메뉴 건너뛰기




Volumn 4, Issue 9, 2014, Pages

MYC cofactors: Molecular switches controlling diverse biological outcomes

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CYCLIN G2; HISTONE DEACETYLASE 1; HISTONE H4; INTEGRIN; MYC PROTEIN; NEUROTROPHIN RECEPTOR P75; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; PROTEIN KINASE PIM 1; RNA POLYMERASE;

EID: 84923832213     PISSN: None     EISSN: 21571422     Source Type: Journal    
DOI: 10.1101/cshperspect.a014399     Document Type: Article
Times cited : (49)

References (191)
  • 1
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation byMyc proteins
    • Adhikary S, Eilers M. 2005. Transcriptional regulation and transformation byMyc proteins. Nat Rev Mol Cell Biol 6: 635–645.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 2
    • 78650336901 scopus 로고    scopus 로고
    • Proteomic profiling of Myc-associated proteins
    • Agrawal P, Yu K, Salomon AR, Sedivy JM. 2010. Proteomic profiling of Myc-associated proteins. Cell Cycle 9: 4908–4921.
    • (2010) Cell Cycle , vol.9 , pp. 4908-4921
    • Agrawal, P.1    Yu, K.2    Salomon, A.R.3    Sedivy, J.M.4
  • 5
    • 33748199553 scopus 로고    scopus 로고
    • Conditional transgenic models define how MYC initiates and maintains tumorigenesis
    • Arvanitis C, Felsher DW. 2006.Conditional transgenic models define how MYC initiates and maintains tumorigenesis. Semin Cancer Biol 16: 313–317.
    • (2006) Semin Cancer Biol , vol.16 , pp. 313-317
    • Arvanitis, C.1    Felsher, D.W.2
  • 6
    • 0026776693 scopus 로고
    • Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells
    • Barrett J, Birrer MJ, Kato GJ, Dosaka-Akita H, Dang CV. 1992. Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells. Mol Cell Biol 12: 3130–3137.
    • (1992) Mol Cell Biol , vol.12 , pp. 3130-3137
    • Barrett, J.1    Birrer, M.J.2    Kato, G.J.3    Dosaka-Akita, H.4    Dang, C.V.5
  • 7
    • 27644514167 scopus 로고    scopus 로고
    • Human c-Myc isoforms differentially regulate cell growth and apoptosis in Drosophila melanogaster
    • Benassayag C, Montero L, Colombie N, Gallant P, Cribbs D, Morello D. 2005. Human c-Myc isoforms differentially regulate cell growth and apoptosis in Drosophila melanogaster. Mol Cell Biol 25: 9897–9909.
    • (2005) Mol Cell Biol , vol.25 , pp. 9897-9909
    • Benassayag, C.1    Montero, L.2    Colombie, N.3    Gallant, P.4    Cribbs, D.5    Morello, D.6
  • 10
    • 79551660279 scopus 로고    scopus 로고
    • Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism
    • Boone DN, Qi Y, Li Z, Hann SR. 2011. Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism. Proc Natl Acad Sci 108: 632–637.
    • (2011) Proc Natl Acad Sci , vol.108 , pp. 632-637
    • Boone, D.N.1    Qi, Y.2    Li, Z.3    Hann, S.R.4
  • 11
    • 0035881691 scopus 로고    scopus 로고
    • Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter
    • Bouchard C, Dittrich O, Kiermaier A, Dohmann K, Menkel A, Eilers M, Luscher B. 2001. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev 15: 2042–2047.
    • (2001) Genes Dev , vol.15 , pp. 2042-2047
    • Bouchard, C.1    Dittrich, O.2    Kiermaier, A.3    Dohmann, K.4    Menkel, A.5    Eilers, M.6    Luscher, B.7
  • 12
    • 3543028648 scopus 로고    scopus 로고
    • Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins
    • Bouchard C, Marquardt J, Bras A, Medema RH, Eilers M. 2004. Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins. EMBO J 23: 2830–2840.
    • (2004) EMBO J , vol.23 , pp. 2830-2840
    • Bouchard, C.1    Marquardt, J.2    Bras, A.3    Medema, R.H.4    Eilers, M.5
  • 14
    • 0032535177 scopus 로고    scopus 로고
    • C-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets
    • Bush A, Mateyak M, Dugan K, Obaya A, Adachi S, Sedivy J, Cole M. 1998. c-myc null cells misregulate cad and gadd45 but not other proposed c-Myc targets. Genes Dev 12: 3797–3802.
    • (1998) Genes Dev , vol.12 , pp. 3797-3802
    • Bush, A.1    Mateyak, M.2    Dugan, K.3    Obaya, A.4    Adachi, S.5    Sedivy, J.6    Cole, M.7
  • 16
    • 79955513100 scopus 로고    scopus 로고
    • Aberrations of EZH2 in cancer
    • Chase A, Cross NC. 2011. Aberrations of EZH2 in cancer. Clin Cancer Res 17: 2613–2618.
    • (2011) Clin Cancer Res , vol.17 , pp. 2613-2618
    • Chase, A.1    Cross, N.C.2
  • 17
    • 77956820491 scopus 로고    scopus 로고
    • Reactivating the ARF-p53 axis in AML cells by targeting ULF
    • Chen D, Yoon JB, Gu W. 2010. Reactivating the ARF-p53 axis in AML cells by targeting ULF. Cell Cycle 9: 2946–2951.
    • (2010) Cell Cycle , vol.9 , pp. 2946-2951
    • Chen, D.1    Yoon, J.B.2    Gu, W.3
  • 18
    • 84885409944 scopus 로고    scopus 로고
    • Differential effects on ARF stability by normal versus oncogenic levels of c-Myc expression
    • Chen D, Kon N, Zhong J, Zhang P, Yu L, Gu W. 2013a. Differential effects on ARF stability by normal versus oncogenic levels of c-Myc expression. Mol Cell 51: 46–56.
    • (2013) Mol Cell , vol.51 , pp. 46-56
    • Chen, D.1    Kon, N.2    Zhong, J.3    Zhang, P.4    Yu, L.5    Gu, W.6
  • 19
    • 84877907026 scopus 로고    scopus 로고
    • Lysine acetyltransferase GCN5 potentiates the growth of non-small cell lung cancer via promotion of E2F1, cyclin D1, and cyclin E1 expression
    • Chen L, Wei T, Si X, Wang Q, Li Y, Leng Y, Deng A, Chen J, Wang G, Zhu S, et al. 2013b. Lysine acetyltransferase GCN5 potentiates the growth of non-small cell lung cancer via promotion of E2F1, cyclin D1, and cyclin E1 expression. J Biol Chem 288: 14510–14521.
    • (2013) J Biol Chem , vol.288 , pp. 14510-14521
    • Chen, L.1    Wei, T.2    Si, X.3    Wang, Q.4    Li, Y.5    Leng, Y.6    Deng, A.7    Chen, J.8    Wang, G.9    Zhu, S.10
  • 20
    • 0032963671 scopus 로고    scopus 로고
    • Kalpana GV. 1999. c-MYC interactswith INI1/hSNF5 and requires the SWI/SNF complex for transactivation function
    • Cheng SW, Davies KP, Yung E, Beltran RJ, Yu J, Kalpana GV. 1999. c-MYC interactswith INI1/hSNF5 and requires the SWI/SNF complex for transactivation function. Nat Genet 22: 102–105.
