-
1
-
-
70449532454
-
Selenoprotein W modulates control of cell cycle entry
-
Hawkes, W. C., Wang, T. T., Alkan, Z., Richter, B. D., and Dawson, K. (2009) Selenoprotein W modulates control of cell cycle entry. Biol. Trace Elem. Res. 131, 229-244
-
(2009)
Biol. Trace Elem. Res.
, vol.131
, pp. 229-244
-
-
Hawkes, W.C.1
Wang, T.T.2
Alkan, Z.3
Richter, B.D.4
Dawson, K.5
-
2
-
-
80052849822
-
Delayed cell cycle progression from SEPW1 depletion is p53- And p21-dependent in MCF-7 breast cancer cells
-
Hawkes, W. C., and Alkan, Z. (2011) Delayed cell cycle progression from SEPW1 depletion is p53- and p21-dependent in MCF-7 breast cancer cells. Biochem. Biophys. Res. Commun. 413, 36-40
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.413
, pp. 36-40
-
-
Hawkes, W.C.1
Alkan, Z.2
-
3
-
-
84055222667
-
Selenoprotein W depletion induces a p53- And p21-dependent delay in cell cycle progression in RWPE-1 prostate epithelial cells
-
Hawkes, W. C., Printsev, I., and Alkan, Z. (2012) Selenoprotein W depletion induces a p53- and p21-dependent delay in cell cycle progression in RWPE-1 prostate epithelial cells. J. Cell Biochem. 113, 61-69
-
(2012)
J. Cell Biochem.
, vol.113
, pp. 61-69
-
-
Hawkes, W.C.1
Printsev, I.2
Alkan, Z.3
-
4
-
-
4444240191
-
The functional interactions between the p53 and MAPK signaling pathways
-
Wu, G. S. (2004) The functional interactions between the p53 and MAPK signaling pathways. Cancer Biol. Ther. 3, 156-161
-
(2004)
Cancer Biol. Ther.
, vol.3
, pp. 156-161
-
-
Wu, G.S.1
-
5
-
-
34248597048
-
Role of mitogen-activated protein kinase kinase 4 in cancer
-
DOI 10.1038/sj.onc.1210410, PII 1210410
-
Whitmarsh, A. J., and Davis, R. J. (2007) Role of mitogen-activated protein kinase kinase 4 in cancer. Oncogene 26, 3172-3184 (Pubitemid 46763013)
-
(2007)
Oncogene
, vol.26
, Issue.22
, pp. 3172-3184
-
-
Whitmarsh, A.J.1
Davis, R.J.2
-
6
-
-
0030059508
-
Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase
-
Salmeron, A., Ahmad, T. B., Carlile, G. W., Pappin, D., Narsimhan, R. P., and Ley, S. C. (1996) Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase. EMBO J. 15, 817-826
-
(1996)
EMBO J
, vol.15
, pp. 817-826
-
-
Salmeron, A.1
Ahmad, T.B.2
Carlile, G.W.3
Pappin, D.4
Narsimhan, R.P.5
Ley, S.C.6
-
7
-
-
0034737642
-
Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells
-
DOI 10.1074/jbc.275.13.9805
-
Takeda, K., Hatai, T., Hamazaki, T. S., Nishitoh, H., Saitoh, M., and Ichijo, H. (2000) Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells. J. Biol. Chem. 275, 9805-9813 (Pubitemid 30185216)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.13
, pp. 9805-9813
-
-
Takeda, K.1
Hatai, T.2
Hamazaki, T.S.3
Nishitoh, H.4
Saitoh, M.5
Ichijo, H.6
-
8
-
-
82255186525
-
MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression
-
Szmulewitz, R. Z., Clark, R., Lotan, T., Otto, K., Taylor Veneris, J., Macleod, K., and Rinker-Schaeffer, C. (2012) MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression. Int. J. Cancer 130, 509-520
-
(2012)
Int. J. Cancer
, vol.130
, pp. 509-520
-
-
Szmulewitz, R.Z.1
Clark, R.2
Lotan, T.3
Otto, K.4
Taylor Veneris, J.5
Macleod, K.6
Rinker-Schaeffer, C.7
-
9
-
-
17344375955
-
SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development
-
DOI 10.1016/S1074-7613(00)80567-1
-
Swat, W., Fujikawa, K., Ganiatsas, S., Yang, D., Xavier, R. J., Harris, N. L., Davidson, L., Ferrini, R., Davis, R. J., Labow, M. A., Flavell, R. A., Zon, L. I., and Alt, F. W. (1998) SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development. Immunity 8, 625-634 (Pubitemid 28264753)
-
(1998)
Immunity
, vol.8
, Issue.5
, pp. 625-634
-
-
Swat, W.1
Fujikawa, K.2
Ganiatsas, S.3
Yang, D.4
Xavier, R.J.5
Harris, N.L.6
Davidson, L.7
Ferrini, R.8
Davis, R.J.9
Labow, M.A.10
Flavell, R.A.11
Zon, L.I.12
Alt, F.W.13
-
10
-
-
0033063568
-
Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4
-
Nishina, H., Vaz, C., Billia, P., Nghiem, M., Sasaki, T., De la Pompa, J. L., Furlonger, K., Paige, C., Hui, C., Fischer, K. D., Kishimoto, H., Iwatsubo, T., Katada, T., Woodgett, J. R., and Penninger, J. M. (1999) Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4. Development 126, 505-516 (Pubitemid 29082037)
