-
1
-
-
0031866431
-
A combination of NaCl and urea enhances survival of IMCD cells to hyperosmolality
-
Santos BC, Chevaile A, Hebert MJ, Zagajeski J, Gullans SR (1998) A combination of NaCl and urea enhances survival of IMCD cells to hyperosmolality. Am J Physiol 274:F1167-F1173.
-
(1998)
Am J Physiol
, vol.274
-
-
Santos, B.C.1
Chevaile, A.2
Hebert, M.J.3
Zagajeski, J.4
Gullans, S.R.5
-
2
-
-
0034055321
-
Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells
-
Michea L, et al. (2000) Cell cycle delay and apoptosis are induced by high salt and urea in renal medullary cells. Am J Physiol 278:F209-F218.
-
(2000)
Am J Physiol
, vol.278
-
-
Michea, L.1
-
3
-
-
3042546084
-
High urea and NaCl carbonylate proteins in renal cells in culture and in vivo, and high urea causes 8-oxoguanine lesions in their DNA
-
Zhang Z, Dmitrieva NI, Park JH, Levine RL, Burg MB (2004) High urea and NaCl carbonylate proteins in renal cells in culture and in vivo, and high urea causes 8-oxoguanine lesions in their DNA. Proc Natl Acad Sci USA 101:9491-9496.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 9491-9496
-
-
Zhang, Z.1
Dmitrieva, N.I.2
Park, J.H.3
Levine, R.L.4
Burg, M.B.5
-
4
-
-
0035852695
-
Hyperosmolality in the form of elevated NaCl but not urea causes DNA damage in murine kidney cells
-
Kultz D, Chakravarty D (2001) Hyperosmolality in the form of elevated NaCl but not urea causes DNA damage in murine kidney cells. Proc Natl Acad Sci USA 98:1999-2004.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1999-2004
-
-
Kultz, D.1
Chakravarty, D.2
-
5
-
-
0037484458
-
High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair
-
Dmitrieva NI, Bulavin DV, Burg MB (2003) High NaCl causes Mre11 to leave the nucleus, disrupting DNA damage signaling and repair. Am J Physiol 285:F266-F274.
-
(2003)
Am J Physiol
, vol.285
-
-
Dmitrieva, N.I.1
Bulavin, D.V.2
Burg, M.B.3
-
7
-
-
4644333445
-
Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression
-
Lopez-Rodriguez C, et al. (2004) Loss of NFAT5 results in renal atrophy and lack of tonicity-responsive gene expression. Proc Natl Acad Sci USA 101:2392-2397.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2392-2397
-
-
Lopez-Rodriguez, C.1
-
8
-
-
0037195922
-
Fyn and p38 signaling are both required for maximal hypertonic activation of the OREBP/TonEBP
-
Ko BC, et al. (2002) Fyn and p38 signaling are both required for maximal hypertonic activation of the OREBP/TonEBP. J Biol Chem 277:46085-46092.
-
(2002)
J Biol Chem
, vol.277
, pp. 46085-46092
-
-
Ko, B.C.1
-
9
-
-
0033575281
-
Osmotic response element enhancer activity: Regulation through p38 kinase and mitogen-activated extracellular signal-regulated kinase kinase
-
Nadkarni V, Gabbay KH, Bohren KM, Sheikh-Hamad D (1999) Osmotic response element enhancer activity: Regulation through p38 kinase and mitogen-activated extracellular signal-regulated kinase kinase. J Biol Chem 274:20185-20190.
-
(1999)
J Biol Chem
, vol.274
, pp. 20185-20190
-
-
Nadkarni, V.1
Gabbay, K.H.2
Bohren, K.M.3
Sheikh-Hamad, D.4
-
10
-
-
33749407195
-
MEKK3-mediated signaling to p38 kinase and TonE in hypertonically stressed kidney cells
-
Padda R, et al. (2006) MEKK3-mediated signaling to p38 kinase and TonE in hypertonically stressed kidney cells. Am J Physiol 291:F874-F881.
-
(2006)
Am J Physiol
, vol.291
-
-
Padda, R.1
-
11
-
-
0036683337
-
Yeast go the whole HOG for the hyperosmotic response
-
O'Rourke SM, Herskowitz I, O'Shea EK (2002) Yeast go the whole HOG for the hyperosmotic response. Trends Genet 18:405-412.
-
(2002)
Trends Genet
, vol.18
, pp. 405-412
-
-
O'Rourke, S.M.1
Herskowitz, I.2
O'Shea, E.K.3
-
12
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han J, Lee JD, Bibbs L, Ulevitch RJ (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265:808-811.
