메뉴 건너뛰기




Volumn 75, Issue , 2013, Pages 28-36

Targeting smooth muscle microRNAs for therapeutic benefit in vascular disease

Author keywords

Aneurysm; Atherosclerosis; MicroRNA; Neointimal hyperplasia; Pulmonary arterial hypertension; Vascular smooth muscle

Indexed keywords

CARDIOVASCULAR AGENT; KRUPPEL LIKE FACTOR 4; MICRORNA; MICRORNA 1; MICRORNA 133; MICRORNA 143; MICRORNA 145; MICRORNA 145 ANTIBODY; MICRORNA 145A; MICRORNA 145A INHIBITOR; MICRORNA 17; MICRORNA 200B; MICRORNA 21; MICRORNA 221; MICRORNA 29; MICRORNA 328; UNCLASSIFIED DRUG;

EID: 84884814430     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2013.04.003     Document Type: Review
Times cited : (55)

References (112)
  • 2
    • 79955768576 scopus 로고    scopus 로고
    • Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality
    • Y. Pan, L. Balazs, G. Tigyi, and J. Yue Conditional deletion of Dicer in vascular smooth muscle cells leads to the developmental delay and embryonic mortality Biochemical and Biophysical Research Communications 408 2011 369 374
    • (2011) Biochemical and Biophysical Research Communications , vol.408 , pp. 369-374
    • Pan, Y.1    Balazs, L.2    Tigyi, G.3    Yue, J.4
  • 3
    • 84861723998 scopus 로고    scopus 로고
    • MicroRNAs are essential for stretch-induced vascular smooth muscle contractile differentiation via microRNA (miR)-145-dependent expression of L-type calcium channels
    • K.M. Turczynska, M.K. Sadegh, P. Hellstrand, K. Sward, and S. Albinsson MicroRNAs are essential for stretch-induced vascular smooth muscle contractile differentiation via microRNA (miR)-145-dependent expression of L-type calcium channels Journal of Biological Chemistry 287 2012 19199 19206
    • (2012) Journal of Biological Chemistry , vol.287 , pp. 19199-19206
    • Turczynska, K.M.1    Sadegh, M.K.2    Hellstrand, P.3    Sward, K.4    Albinsson, S.5
  • 4
    • 84860464993 scopus 로고    scopus 로고
    • Deletion of dicer in smooth muscle affects voiding pattern and reduces detrusor contractility and neuroeffector transmission
    • M.K. Sadegh, M. Ekman, C. Rippe, B. Uvelius, K. Sward, and S. Albinsson Deletion of dicer in smooth muscle affects voiding pattern and reduces detrusor contractility and neuroeffector transmission PLoS ONE 7 2012 e35882
    • (2012) PLoS ONE , vol.7 , pp. 35882
    • Sadegh, M.K.1    Ekman, M.2    Rippe, C.3    Uvelius, B.4    Sward, K.5    Albinsson, S.6
  • 5
    • 79955547741 scopus 로고    scopus 로고
    • Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function
    • S. Albinsson, A. Skoura, J. Yu, A. Dilorenzo, C. Fernandez-Hernando, and S. Offermanns Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function PLoS ONE 6 2011 e18869
    • (2011) PLoS ONE , vol.6 , pp. 18869
    • Albinsson, S.1    Skoura, A.2    Yu, J.3    Dilorenzo, A.4    Fernandez-Hernando, C.5    Offermanns, S.6
  • 6
    • 79955038937 scopus 로고    scopus 로고
    • MicroRNAs dynamically remodel gastrointestinal smooth muscle cells
    • C. Park, W. Yan, S.M. Ward, S.J. Hwang, Q. Wu, and W.J. Hatton MicroRNAs dynamically remodel gastrointestinal smooth muscle cells PLoS ONE 6 2011 e18628
    • (2011) PLoS ONE , vol.6 , pp. 18628
    • Park, C.1    Yan, W.2    Ward, S.M.3    Hwang, S.J.4    Wu, Q.5    Hatton, W.J.6
  • 7
    • 70349213385 scopus 로고    scopus 로고
    • Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster
    • T. Boettger, N. Beetz, S. Kostin, J. Schneider, M. Kruger, and L. Hein Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster Journal of Clinical Investigation 119 2009 2634 2647
    • (2009) Journal of Clinical Investigation , vol.119 , pp. 2634-2647
