메뉴 건너뛰기




Volumn 22, Issue , 2014, Pages 165-174

TopBP1: A BRCT-scaffold protein functioning in multiple cellular pathways

Author keywords

Scaffold proteins; TopBP1 functions in checkpoint signalling; TopBP1 functions in replication; TopBP1 review

Indexed keywords

ATR PROTEIN; CELL PROTEIN; SCAFFOLD PROTEIN; TOPBP1 PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; DNA BINDING PROTEIN; NUCLEAR PROTEIN; TOPBP1 PROTEIN, HUMAN;

EID: 84923331549     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2014.06.004     Document Type: Review
Times cited : (97)

References (118)
  • 1
    • 0015049534 scopus 로고
    • The isolation and genetic classification of UV-sensitive mutants of Schizosaccharomyces pombe
    • Schupbach M. The isolation and genetic classification of UV-sensitive mutants of Schizosaccharomyces pombe. Mutat. Res. 1971, 11:361-371.
    • (1971) Mutat. Res. , vol.11 , pp. 361-371
    • Schupbach, M.1
  • 2
    • 0001503931 scopus 로고
    • Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesis
    • Hirano T., Funahashi S., Uemura T., Yanagida M. Isolation and characterization of Schizosaccharomyces pombe cutmutants that block nuclear division but not cytokinesis. EMBO J. 1986, 5:2973-2979.
    • (1986) EMBO J. , vol.5 , pp. 2973-2979
    • Hirano, T.1    Funahashi, S.2    Uemura, T.3    Yanagida, M.4
  • 3
    • 0027176343 scopus 로고
    • Fission yeast cut5+, required for S phase onset and M phase restraint, is identical to the radiation-damage repair gene rad4+
    • Saka Y., Yanagida M. Fission yeast cut5+, required for S phase onset and M phase restraint, is identical to the radiation-damage repair gene rad4+. Cell 1993, 74:383-393.
    • (1993) Cell , vol.74 , pp. 383-393
    • Saka, Y.1    Yanagida, M.2
  • 4
    • 0026344528 scopus 로고
    • Cloning and characterization of the rad4 gene of Schizosaccharomyces pombe; a gene showing short regions of sequence similarity to the human XRCC1 gene
    • Fenech M., Carr A.M., Murray J., Watts F.Z., Lehmann A.R. Cloning and characterization of the rad4 gene of Schizosaccharomyces pombe; a gene showing short regions of sequence similarity to the human XRCC1 gene. Nucleic Acids Res. 1991, 19:6737-6741.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 6737-6741
    • Fenech, M.1    Carr, A.M.2    Murray, J.3    Watts, F.Z.4    Lehmann, A.R.5
  • 5
    • 0027487240 scopus 로고
    • Duplicated region of sequence similarity to the human XRCC1 DNA repair gene in the Schizosaccharomyces pombe rad4/cut5 gene
    • Lehmann A.R. Duplicated region of sequence similarity to the human XRCC1 DNA repair gene in the Schizosaccharomyces pombe rad4/cut5 gene. Nucleic Acids Res. 1993, 21:5274.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 5274
    • Lehmann, A.R.1
  • 6
    • 0030187780 scopus 로고    scopus 로고
    • BRCA1 protein products. . .Functional motifs
    • Koonin E.V., Altschul S.F., Bork P. BRCA1 protein products. . .Functional motifs. Nat. Genet. 1996, 13:266-268.
    • (1996) Nat. Genet. , vol.13 , pp. 266-268
    • Koonin, E.V.1    Altschul, S.F.2    Bork, P.3
  • 7
    • 27544460716 scopus 로고    scopus 로고
    • Identification and functional analysis of TopBP1 and its homologs
    • Garcia V., Furuya K., Carr A.M. Identification and functional analysis of TopBP1 and its homologs. DNA Repair (Amst) 2005, 4:1227-1239.
    • (2005) DNA Repair (Amst) , vol.4 , pp. 1227-1239
    • Garcia, V.1    Furuya, K.2    Carr, A.M.3
  • 8
    • 0029592020 scopus 로고
    • Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint
    • Araki H., Leem S.H., Phongdara A., Sugino A. Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:11791-11795.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 11791-11795
    • Araki, H.1    Leem, S.H.2    Phongdara, A.3    Sugino, A.4
  • 9
    • 0031574247 scopus 로고    scopus 로고
    • A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator
    • Yamane K., Kawabata M., Tsuruo T. A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell-cycle regulator. Eur. J. Biochem. 1997, 250:794-799.
    • (1997) Eur. J. Biochem. , vol.250 , pp. 794-799
    • Yamane, K.1    Kawabata, M.2    Tsuruo, T.3
  • 10
    • 0033793764 scopus 로고    scopus 로고
    • The Drosophila mus101 gene, which links DNA repair, replication and condensation of heterochromatin in mitosis, encodes a protein with seven BRCA1 C-terminus domains
    • Yamamoto R.R., Axton J.M., Yamamoto Y., Saunders R.D., Glover D.M., Henderson D.S. The Drosophila mus101 gene, which links DNA repair, replication and condensation of heterochromatin in mitosis, encodes a protein with seven BRCA1 C-terminus domains. Genetics 2000, 156:711-721.
