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Volumn 20, Issue 2, 2015, Pages 131-143

Harnessing the therapeutic potential of micrornas for cardiovascular disease

Author keywords

cardiovascular disease; microRNA; therapeutics

Indexed keywords

ANTAGOMIR; MICRORNA; VIRUS VECTOR;

EID: 84922608916     PISSN: 10742484     EISSN: 19404034     Source Type: Journal    
DOI: 10.1177/1074248414552902     Document Type: Review
Times cited : (16)

References (124)
  • 1
    • 84893651437 scopus 로고    scopus 로고
    • Heart disease and stroke statistics - 2014 update: A report from the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics - 2014 update: a report from the American Heart Association. Circulation. 2014 ; 129 (3). e28 - e292
    • (2014) Circulation , vol.129 , Issue.3 , pp. 28-e292
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 2
    • 84856751210 scopus 로고    scopus 로고
    • Developing microRNA therapeutics
    • van Rooij E, Purcell AL, Levin AA. Developing microRNA therapeutics. Circ Res. 2012 ; 110 (3). 496-507
    • (2012) Circ Res , vol.110 , Issue.3 , pp. 496-507
    • Van Rooij, E.1    Purcell, A.L.2    Levin, A.A.3
  • 3
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004 ; 116 (2). 281-297
    • (2004) Cell , vol.116 , Issue.2 , pp. 281-297
    • Bartel, D.P.1
  • 4
    • 84858379476 scopus 로고    scopus 로고
    • MicroRNAs in stress signaling and human disease
    • Mendell JT, Olson EN. MicroRNAs in stress signaling and human disease. Cell. 2012 ; 148 (6). 1172-1187
    • (2012) Cell , vol.148 , Issue.6 , pp. 1172-1187
    • Mendell, J.T.1    Olson, E.N.2
  • 5
    • 79959463758 scopus 로고    scopus 로고
    • MicroRNA expression profiling reveals miRNA families regulating specific biological pathways in mouse frontal cortex and hippocampus
    • Juhila J, Sipila T, Icay K, et al. MicroRNA expression profiling reveals miRNA families regulating specific biological pathways in mouse frontal cortex and hippocampus. PLoS One. 2011 ; 6 (6). e21495
    • (2011) PLoS One , vol.6 , Issue.6 , pp. 21495
    • Juhila, J.1    Sipila, T.2    Icay, K.3
  • 6
    • 84878403310 scopus 로고    scopus 로고
    • MicroRNA-99 family targets AKT/mTOR signaling pathway in dermal wound healing
    • Jin Y, Tymen SD, Chen D, et al. MicroRNA-99 family targets AKT/mTOR signaling pathway in dermal wound healing. PLoS One. 2013 ; 8 (5). e64434
    • (2013) PLoS One , vol.8 , Issue.5 , pp. 64434
    • Jin, Y.1    Tymen, S.D.2    Chen, D.3
  • 7
    • 51349141401 scopus 로고    scopus 로고
    • Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
    • van Rooij E, Sutherland LB, Thatcher JE, et al. Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci USA. 2008 ; 105 (35). 13027-13032
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.35 , pp. 13027-13032
    • Van Rooij, E.1    Sutherland, L.B.2    Thatcher, J.E.3
  • 8
    • 84870915144 scopus 로고    scopus 로고
    • MicroRNAs in chronic lymphocytic leukemia: From causality to associations and back
    • Mraz M, Pospisilova S. MicroRNAs in chronic lymphocytic leukemia: from causality to associations and back. Expert Rev Hematol. 2012 ; 5 (6). 579-581
    • (2012) Expert Rev Hematol , vol.5 , Issue.6 , pp. 579-581
    • Mraz, M.1    Pospisilova, S.2
  • 9
    • 84857400300 scopus 로고    scopus 로고
    • Biological robustness and the role of microRNAs: A network perspective
    • Pelaez N, Carthew RW. Biological robustness and the role of microRNAs: a network perspective. Curr Top Dev Biol. 2012 ; 99: 237-255
    • (2012) Curr Top Dev Biol , vol.99 , pp. 237-255
    • Pelaez, N.1    Carthew, R.W.2
  • 10
    • 84862793489 scopus 로고    scopus 로고
    • Wang DZ. MicroRNAs in cardiovascular development
    • Chen J. Wang DZ. microRNAs in cardiovascular development. J Mol Cell Cardiol. 2012 ; 52 (5). 949-957
    • (2012) J Mol Cell Cardiol , vol.52 , Issue.5 , pp. 949-957
    • Chen, J.1
  • 11
    • 41149147013 scopus 로고    scopus 로고
    • Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
    • Chen JF, Murchison EP, Tang R, et al. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci USA. 2008 ; 105 (6). 2111-2116
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.6 , pp. 2111-2116
    • Chen, J.F.1    Murchison, E.P.2    Tang, R.3
  • 12
    • 84877251524 scopus 로고    scopus 로고
    • Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer
    • Hashimoto Y, Akiyama Y, Yuasa Y. Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer. PLoS One. 2013 ; 8 (5). e62589
    • (2013) PLoS One , vol.8 , Issue.5 , pp. 62589
    • Hashimoto, Y.1    Akiyama, Y.2    Yuasa, Y.3
  • 13
    • 84857636799 scopus 로고    scopus 로고
    • MicroRNAs in hypertension: Mechanisms and therapeutic targets
    • Batkai S, Thum T. MicroRNAs in hypertension: mechanisms and therapeutic targets. Curr Hypertens Rep. 2012 ; 14 (1). 79-87
    • (2012) Curr Hypertens Rep , vol.14 , Issue.1 , pp. 79-87
    • Batkai, S.1    Thum, T.2
  • 15
    • 84891848945 scopus 로고    scopus 로고
    • MicroRNA therapeutics in cardiovascular disease models
    • Dangwal S. Thum T. microRNA therapeutics in cardiovascular disease models. Annu Rev Pharmacol Toxicol. 2014 ; 54: 185-203
    • (2014) Annu Rev Pharmacol Toxicol , vol.54 , pp. 185-203
    • Dangwal, S.1    Thum, T.2
  • 16
    • 84896727760 scopus 로고    scopus 로고
    • FibromiRs: Translating molecular discoveries into new anti-fibrotic drugs
    • Pottier N, Cauffiez C, Perrais M, Barbry P, Mari B. FibromiRs: translating molecular discoveries into new anti-fibrotic drugs. Trends Pharmacol Sci. 2014 ; 35 (3). 119-126