    • Nat Genet , vol.22 , pp. 102-105
    • Cheng, S.W.1    Davies, K.P.2    Yung, E.3    Beltran, R.J.4    Yu, J.5
  • 22
    • 77953934816 scopus 로고    scopus 로고
    • Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells
    • Choi SH, Wright JB, Gerber SA, Cole MD. 2010. Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells. Genes Dev 24: 1236–1241.
    • (2010) Genes Dev , vol.24 , pp. 1236-1241
    • Choi, S.H.1    Wright, J.B.2    Gerber, S.A.3    Cole, M.D.4
  • 24
    • 33845399682 scopus 로고    scopus 로고
    • The Drosophila histone acetyltransferase Gcn5 and transriptional adaptor Ada2a are involved in nucleosomal histone H4 acetylation
    • Ciurciu A, Komonyi O, Pankotai T, Boros IM. 2006. The Drosophila histone acetyltransferase Gcn5 and transriptional adaptor Ada2a are involved in nucleosomal histone H4 acetylation. Mol Cell Biol 26: 9413–9423.
    • (2006) Mol Cell Biol , vol.26 , pp. 9413-9423
    • Ciurciu, A.1    Komonyi, O.2    Pankotai, T.3    Boros, I.M.4
  • 25
    • 0033551377 scopus 로고    scopus 로고
    • Myc-mediated transformation: The repression connection
    • Claassen GF, Hann SR. 1999. Myc-mediated transformation: The repression connection. Oncogene 18: 2925–2933.
    • (1999) Oncogene , vol.18 , pp. 2925-2933
    • Claassen, G.F.1    Hann, S.R.2
  • 26
    • 0034662959 scopus 로고    scopus 로고
    • A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor b-induced cell-cycle arrest
    • Claassen GF, Hann SR. 2000. A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor b-induced cell-cycle arrest. Proc Natl Acad Sci 97: 9498–9503.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 9498-9503
    • Claassen, G.F.1    Hann, S.R.2
  • 27
    • 84891770537 scopus 로고    scopus 로고
    • MYC association with cancer risk and a new model of MYC-mediated repression
    • Cole MD. 2014.MYC association with cancer risk and a new model of MYC-mediated repression. Cold Spring Harb Perspect Med doi: 10.1101/cshperspect.a014316.
    • (2014) Cold Spring Harb Perspect Med
    • Cole, M.D.1
  • 28
    • 52449101436 scopus 로고    scopus 로고
    • Transcription-independent functions of MYC: Regulation of translation and DNA replication
    • Cole MD, Cowling VH. 2008. Transcription-independent functions of MYC: Regulation of translation and DNA replication. Nat Rev Mol Cell Biol 9: 810–815.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 810-815
    • Cole, M.D.1    Cowling, V.H.2
  • 29
    • 77955330151 scopus 로고    scopus 로고
    • Mycnick: A cytoplasmic cleavage product of Myc that promotes a-tubulin acetylation and cell differentiation
    • Conacci-Sorrell M, Ngouenet C, Eisenman RN. 2010. Mycnick: A cytoplasmic cleavage product of Myc that promotes a-tubulin acetylation and cell differentiation. Cell 142: 480–493.
    • (2010) Cell , vol.142 , pp. 480-493
    • Conacci-Sorrell, M.1    Ngouenet, C.2    Eisenman, R.N.3
  • 33
    • 57149096666 scopus 로고    scopus 로고
    • N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor
    • Cotterman R, Jin VX, Krig SR, Lemen JM, Wey A, Farnham PJ, Knoepfler PS. 2008. N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. Cancer Res 68: 9654–9662.
    • (2008) Cancer Res , vol.68 , pp. 9654-9662
    • Cotterman, R.1    Jin, V.X.2    Krig, S.R.3    Lemen, J.M.4    Wey, A.5    Farnham, P.J.6    Knoepfler, P.S.7
  • 34
    • 33748145149 scopus 로고    scopus 로고
    • Mechanism of transcriptional activation by the Myc oncoproteins
    • Cowling VH, Cole MD. 2006.Mechanism of transcriptional activation by the Myc oncoproteins. Semin Cancer Biol 16: 242–252.
    • (2006) Semin Cancer Biol , vol.16 , pp. 242-252
    • Cowling, V.H.1    Cole, M.D.2
  • 35
    • 39749144542 scopus 로고    scopus 로고
    • An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II
    • Cowling VH, Cole MD. 2008. An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II. Oncogene 27: 1327–1332.
    • (2008) Oncogene , vol.27 , pp. 1327-1332
    • Cowling, V.H.1    Cole, M.D.2
  • 36
    • 37249024568 scopus 로고    scopus 로고
    • Feedback regulation of c-Myc by ribosomal protein L11
    • Dai MS, Sears R, Lu H. 2007. Feedback regulation of c-Myc by ribosomal protein L11. Cell Cycle 6: 2735–2741.
    • (2007) Cell Cycle , vol.6 , pp. 2735-2741
    • Dai, M.S.1    Sears, R.2    Lu, H.3
  • 37
    • 84859171807 scopus 로고    scopus 로고
    • MYCon the path to cancer
    • Dang CV. 2012.MYCon the path to cancer. Cell 149: 22–35.
    • (2012) Cell , vol.149 , pp. 22-35
    • Dang, C.V.1
  • 39
    • 0027315650 scopus 로고
    • A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice
    • Davis AC, Wims M, Spotts GD, Hann SR, Bradley A. 1993. A null c-myc mutation causes lethality before 10.5 days of gestation in homozygotes and reduced fertility in heterozygous female mice. Genes Dev 7: 671–682.
    • (1993) Genes Dev , vol.7 , pp. 671-682
    • Davis, A.C.1    Wims, M.2    Spotts, G.D.3    Hann, S.R.4    Bradley, A.5
  • 40
    • 33846326493 scopus 로고    scopus 로고
    • Cooperation betweenMyc and YY1 provides novel silencing transcriptional targets of a3b1-integrin in tumour cells
    • de Nigris F, Botti C, Rossiello R, Crimi E, Sica V, Napoli C. 2007. Cooperation betweenMyc and YY1 provides novel silencing transcriptional targets of a3b1-integrin in tumour cells. Oncogene 26: 382–394.
    • (2007) Oncogene , vol.26 , pp. 382-394
    • De Nigris, F.1    Botti, C.2    Rossiello, R.3    Crimi, E.4    Sica, V.5    Napoli, C.6
  • 41
    • 0035930571 scopus 로고    scopus 로고
    • Farnham PJ. 2001. c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism
    • Eberhardy SR, Farnham PJ. 2001. c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism. J Biol Chem 276: 48562–48571.
    • J Biol Chem , vol.276 , pp. 48562-48571
    • Eberhardy, S.R.1
  • 42
    • 0037131186 scopus 로고    scopus 로고
    • Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter
    • Eberhardy SR, Farnham PJ. 2002. Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter. J Biol Chem 277: 40156–40162.
    • (2002) J Biol Chem , vol.277 , pp. 40156-40162
    • Eberhardy, S.R.1    Farnham, P.J.2
  • 43
    • 1942437456 scopus 로고    scopus 로고
    • Bim is a suppressor ofMyc-induced mouse B cell leukemia
    • Egle A, Harris AW, Bouillet P, Cory S. 2004. Bim is a suppressor ofMyc-induced mouse B cell leukemia. Proc Natl Acad Sci 101: 6164–6169.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 6164-6169
    • Egle, A.1    Harris, A.W.2    Bouillet, P.3    Cory, S.4
  • 44
    • 0034953712 scopus 로고    scopus 로고
    • Apoptosis triggered byMyc-induced suppression of Bcl-XL or Bcl-2 is bypassed during lymphomagenesis
    • Eischen CM, Woo D, Roussel MF, Cleveland JL. 2001. Apoptosis triggered byMyc-induced suppression of Bcl-XL or Bcl-2 is bypassed during lymphomagenesis. Mol Cell Biol 21: 5063–5070.