    • (2000) Genetics , vol.156 , pp. 711-721
    • Yamamoto, R.R.1    Axton, J.M.2    Yamamoto, Y.3    Saunders, R.D.4    Glover, D.M.5    Henderson, D.S.6
  • 11
    • 79953139076 scopus 로고    scopus 로고
    • TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells
    • Jeon Y., Ko E., Lee K.Y., Ko M.J., Park S.Y., Kang J., Jeon C.H., Lee H., Hwang D.S. TopBP1 deficiency causes an early embryonic lethality and induces cellular senescence in primary cells. J. Biol. Chem. 2011, 286:5414-5422.
    • (2011) J. Biol. Chem. , vol.286 , pp. 5414-5422
    • Jeon, Y.1    Ko, E.2    Lee, K.Y.3    Ko, M.J.4    Park, S.Y.5    Kang, J.6    Jeon, C.H.7    Lee, H.8    Hwang, D.S.9
  • 12
    • 0142147272 scopus 로고    scopus 로고
    • The BRCT domain is a phospho-protein binding domain
    • Yu X., Chini C.C., He M., Mer G., Chen J. The BRCT domain is a phospho-protein binding domain. Science 2003, 302:639-642.
    • (2003) Science , vol.302 , pp. 639-642
    • Yu, X.1    Chini, C.C.2    He, M.3    Mer, G.4    Chen, J.5
  • 13
    • 78651321775 scopus 로고    scopus 로고
    • Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1
    • Rappas M., Oliver A.W., Pearl L.H. Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1. Nucleic Acids Res. 2011, 39:313-324.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 313-324
    • Rappas, M.1    Oliver, A.W.2    Pearl, L.H.3
  • 15
    • 0034809456 scopus 로고    scopus 로고
    • Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1
    • Williams R.S., Green R., Glover J.N. Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1. Nat. Struct. Biol. 2001, 8:838-842.
    • (2001) Nat. Struct. Biol. , vol.8 , pp. 838-842
    • Williams, R.S.1    Green, R.2    Glover, J.N.3
  • 16
    • 48749102974 scopus 로고    scopus 로고
    • Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair
    • Kilkenny M.L., Dore A.S., Roe S.M., Nestoras K., Ho J.C., Watts F.Z., Pearl L.H. Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair. Genes Dev. 2008, 22:2034-2047.
    • (2008) Genes Dev. , vol.22 , pp. 2034-2047
    • Kilkenny, M.L.1    Dore, A.S.2    Roe, S.M.3    Nestoras, K.4    Ho, J.C.5    Watts, F.Z.6    Pearl, L.H.7
  • 17
    • 79953020734 scopus 로고    scopus 로고
    • Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
    • Leung C.C., Gong Z., Chen J., Glover J.N. Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control. J. Biol. Chem. 2011, 286:4292-4301.
    • (2011) J. Biol. Chem. , vol.286 , pp. 4292-4301
    • Leung, C.C.1    Gong, Z.2    Chen, J.3    Glover, J.N.4
  • 18
    • 84881481957 scopus 로고    scopus 로고
    • Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control
    • Leung C.C., Sun L., Gong Z., Burkat M., Edwards R., Assmus M., Chen J., Glover J.N. Structural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control. Structure 2013, 21:1450-1459.
    • (2013) Structure , vol.21 , pp. 1450-1459
    • Leung, C.C.1    Sun, L.2    Gong, Z.3    Burkat, M.4    Edwards, R.5    Assmus, M.6    Chen, J.7    Glover, J.N.8
  • 19
    • 75149150495 scopus 로고    scopus 로고
    • Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1
    • Leung C.C., Kellogg E., Kuhnert A., Hanel F., Baker D., Glover J.N. Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIbeta binding protein 1. Protein Sci. 2010, 19:162-167.
    • (2010) Protein Sci. , vol.19 , pp. 162-167
    • Leung, C.C.1    Kellogg, E.2    Kuhnert, A.3    Hanel, F.4    Baker, D.5    Glover, J.N.6
  • 20
    • 33644757806 scopus 로고    scopus 로고
    • TopBP1 activates the ATR-ATRIP complex
    • Kumagai A., Lee J., Yoo H.Y., Dunphy W.G. TopBP1 activates the ATR-ATRIP complex. Cell 2006, 124:943-955.
    • (2006) Cell , vol.124 , pp. 943-955
    • Kumagai, A.1    Lee, J.2    Yoo, H.Y.3    Dunphy, W.G.4
  • 22
    • 44849093460 scopus 로고    scopus 로고
    • TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
    • Mordes D.A., Glick G.G., Zhao R., Cortez D. TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev. 2008, 22:1478-1489.
    • (2008) Genes Dev. , vol.22 , pp. 1478-1489
    • Mordes, D.A.1    Glick, G.G.2    Zhao, R.3    Cortez, D.4
  • 24
    • 0034028908 scopus 로고    scopus 로고
    • Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast
    • Masumoto H., Sugino A., Araki H. Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast. Mol. Cell. Biol. 2000, 20:2809-2817.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 2809-2817
    • Masumoto, H.1    Sugino, A.2    Araki, H.3
  • 25
    • 0037900888 scopus 로고    scopus 로고
    • Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication
    • Hashimoto Y., Takisawa H. Xenopus Cut5 is essential for a CDK-dependent process in the initiation of DNA replication. EMBO J. 2003, 22:2526-2535.