    • (2014) Trends Pharmacol Sci , vol.35 , Issue.3 , pp. 119-126
    • Pottier, N.1    Cauffiez, C.2    Perrais, M.3    Barbry, P.4    Mari, B.5
  • 18
    • 84855244103 scopus 로고    scopus 로고
    • MicroRNA therapeutics in cardiovascular medicine
    • Thum T. MicroRNA therapeutics in cardiovascular medicine. EMBO Mol Med. 2012 ; 4 (1). 3-14
    • (2012) EMBO Mol Med , vol.4 , Issue.1 , pp. 3-14
    • Thum, T.1
  • 20
    • 57749169283 scopus 로고    scopus 로고
    • Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat
    • Bish LT, Morine K, Sleeper MM, et al. Adeno-associated virus (AAV) serotype 9 provides global cardiac gene transfer superior to AAV1, AAV6, AAV7, and AAV8 in the mouse and rat. Hum Gene Ther. 2008 ; 19 (12). 1359-1368
    • (2008) Hum Gene Ther , vol.19 , Issue.12 , pp. 1359-1368
    • Bish, L.T.1    Morine, K.2    Sleeper, M.M.3
  • 21
    • 0023651145 scopus 로고
    • Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides
    • Inoue H, Hayase Y, Imura A, Iwai S, Miura K, Ohtsuka E. Synthesis and hybridization studies on two complementary nona(2′-O-methyl)ribonucleotides. Nucleic Acids Res. 1987 ; 15 (15). 6131-6148
    • (1987) Nucleic Acids Res , vol.15 , Issue.15 , pp. 6131-6148
    • Inoue, H.1    Hayase, Y.2    Imura, A.3    Iwai, S.4    Miura, K.5    Ohtsuka, E.6
  • 22
    • 0035119936 scopus 로고    scopus 로고
    • Pharmacokinetic properties of 2′-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats
    • Geary RS, Watanabe TA, Truong L, et al. Pharmacokinetic properties of 2′-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats. J Pharmacol Exp Ther. 2001 ; 296 (3). 890-897
    • (2001) J Pharmacol Exp Ther , vol.296 , Issue.3 , pp. 890-897
    • Geary, R.S.1    Watanabe, T.A.2    Truong, L.3
  • 23
    • 84855350458 scopus 로고    scopus 로고
    • Inhibition of miR-15 protects against cardiac ischemic injury
    • Hullinger TG, Montgomery RL, Seto AG, et al. Inhibition of miR-15 protects against cardiac ischemic injury. Circ Res. 2012 ; 110 (1). 71-81
    • (2012) Circ Res , vol.110 , Issue.1 , pp. 71-81
    • Hullinger, T.G.1    Montgomery, R.L.2    Seto, A.G.3
  • 24
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • Krutzfeldt J, Rajewsky N, Braich R, et al. Silencing of microRNAs in vivo with 'antagomirs'. Nature. 2005 ; 438 (7068). 685-689
    • (2005) Nature , vol.438 , Issue.7068 , pp. 685-689
    • Krutzfeldt, J.1    Rajewsky, N.2    Braich, R.3
  • 25
    • 34547381047 scopus 로고    scopus 로고
    • LNA (locked nucleic acid) and analogs as triplex-forming oligonucleotides
    • Hojland T, Kumar S, Babu BR, et al. LNA (locked nucleic acid) and analogs as triplex-forming oligonucleotides. Org Biomol Chem. 2007 ; 5 (15). 2375-2379
    • (2007) Org Biomol Chem , vol.5 , Issue.15 , pp. 2375-2379
    • Hojland, T.1    Kumar, S.2    Babu, B.R.3
  • 26
    • 84877132387 scopus 로고    scopus 로고
    • MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation
    • Luo X, Pan Z, Shan H, et al. MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation. J Clin Invest. 2013 ; 123 (5). 1939-1951
    • (2013) J Clin Invest , vol.123 , Issue.5 , pp. 1939-1951
    • Luo, X.1    Pan, Z.2    Shan, H.3
  • 27
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • Ebert MS, Neilson JR, Sharp PA. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods. 2007 ; 4 (9). 721-726
    • (2007) Nat Methods , vol.4 , Issue.9 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 28
    • 84899482237 scopus 로고    scopus 로고
    • Inhibition of miR-25 improves cardiac contractility in the failing heart
    • Wahlquist C, Jeong D, Rojas-Munoz A, et al. Inhibition of miR-25 improves cardiac contractility in the failing heart. Nature. 2014 ; 508 (7497). 531-535
    • (2014) Nature , vol.508 , Issue.7497 , pp. 531-535
    • Wahlquist, C.1    Jeong, D.2    Rojas-Munoz, A.3
  • 29
    • 84880816481 scopus 로고    scopus 로고
    • Therapeutic cardiac-targeted delivery of miR-1 reverses pressure overload-induced cardiac hypertrophy and attenuates pathological remodeling
    • Karakikes I, Chaanine AH, Kang S, et al. Therapeutic cardiac-targeted delivery of miR-1 reverses pressure overload-induced cardiac hypertrophy and attenuates pathological remodeling. J Am Heart Assoc. 2013 ; 2 (2). e000078
    • (2013) J Am Heart Assoc , vol.2 , Issue.2 , pp. 000078
    • Karakikes, I.1    Chaanine, A.H.2    Kang, S.3
  • 30
    • 84862025459 scopus 로고    scopus 로고
    • Directed evolution of novel adeno-associated viruses for therapeutic gene delivery
    • Bartel MA, Weinstein JR, Schaffer DV. Directed evolution of novel adeno-associated viruses for therapeutic gene delivery. Gene Ther. 2012 ; 19 (6). 694-700
    • (2012) Gene Ther , vol.19 , Issue.6 , pp. 694-700
    • Ma, B.1    Weinstein, J.R.2    Schaffer, D.V.3
  • 31
    • 84893745114 scopus 로고    scopus 로고
    • Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer
    • Kong W, He L, Richards EJ, et al. Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer. Oncogene. 2014 ; 33 (6). 679-689
    • (2014) Oncogene , vol.33 , Issue.6 , pp. 679-689
    • Kong, W.1    He, L.2    Richards, E.J.3
  • 32
    • 58149252151 scopus 로고    scopus 로고
    • Stable knockdown of microRNA in vivo by lentiviral vectors
    • Gentner B, Schira G, Giustacchini A, et al. Stable knockdown of microRNA in vivo by lentiviral vectors. Nat Methods. 2009 ; 6 (1). 63-66
    • (2009) Nat Methods , vol.6 , Issue.1 , pp. 63-66
    • Gentner, B.1    Schira, G.2    Giustacchini, A.3
  • 34
    • 84859440283 scopus 로고    scopus 로고
    • The AAV vector toolkit: Poised at the clinical crossroads