    • Boettger, T.1    Beetz, N.2    Kostin, S.3    Schneider, J.4    Kruger, M.5    Hein, L.6
  • 9
    • 70449701464 scopus 로고    scopus 로고
    • The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: Correlates with human disease
    • L. Elia, M. Quintavalle, J. Zhang, R. Contu, L. Cossu, and M.V. Latronico The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease Cell Death and Differentiation 16 2009 1590 1598
    • (2009) Cell Death and Differentiation , vol.16 , pp. 1590-1598
    • Elia, L.1    Quintavalle, M.2    Zhang, J.3    Contu, R.4    Cossu, L.5    Latronico, M.V.6
  • 10
    • 70349125875 scopus 로고    scopus 로고
    • MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury
    • M. Xin, E.M. Small, L.B. Sutherland, X. Qi, J. McAnally, and C.F. Plato MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury Genes and Development 23 2009 2166 2178
    • (2009) Genes and Development , vol.23 , pp. 2166-2178
    • Xin, M.1    Small, E.M.2    Sutherland, L.B.3    Qi, X.4    McAnally, J.5    Plato, C.F.6
  • 11
    • 77950564432 scopus 로고    scopus 로고
    • MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro
    • M. Quintavalle, L. Elia, G. Condorelli, and S.A. Courtneidge MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro Journal of Cell Biology 189 2010 13 22
    • (2010) Journal of Cell Biology , vol.189 , pp. 13-22
    • Quintavalle, M.1    Elia, L.2    Condorelli, G.3    Courtneidge, S.A.4
  • 13
    • 48549106378 scopus 로고    scopus 로고
    • The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis
    • S. Wang, A.B. Aurora, B.A. Johnson, X. Qi, J. McAnally, and J.A. Hill The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis Developmental Cell 15 2008 261 271
    • (2008) Developmental Cell , vol.15 , pp. 261-271
    • Wang, S.1    Aurora, A.B.2    Johnson, B.A.3    Qi, X.4    McAnally, J.5    Hill, J.A.6
  • 14
    • 79953204259 scopus 로고    scopus 로고
    • Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
    • H. Schunkert, I.R. Konig, S. Kathiresan, M.P. Reilly, T.L. Assimes, and H. Holm Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease Nature Genetics 43 2011 333 338
    • (2011) Nature Genetics , vol.43 , pp. 333-338
    • Schunkert, H.1    Konig, I.R.2    Kathiresan, S.3    Reilly, M.P.4    Assimes, T.L.5    Holm, H.6
  • 15
    • 33645075443 scopus 로고    scopus 로고
    • MiR-122 regulation of lipid metabolism revealed by in vivo antisense targeting
    • C. Esau, S. Davis, S.F. Murray, X.X. Yu, S.K. Pandey, and M. Pear miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting Cell Metabolism 3 2006 87 98
    • (2006) Cell Metabolism , vol.3 , pp. 87-98
    • Esau, C.1    Davis, S.2    Murray, S.F.3    Yu, X.X.4    Pandey, S.K.5    Pear, M.6
  • 20
    • 67649349865 scopus 로고    scopus 로고
    • MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages
    • T. Chen, Z. Huang, L. Wang, Y. Wang, F. Wu, and S. Meng MicroRNA-125a-5p partly regulates the inflammatory response, lipid uptake, and ORP9 expression in oxLDL-stimulated monocyte/macrophages Cardiovascular Research 83 2009 131 139
    • (2009) Cardiovascular Research , vol.83 , pp. 131-139
    • Chen, T.1    Huang, Z.2    Wang, L.3    Wang, Y.4    Wu, F.5    Meng, S.6
  • 23
    • 42149107512 scopus 로고    scopus 로고
    • Role of smooth muscle cells in the initiation and early progression of atherosclerosis
    • DOI 10.1161/ATVBAHA.107.159327, PII 0004360520080500000007
    • A.C. Doran, N. Meller, and C.A. McNamara Role of smooth muscle cells in the initiation and early progression of atherosclerosis Arteriosclerosis, Thrombosis, and Vascular Biology 28 2008 812 819 (Pubitemid 351544093)