    • (2003) EMBO J. , vol.22 , pp. 2526-2535
    • Hashimoto, Y.1    Takisawa, H.2
  • 26
    • 33646578509 scopus 로고    scopus 로고
    • A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11
    • Tak Y.S., Tanaka Y., Endo S., Kamimura Y., Araki H. A CDK-catalysed regulatory phosphorylation for formation of the DNA replication complex Sld2-Dpb11. EMBO J. 2006, 25:1987-1996.
    • (2006) EMBO J. , vol.25 , pp. 1987-1996
    • Tak, Y.S.1    Tanaka, Y.2    Endo, S.3    Kamimura, Y.4    Araki, H.5
  • 27
    • 33846328709 scopus 로고    scopus 로고
    • Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast
    • Zegerman P., Diffley J.F. Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast. Nature 2007, 445:281-285.
    • (2007) Nature , vol.445 , pp. 281-285
    • Zegerman, P.1    Diffley, J.F.2
  • 28
    • 0037034048 scopus 로고    scopus 로고
    • S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast
    • Masumoto H., Muramatsu S., Kamimura Y., Araki H. S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast. Nature 2002, 415:651-655.
    • (2002) Nature , vol.415 , pp. 651-655
    • Masumoto, H.1    Muramatsu, S.2    Kamimura, Y.3    Araki, H.4
  • 29
    • 80053329001 scopus 로고    scopus 로고
    • Initiation of chromosomal DNA replication in eukaryotic cells; contribution of yeast genetics to the elucidation
    • Araki H. Initiation of chromosomal DNA replication in eukaryotic cells; contribution of yeast genetics to the elucidation. Genes Genet. Syst. 2011, 86:141-149.
    • (2011) Genes Genet. Syst. , vol.86 , pp. 141-149
    • Araki, H.1
  • 30
    • 33749345709 scopus 로고    scopus 로고
    • Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins
    • Yabuuchi H., Yamada Y., Uchida T., Sunathvanichkul T., Nakagawa T., Masukata H. Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins. EMBO J. 2006, 25:4663-4674.
    • (2006) EMBO J. , vol.25 , pp. 4663-4674
    • Yabuuchi, H.1    Yamada, Y.2    Uchida, T.3    Sunathvanichkul, T.4    Nakagawa, T.5    Masukata, H.6
  • 31
    • 79959957543 scopus 로고    scopus 로고
    • Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases
    • Heller R.C., Kang S., Lam W.M., Chen S., Chan C.S., Bell S.P. Eukaryotic origin-dependent DNA replication in vitro reveals sequential action of DDK and S-CDK kinases. Cell 2011, 146:80-91.
    • (2011) Cell , vol.146 , pp. 80-91
    • Heller, R.C.1    Kang, S.2    Lam, W.M.3    Chen, S.4    Chan, C.S.5    Bell, S.P.6
  • 32
    • 33745925880 scopus 로고    scopus 로고
    • Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase
    • Moyer S.E., Lewis P.W., Botchan M.R. Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:10236-10241.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 10236-10241
    • Moyer, S.E.1    Lewis, P.W.2    Botchan, M.R.3
  • 33
    • 84880662044 scopus 로고    scopus 로고
    • Efficient initiation of DNA replication in eukaryotes requires Dpb11/TopBP1-GINS interaction
    • Tanaka S., Komeda Y., Umemori T., Kubota Y., Takisawa H., Araki H. Efficient initiation of DNA replication in eukaryotes requires Dpb11/TopBP1-GINS interaction. Mol. Cell. Biol. 2013, 33:2614-2622.
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 2614-2622
    • Tanaka, S.1    Komeda, Y.2    Umemori, T.3    Kubota, Y.4    Takisawa, H.5    Araki, H.6
  • 34
    • 80054685862 scopus 로고    scopus 로고
    • Enabling association of the GINS protein tetramer with the mini chromosome maintenance (Mcm)2-7 protein complex by phosphorylated Sld2 protein and single-stranded origin DNA
    • Bruck I., Kanter D.M., Kaplan D.L. Enabling association of the GINS protein tetramer with the mini chromosome maintenance (Mcm)2-7 protein complex by phosphorylated Sld2 protein and single-stranded origin DNA. J. Biol. Chem. 2011, 286:36414-36426.
    • (2011) J. Biol. Chem. , vol.286 , pp. 36414-36426
    • Bruck, I.1    Kanter, D.M.2    Kaplan, D.L.3
  • 35
    • 79956327961 scopus 로고    scopus 로고
    • Origin single-stranded DNA releases Sld3 protein from the Mcm2-7 complex, allowing the GINS tetramer to bind the Mcm2-7 complex
    • Bruck I., Kaplan D.L. Origin single-stranded DNA releases Sld3 protein from the Mcm2-7 complex, allowing the GINS tetramer to bind the Mcm2-7 complex. J. Biol. Chem. 2011, 286:18602-18613.
    • (2011) J. Biol. Chem. , vol.286 , pp. 18602-18613
    • Bruck, I.1    Kaplan, D.L.2
  • 36
    • 79960334083 scopus 로고    scopus 로고
    • CDK promotes interactions of Sld3 and Drc1 with Cut5 for initiation of DNA replication in fission yeast
    • Fukuura M., Nagao K., Obuse C., Takahashi T.S., Nakagawa T., Masukata H. CDK promotes interactions of Sld3 and Drc1 with Cut5 for initiation of DNA replication in fission yeast. Mol. Biol. Cell 2011, 22:2620-2633.
