21720-21725
    • Kinoshita, T.1    Wang, Y.2    Hasegawa, M.3    Imamura, R.4    Suda, T.5
  • 24
    • 0037192793 scopus 로고    scopus 로고
    • PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B
    • PMID: 11786556
    • Manji GA, Wang L, Geddes BJ, Brown M, Merriam S, Al-Garawi A, et al. PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B. J Biol Chem. 2002; 277:11570-11575. PMID: 11786556
    • (2002) J Biol Chem. , vol.277 , pp. 11570-11575
    • Manji, G.A.1    Wang, L.2    Geddes, B.J.3    Brown, M.4    Merriam, S.5    Al-Garawi, A.6
  • 25
    • 33749153819 scopus 로고    scopus 로고
    • Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways
    • PMID: 16982856
    • Taxman DJ, Zhang J, Champagne C, Bergstralh DT, Iocca HA, Lich JD, et al. Cutting edge: ASC mediates the induction of multiple cytokines by Porphyromonas gingivalis via caspase-1-dependent and -independent pathways. J Immunol. 2006; 177:4252-4256. PMID: 16982856
    • (2006) J Immunol. , vol.177 , pp. 4252-4256
    • Taxman, D.J.1    Zhang, J.2    Champagne, C.3    Bergstralh, D.T.4    Iocca, H.A.5    Lich, J.D.6
  • 26
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
    • PMID: 4179068
    • Boyum A. Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl. 1968; 97:77-89. PMID: 4179068
    • (1968) Scand J Clin Lab Invest Suppl. , vol.97 , pp. 77-89
    • Boyum, A.1
  • 27
    • 77954842857 scopus 로고    scopus 로고
    • Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication
    • PMID: 20500518
    • Motani K, Kawase K, Imamura R, Kinoshita T, Kushiyama H, Suda T. Activation of ASC induces apoptosis or necrosis, depending on the cell type, and causes tumor eradication. Cancer Sci. 2010; 101:1822-1827. doi: 10.1111/j.1349-7006.2010.01610.x PMID: 20500518
    • (2010) Cancer Sci. , vol.101 , pp. 1822-1827
    • Motani, K.1    Kawase, K.2    Imamura, R.3    Kinoshita, T.4    Kushiyama, H.5    Suda, T.6
  • 28
    • 8744297444 scopus 로고    scopus 로고
    • Fas ligand induces cellautonomous NF-kappaB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-alpha
    • PMID: 15337758
    • Imamura R, Konaka K, Matsumoto N, Hasegawa M, Fukui M, Mukaida N, et al. Fas ligand induces cellautonomous NF-kappaB activation and interleukin-8 production by a mechanism distinct from that of tumor necrosis factor-alpha. J Biol Chem. 2004; 279:46415-46423. PMID: 15337758
    • (2004) J Biol Chem. , vol.279 , pp. 46415-46423
    • Imamura, R.1    Konaka, K.2    Matsumoto, N.3    Hasegawa, M.4    Fukui, M.5    Mukaida, N.6
  • 29
    • 77649179433 scopus 로고    scopus 로고
    • NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production?