-
(1999)
Development
, vol.126
, Issue.3
, pp. 505-516
-
-
Nishina, H.1
Vaz, C.2
Billia, P.3
Nghiem, M.4
Sasaki, T.5
De La, P.J.L.6
Furlonger, K.7
Paige, C.8
Hui, C.-C.9
Fischer, K.-D.10
Kishimoto, H.11
Iwatsubo, T.12
Katada, T.13
Woodgett, J.R.14
Penninger, J.M.15
-
11
-
-
79952673049
-
MKK4 as oncogene or tumor suppressor. In cancer and senescence, the story's getting old
-
Cunningham, S. C., Gallmeier, E., and Kern, S. E. (2010) MKK4 as oncogene or tumor suppressor. In cancer and senescence, the story's getting old. Aging 2, 752-753
-
(2010)
Aging
, vol.2
, pp. 752-753
-
-
Cunningham, S.C.1
Gallmeier, E.2
Kern, S.E.3
-
13
-
-
0030693181
-
JNK1, JNK2 and JNK3 are p53 n-terminal serine 34 kinases
-
Hu, M. C., Qiu, W. R., and Wang, Y. P. (1997) JNK1, JNK2, and JNK3 are p53 N-terminal serine 34 kinases. Oncogene 15, 2277-2287 (Pubitemid 27496979)
-
(1997)
Oncogene
, vol.15
, Issue.19
, pp. 2277-2287
-
-
Hu, M.C.-T.1
Qiu, W.R.2
Wang, Y.-P.3
-
14
-
-
0035914446
-
Osmotic shock induces G1 arrest through p53 phosphorylation at Ser-33 by activated p38MAPK without phosphorylation at Ser-15 and Ser-20
-
Kishi, H., Nakagawa, K., Matsumoto, M., Suga, M., Ando, M., Taya, Y., and Yamaizumi, M. (2001) Osmotic shock induces G1 arrest through p53 phosphorylation at Ser-33 by activated p38MAPK without phosphorylation at Ser-15 and Ser-20. J. Biol. Chem. 276, 39115-39122
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39115-39122
-
-
Kishi, H.1
Nakagawa, K.2
Matsumoto, M.3
Suga, M.4
Ando, M.5
Taya, Y.6
Yamaizumi, M.7
-
15
-
-
0842269247
-
The importance of p53 location: Nuclear or cytoplasmic zip code?
-
DOI 10.1016/j.drup.2003.10.004
-
O'Brate, A., and Giannakakou, P. (2003) The importance of p53 location. Nuclear or cytoplasmic zip code? Drug Resist. Updat. 6, 313-322 (Pubitemid 38173582)
-
(2003)
Drug Resistance Updates
, vol.6
, Issue.6
, pp. 313-322
-
-
O'Brate, A.1
Giannakakou, P.2
-
16
-
-
34247128687
-
Regulation of the metastasis suppressor gene MKK4 in ovarian cancer
-
DOI 10.1016/j.ygyno.2006.12.017, PII S0090825806009735
-
Spillman, M. A., Lacy, J., Murphy, S. K., Whitaker, R. S., Grace, L., Teaberry, V., Marks, J. R., and Berchuck, A. (2007) Regulation of the metastasis suppressor gene MKK4 in ovarian cancer. Gynecol. Oncol. 105, 312-320 (Pubitemid 46590321)
-
(2007)
Gynecologic Oncology
, vol.105
, Issue.2
, pp. 312-320
-
-
Spillman, M.A.1
Lacy, J.2
Murphy, S.K.3
Whitaker, R.S.4
Grace, L.5
Teaberry, V.6
Marks, J.R.7
Berchuck, A.8
-
17
-
-
40949105944
-
2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines
-
DOI 10.1158/1541-7786.MCR-07-2075
-
Robinson, V. L., Shalhav, O., Otto, K., Kawai, T., Gorospe, M., and Rinker-Schaeffer, C. W. (2008) Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines. Mol. Cancer Res. 6, 501-508 (Pubitemid 351416540)
-
(2008)
Molecular Cancer Research
, vol.6
, Issue.3
, pp. 501-508
-
-
Robinson, V.L.1
Shalhav, O.2
Otto, K.3
Kawai, T.4
Gorospe, M.5
Rinker-Schaeffer, C.W.6
-
18
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis, R. J. (2000) Signal transduction by the JNK group of MAP kinases. Cell 103, 239-252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
19
-
-
21644462265
-
Cip1/Waf1 upregulation and endothelial apoptosis
-
DOI 10.1152/ajpheart.00901.2004
-
Nuntharatanapong, N., Chen, K., Sinhaseni, P., and Keaney, J. F., Jr. (2005) EGF receptor-dependent JNK activation is involved in arsenite-induced p21Cip1/Waf1 up-regulation and endothelial apoptosis. Am. J. Physiol. Heart Circ. Physiol. 289, H99-H107 (Pubitemid 40934087)
-
(2005)
American Journal of Physiology - Heart and Circulatory Physiology
, vol.289
, Issue.1
-
-
Nuntharatanapong, N.1
Chen, K.2
Sinhaseni, P.3
Keaney Jr., J.F.4
-
20
-
-
0032167915
-
MEKK1/JNK signaling stabilizes and activates p53
-
DOI 10.1073/pnas.95.18.10541
-
Fuchs, S. Y., Adler, V., Pincus, M. R., and Ronai, Z. (1998) MEKK1/JNK signaling stabilizes and activates p53. Proc. Natl. Acad. Sci. U.S.A. 95, 10541-10546 (Pubitemid 28413103)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.18
, pp. 10541-10546
-
-
Fuchs, S.Y.1
Adler, V.2
Pincus, M.R.3
Ronai, Z.4
-
21
-
-
0038351916
-
Ultraviolet light-induced apoptotic death is impaired by the HMG-CoA reductase inhibitor lovastatin
-
DOI 10.1016/S0006-291X(03)01205-1
-
Bardeleben, R., Kaina, B., and Fritz, G. (2003) Ultraviolet light-induced apoptotic death is impaired by the HMG-CoA reductase inhibitor lovastatin. Biochem. Biophys. Res. Commun. 307, 401-407 (Pubitemid 36818885)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.307
, Issue.2
, pp. 401-407
-
-
Bardeleben, R.V.1
Kaina, B.2
Fritz, G.3
-
22
-
-
0034194714
-
2-terminal kinase
-
DOI 10.1083/jcb.149.3.741
-
Almeida, E. A., Ili, D., Han, Q., Hauck, C. R., Jin, F., Kawakatsu, H., Schlaepfer, D. D., and Damsky, C. H. (2000) Matrix survival signaling. From fibronectin via focal adhesion kinase to c-Jun NH2-terminal kinase. J. Cell Biol. 149, 741-754 (Pubitemid 30252406)
-
(2000)
Journal of Cell Biology
, vol.149
, Issue.3
, pp. 741-754
-
-
Almeida, E.A.C.1
Ilic, D.2
Han, Q.3
Hauck, C.R.4
Jin, F.5
Kawakatsu, H.6
Schlaepfer, D.D.7
Damsky, C.H.8
-
23
-
-
12644257580
-
Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase
-
DOI 10.1073/pnas.94.18.9687
-
Diener, K., Wang, X. S., Chen, C., Meyer, C. F., Keesler, G., Zukowski, M., Tan, T. H., and Yao, Z. (1997) Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase. Proc. Natl. Acad. Sci. U.S.A. 94, 9687-9692 (Pubitemid 27408124)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.18
, pp. 9687-9692
-
-
Diener, K.1
Wang, X.S.2
Chen, C.3
Meyer, C.F.4
Keesler, G.5
Zukowski, M.6
Tan, T.-H.7
Yao, Z.8
-
24
-
-
34147186130
-
Apoptosis signal-regulating kinase (ASK) 2 functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1
-
DOI 10.1074/jbc.M607177200
-
Takeda, K., Shimozono, R., Noguchi, T., Umeda, T., Morimoto, Y., Naguro, I., Tobiume, K., Saitoh, M., Matsuzawa, A., and Ichijo, H. (2007) Apoptosis signal-regulating kinase 2 (ASK2) functions as a mitogen-activated protein kinase kinase kinase in a heteromeric complex with ASK1. J. Biol. Chem. 282, 7522-7531 (Pubitemid 47093697)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.10
, pp. 7522-7531
-
-
Takeda, K.1
Shimozono, R.2
Noguchi, T.3
Umeda, T.4
Morimoto, Y.5
Naguro, I.6
Tobiume, K.7
Saitoh, M.8
Matsuzawa, A.9
Ichijo, H.10
-
25
-
-
0030918591
-
MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase
-
DOI 10.1074/jbc.272.24.15167
-
Hirai, S., Katoh, M., Terada, M., Kyriakis, J. M., Zon, L. I., Rana, A., Avruch, J., and Ohno, S. (1997) MST/MLK2, a member of the mixed lineage kinase family, directly phosphorylates and activates SEK1, an activator of c-Jun N-terminal kinase/stress-activated protein kinase. J. Biol. Chem. 272, 15167-15173 (Pubitemid 27255532)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.24
, pp. 15167-15173
-
-
Hirai, S.-I.1
Katoh, M.2
Terada, M.3
Kyriakis, J.M.4
Zon, L.I.5
Rana, A.6
Avruch, J.7
Ohno, S.8
-
26
-
-
0034061264
-
Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation
-
DOI 10.1128/MCB.20.7.2334-2342.2000
-
Cheng, J., Yang, J., Xia, Y., Karin, M., and Su, B. (2000) Synergistic interaction of MEK kinase 2, c-Jun N-terminal kinase (JNK) kinase 2, and JNK1 results in efficient and specific JNK1 activation. Mol. Cell. Biol. 20, 2334-2342 (Pubitemid 30152041)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.7
, pp. 2334-2342
-
-
Cheng, J.1
Yang, J.2
Xia, X.3
Karin, M.4
Su, S.5
-
27
-
-
33845992547
-
E2F1 modulates p38 MAPK phosphorylation via transcriptional regulation of ASK1 and Wip1
-
DOI 10.1074/jbc.M601758200
-
Hershko, T., Korotayev, K., Polager, S., and Ginsberg, D. (2006) E2F1 modulates p38 MAPK phosphorylation via transcriptional regulation of ASK1 and Wip1. J. Biol. Chem. 281, 31309-31316 (Pubitemid 46041395)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.42
, pp. 31309-31316
-
-
Hershko, T.1
Korotayev, K.2
Polager, S.3
Ginsberg, D.4
-
28
-
-
70450235184
-
Regulation of p53. Insights into a complex process
-
Boehme, K. A., and Blattner, C. (2009) Regulation of p53. Insights into a complex process. Crit. Rev. Biochem. Mol. Biol. 44, 367-392
-
(2009)
Crit. Rev. Biochem. Mol. Biol.