    • (2011) Mol. Biol. Cell , vol.22 , pp. 2620-2633
    • Fukuura, M.1    Nagao, K.2    Obuse, C.3    Takahashi, T.S.4    Nakagawa, T.5    Masukata, H.6
  • 37
    • 80054757845 scopus 로고    scopus 로고
    • Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1)
    • Taylor M., Moore K., Murray J., Aves S.J., Price C. Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair (Amst.) 2011, 10:1154-1163.
    • (2011) DNA Repair (Amst.) , vol.10 , pp. 1154-1163
    • Taylor, M.1    Moore, K.2    Murray, J.3    Aves, S.J.4    Price, C.5
  • 39
    • 33745471225 scopus 로고    scopus 로고
    • The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication
    • Matsuno K., Kumano M., Kubota Y., Hashimoto Y., Takisawa H. The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication. Mol. Cell. Biol. 2006, 26:4843-4852.
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 4843-4852
    • Matsuno, K.1    Kumano, M.2    Kubota, Y.3    Hashimoto, Y.4    Takisawa, H.5
  • 40
    • 75749103708 scopus 로고    scopus 로고
    • Treslin collaborates with TopBP1 in triggering the initiation of DNA replication
    • Kumagai A., Shevchenko A., Dunphy W.G. Treslin collaborates with TopBP1 in triggering the initiation of DNA replication. Cell 2010, 140:349-359.
    • (2010) Cell , vol.140 , pp. 349-359
    • Kumagai, A.1    Shevchenko, A.2    Dunphy, W.G.3
  • 42
    • 79959399046 scopus 로고    scopus 로고
    • Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication
    • Kumagai A., Shevchenko A., Shevchenko A., Dunphy W.G. Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication. J. Cell Biol. 2011, 193:995-1007.
    • (2011) J. Cell Biol. , vol.193 , pp. 995-1007
    • Kumagai, A.1    Shevchenko, A.2    Shevchenko, A.3    Dunphy, W.G.4
  • 45
    • 84894073887 scopus 로고    scopus 로고
    • CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans
    • Gaggioli V., Zeiser E., Rivers D., Bradshaw C.R., Ahringer J., Zegerman P. CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans. J. Cell Biol. 2014, 204:507-522.
    • (2014) J. Cell Biol. , vol.204 , pp. 507-522
    • Gaggioli, V.1    Zeiser, E.2    Rivers, D.3    Bradshaw, C.R.4    Ahringer, J.5    Zegerman, P.6
  • 46
    • 0032497529 scopus 로고    scopus 로고
    • Rad53-dependent checkpoint controls late-firing origins of DNA replication
    • Santocanale C., Diffley J.F., Mec1- A. Rad53-dependent checkpoint controls late-firing origins of DNA replication. Nature 1998, 395:615-618.
    • (1998) Nature , vol.395 , pp. 615-618
    • Santocanale, C.1    Diffley, J.F.2    Mec1, A.3
  • 50
    • 77957149919 scopus 로고    scopus 로고
    • Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation
    • Zegerman P., Diffley J.F. Checkpoint-dependent inhibition of DNA replication initiation by Sld3 and Dbf4 phosphorylation. Nature 2010, 467:474-478.
    • (2010) Nature , vol.467 , pp. 474-478
    • Zegerman, P.1    Diffley, J.F.2
  • 51
    • 84882919775 scopus 로고    scopus 로고
    • Titration of four replication factors is essential for the Xenopus laevis midblastula transition
    • Collart C., Allen G.E., Bradshaw C.R., Smith J.C., Zegerman P. Titration of four replication factors is essential for the Xenopus laevis midblastula transition. Science 2013, 341:893-896.
    • (2013) Science , vol.341 , pp. 893-896
    • Collart, C.1    Allen, G.E.2    Bradshaw, C.R.3    Smith, J.C.4    Zegerman, P.5
  • 52
    • 82455164158 scopus 로고    scopus 로고
    • Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast
    • Mantiero D., Mackenzie A., Donaldson A., Zegerman P. Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast. EMBO J. 2011, 30:4805-4814.
    • (2011) EMBO J. , vol.30 , pp. 4805-4814
    • Mantiero, D.1    Mackenzie, A.2    Donaldson, A.3    Zegerman, P.4
  • 53
    • 2442646547 scopus 로고    scopus 로고
    • Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1
    • Furuya K., Poitelea M., Guo L., Caspari T., Carr A.M. Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1. Genes Dev. 2004, 18:1154-1164.
    • (2004) Genes Dev. , vol.18 , pp. 1154-1164
    • Furuya, K.1    Poitelea, M.2    Guo, L.3    Caspari, T.4    Carr, A.M.5
  • 54
    • 33746597380 scopus 로고    scopus 로고
    • Rad4TopBP1, a scaffold protein, plays separate roles in DNA damage and replication checkpoints and DNA replication
    • Taricani L., Wang T.S. Rad4TopBP1, a scaffold protein, plays separate roles in DNA damage and replication checkpoints and DNA replication. Mol. Biol. Cell 2006, 17:3456-3468.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 3456-3468
    • Taricani, L.1    Wang, T.S.2
  • 55
    • 79451472566 scopus 로고    scopus 로고
    • Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination
    • Germann S.M., Oestergaard V.H., Haas C., Salis P., Motegi A., Lisby M. Dpb11/TopBP1 plays distinct roles in DNA replication, checkpoint response and homologous recombination. DNA Repair (Amst.) 2011, 10:210-224.