    • (2001) Mol Cell Biol , vol.21 , pp. 5063-5070
    • Eischen, C.M.1    Woo, D.2    Roussel, M.F.3    Cleveland, J.L.4
  • 45
    • 0033678508 scopus 로고    scopus 로고
    • DNA methylation and histone deacetylation in the control of gene expression: Basic biochemistry to human development and disease
    • El-Osta A, Wolffe AP. 2000. DNA methylation and histone deacetylation in the control of gene expression: Basic biochemistry to human development and disease. Gene Expr 9: 63–75.
    • (2000) Gene Expr , vol.9 , pp. 63-75
    • El-Osta, A.1    Wolffe, A.P.2
  • 48
    • 46149110511 scopus 로고    scopus 로고
    • An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity
    • Fazzio TG, Huff JT, Panning B. 2008. An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell 134: 162–174.
    • (2008) Cell , vol.134 , pp. 162-174
    • Fazzio, T.G.1    Huff, J.T.2    Panning, B.3
  • 50
    • 0035881472 scopus 로고    scopus 로고
    • Binding of c-Myc to chromatin mediates mitogeninduced acetylation of histone H4 and gene activation
    • Frank SR, Schroeder M, Fernandez P, Taubert S, Amati B. 2001. Binding of c-Myc to chromatin mediates mitogeninduced acetylation of histone H4 and gene activation. Genes Dev 15: 2069–2082.
    • (2001) Genes Dev , vol.15 , pp. 2069-2082
    • Frank, S.R.1    Schroeder, M.2    Fernandez, P.3    Taubert, S.4    Amati, B.5
  • 52
    • 77956910209 scopus 로고    scopus 로고
    • Essential role of p400/mDomino chromatin-remodeling ATPase in bone marrow hematopoiesis and cell-cycle progression
    • Fujii T, Ueda T, Nagata S, Fukunaga R. 2010. Essential role of p400/mDomino chromatin-remodeling ATPase in bone marrow hematopoiesis and cell-cycle progression. J Biol Chem 285: 30214–30223.
    • (2010) J Biol Chem , vol.285 , pp. 30214-30223
    • Fujii, T.1    Ueda, T.2    Nagata, S.3    Fukunaga, R.4
  • 53
    • 84887147170 scopus 로고    scopus 로고
    • MYC activation is a hallmark of cancer initiation and maintenance
    • Gabay M, Li Y, Felsher DW. 2014. MYC activation is a hallmark of cancer initiation and maintenance. Cold Spring Harb Perspect Med doi: 10.1101/cshperspect.a014241.
    • (2014) Cold Spring Harb Perspect Med
    • Gabay, M.1    Li, Y.2    Felsher, D.W.3
  • 54
    • 0035836706 scopus 로고    scopus 로고
    • Hay N,Najmabadi F, Tyner AL
    • Gartel AL, Ye X, Goufman E, Shianov P, Hay N,Najmabadi F, Tyner AL. 2001. Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci 98: 4510–4515.
    • (2001) Proc Natl Acad Sci , vol.98 , pp. 4510-4515
    • Gartel, A.L.1    Ye, X.2    Goufman, E.3    Shianov, P.4
  • 55
    • 84861869979 scopus 로고    scopus 로고
    • Ubiquitin and proteasomes in transcription
    • Geng F, Wenzel S, Tansey WP. 2012. Ubiquitin and proteasomes in transcription. Annu Rev Biochem 81: 177–201.
    • (2012) Annu Rev Biochem , vol.81 , pp. 177-201
    • Geng, F.1    Wenzel, S.2    Tansey, W.P.3
  • 56
    • 84890591387 scopus 로고    scopus 로고
    • MYCNmediated transcriptional repression in neuroblastoma:The other side of the coin
    • Gherardi S, Valli E, Erriquez D, Perini G. 2013. MYCNmediated transcriptional repression in neuroblastoma:The other side of the coin. Front Oncol 3: 42.
    • (2013) Front Oncol , vol.3 , pp. 42
    • Gherardi, S.1    Valli, E.2    Erriquez, D.3    Perini, G.4
  • 57
    • 84873035945 scopus 로고    scopus 로고
    • The MYC-associated protein CDCA7 is phosphorylated by AKT to regulate MYC-dependent apoptosis and transformation
    • Gill RM, Gabor TV, Couzens AL, Scheid MP. 2013. The MYC-associated protein CDCA7 is phosphorylated by AKT to regulate MYC-dependent apoptosis and transformation. Mol Cell Biol 33: 498–513.
    • (2013) Mol Cell Biol , vol.33 , pp. 498-513
    • Gill, R.M.1    Gabor, T.V.2    Couzens, A.L.3    Scheid, M.P.4
  • 58
    • 33751279248 scopus 로고    scopus 로고
    • DNA damage, p14ARF, nucleophosmin (NPM/B23), and cancer
    • Gjerset RA. 2006. DNA damage, p14ARF, nucleophosmin (NPM/B23), and cancer. J Mol Histol 37: 239–251.
    • (2006) J Mol Histol , vol.37 , pp. 239-251
    • Gjerset, R.A.1
  • 59
    • 34547580590 scopus 로고    scopus 로고
    • HIF and cMyc: Aibling rivals for control of cancer cell metabolism and proliferation
    • Gordan JD, Thompson CB, Simon MC. 2007. HIF and cMyc: Aibling rivals for control of cancer cell metabolism and proliferation. Cancer Cell 12: 108–113.
    • (2007) Cancer Cell , vol.12 , pp. 108-113
    • Gordan, J.D.1    Thompson, C.B.2    Simon, M.C.3
  • 63
    • 25444479078 scopus 로고    scopus 로고
    • The ARF tumor suppressor: Keeping Myc on a leash
    • Gregory MA, Qi Y, Hann SR. 2005. The ARF tumor suppressor: Keeping Myc on a leash. Cell Cycle 4: 249–252.
    • (2005) Cell Cycle , vol.4 , pp. 249-252
    • Gregory, M.A.1    Qi, Y.2    Hann, S.R.3
  • 66
    • 0028307489 scopus 로고
    • Binding and suppression of the Myc transcriptional activation domain by p107
    • Gu W, Bhatia K, Magrath IT, Dang CV, Dalla-Favera R. 1994. Binding and suppression of the Myc transcriptional activation domain by p107. Science 264: 251–254.
    • (1994) Science , vol.264 , pp. 251-254
    • Gu, W.1    Bhatia, K.2    Magrath, I.T.3    Dang, C.V.4    Dalla-Favera, R.5
  • 68
    • 33748138585 scopus 로고    scopus 로고
    • Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function
    • Hann SR. 2006. Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function. Semin Cancer Biol 16: 288–302.
    • (2006) Semin Cancer Biol , vol.16 , pp. 288-302
    • Hann, S.R.1
  • 69
    • 0021688655 scopus 로고
    • Proteins encoded by the human c-myc oncogene: Differential expression in neoplastic cells
    • Hann SR, Eisenman RN. 1984. Proteins encoded by the human c-myc oncogene: Differential expression in neoplastic cells. Mol Cell Biol 4: 2486–2497.
