메뉴 건너뛰기




Volumn 40, Issue 1, 2012, Pages 79-84

Roles of p38 MAPKs in invasion and metastasis

Author keywords

Cancer; Metastasis; p38 mitogen activated protein kinase (p38 MAPK); Tumour cell

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 84856243776     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20110676     Document Type: Review
Times cited : (126)

References (60)
  • 1
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: From dissemination to organ-specific colonization
    • Nguyen, D.X., Bos, P.D. and Massague, J. (2009) Metastasis: from dissemination to organ-specific colonization. Nat. Rev. Cancer 9, 274-284
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massague, J.3
  • 2
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery, J.P., Acloque, H., Huang, R.Y. and Nieto, M.A. (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139, 871-890
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 3
    • 35548936833 scopus 로고    scopus 로고
    • Models, mechanisms and clinical evidence for cancer dormancy
    • Aguirre-Ghiso, J.A. (2007) Models, mechanisms and clinical evidence for cancer dormancy. Nat. Rev. Cancer 7, 834-846
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 834-846
    • Aguirre-Ghiso, J.A.1
  • 4
    • 63049104211 scopus 로고    scopus 로고
    • Microenvironmental regulation of metastasis
    • Joyce, J.A. and Pollard, J.W. (2009) Microenvironmental regulation of metastasis. Nat. Rev. Cancer 9, 239-252
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 239-252
    • Joyce, J.A.1    Pollard, J.W.2
  • 5
    • 77955059513 scopus 로고    scopus 로고
    • Mechanisms and functions of p38 MAPK signalling
    • Cuadrado, A. and Nebreda, A.R. (2010) Mechanisms and functions of p38 MAPK signalling. Biochem. J. 429, 403-417
    • (2010) Biochem. J. , vol.429 , pp. 403-417
    • Cuadrado, A.1    Nebreda, A.R.2
  • 6
    • 7644223136 scopus 로고    scopus 로고
    • p38 MAP kinase's emerging role as a tumor suppressor
    • DOI 10.1016/S0065-230X(04)92005-2, PII S0065230X04920052
    • Bulavin, D.V. and Fornace, Jr, A.J. (2004) p38 MAP kinase's emerging role as a tumor suppressor. Adv. Cancer Res. 92, 95-118 (Pubitemid 39458114)
    • (2004) Advances in Cancer Research , vol.92 , pp. 95-118
    • Bulavin, D.V.1    Fornace Jr., A.J.2
  • 7
    • 67749117934 scopus 로고    scopus 로고
    • Signal integration by JNK and p38 MAPK pathways in cancer development
    • Wagner, E.F. and Nebreda, A.R. (2009) Signal integration by JNK and p38 MAPK pathways in cancer development. Nat. Rev. Cancer 9, 537-549
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 537-549
    • Wagner, E.F.1    Nebreda, A.R.2
  • 8
    • 79957883313 scopus 로고    scopus 로고
    • Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness
    • Hong, J., Zhou, J., Fu, J., He, T., Qin, J., Wang, L., Liao, L. and Xu, J. (2011) Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness. Cancer Res. 71, 3980-3990
    • (2011) Cancer Res. , vol.71 , pp. 3980-3990
    • Hong, J.1    Zhou, J.2    Fu, J.3    He, T.4    Qin, J.5    Wang, L.6    Liao, L.7    Xu, J.8
  • 10
    • 33744544424 scopus 로고    scopus 로고
    • p38 and a p38-Interacting Protein Are Critical for Downregulation of E-Cadherin during Mouse Gastrulation
    • DOI 10.1016/j.cell.2006.03.048, PII S0092867406005630