    • (2008) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.28 , Issue.5 , pp. 812-819
    • Doran, A.C.1    Meller, N.2    McNamara, C.A.3
  • 24
    • 33748469506 scopus 로고    scopus 로고
    • Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis
    • DOI 10.1038/nm1459, PII NM1459
    • M.C. Clarke, N. Figg, J.J. Maguire, A.P. Davenport, M. Goddard, and T.D. Littlewood Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis Nature Medicine 12 2006 1075 1080 (Pubitemid 44353389)
    • (2006) Nature Medicine , vol.12 , Issue.9 , pp. 1075-1080
    • Clarke, M.C.H.1    Figg, N.2    Maguire, J.J.3    Davenport, A.P.4    Goddard, M.5    Littlewood, T.D.6    Bennett, M.R.7
  • 29
    • 15744367559 scopus 로고    scopus 로고
    • Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression
    • DOI 10.1074/jbc.M412862200
    • Y. Liu, S. Sinha, O.G. McDonald, Y. Shang, M.H. Hoofnagle, and G.K. Owens Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression Journal of Biological Chemistry 280 2005 9719 9727 (Pubitemid 40409670)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.10 , pp. 9719-9727
    • Liu, Y.1    Sinha, S.2    McDonald, O.G.3    Shang, Y.4    Hoofnagle, M.H.5    Owens, G.K.6
  • 31
    • 78049294740 scopus 로고    scopus 로고
    • Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1
    • L.M. Villeneuve, M. Kato, M.A. Reddy, M. Wang, L. Lanting, and R. Natarajan Enhanced levels of microRNA-125b in vascular smooth muscle cells of diabetic db/db mice lead to increased inflammatory gene expression by targeting the histone methyltransferase Suv39h1 Diabetes 59 2010 2904 2915
    • (2010) Diabetes , vol.59 , pp. 2904-2915
    • Villeneuve, L.M.1    Kato, M.2    Reddy, M.A.3    Wang, M.4    Lanting, L.5    Natarajan, R.6
  • 32
    • 84863157042 scopus 로고    scopus 로고
    • Negative feedback regulation between microRNA let-7g and the oxLDL receptor LOX-1
    • K.C. Chen, I.C. Hsieh, E. Hsi, Y.S. Wang, C.Y. Dai, and W.W. Chou Negative feedback regulation between microRNA let-7g and the oxLDL receptor LOX-1 Journal of Cell Science 124 2011 4115 4124
    • (2011) Journal of Cell Science , vol.124 , pp. 4115-4124
    • Chen, K.C.1    Hsieh, I.C.2    Hsi, E.3    Wang, Y.S.4    Dai, C.Y.5    Chou, W.W.6
  • 33
    • 22744458273 scopus 로고    scopus 로고
    • Overexpression of lectin-like oxidized low-density lipoprotein receptor-1 induces intramyocardial vasculopathy in apolipoprotein E-null mice
    • DOI 10.1161/01.RES.0000174286.73200.d4
    • K. Inoue, Y. Arai, H. Kurihara, T. Kita, and T. Sawamura Overexpression of lectin-like oxidized low-density lipoprotein receptor-1 induces intramyocardial vasculopathy in apolipoprotein E-null mice Circulation Research 97 2005 176 184 (Pubitemid 41033474)
    • (2005) Circulation Research , vol.97 , Issue.2 , pp. 176-184
    • Inoue, K.1    Arai, Y.2    Kurihara, H.3    Kita, T.4    Sawamura, T.5
  • 36
    • 84869887386 scopus 로고    scopus 로고
    • Simvastatin inhibits the additive activation of ERK1/2 and proliferation of rat vascular smooth muscle cells induced by combined mechanical stress and oxLDL through LOX-1 pathway
    • Z. Zhang, M. Zhang, Y. Li, S. Liu, S. Ping, and J. Wang Simvastatin inhibits the additive activation of ERK1/2 and proliferation of rat vascular smooth muscle cells induced by combined mechanical stress and oxLDL through LOX-1 pathway Cellular Signalling 25 2013 332 340
    • (2013) Cellular Signalling , vol.25 , pp. 332-340
    • Zhang, Z.1    Zhang, M.2    Li, Y.3    Liu, S.4    Ping, S.5    Wang, J.6
  • 37
    • 0032555180 scopus 로고    scopus 로고