    • (1984) Mol Cell Biol , vol.4 , pp. 2486-2497
    • Hann, S.R.1    Eisenman, R.N.2
  • 70
    • 0020616953 scopus 로고
    • Proteins encoded by v-myc and c-myc oncogenes: Identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines
    • Hann SR, Abrams HD, Rohrschneider LR, Eisenman RN.1983. Proteins encoded by v-myc and c-myc oncogenes: Identification and localization in acute leukemia virus transformants and bursal lymphoma cell lines. Cell 34: 789–798.
    • (1983) Cell , vol.34 , pp. 789-798
    • Hann, S.R.1    Abrams, H.D.2    Rohrschneider, L.R.3    Eisenman, R.N.4
  • 72
    • 79952828836 scopus 로고    scopus 로고
    • Transcriptional repression: The dark side of myc
    • Herkert B, Eilers M. 2010. Transcriptional repression: The dark side of myc. Genes Cancer 1: 580–586.
    • (2010) Genes Cancer , vol.1 , pp. 580-586
    • Herkert, B.1    Eilers, M.2
  • 75
    • 73449113904 scopus 로고    scopus 로고
    • Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
    • Hervouet E, Vallette FM, Cartron PF. 2009. Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation. Epigenetics 4: 487–499.
    • (2009) Epigenetics , vol.4 , pp. 487-499
    • Hervouet, E.1    Vallette, F.M.2    Cartron, P.F.3
  • 76
    • 0034718781 scopus 로고    scopus 로고
    • Differential activity of conditional MYC and its variant MYC-S in human mortal fibroblasts
    • Hirst SK, Grandori C. 2000. Differential activity of conditional MYC and its variant MYC-S in human mortal fibroblasts. Oncogene 19: 5189–5197.
    • (2000) Oncogene , vol.19 , pp. 5189-5197
    • Hirst, S.K.1    Grandori, C.2
  • 77
    • 33749572938 scopus 로고    scopus 로고
    • Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells
    • Hrzenjak A, Moinfar F, Kremser ML, Strohmeier B, Staber PB, Zatloukal K, Denk H. 2006. Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells. Mol Cancer Ther 5: 2203–2210.
    • (2006) Mol Cancer Ther , vol.5 , pp. 2203-2210
    • Hrzenjak, A.1    Moinfar, F.2    Kremser, M.L.3    Strohmeier, B.4    Staber, P.B.5    Zatloukal, K.6    Denk, H.7
  • 78
    • 15444362640 scopus 로고    scopus 로고
    • Trichostatin A induces transforming growth factor b type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/ p300 to a Sp1.NF-Y complex
    • Huang W, Zhao S, Ammanamanchi S, Brattain M, Venkatasubbarao K, Freeman JW. 2005. Trichostatin A induces transforming growth factor b type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/ p300 to a Sp1.NF-Y complex. J Biol Chem 280: 10047-10054.
    • (2005) J Biol Chem , vol.280 , pp. 10047-10054
    • Huang, W.1    Zhao, S.2    Ammanamanchi, S.3    Brattain, M.4    Venkatasubbarao, K.5    Freeman, J.W.6
  • 79
    • 77958507615 scopus 로고    scopus 로고
    • Cdk2: A key regulator of teh senescence control function of Myc
    • Hydbring P, Larsson LG. 2010. Cdk2: A key regulator of teh senescence control function of Myc. Aging (Albany NY) 2: 244–250.
    • (2010) Aging (Albany NY) , vol.2 , pp. 244-250
    • Hydbring, P.1    Larsson, L.G.2
  • 80
    • 78751532910 scopus 로고    scopus 로고
    • A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF
    • Iraci N, Diolaiti D, Papa A, Porro A, Valli E, Gherardi S, Herold S, Eilers M, Bernardoni R, Della Valle G, et al. 2011. A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF. Cancer Res 71: 404–412.
    • (2011) Cancer Res , vol.71 , pp. 404-412
    • Iraci, N.1    Diolaiti, D.2    Papa, A.3    Porro, A.4    Valli, E.5    Gherardi, S.6    Herold, S.7    Eilers, M.8    Bernardoni, R.9    Della Valle, G.10
  • 81
    • 0033539555 scopus 로고    scopus 로고
    • Eisenman RN. 1999. c-Myc enhances protein synthesis and cell size during B lymphocyte development
    • Iritani BM, Eisenman RN. 1999. c-Myc enhances protein synthesis and cell size during B lymphocyte development. Proc Natl Acad Sci 96: 13180–13185.
    • Proc Natl Acad Sci , vol.96 , pp. 13180-13185
    • Iritani, B.M.1
  • 82
    • 84882676636 scopus 로고    scopus 로고
    • AP4 directly downregulates p16 and p21 to suppress senescence and mediate ransformation
    • Jackstadt R, Jung P, Hermeking H. 2013. AP4 directly downregulates p16 and p21 to suppress senescence and mediate ransformation. Cell Death Dis 4: 775.
    • (2013) Cell Death Dis , vol.4 , pp. 775
    • Jackstadt, R.1    Jung, P.2    Hermeking, H.3
  • 84
    • 35148858784 scopus 로고    scopus 로고
    • C-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter
    • Jiang G, Espeseth A, Hazuda DJ, Margolis DM. 2007. c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter. J Virol 81: 10914–10923.
    • (2007) J Virol , vol.81 , pp. 10914-10923
    • Jiang, G.1    Espeseth, A.2    Hazuda, D.J.3    Margolis, D.M.4
  • 85
    • 65949100126 scopus 로고    scopus 로고
    • The c-MYC-AP4-p21 cascade
    • Jung P, Hermeking H. 2009. The c-MYC-AP4-p21 cascade. Cell Cycle 8: 982–989.
    • (2009) Cell Cycle , vol.8 , pp. 982-989
    • Jung, P.1    Hermeking, H.2
  • 88
    • 84872523847 scopus 로고    scopus 로고
    • MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 methyltransferase
    • Kaur M, Cole MD. 2013. MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 methyltransferase. Cancer Res 73: 695–705.
    • (2013) Cancer Res , vol.73 , pp. 695-705
    • Kaur, M.1    Cole, M.D.2
  • 92
    • 46349099384 scopus 로고    scopus 로고
    • Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo
    • Kim J, Lee JH, Iyer VR. 2008. Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo. PLoS ONE 3: 1798.
    • (2008) Plos ONE , vol.3 , pp. 1798
    • Kim, J.1    Lee, J.H.2    Iyer, V.R.3
  • 94
    • 61449143491 scopus 로고    scopus 로고
    • The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
    • Knuesel MT, Meyer KD, Bernecky C, Taatjes DJ. 2009. The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function. Genes Dev 23: 439–451.
    • (2009) Genes Dev , vol.23 , pp. 439-451
    • Knuesel, M.T.1    Meyer, K.D.2    Bernecky, C.3    Taatjes, D.J.4
  • 96
    • 45549095542 scopus 로고    scopus 로고
    • Myc-mediated transcriptional repression by recruitment of histone deacetylase
    • Kurland JF, Tansey WP. 2008.Myc-mediated transcriptional repression by recruitment of histone deacetylase. Cancer Res 68: 3624–3629.
    • (2008) Cancer Res , vol.68 , pp. 3624-3629
    • Kurland, J.F.1    Tansey, W.P.2
  • 97
    • 2942715351 scopus 로고    scopus 로고
    • VP16 and ubiquitin; binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes
    • Kurosu T, Peterlin BM. 2004. VP16 and ubiquitin; binding of P-TEFb via its activation domain and ubiquitin facilitates elongation of transcription of target genes. Curr Biol 14: 1112–1116.