    • Asokan A, Schaffer DV, Samulski RJ. The AAV vector toolkit: poised at the clinical crossroads. Mol Ther. 2012 ; 20 (4). 699-708
    • (2012) Mol Ther , vol.20 , Issue.4 , pp. 699-708
    • Asokan, A.1    Schaffer, D.V.2    Samulski, R.J.3
  • 35
    • 57849130395 scopus 로고    scopus 로고
    • Detection of microRNA expression in human peripheral blood microvesicles
    • Hunter MP, Ismail N, Zhang X, et al. Detection of microRNA expression in human peripheral blood microvesicles. PLoS One. 2008 ; 3 (11). e3694
    • (2008) PLoS One , vol.3 , Issue.11 , pp. 3694
    • Hunter, M.P.1    Ismail, N.2    Zhang, X.3
  • 36
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007 ; 9 (6). 654-659
    • (2007) Nat Cell Biol , vol.9 , Issue.6 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 37
    • 84893666749 scopus 로고    scopus 로고
    • Microvesicles as cell-cell messengers in cardiovascular diseases
    • Loyer X, Vion AC, Tedgui A, Boulanger CM. Microvesicles as cell-cell messengers in cardiovascular diseases. Circ Res. 2014 ; 114 (2). 345-353
    • (2014) Circ Res , vol.114 , Issue.2 , pp. 345-353
    • Loyer, X.1    Vion, A.C.2    Tedgui, A.3    Boulanger, C.M.4
  • 38
    • 77449127999 scopus 로고    scopus 로고
    • Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection
    • Zernecke A, Bidzhekov K, Noels H, et al. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci Signal. 2009 ; 2 (100). ra81
    • (2009) Sci Signal , vol.2 , Issue.100 , pp. 81
    • Zernecke, A.1    Bidzhekov, K.2    Noels, H.3
  • 39
    • 84887075238 scopus 로고    scopus 로고
    • Endothelial microparticle-mediated transfer of MicroRNA-126 promotes vascular endothelial cell repair via SPRED1 and is abrogated in glucose-damaged endothelial microparticles
    • Jansen F, Yang X, Hoelscher M, et al. Endothelial microparticle-mediated transfer of MicroRNA-126 promotes vascular endothelial cell repair via SPRED1 and is abrogated in glucose-damaged endothelial microparticles. Circulation. 2013 ; 128 (18). 2026-2038
    • (2013) Circulation , vol.128 , Issue.18 , pp. 2026-2038
    • Jansen, F.1    Yang, X.2    Hoelscher, M.3
  • 40
    • 84857708170 scopus 로고    scopus 로고
    • Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs
    • Hergenreider E, Heydt S, Treguer K, et al. Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs. Nat Cell Biol. 2012 ; 14 (3). 249-256
    • (2012) Nat Cell Biol , vol.14 , Issue.3 , pp. 249-256
    • Hergenreider, E.1    Heydt, S.2    Treguer, K.3
  • 41
    • 0032697942 scopus 로고    scopus 로고
    • A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides
    • Levin AA. A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochim Biophys Acta. 1999 ; 1489 (1). 69-84
    • (1999) Biochim Biophys Acta , vol.1489 , Issue.1 , pp. 69-84
    • Levin, A.A.1
  • 42
    • 80053567152 scopus 로고    scopus 로고
    • Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure
    • Montgomery RL, Hullinger TG, Semus HM, et al. Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure. Circulation. 2011 ; 124 (14). 1537-1547
    • (2011) Circulation , vol.124 , Issue.14 , pp. 1537-1547
    • Montgomery, R.L.1    Hullinger, T.G.2    Semus, H.M.3
  • 43
    • 84876759638 scopus 로고    scopus 로고
    • Dickkopf-1 (DKK1) phosphatase and tensin homolog on chromosome 10 (PTEN) crosstalk via microRNA interference in the diabetic heart
    • Ling S, Birnbaum Y, Nanhwan MK, et al. Dickkopf-1 (DKK1) phosphatase and tensin homolog on chromosome 10 (PTEN) crosstalk via microRNA interference in the diabetic heart. Basic Res Cardiol. 2013 ; 108 (3). 352
    • (2013) Basic Res Cardiol , vol.108 , Issue.3 , pp. 352
    • Ling, S.1    Birnbaum, Y.2    Nanhwan, M.K.3
  • 44
    • 84887199926 scopus 로고    scopus 로고
    • Modulation of microRNAs in hypertension-induced arterial remodeling through the beta1 and beta3-adrenoreceptor pathways
    • Ling S, Nanhwan M, Qian J, et al. Modulation of microRNAs in hypertension-induced arterial remodeling through the beta1 and beta3-adrenoreceptor pathways. J Mol Cell Cardiol. 2013 ; 65: 127-136
    • (2013) J Mol Cell Cardiol , vol.65 , pp. 127-136
    • Ling, S.1    Nanhwan, M.2    Qian, J.3
  • 45
    • 84876672015 scopus 로고    scopus 로고
    • Nebivolol induces distinct changes in profibrosis microRNA expression compared with atenolol, in salt-sensitive hypertensive rats
    • Ye H, Ling S, Castillo AC, et al. Nebivolol induces distinct changes in profibrosis microRNA expression compared with atenolol, in salt-sensitive hypertensive rats. Hypertension. 2013 ; 61 (5). 1008-1013
    • (2013) Hypertension , vol.61 , Issue.5 , pp. 1008-1013
    • Ye, H.1    Ling, S.2    Castillo, A.C.3
  • 46
    • 84880531657 scopus 로고    scopus 로고
    • MicroRNA-22 downregulation by atorvastatin in a mouse model of cardiac hypertrophy: A new mechanism for antihypertrophic intervention
    • Tu Y, Wan L, Bu L, et al. MicroRNA-22 downregulation by atorvastatin in a mouse model of cardiac hypertrophy: a new mechanism for antihypertrophic intervention. Cell Physiol Biochem. 2013 ; 31 (6). 997-1008
    • (2013) Cell Physiol Biochem , vol.31 , Issue.6 , pp. 997-1008
    • Tu, Y.1    Wan, L.2    Bu, L.3
  • 47
    • 84857491474 scopus 로고    scopus 로고
    • MicroRNA-21 blocks abdominal aortic aneurysm development and nicotineaugmented expansion
    • Maegdefessel L, Azuma J, Toh R, et al. MicroRNA-21 blocks abdominal aortic aneurysm development and nicotineaugmented expansion. Sci Transl Med. 2012 ; 4 ( 122 ):
    • (2012) Sci Transl Med , vol.4 , Issue.122
    • Maegdefessel, L.1    Azuma, J.2    Toh, R.3
  • 48
    • 84856552278 scopus 로고    scopus 로고
    • Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development
    • Maegdefessel L, Azuma J, Toh R, et al. Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development. J Clin Invest. 2012 ; 122 (2). 497-506
    • (2012) J Clin Invest , vol.122 , Issue.2 , pp. 497-506
    • Maegdefessel, L.1    Azuma, J.2    Toh, R.3
  • 49
    • 80051802344 scopus 로고    scopus 로고
    • MicroRNA-24 regulates vascularity after myocardial infarction
    • Fiedler J, Jazbutyte V, Kirchmaier BC, et al. MicroRNA-24 regulates vascularity after myocardial infarction. Circulation. 2011 ; 124 (6). 720-730
    • (2011) Circulation , vol.124 , Issue.6 , pp. 720-730
    • Fiedler, J.1    Jazbutyte, V.2    Kirchmaier, B.C.3
  • 50
    • 67649998366 scopus 로고    scopus 로고
    • MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice
    • Bonauer A, Carmona G, Iwasaki M, et al. MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice. Science. 2009 ; 324 (5935). 1710-1713
    • (2009) Science , vol.324 , Issue.5935 , pp. 1710-1713
    • Bonauer, A.1    Carmona, G.2    Iwasaki, M.3
  • 51
    • 84883654580 scopus 로고    scopus 로고
    • Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model
    • Hinkel R, Penzkofer D, Zuhlke S, et al. Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model. Circulation. 2013 ; 128 (10). 1066-1075
    • (2013) Circulation , vol.128 , Issue.10 , pp. 1066-1075
    • Hinkel, R.1    Penzkofer, D.2    Zuhlke, S.3
  • 52
    • 34147095310 scopus 로고    scopus 로고
    • The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2
    • Yang B, Lin H, Xiao J, et al. The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Nat Med. 2007 ; 13 (4). 486-491
    • (2007) Nat Med , vol.13 , Issue.4 , pp. 486-491
    • Yang, B.1    Lin, H.2    Xiao, J.3
  • 53
    • 78650701405 scopus 로고    scopus 로고
    • MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation
    • Lu Y, Zhang Y, Wang N, et al. MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation. Circulation. 2010 ; 122 (23). 2378-2387
    • (2010) Circulation , vol.122 , Issue.23 , pp. 2378-2387
    • Lu, Y.1    Zhang, Y.2    Wang, N.3
  • 54
    • 34250172419 scopus 로고    scopus 로고
    • MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation
    • Ji R, Cheng Y, Yue J, et al. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. Circ Res. 2007 ; 100 (11). 1579-1588
    • (2007) Circ Res , vol.100 , Issue.11 , pp. 1579-1588
    • Ji, R.1    Cheng, Y.2    Yue, J.3
  • 55
    • 80054971110 scopus 로고    scopus 로고
    • Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
    • Rayner KJ, Esau CC, Hussain FN, et al. Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides. Nature. 2011 ; 478 (7369). 404-407
    • (2011) Nature , vol.478 , Issue.7369 , pp. 404-407
    • Rayner, K.J.1    Esau, C.C.2    Hussain, F.N.3
  • 56
    • 79960015327 scopus 로고    scopus 로고
    • Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
    • Rayner KJ, Sheedy FJ, Esau CC, et al. Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J Clin Invest. 2011 ; 121 (7). 2921-2931
    • (2011) J Clin Invest , vol.121 , Issue.7 , pp. 2921-2931
    • Rayner, K.J.1    Sheedy, F.J.2    Esau, C.C.3
  • 57
    • 40249106014 scopus 로고    scopus 로고
    • Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver
    • Elmen J, Lindow M, Silahtaroglu A, et al. Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res. 2008 ; 36 (4). 1153-1162
    • (2008) Nucleic Acids Res , vol.36 , Issue.4 , pp. 1153-1162
    • Elmen, J.1    Lindow, M.2    Silahtaroglu, A.3
  • 58
    • 42249093319 scopus 로고    scopus 로고
    • LNA-mediated microRNA silencing in non-human primates
    • Elmen J, Lindow M, Schutz S, et al. LNA-mediated microRNA silencing in non-human primates. Nature. 2008 ; 452 (7189). 896-899
    • (2008) Nature , vol.452 , Issue.7189 , pp. 896-899
    • Elmen, J.1    Lindow, M.2    Schutz, S.3
  • 59
    • 84880031381 scopus 로고    scopus 로고
    • Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144
    • Ramirez CM, Rotllan N, Vlassov AV, et al. Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144. Circ Res. 2013 ; 112 (12). 1592-1601
    • (2013) Circ Res , vol.112 , Issue.12 , pp. 1592-1601
    • Ramirez, C.M.1    Rotllan, N.2    Vlassov, A.V.3
  • 60
    • 84866464706 scopus 로고    scopus 로고
    • MicroRNA-145 targeted therapy reduces atherosclerosis
    • Lovren F, Pan Y, Quan A, et al. MicroRNA-145 targeted therapy reduces atherosclerosis. Circulation. 2012 ; 126: S81 - S90
    • (2012) Circulation , vol.126 , pp. 81-S90
    • Lovren, F.1    Pan, Y.2    Quan, A.3
  • 61
    • 84861642380 scopus 로고    scopus 로고
    • MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes
    • Jayawardena TM, Egemnazarov B, Finch EA, et al. MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. Circ Res. 2012 ; 110 (11). 1465-1473
    • (2012) Circ Res , vol.110 , Issue.11 , pp. 1465-1473
    • Jayawardena, T.M.1    Egemnazarov, B.2    Finch, E.A.3
  • 62
    • 79953881831 scopus 로고    scopus 로고
    • Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency
    • Anokye-Danso F, Trivedi CM, Juhr D, et al. Highly efficient miRNA-mediated reprogramming of mouse and human somatic cells to pluripotency. Cell Stem Cell. 2011 ; 8 (4). 376-388
    • (2011) Cell Stem Cell , vol.8 , Issue.4 , pp. 376-388
    • Anokye-Danso, F.1    Trivedi, C.M.2    Juhr, D.3
  • 63
    • 84863114983 scopus 로고    scopus 로고
    • Role of miR-21 in the pathogenesis of atrial fibrosis
    • Adam O, Lohfelm B, Thum T, et al. Role of miR-21 in the pathogenesis of atrial fibrosis. Basic Res Cardiol. 2012 ; 107 (5). 278