    • Neointimal tissue response at sites of coronary stenting in humans: Macroscopic, histological, and immunohistochemical analyses
    • R. Komatsu, M. Ueda, T. Naruko, A. Kojima, and A.E. Becker Neointimal tissue response at sites of coronary stenting in humans: macroscopic, histological, and immunohistochemical analyses Circulation 98 1998 224 233 (Pubitemid 28337613)
    • (1998) Circulation , vol.98 , Issue.3 , pp. 224-233
    • Komatsu, R.1    Ueda, M.2    Naruko, T.3    Kojima, A.4    Becker, A.E.5
  • 38
    • 70350125148 scopus 로고    scopus 로고
    • Final 5-year results of the TAXUS II trial: A randomized study to assess the effectiveness of slow- and moderate-release polymer-based paclitaxel-eluting stents for de novo coronary artery lesions
    • S. Silber, A. Colombo, A.P. Banning, K. Hauptmann, J. Drzewiecki, and E. Grube Final 5-year results of the TAXUS II trial: a randomized study to assess the effectiveness of slow- and moderate-release polymer-based paclitaxel-eluting stents for de novo coronary artery lesions Circulation 120 2009 1498 1504
    • (2009) Circulation , vol.120 , pp. 1498-1504
    • Silber, S.1    Colombo, A.2    Banning, A.P.3    Hauptmann, K.4    Drzewiecki, J.5    Grube, E.6
  • 39
    • 68049083397 scopus 로고    scopus 로고
    • MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation
    • Y. Cheng, X. Liu, J. Yang, Y. Lin, D.Z. Xu, and Q. Lu MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation Circulation Research 105 2009 158 166
    • (2009) Circulation Research , vol.105 , pp. 158-166
    • Cheng, Y.1    Liu, X.2    Yang, J.3    Lin, Y.4    Xu, D.Z.5    Lu, Q.6
  • 40
    • 34250172419 scopus 로고    scopus 로고
    • MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation
    • DOI 10.1161/CIRCRESAHA.106.141986
    • R. Ji, Y. Cheng, J. Yue, J. Yang, X. Liu, and H. Chen MicroRNA expression signature and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation Circulation Research 100 2007 1579 1588 (Pubitemid 46897261)
    • (2007) Circulation Research , vol.100 , Issue.11 , pp. 1579-1588
    • Ji, R.1    Cheng, Y.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6    Dean, D.B.7    Zhang, C.8
  • 41
    • 61949252089 scopus 로고    scopus 로고
    • A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia
    • X. Liu, Y. Cheng, S. Zhang, Y. Lin, J. Yang, and C. Zhang A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia Circulation Research 104 2009 476 487
    • (2009) Circulation Research , vol.104 , pp. 476-487
    • Liu, X.1    Cheng, Y.2    Zhang, S.3    Lin, Y.4    Yang, J.5    Zhang, C.6
  • 42
    • 63649147782 scopus 로고    scopus 로고
    • Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype
    • B.N. Davis, A.C. Hilyard, P.H. Nguyen, G. Lagna, and A. Hata Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype Journal of Biological Chemistry 284 2009 3728 3738
    • (2009) Journal of Biological Chemistry , vol.284 , pp. 3728-3738
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3    Lagna, G.4    Hata, A.5
  • 43
    • 78650897480 scopus 로고    scopus 로고
    • MiR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation
    • S.G. Sun, B. Zheng, M. Han, X.M. Fang, H.X. Li, and S.B. Miao miR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation EMBO Reports 12 2011 56 62
    • (2011) EMBO Reports , vol.12 , pp. 56-62
    • Sun, S.G.1    Zheng, B.2    Han, M.3    Fang, X.M.4    Li, H.X.5    Miao, S.B.6
  • 44
    • 84865253634 scopus 로고    scopus 로고
    • MicroRNA-195 regulates vascular smooth muscle cell phenotype and prevents neointimal formation