    • Zohn, I.E., Li, Y., Skolnik, E.Y., Anderson, K.V., Han, J. and Niswander, L. (2006) p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation. Cell 125, 957-969 (Pubitemid 43810156)
    • (2006) Cell , vol.125 , Issue.5 , pp. 957-969
    • Zohn, I.E.1    Li, Y.2    Skolnik, E.Y.3    Anderson, K.V.4    Han, J.5    Niswander, L.6
  • 11
    • 33846811520 scopus 로고    scopus 로고
    • p38α MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis
    • DOI 10.1016/j.ccr.2006.12.013, PII S1535610806003801
    • Dolado, I., Swat, A., Ajenjo, N., De Vita, G., Cuadrado, A. and Nebreda, A.R. (2007) p38α MAP kinase as a sensor of reactive oxygen species in tumorigenesis. Cancer Cell 11, 191-205 (Pubitemid 46209847)
    • (2007) Cancer Cell , vol.11 , Issue.2 , pp. 191-205
    • Dolado, I.1    Swat, A.2    Ajenjo, N.3    De Vita, G.4    Cuadrado, A.5    Nebreda, A.R.6
  • 16
    • 52049111663 scopus 로고    scopus 로고
    • TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-β
    • Yamashita, M., Fatyol, K., Jin, C., Wang, X., Liu, Z. and Zhang, Y.E. (2008) TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-β. Mol. Cell 31, 918-924
    • (2008) Mol. Cell , vol.31 , pp. 918-924
    • Yamashita, M.1    Fatyol, K.2    Jin, C.3    Wang, X.4    Liu, Z.5    Zhang, Y.E.6
  • 17
    • 79955852383 scopus 로고    scopus 로고
    • Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells
    • Taylor, M.A., Amin, J.D., Kirschmann, D.A. and Schiemann, W.P. (2011) Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells. Neoplasia 13, 406-418
    • (2011) Neoplasia , vol.13 , pp. 406-418
    • Taylor, M.A.1    Amin, J.D.2    Kirschmann, D.A.3    Schiemann, W.P.4
  • 19
    • 49649124944 scopus 로고    scopus 로고
    • Snail up-regulates proinflammatory mediators and inhibits differentiation in oral keratinocytes
    • Lyons, J.G., Patel, V., Roue, N.C., Fok, S.Y., Soon, L.L., Halliday, G.M. and Gutkind, J.S. (2008) Snail up-regulates proinflammatory mediators and inhibits differentiation in oral keratinocytes. Cancer Res. 68, 4525-4530
    • (2008) Cancer Res. , vol.68 , pp. 4525-4530
    • Lyons, J.G.1    Patel, V.2    Roue, N.C.3    Fok, S.Y.4    Soon, L.L.5    Halliday, G.M.6    Gutkind, J.S.7
  • 20
    • 0142026209 scopus 로고    scopus 로고
    • P38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
    • Kumar, S., Boehm, J. and Lee, J.C. (2003) p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat. Rev. Drug Discovery 2, 717-726 (Pubitemid 37361787)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.9 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3
  • 21
    • 0033166416 scopus 로고    scopus 로고
    • Stress activated protein kinase p38 is involved in IL-6 induced transcriptional activation of STAT3
    • DOI 10.1038/sj.onc.1202738
    • Zauberman, A., Zipori, D., Krupsky, M. and Ben-Levy, R. (1999) Stress activated protein kinase p38 is involved in IL-6 induced transcriptional activation of STAT3. Oncogene 18, 3886-3893 (Pubitemid 29358567)
    • (1999) Oncogene , vol.18 , Issue.26 , pp. 3886-3893
    • Zauberman, A.1    Zipori, D.2    Krupsky, M.3    Ben-Levy, R.4
  • 22
    • 20344386238 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling
    • DOI 10.1128/MCB.25.12.4853-4862.2005
    • Emerling, B.M., Platanias, L.C., Black, E., Nebreda, A.R., Davis, R.J. and Chandel, N.S. (2005) Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling. Mol. Cell. Biol. 25, 4853-4862 (Pubitemid 40781087)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.12 , pp. 4853-4862
    • Emerling, B.M.1    Platanias, L.C.2    Black, E.3    Nebreda, A.R.4    Davis, R.J.5    Chandel, N.S.6
  • 23
    • 70450142560 scopus 로고    scopus 로고
    • Inflammation and EMT: An alliance towards organ fibrosis and cancer progression
    • Lopez-Novoa, J.M. and Nieto, M.A. (2009) Inflammation and EMT: an alliance towards organ fibrosis and cancer progression. EMBO Mol. Med. 1, 303-314
    • (2009) EMBO Mol. Med. , vol.1 , pp. 303-314
    • Lopez-Novoa, J.M.1    Nieto, M.A.2
  • 25
    • 0035823598 scopus 로고    scopus 로고
    • Transendothelial migration of colon carcinoma cells requires expression of E-selectin by endothelial cells and activation of stress-activated protein kinase-2 (SAPK2/p38) in the tumor cells
    • Laferriere, J., Houle, F., Taher, M.M., Valerie, K. and Huot, J. (2001) Transendothelial migration of colon carcinoma cells requires expression of E-selectin by endothelial cells and activation of stress-activated protein kinase-2 (SAPK2/p38) in the tumor cells. J. Biol. Chem. 276, 33762-33772
    • (2001) J. Biol. Chem. , vol.276 , pp. 33762-33772
    • Laferriere, J.1    Houle, F.2    Taher, M.M.3    Valerie, K.4    Huot, J.5
  • 27
    • 33644508365 scopus 로고    scopus 로고
    • MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration
    • DOI 10.1038/sj.emboj.7600973, PII 7600973
    • Kobayashi, M., Nishita, M., Mishima, T., Ohashi, K. and Mizuno, K. (2006) MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration. EMBO J. 25, 713-726 (Pubitemid 43292434)
    • (2006) EMBO Journal , vol.25 , Issue.4 , pp. 713-726
    • Kobayashi, M.1    Nishita, M.2    Mishima, T.3    Ohashi, K.4    Mizuno, K.5
  • 28
    • 0037192458 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibitors and cancer: Trials and tribulations
    • DOI 10.1126/science.1067100
    • Coussens, L.M., Fingleton, B. and Matrisian, L.M. (2002) Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295, 2387-2392 (Pubitemid 34270240)
    • (2002) Science , vol.295 , Issue.5564 , pp. 2387-2392
    • Coussens, L.M.1    Fingleton, B.2    Matrisian, L.M.3
  • 29
    • 77953028343 scopus 로고    scopus 로고
    • Carbonic anhydrase XII promotes invasion and migration ability of MDA-MB-231 breast cancer cells through the p38 MAPK signaling pathway
    • Hsieh, M.J., Chen, K.S., Chiou, H.L. and Hsieh, Y.S. (2010) Carbonic anhydrase XII promotes invasion and migration ability of MDA-MB-231 breast cancer cells through the p38 MAPK signaling pathway. Eur. J. Cell Biol. 89, 598-606
    • (2010) Eur. J. Cell Biol. , vol.89 , pp. 598-606
    • Hsieh, M.J.1    Chen, K.S.2    Chiou, H.L.3    Hsieh, Y.S.4
  • 30
    • 0033981730 scopus 로고    scopus 로고
    • Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase
    • Johansson, N., Ala-aho, R., Uitto, V., Grénman, R., Fusenig, N.E., López-Otín, C. and Kähäri, V.M. (2000) Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase. J. Cell Sci. 113, 227-235 (Pubitemid 30088968)
    • (2000) Journal of Cell Science , vol.113 , Issue.2 , pp. 227-235
    • Johansson, N.1    Ala-aho, R.2    Uitto, V.-J.3    Grenman, R.4    Fusenig, N.E.5    Lopez-Otin, C.6    Kahari, V.-M.7
  • 31
    • 77955098807 scopus 로고    scopus 로고
    • Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis
    • Kumar, P., Yadav, A., Patel, S.N., Islam, M., Pan, Q., Merajver, S.D. and Teknos, T.N. (2010) Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis. Mol. Cancer 9, 206
    • (2010) Mol. Cancer , vol.9 , pp. 206
    • Kumar, P.1    Yadav, A.2    Patel, S.N.3    Islam, M.4    Pan, Q.5    Merajver, S.D.6    Teknos, T.N.7
  • 32
    • 79952745018 scopus 로고    scopus 로고
    • Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression
    • Park, S.Y., Jeong, K.J., Panupinthu, N., Yu, S., Lee, J., Han, J.W., Kim, J.M., Lee, J.S., Kang, J., Park, C.G. et al. (2011) Lysophosphatidic acid augments human hepatocellular carcinoma cell invasion through LPA1 receptor and MMP-9 expression. Oncogene 30, 1351-1359
    • (2011) Oncogene , vol.30 , pp. 1351-1359
    • Park, S.Y.1    Jeong, K.J.2    Panupinthu, N.3    Yu, S.4    Lee, J.5    Han, J.W.6    Kim, J.M.7    Lee, J.S.8    Kang, J.9    Park, C.G.10
  • 33
    • 33646859435 scopus 로고    scopus 로고
    • MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer
    • DOI 10.1038/sj.onc.1209337, PII 1209337
    • Xu, L., Chen, S. and Bergan, R.C. (2006) MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer. Oncogene 25, 2987-2998 (Pubitemid 43780463)
    • (2006) Oncogene , vol.25 , Issue.21 , pp. 2987-2998
    • Xu, L.1    Chen, S.2    Bergan, R.C.3
  • 35
    • 0034697159 scopus 로고    scopus 로고
    • Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38α mitogen-activated protein kinase activity
    • DOI 10.1074/jbc.275.16.12266
    • Huang, S., New, L., Pan, Z., Han, J. and Nemerow, G.R. (2000) Urokinase plasminogen activator/urokinase-specific surface receptor expression and matrix invasion by breast cancer cells requires constitutive p38αmitogen- activated protein kinase activity. J. Biol. Chem. 275, 12266-12272 (Pubitemid 30237807)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.16 , pp. 12266-12272
    • Huang, S.1    New, L.2    Pan, Z.3    Han, J.4    Nemerow, G.R.5
  • 36
    • 0036906177 scopus 로고    scopus 로고
    • uPAR: A versatile signalling orchestrator
    • DOI 10.1038/nrm977
    • Blasi, F. and Carmeliet, P. (2002) uPAR: a versatile signalling orchestrator. Nat. Rev. Mol. Cell Biol. 3, 932-943 (Pubitemid 35477371)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.12 , pp. 932-943
    • Blasi, F.1    Carmeliet, P.2
  • 37
    • 77950828060 scopus 로고    scopus 로고
    • Phospholipase A2 activity of peroxiredoxin 6 promotes invasion and metastasis of lung cancer cells
    • Ho, J.N., Lee, S.B., Lee, S.S., Yoon, S.H., Kang, G.Y., Hwang, S.G. and Um, H.D. (2010) Phospholipase A2 activity of peroxiredoxin 6 promotes invasion and metastasis of lung cancer cells. Mol. Cancer Ther. 9, 825-832
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 825-832
    • Ho, J.N.1    Lee, S.B.2    Lee, S.S.3    Yoon, S.H.4    Kang, G.Y.5    Hwang, S.G.6    Um, H.D.7
  • 38
    • 78649501379 scopus 로고    scopus 로고
    • Integrin β3 and its ligand regulate the expression of uPA through p38 MAPK in breast cancer
    • Wang, R., Li, Z.Q., Han, X., Li, B.L., Mi, X.Y., Sun, L.M., Song, M., Han, Y.C., Zhao, Y. and Wang, E.H. (2010) Integrin β3 and its ligand regulate the expression of uPA through p38 MAPK in breast cancer. APMIS 118, 909-917
    • (2010) APMIS , vol.118 , pp. 909-917
    • Wang, R.1    Li, Z.Q.2    Han, X.3    Li, B.L.4    Mi, X.Y.5    Sun, L.M.6    Song, M.7    Han, Y.C.8    Zhao, Y.9    Wang, E.H.10
  • 39