    • (2011) DNA Repair (Amst.) , vol.10 , pp. 210-224
    • Germann, S.M.1    Oestergaard, V.H.2    Haas, C.3    Salis, P.4    Motegi, A.5    Lisby, M.6
  • 56
    • 83555168211 scopus 로고    scopus 로고
    • Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment
    • Pfander B., Diffley J.F. Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment. EMBO J. 2011, 30:4897-4907.
    • (2011) EMBO J. , vol.30 , pp. 4897-4907
    • Pfander, B.1    Diffley, J.F.2
  • 58
    • 0042941728 scopus 로고    scopus 로고
    • HRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II beta binding protein 1 focus formation
    • Greer D.A., Besley B.D., Kennedy K.B., Davey S. hRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II beta binding protein 1 focus formation. Cancer Res. 2003, 63:4829-4835.
    • (2003) Cancer Res. , vol.63 , pp. 4829-4835
    • Greer, D.A.1    Besley, B.D.2    Kennedy, K.B.3    Davey, S.4
  • 60
    • 84876097735 scopus 로고    scopus 로고
    • A role for the MRN complex in ATR activation via TOPBP1 recruitment
    • Duursma A.M., Driscoll R., Elias J.E., Cimprich K.A. A role for the MRN complex in ATR activation via TOPBP1 recruitment. Mol. Cell 2013, 50:116-122.
    • (2013) Mol. Cell , vol.50 , pp. 116-122
    • Duursma, A.M.1    Driscoll, R.2    Elias, J.E.3    Cimprich, K.A.4
  • 61
    • 84877156564 scopus 로고    scopus 로고
    • The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks
    • Lee J., Dunphy W.G. The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks. Mol. Biol. Cell 2013, 24:1343-1353.
    • (2013) Mol. Biol. Cell , vol.24 , pp. 1343-1353
    • Lee, J.1    Dunphy, W.G.2
  • 63
    • 79851488587 scopus 로고    scopus 로고
    • CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts
    • Ramirez-Lugo J.S., Yoo H.Y., Yoon S.J., Dunphy W.G. CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts. Cell Cycle 2011, 10:469-480.
    • (2011) Cell Cycle , vol.10 , pp. 469-480
    • Ramirez-Lugo, J.S.1    Yoo, H.Y.2    Yoon, S.J.3    Dunphy, W.G.4
  • 64
    • 0036134979 scopus 로고    scopus 로고
    • A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival
    • Yamane K., Wu X., Chen J. A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival. Mol. Cell Biol. 2002, 22:555-566.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 555-566
    • Yamane, K.1    Wu, X.2    Chen, J.3
  • 65
    • 79955516080 scopus 로고    scopus 로고
    • MDC1 collaborates with TopBP1 in DNA replication checkpoint control
    • Wang J., Gong Z., Chen J. MDC1 collaborates with TopBP1 in DNA replication checkpoint control. J. Cell Biol. 2011, 193:267-273.
    • (2011) J. Cell Biol. , vol.193 , pp. 267-273
    • Wang, J.1    Gong, Z.2    Chen, J.3
  • 66
    • 78149284014 scopus 로고    scopus 로고
    • TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint
    • Cescutti R., Negrini S., Kohzaki M., Halazonetis T.D. TopBP1 functions with 53BP1 in the G1 DNA damage checkpoint. EMBO J. 2010, 29:3723-3732.
    • (2010) EMBO J. , vol.29 , pp. 3723-3732
    • Cescutti, R.1    Negrini, S.2    Kohzaki, M.3    Halazonetis, T.D.4
  • 67
    • 0031438163 scopus 로고    scopus 로고
    • Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1
    • Saka Y., Esashi F., Matsusaka T., Mochida S., Yanagida M. Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1. Genes Dev. 1997, 11:3387-3400.
    • (1997) Genes Dev. , vol.11 , pp. 3387-3400
    • Saka, Y.1    Esashi, F.2    Matsusaka, T.3    Mochida, S.4    Yanagida, M.5
  • 68
    • 33745137149 scopus 로고    scopus 로고
    • Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks
    • Du L.L., Nakamura T.M., Russell P. Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. Genes Dev. 2006, 20:1583-1596.
    • (2006) Genes Dev. , vol.20 , pp. 1583-1596
    • Du, L.L.1    Nakamura, T.M.2    Russell, P.3
  • 69
    • 84864577748 scopus 로고    scopus 로고
    • Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint
    • Qu M., Yang B., Tao L., Yates J.R., Russell P., Dong M.Q., Du L.L. Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint. PLoS Genet. 2012, 8:e1002817.
    • (2012) PLoS Genet. , vol.8 , pp. e1002817
    • Qu, M.1    Yang, B.2    Tao, L.3    Yates, J.R.4    Russell, P.5    Dong, M.Q.6    Du, L.L.7
  • 72
    • 77955476243 scopus 로고    scopus 로고
    • DNA damage signaling recruits the Rtt107-Slx4 scaffolds via Dpb11 to mediate replication stress response
    • Ohouo P.Y., Bastos de Oliveira F.M., Almeida B.S., Smolka M.B. DNA damage signaling recruits the Rtt107-Slx4 scaffolds via Dpb11 to mediate replication stress response. Mol. Cell 2010, 39:300-306.