, vol.44
, pp. 367-392
-
-
Boehme, K.A.1
Blattner, C.2
-
29
-
-
0028943245
-
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2
-
Lin, A., Minden, A., Martinetto, H., Claret, F. X., Lange-Carter, C., Mercurio, F., Johnson, G. L., and Karin, M. (1995) Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science 268, 286-290
-
(1995)
Science
, vol.268
, pp. 286-290
-
-
Lin, A.1
Minden, A.2
Martinetto, H.3
Claret, F.X.4
Lange-Carter, C.5
Mercurio, F.6
Johnson, G.L.7
Karin, M.8
-
30
-
-
0034757779
-
Cell cycle regulation by p38 MAP kinases
-
DOI 10.1016/S0248-4900(01)01124-8
-
Ambrosino, C., and Nebreda, A. R. (2001) Cell cycle regulation by p38 MAP kinases. Biol. Cell 93, 47-51 (Pubitemid 33040859)
-
(2001)
Biology of the Cell
, vol.93
, Issue.1-2
, pp. 47-51
-
-
Ambrosino, C.1
Nebreda, A.R.2
-
31
-
-
0031009434
-
Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK
-
Molnár, A., Theodoras, A. M., Zon, L. I., and Kyriakis, J. M. (1997) Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK. J. Biol. Chem. 272, 13229-13235
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13229-13235
-
-
Molnár, A.1
Theodoras, A.M.2
Zon, L.I.3
Kyriakis, J.M.4
-
32
-
-
77951911205
-
Inhibition of centriole duplication by centrobin depletion leads to p38-p53-mediated cell cycle arrest
-
Song, L., Dai, T., Xiong, H., Lin, C., Lin, H., Shi, T., and Li, J. (2010) Inhibition of centriole duplication by centrobin depletion leads to p38-p53-mediated cell cycle arrest. Cell. Signal. 22, 857-864
-
(2010)
Cell. Signal.
, vol.22
, pp. 857-864
-
-
Song, L.1
Dai, T.2
Xiong, H.3
Lin, C.4
Lin, H.5
Shi, T.6
Li, J.7
-
33
-
-
33947270830
-
Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest
-
DOI 10.1038/ncb1529, PII NCB1529
-
Mikule, K., Delaval, B., Kaldis, P., Jurcyzk, A., Hergert, P., and Doxsey, S. (2007) Loss of centrosome integrity induces p38-p53-p21-dependent G1-S arrest. Nat. Cell Biol. 9, 160-170 (Pubitemid 46420858)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.2
, pp. 160-170
-
-
Mikule, K.1
Delaval, B.2
Kaldis, P.3
Jurcyzk, A.4
Hergert, P.5
Doxsey, S.6
-
34
-
-
2442675270
-
1 cell cycle arrest
-
DOI 10.1038/sj.onc.1207467
-
Todd, D. E., Densham, R. M., Molton, S. A., Balmanno, K., Newson, C., Weston, C. R., Garner, A. P., Scott, L., and Cook, S. J. (2004) ERK1/2 and p38 cooperate to induce a p21CIP1-dependent G1 cell cycle arrest. Oncogene 23, 3284-3295 (Pubitemid 38669818)
-
(2004)
Oncogene
, vol.23
, Issue.19
, pp. 3284-3295
-
-
Todd, D.E.1
Densham, R.M.2
Molton, S.A.3
Balmanno, K.4
Newson, C.5
Weston, C.R.6
Garner, A.P.7
Scott, L.8
Cook, S.J.9
-
35
-
-
68949161769
-
P38 mitogen-activated protein kinase- And HuR-dependent stabilization of p21(Cip1) mRNA mediates the G1/S checkpoint
-
Lafarga, V., Cuadrado, A., Lopez de Silanes, I., Bengoechea, R., Fernandez-Capetillo, O., and Nebreda, A. R. (2009) p38 mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G1/S checkpoint. Mol. Cell. Biol. 29, 4341-4351
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4341-4351
-
-
Lafarga, V.1
Cuadrado, A.2
Lopez De Silanes, I.3
Bengoechea, R.4
Fernandez-Capetillo, O.5
Nebreda, A.R.6
-
36
-
-
4944255743
-
Post-translational modification of p53 in tumorigenesis
-
DOI 10.1038/nrc1455
-
Bode, A. M., and Dong, Z. (2004) Post-translational modification of p53 in tumorigenesis. Nat. Rev. Cancer 4, 793-805 (Pubitemid 39331151)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.10
, pp. 793-805
-
-
Bode, A.M.1
Dong, Z.2
-
37
-
-
0037186149
-
Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20
-
She, Q. B., Ma, W. Y., and Dong, Z. (2002) Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20. Oncogene 21, 1580-1589
-
(2002)
Oncogene
, vol.21
, pp. 1580-1589
-
-
She, Q.B.1
Ma, W.Y.2
Dong, Z.3
-
38
-
-
0032169459
-
JNK targets p53 ubiquitination and degradation in nonstressed cells
-
Fuchs, S. Y., Adler, V., Buschmann, T., Yin, Z., Wu, X., Jones, S. N., and Ronai, Z. (1998) JNK targets p53 ubiquitination and degradation in non-stressed cells. Genes Dev. 12, 2658-2663 (Pubitemid 28420646)