    • (2012) Basic Res Cardiol , vol.107 , Issue.5 , pp. 278
    • Adam, O.1    Lohfelm, B.2    Thum, T.3
  • 64
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T, Gross C, Fiedler J, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature. 2008 ; 456 (7224). 980-984
    • (2008) Nature , vol.456 , Issue.7224 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3
  • 65
    • 84857791711 scopus 로고    scopus 로고
    • Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice
    • Wang J, Song Y, Zhang Y, et al. Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice. Cell Res. 2012 ; 22 (3). 516-527
    • (2012) Cell Res , vol.22 , Issue.3 , pp. 516-527
    • Wang, J.1    Song, Y.2    Zhang, Y.3
  • 66
    • 84867903854 scopus 로고    scopus 로고
    • Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
    • Bernardo BC, Gao XM, Winbanks CE, et al. Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function. Proc Natl Acad Sci USA. 2012 ; 109 (43). 17615-17620
    • (2012) Proc Natl Acad Sci USA , vol.109 , Issue.43 , pp. 17615-17620
    • Bernardo, B.C.1    Gao, X.M.2    Winbanks, C.E.3
  • 67
    • 84874700585 scopus 로고    scopus 로고
    • MicroRNA-34a regulates cardiac ageing and function
    • Boon RA, Iekushi K, Lechner S, et al. MicroRNA-34a regulates cardiac ageing and function. Nature. 2013 ; 495 (7439). 107-110
    • (2013) Nature , vol.495 , Issue.7439 , pp. 107-110
    • Boon, R.A.1    Iekushi, K.2    Lechner, S.3
  • 68
    • 84865206803 scopus 로고    scopus 로고
    • MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-beta1 pathway
    • Pan Z, Sun X, Shan H, et al. MicroRNA-101 inhibited postinfarct cardiac fibrosis and improved left ventricular compliance via the FBJ osteosarcoma oncogene/transforming growth factor-beta1 pathway. Circulation. 2012 ; 126 (7). 840-850
    • (2012) Circulation , vol.126 , Issue.7 , pp. 840-850
    • Pan, Z.1    Sun, X.2    Shan, H.3
  • 69
    • 84867009927 scopus 로고    scopus 로고
    • The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy
    • Ucar A, Gupta SK, Fiedler J, et al. The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy. Nat Commun. 2012 ; 3: 1078
    • (2012) Nat Commun , vol.3 , pp. 1078
    • Ucar, A.1    Gupta, S.K.2    Fiedler, J.3
  • 70
    • 34249279050 scopus 로고    scopus 로고
    • MicroRNA-133 controls cardiac hypertrophy
    • Care A, Catalucci D, Felicetti F, et al. MicroRNA-133 controls cardiac hypertrophy. Nat Med. 2007 ; 13 (5). 613-618
    • (2007) Nat Med , vol.13 , Issue.5 , pp. 613-618
    • Care, A.1    Catalucci, D.2    Felicetti, F.3
  • 71
    • 78649843756 scopus 로고    scopus 로고
    • MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling
    • da Costa Martins PA, Salic K, Gladka MM, et al. MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling. Nat Cell Biol. 2010 ; 12 (12). 1220-1227
    • (2010) Nat Cell Biol , vol.12 , Issue.12 , pp. 1220-1227
    • Da Costa Martins, P.A.1    Salic, K.2    Gladka, M.M.3
  • 72
    • 84878294979 scopus 로고    scopus 로고
    • MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors
    • Ganesan J, Ramanujam D, Sassi Y, et al. MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors. Circulation. 2013 ; 127 (21). 2097-2106
    • (2013) Circulation , vol.127 , Issue.21 , pp. 2097-2106
    • Ganesan, J.1    Ramanujam, D.2    Sassi, Y.3
  • 73
    • 84885152873 scopus 로고    scopus 로고
    • MiR-17 targets tissue inhibitor of metalloproteinase 1 and 2 to modulate cardiac matrix remodeling
    • Li SH, Guo J. Wu J, et al. miR-17 targets tissue inhibitor of metalloproteinase 1 and 2 to modulate cardiac matrix remodeling. FASEB J. 2013 ; 27 (10). 4254-4265
    • (2013) FASEB J , vol.27 , Issue.10 , pp. 4254-4265
    • Li, S.H.1    Guo, J.2    Wu, J.3
  • 74
    • 84865439215 scopus 로고    scopus 로고
    • MicroRNA-24 regulates cardiac fibrosis after myocardial infarction
    • Wang J, Huang W, Xu R, et al. MicroRNA-24 regulates cardiac fibrosis after myocardial infarction. J Cell Mol Med. 2012 ; 16 (9). 2150-2160
    • (2012) J Cell Mol Med , vol.16 , Issue.9 , pp. 2150-2160
    • Wang, J.1    Huang, W.2    Xu, R.3
  • 75
    • 77954766181 scopus 로고    scopus 로고
    • Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury
    • Ye Y, Hu Z, Lin Y, Zhang C, Perez-Polo JR. Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury. Cardiovasc Res. 2010 ; 87 (3). 535-544
    • (2010) Cardiovasc Res , vol.87 , Issue.3 , pp. 535-544
    • Ye, Y.1    Hu, Z.2    Lin, Y.3    Zhang, C.4    Perez-Polo, J.R.5
  • 76
    • 84900564532 scopus 로고    scopus 로고
    • Overexpression of microRNA-99a attenuates heart remodelling and improves cardiac performance after myocardial infarction
    • Li Q, Xie J, Li R, et al. Overexpression of microRNA-99a attenuates heart remodelling and improves cardiac performance after myocardial infarction. J Cell Mol Med. 2014 ; 18 (5). 919-928
    • (2014) J Cell Mol Med , vol.18 , Issue.5 , pp. 919-928
    • Li, Q.1    Xie, J.2    Li, R.3
  • 77
    • 84889069477 scopus 로고    scopus 로고
    • Role of miR-145 in cardiac myofibroblast differentiation
    • Wang YS, Li SH, Guo J, et al. Role of miR-145 in cardiac myofibroblast differentiation. J Mol Cell Cardiol. 2014 ; 66: 94-105
    • (2014) J Mol Cell Cardiol , vol.66 , pp. 94-105
    • Wang, Y.S.1    Li, S.H.2    Guo, J.3
  • 78
    • 77957243894 scopus 로고    scopus 로고
    • MicroRNA-210 as a novel therapy for treatment of ischemic heart disease
    • Hu S, Huang M, Li Z, et al. MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation. 2010 ; 122 (11 suppl). S124 - S131