    • (2010) Mol. Cell , vol.39 , pp. 300-306
    • Ohouo, P.Y.1    Bastos de Oliveira, F.M.2    Almeida, B.S.3    Smolka, M.B.4
  • 73
    • 84871787877 scopus 로고    scopus 로고
    • DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9
    • Ohouo P.Y., Bastos de Oliveira F.M., Liu Y., Ma C.J., Smolka M.B. DNA-repair scaffolds dampen checkpoint signalling by counteracting the adaptor Rad9. Nature 2013, 493:120-124.
    • (2013) Nature , vol.493 , pp. 120-124
    • Ohouo, P.Y.1    Bastos de Oliveira, F.M.2    Liu, Y.3    Ma, C.J.4    Smolka, M.B.5
  • 74
    • 33646119403 scopus 로고    scopus 로고
    • Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling
    • Yan S., Lindsay H.D., Michael W.M. Direct requirement for Xmus101 in ATR-mediated phosphorylation of Claspin bound Chk1 during checkpoint signaling. J. Cell Biol. 2006, 173:181-186.
    • (2006) J. Cell Biol. , vol.173 , pp. 181-186
    • Yan, S.1    Lindsay, H.D.2    Michael, W.M.3
  • 75
    • 84873707924 scopus 로고    scopus 로고
    • WD40-repeat protein WDR18 collaborates with TopBP1 to facilitate DNA damage checkpoint signaling
    • Yan S., Willis J. WD40-repeat protein WDR18 collaborates with TopBP1 to facilitate DNA damage checkpoint signaling. Biochem. Biophys. Res. Commun. 2013, 431:466-471.
    • (2013) Biochem. Biophys. Res. Commun. , vol.431 , pp. 466-471
    • Yan, S.1    Willis, J.2
  • 76
    • 75949092280 scopus 로고    scopus 로고
    • BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control
    • Gong Z., Kim J.E., Leung C.C., Glover J.N., Chen J. BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control. Mol. Cell 2010, 37:438-446.
    • (2010) Mol. Cell , vol.37 , pp. 438-446
    • Gong, Z.1    Kim, J.E.2    Leung, C.C.3    Glover, J.N.4    Chen, J.5
  • 78
    • 34250705797 scopus 로고    scopus 로고
    • The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
    • Delacroix S., Wagner J.M., Kobayashi M., Yamamoto K., Karnitz L.M. The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev. 2007, 21:1472-1477.
    • (2007) Genes Dev. , vol.21 , pp. 1472-1477
    • Delacroix, S.1    Wagner, J.M.2    Kobayashi, M.3    Yamamoto, K.4    Karnitz, L.M.5
  • 79
    • 79957624098 scopus 로고    scopus 로고
    • Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1)
    • Lindsey-Boltz L.A., Sancar A. Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1). J. Biol. Chem. 2011, 286:19229-19236.
    • (2011) J. Biol. Chem. , vol.286 , pp. 19229-19236
    • Lindsey-Boltz, L.A.1    Sancar, A.2
  • 81
    • 58149102035 scopus 로고    scopus 로고
    • Yeast DNA replication protein Dpb11 activates the Mec1/ATR checkpoint kinase
    • Navadgi-Patil V.M., Burgers P.M. Yeast DNA replication protein Dpb11 activates the Mec1/ATR checkpoint kinase. J. Biol. Chem. 2008, 283:35853-35859.
    • (2008) J. Biol. Chem. , vol.283 , pp. 35853-35859
    • Navadgi-Patil, V.M.1    Burgers, P.M.2
  • 82
    • 33845607102 scopus 로고    scopus 로고
    • The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint
    • Majka J., Niedziela-Majka A., Burgers P.M. The checkpoint clamp activates Mec1 kinase during initiation of the DNA damage checkpoint. Mol. Cell 2006, 24:891-901.
    • (2006) Mol. Cell , vol.24 , pp. 891-901
    • Majka, J.1    Niedziela-Majka, A.2    Burgers, P.M.3
  • 83
    • 84873521523 scopus 로고    scopus 로고
    • Lagging strand maturation factor Dna2 is a component of the replication checkpoint initiation machinery
    • Kumar S., Burgers P.M. Lagging strand maturation factor Dna2 is a component of the replication checkpoint initiation machinery. Genes Dev. 2013, 27:313-321.
    • (2013) Genes Dev. , vol.27 , pp. 313-321
    • Kumar, S.1    Burgers, P.M.2
  • 84
    • 81755189059 scopus 로고    scopus 로고
    • The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint
    • Navadgi-Patil V.M., Kumar S., Burgers P.M. The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint. J. Biol. Chem. 2011, 286:40999-41007.
    • (2011) J. Biol. Chem. , vol.286 , pp. 40999-41007
    • Navadgi-Patil, V.M.1    Kumar, S.2    Burgers, P.M.3
  • 85
    • 84884614941 scopus 로고    scopus 로고
    • An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence
    • Zhou Z.W., Liu C., Li T.L., Bruhn C., Krueger A., Min W., Wang Z.Q., Carr A.M. An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence. PLoS Genet. 2013, 9:e1003702.
