Anaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient mice

Molecular Microbiology

Volumn 35, Issue 5, 2000, Pages 1017-1025

  Weber, Isabel ^a   Fritz, Christian ^a   Ruttkowski, Silvia ^a   Kreft, Andreas ^b   Bange, Franz Christoph ^a,b  

^a Institute of Medical Microbiology   (Germany)

^b HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; BCG VACCINE; NITRATE; NITRATE REDUCTASE;

ACID FAST BACTERIUM; AEROBIC METABOLISM; ANAEROBIC METABOLISM; ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; GENE CLUSTER; GENE DELETION; GENE TARGETING; GRANULOMA; HISTOLOGY; IMMUNE DEFICIENCY; MORTALITY; MOUSE; MYCOBACTERIUM BOVIS; MYCOBACTERIUM SMEGMATIS; NONHUMAN; OXIDATION; PRIORITY JOURNAL; REDUCTION;

ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA PRIMERS; MICE; MICE, INBRED BALB C; MICE, SCID; MUTATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NITRATE REDUCTASE; NITRATE REDUCTASES; PHENOTYPE; VIRULENCE;

ACTINOBACTERIA (CLASS); ANIMALIA; BACILLI; BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM BOVIS BCG; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA; UNCULTURED ACTINOMYCETE;

EID: 0034012134     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2000.01794.x     Document Type: Article

References (35)

1. Aljada, I.S., Crane, J.K., Corriere, N., Wagle, D.G., and Amsterdam, D. (1999) Mycobacterium bovis BCG causing vertebral osteomyelitis (Pott's disease) following intravesical BCG therapy J Clin Microbiol 37: 2106-2108.
2. Altare, F., Lammas, D., Revy, P., Jouanguy, E., Döffinger, R., Lamhamedi, S., et al. (1998) Inherited interleukin 12 deficiency in a child with bacille Calmette-Guerin and Salmonella enteritidis disseminated infection J Clin Invest 102: 2035-2040.
3. Bange, F.-C., Collins, F.M., and Jacobs, Jr, W.R., (1999) Survival of SCID mice infected with Mycobacterium smegmatis containing large DNA fragments from Mycobacterium tuberculosis. Tubercle Lung Dis 79: 171-180.
4. Barclay, R., and Wheeler, P.R. (1989) Metabolism of mycobacteria in tissues. In The Biology of the Mycobacteria, Vol. 3. Ratledge, C., Standford, J., and Grange, J.M. (eds). London: Academic Press, pp. 37-196.
5. Bowyer, L., Hall, R.R., Reading, J., and Marsh, M.M. (1995) The persistence of bacille Calmette-Guerin in the bladder after intravesical treatment for bladder cancer. Br J Urol 75:188-192.
6. Casanova, J.L., Blanche, S., Emile, J.F., Jouanguy, E., Lamhamedi, S., Altare, F., et al. (1996) Idiopathic disseminated bacillus Calmette-Guerin infection: a French national retrospective study Pediatrics 98: 774-778.
7. Cole, S.T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., et al. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence Nature 393: 537-544.
8. Emile, J.F., Patey, N., Altare, F., Lamhamedi, S., Jouanguy, E., Boman, F., et al. (1997) Correlation of granuloma structure with clinical outcome defines two types of idiopathic disseminated BCG infection J Pathol 181: 25-30.
9. Garay, S.M. (1996) Pulmonary tuberculosis. In Tuberculosis, 1st edn. Rom, W.N., and Garay, S.M. (eds). Boston: Little, Brown and Company, pp. 373-412.
10. Gennis, R.B., and Stewart, V. (1996) Respiration. In Escherichia coli and Salmonella, Vol. 1, 2nd edn. Neidhardt, F.C. (ed.). Washington, DC: American Society for Microbiology Press, pp. 408-433.
11. Gordon, S.V., Brosch, R., Billaut, A., Garnier, T., Eigelmeier, K., and Cole, S.T. (1999) Identification of variable regions in the genomes of tubercle bacilli using bacterial artificial chromosome arrays Mol Microbiol 32: 643-655.
12. Guerra, C.E., Betts, R.F., O'Keefe, J.O., and Shilling, J.W. (1998) Mycobacterium bovis osteomyelitis involving a hip arthroplasty after intravesicular Bacille Calmette-Guerin for bladder cancer. Clin Infect Dis 27: 639-640.
13. Guleria, I., Teitelbaum, R., McAdam, R.A., Kalpana, G., Jacobs, Jr, W.R., and Bloom, B.R. (1996) Auxotrophic vaccines for tuberculosis Nature Med 2: 334-337.
14. Hedgecock, L.W., and Costello, R.L. (1962) Utilization of nitrate by pathogenic and saprophytic mycobacteria J Bacteriol 84: 195-205.
15. Jouanguy, E., Altare, F., Lamhamedi, S., Revy, P., Emile, J.-F., Newport, M., et al. (1996) Interferon-γ-receptor deficiency in an infant with fatal bacille Calmette-Guerin infection N Engl J Med 335: 1956-1961.
16. Katz, D.S., Wogalter, H., D'Esposito, R.F., and Cunha, B.A. (1992) Mycobacterium bovis vertebral osteomyelitis and psoas abscess after intravesical BCG therapy for bladder carcinoma. Urology 40: 63-66.
17. Kaufmann, S.H.E. (1993) Immunity to intracellular bacteria Annu Rev Immunol 11: 129-163.
18. Lamm, D.L., van der Meijden, P.M., Morales, A., Brosman, S.A., Catalona, W.J., Herr, H.W., et al. (1992) Incidence and treatment of complications of bacillus Calmette-Guerin intravesical therapy in superficial bladder cancer J Urol 147: 596-600.
19. Metchock, B.G., Nolte, F.S., and Wallace, Jr, R.J. (1999) Mycobacterium. In Manual of Clinical Microbiology, 7th edn. Murray, P.R. (ed.). Washington, DC: American Society for Microbiology Press, pp. 1665-1685.
20. Mortlock, R.P. (1998) Bacterial growth and metabolism. In Systematic Bacteriology, Vol. 2, 9th edn. Balows, A., and Duerden, B.I. (eds). London: Arnold, pp. 85-124.
21. Nakano, M.M., and Zuber, P. (1998) Anaerobic growth of a 'strict aerobe' (Bacillus subtilis). Annu Rev Microbiol 52: 165-190.
22. Newport, M.J., Huxley, C.M., Huston, S., Hawrylowicz, C.M., Oostra, B.A., Williamson, R., and Levin, M. (1996) A mutation in the interferon-γ-receptor gene and susceptibility to mycobacterial infection N Engl J Med 335: 1941-1949.
23. North, R.J., and Izzo, A.A. (1993) Mycobacterial virulence. Virulent strains of Mycobacteria tuberculosis have faster in vivo doubling times and are better equipped to resist growth-inhibiting functions of macrophages in the presence and absence of specific immunity J Exp Med 177: 1723-1733.
24. Nseyo, U.O., and Lamm, D.L. (1997) Immunotherapy of bladder cancer Semin Surg Oncol 13: 342-349.
25. Pavelka, M.S., and Jacobs, Jr, W.R. (1999) Comparison of the construction of unmarked deletion mutations in Mycobacterium smegmatis, Mycobacterium bovis Bacillus Calmette-Guerin and Mycobacterium tuberculosis H37Rv by allelic exchange J Bacteriol 181: 4780-4789.
26. Pelicic, V., Reyrat, J.-M., and Gicquel, B. (1996) Generation of unmarked directed mutations in mycobacteria, using sucrose counter-selectable suicide vectors Mol Microbiol 20: 919-925.
27. Ratledge, C. (1982) Nutrition, growth and metabolism. In The Biology of the Mycobacteria, Vol. 1. Ratledge, C., and Standford, J. (eds). London: Academic Press, pp. 185-271.
28. Raviglione, M.C., Snider, D.E., and Kochi, A. (1995) Global epidemiology of tuberculosis: morbidity and mortality of a worldwide epidemic. J Am Med Assoc 273: 220-226.
29. von Reyn, C.F., Clements, C.J., and Mann, J.M. (1987) Human immunodeficiency virus infection and routine childhood immunisation Lancet 2: 669-672.
30. Rosenfeldt, V., Paerregaard, A., and Valerius, N.H. (1997) Disseminated infection with Bacillus Callmette-Guerin in a child with advanced HIV disease Scand J Infect Dis 29: 526-527.
31. Snapper, S.B., Melton, R.E., Mustafa, S., Kieser, T., and Jacobs, Jr, W.R. (1990) Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis Mol Microbiol 4: 1911-1919.
32. Talbot, E.A., Perkins, M.D., Silva, S.F.M., and Frotingham, R. (1997) Disseminated Bacille Calmette-Guerin disease after vaccination: case report and review. Clin Infect Dis 24: 1139-1146.
33. Virtanen, S. (1960) A study of nitrate reduction by mycobacteria. Acta Tuberc Scand 47 (Suppl.): 1-116.
34. Weltman, A.C., and Rose, D.N. (1993) The safety of Bacille Calmette-Guerin vaccination in HIV infection and AIDS. AIDS 7. 149-157.
35. Wheeler, P.R., and Ratledge, C. (1994) Metabolism of Mycobacterium tuberculosis. In Tuberculosis: Pathogenesis, Protection, and Control. Bloom, B.R. (ed.). Washington, DC: American Society for Microbiology Press.