    • PMID: 20168318
    • Tschopp J, Schroder K. NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production? Nat Rev Immunol. 2010; 10:210-215. doi: 10.1038/nri2725 PMID: 20168318
    • (2010) Nat Rev Immunol. , vol.10 , pp. 210-215
    • Tschopp, J.1    Schroder, K.2
  • 30
    • 77749304034 scopus 로고    scopus 로고
    • Critical functions of priming and lysosomal damage for NLRP3 activation
    • PMID: 20201015
    • Hornung V, Latz E. Critical functions of priming and lysosomal damage for NLRP3 activation. Eur J Immunol. 2010; 40:620-623. doi: 10.1002/eji.200940185 PMID: 20201015
    • (2010) Eur J Immunol. , vol.40 , pp. 620-623
    • Hornung, V.1    Latz, E.2
  • 31
    • 34548386663 scopus 로고    scopus 로고
    • Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/ NLRP3 and ASC
    • PMID: 18005730
    • Willingham SB, Bergstralh DT, O'Connor W, Morrison AC, Taxman DJ, Duncan JA, et al. Microbial pathogen-induced necrotic cell death mediated by the inflammasome components CIAS1/cryopyrin/ NLRP3 and ASC. Cell Host Microbe. 2007; 2:147-159. PMID: 18005730
    • (2007) Cell Host Microbe. , vol.2 , pp. 147-159
    • Willingham, S.B.1    Bergstralh, D.T.2    O'Connor, W.3    Morrison, A.C.4    Taxman, D.J.5    Duncan, J.A.6
  • 32
    • 23644456849 scopus 로고    scopus 로고
    • The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages
    • PMID: 16025156
    • Schaefer L, Babelova A, Kiss E, Hausser HJ, Baliova M, Krzyzankova M, et al. The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest. 2005; 115:2223-2233. PMID: 16025156
    • (2005) J Clin Invest. , vol.115 , pp. 2223-2233
    • Schaefer, L.1    Babelova, A.2    Kiss, E.3    Hausser, H.J.4    Baliova, M.5    Krzyzankova, M.6
  • 33
    • 30744462300 scopus 로고    scopus 로고
    • Regulation of lung injury and repair by Toll-like receptors and hyaluronan
    • PMID: 16244651
    • Jiang D, Liang J, Fan J, Yu S, Chen S, Luo Y, et al. Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med. 2005; 11:1173-1179. PMID: 16244651
    • (2005) Nat Med. , vol.11 , pp. 1173-1179
    • Jiang, D.1    Liang, J.2    Fan, J.3    Yu, S.4    Chen, S.5    Luo, Y.6
  • 34
    • 69949175486 scopus 로고    scopus 로고
    • Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors
    • PMID: 19605353
    • Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, et al. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem. 2009; 284:24035-24048. doi: 10.1074/jbc.M109.014266 PMID: 19605353
    • (2009) J Biol Chem. , vol.284 , pp. 24035-24048
    • Babelova, A.1    Moreth, K.2    Tsalastra-Greul, W.3    Zeng-Brouwers, J.4    Eickelberg, O.5    Young, M.F.6
  • 35
    • 67649831360 scopus 로고    scopus 로고
    • NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury
    • PMID: 19258328
    • Yamasaki K, Muto J, Taylor KR, Cogen AL, Audish D, Bertin J, et al. NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem. 2009; 284:12762-12771. doi: 10.1074/jbc.M806084200 PMID: 19258328
    • (2009) J Biol Chem. , vol.284 , pp. 12762-12771
    • Yamasaki, K.1    Muto, J.2    Taylor, K.R.3    Cogen, A.L.4    Audish, D.5    Bertin, J.6
  • 36
    • 79957624096 scopus 로고    scopus 로고
    • The NLR adaptor ASC/pycard regulates DUSP10, MAP kinase (MAPK) and chemokine induction independent of the inflammasome
    • PMID: 21487011
    • Taxman DJ, Holley-Guthrie EA, Huang MT, Moore CB, Bergstralh DT, Allen IC, et al. The NLR adaptor ASC/pycard regulates DUSP10, MAP kinase (MAPK) and chemokine induction independent of the inflammasome. J Biol Chem. 2011; 286:19605-19616. doi: 10.1074/jbc.M111.221077 PMID: 21487011
    • (2011) J Biol Chem. , vol.286 , pp. 19605-19616
    • Taxman, D.J.1    Holley-Guthrie, E.A.2    Huang, M.T.3    Moore, C.B.4    Bergstralh, D.T.5    Allen, I.C.6
  • 37
    • 17644417155 scopus 로고    scopus 로고
