메뉴 건너뛰기




Volumn 2014, Issue , 2015, Pages

P38 δ MAPK: Emerging Roles of a Neglected Isoform

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR 2 KINASE; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE 13; STATHMIN; TAU PROTEIN; TUMOR PROMOTER;

EID: 84923055142     PISSN: 16878876     EISSN: 16878884     Source Type: Journal    
DOI: 10.1155/2014/272689     Document Type: Review
Times cited : (27)

References (110)
  • 1
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • J. Han, J.-D. Lee, L. Bibbs, and R. J. Ulevitch, "A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells", Science, vol. 265, no. 5173, pp. 808-811, 1994.
    • (1994) Science , vol.265 , Issue.5173 , pp. 808-811
    • Han, J.1    Lee, J.-D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 2
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • J. C. Lee, J. T. Laydon, P. C. McDonnell et al., "A protein kinase involved in the regulation of inflammatory cytokine biosynthesis", Nature, vol. 372, no. 6508, pp. 739-746, 1994.
    • (1994) Nature , vol.372 , Issue.6508 , pp. 739-746
    • Lee, J.C.1    Laydon, J.T.2    McDonnell, P.C.3
  • 3
    • 0028022750 scopus 로고
    • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
    • J. Rouse, P. Cohen, S. Trigon et al., "A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins", Cell, vol. 78, no. 6, pp. 1027-1037, 1994.
    • (1994) Cell , vol.78 , Issue.6 , pp. 1027-1037
    • Rouse, J.1    Cohen, P.2    Trigon, S.3
  • 4
    • 0028015872 scopus 로고
    • Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27
    • N. W. Freshney, L. Rawlinson, F. Guesdon et al., "Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27", Cell, vol. 78, no. 6, pp. 1039-1049, 1994.
    • (1994) Cell , vol.78 , Issue.6 , pp. 1039-1049
    • Freshney, N.W.1    Rawlinson, L.2    Guesdon, F.3
  • 5
    • 0029982565 scopus 로고    scopus 로고
    • Characterization of the structure and function of a newmitogen-activated protein kinase (p38β)
    • Y. Jiang, C. Chen, Z. Li et al., "Characterization of the structure and function of a newmitogen-activated protein kinase (p38β)", The Journal of Biological Chemistry, vol. 271, no. 30, pp. 17920-17926, 1996.
    • (1996) The Journal of Biological Chemistry , vol.271 , Issue.30 , pp. 17920-17926
    • Jiang, Y.1    Chen, C.2    Li, Z.3
  • 7
    • 0030828701 scopus 로고    scopus 로고
    • Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38δ
    • Y. Jiang, H. Gram, M. Zhao et al., "Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38δ", The Journal of Biological Chemistry, vol. 272, no. 48, pp. 30122-30128, 1997.
    • (1997) The Journal of Biological Chemistry , vol.272 , Issue.48 , pp. 30122-30128
    • Jiang, Y.1    Gram, H.2    Zhao, M.3
  • 8
    • 0030756286 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase
    • X. S. Wang, K. Diener, C. L. Manthey et al., "Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase", Journal of Biological Chemistry, vol. 272, no. 38, pp. 23668-23674, 1997.
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.38 , pp. 23668-23674
    • Wang, X.S.1    Diener, K.2    Manthey, C.L.3
  • 9
    • 0030927106 scopus 로고    scopus 로고
    • Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6) ; comparison of its substrate specificity with that of other SAP kinases
    • M. Goedert, A. Cuenda, M. Craxton, R. Jakes, and P. Cohen, "Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6) ; comparison of its substrate specificity with that of other SAP kinases", The EMBO Journal, vol. 16, no. 12, pp. 3563-3571, 1997.
    • (1997) The EMBO Journal , vol.16 , Issue.12 , pp. 3563-3571
    • Goedert, M.1    Cuenda, A.2    Craxton, M.3    Jakes, R.4    Cohen, P.5
  • 10
    • 0027531645 scopus 로고
    • An osmosensing signal transduction pathway in yeast
    • J. L. Brewster, T. de Valoir, N. D. Dwyer, E. Winter, and M. C. Gustin, "An osmosensing signal transduction pathway in yeast", Science, vol. 259, no. 5102, pp. 1760-1763, 1993.
    • (1993) Science , vol.259 , Issue.5102 , pp. 1760-1763
    • Brewster, J.L.1    De Valoir, T.2    Dwyer, N.D.3    Winter, E.4    Gustin, M.C.5
  • 11
    • 80055048292 scopus 로고    scopus 로고
    • Evolutionary history of the vertebrate mitogen activated protein kinases family
    • M. Li, J. Liu, and C. Zhang, "Evolutionary history of the vertebrate mitogen activated protein kinases family", PLoS ONE, vol. 6, no. 10, Article ID e26999, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.10
    • Li, M.1    Liu, J.2    Zhang, C.3
  • 12
    • 0028988138 scopus 로고
    • SE 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • A. Cuenda, J. Rouse, Y. N. Doza et al., "SE 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1", FEBS Letters, vol. 364, no. 2, pp. 229-233, 1995.
    • (1995) FEBS Letters , vol.364 , Issue.2 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3
  • 13
    • 0030954172 scopus 로고    scopus 로고
    • A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket
    • L. Tong, S. Pav, D. M. White et al., "A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket", Nature Structural Biology, vol. 4, no. 4, pp. 311-316, 1997.
    • (1997) Nature Structural Biology , vol.4 , Issue.4 , pp. 311-316
    • Tong, L.1    Pav, S.2    White, D.M.3
  • 14
    • 0032102902 scopus 로고    scopus 로고
    • Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution
    • P. A. Eyers, M. Craxton, N. Morrice, P. Cohen, and M. Goedert, "Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution", Chemistry and Biology, vol. 5, no. 6, pp. 321-328, 1998.
