메뉴 건너뛰기




Volumn 8, Issue 7, 2009, Pages 982-989

The c-MYC-AP4-p21 cascade

Author keywords

AP4; c MYC; Cell cycle; Colorectal cancer; DNA damage; p21; p53; TFAP4; Wnt signaling

Indexed keywords

MYC PROTEIN; PROTEIN P21; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 65949100126     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.8.7.7949     Document Type: Review
Times cited : (84)

References (106)
  • 1
    • 33748159177 scopus 로고    scopus 로고
    • 25 years of the c-Myc oncogene
    • DOI 10.1016/j.semcancer.2006.08.003, PII S1044579X06000691, 25 Years of ther c-Myc Oncogene
    • Cole MD, Henriksson M. 25 years of the c-Myc oncogene. Semin Cancer Biol 2006; 16:241. (Pubitemid 44311042)
    • (2006) Seminars in Cancer Biology , vol.16 , Issue.4 , pp. 241
    • Cole, M.D.1    Henriksson, M.2
  • 2
  • 3
    • 56749184298 scopus 로고    scopus 로고
    • Reflecting on 25 years with MYC
    • Meyer N, Penn LZ. Reflecting on 25 years with MYC. Nat Rev Cancer 2008; 8:976-990
    • (2008) Nat Rev Cancer , vol.8 , pp. 976-990
    • Meyer, N.1    Penn, L.Z.2
  • 4
    • 0036781812 scopus 로고    scopus 로고
    • C-MYC: More than just a matter of life and death
    • DOI 10.1038/nrc904
    • Pelengaris S, Khan M, Evan G. c-MYC: more than just a matter of life and death. Nat Rev Cancer 2002; 2:764-776 (Pubitemid 37328911)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.10 , pp. 764-776
    • Pelengaris, S.1    Khan, M.2    Evan, G.3
  • 5
    • 56349158720 scopus 로고    scopus 로고
    • The curious case of the tumour virus: 50 Years of Burkitt's lymphoma
    • Thorley-Lawson DA, Allday MJ. The curious case of the tumour virus: 50 years of Burkitt's lymphoma. Nat Rev Microbiol 2008; 6:913-924
    • (2008) Nat Rev Microbiol , vol.6 , pp. 913-924
    • Thorley-Lawson, D.A.1    Allday, M.J.2
  • 6
    • 0033551374 scopus 로고    scopus 로고
    • MYC oncogenes and human neoplastic disease
    • DOI 10.1038/sj.onc.1202746
    • Nesbit CE, Tersak JM, Prochownik EV. MYC oncogenes and human neoplastic disease. Oncogene 1999; 18:3004-3016 (Pubitemid 29276540)
    • (1999) Oncogene , vol.18 , Issue.19 , pp. 3004-3016
    • Nesbit, C.E.1    Tersak, J.M.2    Prochownik, E.V.3
  • 8
    • 0034618402 scopus 로고    scopus 로고
    • A mutation in the c-myc-IRES leads to enhanced internal ribosome entry in multiple myeloma: A novel mechanism of oncogene de-regulation
    • Chappell SA, LeQuesne JP, Paulin FE, deSchoolmeester ML, Stoneley M, Soutar RL, et al. A mutation in the c-myc-IRES leads to enhanced internal ribosome entry in multiple myeloma: a novel mechanism of oncogene de-regulation. Oncogene 2000; 19:4437-4440
    • (2000) Oncogene , vol.19 , pp. 4437-4440
    • Chappell, S.A.1    LeQuesne, J.P.2    Paulin, F.E.3    DeSchoolmeester, M.L.4    Stoneley, M.5    Soutar, R.L.6
  • 9
    • 0028055178 scopus 로고
    • Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines
    • Albert T, Urlbauer B, Kohlhuber F, Hammersen B, Eick D. Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines. Oncogene 1994; 9:759-763 (Pubitemid 24065913)
    • (1994) Oncogene , vol.9 , Issue.3 , pp. 759-763
    • Albert, T.1    Urlbauer, B.2    Kohlhuber, F.3    Hammersen, B.4    Eick, D.5
  • 10
    • 0033081027 scopus 로고    scopus 로고
    • Destruction of Myc by ubiquitin-mediated proteolysis: Cancer-associated and transforming mutations stabilize Myc
    • DOI 10.1093/emboj/18.3.717
    • Salghetti SE, Kim SY, Tansey WP. Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc. EMBO J 1999; 18:717-726 (Pubitemid 29057256)
    • (1999) EMBO Journal , vol.18 , Issue.3 , pp. 717-726
    • Salghetti, S.E.1    Kim, S.Y.2    Tansey, W.P.3
  • 11
    • 0019504253 scopus 로고
    • Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis
    • DOI 10.1038/290475a0
    • Hayward WS, Neel BG, Astrin SM. Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis. Nature 1981; 290:475-480 (Pubitemid 11159077)
    • (1981) Nature , vol.290 , Issue.5806 , pp. 475-480