    • (2010) Circulation , vol.122 , Issue.11 , pp. S124-S131
    • Hu, S.1    Huang, M.2    Li, Z.3
  • 79
    • 66349123063 scopus 로고    scopus 로고
    • MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20
    • Ren XP, Wu J, Wang X, et al. MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20. Circulation. 2009 ; 119 (17). 2357-2366
    • (2009) Circulation , vol.119 , Issue.17 , pp. 2357-2366
    • Ren, X.P.1    Wu, J.2    Wang, X.3
  • 80
    • 84857379176 scopus 로고    scopus 로고
    • Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension
    • Pullamsetti SS, Doebele C, Fischer A, et al. Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension. Am J Respir Crit Care Med. 2012 ; 185 (4). 409-419
    • (2012) Am J Respir Crit Care Med , vol.185 , Issue.4 , pp. 409-419
    • Pullamsetti, S.S.1    Doebele, C.2    Fischer, A.3
  • 81
    • 68049083397 scopus 로고    scopus 로고
    • MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation
    • Cheng Y, Liu X, Yang J, et al. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ Res. 2009 ; 105 (2). 158-166
    • (2009) Circ Res , vol.105 , Issue.2 , pp. 158-166
    • Cheng, Y.1    Liu, X.2    Yang, J.3
  • 82
    • 84880748603 scopus 로고    scopus 로고
    • Pathological ventricular remodeling: Mechanisms: Part 1 of 2
    • Burchfield JS, Xie M, Hill JA. Pathological ventricular remodeling: mechanisms: part 1 of 2. Circulation. 2013 ; 128 (4). 388-400
    • (2013) Circulation , vol.128 , Issue.4 , pp. 388-400
    • Burchfield, J.S.1    Xie, M.2    Hill, J.A.3
  • 84
    • 79957888881 scopus 로고    scopus 로고
    • Pivotal role of cardiomyocyte TGF-beta signaling in the murine pathological response to sustained pressure overload
    • Koitabashi N, Danner T, Zaiman AL, et al. Pivotal role of cardiomyocyte TGF-beta signaling in the murine pathological response to sustained pressure overload. J Clin Invest. 2011 ; 121 (6). 2301-2312
    • (2011) J Clin Invest , vol.121 , Issue.6 , pp. 2301-2312
    • Koitabashi, N.1    Danner, T.2    Zaiman, A.L.3
  • 85
    • 84892924162 scopus 로고    scopus 로고
    • Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: Analysis of recurrent cardiovascular events and mortality
    • Zsebo K, Yaroshinsky A, Rudy JJ, et al. Long-term effects of AAV1/SERCA2a gene transfer in patients with severe heart failure: analysis of recurrent cardiovascular events and mortality. Circ Res. 2014 ; 114 (1). 101-108
    • (2014) Circ Res , vol.114 , Issue.1 , pp. 101-108
    • Zsebo, K.1    Yaroshinsky, A.2    Rudy, J.J.3
  • 86
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006 ; 126 (4). 663-676
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 87
    • 78649443533 scopus 로고    scopus 로고
    • Induced pluripotent stem cells: Developmental biology to regenerative medicine
    • Nelson TJ, Martinez-Fernandez A, Terzic A. Induced pluripotent stem cells: developmental biology to regenerative medicine. Nat Rev Cardiol. 2010 ; 7 (12). 700-710
    • (2010) Nat Rev Cardiol , vol.7 , Issue.12 , pp. 700-710
    • Nelson, T.J.1    Martinez-Fernandez, A.2    Terzic, A.3
  • 88
    • 66149160608 scopus 로고    scopus 로고
    • Embryonic stem cell-specific microRNAs promote induced pluripotency
    • Judson RL, Babiarz JE, Venere M, Blelloch R. Embryonic stem cell-specific microRNAs promote induced pluripotency. Nat Biotechnol. 2009 ; 27 (5). 459-461
    • (2009) Nat Biotechnol , vol.27 , Issue.5 , pp. 459-461
    • Judson, R.L.1    Babiarz, J.E.2    Venere, M.3    Blelloch, R.4
  • 89
    • 84875848994 scopus 로고    scopus 로고
    • Reprogramming of human fibroblasts toward a cardiac fate
    • Nam YJ, Song K, Luo X, et al. Reprogramming of human fibroblasts toward a cardiac fate. Proc Natl Acad Sci USA. 2013 ; 110 (14). 5588-5593
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.14 , pp. 5588-5593
    • Nam, Y.J.1    Song, K.2    Luo, X.3
  • 90
    • 79957855295 scopus 로고    scopus 로고
    • Induced pluripotent stem cells - A cautionary note
    • Mummery C. Induced pluripotent stem cells - a cautionary note. N Engl J Med. 2011 ; 364 (22). 2160-2162
    • (2011) N Engl J Med , vol.364 , Issue.22 , pp. 2160-2162
    • Mummery, C.1
  • 91
    • 79955512050 scopus 로고    scopus 로고
    • Stem and progenitor cell-based therapy in ischaemic heart disease: Promise, uncertainties, and challenges
    • Tongers J, Losordo DW, Landmesser U. Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges. Eur Heart J. 2011 ; 32 (10). 1197-1206
    • (2011) Eur Heart J , vol.32 , Issue.10 , pp. 1197-1206
    • Tongers, J.1    Losordo, D.W.2    Landmesser, U.3
  • 92
    • 84860157611 scopus 로고    scopus 로고
    • Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1
    • Wang X, Zhu H, Zhang X, et al. Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1. Cardiovasc Res. 2012 ; 94 (2). 379-390
    • (2012) Cardiovasc Res , vol.94 , Issue.2 , pp. 379-390
    • Wang, X.1    Zhu, H.2    Zhang, X.3
  • 93
    • 84904335129 scopus 로고    scopus 로고
    • MicroRNAs associated with ischemia-reperfusion injury and cardioprotection by ischemic pre- and postconditioning: ProtectomiRs
    • Varga ZV, Zvara A, Farago N, et al. MicroRNAs associated with ischemia-reperfusion injury and cardioprotection by ischemic pre- and postconditioning: protectomiRs. Am J Physiol Heart Circ Physiol. 2014 ; 307 (2). H216 - H227
    • (2014) Am J Physiol Heart Circ Physiol , vol.307 , Issue.2 , pp. 216-H227
    • Varga, Z.V.1    Zvara, A.2    Farago, N.3
  • 94
    • 80051534224 scopus 로고    scopus 로고
    • Remote ischemic preconditioning: Current knowledge, unresolved questions, and future priorities