    • (2004) Curr Biol , vol.14 , pp. 1112-1116
    • Kurosu, T.1    Peterlin, B.M.2
  • 99
    • 33646422463 scopus 로고    scopus 로고
    • Reversible kinetic analysis of Myc targets in vivo provides novel insights intoMyc-mediated tumorigenesis
    • Lawlor ER, Soucek L, Brown-Swigart L, Shchors K, Bialucha CU, Evan GI. 2006. Reversible kinetic analysis of Myc targets in vivo provides novel insights intoMyc-mediated tumorigenesis. Cancer Res 66: 4591–4601.
    • (2006) Cancer Res , vol.66 , pp. 4591-4601
    • Lawlor, E.R.1    Soucek, L.2    Brown-Swigart, L.3    Shchors, K.4    Bialucha, C.U.5    Evan, G.I.6
  • 100
    • 0030995824 scopus 로고    scopus 로고
    • Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
    • Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR. 1997.Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature 387: 422–426.
    • (1997) Nature , vol.387 , pp. 422-426
    • Leone, G.1    Degregori, J.2    Sears, R.3    Jakoi, L.4    Nevins, J.R.5
  • 102
    • 84887191036 scopus 로고    scopus 로고
    • CellularMYCro economics: BalancingMYC function with MYC expression
    • Levens D. 2013.CellularMYCro economics: BalancingMYC function with MYC expression. Cold Spring Harb Perspect Med 3: 014233.
    • (2013) Cold Spring Harb Perspect Med , vol.3 , pp. 014233
    • Levens, D.1
  • 103
    • 77956611413 scopus 로고    scopus 로고
    • The role of Sp1 and Sp3 in normal and cancer cell biology
    • Li L, Davie JR. 2010. The role of Sp1 and Sp3 in normal and cancer cell biology. Ann Anat 192: 275–283.
    • (2010) Ann Anat , vol.192 , pp. 275-283
    • Li, L.1    Davie, J.R.2
  • 104
    • 69749086004 scopus 로고    scopus 로고
    • The Myc-nucleophosmin-ARF network: A complex web unveiled
    • Li Z, Hann SR. 2009. The Myc-nucleophosmin-ARF network: A complex web unveiled. Cell Cycle 8: 2703–2707.
    • (2009) Cell Cycle , vol.8 , pp. 2703-2707
    • Li, Z.1    Hann, S.R.2
  • 105
    • 84876104926 scopus 로고    scopus 로고
    • Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription
    • Li Z, Hann SR. 2013. Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription. Oncogene 32: 1988–1994.
    • (2013) Oncogene , vol.32 , pp. 1988-1994
    • Li, Z.1    Hann, S.R.2
  • 106
    • 0028169192 scopus 로고
    • C-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II
    • Li LH, Nerlov C, Prendergast G, MacGregor D, Ziff EB. 1994. c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. EMBO J 13: 4070–4079.
    • (1994) EMBO J , vol.13 , pp. 4070-4079
    • Li, L.H.1    Nerlov, C.2    Prendergast, G.3    Macgregor, D.4    Ziff, E.B.5
  • 107
    • 57749116048 scopus 로고    scopus 로고
    • Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation
    • Li Z, Boone D, Hann SR. 2008. Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation. Proc Natl Acad Sci 105: 18794–18799.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 18794-18799
    • Li, Z.1    Boone, D.2    Hann, S.R.3
  • 110
    • 0038820074 scopus 로고    scopus 로고
    • C-Myc transformation domain recruits the human STAGAcomplex and requires TRRAPand GCN5 acetylase activity for transcription activation
    • Liu X, Tesfai J, Evrard YA, Dent SY, Martinez E. 2003. c-Myc transformation domain recruits the human STAGAcomplex and requires TRRAPand GCN5 acetylase activity for transcription activation. Mol Cell Biol 278: 20405–20412.
    • (2003) Mol Cell Biol , vol.278 , pp. 20405-20412
    • Liu, X.1    Tesfai, J.2    Evrard, Y.A.3    Dent, S.Y.4    Martinez, E.5
  • 111
    • 36749069011 scopus 로고    scopus 로고
    • Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis
    • Liu T, Tee AE, Porro A, Smith SA, Dwarte T, Liu PY, Iraci N, Sekyere E, Haber M, Norris MD, et al. 2007. Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis. Proc Natl Acad Sci 104: 18682–18687.
    • (2007) Proc Natl Acad Sci , vol.104 , pp. 18682-18687
    • Liu, T.1    Tee, A.E.2    Porro, A.3    Smith, S.A.4    Dwarte, T.5    Liu, P.Y.6    Iraci, N.7    Sekyere, E.8    Haber, M.9    Norris, M.D.10
  • 112
    • 37549044715 scopus 로고    scopus 로고
    • STAGA recruitsMediator to the MYC oncoprotein to stimulate transcription and cell proliferation
    • Liu X, Vorontchikhina M, Wang YL, Faiola F, Martinez E. 2008. STAGA recruitsMediator to the MYC oncoprotein to stimulate transcription and cell proliferation. Mol Cell Biol 28: 108–121.
    • (2008) Mol Cell Biol , vol.28 , pp. 108-121
    • Liu, X.1    Vorontchikhina, M.2    Wang, Y.L.3    Faiola, F.4    Martinez, E.5
  • 114
    • 77954234114 scopus 로고    scopus 로고
    • Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool
    • Loizou JI, Oser G, Shukla V, Sawan C, Murr R, Wang ZQ, Trumpp A, Herceg Z. 2009. Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool. Mol Cell Biol 183: 6422–6431.
    • (2009) Mol Cell Biol , vol.183 , pp. 6422-6431
    • Loizou, J.I.1    Oser, G.2    Shukla, V.3    Sawan, C.4    Murr, R.5    Wang, Z.Q.6    Trumpp, A.7    Herceg, Z.8
  • 115
    • 84856338151 scopus 로고    scopus 로고
    • Regulation of gene transcription by the oncoprotein MYC
    • Luscher B, Vervoorts J. 2012. Regulation of gene transcription by the oncoprotein MYC. Mol Cell Biol 494: 145–160.
    • (2012) Mol Cell Biol , vol.494 , pp. 145-160
    • Luscher, B.1    Vervoorts, J.2
  • 116
    • 0028023421 scopus 로고
    • Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis
    • Lutterbach B, Hann SR. 1994. Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis. Mol Cell Biol 14: 5510–5522.
    • (1994) Mol Cell Biol , vol.14 , pp. 5510-5522
    • Lutterbach, B.1    Hann, S.R.2
  • 118
    • 56649107917 scopus 로고    scopus 로고
    • Analysis of Myc-induced histone modifications on target chromatin
    • Martinato F, Cesaroni M, Amati B, Guccione E. 2008. Analysis of Myc-induced histone modifications on target chromatin. PLoS ONE 3: 3650.
    • (2008) Plos ONE , vol.3 , pp. 3650
    • Martinato, F.1    Cesaroni, M.2    Amati, B.3    Guccione, E.4
  • 120
    • 38949135139 scopus 로고    scopus 로고
    • Induction of a novel histone deacetylase 1/c-Myc/ Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis
    • Matsuoka Y, Fukamachi K, Uehara N, Tsuda H, Tsubura A. 2008. Induction of a novel histone deacetylase 1/c-Myc/ Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis. Cancer Sci 99: 309–315.
    • (2008) Cancer Sci , vol.99 , pp. 309-315
    • Matsuoka, Y.1    Fukamachi, K.2    Uehara, N.3    Tsuda, H.4    Tsubura, A.5
  • 123
    • 0033970431 scopus 로고    scopus 로고
    • The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc
    • McMahon SB, Wood MA, Cole MD. 2000. The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc. Mol Cell Biol 20: 556–562.