    • ASC-mediated NF-kappaB activation leading to interleukin-8 production requires caspase-8 and is inhibited by CLARP
    • PMID: 15701651
    • Hasegawa M, Imamura R, Kinoshita T, Matsumoto N, Masumoto J, Inohara N, et al. ASC-mediated NF-kappaB activation leading to interleukin-8 production requires caspase-8 and is inhibited by CLARP. J Biol Chem. 2005; 280:15122-15130. PMID: 15701651
    • (2005) J Biol Chem. , vol.280 , pp. 15122-15130
    • Hasegawa, M.1    Imamura, R.2    Kinoshita, T.3    Matsumoto, N.4    Masumoto, J.5    Inohara, N.6
  • 38
    • 84876237736 scopus 로고    scopus 로고
    • The Adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation
    • PMID: 23582325
    • Subramanian N, Natarajan K, Clatworthy MR, Wang Z, Germain RN. The Adaptor MAVS Promotes NLRP3 Mitochondrial Localization and Inflammasome Activation. Cell. 2013; 153:348-361. doi: 10. 1016/j.cell.2013.02.054 PMID: 23582325
    • (2013) Cell , vol.153 , pp. 348-361
    • Subramanian, N.1    Natarajan, K.2    Clatworthy, M.R.3    Wang, Z.4    Germain, R.N.5
  • 39
    • 84865242147 scopus 로고    scopus 로고
    • ASC-dependent RIP2 kinase regulates reduced PGE2 production in chronic periodontitis
    • PMID: 22828789
    • Taxman DJ, Lei Y, Zhang S, Holley-Guthrie E, Offenbacher S, Ting JP. ASC-dependent RIP2 kinase regulates reduced PGE2 production in chronic periodontitis. J Dent Res. 2012; 91:877-882. doi: 10. 1177/0022034512454541 PMID: 22828789
    • (2012) J Dent Res. , vol.91 , pp. 877-882
    • Taxman, D.J.1    Lei, Y.2    Zhang, S.3    Holley-Guthrie, E.4    Offenbacher, S.5    Ting, J.P.6
  • 40
    • 84885437002 scopus 로고    scopus 로고
    • The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity
    • PMID: 24048902
    • Park S, Juliana C, Hong S, Datta P, Hwang I, Fernandes-Alnemri T, et al. The mitochondrial antiviral protein MAVS associates with NLRP3 and regulates its inflammasome activity. J Immunol. 2013; 191:4358-4366. doi: 10.4049/jimmunol.1301170 PMID: 24048902
    • (2013) J Immunol. , vol.191 , pp. 4358-4366
    • Park, S.1    Juliana, C.2    Hong, S.3    Datta, P.4    Hwang, I.5    Fernandes-Alnemri, T.6
  • 41
    • 78650659200 scopus 로고    scopus 로고
    • An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury
    • PMID: 20962258
    • Shigeoka AA, Mueller JL, Kambo A, Mathison JC, King AJ, Hall WF, et al. An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury. J Immunol. 2010; 185:6277-6285. doi: 10.4049/jimmunol.1002330 PMID: 20962258
    • (2010) J Immunol. , vol.185 , pp. 6277-6285
    • Shigeoka, A.A.1    Mueller, J.L.2    Kambo, A.3    Mathison, J.C.4    King, A.J.5    Hall, W.F.6
  • 42
    • 84872737232 scopus 로고    scopus 로고
    • Inflammasome-independent NLRP3 augments TGF-beta signaling in kidney epithelium
    • PMID: 23264657
    • Wang W, Wang X, Chun J, Vilaysane A, Clark S, French G, et al. Inflammasome-Independent NLRP3 Augments TGF-beta Signaling in Kidney Epithelium. J Immunol. 2012; 190:1239-1249. doi: 10.4049/ jimmunol.1201959 PMID: 23264657
    • (2012) J Immunol. , vol.190 , pp. 1239-1249
    • Wang, W.1    Wang, X.2    Chun, J.3    Vilaysane, A.4    Clark, S.5    French, G.6
  • 43
    • 84864403686 scopus 로고    scopus 로고
    • Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling
    • PMID: 22848390
    • Zuurbier CJ, Jong WM, Eerbeek O, Koeman A, Pulskens WP, Butter LM, et al. Deletion of the innate immune NLRP3 receptor abolishes cardiac ischemic preconditioning and is associated with decreased Il-6/STAT3 signaling. PLoS One. 2012; 7:e40643. doi: 10.1371/journal.pone.0040643 PMID: 22848390
    • (2012) PLoS One. , vol.7 , pp. e40643
    • Zuurbier, C.J.1    Jong, W.M.2    Eerbeek, O.3    Koeman, A.4    Pulskens, W.P.5    Butter, L.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.