    • Przyklenk K, Whittaker P. Remote ischemic preconditioning: current knowledge, unresolved questions, and future priorities. J Cardiovasc Pharmacol Ther. 2011 ; 16 (3-4). 255-259
    • (2011) J Cardiovasc Pharmacol Ther , vol.16 , Issue.34 , pp. 255-259
    • Przyklenk, K.1    Whittaker, P.2
  • 95
    • 84895930344 scopus 로고    scopus 로고
    • Remote ischemic preconditioning preserves mitochondrial function and influences myocardial microRNA expression in atrial myocardium during coronary bypass surgery
    • Slagsvold KH, Rognmo O, Hoydal M, Wisloff U, Wahba A. Remote ischemic preconditioning preserves mitochondrial function and influences myocardial microRNA expression in atrial myocardium during coronary bypass surgery. Circ Res. 2014 ; 114 (5). 851-859
    • (2014) Circ Res , vol.114 , Issue.5 , pp. 851-859
    • Slagsvold, K.H.1    Rognmo, O.2    Hoydal, M.3    Wisloff, U.4    Wahba, A.5
  • 96
    • 84862180384 scopus 로고    scopus 로고
    • Expression of microRNA-1 and microRNA-21 in different protocols of ischemic conditioning in an isolated rat heart model
    • Duan X, Ji B, Wang X, et al. Expression of microRNA-1 and microRNA-21 in different protocols of ischemic conditioning in an isolated rat heart model. Cardiology. 2012 ; 122 (1). 36-43
    • (2012) Cardiology , vol.122 , Issue.1 , pp. 36-43
    • Duan, X.1    Ji, B.2    Wang, X.3
  • 97
    • 84897970506 scopus 로고    scopus 로고
    • Lichtenstein AH, et al. 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • Stone NJ, Robinson J. Lichtenstein AH, et al. 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014 ; 129: S1 - S45
    • (2014) Circulation , vol.129 , pp. 1-S45
    • Stone, N.J.1    Robinson, J.2
  • 99
    • 77955059593 scopus 로고    scopus 로고
    • MicroRNAs in arterial remodelling, inflammation and atherosclerosis
    • Weber C, Schober A, Zernecke A. MicroRNAs in arterial remodelling, inflammation and atherosclerosis. Curr Drug Targets. 2010 ; 11 (8). 950-956
    • (2010) Curr Drug Targets , vol.11 , Issue.8 , pp. 950-956
    • Weber, C.1    Schober, A.2    Zernecke, A.3
  • 101
    • 84898419690 scopus 로고    scopus 로고
    • MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1
    • Schober A, Nazari-Jahantigh M, Wei Y, et al. MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1. Nat Med. 2014 ; 20 (4). 368-376
    • (2014) Nat Med , vol.20 , Issue.4 , pp. 368-376
    • Schober, A.1    Nazari-Jahantigh, M.2    Wei, Y.3
  • 102
    • 84894196759 scopus 로고    scopus 로고
    • Inhibition of microRNA-92a prevents endothelial dysfunction and atherosclerosis in mice
    • Loyer X, Potteaux S, Vion AC, et al. Inhibition of microRNA-92a prevents endothelial dysfunction and atherosclerosis in mice. Circ Res. 2014 ; 114 (3). 434-443
    • (2014) Circ Res , vol.114 , Issue.3 , pp. 434-443
    • Loyer, X.1    Potteaux, S.2    Vion, A.C.3
  • 103
    • 84892908098 scopus 로고    scopus 로고
    • Systemic delivery of microRNA-181b inhibits nuclear factor-kappaB activation, vascular inflammation, and atherosclerosis in apolipoprotein E-deficient mice
    • Sun X, He S, Wara AK, et al. Systemic delivery of microRNA-181b inhibits nuclear factor-kappaB activation, vascular inflammation, and atherosclerosis in apolipoprotein E-deficient mice. Circ Res. 2014 ; 114 (1). 32-40
    • (2014) Circ Res , vol.114 , Issue.1 , pp. 32-40
    • Sun, X.1    He, S.2    Wara, A.K.3
  • 104
    • 84884814430 scopus 로고    scopus 로고
    • Targeting smooth muscle microRNAs for therapeutic benefit in vascular disease
    • Albinsson S, Sward K. Targeting smooth muscle microRNAs for therapeutic benefit in vascular disease. Pharmacol Res. 2013 ; 75: 28-36
    • (2013) Pharmacol Res , vol.75 , pp. 28-36
    • Albinsson, S.1    Sward, K.2
  • 106
    • 84864773072 scopus 로고    scopus 로고
    • MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
    • Tsai WC, Hsu SD, Hsu CS, et al. MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. J Clin Invest. 2012 ; 122 (8). 2884-2897
    • (2012) J Clin Invest , vol.122 , Issue.8 , pp. 2884-2897
    • Tsai, W.C.1    Hsu, S.D.2    Hsu, C.S.3
  • 107
    • 84864761391 scopus 로고    scopus 로고
    • Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
    • Hsu SH, Wang B, Kota J, et al. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest. 2012 ; 122 (8). 2871-2883
    • (2012) J Clin Invest , vol.122 , Issue.8 , pp. 2871-2883
    • Hsu, S.H.1    Wang, B.2    Kota, J.3
  • 108
    • 77955456415 scopus 로고    scopus 로고
    • MiR-33 links SREBP-2 induction to repression of sterol transporters
    • Marquart TJ, Allen RM, Ory DS. Baldan A. miR-33 links SREBP-2 induction to repression of sterol transporters. Proc Natl Acad Sci USA. 2010 ; 107 (27). 12228-12232
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.27 , pp. 12228-12232
    • Marquart, T.J.1    Allen, R.M.2    Ory, D.S.3    Baldan, A.4
  • 109
    • 77953780835 scopus 로고    scopus 로고
    • MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis
    • Najafi-Shoushtari SH, Kristo F, Li Y, et al. MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis. Science. 2010 ; 328 (5985). 1566-1569
    • (2010) Science , vol.328 , Issue.5985 , pp. 1566-1569
    • Najafi-Shoushtari, S.H.1    Kristo, F.2    Li, Y.3
  • 110
    • 84881029988 scopus 로고    scopus 로고
    • Therapeutic silencing of microRNA-33 inhibits the progression of atherosclerosis in Ldlr-/- mice - Brief report
    • Rotllan N, Ramirez CM, Aryal B, Esau CC, Fernandez-Hernando C. Therapeutic silencing of microRNA-33 inhibits the progression of atherosclerosis in Ldlr-/- mice - brief report. Arterioscler Thromb Vasc Biol. 2013 ; 33 (8). 1973-1977