    • Y.S. Wang, H.Y. Wang, Y.C. Liao, P.C. Tsai, K.C. Chen, and H.Y. Cheng MicroRNA-195 regulates vascular smooth muscle cell phenotype and prevents neointimal formation Cardiovascular Research 95 2012 517 526
    • (2012) Cardiovascular Research , vol.95 , pp. 517-526
    • Wang, Y.S.1    Wang, H.Y.2    Liao, Y.C.3    Tsai, P.C.4    Chen, K.C.5    Cheng, H.Y.6
  • 46
    • 48249113711 scopus 로고    scopus 로고
    • Conditional deletion of Kruppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury
    • T. Yoshida, K.H. Kaestner, and G.K. Owens Conditional deletion of Kruppel-like factor 4 delays downregulation of smooth muscle cell differentiation markers but accelerates neointimal formation following vascular injury Circulation Research 102 2008 1548 1557
    • (2008) Circulation Research , vol.102 , pp. 1548-1557
    • Yoshida, T.1    Kaestner, K.H.2    Owens, G.K.3
  • 48
    • 80053574272 scopus 로고    scopus 로고
    • MicroRNA-133 controls vascular smooth muscle cell phenotypic switch in vitro and vascular remodeling in vivo
    • D. Torella, C. Iaconetti, D. Catalucci, G.M. Ellison, A. Leone, and C.D. Waring MicroRNA-133 controls vascular smooth muscle cell phenotypic switch in vitro and vascular remodeling in vivo Circulation Research 109 2011 880 893
    • (2011) Circulation Research , vol.109 , pp. 880-893
    • Torella, D.1    Iaconetti, C.2    Catalucci, D.3    Ellison, G.M.4    Leone, A.5    Waring, C.D.6
  • 49
    • 18144368061 scopus 로고    scopus 로고
    • Abdominal aortic aneurysm
    • DOI 10.1016/S0140-6736(05)66459-8
    • N. Sakalihasan, R. Limet, and O.D. Defawe Abdominal aortic aneurysm Lancet 365 2005 1577 1589 (Pubitemid 40615407)
    • (2005) Lancet , vol.365 , Issue.9470 , pp. 1577-1589
    • Sakalihasan, N.1    Limet, R.2    Defawe, O.D.3
  • 51
    • 0034653158 scopus 로고    scopus 로고
    • Risk factors for abdominal aortic aneurysm: Results of a case-control study
    • J.F. Blanchard, H.K. Armenian, and P.P. Friesen Risk factors for abdominal aortic aneurysm: results of a case-control study American Journal of Epidemiology 151 2000 575 583 (Pubitemid 30463602)
    • (2000) American Journal of Epidemiology , vol.151 , Issue.6 , pp. 575-583
    • Blanchard, J.F.1    Armenian, H.K.2    Friesen, P.P.3
  • 52
    • 3042816940 scopus 로고    scopus 로고
    • Abdominal aortic aneurysm expansion: Risk factors and time intervals for surveillance
    • DOI 10.1161/01.CIR.0000133279.07468.9F
    • A.R. Brady, S.G. Thompson, F.G. Fowkes, R.M. Greenhalgh, and J.T. Powell Abdominal aortic aneurysm expansion: risk factors and time intervals for surveillance Circulation 110 2004 16 21 (Pubitemid 38880128)
    • (2004) Circulation , vol.110 , Issue.1 , pp. 16-21
    • Brady, A.R.1    Thompson, S.G.2    Fowkes, F.G.R.3    Greenhalgh, R.M.4    Powell, J.T.5
  • 53
    • 48049115070 scopus 로고    scopus 로고
    • Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte-matrix interactions
    • J. Golledge, M. Karan, C.S. Moran, J. Muller, P. Clancy, and A.E. Dear Reduced expansion rate of abdominal aortic aneurysms in patients with diabetes may be related to aberrant monocyte-matrix interactions European Heart Journal 29 2008 665 672
    • (2008) European Heart Journal , vol.29 , pp. 665-672
    • Golledge, J.1    Karan, M.2    Moran, C.S.3    Muller, J.4    Clancy, P.5    Dear, A.E.6
  • 65
    • 0033817459 scopus 로고    scopus 로고
    • Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension
    • K.B. Lane, R.D. Machado, M.W. Pauciulo, J.R. Thomson, J.A. Phillips 3rd, and J.E. Loyd Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension Nature Genetics 26 2000 81 84
    • (2000) Nature Genetics , vol.26 , pp. 81-84