    • (1998) Chemistry and Biology , vol.5 , Issue.6 , pp. 321-328
    • Eyers, P.A.1    Craxton, M.2    Morrice, N.3    Cohen, P.4    Goedert, M.5
  • 15
    • 10744227768 scopus 로고    scopus 로고
    • Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket
    • R. J. Gum, M. M. McLaughlin, S. Kumar et al., "Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB 203580, by alteration of one or more amino acids within the ATP binding pocket", The Journal of Biological Chemistry, vol. 273, no. 25, pp. 15605-15610, 1998.
    • (1998) The Journal of Biological Chemistry , vol.273 , Issue.25 , pp. 15605-15610
    • Gum, R.J.1    McLaughlin, M.M.2    Kumar, S.3
  • 18
    • 0033548597 scopus 로고    scopus 로고
    • Murine p38-δ mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines
    • M. C.-T. Hu, Y.-p. Wang, and A. Mikhail, "Murine p38-δ mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines", Journal of Biological Chemistry, vol. 274, no. 11, pp. 7095-7102, 1999.
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.11 , pp. 7095-7102
    • Hu, M.C.-T.1    Wang Y.-.2    Mikhail, A.3
  • 19
    • 20244365497 scopus 로고    scopus 로고
    • P38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
    • G. Sabio, J. S. C. Arthur, Y. Kuma et al., "p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP", EMBO Journal, vol. 24, no. 6, pp. 1134-1145, 2005.
    • (2005) EMBO Journal , vol.24 , Issue.6 , pp. 1134-1145
    • Sabio, G.1    Arthur, J.S.C.2    Kuma, Y.3
  • 20
    • 27944461325 scopus 로고    scopus 로고
    • Generation and characterization of p38β (MAPK11) gene-targeted mice
    • V. A. Beardmore, H. J. Hinton, C. Eftychi et al., "Generation and characterization of p38β (MAPK11) gene-targeted mice", Molecular and Cellular Biology, vol. 25, no. 23, pp. 10454-10464, 2005.
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.23 , pp. 10454-10464
    • Beardmore, V.A.1    Hinton, H.J.2    Eftychi, C.3
  • 21
    • 0034610981 scopus 로고    scopus 로고
    • Deficiency of the stress kinase p38α results in embryonic lethality: Characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells
    • M. Allen, L. Svensson, M. Roach, J. Hambor, J. McNeish, and C. A. Gabel, "Deficiency of the stress kinase p38α results in embryonic lethality: Characterization of the kinase dependence of stress responses of enzyme-deficient embryonic stem cells", Journal of Experimental Medicine, vol. 191, no. 5, pp. 859-870, 2000.
    • (2000) Journal of Experimental Medicine , vol.191 , Issue.5 , pp. 859-870
    • Allen, M.1    Svensson, L.2    Roach, M.3    Hambor, J.4    McNeish, J.5    Gabel, C.A.6
  • 22
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogenactivated protein kinase activation by dual phosphorylation on tyrosine and threonine
    • J. Raingeaud, S. Gupta, J. S. Rogers et al., "Pro-inflammatory cytokines and environmental stress cause p38 mitogenactivated protein kinase activation by dual phosphorylation on tyrosine and threonine", Journal of Biological Chemistry, vol. 270, no. 13, pp. 7420-7426, 1995.
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.13 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3
  • 23
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • J. M. Kyriakis and J. Avruch, "Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation", Physiological Reviews, vol. 81, no. 2, pp. 807-869, 2001.
    • (2001) Physiological Reviews , vol.81 , Issue.2 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 24
    • 0242473165 scopus 로고    scopus 로고
    • Feedback control of the protein kinase TAK1 by SAPK2a/p38α
    • P. C. F. Cheung, D. G. Campbell, A. R. Nebreda, and P. Cohen, "Feedback control of the protein kinase TAK1 by SAPK2a/p38α", EMBO Journal, vol. 22, no. 21, pp. 5793-5805, 2003.
    • (2003) EMBO Journal , vol.22 , Issue.21 , pp. 5793-5805
    • Cheung, P.C.F.1    Campbell, D.G.2    Nebreda, A.R.3    Cohen, P.4
  • 25
    • 0036731701 scopus 로고    scopus 로고
    • Mixed-lineage kinase control of JNK and p38 MAPK pathways
    • K. A. Gallo and G. L. Johnson, "Mixed-lineage kinase control of JNK and p38 MAPK pathways", Nature Reviews Molecular Cell Biology, vol. 3, no. 9, pp. 663-672, 2002.
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.9 , pp. 663-672
    • Gallo, K.A.1    Johnson, G.L.2
  • 26
    • 14444281569 scopus 로고    scopus 로고
    • Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
    • H. Ichijo, E. Nishida, K. Irie et al., "Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways", Science, vol. 275, no. 5296, pp. 90-94, 1997.
    • (1997) Science , vol.275 , Issue.5296 , pp. 90-94
    • Ichijo, H.1    Nishida, E.2    Irie, K.3
  • 27
    • 0029551805 scopus 로고
    • Identification of a member of the MAPKKK family as a potential Mediator of TGF-β signal transduction
    • K. Yamaguchi, K. Shirakabe, H. Shibuya et al., "Identification of a member of the MAPKKK family as a potential Mediator of TGF-β signal transduction", Science, vol. 270, no. 5244, pp. 2008-2011, 1995.
    • (1995) Science , vol.270 , Issue.5244 , pp. 2008-2011
    • Yamaguchi, K.1    Shirakabe, K.2    Shibuya, H.3
  • 28
    • 34248563299 scopus 로고    scopus 로고
    • Role of mitogenactivated protein kinase kinase kinases in signal integration
    • B. D. Cuevas, A. N. Abell, and G. L. Johnson, "Role of mitogenactivated protein kinase kinase kinases in signal integration", Oncogene, vol. 26, no. 22, pp. 3159-3171, 2007.
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3159-3171
    • Cuevas, B.D.1    Abell, A.N.2    Johnson, G.L.3
  • 29
    • 0028820587 scopus 로고
    • Rho family GT Pases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1
    • S. Zhang, J. Han, M. A. Sells et al., "Rho family GT Pases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1", The Journal of Biological Chemistry, vol. 270, no. 41, pp. 23934-23936, 1995.