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.8 , pp. 1973-1977
    • Rotllan, N.1    Ramirez, C.M.2    Aryal, B.3    Esau, C.C.4    Fernandez-Hernando, C.5
  • 111
    • 84874361381 scopus 로고    scopus 로고
    • Anti-miR-33 therapy does not alter the progression of atherosclerosis in low-density lipoprotein receptor-deficient mice
    • Marquart TJ, Wu J, Lusis AJ, Baldan A. Anti-miR-33 therapy does not alter the progression of atherosclerosis in low-density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2013 ; 33 (3). 455-458
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , Issue.3 , pp. 455-458
    • Marquart, T.J.1    Wu, J.2    Lusis, A.J.3    Baldan, A.4
  • 112
    • 84876359742 scopus 로고    scopus 로고
    • MicroRNA regulation of cardiac conduction and arrhythmias
    • Kim GH. MicroRNA regulation of cardiac conduction and arrhythmias. Transl Res. 2013 ; 161 (5). 381-392
    • (2013) Transl Res , vol.161 , Issue.5 , pp. 381-392
    • Kim, G.H.1
  • 113
    • 77956938644 scopus 로고    scopus 로고
    • MicroRNAs and cardiac conduction
    • Latronico MV, Condorelli G. MicroRNAs and cardiac conduction. Curr Drug Targets. 2010 ; 11 (8). 907-912
    • (2010) Curr Drug Targets , vol.11 , Issue.8 , pp. 907-912
    • Latronico, M.V.1    Condorelli, G.2
  • 114
    • 52449122650 scopus 로고    scopus 로고
    • Control of cardiac excitability by microRNAs
    • Yang B, Lu Y, Wang Z. Control of cardiac excitability by microRNAs. Cardiovasc Res. 2008 ; 79 (4). 571-580
    • (2008) Cardiovasc Res , vol.79 , Issue.4 , pp. 571-580
    • Yang, B.1    Lu, Y.2    Wang, Z.3
  • 115
    • 79951863579 scopus 로고    scopus 로고
    • MicroRNAs and atrial fibrillation: New fundamentals
    • Wang Z, Lu Y, Yang B. MicroRNAs and atrial fibrillation: new fundamentals. Cardiovasc Res. 2011 ; 89 (4). 710-721
    • (2011) Cardiovasc Res , vol.89 , Issue.4 , pp. 710-721
    • Wang, Z.1    Lu, Y.2    Yang, B.3
  • 116
    • 34347376692 scopus 로고    scopus 로고
    • Characterization of microRNA expression profiles in normal human tissues
    • Liang Y, Ridzon D, Wong L, Chen C. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics. 2007 ; 8: 166
    • (2007) BMC Genomics , vol.8 , pp. 166
    • Liang, Y.1    Ridzon, D.2    Wong, L.3    Chen, C.4
  • 117
    • 70549111002 scopus 로고    scopus 로고
    • Changes in microRNA-1 expression and IK1 up-regulation in human atrial fibrillation
    • Girmatsion Z, Biliczki P, Bonauer A, et al. Changes in microRNA-1 expression and IK1 up-regulation in human atrial fibrillation. Heart Rhythm. 2009 ; 6 (12). 1802-1809
    • (2009) Heart Rhythm , vol.6 , Issue.12 , pp. 1802-1809
    • Girmatsion, Z.1    Biliczki, P.2    Bonauer, A.3
  • 118
    • 84864229176 scopus 로고    scopus 로고
    • A role for miR-145 in pulmonary arterial hypertension: Evidence from mouse models and patient samples
    • Caruso P, Dempsie Y, Stevens HC, et al. A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples. Circ Res. 2012 ; 111 (3). 290-300
    • (2012) Circ Res , vol.111 , Issue.3 , pp. 290-300
    • Caruso, P.1    Dempsie, Y.2    Stevens, H.C.3
  • 119
    • 80255137053 scopus 로고    scopus 로고
    • MicroRNA-29 in aortic dilation: Implications for aneurysm formation
    • Boon RA, Seeger T, Heydt S, et al. MicroRNA-29 in aortic dilation: implications for aneurysm formation. Circ Res. 2011 ; 109 (10). 1115-1119
    • (2011) Circ Res , vol.109 , Issue.10 , pp. 1115-1119
    • Boon, R.A.1    Seeger, T.2    Heydt, S.3
  • 120
    • 84863419727 scopus 로고    scopus 로고
    • Selective microRNA suppression in human thoracic aneurysms: Relationship of miR-29a to aortic size and proteolytic induction
    • Jones JA, Stroud RE, O'Quinn EC, et al. Selective microRNA suppression in human thoracic aneurysms: relationship of miR-29a to aortic size and proteolytic induction. Circ Cardiovasc Genet. 2011 ; 4 (6). 605-613
    • (2011) Circ Cardiovasc Genet , vol.4 , Issue.6 , pp. 605-613
    • Jones, J.A.1    Stroud, R.E.2    O'Quinn, E.C.3
  • 121
    • 58649087374 scopus 로고    scopus 로고
    • MiR-21: A small multi-faceted RNA
    • Krichevsky AM. Gabriely G. miR-21: a small multi-faceted RNA. J Cell Mol Med. 2009 ; 13 (1). 39-53
    • (2009) J Cell Mol Med , vol.13 , Issue.1 , pp. 39-53
    • Krichevsky, A.M.1    Gabriely, G.2
  • 122
    • 84883225689 scopus 로고    scopus 로고
    • Molecular imaging strategies for in vivo tracking of microRNAs: A comprehensive review
    • Hernandez R, Orbay H, Cai W. Molecular imaging strategies for in vivo tracking of microRNAs: a comprehensive review. Curr Med Chem. 2013 ; 20 (29). 3594-3603
    • (2013) Curr Med Chem , vol.20 , Issue.29 , pp. 3594-3603
    • Hernandez, R.1    Orbay, H.2    Cai, W.3
  • 123
    • 84877258007 scopus 로고    scopus 로고
    • Treatment of HCV infection by targeting microRNA
    • Janssen HL, Reesink HW, Lawitz EJ, et al. Treatment of HCV infection by targeting microRNA. N Engl J Med. 2013 ; 368 (18). 1685-1694
    • (2013) N Engl J Med , vol.368 , Issue.18 , pp. 1685-1694
    • Janssen, H.L.1    Reesink, H.W.2    Lawitz, E.J.3
  • 124
    • 84886799951 scopus 로고    scopus 로고
    • Targeting sarcoplasmic reticulum calcium ATPase by gene therapy
    • Gwathmey JK, Yerevanian A, Hajjar RJ. Targeting sarcoplasmic reticulum calcium ATPase by gene therapy. Hum Gene Ther. 2013 ; 24 (11). 937-947
    • (2013) Hum Gene Ther , vol.24 , Issue.11 , pp. 937-947
    • Gwathmey, J.K.1    Yerevanian, A.2    Hajjar, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.