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.D.2
Bibbs, L.3
Ulevitch, R.J.4
-
13
-
-
0344668554
-
Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock
-
Uhlik MT, et al. (2003) Rac-MEKK3-MKK3 scaffolding for p38 MAPK activation during hyperosmotic shock. Nat Cell Biol 5:1104-1110.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 1104-1110
-
-
Uhlik, M.T.1
-
14
-
-
18144384775
-
Essential role for mitogen-activated protein (MAP) kinase phosphatase-1 in stress-responsive MAP kinase and cell survival signaling
-
Wu JJ, Bennett AM (2005) Essential role for mitogen-activated protein (MAP) kinase phosphatase-1 in stress-responsive MAP kinase and cell survival signaling. J Biol Chem 280:16461-16466.
-
(2005)
J Biol Chem
, vol.280
, pp. 16461-16466
-
-
Wu, J.J.1
Bennett, A.M.2
-
15
-
-
0040826869
-
Distinct regulation of osmoprotective genes in yeast and mammals: Aldose reductase osmotic response element is induced independent of p38 and stress-activated protein kinase/Jun N-terminal kinase in rabbit kidney cells
-
Kultz D, Garcia-Perez A, Ferraris JD, Burg MB (1997) Distinct regulation of osmoprotective genes in yeast and mammals: Aldose reductase osmotic response element is induced independent of p38 and stress-activated protein kinase/Jun N-terminal kinase in rabbit kidney cells. J Biol Chem 272:13165-13170.
-
(1997)
J Biol Chem
, vol.272
, pp. 13165-13170
-
-
Kultz, D.1
Garcia-Perez, A.2
Ferraris, J.D.3
Burg, M.B.4
-
16
-
-
0030828701
-
Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38d
-
Jiang Y, et al. (1997) Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38d. J Biol Chem 272:30122-30128.
-
(1997)
J Biol Chem
, vol.272
, pp. 30122-30128
-
-
Jiang, Y.1
-
17
-
-
0346096918
-
Effects of p38MAPK isoforms on renal mesangial cell inducible nitric oxide synthase expression
-
Lui P, et al. (2004) Effects of p38MAPK isoforms on renal mesangial cell inducible nitric oxide synthase expression. Am J Physiol 286:C145-C152.
-
(2004)
Am J Physiol
, vol.286
-
-
Lui, P.1
-
18
-
-
33846839324
-
Intrinsically active variants of all human p38 isoforms
-
Avitzour M, et al. (2007) Intrinsically active variants of all human p38 isoforms. FEBS J 274:963-975.
-
(2007)
FEBS J
, vol.274
, pp. 963-975
-
-
Avitzour, M.1
-
19
-
-
22344443038
-
Increased reactive oxygen species contribute to high NaCl-induced activation of the osmoregulatory transcription factor TonEBP/OREBP
-
Zhou X, Ferraris JD, Cai Q, Agarwal A, Burg MB (2005) Increased reactive oxygen species contribute to high NaCl-induced activation of the osmoregulatory transcription factor TonEBP/OREBP. Am J Physiol 289:F377-F385.
-
(2005)
Am J Physiol
, vol.289
-
-
Zhou, X.1
Ferraris, J.D.2
Cai, Q.3
Agarwal, A.4
Burg, M.B.5
-
20
-
-
14844327760
-
Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
Kamata H, et al (2005) Reactive oxygen species promote TNFα-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120:649-661.
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
-
21
-
-
27144524287
-
Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin
-
Yang T, et al. (2005) Hypertonic induction of COX-2 in collecting duct cells by reactive oxygen species of mitochondrial origin. J Biol Chem 280:34966-34973.
-
(2005)
J Biol Chem
, vol.280
, pp. 34966-34973
-
-
Yang, T.1
-
22
-
-
0033559005
-
Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture
-
Robinson KA, et al. (1999) Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture. J Neurosci Res 55:724-732.
-
(1999)
J Neurosci Res
, vol.55
, pp. 724-732
-
-
Robinson, K.A.1
-
23
-
-
0037507258
-
Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene
-
Umenishi F, Schrier RW (2003) Hypertonicity-induced aquaporin-1 (AQP1) expression is mediated by the activation of MAPK pathways and hypertonicity-responsive element in the AQP1 gene. J Biol Chem 278:15765-15770.
-
(2003)
J Biol Chem
, vol.278
, pp. 15765-15770
-
-
Umenishi, F.1
Schrier, R.W.2
-
24
-
-
0035145860
-
N-acetylcysteine attenuates TNF-α-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells
-
Hashimoto S, Gon Y, Matsumoto K, Takeshita I, Horie T (2001) N-acetylcysteine attenuates TNF-α-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells. Br J Pharmacol 132:270-276.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 270-276
-
-
Hashimoto, S.1
Gon, Y.2
Matsumoto, K.3
Takeshita, I.4
Horie, T.5
-
25
-
-
0034668924
-
Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: Critical role of the p38 C-terminal domain in its negative regulation
-
Hutter D, Chen P, Barnes J, Liu Y (2000) Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: Critical role of the p38 C-terminal domain in its negative regulation. Biochem J 352:155-163.
-
(2000)
Biochem J
, vol.352
, pp. 155-163
-
-
Hutter, D.1
Chen, P.2
Barnes, J.3
Liu, Y.4
-
26
-
-
0035844140
-
Distinct binding determinants for ERK2/p38α and JNK MAP kinases mediate catalytic activation and substrate selectivity of MAP kinase phosphatase-1
-
Slack DN, Seternes OM, Gabrielsen M, Keyse SM (2001) Distinct binding determinants for ERK2/p38α and JNK MAP kinases mediate catalytic activation and substrate selectivity of MAP kinase phosphatase-1. J Biol Chem 276:16491-16500.
-
(2001)
J Biol Chem
, vol.276
, pp. 16491-16500
-
-
Slack, D.N.1
Seternes, O.M.2
Gabrielsen, M.3
Keyse, S.M.4
-
27
-
-
0034096201
-
Protein phosphatases and the regulation of mitogen-activated protein kinase signaling
-
Keyse SM (2000) Protein phosphatases and the regulation of mitogen-activated protein kinase signaling. Curr Opin Cell Biol 12:186-192.
-
(2000)
Curr Opin Cell Biol
, vol.12
, pp. 186-192
-
-
Keyse, S.M.1
-
28
-
-
34249665604
-
Regulation of innate immune response by MAP kinase phosphatase-1
-
Wang X, Liu Y (2007) Regulation of innate immune response by MAP kinase phosphatase-1. Cell Signal 19:1372-1382.
-
(2007)
Cell Signal
, vol.19
, pp. 1372-1382
-
-
Wang, X.1
Liu, Y.2
-
29
-
-
0031916832
-
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6
-
Enslen H, Raingeaud J, Davis RJ (1998) Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J Biol Chem 273:1741-1748.
-
(1998)
J Biol Chem
, vol.273
, pp. 1741-1748
-
-
Enslen, H.1
Raingeaud, J.2
Davis, R.J.3
-
30
-
-
0027525215
-
An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse
-
Rauchman MI, Nigam SK, Delpire E, Gullans SR (1993) An osmotically tolerant inner medullary collecting duct cell line from an SV40 transgenic mouse. Am J Physiol 265:F416-F424.
-
(1993)
Am J Physiol
, vol.265
-
-
Rauchman, M.I.1
Nigam, S.K.2
Delpire, E.3
Gullans, S.R.4
-
31
-
-
0036451717
-
A mammalian expression system for rapid production and purification of active MAP kinase phosphatases
-
Chen P, Hutter D, Liu P, Liu Y (2002) A mammalian expression system for rapid production and purification of active MAP kinase phosphatases. Protein Expression Purif 24:481-488.
-
(2002)
Protein Expression Purif
, vol.24
, pp. 481-488
-
-
Chen, P.1
Hutter, D.2
Liu, P.3
Liu, Y.4
-
32
-
-
0037036460
-
Redox regulation of Cdc25C
-
Savitsky PA, Finkel T (2002) Redox regulation of Cdc25C. J Biol Chem 277:20535-20540.
-
(2002)
J Biol Chem
, vol.277
, pp. 20535-20540
-
-
Savitsky, P.A.1
Finkel, T.2
-
33
-
-
33745035164
-
Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation
-
Irarrazabal CE, Burg MB, Ward SG, Ferraris JD (2006) Phosphatidylinositol 3-kinase mediates activation of ATM by high NaCl and by ionizing radiation: Role in osmoprotective transcriptional regulation. Proc Natl Acad Sci USA 103:8882-8887.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8882-8887
-
-
Irarrazabal, C.E.1
Burg, M.B.2
Ward, S.G.3
Ferraris, J.D.4
-
34
-
-
1442354963
-
Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo
-
Dmitrieva NI, Cai Q, Burg MB (2004) Cells adapted to high NaCl have many DNA breaks and impaired DNA repair both in cell culture and in vivo. Proc Natl Acad Sci USA 101:2317-2322.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2317-2322
-
-
Dmitrieva, N.I.1
Cai, Q.2
Burg, M.B.3
-
35
-
-
33646595343
-
Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP
-
Zhou X, Ferraris JD, Burg MB (2006) Mitochondrial reactive oxygen species contribute to high NaCl-induced activation of the transcription factor TonEBP/OREBP. Am J Physiol 290:F1169-F1176.
-
(2006)
Am J Physiol
, vol.290
-
-
Zhou, X.1
Ferraris, J.D.2
Burg, M.B.3
-
36
-
-
0031471026
-
A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side-chain variation
-
Rice RL, et al. (1997) A targeted library of small-molecule, tyrosine, and dual-specificity phosphatase inhibitors derived from a rational core design and random side-chain variation. Biochemistry 36:15965-15974.
-
(1997)
Biochemistry
, vol.36
, pp. 15965-15974
-
-
Rice, R.L.1
|