    • (1995) The Journal of Biological Chemistry , vol.270 , Issue.41 , pp. 23934-23936
    • Zhang, S.1    Han, J.2    Sells, M.A.3
  • 30
    • 0032977187 scopus 로고    scopus 로고
    • A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: A role for c-Jun. NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5
    • M. J. Marinissen, M. Chiariello, M. Pallante, and J. S. Gutkind, "A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun. NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5", Molecular and Cellular Biology, vol. 19, no. 6, pp. 4289-4301, 1999.
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.6 , pp. 4289-4301
    • Marinissen, M.J.1    Chiariello, M.2    Pallante, M.3    Gutkind, J.S.4
  • 31
    • 74449083698 scopus 로고    scopus 로고
    • Differential activation of p38MAPK isoforms by MKK6 and MKK3
    • G. Remy, A. M. Risco, F. A. Iñesta-Vaquera et al., "Differential activation of p38MAPK isoforms by MKK6 and MKK3", Cellular Signalling, vol. 22, no. 4, pp. 660-667, 2010.
    • (2010) Cellular Signalling , vol.22 , Issue.4 , pp. 660-667
    • Remy, G.1    Risco, A.M.2    Iñesta-Vaquera, F.A.3
  • 32
    • 0038260539 scopus 로고    scopus 로고
    • Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38α and p38δ MAPK isoforms by TGF-β1 in murine mesangial cells
    • L. Wang, R. Ma, R. A. Flavell, and M. E. Choi, "Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38α and p38δ MAPK isoforms by TGF-β1 in murine mesangial cells", The Journal of Biological Chemistry, vol. 277, no. 49, pp. 47257-47262, 2002.
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.49 , pp. 47257-47262
    • Wang, L.1    Ma, R.2    Flavell, R.A.3    Choi, M.E.4
  • 33
    • 0037147297 scopus 로고    scopus 로고
    • Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase
    • J. Schoorlemmer and M. Goldfarb, "Fibroblast growth factor homologous factors and the islet brain-2 scaffold protein regulate activation of a stress-activated protein kinase", Journal of Biological Chemistry, vol. 277, no. 51, pp. 49111-49119, 2002.
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.51 , pp. 49111-49119
    • Schoorlemmer, J.1    Goldfarb, M.2
  • 34
    • 0032585615 scopus 로고    scopus 로고
    • Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro
    • S. Lawler, Y. Fleming, M. Goedert, and P. Cohen, "Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro", Current Biology, vol. 8, no. 25, pp. 1387-1391, 1998.
    • (1998) Current Biology , vol.8 , Issue.25 , pp. 1387-1391
    • Lawler, S.1    Fleming, Y.2    Goedert, M.3    Cohen, P.4
  • 35
    • 0034992168 scopus 로고    scopus 로고
    • MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines
    • C. Tournier, C. Dong, T. K. Turner, S. N. Jones, R. A. Flavell, and R. J. Davis, "MKK7 is an essential component of the JNK signal transduction pathway activated by proinflammatory cytokines", Genes and Development, vol. 15, no. 11, pp. 1419-1426, 2001.
    • (2001) Genes and Development , vol.15 , Issue.11 , pp. 1419-1426
    • Tournier, C.1    Dong, C.2    Turner, T.K.3    Jones, S.N.4    Flavell, R.A.5    Davis, R.J.6
  • 36
    • 0035903222 scopus 로고    scopus 로고
    • Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: Different contribution of SEK2/MKK7 isoforms to the synergistic activation
    • T. Wada, K. Nakagawa, T. Watanabe et al., "Impaired synergistic activation of stress-activated protein kinase SAPK/JNK in mouse embryonic stem cells lacking SEK1/MKK4: different contribution of SEK2/MKK7 isoforms to the synergistic activation", Journal of Biological Chemistry, vol. 276, no. 33, pp. 30892-30897, 2001.
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.33 , pp. 30892-30897
    • Wada, T.1    Nakagawa, K.2    Watanabe, T.3
  • 37
    • 0037083375 scopus 로고    scopus 로고
    • MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha
    • B. Ge, H. Gram, F. di Padova et al., "MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha", Science, vol. 295, no. 5558, pp. 1291-1294, 2002.
    • (2002) Science , vol.295 , Issue.5558 , pp. 1291-1294
    • Ge, B.1    Gram, H.2    Di Padova, F.3
  • 38
    • 16844367955 scopus 로고    scopus 로고
    • Alternative p38 activation pathway mediated by T cell receptorproximal tyrosine kinases
    • J. M. Salvador, P. R. Mittelstadt, T. Guszczynski et al., "Alternative p38 activation pathway mediated by T cell receptorproximal tyrosine kinases", Nature Immunology, vol. 6, no. 4, pp. 390-395, 2005.
    • (2005) Nature Immunology , vol.6 , Issue.4 , pp. 390-395
    • Salvador, J.M.1    Mittelstadt, P.R.2    Guszczynski, T.3
  • 40
    • 33846808922 scopus 로고    scopus 로고
    • Hyperactive variants of p38α induce, whereas hyperactive variants of p38γ suppress, activating protein 1-mediated transcription
    • N. Askari, R. Diskin, M. Avitzour, R. Capone, O. Livnah, and D. Engelberg, "Hyperactive variants of p38α induce, whereas hyperactive variants of p38γ suppress, activating protein 1-mediated transcription", Journal of Biological Chemistry, vol. 282, no. 1, pp. 91-99, 2007.
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.1 , pp. 91-99
    • Askari, N.1    Diskin, R.2    Avitzour, M.3    Capone, R.4    Livnah, O.5    Engelberg, D.6
  • 42
    • 0035854673 scopus 로고    scopus 로고
    • A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs
    • T. Tanoue, T. Yamamoto, R. Maeda, and E. Nishida, "A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs", The Journal of Biological Chemistry, vol. 276, no. 28, pp. 26629-26639, 2001.
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.28 , pp. 26629-26639
    • Tanoue, T.1    Yamamoto, T.2    Maeda, R.3    Nishida, E.4
  • 43
    • 34247613558 scopus 로고    scopus 로고
    • Activation of PKCδ and p38δ MAPK during okadaic acid dependent keratinocyte apoptosis
    • C. A. Kraft, T. Efimova, and R. L. Eckert, "Activation of PKCδ and p38δ MAPK during okadaic acid dependent keratinocyte apoptosis", Archives of Dermatological Research, vol. 299, no. 2, pp. 71-83, 2007.
    • (2007) Archives of Dermatological Research , vol.299 , Issue.2 , pp. 71-83
    • Kraft, C.A.1    Efimova, T.2    Eckert, R.L.3
  • 44
    • 34547154349 scopus 로고    scopus 로고
    • P38 MAP-Kinases pathway regulation, function and role in human diseases
    • A. Cuenda and S. Rousseau, "p38 MAP-Kinases pathway regulation, function and role in human diseases", Biochimica et Biophysica Acta-Molecular Cell Research, vol. 1773, no. 8, pp. 1358-1375, 2007.
    • (2007) Biochimica et Biophysica Acta-molecular Cell Research , vol.1773 , Issue.8 , pp. 1358-1375
    • Cuenda, A.1    Rousseau, S.2
  • 45
    • 0031587929 scopus 로고    scopus 로고
    • Novel homologues of CSBP/p38MAP kinase: Activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
    • S. Kumar, P. C. McDonnell, R. J. Gum, A. T. Hand, J. C. Lee, and P. R. Young, "Novel homologues of CSBP/p38MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles", Biochemical and Biophysical Research Communications, vol. 235, no. 3, pp. 533-538, 1997.
    • (1997) Biochemical and Biophysical Research Communications , vol.235 , Issue.3 , pp. 533-538
    • Kumar, S.1    McDonnell, P.C.2    Gum, R.J.3    Hand, A.T.4    Lee, J.C.5    Young, P.R.6
  • 46
    • 0030963035 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases
    • M. Goedert, M. Hasegawa, R. Jakes, S. Lawler, A. Cuenda, and P. Cohen, "Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases", FEBS Letters, vol. 409, no. 1, pp. 57-62, 1997.
    • (1997) FEBS Letters , vol.409 , Issue.1 , pp. 57-62
    • Goedert, M.1    Hasegawa, M.2    Jakes, R.3    Lawler, S.4    Cuenda, A.5    Cohen, P.6
  • 47
    • 0027308924 scopus 로고
    • Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding
    • G. T. Bramblett, M. Goedert, R. Jakes, S. E. Merrick, J. Q. Trojanowski, and V. M. Y. Lee, "Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding", Neuron, vol. 10, no. 6, pp. 1089-1099, 1993.
    • (1993) Neuron , vol.10 , Issue.6 , pp. 1089-1099
    • Bramblett, G.T.1    Goedert, M.2    Jakes, R.3    Merrick, S.E.4    Trojanowski, J.Q.5    Lee, V.M.Y.6
  • 48
    • 0035370261 scopus 로고    scopus 로고
    • The significance of tau and α-synuclein inclusions in neurodegenerative diseases
    • M. Goedert, "The significance of tau and α-synuclein inclusions in neurodegenerative diseases", Current Opinion in Genetics and Development, vol. 11, no. 3, pp. 343-351, 2001.
    • (2001) Current Opinion in Genetics and Development , vol.11 , Issue.3 , pp. 343-351
    • Goedert, M.1
  • 51
    • 0030783012 scopus 로고    scopus 로고
    • Stathmin: A tubulin-sequestering protein which forms a ternary T2S complexwith twotubulinmolecules
    • L. Jourdain, P. Curmi, A. Sobel, D. Pantaloni, and M.-F. Carlier, "Stathmin: a tubulin-sequestering protein which forms a ternary T2S complexwith twotubulinmolecules", Biochemistry, vol. 36, no. 36, pp. 10817-10821, 1997.
    • (1997) Biochemistry , vol.36 , Issue.36 , pp. 10817-10821
    • Jourdain, L.1    Curmi, P.2    Sobel, A.3    Pantaloni, D.4    Carlier, M.-F.5
  • 53
    • 0035881737 scopus 로고    scopus 로고
    • A novel method to identify protein kinase substrates: Eef2 kinase is phosphorylated and inhibited by SAPK4/p38δ
    • A. Knebel, N. Morrice, and P. Cohen, "A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38δ", EMBO Journal, vol. 20, no. 16, pp. 4360-4369, 2001.
    • (2001) EMBO Journal , vol.20 , Issue.16 , pp. 4360-4369
    • Knebel, A.1    Morrice, N.2    Cohen, P.3
  • 55
    • 84873810502 scopus 로고    scopus 로고
    • Eukaryotic elongation factor 2 controls TNF-alpha translation in LPSinduced hepatitis
    • B. Gonzalez-Teran, J. R. Cortes, E. Manieri et al., "Eukaryotic elongation factor 2 controls TNF-alpha translation in LPSinduced hepatitis", The Journal of Clinical Investigation, vol. 123, no. 1, pp. 164-178, 2013.
    • (2013) The Journal of Clinical Investigation , vol.123 , Issue.1 , pp. 164-178
    • Gonzalez-Teran, B.1    Cortes, J.R.2    Manieri, E.3
  • 56
    • 77951900503 scopus 로고    scopus 로고
    • P38delta mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis
    • T. Efimova, "p38delta mitogen-activated protein kinase regulates skin homeostasis and tumorigenesis", Cell Cycle, vol. 9, no. 3, pp. 498-505, 2010.
    • (2010) Cell Cycle , vol.9 , Issue.3 , pp. 498-505
    • Efimova, T.1
  • 58
    • 0037127310 scopus 로고    scopus 로고
    • Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes
    • S. Balasubramanian, T. Efimova, and R. L. Eckert, "Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes", The Journal of Biological Chemistry, vol. 277, no. 3, pp. 1828-1836, 2002.
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.3 , pp. 1828-1836
    • Balasubramanian, S.1    Efimova, T.2    Eckert, R.L.3
  • 59
    • 0037200008 scopus 로고    scopus 로고
    • Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38δ mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein α
    • T. Efimova, A. Deucher, T. Kuroki, M. Ohba, and R. L. Eckert, "Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38δ mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein α", The Journal of Biological Chemistry, vol. 277, no. 35, pp. 31753-31760, 2002.