    • Lane, K.B.1    MacHado, R.D.2    Pauciulo, M.W.3    Thomson, J.R.4    Phillips III, J.A.5    Loyd, J.E.6
  • 70
    • 84862777565 scopus 로고    scopus 로고
    • MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: Results of a network bioinformatics approach
    • V.N. Parikh, R.C. Jin, S. Rabello, N. Gulbahce, K. White, and A. Hale MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach Circulation 125 2012 1520 1532
    • (2012) Circulation , vol.125 , pp. 1520-1532
    • Parikh, V.N.1    Jin, R.C.2    Rabello, S.3    Gulbahce, N.4    White, K.5    Hale, A.6
  • 72
    • 84861589157 scopus 로고    scopus 로고
    • Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia
    • B. Wojciak-Stothard, L. Zhao, E. Oliver, O. Dubois, Y. Wu, and D. Kardassis Role of RhoB in the regulation of pulmonary endothelial and smooth muscle cell responses to hypoxia Circulation Research 110 2012 1423 1434
    • (2012) Circulation Research , vol.110 , pp. 1423-1434
    • Wojciak-Stothard, B.1    Zhao, L.2    Oliver, E.3    Dubois, O.4    Wu, Y.5    Kardassis, D.6
  • 74
    • 66949118228 scopus 로고    scopus 로고
    • Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway
    • M. Brock, M. Trenkmann, R.E. Gay, B.A. Michel, S. Gay, and M. Fischler Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway Circulation Research 104 2009 1184 1191
    • (2009) Circulation Research , vol.104 , pp. 1184-1191
    • Brock, M.1    Trenkmann, M.2    Gay, R.E.3    Michel, B.A.4    Gay, S.5    Fischler, M.6
  • 75
    • 84870511977 scopus 로고    scopus 로고
    • AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension
    • Epub ahead of print
    • M. Brock, V.J. Samillan, M. Trenkmann, C. Schwarzwald, S. Ulrich, and R.E. Gay AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension European Heart Journal 2012 Epub ahead of print
    • (2012) European Heart Journal
    • Brock, M.1    Samillan, V.J.2    Trenkmann, M.3    Schwarzwald, C.4    Ulrich, S.5    Gay, R.E.6
  • 76
    • 67649998366 scopus 로고    scopus 로고
    • MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice
    • A. Bonauer, G. Carmona, M. Iwasaki, M. Mione, M. Koyanagi, and A. Fischer MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice Science 324 2009 1710 1713
    • (2009) Science , vol.324 , pp. 1710-1713
    • Bonauer, A.1    Carmona, G.2    Iwasaki, M.3    Mione, M.4    Koyanagi, M.5    Fischer, A.6
  • 77
    • 77954697250 scopus 로고    scopus 로고
    • Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells
    • C. Doebele, A. Bonauer, A. Fischer, A. Scholz, Y. Reiss, and C. Urbich Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells Blood 115 2010 4944 4950
    • (2010) Blood , vol.115 , pp. 4944-4950
    • Doebele, C.1    Bonauer, A.2    Fischer, A.3    Scholz, A.4    Reiss, Y.5    Urbich, C.6
  • 78
    • 79951819303 scopus 로고    scopus 로고
    • Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension
    • O.D. Liang, S.A. Mitsialis, M.S. Chang, E. Vergadi, C. Lee, and M. Aslam Mesenchymal stromal cells expressing heme oxygenase-1 reverse pulmonary hypertension Stem Cells 29 2011 99 107
    • (2011) Stem Cells , vol.29 , pp. 99-107
    • Liang, O.D.1    Mitsialis, S.A.2    Chang, M.S.3    Vergadi, E.4    Lee, C.5    Aslam, M.6
  • 80
    • 84870239895 scopus 로고    scopus 로고
    • Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension
    • C. Lee, S.A. Mitsialis, M. Aslam, S.H. Vitali, E. Vergadi, and G. Konstantinou Exosomes mediate the cytoprotective action of mesenchymal stromal cells on hypoxia-induced pulmonary hypertension Circulation 126 2012 2601 2611
    • (2012) Circulation , vol.126 , pp. 2601-2611
