-
1
-
-
0029592020
-
Dpb11, which interacts with DNA polymerase II(ε) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint
-
Araki, H., S.-H. Leem, A. Phongdara, and A. Sugino. 1995. Dpb11, which interacts with DNA polymerase II(ε) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint. Proc. Natl. Acad. Sci. USA 92:11791-11795.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 11791-11795
-
-
Araki, H.1
Leem, S.-H.2
Phongdara, A.3
Sugino, A.4
-
2
-
-
3142534591
-
Initiating cellular stress responses
-
Bakkenist, C. J., and M. B. Kastan. 2004. Initiating cellular stress responses. Cell 118:9-17.
-
(2004)
Cell
, vol.118
, pp. 9-17
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
3
-
-
33644774596
-
TOPping up ATR activity
-
Bartek, J., and N. Mailand. 2006. TOPping up ATR activity. Cell 124:888-890.
-
(2006)
Cell
, vol.124
, pp. 888-890
-
-
Bartek, J.1
Mailand, N.2
-
4
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan, M. V., J. Lee, I. M. Ward, J. E. Kim, J. R. Thompson, J. Chen, and G. Mer. 2006. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127:1361-1373.
-
(2006)
Cell
, vol.127
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
5
-
-
0037027880
-
DNA structure dependent checkpoints as regulators of DNA repair
-
Carr, A. M. 2002. DNA structure dependent checkpoints as regulators of DNA repair. DNA Repair 1:983-994.
-
(2002)
DNA Repair
, vol.1
, pp. 983-994
-
-
Carr, A.M.1
-
6
-
-
34250705797
-
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
-
Delacroix, S., J. M. Wagner, M. Kobayashi, K. Yamamoto, and L. M. Karnitz. 2007. The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev. 21:1472-1477.
-
(2007)
Genes Dev
, vol.21
, pp. 1472-1477
-
-
Delacroix, S.1
Wagner, J.M.2
Kobayashi, M.3
Yamamoto, K.4
Karnitz, L.M.5
-
7
-
-
33745137149
-
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks
-
Du, L. L., T. M. Nakamura, and P. Russell. 2006. Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. Genes Dev. 20:1583-1596.
-
(2006)
Genes Dev
, vol.20
, pp. 1583-1596
-
-
Du, L.L.1
Nakamura, T.M.2
Russell, P.3
-
8
-
-
2442646547
-
Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1
-
Furuya, K., M. Poitelea, L. Guo, T. Caspari, and A. M. Carr. 2004. Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BRCT domains of Rad4TOPBP1. Genes Dev. 18:1154-1164.
-
(2004)
Genes Dev
, vol.18
, pp. 1154-1164
-
-
Furuya, K.1
Poitelea, M.2
Guo, L.3
Caspari, T.4
Carr, A.M.5
-
9
-
-
27544460716
-
Identification and functional analysis of TopBP1 and its homologs
-
Garcia, V., K. Furuya, and A. M. Carr. 2005. Identification and functional analysis of TopBP1 and its homologs. DNA Repair 4:1227-1239.
-
(2005)
DNA Repair
, vol.4
, pp. 1227-1239
-
-
Garcia, V.1
Furuya, K.2
Carr, A.M.3
-
10
-
-
1542320702
-
Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint
-
Giannattasio, M., F. Lazzaro, M. P. Longhese, P. Plevani, and M. Muzi-Falconi. 2004. Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint. EMBO J. 23:429-438.
-
(2004)
EMBO J
, vol.23
, pp. 429-438
-
-
Giannattasio, M.1
Lazzaro, F.2
Longhese, M.P.3
Plevani, P.4
Muzi-Falconi, M.5
-
11
-
-
15444373985
-
The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1
-
Giannattasio, M., F. Lazzaro, P. Plevani, and M. Muzi-Falconi. 2005. The DNA damage checkpoint response requires histone H2B ubiquitination by Rad6-Bre1 and H3 methylation by Dot1. J. Biol. Chem. 280:9879-9886.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 9879-9886
-
-
Giannattasio, M.1
Lazzaro, F.2
Plevani, P.3
Muzi-Falconi, M.4
-
12
-
-
0034881760
-
Budding yeast Rad9 is an ATP-dependent Rad53 activating machine
-
Gilbert, C. S., C. M. Green, and N. F. Lowndes. 2001. Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. Mol. Cell 8:129-136.
-
(2001)
Mol. Cell
, vol.8
, pp. 129-136
-
-
Gilbert, C.S.1
Green, C.M.2
Lowndes, N.F.3
-
13
-
-
33847247383
-
Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain
-
Grenon, M., T. Costelloe, S. Jimeno, A. O'Shaughnessy, J. Fitzgerald, O. Zgheib, L. Degerth, and N. F. Lowndes. 2007. Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain. Yeast 24:105-119.