    • (2013) PLoS Genet. , vol.9 , pp. e1003702
    • Zhou, Z.W.1    Liu, C.2    Li, T.L.3    Bruhn, C.4    Krueger, A.5    Min, W.6    Wang, Z.Q.7    Carr, A.M.8
  • 86
    • 84874197336 scopus 로고    scopus 로고
    • NBS1 directly activates ATR independently of MRE11 and TOPBP1
    • Kobayashi M., Hayashi N., Takata M., Yamamoto K. NBS1 directly activates ATR independently of MRE11 and TOPBP1. Genes Cells 2013, 18:238-246.
    • (2013) Genes Cells , vol.18 , pp. 238-246
    • Kobayashi, M.1    Hayashi, N.2    Takata, M.3    Yamamoto, K.4
  • 87
    • 34547115962 scopus 로고    scopus 로고
    • Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM
    • Yoo H.Y., Kumagai A., Shevchenko A., Shevchenko A., Dunphy W.G. Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM. J. Biol. Chem. 2007, 282:17501-17506.
    • (2007) J. Biol. Chem. , vol.282 , pp. 17501-17506
    • Yoo, H.Y.1    Kumagai, A.2    Shevchenko, A.3    Shevchenko, A.4    Dunphy, W.G.5
  • 88
    • 44849128194 scopus 로고    scopus 로고
    • How ATR turns on: TopBP1 goes on ATRIP with ATR
    • Burrows A.E., Elledge S.J. How ATR turns on: TopBP1 goes on ATRIP with ATR. Genes Dev. 2008, 22:1416-1421.
    • (2008) Genes Dev. , vol.22 , pp. 1416-1421
    • Burrows, A.E.1    Elledge, S.J.2
  • 89
    • 33746234714 scopus 로고    scopus 로고
    • Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair
    • Ogiwara H., Ui A., Onoda F., Tada S., Enomoto T., Seki M. Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair. Nucleic Acids Res. 2006, 34:3389-3398.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 3389-3398
    • Ogiwara, H.1    Ui, A.2    Onoda, F.3    Tada, S.4    Enomoto, T.5    Seki, M.6
  • 90
    • 79952768906 scopus 로고    scopus 로고
    • Real-time analysis of double-strand DNA break repair by homologous recombination
    • Hicks W.M., Yamaguchi M., Haber J.E. Real-time analysis of double-strand DNA break repair by homologous recombination. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:3108-3115.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 3108-3115
    • Hicks, W.M.1    Yamaguchi, M.2    Haber, J.E.3
  • 91
    • 77953076932 scopus 로고    scopus 로고
    • Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly
    • Lydeard J.R., Lipkin-Moore Z., Sheu Y.J., Stillman B., Burgers P.M., Haber J.E. Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes Dev. 2010, 24:1133-1144.
    • (2010) Genes Dev. , vol.24 , pp. 1133-1144
    • Lydeard, J.R.1    Lipkin-Moore, Z.2    Sheu, Y.J.3    Stillman, B.4    Burgers, P.M.5    Haber, J.E.6
  • 93
    • 84890241687 scopus 로고    scopus 로고
    • TopBP1 controls BLM protein level to maintain genome stability
    • Wang J., Chen J., Gong Z. TopBP1 controls BLM protein level to maintain genome stability. Mol. Cell 2013, 52:667-678.
    • (2013) Mol. Cell , vol.52 , pp. 667-678
    • Wang, J.1    Chen, J.2    Gong, Z.3
  • 95
    • 33845774351 scopus 로고    scopus 로고
    • TopBP1 contains a transcriptional activation domain suppressed by two adjacent BRCT domains
    • Wright R.H., Dornan E.S., Donaldson M.M., Morgan I.M. TopBP1 contains a transcriptional activation domain suppressed by two adjacent BRCT domains. Biochem. J. 2006, 400:573-582.
    • (2006) Biochem. J. , vol.400 , pp. 573-582
    • Wright, R.H.1    Dornan, E.S.2    Donaldson, M.M.3    Morgan, I.M.4
  • 96
    • 0035878122 scopus 로고    scopus 로고
    • Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation
    • Lin W.C., Lin F.T., Nevins J.R. Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev. 2001, 15:1833-1844.
    • (2001) Genes Dev. , vol.15 , pp. 1833-1844
    • Lin, W.C.1    Lin, F.T.2    Nevins, J.R.3
  • 97
    • 36148957893 scopus 로고    scopus 로고
    • The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription
    • Sjottem E., Rekdal C., Svineng G., Johnsen S.S., Klenow H., Uglehus R.D., Johansen T. The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription. Nucleic Acids Res. 2007, 35:6648-6662.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 6648-6662
    • Sjottem, E.1    Rekdal, C.2    Svineng, G.3    Johnsen, S.S.4    Klenow, H.5    Uglehus, R.D.6    Johansen, T.7
  • 98
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin X.Q., Livingston D.M., Kaelin W.G., Adams P.D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:10918-10922.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 10918-10922
    • Qin, X.Q.1    Livingston, D.M.2    Kaelin, W.G.3    Adams, P.D.4
  • 99
    • 0028222124 scopus 로고
    • P53 and E2F-1 cooperate to mediate apoptosis
    • Wu X., Levine A.J. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. U.S.A. 1994, 91:3602-3606.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 3602-3606
    • Wu, X.1    Levine, A.J.2
  • 101
    • 1842831271 scopus 로고    scopus 로고
    • TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival
    • Liu K., Luo Y., Lin F.T., Lin W.C. TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival. Genes Dev. 2004, 18:673-686.