    • (2000) Mol Cell Biol , vol.20 , pp. 556-562
    • McMahon, S.B.1    Wood, M.A.2    Cole, M.D.3
  • 124
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ. 2008. Reflecting on 25 years with MYC. Nat Rev Cancer 8: 976–990.
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 125
    • 26444480631 scopus 로고    scopus 로고
    • Mechanisms of tumor suppression by the SCFFbw7
    • Minella AC, Clurman BE. 2005.Mechanisms of tumor suppression by the SCFFbw7. Cell Cycle 4: 1356–1359.
    • (2005) Cell Cycle , vol.4 , pp. 1356-1359
    • Minella, A.C.1    Clurman, B.E.2
  • 126
    • 0037335034 scopus 로고    scopus 로고
    • How the ubiquitin-proteasome system controls transcription
    • Muratani M, Tansey WP. 2003. How the ubiquitin-proteasome system controls transcription. Nat Rev Mol Cell Biol 4: 192–201.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 192-201
    • Muratani, M.1    Tansey, W.P.2
  • 127
    • 34547902154 scopus 로고    scopus 로고
    • Orchestration of chromatin-based processes: Mind the TRRAP
    • Murr R, Vaissiere T, Sawan C, Shukla V, Herceg Z. 2007. Orchestration of chromatin-based processes: Mind the TRRAP. Oncogene 26: 5358–5372.
    • (2007) Oncogene , vol.26 , pp. 5358-5372
    • Murr, R.1    Vaissiere, T.2    Sawan, C.3    Shukla, V.4    Herceg, Z.5
  • 128
    • 84867010006 scopus 로고    scopus 로고
    • Casellas R, et al. 2012. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
    • Nie Z, Hu G, Wei G, Cui K, Yamane A, Resch W, Wang R, Green DR, Tessarollo L, Casellas R, et al. 2012. c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell 151: 68–79.
    • Cell , vol.151 , pp. 68-79
    • Nie, Z.1    Hu, G.2    Wei, G.3    Cui, K.4    Yamane, A.5    Resch, W.6    Wang, R.7    Green, D.R.8    Tessarollo, L.9
  • 131
    • 77956313888 scopus 로고    scopus 로고
    • The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate c-myc target genes in mammalian tumor cells
    • O’Donovan KJ, Diedler J, Couture GC, Fak JJ, Darnell RB. 2010. The onconeural antigen cdr2 is a novel APC/C target that acts in mitosis to regulate c-myc target genes in mammalian tumor cells. PLoS ONE 5: 10045.
    • (2010) Plos ONE , vol.5 , pp. 10045
    • O’Donovan, K.J.1    Diedler, J.2    Couture, G.C.3    Fak, J.J.4    Darnell, R.B.5
  • 133
    • 0037417130 scopus 로고    scopus 로고
    • Functional analysis of the N-terminal domain of the Myc oncoprotein
    • Oster SK, Mao DY, Kennedy J, Penn LZ. 2003. Functional analysis of the N-terminal domain of the Myc oncoprotein. Oncogene 22: 1998–2010.
    • (2003) Oncogene , vol.22 , pp. 1998-2010
    • Oster, S.K.1    Mao, D.Y.2    Kennedy, J.3    Penn, L.Z.4
  • 134
    • 0142123234 scopus 로고    scopus 로고
    • Sif S. 2003. mSin3A/histone deaetylase 2 and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad
    • Pal S, Yun R, Datta A, Lacomis L, Erdjument-Bromage H, Kumar J, Tempst P, Sif S. 2003. mSin3A/histone deaetylase 2 and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad. Mol Cell Biol 23: 7475–7487.
    • Mol Cell Biol , vol.23 , pp. 7475-7487
    • Pal, S.1    Yun, R.2    Datta, A.3    Lacomis, L.4    Erdjument-Bromage, H.5    Kumar, J.6    Tempst, P.7
  • 135
    • 0036173140 scopus 로고    scopus 로고
    • BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation
    • Park J, Wood MA, Cole MD. 2002. BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation. Mol Cell Biol 22: 1307–1316.
    • (2002) Mol Cell Biol , vol.22 , pp. 1307-1316
    • Park, J.1    Wood, M.A.2    Cole, M.D.3
  • 136
    • 33645649406 scopus 로고    scopus 로고
    • Targeting of Miz-1 is essential for Myc-mediated apoptosis
    • Patel JH, McMahon SB. 2006. Targeting of Miz-1 is essential for Myc-mediated apoptosis. J Biol Chem 281: 3283–3289.
    • (2006) J Biol Chem , vol.281 , pp. 3283-3289
    • Patel, J.H.1    McMahon, S.B.2
  • 137
    • 33846948993 scopus 로고    scopus 로고
    • BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis
    • Patel JH, McMahon SB. 2007. BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis. J Biol Chem 282: 5–13.
    • (2007) J Biol Chem , vol.282 , pp. 5-13
    • Patel, J.H.1    McMahon, S.B.2
  • 140
    • 22044446356 scopus 로고    scopus 로고
    • A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants
    • Pineda-Lucena A, Ho CS, Mao DY, Sheng Y, Laister RC, Muhandiram R, Lu Y, Seet BT, Katz S, Szyperski T, et al. 2005. A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants. J Mol Biol 351: 182–194.
    • (2005) J Mol Biol , vol.351 , pp. 182-194
    • Pineda-Lucena, A.1    Ho, C.S.2    Mao, D.Y.3    Sheng, Y.4    Laister, R.C.5    Muhandiram, R.6    Lu, Y.7    Seet, B.T.8    Katz, S.9    Szyperski, T.10
  • 142
    • 32244446201 scopus 로고    scopus 로고
    • Mnt transcriptional repressor is functionally regulated during cell cycle progression
    • Popov N, Wahlstrom T, Hurlin PJ, Henriksson M. 2005. Mnt transcriptional repressor is functionally regulated during cell cycle progression. Oncogene 24: 8326–8337.
    • (2005) Oncogene , vol.24 , pp. 8326-8337
    • Popov, N.1    Wahlstrom, T.2    Hurlin, P.J.3    Henriksson, M.4
  • 143
    • 77957564565 scopus 로고    scopus 로고
    • Ubiquitylation of the amino terminus of Myc by SCFb-TrCP antagonizes SCFFbw7-mediated turnover
    • Popov N, Schulein C, Jaenicke LA, Eilers M. 2010. Ubiquitylation of the amino terminus of Myc by SCFb-TrCP antagonizes SCFFbw7-mediated turnover. Nat Cell Biol 12: 973–981.
    • (2010) Nat Cell Biol , vol.12 , pp. 973-981
    • Popov, N.1    Schulein, C.2    Jaenicke, L.A.3    Eilers, M.4
  • 144
    • 6044254972 scopus 로고    scopus 로고
    • P19ARF directly and differentially controls the functions of c-Myc independently of p53
    • Qi Y, Gregory MA, Li Z, Brousal JP, West K, Hann SR. 2004. p19ARF directly and differentially controls the functions of c-Myc independently of p53. Nature 431: 712–717.
    • (2004) Nature , vol.431 , pp. 712-717
    • Qi, Y.1    Gregory, M.A.2    Li, Z.3    Brousal, J.P.4    West, K.5    Hann, S.R.6
  • 145
    • 78751646290 scopus 로고    scopus 로고
    • Identification and regulation of c-Myb target genes in MCF-7 cells
    • Quintana AM, Liu F, O’Rourke JP, Ness SA. 2011. Identification and regulation of c-Myb target genes in MCF-7 cells. BMC Cancer 11: 30.
