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Volumn 188, Issue 6, 2010, Pages 905-918

The Arf tumor suppressor protein inhibits Miz1 to suppress cell adhesion and induce apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; MIZ1 PROTEIN; MYC PROTEIN; NUCLEOPHOSMIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

EID: 77949689758     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200908103     Document Type: Article
Times cited : (35)

References (47)
  • 1
    • 1642499357 scopus 로고    scopus 로고
    • Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23
    • doi:10.1128/MCB.24.3.985- 996.2004
    • Bertwistle, D., M. Sugimoto, and C.J. Sherr. 2004. Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23. Mol. Cell. Biol. 24:985-996. doi:10.1128/MCB.24.3.985- 996.2004
    • (2004) Mol. Cell. Biol , vol.24 , pp. 985-996
    • Bertwistle, D.1    Sugimoto, M.2    Sherr, C.J.3
  • 2
    • 21244451434 scopus 로고    scopus 로고
    • ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor
    • doi:10.1016/j.cell.2005.03.037
    • Chen, D., N. Kon, M. Li, W. Zhang, J. Qin, and W. Gu. 2005. ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor. Cell. 121:1071-1083. doi:10.1016/j.cell.2005.03.037
    • (2005) Cell , vol.121 , pp. 1071-1083
    • Chen, D.1    Kon, N.2    Li, M.3    Zhang, W.4    Qin, J.5    Gu, W.6
  • 3
    • 0037019165 scopus 로고    scopus 로고
    • Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2
    • doi:10.1038/sj.onc.1205558
    • Clark, P.A., S. Llanos, and G. Peters. 2002. Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2. Oncogene. 21:4498-4507. doi:10.1038/sj.onc.1205558
    • (2002) Oncogene , vol.21 , pp. 4498-4507
    • Clark, P.A.1    Llanos, S.2    Peters, G.3
  • 5
    • 4344668161 scopus 로고    scopus 로고
    • Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc
    • doi:10.1074/jbc.M312305200
    • Datta, A., A. Nag, W. Pan, N. Hay, A.L. Gartel, O. Colamonici, Y. Mori, and P. Raychaudhuri. 2004. Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc. J. Biol. Chem. 279:36698-36707. doi:10.1074/jbc.M312305200
    • (2004) J. Biol. Chem , vol.279 , pp. 36698-36707
    • Datta, A.1    Nag, A.2    Pan, W.3    Hay, N.4    Gartel, A.L.5    Colamonici, O.6    Mori, Y.7    Raychaudhuri, P.8
  • 7
    • 54349087788 scopus 로고    scopus 로고
    • Myc's broad reach
    • doi:10.1101/gad.1712408
    • Eilers, M., and R.N. Eisenman. 2008. Myc's broad reach. Genes Dev. 22:2755-2766. doi:10.1101/gad.1712408
    • (2008) Genes Dev , vol.22 , pp. 2755-2766
    • Eilers, M.1    Eisenman, R.N.2
  • 8
    • 0042913170 scopus 로고    scopus 로고
    • Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment
    • doi:10.1242/dev.00462
    • Frye, M., C. Gardner, E.R. Li, I. Arnold, and F.M. Watt. 2003. Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment. Development. 130:2793-2808. doi:10.1242/dev.00462
    • (2003) Development , vol.130 , pp. 2793-2808
    • Frye, M.1    Gardner, C.2    Li, E.R.3    Arnold, I.4    Watt, F.M.5
  • 10
    • 40249105993 scopus 로고    scopus 로고
    • The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing
    • 9:273-279. doi:10.1038/embor. 2008.3
    • Haindl, M., T. Harasim, D. Eick, and S. Muller. 2008. The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing. EMBO Rep. 9:273-279. doi:10.1038/embor. 2008.3
    • (2008) EMBO Rep
    • Haindl, M.1    Harasim, T.2    Eick, D.3    Muller, S.4
  • 12
  • 13
    • 44449129539 scopus 로고    scopus 로고
    • Mitochondrial p32 is a critical mediator of ARF-induced apoptosis
    • doi:10.1016/j.ccr. 2008.04.002
    • Itahana, K., and Y. Zhang. 2008. Mitochondrial p32 is a critical mediator of ARF-induced apoptosis. Cancer Cell. 13:542-553. doi:10.1016/j.ccr. 2008.04.002
    • (2008) Cancer Cell , vol.13 , pp. 542-553
    • Itahana, K.1    Zhang, Y.2
  • 14
    • 0345276485 scopus 로고    scopus 로고
    • Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation
    • doi:10.1016/S1097-2765(03)00431-3
    • Itahana, K., K.P. Bhat, A. Jin, Y. Itahana, D. Hawke, R. Kobayashi, and Y. Zhang. 2003. Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation. Mol. Cell. 12:1151-1164. doi:10.1016/S1097-2765(03)00431-3
    • (2003) Mol. Cell , vol.12 , pp. 1151-1164
    • Itahana, K.1    Bhat, K.P.2    Jin, A.3    Itahana, Y.4    Hawke, D.5    Kobayashi, R.6    Zhang, Y.7
  • 15
    • 0030728468 scopus 로고    scopus 로고
    • Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
    • doi:10.1016/S0092-8674(00)80452-3
    • Kamijo, T., F. Zindy, M.F. Roussel, D.E. Quelle, J.R. Downing, R.A. Ashmun, G. Grosveld, and C.J. Sherr. 1997. Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell. 91:649-659. doi:10.1016/S0092-8674(00)80452-3
    • (1997) Cell , vol.91 , pp. 649-659
    • Kamijo, T.1    Zindy, F.2    Roussel, M.F.3    Quelle, D.E.4    Downing, J.R.5    Ashmun, R.A.6    Grosveld, G.7    Sherr, C.J.8
  • 16
    • 0032493350 scopus 로고    scopus 로고
    • Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
    • doi:10.1073/pnas.95.14.8292
    • Kamijo, T., J.D. Weber, G. Zambetti, F. Zindy, M.F. Roussel, and C.J. Sherr. 1998. Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proc. Natl. Acad. Sci. USA. 95:8292-8297. doi:10.1073/pnas.95.14.8292
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 8292-8297
    • Kamijo, T.1    Weber, J.D.2    Zambetti, G.3    Zindy, F.4    Roussel, M.F.5    Sherr, C.J.6
  • 17
    • 19344364856 scopus 로고    scopus 로고
    • p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways
    • doi:10.1371/journal.pbio.0020242
    • Kelly-Spratt, K.S., K.E. Gurley, Y. Yasui, and C.J. Kemp. 2004. p19Arf suppresses growth, progression, and metastasis of Hras-driven carcinomas through p53-dependent and -independent pathways. PLoS Biol. 2:E242. doi:10.1371/journal.pbio.0020242
    • (2004) PLoS Biol , vol.2
    • Kelly-Spratt, K.S.1    Gurley, K.E.2    Yasui, Y.3    Kemp, C.J.4
  • 19
    • 55849125016 scopus 로고    scopus 로고
    • Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3
    • Kuo, M.L., W. den Besten, M.C. Thomas, and C.J. Sherr. 2008. Arf-induced turnover of the nucleolar nucleophosmin-associated SUMO-2/3 protease Senp3. Cell Cycle. 7:3378-3387.
    • (2008) Cell Cycle , vol.7 , pp. 3378-3387
    • Kuo, M.L.1    den Besten, W.2    Thomas, M.C.3    Sherr, C.J.4
  • 20
    • 57749116048 scopus 로고    scopus 로고
    • Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation
    • doi:10.1073/pnas.0806879105
    • Li, Z., D. Boone, and S.R. Hann. 2008. Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation. Proc. Natl. Acad. Sci. USA. 105:18794-18799. doi:10.1073/pnas.0806879105
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 18794-18799
    • Li, Z.1    Boone, D.2    Hann, S.R.3
  • 22
    • 76349083381 scopus 로고    scopus 로고
    • Miao, L., Z. Song, L. Jin, Y.M. Zhu, L.P. Wen, and M. Wu. 2010. ARF antagonizes the ability of Miz-1 to inhibit p53-mediated transactivation. Oncogene. 29:711-722. doi:10.1038/onc.2009.372
    • Miao, L., Z. Song, L. Jin, Y.M. Zhu, L.P. Wen, and M. Wu. 2010. ARF antagonizes the ability of Miz-1 to inhibit p53-mediated transactivation. Oncogene. 29:711-722. doi:10.1038/onc.2009.372
  • 23
    • 0036896923 scopus 로고    scopus 로고
    • CD44 is required for two consecutive steps in HGF/c-Met signaling
    • doi:10.1101/gad.242602
    • Orian-Rousseau, V., L. Chen, J.P. Sleeman, P. Herrlich, and H. Ponta. 2002. CD44 is required for two consecutive steps in HGF/c-Met signaling. Genes Dev. 16:3074-3086. doi:10.1101/gad.242602
    • (2002) Genes Dev , vol.16 , pp. 3074-3086
    • Orian-Rousseau, V.1    Chen, L.2    Sleeman, J.P.3    Herrlich, P.4    Ponta, H.5
  • 24
    • 0036192061 scopus 로고    scopus 로고
    • The myc oncogene: MarvelouslY Complex
    • doi:10.1016/S0065- 230X(02)84004-0
    • Oster, S.K., C.S. Ho, E.L. Soucie, and L.Z. Penn. 2002. The myc oncogene: MarvelouslY Complex. Adv. Cancer Res. 84:81-154. doi:10.1016/S0065- 230X(02)84004-0
    • (2002) Adv. Cancer Res , vol.84 , pp. 81-154
    • Oster, S.K.1    Ho, C.S.2    Soucie, E.L.3    Penn, L.Z.4
  • 25
    • 64749093273 scopus 로고    scopus 로고
    • Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex
    • doi:10.1016/j.molcel. 2009.03.013
    • Ouyang, J., Y. Shi, A. Valin, Y. Xuan, and G. Gill. 2009. Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex. Mol. Cell. 34:145-154. doi:10.1016/j.molcel. 2009.03.013
    • (2009) Mol. Cell , vol.34 , pp. 145-154
    • Ouyang, J.1    Shi, Y.2    Valin, A.3    Xuan, Y.4    Gill, G.5
  • 26
    • 0036211680 scopus 로고    scopus 로고
    • Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines
    • doi:10.1016/S0165-4608(01)00575-1
    • Park, Y.B., M.J. Park, K. Kimura, K. Shimizu, S.H. Lee, and J. Yokota. 2002. Alterations in the INK4a/ARF locus and their effects on the growth of human osteosarcoma cell lines. Cancer Genet. Cytogenet. 133:105-111. doi:10.1016/S0165-4608(01)00575-1
    • (2002) Cancer Genet. Cytogenet , vol.133 , pp. 105-111
    • Park, Y.B.1    Park, M.J.2    Kimura, K.3    Shimizu, K.4    Lee, S.H.5    Yokota, J.6
  • 27
    • 33846948993 scopus 로고    scopus 로고
    • BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis
    • doi:10.1074/jbc.M609138200
    • Patel, J.H., and S.B. McMahon. 2007. BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis. J. Biol. Chem. 282:5-13. doi:10.1074/jbc.M609138200
    • (2007) J. Biol. Chem , vol.282 , pp. 5-13
    • Patel, J.H.1    McMahon, S.B.2
  • 28
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • doi:10.1073/pnas.90.18.8392
    • Pear, W.S., G.P. Nolan, M.L. Scott, and D. Baltimore. 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA. 90:8392-8396. doi:10.1073/pnas.90.18.8392
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 29
    • 0030799791 scopus 로고    scopus 로고
    • An alternative pathway for gene regulation by Myc
    • doi:10.1093/emboj/16.18.5672
    • Peukert, K., P. Staller, A. Schneider, G. Carmichael, F. Hänel, and M. Eilers. 1997. An alternative pathway for gene regulation by Myc. EMBO J. 16:5672-5686. doi:10.1093/emboj/16.18.5672
    • (1997) EMBO J , vol.16 , pp. 5672-5686
    • Peukert, K.1    Staller, P.2    Schneider, A.3    Carmichael, G.4    Hänel, F.5    Eilers, M.6
  • 30
    • 6044254972 scopus 로고    scopus 로고
    • p19ARF directly and differentially controls the functions of c-Myc independently of p53
    • doi:10.1038/nature02958
    • Qi, Y., M.A. Gregory, Z. Li, J.P. Brousal, K. West, and S.R. Hann. 2004. p19ARF directly and differentially controls the functions of c-Myc independently of p53. Nature. 431:712-717. doi:10.1038/nature02958
    • (2004) Nature , vol.431 , pp. 712-717
    • Qi, Y.1    Gregory, M.A.2    Li, Z.3    Brousal, J.P.4    West, K.5    Hann, S.R.6
  • 31
    • 0029587551 scopus 로고
    • Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
    • doi:10.1016/0092-8674(95)90214-7
    • Quelle, D.E., F. Zindy, R.A. Ashmun, and C.J. Sherr. 1995. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell. 83:993-1000. doi:10.1016/0092-8674(95)90214-7
    • (1995) Cell , vol.83 , pp. 993-1000
    • Quelle, D.E.1    Zindy, F.2    Ashmun, R.A.3    Sherr, C.J.4
  • 33
    • 0033081027 scopus 로고    scopus 로고
    • Destruction of Myc by ubiquitin-mediated proteolysis: Cancer-associated and transforming mutations stabilize Myc
    • doi:10.1093/emboj/18.3.717
    • Salghetti, S.E., S.Y. Kim, and W.P. Tansey. 1999. Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc. EMBO J. 18:717-726. doi:10.1093/emboj/18.3.717
    • (1999) EMBO J , vol.18 , pp. 717-726
    • Salghetti, S.E.1    Kim, S.Y.2    Tansey, W.P.3
  • 34
    • 0034744956 scopus 로고    scopus 로고
    • TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b
    • doi:10.1038/35070086
    • Seoane, J., C. Pouponnot, P. Staller, M. Schader, M. Eilers, and J. Massagué. 2001. TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b. Nat. Cell Biol. 3:400-408. doi:10.1038/35070086
    • (2001) Nat. Cell Biol , vol.3 , pp. 400-408
    • Seoane, J.1    Pouponnot, C.2    Staller, P.3    Schader, M.4    Eilers, M.5    Massagué, J.6
  • 35
    • 0037126303 scopus 로고    scopus 로고
    • Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage
    • doi:10.1038/nature01119
    • Seoane, J., H.V. Le, and J. Massagué. 2002. Myc suppression of the p21(Cip1) Cdk inhibitor influences the outcome of the p53 response to DNA damage. Nature. 419:729-734. doi:10.1038/nature01119
    • (2002) Nature , vol.419 , pp. 729-734
    • Seoane, J.1    Le, H.V.2    Massagué, J.3
  • 37
    • 40849150778 scopus 로고    scopus 로고
    • Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNAi screen
    • doi:10.1016/j.molcel.2007.12.032
    • Stielow, B., A. Sapetschnig, I. Krüger, N. Kunert, A. Brehm, M. Boutros, and G. Suske. 2008. Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNAi screen. Mol. Cell. 29:742-754. doi:10.1016/j.molcel.2007.12.032
    • (2008) Mol. Cell , vol.29 , pp. 742-754
    • Stielow, B.1    Sapetschnig, A.2    Krüger, I.3    Kunert, N.4    Brehm, A.5    Boutros, M.6    Suske, G.7
  • 38
    • 0032169516 scopus 로고    scopus 로고
    • The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
    • doi:10.1093/emboj/17.17.5001
    • Stott, F.J., S. Bates, M.C. James, B.B. McConnell, M. Starborg, S. Brookes, I. Palmero, K. Ryan, E. Hara, K.H. Vousden, and G. Peters. 1998. The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 17:5001-5014. doi:10.1093/emboj/17.17.5001
    • (1998) EMBO J , vol.17 , pp. 5001-5014
    • Stott, F.J.1    Bates, S.2    James, M.C.3    McConnell, B.B.4    Starborg, M.5    Brookes, S.6    Palmero, I.7    Ryan, K.8    Hara, E.9    Vousden, K.H.10    Peters, G.11
  • 39
    • 19644384513 scopus 로고    scopus 로고
    • Sumoylation induced by the Arf tumor suppressor: A p53-independent function
    • doi:10.1073/pnas.0502978102
    • Tago, K., S. Chiocca, and C.J. Sherr. 2005. Sumoylation induced by the Arf tumor suppressor: a p53-independent function. Proc. Natl. Acad. Sci. USA. 102:7689-7694. doi:10.1073/pnas.0502978102
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 7689-7694
    • Tago, K.1    Chiocca, S.2    Sherr, C.J.3
  • 40
    • 51049097902 scopus 로고    scopus 로고
    • A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth
    • doi:10.1038/ncb1764
    • Wanzel, M., A.C. Russ, D. Kleine-Kohlbrecher, E. Colombo, P.G. Pelicci, and M. Eilers. 2008. A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth. Nat. Cell Biol. 10:1051-1061. doi:10.1038/ncb1764
    • (2008) Nat. Cell Biol , vol.10 , pp. 1051-1061
    • Wanzel, M.1    Russ, A.C.2    Kleine-Kohlbrecher, D.3    Colombo, E.4    Pelicci, P.G.5    Eilers, M.6
  • 42
    • 30344478870 scopus 로고    scopus 로고
    • A global map of p53 transcription-factor binding sites in the human genome
    • doi:10.1016/j.cell.2005.10.043
    • Wei, C.L., Q. Wu, V.B. Vega, K.P. Chiu, P. Ng, T. Zhang, A. Shahab, H.C. Yong, Y. Fu, Z. Weng, et al. 2006. A global map of p53 transcription-factor binding sites in the human genome. Cell. 124:207-219. doi:10.1016/j.cell.2005.10.043
    • (2006) Cell , vol.124 , pp. 207-219
    • Wei, C.L.1    Wu, Q.2    Vega, V.B.3    Chiu, K.P.4    Ng, P.5    Zhang, T.6    Shahab, A.7    Yong, H.C.8    Fu, Y.9    Weng, Z.10
  • 43
    • 12344330424 scopus 로고    scopus 로고
    • limmaGUI: A graphical user interface for linear modeling of microarray data
    • doi:10.1093/bioinformatics/bth449
    • Wettenhall, J.M., and G.K. Smyth. 2004. limmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics. 20:3705-3706. doi:10.1093/bioinformatics/bth449
    • (2004) Bioinformatics , vol.20 , pp. 3705-3706
    • Wettenhall, J.M.1    Smyth, G.K.2
  • 45
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
    • doi:10.1016/S0092- 8674(00)81401-4
    • Zhang, Y., Y. Xiong, and W.G. Yarbrough. 1998. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell. 92:725-734. doi:10.1016/S0092- 8674(00)81401-4
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 46
    • 0032145569 scopus 로고    scopus 로고
    • Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
    • doi:10.1101/gad.12.15.2424
    • Zindy, F., C.M. Eischen, D.H. Randle, T. Kamijo, J.L. Cleveland, C.J. Sherr, and M.F. Roussel. 1998. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev. 12:2424-2433. doi:10.1101/gad.12.15.2424
    • (1998) Genes Dev , vol.12 , pp. 2424-2433
    • Zindy, F.1    Eischen, C.M.2    Randle, D.H.3    Kamijo, T.4    Cleveland, J.L.5    Sherr, C.J.6    Roussel, M.F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.