Gr1intCD11b+ myeloid-derived suppressor cells in mycobacterium tuberculosis infection

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Obregón Henao, Andrés ^a   Henao Tamayo, Marcela ^a   Orme, Ian M ^a   Ordway, Diane J ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE 1; INTERLEUKIN 17;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; C3HEBFEJ MOUSE; C57BL 6 MOUSE; CD4+ T LYMPHOCYTE; CELL POPULATION; CELL SELECTION; CELLULAR IMMUNITY; CONTROLLED STUDY; GR1INTCD11B+ MYELOID DERIVED SUPPRESSOR CELL; HOST PATHOGEN INTERACTION; LUNG DISEASE; LUNG LESION; LUNG NECROSIS; LUNG TUBERCULOSIS; LYMPHOCYTE PROLIFERATION; MOUSE; MOUSE STRAIN; NONHUMAN; NOS2 MOUSE; PROTEIN EXPRESSION; RAG MOUSE; SPLEEN CELL; SUPPRESSOR CELL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIGENS, CD11B; MICE; MICE, KNOCKOUT; MYCOBACTERIUM INFECTIONS; MYCOBACTERIUM TUBERCULOSIS; MYELOID CELLS; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, CHEMOKINE;

EID: 84891418361     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080669     Document Type: Article

References (53)

1. Jassal MS, Bishai WR (2010) Epidemiology and challenges to the elimination of global tuberculosis. Clin Infect Dis 50 (Suppl 3): S156-S164. doi:10.1086/651486. PubMed: 20397943.
2. Raviglione M, Marais B, Floyd K, Lönnroth K, Getahun H et al. (2010) Scaling up interventions to achieve global tuberculosis control: progress and new developments. Lancet 379: 1902-1913. PubMed: 22608339.
3. Orme IM (2011) Development of new vaccines and drugs for TB: limitations and potential strategic errors. Future Microbiol 6: 161-177. doi:10.2217/fmb.10.168. PubMed: 21366417.
4. Orme IM (2003) The mouse as a useful model of tuberculosis. Tuberculosis (Edinb, Scotland) 83: 112-115. doi:10.1016/S1472-9792(02)00069-0. PubMed: 12758199.
5. Basaraba RJ (2008) Experimental tuberculosis: the role of comparative pathology in the discovery of improved tuberculosis treatment strategies. Tuberculosis (Edinb) 88 (Suppl 1): S35-S47. doi:10.1016/S1472-9792(08)70035-0. PubMed: 18762152.
6. Basaraba RJ, Orme IM (2010) Pulmonary tuberculosis in the guinea pig. In: FY LeongV DartoisDT Baton Rouge, A Color Atlas of comparative pathology of pulmonary tuberculosis. CRC Press.
7. Ehlers S, Schaible UE (2000) The granuloma in tuberculosis: dynamics of a host-pathogen collusion. Frontiers in Immunology 3:411.
8. Hoff DR, Ryan GJ, Driver ER, Ssemakulu CC, De Groote MA et al. (2011) Location of intra- and extracellular M. tuberculosis populations in lungs of mice and guinea pigs during disease progression and after drug treatment. PLOS ONE 6: e17550. doi:10.1371/journal.pone.0017550. PubMed: 21445321.
9. Ordway DJ, Shanley CA, Caraway ML, Orme EA, Bucy DS et al. (2010) Evaluation of standard chemotherapy in the guinea pig model of tuberculosis. Antimicrob Agents Chemother 54: 1820-1833. doi: 10.1128/AAC.01521-09. PubMed: 20160055.
10. Dharmadhikari AS, Basaraba RJ, Van Der Walt ML, Weyer K, Mphahlele M et al. (2011) Natural infection of guinea pigs exposed to patients with highly drug-resistant tuberculosis. Tuberculosis (Edinb, Scotland) 91: 329-338. PubMed: 21478054.
11. Cooper AM, Dalton DK, Stewart TA, Griffin JP, Russell DG et al. (1993) Disseminated tuberculosis in interferon gamma gene-disrupted mice. J Exp Med 178: 2243-2247. doi:10.1084/jem.178.6.2243. PubMed: 8245795.
12. Gonzalez-Juarrero M, Hattle JM, Izzo A, Junqueira-Kipnis AP, Shim TS et al. (2005) Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to control Mycobacterium tuberculosis infection. J Leukoc Biol 77: 914-922. doi:10.1189/jlb.1204723. PubMed: 15767289.
13. Cooper AM, Pearl JE, Brooks JV, Ehlers S, Orme IM (2000) Expression of the nitric oxide synthase 2 gene is not essential for early control of Mycobacterium tuberculosis in the murine lung. Infect Immun 68: 6879-6882. doi:10.1128/IAI.68.12.6879-6882.2000. PubMed: 11083808.
14. Eruslanov EB, Lyadova IV, Kondratieva TK, Majorov KB, Scheglov IV et al. (2005) Neutrophil responses to Mycobacterium tuberculosis infection in genetically susceptible and resistant mice. Infect Immun 73: 1744-1753. doi:10.1128/IAI.73.3.1744-1753.2005. PubMed: 15731075.