    • (2011) BMC Cancer , vol.11 , pp. 30
    • Quintana, A.M.1    Liu, F.2    O’Rourke, J.P.3    Ness, S.A.4
  • 147
    • 79952197153 scopus 로고    scopus 로고
    • Histone variant H2A.Z can serve as a new target for breast cancer therapy
    • Rangasamy D. 2010. Histone variant H2A.Z can serve as a new target for breast cancer therapy. Curr Med Chem 17: 3155–3161.
    • (2010) Curr Med Chem , vol.17 , pp. 3155-3161
    • Rangasamy, D.1
  • 151
    • 0029741917 scopus 로고    scopus 로고
    • BIN1 is a novel MYC-interacting protein with features of a tumour suppressor
    • Sakamuro D, Elliott KJ, Wechsler-Reya R, Prendergast GC. 1996. BIN1 is a novel MYC-interacting protein with features of a tumour suppressor. Nat Genet 14: 69–77.
    • (1996) Nat Genet , vol.14 , pp. 69-77
    • Sakamuro, D.1    Elliott, K.J.2    Wechsler-Reya, R.3    Prendergast, G.C.4
  • 154
    • 0035824666 scopus 로고    scopus 로고
    • A novel transrepression pathway of c-Myc. Recruitment of a transcriptional corepressor complex to c-Myc by MM-1, a c-Myc-binding protein
    • Satou A, Taira T, Iguchi-Ariga SM, Ariga H. 2001. A novel transrepression pathway of c-Myc. Recruitment of a transcriptional corepressor complex to c-Myc by MM-1, a c-Myc-binding protein. J Biol Chem 276: 46562–46567.
    • (2001) J Biol Chem , vol.276 , pp. 46562-46567
    • Satou, A.1    Taira, T.2    Iguchi-Ariga, S.M.3    Ariga, H.4
  • 155
    • 0030879961 scopus 로고    scopus 로고
    • Association ofMyc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc
    • Schneider A, Peukert K, Eilers M, Hanel F. 1997. Association ofMyc with the zinc-finger protein Miz-1 defines a novel pathway for gene regulation by Myc. Curr Top Microbiol Immunol 224: 137–146.
    • (1997) Curr Top Microbiol Immunol , vol.224 , pp. 137-146
    • Schneider, A.1    Peukert, K.2    Eilers, M.3    Hanel, F.4
  • 157
    • 34547687916 scopus 로고    scopus 로고
    • The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: The Myc connection
    • Secombe J, Eisenman RN. 2007. The function and regulation of the JARID1 family of histone H3 lysine 4 demethylases: The Myc connection. Cell Cycle 6: 1324–1328.
    • (2007) Cell Cycle , vol.6 , pp. 1324-1328
    • Secombe, J.1    Eisenman, R.N.2
  • 158
    • 47049104369 scopus 로고    scopus 로고
    • Cdk5-mediated phosphorylation of c-Myc on Ser-62 is essential in transcriptional activation of cyclin B1 by cyclin G1
    • Seo HR, Kim J, Bae S, Soh JW, Lee YS. 2008. Cdk5-mediated phosphorylation of c-Myc on Ser-62 is essential in transcriptional activation of cyclin B1 by cyclin G1. J Biol Chem 283: 15601–15610.
    • (2008) J Biol Chem , vol.283 , pp. 15601-15610
    • Seo, H.R.1    Kim, J.2    Bae, S.3    Soh, J.W.4    Lee, Y.S.5
  • 159
    • 33747819484 scopus 로고    scopus 로고
    • Divorcing ARF and p53: An unsettled case
    • Sherr CJ. 2006. Divorcing ARF and p53: An unsettled case. Nat Rev Cancer 6: 663–673.
    • (2006) Nat Rev Cancer , vol.6 , pp. 663-673
    • Sherr, C.J.1
  • 160
    • 77956214711 scopus 로고    scopus 로고
    • Myc represses rimitive endoderm differentiation in pluripotent stem cells
    • Smith KN, Singh AM, Dalton S. 2010. Myc represses rimitive endoderm differentiation in pluripotent stem cells. Cell Stem Cell 7: 343–354.
    • (2010) Cell Stem Cell , vol.7 , pp. 343-354
    • Smith, K.N.1    Singh, A.M.2    Dalton, S.3
  • 161
    • 0031037987 scopus 로고    scopus 로고
    • Identification of downstream-initiated c-Myc proteins which are dominant negative inhibitors of transactivation by full-length c-Myc proteins
    • Spotts GD, Patel SV, Xiao Q, Hann SR. 1997. Identification of downstream-initiated c-Myc proteins which are dominant negative inhibitors of transactivation by full-length c-Myc proteins. Mol Cell Biol 17: 1459–1468.
    • (1997) Mol Cell Biol , vol.17 , pp. 1459-1468
    • Spotts, G.D.1    Patel, S.V.2    Xiao, Q.3    Hann, S.R.4
  • 163
    • 79956140606 scopus 로고    scopus 로고
    • To cross or not to cross the nucleosome, that is the elongation question
    • Subtil-Rodriguez A, Reyes JC. 2011. To cross or not to cross the nucleosome, that is the elongation question. RNABiol 8: 389–393.
    • (2011) Rnabiol , vol.8 , pp. 389-393
    • Subtil-Rodriguez, A.1    Reyes, J.C.2
  • 165
    • 79959450256 scopus 로고    scopus 로고
    • Proteolytic control of the oncoprotein transcription factor Myc
    • Thomas LR, Tansey WP. 2011. Proteolytic control of the oncoprotein transcription factor Myc. Nat Cell Biol 110: 77–106.
    • (2011) Nat Cell Biol , vol.110 , pp. 77-106
    • Thomas, L.R.1    Tansey, W.P.2
  • 166
    • 84934443208 scopus 로고    scopus 로고
    • An efficient way of studying protein protein interactions involving HIF-a, c-Myc, and Sp1
    • To KK, Huang LE. 2013. An efficient way of studying protein protein interactions involving HIF-a, c-Myc, and Sp1. Nat Cell Biol 1012: 77–84.
    • (2013) Nat Cell Biol , vol.1012 , pp. 77-84
    • To, K.K.1    Huang, L.E.2
  • 168
    • 70350233471 scopus 로고    scopus 로고
    • Acting locally and globally: Myc’s ever-expanding roles on chromatin
    • Varlakhanova NV, Knoepfler PS. 2009. Acting locally and globally: Myc’s ever-expanding roles on chromatin. Nat Cell Biol 69: 7487–7490.
    • (2009) Nat Cell Biol , vol.69 , pp. 7487-7490
    • Varlakhanova, N.V.1    Knoepfler, P.S.2
  • 170
    • 33845919326 scopus 로고    scopus 로고
    • The ins and outs of MYC regulation by posttranslational mechanisms
    • Vervoorts J, Luscher-Firzlaff J, Luscher B. 2006. The ins and outs of MYC regulation by posttranslational mechanisms. J Biol Chem 281: 34725–34729.
    • (2006) J Biol Chem , vol.281 , pp. 34725-34729
    • Vervoorts, J.1    Luscher-Firzlaff, J.2    Luscher, B.3
  • 173
    • 81155123696 scopus 로고    scopus 로고
    • MYC protein inhibits transcription of the microRNA cluster MC-let-7a-1_let-7d via noncanonical E-box
    • Wang Z, Lin S, Li JJ, Xu Z, Yao H, Zhu X, Xie D, Shen Z, Sze J, Li K, et al. 2011b. MYC protein inhibits transcription of the microRNA cluster MC-let-7a-1_let-7d via noncanonical E-box. J Biol Chem 286: 39703–39714.