    • Hayward, W.S.1    Neel, B.G.2    Astrin, S.M.3
  • 12
    • 33845306813 scopus 로고    scopus 로고
    • NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
    • Palomero T, Lim WK, Odom DT, Sulis ML, Real PJ, Margolin A, et al. NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth. Proc Natl Acad Sci USA 2006; 103:18261-18266
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 18261-18266
    • Palomero, T.1    Lim, W.K.2    Odom, D.T.3    Sulis, M.L.4    Real, P.J.5    Margolin, A.6
  • 14
    • 18644373146 scopus 로고    scopus 로고
    • The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
    • van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, Hurlstone A, et al. The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell 2002; 111:241-250
    • (2002) Cell , vol.111 , pp. 241-250
    • Van De Wetering, M.1    Sancho, E.2    Verweij, C.3    De Lau, W.4    Oving, I.5    Hurlstone, A.6
  • 15
    • 2942668475 scopus 로고    scopus 로고
    • Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation and migration
    • Sansom OJ, Reed KR, Hayes AJ, Ireland H, Brinkmann H, Newton IP, et al. Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation and migration. Genes Dev 2004; 18:1385-1390
    • (2004) Genes Dev , vol.18 , pp. 1385-1390
    • Sansom, O.J.1    Reed, K.R.2    Hayes, A.J.3    Ireland, H.4    Brinkmann, H.5    Newton, I.P.6
  • 16
    • 0034054961 scopus 로고    scopus 로고
    • Axin and hepatocellular carcinomas
    • DOI 10.1038/73396
    • Clevers H. Axin and hepatocellular carcinomas. Nat Genet 2000; 24:206-208 (Pubitemid 30132183)
    • (2000) Nature Genetics , vol.24 , Issue.3 , pp. 206-208
    • Clevers, H.1
  • 17
    • 0037130449 scopus 로고    scopus 로고
    • Mutational spectrum of beta-catenin, AXIN1 and AXIN2 in hepatocellular carcinomas and hepatoblastomas
    • Taniguchi K, Roberts LR, Aderca IN, Dong X, Qian C, Murphy LM, et al. Mutational spectrum of beta-catenin, AXIN1 and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 2002; 21:4863-4871
    • (2002) Oncogene , vol.21 , pp. 4863-4871
    • Taniguchi, K.1    Roberts, L.R.2    Aderca, I.N.3    Dong, X.4    Qian, C.5    Murphy, L.M.6
  • 18
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev 2000; 14:1837-1851. (Pubitemid 30639518)
    • (2000) Genes and Development , vol.14 , Issue.15 , pp. 1837-1851
    • Polakis, P.1
  • 19
    • 33745026527 scopus 로고    scopus 로고
    • Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis
    • Veeck J, Niederacher D, An H, Klopocki E, Wiesmann F, Betz B, et al. Aberrant methylation of the Wnt antagonist SFRP1 in breast cancer is associated with unfavourable prognosis. Oncogene 2006; 25:3479-3488
    • (2006) Oncogene , vol.25 , pp. 3479-3488
    • Veeck, J.1    Niederacher, D.2    An, H.3    Klopocki, E.4    Wiesmann, F.5    Betz, B.6
  • 20
    • 34447530928 scopus 로고    scopus 로고
    • C-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1
    • DOI 10.1128/MCB.02282-06
    • Cowling VH, D'Cruz CM, Chodosh LA, Cole MD. c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1. Mol Cell Biol 2007; 27:5135-5146 (Pubitemid 47068288)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.14 , pp. 5135-5146
    • Cowling, V.H.1    D'Cruz, C.M.2    Chodosh, L.A.3    Cole, M.D.4
  • 22
    • 0028171968 scopus 로고
    • Mediation of c-myc-induced apoptosis by p53
    • Hermeking H, Eick D. Mediation of c-Myc-induced apoptosis by p53. Science 1994; 265:2091-2093 (Pubitemid 24325691)
    • (1994) Science , vol.265 , Issue.5181 , pp. 2091-2093
    • Hermeking, H.1    Eick, D.2
  • 23
    • 0036285034 scopus 로고    scopus 로고
    • C-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: A mechanism for oncogene-induced genetic instability
    • DOI 10.1016/S1097-2765(02)00520-8
    • Vafa O, Wade M, Kern S, Beeche M, Pandita TK, Hampton GM, et al. c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability. Mol Cell 2002; 9:1031-1044 (Pubitemid 34626672)
    • (2002) Molecular Cell , vol.9 , Issue.5 , pp. 1031-1044
    • Vafa, O.1    Wade, M.2    Kern, S.3    Beeche, M.4    Pandita, T.K.5    Hampton, G.M.6    Wahl, G.M.7
  • 25
    • 0033180211 scopus 로고    scopus 로고
    • Reversible tumorigenesis by MYC in hematopoietic lineages
    • DOI 10.1016/S1097-2765(00)80367-6
    • Felsher DW, Bishop JM. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell 1999; 4:199-207. (Pubitemid 29456888)
    • (1999) Molecular Cell , vol.4 , Issue.2 , pp. 199-207
    • Felsher, D.W.1    Bishop, J.M.2
  • 26
    • 33744907788 scopus 로고    scopus 로고
    • Bcl2 suppresses DNA repair by enhancing c-Myc transcriptional activity
    • DOI 10.1074/jbc.M511914200
    • Jin Z, May WS, Gao F, Flagg T, Deng X. Bcl2 suppresses DNA repair by enhancing c-Myc transcriptional activity. J Biol Chem 2006; 281:14446-14456 (Pubitemid 43848375)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.20 , pp. 14446-14456
    • Jin, Z.1    May, W.S.2    Gao, F.3    Flagg, T.4    Deng, X.5
  • 27
    • 33847013757 scopus 로고    scopus 로고
    • C-MYC Delays Prometaphase by Direct Transactivation of MAD2 and BubR1: Identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability
    • Menssen A, Epanchintsev A, Lodygin D, Rezaei N, Jung P, Verdoodt B, et al. c-MYC Delays Prometaphase by Direct Transactivation of MAD2 and BubR1: Identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability. Cell Cycle 2007; 6:339-352
    • (2007) Cell Cycle , vol.6 , pp. 339-352
    • Menssen, A.1    Epanchintsev, A.2    Lodygin, D.3    Rezaei, N.4    Jung, P.5    Verdoodt, B.6
  • 28
    • 33748145149 scopus 로고    scopus 로고
    • Mechanism of transcriptional activation by the Myc oncoproteins
    • DOI 10.1016/j.semcancer.2006.08.001, PII S1044579X06000678, 25 Years of ther c-Myc Oncogene
    • Cowling VH, Cole MD. Mechanism of transcriptional activation by the Myc oncoproteins. Semin Cancer Biol 2006; 16:242-252 (Pubitemid 44311041)
    • (2006) Seminars in Cancer Biology , vol.16 , Issue.4 , pp. 242-252
    • Cowling, V.H.1    Cole, M.D.2
  • 29
    • 33947285072 scopus 로고    scopus 로고
    • The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding
    • DOI 10.1128/MCB.01828-06
    • Cowling VH, Cole MD. The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding. Mol Cell Biol 2007; 27:2059-2073 (Pubitemid 46418464)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.6 , pp. 2059-2073
    • Cowling, V.H.1    Cole, M.D.2
  • 30
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • DOI 10.1038/nrm1703
    • Adhikary S, Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat Rev Mol Cell Biol 2005; 6:635-645 (Pubitemid 41081267)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.8 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 31
    • 0027431276 scopus 로고
    • A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation
    • Ayer DE, Eisenman RN. A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation. Genes Dev 1993; 7:2110-2119 (Pubitemid 23336138)
    • (1993) Genes and Development , vol.7 , Issue.11 , pp. 2110-2119
    • Ayer, D.E.1    Eisenman, R.N.2
  • 32
    • 0028905563 scopus 로고
    • Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
    • Ayer DE, Lawrence QA, Eisenman RN. Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3. Cell 1995; 80:767-776
    • (1995) Cell , vol.80 , pp. 767-776
    • Ayer, D.E.1    Lawrence, Q.A.2    Eisenman, R.N.3
  • 33
    • 0037330625 scopus 로고    scopus 로고
    • Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes
    • DOI 10.1016/S0014-4827(02)00020-4, PII S0014482702000204
    • Gartel AL, Shchors K. Mechanisms of c-myc-mediated transcriptional repression of growth arrest genes. Exp Cell Res 2003; 283:17-21. (Pubitemid 36259892)
    • (2003) Experimental Cell Research , vol.283 , Issue.1 , pp. 17-21
    • Gartel, A.L.1    Shchors, K.2
  • 34
    • 0024557039 scopus 로고
    • The "initiator" as a transcription control element
    • Smale ST, Baltimore D. The "initiator" as a transcription control element. Cell 1989; 57:103-113
    • (1989) Cell , vol.57 , pp. 103-113
    • Smale, S.T.1    Baltimore, D.2
  • 35
    • 0028169192 scopus 로고
    • C-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II
    • Li LH, Nerlov C, Prendergast G, MacGregor D, Ziff EB. c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. EMBO J 1994; 13:4070-4079 (Pubitemid 24275863)
    • (1994) EMBO Journal , vol.13 , Issue.17 , pp. 4070-4079
    • Li, L.-H.1    Nerlov, C.2    Prendergast, G.3    MacGregor, D.4    Ziff, E.B.5
  • 36
    • 0035967099 scopus 로고    scopus 로고
    • Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc
    • Yang W, Shen J, Wu M, Arsura M, FitzGerald M, Suldan Z, et al. Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc. Oncogene 2001; 20:1688-1702
    • (2001) Oncogene , vol.20 , pp. 1688-1702
    • Yang, W.1    Shen, J.2    Wu, M.3    Arsura, M.4    FitzGerald, M.5    Suldan, Z.6
  • 38
    • 0027745645 scopus 로고
    • Inhibition of transcriptipnal regulator Yin-Yang-1 by association with c-Myc
    • Shrivastava A, Saleque S, Kalpana GV, Artandi S, Goff SP, Calame K. Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc. Science 1993; 262:1889-1892. (Pubitemid 124000643)
    • (1993) Science , vol.262 , Issue.5141 , pp. 1889-1892
    • Shrivastava, A.1    Saleque, S.2    Kalpana, G.V.3    Artandi, S.4    Goff, S.P.5    Calame, K.6
  • 40
    • 0027425699 scopus 로고
    • Direct role for Myc in transcription initiation mediated by interactions with TFII-I
    • DOI 10.1038/365359a0
    • Roy AL, Carruthers C, Gutjahr T, Roeder RG. Direct role for Myc in transcription initiation mediated by interactions with TFII-I. Nature 1993; 365:359-361 (Pubitemid 23288980)
    • (1993) Nature , vol.365 , Issue.6444 , pp. 359-361
    • Roy, A.L.1    Carruthers, C.2    Gutjahr, T.3    Roeder, R.G.4
  • 44
    • 0023888953 scopus 로고
    • Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro
    • DOI 10.1038/332557a0
    • Mermod N, Williams TJ, Tjian R. Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro. Nature 1988; 332:557-561 (Pubitemid 18107927)
    • (1988) Nature , vol.332 , Issue.6164 , pp. 557-561
    • Mermod, N.1    Williams, T.J.2    Tjian, R.3
  • 45
    • 0025052367 scopus 로고
    • Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity
    • Hu YF, Luscher B, Admon A, Mermod N, Tjian R. Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity. Genes Dev 1990; 4:1741-1752 (Pubitemid 20352073)
    • (1990) Genes and Development , vol.4 , Issue.10 , pp. 1741-1752
    • Hu, Y.-F.1    Luscher, B.2    Admon, A.3    Mermod, N.4    Tjian, R.5
  • 47
    • 23044465261 scopus 로고    scopus 로고
    • Regulation of the expression of caspase-9 by the transcription factor activator protein-4 in glucocorticoid-induced apoptosis
    • DOI 10.1074/jbc.M501304200
    • Tsujimoto K, Ono T, Sato M, Nishida T, Oguma T, Tadakuma T. Regulation of the expression of caspase-9 by the transcription factor activator protein-4 in glucocorticoid-induced apoptosis. J Biol Chem 2005; 280:27638-27644 (Pubitemid 41076876)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.30 , pp. 27638-27644
    • Tsujimoto, K.1    Ono, T.2    Sato, M.3    Nishida, T.4    Oguma, T.5    Tadakuma, T.6
  • 48
    • 33748350491 scopus 로고    scopus 로고
    • A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells
    • Kim MY, Jeong BC, Lee JH, Kee HJ, Kook H, Kim NS, et al. A repressor complex, AP4 transcription factor and geminin, negatively regulates expression of target genes in nonneuronal cells. Proc Natl Acad Sci USA 2006; 103:13074-13079
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13074-13079
    • Kim, M.Y.1    Jeong, B.C.2    Lee, J.H.3    Kee, H.J.4    Kook, H.5    Kim, N.S.6
  • 49
    • 33744952170 scopus 로고    scopus 로고
    • Transcriptional repression of human immunodeficiency virus type 1 by AP-4
    • DOI 10.1074/jbc.M511773200
    • Imai K, Okamoto T. Transcriptional repression of human immunodeficiency virus type 1 by AP-4. J Biol Chem 2006; 281:12495-12505 (Pubitemid 43855336)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.18 , pp. 12495-12505