    • Lee, C.1    Mitsialis, S.A.2    Aslam, M.3    Vitali, S.H.4    Vergadi, E.5    Konstantinou, G.6
  • 81
    • 84864229176 scopus 로고    scopus 로고
    • A role for miR-145 in pulmonary arterial hypertension: Evidence from mouse models and patient samples
    • P. Caruso, Y. Dempsie, H.C. Stevens, R.A. McDonald, L. Long, and R. Lu A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples Circulation Research 111 2012 290 300
    • (2012) Circulation Research , vol.111 , pp. 290-300
    • Caruso, P.1    Dempsie, Y.2    Stevens, H.C.3    McDonald, R.A.4    Long, L.5    Lu, R.6
  • 82
    • 80051532504 scopus 로고    scopus 로고
    • Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4
    • B.N. Davis-Dusenbery, M.C. Chan, K.E. Reno, A.S. Weisman, M.D. Layne, and G. Lagna Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4 Journal of Biological Chemistry 286 2011 28097 28110
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 28097-28110
    • Davis-Dusenbery, B.N.1    Chan, M.C.2    Reno, K.E.3    Weisman, A.S.4    Layne, M.D.5    Lagna, G.6
  • 83
    • 80051944105 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 (TGF-beta1) utilizes distinct pathways for the transcriptional activation of microRNA 143/145 in human coronary artery smooth muscle cells
    • X. Longand, and J.M. Miano Transforming growth factor-beta1 (TGF-beta1) utilizes distinct pathways for the transcriptional activation of microRNA 143/145 in human coronary artery smooth muscle cells Journal of Biological Chemistry 286 2011 30119 30129
    • (2011) Journal of Biological Chemistry , vol.286 , pp. 30119-30129
    • Longand, X.1    Miano, J.M.2
  • 87
    • 84863419659 scopus 로고    scopus 로고
    • The microRNA-328 regulates hypoxic pulmonary hypertension by targeting at insulin growth factor 1 receptor and L-type calcium channel-alpha1C
    • L. Guo, Z. Qiu, L. Wei, X. Yu, X. Gao, and S. Jiang The microRNA-328 regulates hypoxic pulmonary hypertension by targeting at insulin growth factor 1 receptor and L-type calcium channel-alpha1C Hypertension 59 2012 1006 1013
    • (2012) Hypertension , vol.59 , pp. 1006-1013
    • Guo, L.1    Qiu, Z.2    Wei, L.3    Yu, X.4    Gao, X.5    Jiang, S.6
  • 88
    • 43049097195 scopus 로고    scopus 로고
    • Global burden of blood-pressure-related disease, 2001
    • DOI 10.1016/S0140-6736(08)60655-8, PII S0140673608606558
    • C.M. Lawes, S. Vander Hoorn, and A. Rodgers Global burden of blood-pressure-related disease, 2001 Lancet 371 2008 1513 1518 (Pubitemid 351626187)
    • (2008) The Lancet , vol.371 , Issue.9623 , pp. 1513-1518
    • Lawes, C.M.1    Hoorn, S.V.2    Rodgers, A.3
  • 90
    • 84857636799 scopus 로고    scopus 로고
    • MicroRNAs in hypertension: Mechanisms and therapeutic targets
    • S. Batkaiand, and T. Thum MicroRNAs in hypertension: mechanisms and therapeutic targets Current Hypertension Reports 14 2012 79 87
    • (2012) Current Hypertension Reports , vol.14 , pp. 79-87
    • Batkaiand, S.1    Thum, T.2
  • 91
    • 84868475728 scopus 로고    scopus 로고
    • MicroRNA therapeutics for cardiovascular disease: Opportunities and obstacles
    • E. van Rooijand, and E.N. Olson MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles Nature Reviews Drug Discovery 11 2012 860 872
    • (2012) Nature Reviews Drug Discovery , vol.11 , pp. 860-872
    • Van Rooijand, E.1    Olson, E.N.2
  • 92
    • 79952338927 scopus 로고    scopus 로고
    • Vascular smooth muscle cell proliferation is influenced by let-7d microRNA and its interaction with KRAS
    • M.L. Yu, J.F. Wang, G.K. Wang, X.H. You, X.X. Zhao, and Q. Jing Vascular smooth muscle cell proliferation is influenced by let-7d microRNA and its interaction with KRAS Circulation Journal 75 2011 703 709
    • (2011) Circulation Journal , vol.75 , pp. 703-709
    • Yu, M.L.1    Wang, J.F.2    Wang, G.K.3    You, X.H.4    Zhao, X.X.5    Jing, Q.6
  • 93
    • 84878214305 scopus 로고    scopus 로고
    • Myocardin and microRNA-1 modulate bladder activity through connexin 43 expression during post-natal development
    • Epub ahead of print
    • M. Imamura, Y. Sugino, X. Long, O.J. Slivano, N. Nishikawa, and N. Yoshimura Myocardin and microRNA-1 modulate bladder activity through connexin 43 expression during post-natal development Journal of Cellular Physiology 2013 Epub ahead of print
    • (2013) Journal of Cellular Physiology
    • Imamura, M.1    Sugino, Y.2    Long, X.3    Slivano, O.J.4    Nishikawa, N.5    Yoshimura, N.6
  • 94
    • 78951495879 scopus 로고    scopus 로고
    • MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4
    • C. Xie, H. Huang, X. Sun, Y. Guo, M. Hamblin, and R.P. Ritchie MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4 Stem Cells and Development 20 2011 205 210
    • (2011) Stem Cells and Development , vol.20 , pp. 205-210
    • Xie, C.1    Huang, H.2    Sun, X.3    Guo, Y.4    Hamblin, M.5    Ritchie, R.P.6
  • 95
    • 84870494129 scopus 로고    scopus 로고
    • Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice
    • T. Minami, K. Kuwahara, Y. Nakagawa, M. Takaoka, H. Kinoshita, and K. Nakao Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice EMBO Journal 31 2012 4428 4440
    • (2012) EMBO Journal , vol.31 , pp. 4428-4440
    • Minami, T.1    Kuwahara, K.2    Nakagawa, Y.3    Takaoka, M.4    Kinoshita, H.5    Nakao, K.6
  • 96
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • DOI 10.1038/nature07086, PII NATURE07086
    • B.N. Davis, A.C. Hilyard, G. Lagna, and A. Hata SMAD proteins control DROSHA-mediated microRNA maturation Nature 454 2008 56 61 (Pubitemid 351931982)
    • (2008) Nature , vol.454 , Issue.7200 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 98
    • 80053182836 scopus 로고    scopus 로고
    • Implication of microRNAs in atrial natriuretic peptide and nitric oxide signaling in vascular smooth muscle cells
    • K.U. Kotlo, B. Hesabi, and R.S. Danziger Implication of microRNAs in atrial natriuretic peptide and nitric oxide signaling in vascular smooth muscle cells American Journal of Physiology: Cell Physiology 301 2011 C929 C937
    • (2011) American Journal of Physiology: Cell Physiology , vol.301
    • Kotlo, K.U.1    Hesabi, B.2    Danziger, R.S.3
  • 99
    • 80052148252 scopus 로고    scopus 로고
    • MicroRNA-21 regulates vascular smooth muscle cell function via targeting tropomyosin 1 in arteriosclerosis obliterans of lower extremities
    • M. Wang, W. Li, G.Q. Chang, C.S. Ye, J.S. Ou, and X.X. Li MicroRNA-21 regulates vascular smooth muscle cell function via targeting tropomyosin 1 in arteriosclerosis obliterans of lower extremities Arteriosclerosis, Thrombosis, and Vascular Biology 31 2011 2044 2053
    • (2011) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.31 , pp. 2044-2053
    • Wang, M.1    Li, W.2    Chang, G.Q.3    Ye, C.S.4    Ou, J.S.5    Li, X.X.6
  • 100
    • 84862094335 scopus 로고    scopus 로고
    • MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells
    • G. Yang, Y. Pei, Q. Cao, and R. Wang MicroRNA-21 represses human cystathionine gamma-lyase expression by targeting at specificity protein-1 in smooth muscle cells Journal of Cellular Physiology 227 2012 3192 3200
    • (2012) Journal of Cellular Physiology , vol.227 , pp. 3192-3200
    • Yang, G.1    Pei, Y.2    Cao, