-
2
-
-
0017075792
-
The granulomatous inflammatory response: A review
-
Adams DO (1976) The granulomatous inflammatory response: a review. Am J Pathol 84:164-192
-
(1976)
Am J Pathol
, vol.84
, pp. 164-192
-
-
Adams, D.O.1
-
3
-
-
0014634514
-
The granulomatous inflammatory exudate
-
Spector WG (1969) The granulomatous inflammatory exudate. Int Rev Exp Pathol 8:1-55
-
(1969)
Int Rev Exp Pathol
, vol.8
, pp. 1-55
-
-
Spector, W.G.1
-
5
-
-
0016253236
-
The structure of mononuclear phagocytes differentiating in vivo i Sequential fine and histologic studies of the effect of Bacillus Calmette-Guerin (BCG)
-
Adams DO (1974) The structure of mononuclear phagocytes differentiating in vivo I Sequential fine and histologic studies of the effect of Bacillus Calmette-Guerin (BCG). Am J Pathol 76:17-48
-
(1974)
Am J Pathol
, vol.76
, pp. 17-48
-
-
Adams, D.O.1
-
6
-
-
0014376491
-
The structure and function of monocytes and macrophages
-
Cohn ZA (1968) The structure and function of monocytes and macrophages. Adv Immunol 9:163-214
-
(1968)
Adv Immunol
, vol.9
, pp. 163-214
-
-
Cohn, Z.A.1
-
7
-
-
0014291846
-
Cellular hypersensitivity and cellular immunity in the pathogensis of Tuberculosis: Specificity, systemic and local nature, and associated macrophage enzymes
-
Dannenberg AM Jr (1968) Cellular hypersensitivity and cellular immunity in the pathogensis of Tuberculosis: specificity, systemic and local nature, and associated macrophage enzymes. Bacteriol Rev 32:85-102
-
(1968)
Bacteriol Rev
, vol.32
, pp. 85-102
-
-
Dannenberg, Jr.A.M.1
-
8
-
-
0035179747
-
Dynamic nature of host-pathogen interactions in Mycobacterium marinum granulomas
-
Bouley DM et al (2001) Dynamic nature of host-pathogen interactions in Mycobacterium marinum granulomas. Infect Immun 69:7820-7831
-
(2001)
Infect Immun
, vol.69
, pp. 7820-7831
-
-
Bouley, D.M.1
-
10
-
-
80755128440
-
Pathology of post primary Tuberculosis of the lung: An illustrated critical review
-
Hunter RL (2011) Pathology of post primary Tuberculosis of the lung: an illustrated critical review. Tuberculosis 91:497-509
-
(2011)
Tuberculosis
, vol.91
, pp. 497-509
-
-
Hunter, R.L.1
-
13
-
-
84860247190
-
Revisiting the role of the granuloma in Tuberculosis
-
Ramakrishnan L (2012) Revisiting the role of the granuloma in Tuberculosis. Nat Rev Immunol 12:352-366
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 352-366
-
-
Ramakrishnan, L.1
-
14
-
-
0027471981
-
Immunopathogenesis of pulmonary Tuberculosis
-
Dannenberg AMJ (1993) Immunopathogenesis of pulmonary Tuberculosis. Hosp Pract 28:51-58
-
(1993)
Hosp Pract
, vol.28
, pp. 51-58
-
-
Dannenberg, A.M.J.1
-
15
-
-
34848910546
-
Mycobacterium Tuberculosis infects dendritic cells with high frequency and impairs their function in vivo
-
Wolf AJ et al (2007) Mycobacterium Tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. J Immunol 179:2509-2519
-
(2007)
J Immunol
, vol.179
, pp. 2509-2519
-
-
Wolf, A.J.1
-
17
-
-
0000305402
-
The reisdual infectivity of the primary complex of Tuberculosis
-
Feldman WH, Baggenstoss AH (1938) The reisdual infectivity of the primary complex of Tuberculosis. Am J Pathol 14:473-490
-
(1938)
Am J Pathol
, vol.14
, pp. 473-490
-
-
Feldman, W.H.1
Baggenstoss, A.H.2
-
18
-
-
0001776002
-
Tubercle bacilli in latent tuberculous lesions and in lung tissue without tuberculous lesions
-
Opie EL, Aronson JD (1927) Tubercle bacilli in latent tuberculous lesions and in lung tissue without tuberculous lesions. Arch Pathol Lab Med 4:1-21
-
(1927)
Arch Pathol Lab Med
, vol.4
, pp. 1-21
-
-
Opie, E.L.1
Aronson, J.D.2
-
19
-
-
0035064072
-
Immunology of Tuberculosis
-
Flynn JL, Chan J (2001) Immunology of Tuberculosis. Annu Rev Immunol 19:93-129
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 93-129
-
-
Flynn, J.L.1
Chan, J.2
-
20
-
-
0033826580
-
Is the development of a new Tuberculosis vaccine possible?
-
Kaufmann SH (2000) Is the development of a new Tuberculosis vaccine possible? Nat Med 6:955-960
-
(2000)
Nat Med
, vol.6
, pp. 955-960
-
-
Kaufmann, S.H.1
-
21
-
-
0036274370
-
Tuberculosis unleashed: The impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium Tuberculosis
-
Lawn SD, Butera ST, Shinnick TM (2002) Tuberculosis unleashed: the impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium Tuberculosis. Microbes Infect 4:635-646
-
(2002)
Microbes Infect
, vol.4
, pp. 635-646
-
-
Lawn, S.D.1
Butera, S.T.2
Shinnick, T.M.3
-
22
-
-
0027771385
-
Granuloma formation in severe combined immunodeficient (SCID) mice in response to progressive BCG infection tendency not to form granulomas in the lung is associated with faster bacterial growth in this organ
-
North RJ, Izzo AA (1993) Granuloma formation in severe combined immunodeficient (SCID) mice in response to progressive BCG infection tendency not to form granulomas in the lung is associated with faster bacterial growth in this organ. Am J Pathol 142:1959-1966
-
(1993)
Am J Pathol
, vol.142
, pp. 1959-1966
-
-
North, R.J.1
Izzo, A.A.2
-
23
-
-
0027482327
-
Disseminated Tuberculosis in interferon gamma gene-disrupted mice
-
Cooper AM et al (1993) Disseminated Tuberculosis in interferon gamma gene-disrupted mice. J Exp Med 178:2243-2247
-
(1993)
J Exp Med
, vol.178
, pp. 2243-2247
-
-
Cooper, A.M.1
-
24
-
-
0030790652
-
Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium Tuberculosis
-
Cooper AM et al (1997) Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium Tuberculosis. J Exp Med 186:39-45
-
(1997)
J Exp Med
, vol.186
, pp. 39-45
-
-
Cooper, A.M.1
-
25
-
-
0027360333
-
An essential role for interferon gamma in resistance to Mycobacterium Tuberculosis infection
-
Flynn JL et al (1993) An essential role for interferon gamma in resistance to Mycobacterium Tuberculosis infection. J Exp Med 178:2249-2254
-
(1993)
J Exp Med
, vol.178
, pp. 2249-2254
-
-
Flynn, J.L.1
-
26
-
-
34548704962
-
IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium Tuberculosis infection
-
Fremond CM et al (2007) IL-1 receptor-mediated signal is an essential component of MyD88-dependent innate response to Mycobacterium Tuberculosis infection. J Immunol 179:1178-1189
-
(2007)
J Immunol
, vol.179
, pp. 1178-1189
-
-
Fremond, C.M.1
-
27
-
-
14044253038
-
Fatal Mycobacterium Tuberculosis infection despite adaptive immune response in the absence of MyD88
-
Fremond CM et al (2004) Fatal Mycobacterium Tuberculosis infection despite adaptive immune response in the absence of MyD88. J Clin Invest 114:1790-1799
-
(2004)
J Clin Invest
, vol.114
, pp. 1790-1799
-
-
Fremond, C.M.1
-
28
-
-
0033823682
-
Interleukin-1 signaling is essential for host defense during murine pulmonary Tuberculosis
-
Juffermans N et al (2000) Interleukin-1 signaling is essential for host defense during murine pulmonary Tuberculosis. J Infect Dis 182:902-908
-
(2000)
J Infect Dis
, vol.182
, pp. 902-908
-
-
Juffermans, N.1
-
29
-
-
1842588021
-
MyD88-deficient mice display a profound loss in resistance to Mycobacterium Tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression
-
Scanga CA et al (2004) MyD88-deficient mice display a profound loss in resistance to Mycobacterium Tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression. Infect Immun 72:2400-2404
-
(2004)
Infect Immun
, vol.72
, pp. 2400-2404
-
-
Scanga, C.A.1
-
30
-
-
0037241835
-
Relative importance of STAT4 in murine Tuberculosis
-
Sugawara I, Yamada H, Mizuno S (2003) Relative importance of STAT4 in murine Tuberculosis. J Med Microbiol 52:29-34
-
(2003)
J Med Microbiol
, vol.52
, pp. 29-34
-
-
Sugawara, I.1
Yamada, H.2
Mizuno, S.3
-
31
-
-
22544467821
-
Tumor necrosis factor and chemokine interactions in the formation and maintenance of granulomas in Tuberculosis
-
Algood HM, Lin L, Flynn JL (2005) Tumor necrosis factor and chemokine interactions in the formation and maintenance of granulomas in Tuberculosis. Clin Infect Dis 41:S189-S193
-
(2005)
Clin Infect Dis
, vol.41
-
-
Algood, H.M.1
Lin, L.2
Flynn, J.L.3
-
32
-
-
0033559125
-
Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium Tuberculosis infection, which is not compensated for by lymphotoxin
-
Bean AG et al (1999) Structural deficiencies in granuloma formation in TNF gene-targeted mice underlie the heightened susceptibility to aerosol Mycobacterium Tuberculosis infection, which is not compensated for by lymphotoxin. J Immunol 162:3504-3511
-
(1999)
J Immunol
, vol.162
, pp. 3504-3511
-
-
Bean, A.G.1
-
33
-
-
40749108974
-
Tumor necrosis factor blockade in chronic murine Tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs
-
Chakravarty SD et al (2008) Tumor necrosis factor blockade in chronic murine Tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs. Infect Immun 76:916-926
-
(2008)
Infect Immun
, vol.76
, pp. 916-926
-
-
Chakravarty, S.D.1
-
34
-
-
0028979703
-
Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium Tuberculosis in mice
-
Flynn JL et al (1995) Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium Tuberculosis in mice. Immunity 2:561-572
-
(1995)
Immunity
, vol.2
, pp. 561-572
-
-
Flynn, J.L.1
-
35
-
-
0024566140
-
The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection
-
Kindler V et al (1989) The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell 56:731-740
-
(1989)
Cell
, vol.56
, pp. 731-740
-
-
Kindler, V.1
-
36
-
-
0036569910
-
TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection
-
Roach DR et al (2002) TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection. J Immunol 168:4620-4627
-
(2002)
J Immunol
, vol.168
, pp. 4620-4627
-
-
Roach, D.R.1
-
37
-
-
27444432605
-
Immunological control of Tuberculosis: Role of tumour necrosis factor and more
-
Stenger S (2005) Immunological control of Tuberculosis: role of tumour necrosis factor and more. Ann Rheum Dis 64:iv24-iv28
-
(2005)
Ann Rheum Dis
, vol.64
-
-
Stenger, S.1
-
38
-
-
48749114458
-
Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death
-
Clay H, Volkman HE, Ramakrishnan L (2008) Tumor necrosis factor signaling mediates resistance to mycobacteria by inhibiting bacterial growth and macrophage death. Immunity 29:283-294
-
(2008)
Immunity
, vol.29
, pp. 283-294
-
-
Clay, H.1
Volkman, H.E.2
Ramakrishnan, L.3
-
39
-
-
66649092620
-
The granuloma in Tuberculosis-friend or foe?
-
Rubin EJ (2009) The granuloma in Tuberculosis-friend or foe? N Engl J Med 360:2471-2473
-
(2009)
N Engl J Med
, vol.360
, pp. 2471-2473
-
-
Rubin, E.J.1
-
40
-
-
58149089157
-
Who benefits from granulomas, mycobacteria or host?
-
Bold TD, Ernst JD (2009) Who benefits from granulomas, mycobacteria or host? Cell 136:17-19
-
(2009)
Cell
, vol.136
, pp. 17-19
-
-
Bold, T.D.1
Ernst, J.D.2
-
41
-
-
31144446585
-
New insights into the function of granulomas in human Tuberculosis
-
Ulrichs T, Kaufmann SH (2006) New insights into the function of granulomas in human Tuberculosis. J Pathol 208:261-269
-
(2006)
J Pathol
, vol.208
, pp. 261-269
-
-
Ulrichs, T.1
Kaufmann, S.H.2
-
43
-
-
0003955573
-
-
7th edn. Churchill Livingston, Philadelphia
-
Mandell GL, Bennett JE, Dolin R (eds) (2010) Mandell, Douglas, and Bennett's principles and practice of infectious diseases, 7th edn. Churchill Livingston, Philadelphia
-
(2010)
Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases
-
-
Mandell, G.L.1
Bennett, J.E.2
Dolin, R.3
-
46
-
-
42149094416
-
Comparative pathogenesis of Mycobacterium marinum and Mycobacterium Tuberculosis
-
Tobin DM, Ramakrishnan L (2008) Comparative pathogenesis of Mycobacterium marinum and Mycobacterium Tuberculosis. Cell Microbiol 10:1027-1039
-
(2008)
Cell Microbiol
, vol.10
, pp. 1027-1039
-
-
Tobin, D.M.1
Ramakrishnan, L.2
-
47
-
-
0030743238
-
Images in clinical medicine Mycobacterium marinum infection of the hand
-
Ramakrishnan L (1997) Images in clinical medicine Mycobacterium marinum infection of the hand. N Engl J Med 337:612
-
(1997)
N Engl J Med
, vol.337
, pp. 612
-
-
Ramakrishnan, L.1
-
48
-
-
0031018261
-
Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens)
-
Ramakrishnan L et al (1997) Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens). Infect Immun 65:767-773
-
(1997)
Infect Immun
, vol.65
, pp. 767-773
-
-
Ramakrishnan, L.1
-
49
-
-
33750439462
-
Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous Tuberculosis and is moderated by adaptive immunity
-
Swaim LE et al (2006) Mycobacterium marinum infection of adult zebrafish causes caseating granulomatous Tuberculosis and is moderated by adaptive immunity. Infect Immun 74:6108-6117
-
(2006)
Infect Immun
, vol.74
, pp. 6108-6117
-
-
Swaim, L.E.1
-
50
-
-
84856693171
-
Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections
-
Tobin DM et al (2012) Host genotype-specific therapies can optimize the inflammatory response to mycobacterial infections. Cell 148:434-446
-
(2012)
Cell
, vol.148
, pp. 434-446
-
-
Tobin, D.M.1
-
51
-
-
77649128120
-
The lta4 h locus modulates susceptibility to mycobacterial infection in zebrafish and humans
-
Tobin DM et al (2010) The lta4 h locus modulates susceptibility to mycobacterial infection in zebrafish and humans. Cell 140:717-730
-
(2010)
Cell
, vol.140
, pp. 717-730
-
-
Tobin, D.M.1
-
52
-
-
0036403086
-
CD4 is required for the development of a protective granulomatous response to pulmonary Tuberculosis
-
Saunders BM et al (2002) CD4 is required for the development of a protective granulomatous response to pulmonary Tuberculosis. Cell Immunol 216:65-72
-
(2002)
Cell Immunol
, vol.216
, pp. 65-72
-
-
Saunders, B.M.1
-
53
-
-
0344289512
-
Exogenous reinfection as a cause of recurrent Tuberculosis after curative treatment
-
van Rie A et al (1999) Exogenous reinfection as a cause of recurrent Tuberculosis after curative treatment. N Engl J Med 341:1174-1179
-
(1999)
N Engl J Med
, vol.341
, pp. 1174-1179
-
-
Van Rie, A.1
-
54
-
-
20444401506
-
Rate of reinfection Tuberculosis after successful treatment is higher than rate of new Tuberculosis
-
Verver S et al (2005) Rate of reinfection Tuberculosis after successful treatment is higher than rate of new Tuberculosis. Am J Respir Crit Care Med 171:1430-1435
-
(2005)
Am J Respir Crit Care Med
, vol.171
, pp. 1430-1435
-
-
Verver, S.1
-
55
-
-
0035087220
-
Exogenous reinfection with Tuberculosis on a European island with a moderate incidence of disease
-
Caminero JA et al (2001) Exogenous reinfection with Tuberculosis on a European island with a moderate incidence of disease. Am J Respir Crit Care Med 163:717-720
-
(2001)
Am J Respir Crit Care Med
, vol.163
, pp. 717-720
-
-
Caminero, J.A.1
-
56
-
-
0035495579
-
How can immunology contribute to the control of Tuberculosis?
-
Kaufmann SH (2001) How can immunology contribute to the control of Tuberculosis? Nat Rev Immunol 1:20-30
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 20-30
-
-
Kaufmann, S.H.1
-
57
-
-
0028241565
-
Pathogenesis of Tuberculosis: Pathway to apical localization
-
Balasubramanian V et al (1994) Pathogenesis of Tuberculosis: pathway to apical localization. Tuber Lung Dis 75:168-178
-
(1994)
Tuber Lung Dis
, vol.75
, pp. 168-178
-
-
Balasubramanian, V.1
-
58
-
-
0034502343
-
Persistence of DNA from Mycobacterium Tuberculosis in superficially normal lung tissue during latent infection
-
Hernandez-Pando R et al (2000) Persistence of DNA from Mycobacterium Tuberculosis in superficially normal lung tissue during latent infection. Lancet 356:2133-2138
-
(2000)
Lancet
, vol.356
, pp. 2133-2138
-
-
Hernandez-Pando, R.1
-
59
-
-
0038520776
-
Hematogenous reseeding of the lung in low-dose, aerosol-infected guinea pigs: Unique features of the host-pathogen interface in secondary tubercles
-
McMurray DN (2003) Hematogenous reseeding of the lung in low-dose, aerosol-infected guinea pigs: unique features of the host-pathogen interface in secondary tubercles. Tuberculosis 83:131-134
-
(2003)
Tuberculosis
, vol.83
, pp. 131-134
-
-
McMurray, D.N.1
-
60
-
-
0037417012
-
Mycobacterium Tuberculosis in the extracellular compartment: An underestimated adversary
-
Grosset J (2003) Mycobacterium Tuberculosis in the extracellular compartment: an underestimated adversary. Antimicrob Agents Chemother 47:833-836
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 833-836
-
-
Grosset, J.1
-
61
-
-
4444264777
-
Superinfecting mycobacteria home to established tuberculous granulomas
-
Cosma CL, Humbert O, Ramakrishnan L (2004) Superinfecting mycobacteria home to established tuberculous granulomas. Nat Immunol 5:828-835
-
(2004)
Nat Immunol
, vol.5
, pp. 828-835
-
-
Cosma, C.L.1
Humbert, O.2
Ramakrishnan, L.3
-
62
-
-
56749148643
-
Trafficking of superinfecting Mycobacterium organisms into established granulomas occurs in mammals and is independent of the Erp and ESX-1 mycobacterial virulence loci
-
Cosma CL et al (2008) Trafficking of superinfecting Mycobacterium organisms into established granulomas occurs in mammals and is independent of the Erp and ESX-1 mycobacterial virulence loci. J Infect Dis 198:1851-1855
-
(2008)
J Infect Dis
, vol.198
, pp. 1851-1855
-
-
Cosma, C.L.1
-
63
-
-
0037133580
-
Complex pattern of Mycobacterium marinum gene expression during long-term granulomatous infection
-
Chan K et al (2002) Complex pattern of Mycobacterium marinum gene expression during long-term granulomatous infection. Proc Natl Acad Sci U S A 99:3920-3925
-
(2002)
Proc Natl Acad Sci U S a
, vol.99
, pp. 3920-3925
-
-
Chan, K.1
-
64
-
-
0034717008
-
Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE- PGRS family
-
Ramakrishnan L, Federspiel NA, Falkow S (2000) Granuloma-specific expression of Mycobacterium virulence proteins from the glycine-rich PE- PGRS family. Science 288:1436-1439
-
(2000)
Science
, vol.288
, pp. 1436-1439
-
-
Ramakrishnan, L.1
Federspiel, N.A.2
Falkow, S.3
-
65
-
-
67650932256
-
Cell-mediated immune responses in Tuberculosis
-
Cooper AM (2009) Cell-mediated immune responses in Tuberculosis. Annu Rev Immunol 27:393-422
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 393-422
-
-
Cooper, A.M.1
-
66
-
-
53349118087
-
Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M Tuberculosis infection
-
Gallegos AM, Pamer EG, Glickman MS (2008) Delayed protection by ESAT-6-specific effector CD4+ T cells after airborne M Tuberculosis infection. J Exp Med 205:2359-2368
-
(2008)
J Exp Med
, vol.205
, pp. 2359-2368
-
-
Gallegos, A.M.1
Pamer, E.G.2
Glickman, M.S.3
-
67
-
-
59649119960
-
A replication clock for Mycobacterium Tuberculosis
-
Gill W et al (2009) A replication clock for Mycobacterium Tuberculosis. Nature Med 15:211-214
-
(2009)
Nature Med
, vol.15
, pp. 211-214
-
-
Gill, W.1
-
68
-
-
38749138163
-
Initiation of the adaptive immune response to Mycobacterium Tuberculosis depends on antigen production in the local lymph node, not the lungs
-
Wolf AJ et al (2008) Initiation of the adaptive immune response to Mycobacterium Tuberculosis depends on antigen production in the local lymph node, not the lungs. J Exp Med 205:105-115
-
(2008)
J Exp Med
, vol.205
, pp. 105-115
-
-
Wolf, A.J.1
-
70
-
-
0031034737
-
Host responses and antigens involved in protective immunity to Mycobacterium Tuberculosis
-
Andersen P (1997) Host responses and antigens involved in protective immunity to Mycobacterium Tuberculosis. Scand J Immunol 45:115-131
-
(1997)
Scand J Immunol
, vol.45
, pp. 115-131
-
-
Andersen, P.1
-
71
-
-
0033846833
-
Restraining mycobacteria: Role of granulomas in mycobacterial infections
-
Saunders BM, Cooper AM (2000) Restraining mycobacteria: role of granulomas in mycobacterial infections. Immunol Cell Biol 78:334-341
-
(2000)
Immunol Cell Biol
, vol.78
, pp. 334-341
-
-
Saunders, B.M.1
Cooper, A.M.2
-
72
-
-
18744363879
-
Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos
-
Davis JM et al (2002) Real-time visualization of mycobacterium-macrophage interactions leading to initiation of granuloma formation in zebrafish embryos. Immunity 17:693-702
-
(2002)
Immunity
, vol.17
, pp. 693-702
-
-
Davis, J.M.1
-
73
-
-
14044254749
-
Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
-
Volkman HE et al (2004) Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant. PLoS Biol 2:e367
-
(2004)
PLoS Biol
, vol.2
-
-
Volkman, H.E.1
-
74
-
-
58149083837
-
The role of the granuloma in expansion and dissemination of early tuberculous infection
-
Davis JM, Ramakrishnan L (2009) The role of the granuloma in expansion and dissemination of early tuberculous infection. Cell 136:37-49
-
(2009)
Cell
, vol.136
, pp. 37-49
-
-
Davis, J.M.1
Ramakrishnan, L.2
-
75
-
-
38949096968
-
Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas
-
Egen JG et al (2008) Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas. Immunity 28:271-284
-
(2008)
Immunity
, vol.28
, pp. 271-284
-
-
Egen, J.G.1
-
76
-
-
79956302280
-
Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas
-
Egen JG et al (2011) Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas. Immunity 34:807-819
-
(2011)
Immunity
, vol.34
, pp. 807-819
-
-
Egen, J.G.1
-
77
-
-
3042803777
-
Mycobacterium Tuberculosis H37Rv: Delta RD1 is more virulent than M bovis bacille Calmette-Guerin in long-term murine infection
-
Sherman DR et al (2004) Mycobacterium Tuberculosis H37Rv: Delta RD1 is more virulent than M bovis bacille Calmette-Guerin in long-term murine infection. J Infect Dis 190:123-126
-
(2004)
J Infect Dis
, vol.190
, pp. 123-126
-
-
Sherman, D.R.1
-
78
-
-
4644320227
-
A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion
-
Gao LY et al (2004) A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion. Mol Microbiol 53:1677-1693
-
(2004)
Mol Microbiol
, vol.53
, pp. 1677-1693
-
-
Gao, L.Y.1
-
79
-
-
0942290453
-
Individual RD1-region genes are required for export of ESAT-6/ CFP-10 and for virulence of Mycobacterium Tuberculosis
-
Guinn KM et al (2004) Individual RD1-region genes are required for export of ESAT-6/ CFP-10 and for virulence of Mycobacterium Tuberculosis. Mol Microbiol 51:359-370
-
(2004)
Mol Microbiol
, vol.51
, pp. 359-370
-
-
Guinn, K.M.1
-
80
-
-
77952956465
-
Endoplasmic reticulum stress response is involved in Mycobacterium Tuberculosis protein ESAT-6-mediated apoptosis
-
Choi HH et al (2010) Endoplasmic reticulum stress response is involved in Mycobacterium Tuberculosis protein ESAT-6-mediated apoptosis. FEBS Lett 584:2445-2454
-
(2010)
FEBS Lett
, vol.584
, pp. 2445-2454
-
-
Choi, H.H.1
-
81
-
-
34248671986
-
The ESAT-6 protein of Mycobacterium Tuberculosis induces apoptosis of macrophages by activating caspase expression
-
Derrick SC, Morris SL (2007) The ESAT-6 protein of Mycobacterium Tuberculosis induces apoptosis of macrophages by activating caspase expression. Cell Microbiol 9:1547-1555
-
(2007)
Cell Microbiol
, vol.9
, pp. 1547-1555
-
-
Derrick, S.C.1
Morris, S.L.2
-
82
-
-
77957133396
-
Mycobacterium Tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome
-
Mishra BB et al (2010) Mycobacterium Tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome. Cell Microbiol 12:1046-1063
-
(2010)
Cell Microbiol
, vol.12
, pp. 1046-1063
-
-
Mishra, B.B.1
-
83
-
-
79955082538
-
Apoptosis is an innate defense function of macrophages against Mycobacterium Tuberculosis
-
Behar SM et al (2011) Apoptosis is an innate defense function of macrophages against Mycobacterium Tuberculosis. Mucosal Immunol 4:279-287
-
(2011)
Mucosal Immunol
, vol.4
, pp. 279-287
-
-
Behar, S.M.1
-
84
-
-
0031133280
-
Programmed cell death of Mycobacterium avium serovar 4-infected human macrophages prevents the mycobacteria from spreading and induces mycobacterial growth inhibition by freshly added, uninfected macrophages
-
Fratazzi C et al (1997) Programmed cell death of Mycobacterium avium serovar 4-infected human macrophages prevents the mycobacteria from spreading and induces mycobacterial growth inhibition by freshly added, uninfected macrophages. J Immunol 158:4320-4327
-
(1997)
J Immunol
, vol.158
, pp. 4320-4327
-
-
Fratazzi, C.1
-
85
-
-
52549123569
-
Mycobacterium Tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence
-
Gan H et al (2008) Mycobacterium Tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence. Nat Immunol 9:1189-1197
-
(2008)
Nat Immunol
, vol.9
, pp. 1189-1197
-
-
Gan, H.1
-
86
-
-
0036395920
-
TNF-dependent BALB/c murine macrophage apoptosis following Mycobacterium Tuberculosis infection inhibits bacillary growth in an IFN-gamma independent manner
-
Keane J, Shurtleff B, Kornfeld H (2002) TNF-dependent BALB/c murine macrophage apoptosis following Mycobacterium Tuberculosis infection inhibits bacillary growth in an IFN-gamma independent manner. Tuberculosis 82:55-61
-
(2002)
Tuberculosis
, vol.82
, pp. 55-61
-
-
Keane, J.1
Shurtleff, B.2
Kornfeld, H.3
-
87
-
-
84866403046
-
Efferocytosis is an innate antibacterial mechanism
-
Martin CJ et al (2012) Efferocytosis is an innate antibacterial mechanism. Cell Host and Microbe 12:289-300
-
(2012)
Cell Host and Microbe
, vol.12
, pp. 289-300
-
-
Martin, C.J.1
-
88
-
-
0032103037
-
Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium Tuberculosis
-
Oddo M et al (1998) Fas ligand-induced apoptosis of infected human macrophages reduces the viability of intracellular Mycobacterium Tuberculosis. J Immunol 160:5448-5454
-
(1998)
J Immunol
, vol.160
, pp. 5448-5454
-
-
Oddo, M.1
-
89
-
-
0028136987
-
Laochumroonvorapong, and G Kaplan, Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin
-
Molloy A (1994) Laochumroonvorapong, and G Kaplan, Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin. J Exp Med 180:1499-1509
-
(1994)
J Exp Med
, vol.180
, pp. 1499-1509
-
-
Molloy, A.1
-
90
-
-
0030840444
-
ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors
-
Lammas DA et al (1997) ATP-induced killing of mycobacteria by human macrophages is mediated by purinergic P2Z(P2X7) receptors. Immunity 7:433-444
-
(1997)
Immunity
, vol.7
, pp. 433-444
-
-
Lammas, D.A.1
-
91
-
-
0016742008
-
Phagosome-lysosome interactions in cultured macrophages infected with virulent tubercle bacilli Reversal of the usual nonfusion pattern and observations on bacterial survival
-
Armstrong JA, Hart D (1975) Phagosome-lysosome interactions in cultured macrophages infected with virulent tubercle bacilli Reversal of the usual nonfusion pattern and observations on bacterial survival. J Exp Med 142:1-16
-
(1975)
J Exp Med
, vol.142
, pp. 1-16
-
-
Armstrong, J.A.1
Hart, D.2
-
93
-
-
48649102274
-
Living on the edge: Inhibition of host cell apoptosis by Mycobacterium Tuberculosis
-
Briken V, Miller JL (2008) Living on the edge: inhibition of host cell apoptosis by Mycobacterium Tuberculosis. Futur Microbiol 3:415-422
-
(2008)
Futur Microbiol
, vol.3
, pp. 415-422
-
-
Briken, V.1
Miller, J.L.2
-
94
-
-
34547614056
-
Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium Tuberculosis
-
Hinchey J et al (2007) Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium Tuberculosis. J Clin Invest 117:2279-2288
-
(2007)
J Clin Invest
, vol.117
, pp. 2279-2288
-
-
Hinchey, J.1
-
95
-
-
38049097940
-
Protein kinase e of Mycobacterium Tuberculosis has a role in the nitric oxide stress response and apoptosis in a human macrophage model of infection
-
Jayakumar D, Jacobs WR Jr, Narayanan S (2008) Protein kinase E of Mycobacterium Tuberculosis has a role in the nitric oxide stress response and apoptosis in a human macrophage model of infection. Cell Microbiol 10:365-374
-
(2008)
Cell Microbiol
, vol.10
, pp. 365-374
-
-
Jayakumar, D.1
Jacobs, Jr.W.R.2
Narayanan, S.3
-
96
-
-
34547642553
-
Mycobacterium Tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells
-
Velmurugan K et al (2007) Mycobacterium Tuberculosis nuoG is a virulence gene that inhibits apoptosis of infected host cells. PLoS Pathog 3:e110
-
(2007)
PLoS Pathog
, vol.3
-
-
Velmurugan, K.1
-
97
-
-
84866348007
-
Neutrophils protect against Tuberculosis by oxidative killing of mycobacteria phagocytosed from granuloma macrophages
-
Yang CT et al (2012) Neutrophils protect against Tuberculosis by oxidative killing of mycobacteria phagocytosed from granuloma macrophages. Cell Host Microbe 12:301-312
-
(2012)
Cell Host Microbe
, vol.12
, pp. 301-312
-
-
Yang, C.T.1
-
98
-
-
0023546916
-
Cell death in granulomata: The role of apoptosis
-
Cree IA et al (1987) Cell death in granulomata: the role of apoptosis. J Clin Pathol 40:1314-1319
-
(1987)
J Clin Pathol
, vol.40
, pp. 1314-1319
-
-
Cree, I.A.1
-
99
-
-
0031015731
-
Infection by Mycobacterium Tuberculosis promotes human alveolar macrophage apoptosis
-
Keane J et al (1997) Infection by Mycobacterium Tuberculosis promotes human alveolar macrophage apoptosis. Infect Immun 65:298-304
-
(1997)
Infect Immun
, vol.65
, pp. 298-304
-
-
Keane, J.1
-
100
-
-
0033838284
-
Apoptosis of macrophages and T cells in Tuberculosis associated caseous necrosis
-
Fayyazi A et al (2000) Apoptosis of macrophages and T cells in Tuberculosis associated caseous necrosis. J Pathol 191:417-425
-
(2000)
J Pathol
, vol.191
, pp. 417-425
-
-
Fayyazi, A.1
-
101
-
-
34347324042
-
Dichotomous role of the macrophage in early Mycobacterium marinum infection of the zebrafish
-
Clay H et al (2007) Dichotomous role of the macrophage in early Mycobacterium marinum infection of the zebrafish. Cell Host Microbe 2:29-39
-
(2007)
Cell Host Microbe
, vol.2
, pp. 29-39
-
-
Clay, H.1
-
102
-
-
58149296186
-
Lipid mediators in innate immunity against Tuberculosis: Opposing roles of PGE2 and LXA4 in the induction of macrophage death
-
Chen M et al (2008) Lipid mediators in innate immunity against Tuberculosis: opposing roles of PGE2 and LXA4 in the induction of macrophage death. J Exp Med 205:2791-2801
-
(2008)
J Exp Med
, vol.205
, pp. 2791-2801
-
-
Chen, M.1
-
103
-
-
67651171188
-
Mycobacterium Tuberculosis evades macrophage defenses by inhibiting plasma membrane repair
-
Divangahi M et al (2009) Mycobacterium Tuberculosis evades macrophage defenses by inhibiting plasma membrane repair. Nat Immunol 10:899-906
-
(2009)
Nat Immunol
, vol.10
, pp. 899-906
-
-
Divangahi, M.1
-
104
-
-
77954957267
-
Eicosanoid pathways regulate adaptive immunity to Mycobacterium Tuberculosis
-
Divangahi M et al (2010) Eicosanoid pathways regulate adaptive immunity to Mycobacterium Tuberculosis. Nat Immunol 11:751-758
-
(2010)
Nat Immunol
, vol.11
, pp. 751-758
-
-
Divangahi, M.1
-
105
-
-
75649141266
-
Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium
-
Volkman HE et al (2010) Tuberculous granuloma induction via interaction of a bacterial secreted protein with host epithelium. Science 327:466-469
-
(2010)
Science
, vol.327
, pp. 466-469
-
-
Volkman, H.E.1
-
106
-
-
0038059516
-
Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9)
-
Van den Steen E et al (2002) Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9). Crit Rev Biochem Mol Biol 37:375-536
-
(2002)
Crit Rev Biochem Mol Biol
, vol.37
, pp. 375-536
-
-
Van Den Steen, E.1
-
107
-
-
33644516283
-
Potent inhibition of macrophage responses to IFN-gamma by live virulent Mycobacterium Tuberculosis is independent of mature mycobacterial lipoproteins but dependent on TLR2
-
Banaiee N et al (2006) Potent inhibition of macrophage responses to IFN-gamma by live virulent Mycobacterium Tuberculosis is independent of mature mycobacterial lipoproteins but dependent on TLR2. J Immunol 176:3019-3027
-
(2006)
J Immunol
, vol.176
, pp. 3019-3027
-
-
Banaiee, N.1
-
108
-
-
2442544416
-
Mycobacterium Tuberculosis inhibits macrophage responses to IFNgamma through myeloid differentiation factor 88-dependent and -independent mechanisms
-
Fortune SM et al (2004) Mycobacterium Tuberculosis inhibits macrophage responses to IFNgamma through myeloid differentiation factor 88-dependent and -independent mechanisms. J Immunol 172:6272-6280
-
(2004)
J Immunol
, vol.172
, pp. 6272-6280
-
-
Fortune, S.M.1
-
109
-
-
0042635767
-
Mycobacterium Tuberculosis exerts gene-selective inhibition of transcriptional responses to IFN-gamma without inhibiting STAT1 function
-
Kincaid EZ, Ernst JD (2003) Mycobacterium Tuberculosis exerts gene-selective inhibition of transcriptional responses to IFN-gamma without inhibiting STAT1 function. J Immunol 171:2042-2049
-
(2003)
J Immunol
, vol.171
, pp. 2042-2049
-
-
Kincaid, E.Z.1
Ernst, J.D.2
-
110
-
-
0033214553
-
Mycobacterium Tuberculosis inhibits IFN-gamma transcriptional responses without inhibiting activation of STAT1
-
Ting LM et al (1999) Mycobacterium Tuberculosis inhibits IFN-gamma transcriptional responses without inhibiting activation of STAT1. J Immunol 163:3898-3906
-
(1999)
J Immunol
, vol.163
, pp. 3898-3906
-
-
Ting, L.M.1
-
111
-
-
66949159845
-
Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection
-
Stockhammer OW et al (2009) Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection. J Immunol 182:5641-5653
-
(2009)
J Immunol
, vol.182
, pp. 5641-5653
-
-
Stockhammer, O.W.1
-
112
-
-
33750475238
-
Role for matrix metalloproteinase 9 in granuloma formation during pulmonary Mycobacterium Tuberculosis infection
-
Taylor JL et al (2006) Role for matrix metalloproteinase 9 in granuloma formation during pulmonary Mycobacterium Tuberculosis infection. Infect Immun 74:6135-6144
-
(2006)
Infect Immun
, vol.74
, pp. 6135-6144
-
-
Taylor, J.L.1
-
113
-
-
17844408723
-
Expression of matrix metalloproteinase-9 in pleural effusions of Tuberculosis and lung cancer
-
Park KJ et al (2005) Expression of matrix metalloproteinase-9 in pleural effusions of Tuberculosis and lung cancer. Respiration 72:166-175
-
(2005)
Respiration
, vol.72
, pp. 166-175
-
-
Park, K.J.1
-
114
-
-
0035869604
-
Identification of a matrix-degrading phenotype in human Tuberculosis in vitro and in vivo
-
Price NM et al (2001) Identification of a matrix-degrading phenotype in human Tuberculosis in vitro and in vivo. J Immunol 166:4223-4230
-
(2001)
J Immunol
, vol.166
, pp. 4223-4230
-
-
Price, N.M.1
-
115
-
-
58849088869
-
High MMP-9 activity characterises pleural Tuberculosis correlating with granuloma formation
-
Sheen P et al (2009) High MMP-9 activity characterises pleural Tuberculosis correlating with granuloma formation. Eur Respir J 33:134-141
-
(2009)
Eur Respir J
, vol.33
, pp. 134-141
-
-
Sheen, P.1
-
116
-
-
34848912309
-
Synergistic up-regulation of epithelial cell matrix metalloproteinase-9 secretion in Tuberculosis
-
Elkington T et al (2007) Synergistic up-regulation of epithelial cell matrix metalloproteinase-9 secretion in Tuberculosis. Am J Respir Cell Mol Biol
-
(2007)
Am J Respir Cell Mol Biol
-
-
Elkington, T.1
-
117
-
-
79953279193
-
Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism
-
Adams KN et al (2011) Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism. Cell 145:39-53
-
(2011)
Cell
, vol.145
, pp. 39-53
-
-
Adams, K.N.1
-
118
-
-
0036078710
-
Dissemination of Mycobacterium Tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity
-
Chackerian AA et al (2002) Dissemination of Mycobacterium Tuberculosis is influenced by host factors and precedes the initiation of T-cell immunity. Infect Immun 70:4501-4509
-
(2002)
Infect Immun
, vol.70
, pp. 4501-4509
-
-
Chackerian, A.A.1
-
119
-
-
80053429660
-
Inflammatory dendritic cells migrate in and out of transplanted chronic mycobacterial granulomas in mice
-
Schreiber HA et al (2011) Inflammatory dendritic cells migrate in and out of transplanted chronic mycobacterial granulomas in mice. J Clin Invest 121:3902-3913
-
(2011)
J Clin Invest
, vol.121
, pp. 3902-3913
-
-
Schreiber, H.A.1
-
120
-
-
0034463942
-
Transient radiographic progression during initial treatment of pulmonary Tuberculosis: CT findings
-
Akira M, Sakatani M, Ishikawa H (2000) Transient radiographic progression during initial treatment of pulmonary Tuberculosis: CT findings. J Comput Assist Tomogr 24:426-431
-
(2000)
J Comput Assist Tomogr
, vol.24
, pp. 426-431
-
-
Akira, M.1
Sakatani, M.2
Ishikawa, H.3
-
121
-
-
0018903350
-
Reversible roentgenographic progression in the initial treatment of pulmonary Tuberculosis
-
Bobrowitz ID (1980) Reversible roentgenographic progression in the initial treatment of pulmonary Tuberculosis. Am Rev Respir Dis 121:735-742
-
(1980)
Am Rev Respir Dis
, vol.121
, pp. 735-742
-
-
Bobrowitz, I.D.1
-
122
-
-
33845683474
-
Who puts the tubercle in Tuberculosis?
-
Russell DG (2007) Who puts the tubercle in Tuberculosis? Nat Rev Microbiol 5:39-47
-
(2007)
Nat Rev Microbiol
, vol.5
, pp. 39-47
-
-
Russell, D.G.1
-
123
-
-
84864296849
-
An in vivo platform for rapid high-throughput antitubercular drug discovery
-
Takaki K et al (2012) An in vivo platform for rapid high-throughput antitubercular drug discovery. Cell Rep 2:175-184
-
(2012)
Cell Rep
, vol.2
, pp. 175-184
-
-
Takaki, K.1
|