    • (2002) The Journal of Biological Chemistry , vol.277 , Issue.35 , pp. 31753-31760
    • Efimova, T.1    Deucher, A.2    Kuroki, T.3    Ohba, M.4    Eckert, R.L.5
  • 60
    • 0035920148 scopus 로고    scopus 로고
    • MEK6 regulates human involucrin gene expression via a p38α- and p38δ-dependent mechanism
    • S. R. Dashti, T. Efimova, and R. L. Eckert, "MEK6 regulates human involucrin gene expression via a p38α- and p38δ-dependent mechanism", Journal of Biological Chemistry, vol. 276, no. 29, pp. 27214-27220, 2001.
    • (2001) Journal of Biological Chemistry , vol.276 , Issue.29 , pp. 27214-27220
    • Dashti, S.R.1    Efimova, T.2    Eckert, R.L.3
  • 61
    • 0141557549 scopus 로고    scopus 로고
    • A regulatory role for p38delta MAPK in keratinocyte differentiation: Evidence for p38delta-ERK1/2 complex formation
    • T. Efimova, A.-M. Broome, and R. L. Eckert, "A regulatory role for p38delta MAPK in keratinocyte differentiation: evidence for p38delta-ERK1/2 complex formation", The Journal of Biological Chemistry, vol. 278, no. 36, pp. 34277-34285, 2003.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.36 , pp. 34277-34285
    • Efimova, T.1    Broome, A.-M.2    Eckert, R.L.3
  • 62
    • 4143139930 scopus 로고    scopus 로고
    • Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38
    • R. Jans, G. Atanasova, M. Jadot, and Y. Poumay, "Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38", Journal of Investigative Dermatology, vol. 123, no. 3, pp. 564-573, 2004.
    • (2004) Journal of Investigative Dermatology , vol.123 , Issue.3 , pp. 564-573
    • Jans, R.1    Atanasova, G.2    Jadot, M.3    Poumay, Y.4
  • 63
    • 0035896611 scopus 로고    scopus 로고
    • MEK7-dependent activation of p38 MAP kinase in keratinocytes
    • S. R. Dashti, T. Efimova, and R. L. Eckert, "MEK7-dependent activation of p38 MAP kinase in keratinocytes", The Journal of Biological Chemistry, vol. 276, no. 11, pp. 8059-8063, 2001.
    • (2001) The Journal of Biological Chemistry , vol.276 , Issue.11 , pp. 8059-8063
    • Dashti, S.R.1    Efimova, T.2    Eckert, R.L.3
  • 64
    • 84896736512 scopus 로고    scopus 로고
    • P38delta mitogenactivated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes
    • E. Siljamäki, L. Raiko, M. Toriseva et al., "p38delta mitogenactivated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes", Archives of Dermatological Research, vol. 306, no. 2, pp. 131-141, 2014.
    • (2014) Archives of Dermatological Research , vol.306 , Issue.2 , pp. 131-141
    • Siljamäki, E.1    Raiko, L.2    Toriseva, M.3
  • 65
    • 33645026707 scopus 로고    scopus 로고
    • Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia
    • A. S. Haider, S. B. Peters, H. Kaporis et al., "Genomic analysis defines a cancer-specific gene expression signature for human squamous cell carcinoma and distinguishes malignant hyperproliferation from benign hyperplasia", Journal of Investigative Dermatology, vol. 126, no. 4, pp. 869-881, 2006.
    • (2006) Journal of Investigative Dermatology , vol.126 , Issue.4 , pp. 869-881
    • Haider, A.S.1    Peters, S.B.2    Kaporis, H.3
  • 68
    • 0033120590 scopus 로고    scopus 로고
    • Differential expression and activation of p38 mitogen-activated protein kinase α, β, γ, and δ in inflammatory cell lineages
    • K. K. Hale, D. Trollinger, M. Rihanek, and C. L. Manthey, "Differential expression and activation of p38 mitogen-activated protein kinase α, β, γ, and δ in inflammatory cell lineages", The Journal of Immunology, vol. 162, no. 7, pp. 4246-4252, 1999.
    • (1999) The Journal of Immunology , vol.162 , Issue.7 , pp. 4246-4252
    • Hale, K.K.1    Trollinger, D.2    Rihanek, M.3    Manthey, C.L.4
  • 69
    • 84879769368 scopus 로고    scopus 로고
    • Acceleration of bone repair in NOD/SCID mice by human Monoosteophils, novel LL-37-activated monocytes
    • Z. Zhang and J. E. Shively, "Acceleration of bone repair in NOD/SCID mice by human Monoosteophils, novel LL-37-activated monocytes", PLoS ONE, vol. 8, no. 7, Article ID e67649, 2013.
    • (2013) PLoS ONE , vol.8 , Issue.7
    • Zhang, Z.1    Shively, J.E.2
  • 70
    • 0034141898 scopus 로고    scopus 로고
    • Epidermal differentiation, apoptosis, and senescence: Common pathways?
    • A. Gandarillas, "Epidermal differentiation, apoptosis, and senescence: common pathways?" Experimental Gerontology, vol. 35, no. 1, pp. 53-62, 2000.
    • (2000) Experimental Gerontology , vol.35 , Issue.1 , pp. 53-62
    • Gandarillas, A.1
  • 71
    • 4444333436 scopus 로고    scopus 로고
    • Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex
    • T. Efimova, A.-M. Broome, and R. L. Eckert, "Protein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complex", Molecular and Cellular Biology, vol. 24, no. 18, pp. 8167-8183, 2004.
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.18 , pp. 8167-8183
    • Efimova, T.1    Broome, A.-M.2    Eckert, R.L.3
  • 72
    • 58249087541 scopus 로고    scopus 로고
    • Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis
    • G. Sumara, I. Formentini, S. Collins et al., "Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis", Cell, vol. 136, no. 2, pp. 235-248, 2009.
    • (2009) Cell , vol.136 , Issue.2 , pp. 235-248
    • Sumara, G.1    Formentini, I.2    Collins, S.3
  • 73
    • 3042742246 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase p38 mediates reduced nerve conduction in experimental diabetic neuropathy: Interactions with aldose reductase
    • S. A. Price, S. Agthong, A. B. Middlemas, and D. R. Tomlinson, "Mitogen-activated protein kinase p38 mediates reduced nerve conduction in experimental diabetic neuropathy: interactions with aldose reductase", Diabetes, vol. 53, no. 7, pp. 1851-1856, 2004.
    • (2004) Diabetes , vol.53 , Issue.7 , pp. 1851-1856
    • Price, S.A.1    Agthong, S.2    Middlemas, A.B.3    Tomlinson, D.R.4
  • 75
    • 84871914752 scopus 로고    scopus 로고
    • Regulation of PTEN activity by p38delta-PKD1 signaling in neutrophils confers inflammatory responses in the lung
    • A. Ittner, H. Block, C. A. Reichel et al., "Regulation of PTEN activity by p38delta-PKD1 signaling in neutrophils confers inflammatory responses in the lung", Journal of Experimental Medicine, vol. 209, no. 12, pp. 2229-2246, 2012.
    • (2012) Journal of Experimental Medicine , vol.209 , Issue.12 , pp. 2229-2246
    • Ittner, A.1    Block, H.2    Reichel, C.A.3
  • 76
    • 0034604129 scopus 로고    scopus 로고
    • The acute respiratory distress syndrome
    • L. B. Ware and M. A. Matthay, "The acute respiratory distress syndrome", New England Journal of Medicine, vol. 342, no. 18, pp. 1334-1349, 2000.
    • (2000) New England Journal of Medicine , vol.342 , Issue.18 , pp. 1334-1349
    • Ware, L.B.1    Matthay, M.A.2
  • 77
    • 55849095891 scopus 로고    scopus 로고
    • Evidence that cytokines play a role in rheumatoid arthritis
    • F. M. Brennan and I. B. McInnes, "Evidence that cytokines play a role in rheumatoid arthritis", The Journal of Clinical Investigation, vol. 118, no. 11, pp. 3537-3545, 2008.
    • (2008) The Journal of Clinical Investigation , vol.118 , Issue.11 , pp. 3537-3545
    • Brennan, F.M.1    McInnes, I.B.2
  • 78
    • 33749370145 scopus 로고    scopus 로고
    • Differential tissue expression and activation of p38 MAPK α, β, γ, and δ isoforms in rheumatoid arthritis
    • A. Korb, M. Tohidast-Akrad, E. Cetin, R. Axmann, J. Smolen, and G. Schett, "Differential tissue expression and activation of p38 MAPK α, β, γ, and δ isoforms in rheumatoid arthritis", Arthritis and Rheumatism, vol. 54, no. 9, pp. 2745-2756, 2006.
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.9 , pp. 2745-2756
    • Korb, A.1    Tohidast-Akrad, M.2    Cetin, E.3    Axmann, R.4    Smolen, J.5    Schett, G.6
  • 80
    • 0037812532 scopus 로고    scopus 로고
    • Characterization of airway plugging in fatal asthma
    • L. M. Kuyper, P. D. Paré, J. C. Hogg et al., "Characterization of airway plugging in fatal asthma", American Journal of Medicine, vol. 115, no. 1, pp. 6-11, 2003.
    • (2003) American Journal of Medicine , vol.115 , Issue.1 , pp. 6-11
    • Kuyper, L.M.1    Paré, P.D.2    Hogg, J.C.3
  • 81
    • 44949257271 scopus 로고    scopus 로고
    • Persistent activation of an innateimmune response translates respiratory viral infection into chronic lung disease
    • E. Y. Kim, J. T. Battaile, A. C. Patel et al., "Persistent activation of an innateimmune response translates respiratory viral infection into chronic lung disease", Nature Medicine, vol. 14, no. 6, pp. 633-640, 2008.
    • (2008) Nature Medicine , vol.14 , Issue.6 , pp. 633-640
    • Kim, E.Y.1    Battaile, J.T.2    Patel, A.C.3
  • 82
    • 0032545213 scopus 로고    scopus 로고
    • Interleukin-13: Central mediator of allergic asthma
    • M. Wills-Karp, J. Luyimbazi, X. Xu et al., "Interleukin-13: central mediator of allergic asthma", Science, vol. 282, no. 5397, pp. 2258-2261, 1998.
    • (1998) Science , vol.282 , Issue.5397 , pp. 2258-2261
    • Wills-Karp, M.1    Luyimbazi, J.2    Xu, X.3
  • 83
    • 84870520781 scopus 로고    scopus 로고
    • IL-13-induced airwaymucus production is attenuated by MAPK13 inhibition
    • Y. G. Alevy, A. C. Patel, A. G. Romero et al., "IL-13-induced airwaymucus production is attenuated by MAPK13 inhibition", Journal of Clinical Investigation, vol. 122, no. 12, pp. 4555-4568, 2012.
    • (2012) Journal of Clinical Investigation , vol.122 , Issue.12 , pp. 4555-4568
    • Alevy, Y.G.1    Patel, A.C.2    Romero, A.G.3
  • 85
    • 34547809513 scopus 로고    scopus 로고
    • P38α and p38δ mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells
    • M. R. Junttila, R. Ala-Aho, T. Jokilehto et al., "p38α and p38δ mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells", Oncogene, vol. 26, no. 36, pp. 5267-5279, 2007.
    • (2007) Oncogene , vol.26 , Issue.36 , pp. 5267-5279
    • Junttila, M.R.1    Ala-Aho, R.2    Jokilehto, T.3
  • 86
    • 33749257848 scopus 로고    scopus 로고
    • CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPKMAPKAP-K2-HSP27 pathway
    • S. Rousseau, I. Dolado, V. Beardmore et al., "CXCL12 and C5a trigger cell migration via a PAK1/2-p38alpha MAPKMAPKAP-K2-HSP27 pathway", Cellular Signalling, vol. 18, no. 11, pp. 1897-1905, 2006.
    • (2006) Cellular Signalling , vol.18 , Issue.11 , pp. 1897-1905
    • Rousseau, S.1    Dolado, I.2    Beardmore, V.3
  • 87
    • 7644223136 scopus 로고    scopus 로고
    • P38 MAP kinase's emerging role as a tumor suppressor
    • D. V. Bulavin and A. J. Fornace Jr., "p38 MAP kinase's emerging role as a tumor suppressor", Advances in Cancer Research, vol. 92, pp. 95-118, 2004.
    • (2004) Advances in Cancer Research , vol.92 , pp. 95-118
    • Bulavin, D.V.1    Fornace, A.J.2
  • 88
    • 34249807348 scopus 로고    scopus 로고
    • P38αMAPkinase is essential in lung stem and progenitor cell proliferation and differentiation
    • J. J. Ventura, S. Tenbaum, E. Perdiguero et al., "p38αMAPkinase is essential in lung stem and progenitor cell proliferation and differentiation", Nature Genetics, vol. 39, no. 6, pp. 750-758, 2007.
    • (2007) Nature Genetics , vol.39 , Issue.6 , pp. 750-758
    • Ventura, J.J.1    Tenbaum, S.2    Perdiguero, E.3
  • 89
    • 35848938280 scopus 로고    scopus 로고
    • P38α: A suppressor of cell proliferation and tumorigenesis
    • L. Hui, L. Bakiri, E. Stepniak, and E. F. Wagner, "p38α: a suppressor of cell proliferation and tumorigenesis", Cell Cycle, vol. 6, no. 20, pp. 2429-2433, 2007.
    • (2007) Cell Cycle , vol.6 , Issue.20 , pp. 2429-2433
    • Hui, L.1    Bakiri, L.2    Stepniak, E.3    Wagner, E.F.4
  • 90
    • 77951248825 scopus 로고    scopus 로고
    • P38delta/MAPK13 as a diagnostic marker for cholangiocarcinoma and its involvement in cell motility and invasion
    • F. L.-S. Tan, A. Ooi, D. Huang et al., "p38delta/MAPK13 as a diagnostic marker for cholangiocarcinoma and its involvement in cell motility and invasion", International Journal of Cancer, vol. 126, no. 10, pp. 2353-2361, 2010.
    • (2010) International Journal of Cancer , vol.126 , Issue.10 , pp. 2353-2361
    • Tan, F.L.-S.1    Ooi, A.2    Huang, D.3
  • 91
    • 0036512208 scopus 로고    scopus 로고
    • New functions for the matrix metalloproteinases in cancer progression
    • M. Egeblad and Z. Werb, "New functions for the matrix metalloproteinases in cancer progression", Nature Reviews Cancer, vol. 2, no. 3, pp. 161-174, 2002.
    • (2002) Nature Reviews Cancer , vol.2 , Issue.3 , pp. 161-174
    • Egeblad, M.1    Werb, Z.2
  • 92
    • 66349138173 scopus 로고    scopus 로고
    • P38delta Mitogen-activated protein kinase is essential for skin tumor development in mice
    • E. M. Schindler, A. Hindes, E. L. Gribben et al., "p38delta Mitogen-activated protein kinase is essential for skin tumor development in mice", Cancer Research, vol. 69, no. 11, pp. 4648-4655, 2009.
    • (2009) Cancer Research , vol.69 , Issue.11 , pp. 4648-4655
    • Schindler, E.M.1    Hindes, A.2    Gribben, E.L.3
  • 93
    • 33645072441 scopus 로고    scopus 로고
    • P44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1) - Dependent signaling contributes to epithelial skin carcinogenesis
    • C. Bourcier, A. Jacquel, J. Hess et al., "p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1) - dependent signaling contributes to epithelial skin carcinogenesis", Cancer Research, vol. 66, no. 5, pp. 2700-2707, 2006.
    • (2006) Cancer Research , vol.66 , Issue.5 , pp. 2700-2707
    • Bourcier, C.1    Jacquel, A.2    Hess, J.3
  • 95
    • 34547897027 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis
    • J. K. Dae, K. S. Chan, S. Sano, and J. Di Giovanni, "Signal transducer and activator of transcription 3 (Stat3) in epithelial carcinogenesis", Molecular Carcinogenesis, vol. 46, no. 8, pp. 725-731, 2007.
    • (2007) Molecular Carcinogenesis , vol.46 , Issue.8 , pp. 725-731
    • Dae, J.K.1    Chan, K.S.2    Sano, S.3    Di Giovanni, J.4
  • 96
    • 39149129602 scopus 로고    scopus 로고
    • Forced expression of a constitutively active formof Stat3 inmouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis
    • K. S. Chan, S. Sano, K. Kataoka et al., "Forced expression of a constitutively active formof Stat3 inmouse epidermis enhances malignant progression of skin tumors induced by two-stage carcinogenesis", Oncogene, vol. 27, no. 8, pp. 1087-1094, 2008.
    • (2008) Oncogene , vol.27 , Issue.8 , pp. 1087-1094
    • Chan, K.S.1    Sano, S.2    Kataoka, K.3
  • 97
    • 4944239032 scopus 로고    scopus 로고
    • Disruptionof Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis
    • K. S. Chan, S. Sano, K. Kiguchi et al., "Disruptionof Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis", Journal of Clinical Investigation, vol. 114, no. 5, pp. 720-728, 2004.
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.5 , pp. 720-728
    • Chan, K.S.1    Sano, S.2    Kiguchi, K.3
  • 98
    • 79960051270 scopus 로고    scopus 로고
    • Evidence of p38γ and p38δ involvement in cell transformation processes
    • M. I. Cerezo-guisado, P. del Reino, G. Remy et al., "Evidence of p38γ and p38δ involvement in cell transformation processes", Carcinogenesis, vol. 32, no. 7, pp. 1093-1099, 2011.
    • (2011) Carcinogenesis , vol.32 , Issue.7 , pp. 1093-1099
    • Cerezo-guisado, M.I.1    Del Reino, P.2    Remy, G.3
  • 99
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • D. Hanahan and R. A. Weinberg, "Hallmarks of cancer: the next generation", Cell, vol. 144, no. 5, pp. 646-674, 2011.
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 100
    • 84879629285 scopus 로고    scopus 로고
    • Loss of p38δ expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth
    • C. O'Callaghan, L. J. Fanning, A. Houston, and O. P. Barry, "Loss of p38δ expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth", International Journal of Oncology, vol. 43, no. 2, pp. 405-415, 2013.
    • (2013) International Journal of Oncology , vol.43 , Issue.2 , pp. 405-415
    • O'Callaghan, C.1    Fanning, L.J.2    Houston, A.3    Barry, O.P.4
  • 101
    • 84934948982 scopus 로고    scopus 로고
    • P38delta MAPK phenotype: An indicator of chemotherapeutic response in oesophageal squamous cell carcinoma
    • C. O'Callaghan, L. J. Fanning, and O. P. Barry, "p38delta MAPK phenotype: an indicator of chemotherapeutic response in oesophageal squamous cell carcinoma", Anti-Cancer Drugs, 2014.
    • (2014) Anti-cancer Drugs
    • O'Callaghan, C.1    Fanning, L.J.2    Barry, O.P.3
  • 102
    • 84890870706 scopus 로고    scopus 로고
    • Brain-metastatic triplenegative breast cancer cells regain growth ability by altering gene expression patterns
    • Y. K. Choi, S.-M. Woo, S.-G. Cho et al., "Brain-metastatic triplenegative breast cancer cells regain growth ability by altering gene expression patterns", Cancer Genomics and Proteomics, vol. 10, no. 6, pp. 265-275, 2013.
    • (2013) Cancer Genomics and Proteomics , vol.10 , Issue.6 , pp. 265-275
    • Choi, Y.K.1    Woo, S.-M.2    Cho, S.-G.3
  • 103
    • 71549131914 scopus 로고    scopus 로고
    • Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma
    • Y. Goto, K. Shinjo, Y. Kondo et al., "Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma", Cancer Research, vol. 69, no. 23, pp. 9073-9082, 2009.
    • (2009) Cancer Research , vol.69 , Issue.23 , pp. 9073-9082
    • Goto, Y.1    Shinjo, K.2    Kondo, Y.3
  • 104
    • 84879713307 scopus 로고    scopus 로고
    • Genome-wide promoter methylation analysis identifies epigenetic silencing of MAPK13 in primary cutaneous melanoma
    • L. Gao, M. A. Smit, J. J. van den Oord et al., "Genome-wide promoter methylation analysis identifies epigenetic silencing of MAPK13 in primary cutaneous melanoma", Pigment Cell and Melanoma Research, vol. 26, no. 4, pp. 542-554, 2013.
    • (2013) Pigment Cell and Melanoma Research , vol.26 , Issue.4 , pp. 542-554
    • Gao, L.1    Smit, M.A.2    Van Den Oord, J.J.3
  • 105
    • 68149108556 scopus 로고    scopus 로고
    • Genome-wide screen of promoter methylation identifies novel markers in melanoma
    • Y. Koga, M. Pelizzola, E. Cheng et al., "Genome-wide screen of promoter methylation identifies novel markers in melanoma", Genome Research, vol. 19, no. 8, pp. 1462-1470, 2009.
    • (2009) Genome Research , vol.19 , Issue.8 , pp. 1462-1470
    • Koga, Y.1    Pelizzola, M.2    Cheng, E.3
  • 106
    • 84857975133 scopus 로고    scopus 로고
    • New insights into the p38gamma and p38delta MAPK pathways
    • A. Risco and A. Cuenda, "New insights into the p38gamma and p38delta MAPK pathways", Journal of Signal Transduction, vol. 2012, Article ID 520289, 8 pages, 2012.
    • (2012) Journal of Signal Transduction , vol.2012
    • Risco, A.1    Cuenda, A.2
  • 107
    • 77955059513 scopus 로고    scopus 로고
    • Mechanisms and functions of p38 MAPK signalling
    • A. Cuadrado and A. R. Nebreda, "Mechanisms and functions of p38 MAPK signalling", Biochemical Journal, vol. 429, no. 3, pp. 403-417, 2010.
    • (2010) Biochemical Journal , vol.429 , Issue.3 , pp. 403-417
    • Cuadrado, A.1    Nebreda, A.R.2
  • 108
    • 84860165740 scopus 로고    scopus 로고
    • Mammalian MAPK signal transduction pathways activated by stress and inflammation: A 10-year update
    • J. M. Kyriakis and J. Avruch, "Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update", Physiological Reviews, vol. 92, no. 2, pp. 689-737, 2012.
    • (2012) Physiological Reviews , vol.92 , Issue.2 , pp. 689-737
    • Kyriakis, J.M.1    Avruch, J.2
  • 109
    • 41949131741 scopus 로고    scopus 로고
    • P38MAPKδ controls c-Myb degradation in response to stress
    • E. Pani and S. Ferrari, "p38MAPKδ controls c-Myb degradation in response to stress", Blood Cells, Molecules, and Diseases, vol. 40, no. 3, pp. 388-394, 2008.
    • (2008) Blood Cells, Molecules, and Diseases , vol.40 , Issue.3 , pp. 388-394
    • Pani, E.1    Ferrari, S.2
  • 110
    • 84865016316 scopus 로고    scopus 로고
    • Delayed cell cycle progression in selenoprotein w-depleted cells is regulated by a mitogenactivated protein kinase kinase 4-p38/c-Jun. NH 2-terminal kinase-p53 pathway
    • W. C. Hawkes and Z. Alkan, "Delayed cell cycle progression in selenoprotein w-depleted cells is regulated by a mitogenactivated protein kinase kinase 4-p38/c-Jun. NH 2-terminal kinase-p53 pathway", Journal of Biological Chemistry, vol. 287, no. 33, pp. 27371-27379, 2012.
    • (2012) Journal of Biological Chemistry , vol.287 , Issue.33 , pp. 27371-27379
    • Hawkes, W.C.1    Alkan, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.