    • (2004) Genes Dev. , vol.18 , pp. 673-686
    • Liu, K.1    Luo, Y.2    Lin, F.T.3    Lin, W.C.4
  • 102
    • 0345352653 scopus 로고    scopus 로고
    • Regulation of E2F1 by BRCT domain-containing protein TopBP1
    • Liu K., Lin F.T., Ruppert J.M., Lin W.C. Regulation of E2F1 by BRCT domain-containing protein TopBP1. Mol. Cell. Biol. 2003, 23:3287-3304.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 3287-3304
    • Liu, K.1    Lin, F.T.2    Ruppert, J.M.3    Lin, W.C.4
  • 103
    • 84891709489 scopus 로고    scopus 로고
    • Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization
    • Liu K., Graves J.D., Scott J.D., Li R., Lin W.C. Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization. Mol. Cell. Biol. 2013, 33:4685-4700.
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 4685-4700
    • Liu, K.1    Graves, J.D.2    Scott, J.D.3    Li, R.4    Lin, W.C.5
  • 104
    • 33750209770 scopus 로고    scopus 로고
    • Regulation of TopBP1 oligomerization by Akt/PKB for cell survival
    • Liu K., Paik J.C., Wang B., Lin F.T., Lin W.C. Regulation of TopBP1 oligomerization by Akt/PKB for cell survival. EMBO J. 2006, 25:4795-4807.
    • (2006) EMBO J. , vol.25 , pp. 4795-4807
    • Liu, K.1    Paik, J.C.2    Wang, B.3    Lin, F.T.4    Lin, W.C.5
  • 106
    • 23144464363 scopus 로고    scopus 로고
    • Transcriptional regulation and transformation by Myc proteins
    • Adhikary S., Eilers M. Transcriptional regulation and transformation by Myc proteins. Nat. Rev. Mol. Cell Biol. 2005, 6:635-645.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 635-645
    • Adhikary, S.1    Eilers, M.2
  • 108
    • 34347397000 scopus 로고    scopus 로고
    • Human TopBP1 participates in cyclin E/CDK2 activation and preinitiation complex assembly during G1/S transition
    • Jeon Y., Lee K.Y., Ko M.J., Lee Y.S., Kang S., Hwang D.S. Human TopBP1 participates in cyclin E/CDK2 activation and preinitiation complex assembly during G1/S transition. J. Biol. Chem. 2007, 282:14882-14890.
    • (2007) J. Biol. Chem. , vol.282 , pp. 14882-14890
    • Jeon, Y.1    Lee, K.Y.2    Ko, M.J.3    Lee, Y.S.4    Kang, S.5    Hwang, D.S.6
  • 109
    • 34548490924 scopus 로고    scopus 로고
    • The DNA topoisomerase IIbeta binding protein 1 (TopBP1) interacts with poly (ADP-ribose) polymerase (PARP-1)
    • Wollmann Y., Schmidt U., Wieland G.D., Zipfel P.F., Saluz H.P., Hanel F. The DNA topoisomerase IIbeta binding protein 1 (TopBP1) interacts with poly (ADP-ribose) polymerase (PARP-1). J. Cell. Biochem. 2007, 102:171-182.
    • (2007) J. Cell. Biochem. , vol.102 , pp. 171-182
    • Wollmann, Y.1    Schmidt, U.2    Wieland, G.D.3    Zipfel, P.F.4    Saluz, H.P.5    Hanel, F.6
  • 110
    • 0036891226 scopus 로고    scopus 로고
    • Novel cellular interacting partners of the human papillomavirus 16 transcription/replication factor E2
    • Boner W., Morgan I.M. Novel cellular interacting partners of the human papillomavirus 16 transcription/replication factor E2. Virus Res. 2002, 90:113-118.
    • (2002) Virus Res. , vol.90 , pp. 113-118
    • Boner, W.1    Morgan, I.M.2
  • 111
    • 0037151001 scopus 로고    scopus 로고
    • A Functional interaction between the human papillomavirus 16 transcription/replication factor E2 and the DNA damage response protein TopBP1
    • Boner W., Taylor E.R., Tsirimonaki E., Yamane K., Campo M.S., Morgan I.M. A Functional interaction between the human papillomavirus 16 transcription/replication factor E2 and the DNA damage response protein TopBP1. J. Biol. Chem. 2002, 277:22297-22303.
    • (2002) J. Biol. Chem. , vol.277 , pp. 22297-22303
    • Boner, W.1    Taylor, E.R.2    Tsirimonaki, E.3    Yamane, K.4    Campo, M.S.5    Morgan, I.M.6
  • 116
    • 33748985129 scopus 로고    scopus 로고
    • Identification of a common polymorphism in the TopBP1 gene associated with hereditary susceptibility to breast and ovarian cancer
    • Karppinen S.M., Erkko H., Reini K., Pospiech H., Heikkinen K., Rapakko K., Syvaoja J.E., Winqvist R. Identification of a common polymorphism in the TopBP1 gene associated with hereditary susceptibility to breast and ovarian cancer. Eur. J. Cancer 2006, 42:2647-2652.
    • (2006) Eur. J. Cancer , vol.42 , pp. 2647-2652
    • Karppinen, S.M.1    Erkko, H.2    Reini, K.3    Pospiech, H.4    Heikkinen, K.5    Rapakko, K.6    Syvaoja, J.E.7    Winqvist, R.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.