    • Imai, K.1    Okamoto, T.2
  • 50
    • 0032509332 scopus 로고    scopus 로고
    • Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression
    • DOI 10.1016/S0378-1119(98)00512-5, PII S0378111998005125
    • Cui Y, Narayanan CS, Zhou J, Kumar A. Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression. Gene 1998; 224:97-107. (Pubitemid 29023545)
    • (1998) Gene , vol.224 , Issue.1-2 , pp. 97-107
    • Cui, Y.1    Narayanan, C.S.2    Zhou, J.3    Kumar, A.4
  • 51
    • 0033551390 scopus 로고    scopus 로고
    • The Myc oncoprotein: A critical evaluation of transactivation and target gene regulation
    • DOI 10.1038/sj.onc.1202748
    • Cole MD, McMahon SB. The Myc oncoprotein: a critical evaluation of transactivation and target gene regulation. Oncogene 1999; 18:2916-2924 (Pubitemid 29276532)
    • (1999) Oncogene , vol.18 , Issue.19 , pp. 2916-2924
    • Cole, M.D.1    McMahon, S.B.2
  • 52
    • 0029002136 scopus 로고
    • A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
    • Littlewood TD, Hancock DC, Danielian PS, Parker MG, Evan GI. A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res 1995; 23:1686-1690
    • (1995) Nucleic Acids Res , vol.23 , pp. 1686-1690
    • Littlewood, T.D.1    Hancock, D.C.2    Danielian, P.S.3    Parker, M.G.4    Evan, G.I.5
  • 56
    • 34548118366 scopus 로고    scopus 로고
    • Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer
    • DOI 10.1016/j.ygyno.2007.05.009, PII S0090825807003411
    • Walker G, MacLeod K, Williams AR, Cameron DA, Smyth JF, Langdon SP. Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer. Gynecol Oncol 2007; 106:461-468 (Pubitemid 47302473)
    • (2007) Gynecologic Oncology , vol.106 , Issue.3 , pp. 461-468
    • Walker, G.1    MacLeod, K.2    Williams, A.R.W.3    Cameron, D.A.4    Smyth, J.F.5    Langdon, S.P.6
  • 57
    • 0026735224 scopus 로고
    • Mechanism of estrogen activation of c-myc oncogene expression
    • Dubik D, Shiu RP. Mechanism of estrogen activation of c-myc oncogene expression. Oncogene 1992; 7:1587-1594
    • (1992) Oncogene , vol.7 , pp. 1587-1594
    • Dubik, D.1    Shiu, R.P.2
  • 58
    • 23844465938 scopus 로고    scopus 로고
    • Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc
    • DOI 10.1128/MCB.25.17.7917-7925.2005
    • Rodrik V, Zheng Y, Harrow F, Chen Y, Foster DA. Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc. Mol Cell Biol 2005; 25:7917-7925 (Pubitemid 41170149)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.17 , pp. 7917-7925
    • Rodrik, V.1    Zheng, Y.2    Harrow, F.3    Chen, Y.4    Foster, D.A.5
  • 59
    • 18644371442 scopus 로고    scopus 로고
    • Negative regulation of the mammalian UV response by Myc through association with Miz-1
    • Herold S, Wanzel M, Beuger V, Frohme C, Beul D, Hillukkala T, et al. Negative regulation of the mammalian UV response by Myc through association with Miz-1. Mol Cell 2002; 10:509-521
    • (2002) Mol Cell , vol.10 , pp. 509-521
    • Herold, S.1    Wanzel, M.2    Beuger, V.3    Frohme, C.4    Beul, D.5    Hillukkala, T.6
  • 63
    • 27144462049 scopus 로고    scopus 로고
    • BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells
    • DOI 10.1038/ni1245, PII N1245
    • Phan RT, Saito M, Basso K, Niu H, Dalla-Favera R. BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells. Nat Immunol 2005; 6:1054-1060 (Pubitemid 41486191)
    • (2005) Nature Immunology , vol.6 , Issue.10 , pp. 1054-1060
    • Phan, R.T.1    Saito, M.2    Basso, K.3    Niu, H.4    Dalla-Favera, R.5
  • 65
    • 13444270415 scopus 로고    scopus 로고
    • Myc represses transcription through recruitment of DNA methyltransferase corepressor
    • Brenner C, Deplus R, Didelot C, Loriot A, Vire E, De Smet C, et al. Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J 2005; 24:336-346
    • (2005) EMBO J , vol.24 , pp. 336-346
    • Brenner, C.1    Deplus, R.2    Didelot, C.3    Loriot, A.4    Vire, E.5    De Smet, C.6
  • 66
    • 0030879868 scopus 로고    scopus 로고
    • Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins
    • Prabhu S, Ignatova A, Park ST, Sun XH. Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins. Mol Cell Biol 1997; 17:5888-5896 (Pubitemid 27411095)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.10 , pp. 5888-5896
    • Prabhu, S.1    Ignatova, A.2    Park, S.T.3    Sun, X.-H.4
  • 67
    • 1642303117 scopus 로고    scopus 로고
    • Cip1 Promoters Linking Differentiation and Cell Cycle Arrest in Neuroblastoma Cells
    • DOI 10.1128/MCB.24.7.2662-2672.2004
    • Liu Y, Encinas M, Comella JX, Aldea M, Gallego C. Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells. Mol Cell Biol 2004; 24:2662-2672 (Pubitemid 38381259)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.7 , pp. 2662-2672
    • Liu, Y.1    Encinas, M.2    Comella, J.X.3    Aldea, M.4    Gallego, C.5
  • 68
    • 0034662959 scopus 로고    scopus 로고
    • CIP1 by c-Myc in overcoming transforming growth factor beta-induced cell cycle arrest
    • CIP1 by c-Myc in overcoming transforming growth factor beta-induced cell cycle arrest. Proc Natl Acad Sci USA 2000; 97:9498-9503
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9498-9503
    • Claassen, G.F.1    Hann, S.R.2
  • 69
    • 0028053873 scopus 로고
    • Role of flanking e box motifs in human immunodeficiency virus type 1 TATA element function
    • Ou SH, Garcia-Martinez LF, Paulssen EJ, Gaynor RB. Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function. J Virol 1994; 68:7188-7199 (Pubitemid 24328771)
    • (1994) Journal of Virology , vol.68 , Issue.11 , pp. 7188-7199
    • Ou, S.-H.I.1    Garcia-Martinez, L.F.2    Paulssen, E.J.3    Gaynor, R.B.4
  • 70
    • 13944252067 scopus 로고    scopus 로고
    • The life cycle of c-Myc: From synthesis to degradation
    • Sears RC. The life cycle of C-myc: from synthesis to degradation. Cell Cycle 2004; 3:1133-1137 (Pubitemid 40268631)
    • (2004) Cell Cycle , vol.3 , Issue.9 , pp. 1133-1137
    • Sears, R.C.1
  • 72
    • 57449109370 scopus 로고    scopus 로고
    • Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation
    • Hui L, Zatloukal K, Scheuch H, Stepniak E, Wagner EF. Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation. J Clin Invest 2008; 118:3943-3953
    • (2008) J Clin Invest , vol.118 , pp. 3943-3953
    • Hui, L.1    Zatloukal, K.2    Scheuch, H.3    Stepniak, E.4    Wagner, E.F.5
  • 73
    • 0036606633 scopus 로고    scopus 로고
    • Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: Implications for the antiproliferative effects of antiestrogens
    • Carroll JS, Swarbrick A, Musgrove EA, Sutherland RL. Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens. Cancer Res 2002; 62:3126-3131 (Pubitemid 34602404)
    • (2002) Cancer Research , vol.62 , Issue.11 , pp. 3126-3131
    • Carroll, J.S.1    Swarbrick, A.2    Musgrove, E.A.3    Sutherland, R.L.4
  • 74
    • 24044525270 scopus 로고    scopus 로고
    • WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells
    • WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells. J Biol Chem 2005; 280:17617-17625
    • (2005) J Biol Chem , vol.280 , pp. 17617-17625
    • Mukherjee, S.1    Conrad, S.E.2
  • 75
    • 0036568506 scopus 로고    scopus 로고
    • C-myc gene expression alone is sufficient to confer resistance to antiestrogen in human breast cancer cells
    • DOI 10.1002/ijc.10269
    • Venditti M, Iwasiow B, Orr FW, Shiu RP. C-myc gene expression alone is sufficient to confer resistance to antiestrogen in human breast cancer cells. Int J Cancer 2002; 99:35-42. (Pubitemid 34273195)
    • (2002) International Journal of Cancer , vol.99 , Issue.1 , pp. 35-42
    • Venditti, M.1    Iwasiow, B.2    Orr, F.W.3    Shiu, R.P.C.4
  • 78
    • 0037067653 scopus 로고    scopus 로고
    • E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression
    • Chen CR, Kang Y, Siegel PM, Massague J. E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression. Cell 2002; 110:19-32.
    • (2002) Cell , vol.110 , pp. 19-32
    • Chen, C.R.1    Kang, Y.2    Siegel, P.M.3    Massague, J.4
  • 79
    • 0028168242 scopus 로고
    • P15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
    • DOI 10.1038/371257a0
    • Hannon GJ, Beach D. p15INK4B is a potential effector of TGFbeta-induced cell cycle arrest. Nature 1994; 371:257-261 (Pubitemid 2126463)
    • (1994) Nature , vol.371 , Issue.6494 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 80
    • 0029073142 scopus 로고
    • Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism
    • Datto MB, Li Y, Panus JF, Howe DJ, Xiong Y, Wang XF. Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc Natl Acad Sci USA 1995; 92:5545-5549
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5545-5549
    • Datto, M.B.1    Li, Y.2    Panus, J.F.3    Howe, D.J.4    Xiong, Y.5    Wang, X.F.6
  • 81
    • 0030978315 scopus 로고    scopus 로고
    • Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-β in cells lacking the CDK inhibitor p15
    • DOI 10.1038/387417a0
    • Iavarone A, Massague J. Repression of the CDK activator Cdc25A and cell cycle arrest by cytokine TGFbeta in cells lacking the CDK inhibitor p15. Nature 1997; 387:417-422 (Pubitemid 27227208)
    • (1997) Nature , vol.387 , Issue.6631 , pp. 417-422
    • Iavarone, A.1    Massague, J.2
  • 83
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer
    • Siegel PM, Massague J. Cytostatic and apoptotic actions of TGFbeta in homeostasis and cancer. Nat Rev Cancer 2003; 3:807-821 (Pubitemid 37376979)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.11 , pp. 807-820
    • Siegel, P.M.1    Massague, J.2
  • 84
    • 33846833986 scopus 로고    scopus 로고
    • The Morphogenetic Code and Colon Cancer Development
    • DOI 10.1016/j.ccr.2007.01.003, PII S1535610807000219
    • van den Brink GR, Offerhaus GJ. The morphogenetic code and colon cancer development. Cancer Cell 2007; 11:109-117 (Pubitemid 46209852)
    • (2007) Cancer Cell , vol.11 , Issue.2 , pp. 109-117
    • Van Den Brink, G.R.1    Offerhaus, G.J.2
  • 85
    • 0034644472 scopus 로고    scopus 로고
    • TGFbeta signaling in growth control, cancer and heritable disorders
    • Massague J, Blain SW, Lo RS. TGFbeta signaling in growth control, cancer and heritable disorders. Cell 2000; 103:295-309.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 86
    • 33751018274 scopus 로고    scopus 로고
    • Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc
    • Muncan V, Sansom OJ, Tertoolen L, Phesse TJ, Begthel H, Sancho E, et al. Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc. Mol Cell Biol 2006; 26:8418-8426
    • (2006) Mol Cell Biol , vol.26 , pp. 8418-8426
    • Muncan, V.1    Sansom, O.J.2    Tertoolen, L.3    Phesse, T.J.4    Begthel, H.5    Sancho, E.6
  • 88
    • 0029791681 scopus 로고    scopus 로고
    • P21/WAF1/CIP1 expression in normal mucosa and in adenomas and adenocarcinomas of the colon: Its relationship with differentiation
    • DOI 10.1002/(SICI)1096-9896(199607)179:3<248::AID-PATH571>3.0.CO;2- 6
    • Doglioni C, Pelosio P, Laurino L, Macri E, Meggiolaro E, Favretti F, et al. p21/WAF1/CIP1 expression in normal mucosa and in adenomas and adenocarcinomas of the colon: its relationship with differentiation. J Pathol 1996; 179:248-253 (Pubitemid 26266401)
    • (1996) Journal of Pathology , vol.179 , Issue.3 , pp. 248-253
    • Doglioni, C.1    Pelosio, P.2    Laurino, L.3    Macri, E.4    Meggiolaro, E.5    Favretti, F.6    Barbareschi, M.7
  • 90
    • 58349105417 scopus 로고    scopus 로고
    • Upregulation of activator protein-4 in human colorectal cancer with metastasis
    • Cao J, Tang M, Li WL, Du H, Tang WB, Wang H, et al. Upregulation of activator protein-4 in human colorectal cancer with metastasis. Int J Surg Pathol 2008; 17:16-21.
    • (2008) Int J Surg Pathol , vol.17 , pp. 16-21
    • Cao, J.1    Tang, M.2    Li, W.L.3    Du, H.4    Tang, W.B.5    Wang, H.6
  • 91
    • 0038047893 scopus 로고    scopus 로고
    • Microarray-based identification of differentially expressed growth- And metastasis-associated genes in pancreatic cancer
    • Friess H, Ding J, Kleeff J, Fenkell L, Rosinski JA, Guweidhi A, et al. Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer. Cell Mol Life Sci 2003; 60:1180-1199
    • (2003) Cell Mol Life Sci , vol.60 , pp. 1180-1199
    • Friess, H.1    Ding, J.2    Kleeff, J.3    Fenkell, L.4    Rosinski, J.A.5    Guweidhi, A.6
  • 92
    • 0037025201 scopus 로고    scopus 로고
    • Sustained loss of a neoplastic phenotype by brief inactivation of MYC
    • Jain M, Arvanitis C, Chu K, Dewey W, Leonhardt E, Trinh M, et al. Sustained loss of a neoplastic phenotype by brief inactivation of MYC. Science 2002; 297:102-104
    • (2002) Science , vol.297 , pp. 102-104
    • Jain, M.1    Arvanitis, C.2    Chu, K.3    Dewey, W.4    Leonhardt, E.5    Trinh, M.6
  • 93
    • 0037013147 scopus 로고    scopus 로고
    • Suppression of Myc-induced apoptosis in β cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression
    • DOI 10.1016/S0092-8674(02)00738-9
    • Pelengaris S, Khan M, Evan GI. Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell 2002; 109:321-334 (Pubitemid 34606875)
    • (2002) Cell , vol.109 , Issue.3 , pp. 321-334
    • Pelengaris, S.1    Khan, M.2    Evan, G.I.3
  • 94
    • 7744220635 scopus 로고    scopus 로고
    • MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer
    • Shachaf CM, Kopelman AM, Arvanitis C, Karlsson A, Beer S, Mandl S, et al. MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer. Nature 2004; 431:1112-1117
    • (2004) Nature , vol.431 , pp. 1112-1117
    • Shachaf, C.M.1    Kopelman, A.M.2    Arvanitis, C.3    Karlsson, A.4    Beer, S.5    Mandl, S.6
  • 96
    • 42149091567 scopus 로고    scopus 로고
    • Selective inhibition of c-Myc/Max dimerization by a pyrazolo[1,5-a] pyrimidine
    • Kiessling A, Wiesinger R, Sperl B, Berg T. Selective inhibition of c-Myc/Max dimerization by a pyrazolo[1,5-a]pyrimidine. Chem Med Chem 2007; 2:627-630
    • (2007) Chem Med Chem , vol.2 , pp. 627-630
    • Kiessling, A.1    Wiesinger, R.2    Sperl, B.3    Berg, T.4
  • 101
    • 34447137342 scopus 로고    scopus 로고
    • Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC
    • DOI 10.1038/nm1606, PII NM1606
    • Goga A, Yang D, Tward AD, Morgan DO, Bishop JM. Inhibition of CDK1 as a potential therapy for tumors overexpressing MYC. Nat Med 2007; 13:820-827 (Pubitemid 47038193)
    • (2007) Nature Medicine , vol.13 , Issue.7 , pp. 820-827
    • Goga, A.1    Yang, D.2    Tward, A.D.3    Morgan, D.O.4    Bishop, J.M.5
  • 102
    • 0037126303 scopus 로고    scopus 로고
    • Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage
    • DOI 10.1038/nature01119
    • Seoane J, Le HV, Massague J. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature 2002; 419:729-734 (Pubitemid 35177959)
    • (2002) Nature , vol.419 , Issue.6908 , pp. 729-734
    • Seoane, J.1    Le, H.-V.2    Massague, J.3
  • 103
    • 9244256816 scopus 로고    scopus 로고
    • 2-terminal kinase activity and mitochondrial death signaling
    • DOI 10.1158/0008-5472.CAN-04-2584
    • Lo PK, Huang SZ, Chen HC, Wang FF. The prosurvival activity of p53 protects cells from UV-induced apoptosis by inhibiting c-Jun NH2-terminal kinase activity and mitochondrial death signaling. Cancer Res 2004; 64:8736-8745 (Pubitemid 39552091)
    • (2004) Cancer Research , vol.64 , Issue.23 , pp. 8736-8745
    • Lo, P.-K.1    Huang, S.-Z.2    Chen, H.-C.3    Wang, F.-F.4
  • 104
    • 0033997563 scopus 로고    scopus 로고
    • Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs
    • Blagosklonny MV, Robey R, Bates S, Fojo T. Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs. J Clin Invest 2000; 105:533-539 (Pubitemid 30127254)
    • (2000) Journal of Clinical Investigation , vol.105 , Issue.4 , pp. 533-539
    • Blagosklonny, M.V.1    Robey, R.2    Bates, S.3    Fojo, T.4
  • 105
    • 0032553485 scopus 로고    scopus 로고
    • Requirement for p53 and p21 to sustain G2 arrest after DNA damage
    • Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998; 282:1497-1501
    • (1998) Science , vol.282 , pp. 1497-1501
    • Bunz, F.1    Dutriaux, A.2    Lengauer, C.3    Waldman, T.4    Zhou, S.5    Brown, J.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.