    • 33646361573 scopus 로고    scopus 로고
    • Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38
    • DOI 10.1016/j.cellsig.2005.09.004, PII S0898656805002391
    • Dreissigacker, U., Mueller, M.S., Unger, M., Siegert, P., Genze, F., Gierschik, P. and Giehl, K. (2006) Oncogenic K-Ras down-regulates Rac1 and RhoA activity and enhances migration and invasion of pancreatic carcinoma cells through activation of p38. Cell. Signalling 18, 1156-1168 (Pubitemid 43674042)
    • (2006) Cellular Signalling , vol.18 , Issue.8 , pp. 1156-1168
    • Dreissigacker, U.1    Mueller, M.S.2    Unger, M.3    Siegert, P.4    Genze, F.5    Gierschik, P.6    Giehl, K.7
  • 40
    • 34249314755 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase pathway is involved in protein kinase Cα-regulated invasion in human hepatocellular carcinoma cells
    • Hsieh, Y.H., Wu, T.T., Huang, C.Y., Hsieh, Y.S., Hwang, J.M. and Liu, J.Y. (2007) p38 mitogen-activated protein kinase pathway is involved in protein kinase Cα-regulated invasion in human hepatocellular carcinoma cells. Cancer Res. 67, 4320-4327
    • (2007) Cancer Res. , vol.67 , pp. 4320-4327
    • Hsieh, Y.H.1    Wu, T.T.2    Huang, C.Y.3    Hsieh, Y.S.4    Hwang, J.M.5    Liu, J.Y.6
  • 41
    • 34547809513 scopus 로고    scopus 로고
    • p38α and p38δ mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells
    • DOI 10.1038/sj.onc.1210332, PII 1210332
    • Junttila, M.R., Ala-Aho, R., Jokilehto, T., Peltonen, J., Kallajoki, M., Grenman, R., Jaakkola, P., Westermarck, J. and Kahari, V.M. (2007) p38αand p38δ mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells. Oncogene 26, 5267-5279 (Pubitemid 47237627)
    • (2007) Oncogene , vol.26 , Issue.36 , pp. 5267-5279
    • Junttila, M.R.1    Ala-Aho, R.2    Jokilehto, T.3    Peltonen, J.4    Kallajoki, M.5    Grenman, R.6    Jaakkola, P.7    Westermarck, J.8    Kahari, V.-M.9
  • 43
    • 77949424255 scopus 로고    scopus 로고
    • Phenotype-assisted transcriptome analysis identifies FOXM1 downstream from Ras-MKK3-p38 to regulate in vitro cellular invasion
    • Behren, A., Muhlen, S., Acuna Sanhueza, G.A., Schwager, C., Plinkert, P.K., Huber, P.E., Abdollahi, A. and Simon, C. (2010) Phenotype-assisted transcriptome analysis identifies FOXM1 downstream from Ras-MKK3-p38 to regulate in vitro cellular invasion. Oncogene 29, 1519-1530
    • (2010) Oncogene , vol.29 , pp. 1519-1530
    • Behren, A.1    Muhlen, S.2    Acuna Sanhueza, G.A.3    Schwager, C.4    Plinkert, P.K.5    Huber, P.E.6    Abdollahi, A.7    Simon, C.8
  • 45
    • 79955819010 scopus 로고    scopus 로고
    • p38γ mitogen-activated protein kinase contributes to oncogenic properties maintenance and resistance to poly (ADP-ribose)-polymerase-1 inhibition in breast cancer
    • Meng, F., Zhang, H., Liu, G., Kreike, B., Chen, W., Sethi, S., Miller, F.R. and Wu, G. (2011) p38γ mitogen-activated protein kinase contributes to oncogenic properties maintenance and resistance to poly (ADP-ribose)- polymerase-1 inhibition in breast cancer. Neoplasia 13, 472-482
    • (2011) Neoplasia , vol.13 , pp. 472-482
    • Meng, F.1    Zhang, H.2    Liu, G.3    Kreike, B.4    Chen, W.5    Sethi, S.6    Miller, F.R.7    Wu, G.8
  • 50
    • 67649675530 scopus 로고    scopus 로고
    • Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling
    • Zhang, Y., Rivera Rosado, L.A., Moon, S.Y. and Zhang, B. (2009) Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling. J. Biol. Chem. 284, 12956-12965
    • (2009) J. Biol. Chem. , vol.284 , pp. 12956-12965
    • Zhang, Y.1    Rivera Rosado, L.A.2    Moon, S.Y.3    Zhang, B.4
  • 52
    • 33749485053 scopus 로고    scopus 로고
    • Regulation of transendothelial migration of colon cancer cells by E-selectin-mediated activation of p38 and ERK MAP kinases
    • DOI 10.1038/sj.onc.1209664, PII 1209664
    • Tremblay, P.L., Auger, F.A. and Huot, J. (2006) Regulation of transendothelial migration of colon cancer cells by E-selectin-mediated activation of p38 and ERK MAP kinases. Oncogene 25, 6563-6573 (Pubitemid 44646184)
    • (2006) Oncogene , vol.25 , Issue.50 , pp. 6563-6573
    • Tremblay, P.-L.1    Auger, F.A.2    Huot, J.3
  • 55
    • 33751504690 scopus 로고    scopus 로고
    • Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis
    • DOI 10.1038/ncb1507, PII NCB1507
    • Hiratsuka, S., Watanabe, A., Aburatani, H. and Maru, Y. (2006) Tumourmediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat. Cell Biol. 8, 1369-1375 (Pubitemid 44835111)
    • (2006) Nature Cell Biology , vol.8 , Issue.12 , pp. 1369-1375
    • Hiratsuka, S.1    Watanabe, A.2    Aburatani, H.3    Maru, Y.4
  • 56
    • 78651109040 scopus 로고    scopus 로고
    • C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells
    • Hiratsuka, S., Duda, D.G., Huang, Y., Goel, S., Sugiyama, T., Nagasawa, T., Fukumura, D. and Jain, R.K. (2011) C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells. Proc. Natl. Acad. Sci. U.S.A. 108, 302-307
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 302-307
    • Hiratsuka, S.1    Duda, D.G.2    Huang, Y.3    Goel, S.4    Sugiyama, T.5    Nagasawa, T.6    Fukumura, D.7    Jain, R.K.8
  • 57
    • 0034447622 scopus 로고    scopus 로고
    • Integrating the VEGF signals leading to actin-based motility in vascular endothelial cells
    • DOI 10.1016/S1050-1738(01)00072-X, PII S105017380100072X
    • Rousseau, S., Houle, F. and Huot, J. (2000) Integrating the VEGF signals leading to actin-based motility in vascular endothelial cells. Trends Cardiovasc. Med. 10, 321-327 (Pubitemid 32448042)
    • (2000) Trends in Cardiovascular Medicine , vol.10 , Issue.8 , pp. 321-327
    • Rousseau, S.1    Houle, F.2    Huot, J.3
  • 58
    • 20444385832 scopus 로고    scopus 로고
    • Activation of p38 has opposing effects on the proliferation and migration of endothelial cells
    • DOI 10.1074/jbc.M407060200
    • McMullen, M.E., Bryant, P.W., Glembotski, C.C., Vincent, P.A. and Pumiglia, K.M. (2005) Activation of p38 has opposing effects on the proliferation and migration of endothelial cells. J. Biol. Chem. 280, 20995-21003 (Pubitemid 40805657)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.22 , pp. 20995-21003
    • McMullen, M.E.1    Bryant, P.W.2    Glembotski, C.C.3    Vincent, P.A.4    Pumiglia, K.M.5
  • 59
    • 57849100048 scopus 로고    scopus 로고
    • Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
    • Erler, J.T., Bennewith, K.L., Cox, T.R., Lang, G., Bird, D., Koong, A., Le, Q.T. and Giaccia, A.J. (2009) Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 15, 35-44
    • (2009) Cancer Cell , vol.15 , pp. 35-44
    • Erler, J.T.1    Bennewith, K.L.2    Cox, T.R.3    Lang, G.4    Bird, D.5    Koong, A.6    Le, Q.T.7    Giaccia, A.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.