-
(2007)
Yeast
, vol.24
, pp. 105-119
-
-
Grenon, M.1
Costelloe, T.2
Jimeno, S.3
O'Shaughnessy, A.4
Fitzgerald, J.5
Zgheib, O.6
Degerth, L.7
Lowndes, N.F.8
-
14
-
-
35548970638
-
-
1 checkpoint in budding yeast. EMBO Rep. 8:851-857.
-
1 checkpoint in budding yeast. EMBO Rep. 8:851-857.
-
-
-
-
15
-
-
33747493040
-
The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1
-
Hashimoto, Y., T. Tsujimura, A. Sugino, and H. Takisawa. 2006. The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1. Genes Cells 11:993-1007.
-
(2006)
Genes Cells
, vol.11
, pp. 993-1007
-
-
Hashimoto, Y.1
Tsujimura, T.2
Sugino, A.3
Takisawa, H.4
-
16
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen, Y., O. Zgheib, R. A. Ditullio, Jr., V. G. Gorgoulis, P. Zacharatos, T. J. Petty, E. A. Sheston, H. S. Meliert, E. S. Stavridi, and T. D. Halazonetis. 2004. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 432:406-411.
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio Jr., R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Meliert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
17
-
-
27644467857
-
Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae
-
Hyland, E. M., M. S. Cosgrove, H. Molina, D. Wang, A. Pandey, R. J. Cottee, and J. D. Boeke. 2005. Insights into the role of histone H3 and histone H4 core modifiable residues in Saccharomyces cerevisiae. Mol. Cell. Biol. 25:10060-10070.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 10060-10070
-
-
Hyland, E.M.1
Cosgrove, M.S.2
Molina, H.3
Wang, D.4
Pandey, A.5
Cottee, R.J.6
Boeke, J.D.7
-
19
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan, M. B., and J. Bartek. 2004. Cell-cycle checkpoints and cancer. Nature 432:316-323.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
20
-
-
0033826256
-
Type B histone acetyltransferase Hat1p participates in telomeric silencing
-
Kelly, T. J., S. Qin, D. E. Gottschling, and M. R. Parthun. 2000. Type B histone acetyltransferase Hat1p participates in telomeric silencing. Mol. Cell. Biol. 20:7051-7058.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 7051-7058
-
-
Kelly, T.J.1
Qin, S.2
Gottschling, D.E.3
Parthun, M.R.4
-
21
-
-
33644757806
-
TopBP1 activates the ATR-ATRIP complex
-
Kumagai, A., J. Lee, H. Y. Yoo, and W. G. Dunphy. 2006. TopBP1 activates the ATR-ATRIP complex. Cell 124:943-955.
-
(2006)
Cell
, vol.124
, pp. 943-955
-
-
Kumagai, A.1
Lee, J.2
Yoo, H.Y.3
Dunphy, W.G.4
-
22
-
-
0036591878
-
The many faces of histone lysine methylation
-
Lachner, M., and T. Jenuwein. 2002. The many faces of histone lysine methylation. Curr. Opin. Cell Biol. 14:286-298.
-
(2002)
Curr. Opin. Cell Biol
, vol.14
, pp. 286-298
-
-
Lachner, M.1
Jenuwein, T.2
-
23
-
-
34948889415
-
The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR
-
Lee, J., A. Kumagai, and W. G. Dunphy. 2007. The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR. J. Biol. Chem. 282:28036-28044.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 28036-28044
-
-
Lee, J.1
Kumagai, A.2
Dunphy, W.G.3
-
24
-
-
4544281398
-
Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins
-
Lisby, M., J. H. Barlow, R. C. Burgess, and R. Rothstein. 2004. Choreography of the DNA damage response: spatiotemporal relationships among checkpoint and repair proteins. Cell 118:699-713.
-
(2004)
Cell
, vol.118
, pp. 699-713
-
-
Lisby, M.1
Barlow, J.H.2
Burgess, R.C.3
Rothstein, R.4
-
25
-
-
0032189222
-
DNA damage checkpoint in budding yeast
-
Longhese, M. P., M. Foiani, M. Muzi-Falconi, G. Lucchini, and P. Plevani. 1998. DNA damage checkpoint in budding yeast. EMBO J. 17:5525-5528.
