Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages

PLoS Pathogens

Volumn 7, Issue 6, 2011, Pages

  Daniel, Jaiyanth ^a   Maamar, Hédia ^a   Deb, Chirajyoti ^a   Sirakova, Tatiana D ^a   Kolattukudy, Pappachan E ^a  

^a UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAT DROPLET; FATTY ACID; ISONIAZID; TRIACYLGLYCEROL; TRIACYLGLYCEROL SYNTHASE 1; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; CELL CULTURE; DORMANCY; GENE DELETION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; HYPOXIA; INTRACELLULAR BACTERIUM; ISOTOPE LABELING; LIPID METABOLISM; LIPID STORAGE; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; PATHOGENESIS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; ANOXIA; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PATHOGENICITY; UPREGULATION;

MYCOBACTERIUM TUBERCULOSIS;

ANOXIA; CELLS, CULTURED; GENES, BACTERIAL; HOST-PATHOGEN INTERACTIONS; HUMANS; LIPID METABOLISM; MACROPHAGES; MYCOBACTERIUM TUBERCULOSIS; TRIGLYCERIDES; UP-REGULATION;

EID: 79959815079     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002093     Document Type: Article

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