-
(1998)
Genes and Development
, vol.12
, Issue.17
, pp. 2658-2663
-
-
Fuchs, S.Y.1
Adler, V.2
Buschmann, T.3
Yin, Z.4
Wu, X.5
Jones, S.N.6
Ronai, Z.7
-
39
-
-
69149097080
-
Control of p53 multimerization by Ubc13 is JNK-regulated
-
Topisirovic, I., Gutierrez, G. J., Chen, M., Appella, E., Borden, K. L., and Ronai, Z. A. (2009) Control of p53 multimerization by Ubc13 is JNK-regulated. Proc. Natl. Acad. Sci. U.S.A. 106, 12676-12681
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 12676-12681
-
-
Topisirovic, I.1
Gutierrez, G.J.2
Chen, M.3
Appella, E.4
Borden, K.L.5
Ronai, Z.A.6
-
40
-
-
54249119561
-
JNK signaling in apoptosis
-
Dhanasekaran, D. N., and Reddy, E. P. (2008) JNK signaling in apoptosis. Oncogene 27, 6245-6251
-
(2008)
Oncogene
, vol.27
, pp. 6245-6251
-
-
Dhanasekaran, D.N.1
Reddy, E.P.2
-
41
-
-
69949084408
-
Gene expression profiling of bone marrow endothelial cells in patients with multiple myeloma
-
Ria, R., Todoerti, K., Berardi, S., Coluccia, A. M., De Luisi, A., Mattioli, M., Ronchetti, D., Morabito, F., Guarini, A., Petrucci, M. T., Dammacco, F., Ribatti, D., Neri, A., and Vacca, A. (2009) Gene expression profiling of bone marrow endothelial cells in patients with multiple myeloma. Clin. Cancer Res. 15, 5369-5378
-
(2009)
Clin. Cancer Res.
, vol.15
, pp. 5369-5378
-
-
Ria, R.1
Todoerti, K.2
Berardi, S.3
Coluccia, A.M.4
De Luisi, A.5
Mattioli, M.6
Ronchetti, D.7
Morabito, F.8
Guarini, A.9
Petrucci, M.T.10
Dammacco, F.11
Ribatti, D.12
Neri, A.13
Vacca, A.14
-
42
-
-
67650227500
-
Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity
-
Blüher, M., Bashan, N., Shai, I., Harman-Boehm, I., Tarnovscki, T., Avinaoch, E., Stumvoll, M., Dietrich, A., Klöting, N., and Rudich, A. (2009) Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity. J. Clin. Endocrinol. Metab. 94, 2507-2515
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 2507-2515
-
-
Blüher, M.1
Bashan, N.2
Shai, I.3
Harman-Boehm, I.4
Tarnovscki, T.5
Avinaoch, E.6
Stumvoll, M.7
Dietrich, A.8
Klöting, N.9
Rudich, A.10
-
43
-
-
67749117934
-
Signal integration by JNK and p38 MAPK pathways in cancer development
-
Wagner, E. F., and Nebreda, A. R. (2009) Signal integration by JNK and p38 MAPK pathways in cancer development. Nat. Rev. Cancer 9, 537-549
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 537-549
-
-
Wagner, E.F.1
Nebreda, A.R.2
-
44
-
-
34248179139
-
The potential for signal integration and processing in interacting MAP kinase cascades
-
DOI 10.1016/j.jtbi.2006.12.035, PII S0022519306006035
-
Schwacke, J. H., and Voit, E. O. (2007) The potential for signal integration and processing in interacting MAP kinase cascades. J. Theor. Biol. 246, 604-620 (Pubitemid 46719256)
-
(2007)
Journal of Theoretical Biology
, vol.246
, Issue.4
, pp. 604-620
-
-
Schwacke, J.H.1
Voit, E.O.2
-
45
-
-
79955462543
-
Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1
-
Yu, Y., and Richardson, D. R. (2011) Cellular iron depletion stimulates the JNK and p38 MAPK signaling transduction pathways, dissociation of ASK1-thioredoxin, and activation of ASK1. J. Biol. Chem. 286, 15413-15427
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 15413-15427
-
-
Yu, Y.1
Richardson, D.R.2
-
46
-
-
30644468596
-
JNK/SAPK and p38 SAPK-2 mediate mechanical stretch-induced apoptosis via caspase-3 and -9 in NRK-52E renal epithelial cells
-
DOI 10.1159/000088401
-
Nguyen, H. T., Hsieh, M. H., Gaborro, A., Tinloy, B., Phillips, C., and Adam, R. M. (2006) JNK/SAPK and p38 SAPK-2 mediate mechanical stretch-induced apoptosis via caspase-3 and -9 in NRK-52E renal epithelial cells. Nephron. Exp. Nephrol. 102, e49-61 (Pubitemid 43087566)
-
(2006)
Nephron - Experimental Nephrology
, vol.102
, Issue.2
-
-
Nguyen, H.T.1
Hsieh, M.H.2
Gaborro, A.3
Tinloy, B.4
Phillips, C.5
Adam, R.M.6
-
47
-
-
0034806972
-
Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress
-
DOI 10.1128/MCB.21.20.6913-6926.2001
-
Benhar, M., Dalyot, I., Engelberg, D., and Levitzki, A. (2001) Enhanced ROS production in oncogenically transformed cells potentiates c-Jun Nterminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress. Mol. Cell. Biol. 21, 6913-6926 (Pubitemid 32911252)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.20
, pp. 6913-6926
-
-
Benhar, M.1
Dalyot, I.2
Engelberg, D.3
Levitzki, A.4
-
48
-
-
0141733164
-
Phosphorylation site interdependence of human p53 post-translational modifications in response to stress
-
DOI 10.1074/jbc.M305135200
-
Saito, S., Yamaguchi, H., Higashimoto, Y., Chao, C., Xu, Y., Fornace, A. J., Jr., Appella, E., and Anderson, C. W. (2003) Phosphorylation site interdependence of human p53 post-translational modifications in response to stress. J. Biol. Chem. 278, 37536-37544 (Pubitemid 37175275)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 37536-37544
-
-
Saito, S.1
Yamaguchi, H.2
Higashimoto, Y.3
Chao, C.4
Xu, Y.5
Fornace Jr., A.J.6
Appella, E.7
Anderson, C.W.8
-
49
-
-
37549071097
-
Solution structure of selenoprotein W and NMR analysis of its interaction with 14-3-3 proteins
-
Aachmann, F. L., Fomenko, D. E., Soragni, A., Gladyshev, V. N., and Dikiy, A. (2007) Solution structure of selenoprotein W and NMR analysis of its interaction with 14-3-3 proteins. J. Biol. Chem. 282, 37036-37044
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 37036-37044
-
-
Aachmann, F.L.1
Fomenko, D.E.2
Soragni, A.3
Gladyshev, V.N.4
Dikiy, A.5
-
50
-
-
34250175829
-
SelT, SelW, SelH, and Rdx 12: Genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family
-
DOI 10.1021/bi602462q
-
Dikiy, A., Novoselov, S. V., Fomenko, D. E., Sengupta, A., Carlson, B. A., Cerny, R. L., Ginalski, K., Grishin, N. V., Hatfield, D. L., and Gladyshev, V. N. (2007) SelT, SelW, SelH, and Rdx12. Genomics and molecular insights into the functions of selenoproteins of a novel thioredoxin-like family. Biochemistry 46, 6871-6882 (Pubitemid 46906416)
-
(2007)
Biochemistry
, vol.46
, Issue.23
, pp. 6871-6882
-
-
Dikiy, A.1
Novoselov, S.V.2
Fomenko, D.E.3
Sengupta, A.4
Carlson, B.A.5
Cerny, R.L.6
Ginalski, K.7
Grishin, N.V.8
Hatfield, D.L.9
Gladyshev, V.N.10
-
51
-
-
79953142901
-
14-3-3γ inhibition of MDMX-mediated p21 turnover independent of p53
-
Lee, J. H., and Lu, H. (2011) 14-3-3γ inhibition of MDMX-mediated p21 turnover independent of p53. J. Biol. Chem. 286, 5136-5142
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 5136-5142
-
-
Lee, J.H.1
Lu, H.2
-
52
-
-
11144241301
-
A role for 14-3-3τ in E2F1 stabilization and DNA damage-induced apoptosis
-
DOI 10.1074/jbc.M410493200
-
Wang, B., Liu, K., Lin, F. T., and Lin, W. C. (2004) A role for 14-3-3 tau in E2F1 stabilization and DNA damage-induced apoptosis. J. Biol. Chem. 279, 54140-54152 (Pubitemid 40053150)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.52
, pp. 54140-54152
-
-
Wang, B.1
Liu, K.2
Lin, F.-T.3
Lin, W.-C.4
-
53
-
-
0141529779
-
14-3-3σ positively regulates p53 and suppresses tumor growth
-
DOI 10.1128/MCB.23.20.7096-7107.2003
-
Yang, H. Y., Wen, Y. Y., Chen, C. H., Lozano, G., and Lee, M. H. (2003) 14-3-3δ positively regulates p53 and suppresses tumor growth. Mol. Cell. Biol. 23, 7096-7107 (Pubitemid 37210993)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.20
, pp. 7096-7107
-
-
Yang, H.-Y.1
Wen, Y.-Y.2
Chen, C.-H.3
Lozano, G.4
Lee, M.-H.5
-
54
-
-
77954374360
-
14-3-3ε dynamically interacts with key components of mitogen-activated protein kinase signal module for selective modulation of the TNF-α-induced time course-dependent NF-κB activity
-
Zuo, S., Xue, Y., Tang, S., Yao, J., Du, R., Yang, P., and Chen, X. (2010) 14-3-3ε dynamically interacts with key components of mitogen-activated protein kinase signal module for selective modulation of the TNF-α-induced time course-dependent NF-κB activity. J. Proteome Res. 9, 3465-3478
-
(2010)
J. Proteome Res.
, vol.9
, pp. 3465-3478
-
-
Zuo, S.1
Xue, Y.2
Tang, S.3
Yao, J.4
Du, R.5
Yang, P.6
Chen, X.7
-
55
-
-
0032488910
-
14-3-3 proteins interact with specific MEK kinases
-
DOI 10.1074/jbc.273.6.3476
-
Fanger, G. R., Widmann, C., Porter, A. C., Sather, S., Johnson, G. L., and Vaillancourt, R. R. (1998) 14-3-3 proteins interact with specific MEK kinases. J. Biol. Chem. 273, 3476-3483 (Pubitemid 28109768)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.6
, pp. 3476-3483
-
-
Fanger, G.R.1
Widmann, C.2
Porter, A.C.3
Sather, S.4
Johnson, G.L.5
Vaillancourt, R.R.6
-
56
-
-
1542365347
-
14-3-3β Binds to Big Mitogen-activated Protein Kinase 1 (BMK1/ERK5) and Regulates BMK1 Function
-
DOI 10.1074/jbc.M310212200
-
Zheng, Q., Yin, G., Yan, C., Cavet, M., and Berk, B. C. (2004) 14-3-3β binds to big mitogen-activated protein kinase 1 (BMK1/ERK5) and regulates BMK1 function. J. Biol. Chem. 279, 8787-8791 (Pubitemid 38295936)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.10
, pp. 8787-8791
-
-
Zheng, Q.1
Yin, G.2
Yan, C.3
Cavet, M.4
Berk, B.C.5
-
57
-
-
77950872530
-
Bioinformatic and experimental survey of 14-3-3-binding sites
-
Johnson, C., Crowther, S., Stafford, M. J., Campbell, D. G., Toth, R., and MacKintosh, C. (2010) Bioinformatic and experimental survey of 14-3-3-binding sites. Biochem. J. 427, 69-78
-
(2010)
Biochem. J.
, vol.427
, pp. 69-78
-
-
Johnson, C.1
Crowther, S.2
Stafford, M.J.3
Campbell, D.G.4
Toth, R.5
MacKintosh, C.6
-
58
-
-
34447531013
-
RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation
-
DOI 10.1074/jbc.M701148200
-
Zhang, H., Zhang, R., Zhang, H., Lin, Y., Li, J., Pober, J. S., and Min, W. (2007) RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation. J. Biol. Chem. 282, 14788-14796 (Pubitemid 47093366)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.20
, pp. 14788-14796
-
-
Zhang, R.1
Zhang, H.2
Lin, Y.3
Li, J.4
Pober, J.S.5
Min, W.6
-
59
-
-
0344011971
-
Role of 14-3-3-Mediated p38 Mitogen-Activated Protein Kinase Inhibition in Cardiac Myocyte Survival
-
DOI 10.1161/01.RES.0000104084.88317.91
-
Zhang, S., Ren, J., Zhang, C. E., Treskov, I., Wang, Y., and Muslin, A. J. (2003) Role of 14-3-3-mediated p38 mitogen-activated protein kinase inhibition in cardiac myocyte survival. Circ. Res. 93, 1026-1028 (Pubitemid 37485032)
-
(2003)
Circulation Research
, vol.93
, Issue.11
, pp. 1026-1028
-
-
Zhang, S.1
Ren, J.2
Zhang, C.E.3
Treskov, I.4
Wang, Y.5
Muslin, A.J.6
-
60
-
-
0034141550
-
14-3-3 Proteins block apoptosis and differentially regulate MAPK cascades
-
Xing, H., Zhang, S., Weinheimer, C., Kovacs, A., and Muslin, A. J. (2000) 14-3-3 proteins block apoptosis and differentially regulate MAPK cascades. EMBO J. 19, 349-358 (Pubitemid 30072605)
-
(2000)
EMBO Journal
, vol.19
, Issue.3
, pp. 349-358
-
-
Xing, H.1
Zhang, S.2
Weinheimer, C.3
Kovacs, A.4
Muslin, A.J.5
-
61
-
-
80054041183
-
Visualization and biochemical analyses of the emerging mammalian 14-3-3-phosphoproteome
-
Johnson, C., Tinti, M., Wood, N. T., Campbell, D. G., Toth, R., Dubois, F., Geraghty, K. M., Wong, B. H., Brown, L. J., Tyler, J., Gernez, A., Chen, S., Synowsky, S., and MacKintosh, C. (2011) Visualization and biochemical analyses of the emerging mammalian 14-3-3-phosphoproteome. Mol. Cell. Proteomics 10, 1-15
-
(2011)
Mol. Cell. Proteomics
, vol.10
, pp. 1-15
-
-
Johnson, C.1
Tinti, M.2
Wood, N.T.3
Campbell, D.G.4
Toth, R.5
Dubois, F.6
Geraghty, K.M.7
Wong, B.H.8
Brown, L.J.9
Tyler, J.10
Gernez, A.11
Chen, S.12
Synowsky, S.13
MacKintosh, C.14
-
62
-
-
34249296250
-
Post-transcriptional control of the Saccharomyces cerevisiae proteome by 14-3-3 proteins
-
DOI 10.1021/pr0605522
-
Bruckmann, A., Hensbergen, P. J., Balog, C. I., Deelder, A. M., de Steensma, H. Y., and van Heusden, G. P. (2007) Post-transcriptional control of the Saccharomyces cerevisiae proteome by 14-3-3 proteins. J. Proteome Res. 6, 1689-1699 (Pubitemid 46814493)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.5
, pp. 1689-1699
-
-
Bruckmann, A.1
Hensbergen, P.J.2
Balog, C.I.A.3
Deelder, A.M.4
Steensma, H.Y.5
Van Heusden, G.P.H.6
-
63
-
-
33947236863
-
14-3-3σ controls mitotic translation to facilitate cytokinesis
-
DOI 10.1038/nature05584, PII NATURE05584
-
Wilker, E. W., van Vugt, M. A., Artim, S. A., Huang, P. H., Petersen, C. P., Reinhardt, H. C., Feng, Y., Sharp, P. A., Sonenberg, N., White, F. M., and Yaffe, M. B. (2007) 14-3-3δ controls mitotic translation to facilitate cytokinesis. Nature 446, 329-332 (Pubitemid 46426148)
-
(2007)
Nature
, vol.446
, Issue.7133
, pp. 329-332
-
-
Wilker, E.W.1
Van Vugt, M.A.T.M.2
Artim, S.A.3
Huang, P.H.4
Petersen, C.P.5
Reinhardt, H.C.6
Feng, Y.7
Sharp, P.A.8
Sonenberg, N.9
White, F.M.10
Yaffe, M.B.11
-
64
-
-
0037080168
-
Eukaryotic initiation factor 2α subunit associates with TGFβ receptors and 14-3-3ε and acts as a modulator of the TGFβ response
-
DOI 10.1021/bi011407z
-
McGonigle, S., Beall, M. J., and Pearce, E. J. (2002) Eukaryotic initiation factor 2 α-subunit associates with TGFβ receptors and 14-3-3ε and acts as a modulator of the TGFβ response. Biochemistry 41, 579-587 (Pubitemid 34062028)
-
(2002)
Biochemistry
, vol.41
, Issue.2
, pp. 579-587
-
-
McGonigle, S.1
Beall, M.J.2
Pearce, E.J.3
-
65
-
-
77950664407
-
Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3
-
Larance, M., Rowland, A. F., Hoehn, K. L., Humphreys, D. T., Preiss, T., Guilhaus, M., and James, D. E. (2010) Global phosphoproteomics identifies a major role for AKT and 14-3-3 in regulating EDC3. Mol. Cell. Proteomics 9, 682-694
-
(2010)
Mol. Cell. Proteomics
, vol.9
, pp. 682-694
-
-
Larance, M.1
Rowland, A.F.2
Hoehn, K.L.3
Humphreys, D.T.4
Preiss, T.5
Guilhaus, M.6
James, D.E.7
-
66
-
-
33845900214
-
14-3-3 protein binds to the low molecular weight neurofilament (NFL) mRNA 3′ UTR
-
DOI 10.1016/j.mcn.2006.10.001, PII S1044743106002132
-
Ge, W. W., Volkening, K., Leystra-Lantz, C., Jaffe, H., and Strong, M. J. (2007) 14-3-3 protein binds to the low molecular weight neurofilament (NFL) mRNA 3′-UTR. Mol. Cell. Neurosci. 34, 80-87 (Pubitemid 46026930)
-
(2007)
Molecular and Cellular Neuroscience
, vol.34
, Issue.1
, pp. 80-87
-
-
Ge, W.-w.1
Volkening, K.2
Leystra-Lantz, C.3
Jaffe, H.4
Strong, M.J.5
-
67
-
-
0034674566
-
Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations
-
DOI 10.1074/jbc.M000690200
-
Zhong, L., and Holmgren, A. (2000) Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations. J. Biol. Chem. 275, 18121-18128 (Pubitemid 30414762)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.24
, pp. 18121-18128
-
-
Zhong, L.1
Holmgren, A.2
|