    • (2011) J Biol Chem , vol.286 , pp. 39703-39714
    • Wang, Z.1    Lin, S.2    Li, J.J.3    Xu, Z.4    Yao, H.5    Zhu, X.6    Xie, D.7    Shen, Z.8    Sze, J.9    Li, K.10
  • 174
    • 72549085551 scopus 로고    scopus 로고
    • Genomic actions of estrogen receptor a: What are the targets and how are they regulated?
    • Welboren WJ, Sweep FC, Span PN, Stunnenberg HG. 2009. Genomic actions of estrogen receptor a: What are the targets and how are they regulated? Endocr Relat Cancer 16: 1073–1089.
    • (2009) Endocr Relat Cancer , vol.16 , pp. 1073-1089
    • Welboren, W.J.1    Sweep, F.C.2    Span, P.N.3    Stunnenberg, H.G.4
  • 175
    • 6944227551 scopus 로고    scopus 로고
    • A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size
    • Welcker M, Orian A, Grim JE, Eisenman RN, Clurman BE. 2004a. A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size. Curr Biol 14: 1852–1857.
    • (2004) Curr Biol , vol.14 , pp. 1852-1857
    • Welcker, M.1    Orian, A.2    Grim, J.E.3    Eisenman, R.N.4    Clurman, B.E.5
  • 176
    • 2942650133 scopus 로고    scopus 로고
    • The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylationdependent c-Myc protein degradation
    • Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE. 2004b. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylationdependent c-Myc protein degradation. Proc Natl Acad Sci 101: 9085–9090.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 9085-9090
    • Welcker, M.1    Orian, A.2    Jin, J.3    Grim, J.E.4    Harper, J.W.5    Eisenman, R.N.6    Clurman, B.E.7
  • 178
    • 82355184456 scopus 로고    scopus 로고
    • Histone chaperone FACT coordinates nucleosome Interaction through multiple synergistic binding events
    • Winkler DD, Muthurajan UM, Hieb AR, Luger K. 2011. Histone chaperone FACT coordinates nucleosome Interaction through multiple synergistic binding events. J Biol Chem 286: 41883–41892.
    • (2011) J Biol Chem , vol.286 , pp. 41883-41892
    • Winkler, D.D.1    Muthurajan, U.M.2    Hieb, A.R.3    Luger, K.4
  • 179
    • 0034660330 scopus 로고    scopus 로고
    • Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo
    • Wittschieben BO, Fellows J, Du W, Stillman DJ, Svejstrup JQ. 2000. Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo. EMBO J 19: 3060–3068.
    • (2000) EMBO J , vol.19 , pp. 3060-3068
    • Wittschieben, B.O.1    Fellows, J.2    Du, W.3    Stillman, D.J.4    Svejstrup, J.Q.5
  • 180
    • 0033859666 scopus 로고    scopus 로고
    • An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc
    • Wood MA, McMahon SB, Cole MD. 2000. An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-Myc. Mol Cell 5: 321–330.
    • (2000) Mol Cell , vol.5 , pp. 321-330
    • Wood, M.A.1    McMahon, S.B.2    Cole, M.D.3
  • 181
    • 0032535253 scopus 로고    scopus 로고
    • Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis
    • Xiao Q, Claassen G, Shi J, Adachi S, Sedivy J, Hann SR. 1998. Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis. Genes Dev 12: 3803–3808.
    • (1998) Genes Dev , vol.12 , pp. 3803-3808
    • Xiao, Q.1    Claassen, G.2    Shi, J.3    Adachi, S.4    Sedivy, J.5    Hann, S.R.6
  • 183
    • 58149378334 scopus 로고    scopus 로고
    • Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells
    • Yang J, Chai L, Fowles TC, Alipio Z, Xu D, Fink LM, Ward DC, Ma Y. 2008. Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells. Proc Natl Acad Sci 105: 19756–19761.
    • (2008) Proc Natl Acad Sci , vol.105 , pp. 19756-19761
    • Yang, J.1    Chai, L.2    Fowles, T.C.3    Alipio, Z.4    Xu, D.5    Fink, L.M.6    Ward, D.C.7    Ma, Y.8
  • 184
    • 84874641221 scopus 로고    scopus 로고
    • A subset of Drosophila Myc sites remain associated with mitotic chromosomes colocalized with insulator proteins
    • Yang J, Sung E, Donlin-Asp PG, Corces VG. 2013. A subset of Drosophila Myc sites remain associated with mitotic chromosomes colocalized with insulator proteins. Nat Commun 4: 1464.
    • (2013) Nat Commun , vol.4 , pp. 1464
    • Yang, J.1    Sung, E.2    Donlin-Asp, P.G.3    Corces, V.G.4
  • 185
    • 84867606040 scopus 로고    scopus 로고
    • Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-cell lymphomas
    • Zhang X, Zhao X, Fiskus W, Lin J, Lwin T, Rao R, Zhang Y, Chan JC, Fu K, Marquez VE, et al. 2012. Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-cell lymphomas. Cancer Cell 22: 506–523.
    • (2012) Cancer Cell , vol.22 , pp. 506-523
    • Zhang, X.1    Zhao, X.2    Fiskus, W.3    Lin, J.4    Lwin, T.5    Rao, R.6    Zhang, Y.7    Chan, J.C.8    Fu, K.9    Marquez, V.E.10
  • 186
    • 84872548776 scopus 로고    scopus 로고
    • Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity
    • Zhang Q, Spears E, Boone DN, Li Z, Gregory MA, Hann SR. 2013. Domain-specific c-Myc ubiquitylation controls c-Myc transcriptional and apoptotic activity. Proc Natl Acad Sci 110: 978–983.
    • (2013) Proc Natl Acad Sci , vol.110 , pp. 978-983
    • Zhang, Q.1    Spears, E.2    Boone, D.N.3    Li, Z.4    Gregory, M.A.5    Hann, S.R.6
  • 187
    • 44649201561 scopus 로고    scopus 로고
    • The HECTdomain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein
    • Zhao X, Heng JI, Guardavaccaro D, Jiang R, Pagano M, Guillemot F, Iavarone A, Lasorella A. 2008. The HECTdomain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein. Nat Cell Biol 10: 643–653.
    • (2008) Nat Cell Biol , vol.10 , pp. 643-653
    • Zhao, X.1    Heng, J.I.2    Guardavaccaro, D.3    Jiang, R.4    Pagano, M.5    Guillemot, F.6    Iavarone, A.7    Lasorella, A.8
  • 188
    • 84881224361 scopus 로고    scopus 로고
    • Ribosomal protein S14 negatively regulates c-Myc activity
    • Zhou X, Hao Q, Liao JM, Liao P, Lu H. 2013. Ribosomal protein S14 negatively regulates c-Myc activity. J Biol Chem 288: 21793–21801.
    • (2013) J Biol Chem , vol.288 , pp. 21793-21801
    • Zhou, X.1    Hao, Q.2    Liao, J.M.3    Liao, P.4    Lu, H.5
  • 190
    • 34547599505 scopus 로고    scopus 로고
    • PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation
    • Zippo A, De Robertis A, Serafini R, Oliviero S. 2007. PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation. Nat Cell Biol 9: 932–944.
    • (2007) Nat Cell Biol , vol.9 , pp. 932-944
    • Zippo, A.1    De Robertis, A.2    Serafini, R.3    Oliviero, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.