15. Pan H, Yan BS, Rojas M, Shebzukhov YV, Zhou H et al. (2005) Ipr1 gene mediates innate immunity to tuberculosis. Nature 434: 767-772. doi:10.1038/nature03419. PubMed: 15815631.
16. Turner OC, Basaraba RJ, Frank AA, Orme IM (2003) Granuloma formation in mouse and guinea pig models of experimental tuberculosis. Granulomatous Infections and Inflammation: Cellular and molecular mechanisms. DL Boros. Washington, D.C.: ASM Press; 65-84.
17. Turner OC, Basaraba RJ, Orme IM (2003) Immunopathogenesis of pulmonary granulomas in the guinea pig after infection with Mycobacterium tuberculosis. Infect Immun 71: 864-871. doi:10.1128/IAI.71.2.864-871.2003. PubMed: 12540568.
18. Palanisamy GS, Kirk NM, Ackart DF, Shanley CA, Orme IM et al. (2011) Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis. PLOS ONE 6: e26254. doi:10.1371/journal.pone.0026254. PubMed: 22028843.
19. Nandi B, Behar SM (2011) Regulation of neutrophils by interferongamma limits lung inflammation during tuberculosis infection. J Exp Med, 208: 2251-2262. doi:10.1084/jem.20110919. PubMed: 21967766.
20. Ordway D, Palanisamy G, Henao-Tamayo M, Smith EE, Shanley C et al. (2007) The cellular immune response to Mycobacterium tuberculosis infection in the guinea pig. J Immunol 179: 2532-2541. PubMed: 17675515.
21. Eum SY, Kong JH, Hong MS, Lee YJ, Kim JH et al. (2012) Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB. Chest 137: 122-128. PubMed: 19749004.
22. Berry MP, Graham CM, McNab FW, Xu Z, Bloch SA et al. (2010) An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 466: 973-977. doi:10.1038/nature09247. PubMed: 20725040.
23. Mazzoni A, Bronte V, Visintin A, Spitzer JH, Apolloni E et al. (2002) Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism. J Immunol 168: 689-695. PubMed: 11777962.
24. Gabrilovich DI, Nagaraj S (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9: 162-174. doi: 10.1038/nri2506. PubMed: 19197294.
25. Nagaraj S, Gabrilovich DI (2008) Tumor escape mechanism governed by myeloid-derived suppressor cells. Cancer Res 68: 2561-2563. doi: 10.1158/0008-5472.CAN-07-6229. PubMed: 18413722.
26. Nagaraj S, Youn J-I, Gabrilovich DI (2013) Reciprocal Relationship between Myeloid-Derived Suppressor Cells and T Cells. J Immunol 191: 17-23. doi:10.4049/jimmunol.1300654. PubMed: 23794702.
27. Raber P, Ochoa AC, Rodríguez PC (2012) Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives. Immunol Investig 41: 614-634. doi:10.3109/ 08820139.2012.680634. PubMed: 23017138.
28. Gonzalez-Juarrero M, Shim TS, Kipnis A, Junqueira-Kipnis AP, Orme IM (2003) Dynamics of macrophage cell populations during murine pulmonary tuberculosis. J Immunol 171: 3128-3135. PubMed: 12960339.
29. Corzo CA, Condamine T, Lu L, Cotter MJ, Youn JI et al. (2009) HIF-1alpha regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. J Exp Med 207: 2439-2453.
30. Driver ER, Ryan GJ, Hoff DR, Irwin SM, Basaraba RJ et al. (2012) Evaluation of a mouse model of necrotic granuloma formation using C3HeB/FeJ mice for testing of drugs against Mycobacterium tuberculosis. Antimicrob Agents Chemother 56: 3181-3195. doi: 10.1128/AAC.00217-12. PubMed: 22470120.
31. Harper J, Skerry C, Davis SL, Tasneen R, Weir M et al. (2012) Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions. J Infect Dis 205: 595-602. doi:10.1093/infdis/jir786. PubMed: 22198962.
32. Kramnik I (2008) Genetic dissection of host resistance to Mycobacterium tuberculosis: the sst1 locus and the Ipr1 gene. Curr Top Microbiol Immunol 321: 123-148. doi:10.1007/978-3-540-75203-5-6. PubMed: 18727490.
33. Nagaraj S, Dmitry I (2012) Regulation of suppressive function of myeloid-derived suppressor cells by CD4+ T cells MDSC and CD4+ T cells. Semin Cancer Biol 22: 282-288. doi:10.1016/j.semcancer. 2012.01.010. PubMed: 22313876.
34. Ordway DJ, Orme IM (2009) Animal models of mycobacteria infection. Curr Protoc Immunol Chapter 19: Unit 195. PubMed: 21809318
35. Rieber N, Brand A, Hector A, Graepler-Mainka U, Ost M et al. (2013) Flagellin Induces Myeloid-Derived Suppressor Cells: Implications for Pseudomonas aeruginosa Infection in Cystic Fibrosis Lung Disease. J Immunol 190(3): 1276-1284. doi:10.4049/jimmunol.1202144. PubMed: 23277486.
36. Zhang C, Lei GS, Shao S, Jung HW, Durant PJ et al. (2013) Accumulation of myeloid-derived suppressor cells in the lungs during Pneumocystis pneumonia. Infect Immun 80: 3634-3641. PubMed: 22868498.
37. Gama L, Shirk EN, Russell JN, Carvalho KI, Li M et al. (2009) Expansion of a subset of CD14highCD16negCCR2low/neg monocytes functionally similar to myeloid-derived suppressor cells during SIV and HIV infection. J Leukoc Biol 91: 803-816. PubMed: 22368280.
38. Vollbrecht T, Stirner R, Tufman A, Roider J, Huber RM et al. (2012) Chronic progressive HIV-1 infection is associated with elevated levels of myeloid-derived suppressor cells. AIDS (London, England) 26:F31-37.
39. Martino A, Badell E, Abadie V, Balloy V, Chignard M et al. (2010) Mycobacterium bovis bacillus Calmette-Guerin vaccination mobilizes innate myeloid-derived suppressor cells restraining in vivo T cell priming via IL-1R-dependent nitric oxide production. J Immunol 184: 2038-2047. doi:10.4049/jimmunol.0903348. PubMed: 20083674.
40. Sköld M, Behar SM (2008) Tuberculosis triggers a tissue-dependent program of differentiation and acquisition of effector functions by circulating monocytes. J Immunol 181: 6349-6360. PubMed: 18941226.
41. Derive M, Bouazza Y, Alauzet C, Gibot S (2012) Myeloid-derived suppressor cells control microbial sepsis. Intensive Care Med 38: 1040-1049. doi:10.1007/s00134-012-2574-4. PubMed: 22552586.
42. Dilek N, Vuillefroy de Silly R, Blancho G, Vanhove B (2012) Myeloid-derived suppressor cells: mechanisms of action and recent advances in their role in transplant tolerance. Frontiers in Immunology 3:208.
43. Ordway DJ, Shang S, Henao-Tamayo M, Obregon-Henao A, Nold L et al. (2011) Mycobacterium bovis BCG-mediated protection against WBeijing strains of Mycobacterium tuberculosis is diminished concomitant with the emergence of regulatory T cells. Clin Vaccine Immunol 18: 1527-1535. doi:10.1128/CVI.05127- 11. PubMed: 21795460.
44. Shang S, Harton M, Tamayo MH, Shanley C, Palanisamy GS et al. (2011) Increased Foxp3 expression in guinea pigs infected with W-Beijing strains of M. tuberculosis. Tuberculosis (Edinb, Scotland) 91: 378-385. doi:10.1016/j.tube. 2011.06.001. PubMed: 21737349.
45. Rodriguez PC, Quiceno DG, Zabaleta J, Ortiz B, Zea AH et al. (2004) Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses. Cancer Res 64: 5839-5849. doi: 10.1158/0008-5472.CAN-04-0465. PubMed: 15313928.
46. Rodriguez PC, Zea AH, Culotta KS, Zabaleta J, Ochoa JB et al. (2002) Regulation of T cell receptor CD3zeta chain expression by L-arginine. J Biol Chem 277: 21123-21129. doi:10.1074/jbc.M110675200. PubMed: 11950832.
47. Rodriguez PC, Zea AH, DeSalvo J, Culotta KS, Zabaleta J (2003) Larginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes. J Immunol 171: 1232-1239. PubMed: 12874210.
48. Zea AH, Culotta KS, Ali J, Mason C, Park HJ et al. (2006) Decreased expression of CD3zeta and nuclear transcription factor kappa B in patients with pulmonary tuberculosis: potential mechanisms and reversibility with treatment. J Infect Dis 194: 1385-1393. doi: 10.1086/508200. PubMed: 17054067.
49. Rodriguez PC, Quiceno DG, Ochoa AC (2007) L-arginine availability regulates T-lymphocyte cell-cycle progression. Blood 109: 1568-1573. doi:10.1182/blood-2006-06-031856. PubMed: 17023580.
50. Pessanha AP, Martins RA, Mattos-Guaraldi AL, Vianna A, Moreira LO (2012) Arginase-1 expression in granulomas of tuberculosis patients. FEMS Immunol Med Microbiol 66: 265-268. doi:10.1111/j.1574-695X.2012.01012.x. PubMed: 22827286.
51. Ino Y, Yamazaki-Itoh R, Oguro S, Shimada K, Kosuge T et al. (2013) Arginase II expressed in cancer-associated fibroblasts indicates tissue hypoxia and predicts poor outcome in patients with pancreatic cancer. PLOS ONE 8: e55146. doi:10.1371/journal.pone.0055146. PubMed: 23424623.
52. Durante W, Johnson FK, Johnson RA (2007) Arginase: a critical regulator of nitric oxide synthesis and vascular function. Clin Exp Pharmacol Physiol 34: 906-911. doi:10.1111/j.1440-1681.2007.04638.x. PubMed: 17645639.
53. Youn JI, Gabrilovich DI (2010) The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity. Eur J Immunol 40: 2969-2975. doi:10.1002/eji.201040895. PubMed: 21061430.