-
(1998)
EMBO J
, vol.17
, pp. 5525-5528
-
-
Longhese, M.P.1
Foiani, M.2
Muzi-Falconi, M.3
Lucchini, G.4
Plevani, P.5
-
26
-
-
0030804309
-
The novel DNA damage checkpoint protein Ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast
-
Longhese, M. P., V. Paciotti, R. Fraschini, R. Zaccarini, P. Plevani, and G. Lucchini. 1997. The novel DNA damage checkpoint protein Ddc1p is phosphorylated periodically during the cell cycle and in response to DNA damage in budding yeast. EMBO J. 16:5216-5226.
-
(1997)
EMBO J
, vol.16
, pp. 5216-5226
-
-
Longhese, M.P.1
Paciotti, V.2
Fraschini, R.3
Zaccarini, R.4
Plevani, P.5
Lucchini, G.6
-
27
-
-
0031820288
-
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
-
Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae. Yeast 14:953-961.
-
(1998)
Yeast
, vol.14
, pp. 953-961
-
-
Longtine, M.S.1
McKenzie III, A.2
Demarini, D.J.3
Shah, N.G.4
Wach, A.5
Brachat, A.6
Philippsen, P.7
Pringle, J.R.8
-
28
-
-
0037418195
-
Yeast Rad17/Mec3/Ddc1: A sliding clamp for the DNA damage checkpoint
-
Majka, J., and P. M. Burgers. 2003. Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc. Natl. Acad. Sci. USA 100:2249-2254.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2249-2254
-
-
Majka, J.1
Burgers, P.M.2
-
29
-
-
7744243520
-
The DNA damage response: Sensing and signaling
-
McGowan, C. H., and P. Russell. 2004. The DNA damage response: sensing and signaling. Curr. Opin. Cell Biol. 16:629-633.
-
(2004)
Curr. Opin. Cell Biol
, vol.16
, pp. 629-633
-
-
McGowan, C.H.1
Russell, P.2
-
30
-
-
0036531901
-
A unified view of the DNA-damage checkpoint
-
Melo, J., and D. Toczyski. 2002. A unified view of the DNA-damage checkpoint. Curr. Opin. Cell Biol. 14:237-245.
-
(2002)
Curr. Opin. Cell Biol
, vol.14
, pp. 237-245
-
-
Melo, J.1
Toczyski, D.2
-
32
-
-
33746234714
-
Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair
-
Ogiwara, H., A. Ui, F. Onoda, S. Tada, T. Enomoto, and M. Seki. 2006. Dpb11, the budding yeast homolog of TopBP1, functions with the checkpoint clamp in recombination repair. Nucleic Acids Res. 34:3389-3398.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 3389-3398
-
-
Ogiwara, H.1
Ui, A.2
Onoda, F.3
Tada, S.4
Enomoto, T.5
Seki, M.6
-
33
-
-
0034663809
-
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast
-
Paciotti, V., M. Clerici, G. Lucchini, and M. P. Longhese. 2000. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. Genes Dev. 14:2046-2059.
-
(2000)
Genes Dev
, vol.14
, pp. 2046-2059
-
-
Paciotti, V.1
Clerici, M.2
Lucchini, G.3
Longhese, M.P.4
-
34
-
-
0032527776
-
Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p
-
Paciotti, V., G. Lucchini, P. Plevani, and M. P. Longhese. 1998. Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p. EMBO J. 17:4199-4209.
-
(1998)
EMBO J
, vol.17
, pp. 4199-4209
-
-
Paciotti, V.1
Lucchini, G.2
Plevani, P.3
Longhese, M.P.4
-
35
-
-
0242413125
-
Cut5 is required for the binding of Atr and DNA polymerase α to genotoxin-damaged chromatin
-
Parrilla-Castellar, E. R., and L. M. Karnitz. 2003. Cut5 is required for the binding of Atr and DNA polymerase α to genotoxin-damaged chromatin. J. Biol. Chem. 278:45507-45511.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 45507-45511
-
-
Parrilla-Castellar, E.R.1
Karnitz, L.M.2
-
36
-
-
0033570894
-
Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
-
Pellicioli, A., C. Lucca, G. Liberi, F. Marini, M. Lopes, P. Plevani, A. Romano, P. P. Di Fiore, and M. Foiani. 1999. Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. EMBO J. 18:6561-6572.
-
(1999)
EMBO J
, vol.18
, pp. 6561-6572
-
-
Pellicioli, A.1
Lucca, C.2
Liberi, G.3
Marini, F.4
Lopes, M.5
Plevani, P.6
Romano, A.7
Di Fiore, P.P.8
Foiani, M.9
-
37
-
-
0034329474
-
LCD1: An essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae
-
Rouse, J., and S. P. Jackson. 2000. LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae. EMBO J. 19:5801-5812.
-
(2000)
EMBO J
, vol.19
, pp. 5801-5812
-
-
Rouse, J.1
Jackson, S.P.2
-
38
-
-
0036241880
-
Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo
-
Rouse, J., and S. P. Jackson. 2002. Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo. Mol. Cell 9:857-869.
-
(2002)
Mol. Cell
, vol.9
, pp. 857-869
-
-
Rouse, J.1
Jackson, S.P.2
-
39
-
-
8844248619
-
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage
-
Sanders, S. L., M. Portoso, J. Mata, J. Bahler, R. C. Allshire, and T. Kouzarides. 2004. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 119:603-614.
-
(2004)
Cell
, vol.119
, pp. 603-614
-
-
Sanders, S.L.1
Portoso, M.2
Mata, J.3
Bahler, J.4
Allshire, R.C.5
Kouzarides, T.6
-
40
-
-
0036281710
-
Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint
-
Schwartz, M. F., J. K. Duong, Z. Sun, J. S. Morrow, D. Pradhan, and D. F. Stern. 2002. Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. Mol. Cell 9:1055-1065.
-
(2002)
Mol. Cell
, vol.9
, pp. 1055-1065
-
-
Schwartz, M.F.1
Duong, J.K.2
Sun, Z.3
Morrow, J.S.4
Pradhan, D.5
Stern, D.F.6
-
41
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh, Y. 2003. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3:155-168.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
42
-
-
33745823159
-
The ATM-mediated DNA-damage response: Taking shape
-
Shiloh, Y. 2006. The ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 31:402-410.
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 402-410
-
-
Shiloh, Y.1
-
43
-
-
0032504069
-
Rad53 Fha domain associated with phosphorylated Rad9 in the DNA damage checkpoint
-
Sun, Z. X., J. Hsiao, D. S. Fay, and D. F. Stern. 1998. Rad53 Fha domain associated with phosphorylated Rad9 in the DNA damage checkpoint. Science 281:272-274.
-
(1998)
Science
, vol.281
, pp. 272-274
-
-
Sun, Z.X.1
Hsiao, J.2
Fay, D.S.3
Stern, D.F.4
-
45
-
-
33746597380
-
Rad4TopBP1, a scaffold protein, plays separate roles in DNA damage and replication checkpoints and DNA replication
-
Taricani, L., and T. S. Wang. 2006. Rad4TopBP1, a scaffold protein, plays separate roles in DNA damage and replication checkpoints and DNA replication. Mol. Biol. Cell 17:3456-3468.
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 3456-3468
-
-
Taricani, L.1
Wang, T.S.2
-
46
-
-
33646777111
-
Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation
-
Toh, G. W., A. M. O'Shaughnessy, S. Jimeno, I. M. Dobbie, M. Grenon, S. Maffini, A. O'Rorke, and N. F. Lowndes. 2006. Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation. DNA Repair 5:693-703.
-
(2006)
DNA Repair
, vol.5
, pp. 693-703
-
-
Toh, G.W.1
O'Shaughnessy, A.M.2
Jimeno, S.3
Dobbie, I.M.4
Grenon, M.5
Maffini, S.6
O'Rorke, A.7
Lowndes, N.F.8
-
47
-
-
0036237806
-
Genetic and physical interactions between DPB11 and DDC1 in the yeast DNA damage response pathway
-
Wang, H., and S. J. Elledge. 2002. Genetic and physical interactions between DPB11 and DDC1 in the yeast DNA damage response pathway. Genetics 160:1295-1304.
-
(2002)
Genetics
, vol.160
, pp. 1295-1304
-
-
Wang, H.1
Elledge, S.J.2
-
49
-
-
33846328709
-
Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast
-
Zegerman, P., and J. F. X. Diffley. 2007. Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast. Nature 445:281-285.
-
(2007)
Nature
, vol.445
, pp. 281-285
-
-
Zegerman, P.1
Diffley, J.F.X.2
-
50
-
-
0141483484
-
Identification of novel histone posttranslational modifications by peptide mass fingerprinting
-
Zhang, L., E. E. Eugeni, M. R. Parthun, and M. A. Freitas. 2003. Identification of novel histone posttranslational modifications by peptide mass fingerprinting. Chromosoma 112:77-86.
-
(2003)
Chromosoma
, vol.112
, pp. 77-86
-
-
Zhang, L.1
Eugeni, E.E.2
Parthun, M.R.3
Freitas, M.A.4
-
51
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou, L., and S. J. Elledge. 2003. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300:1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
|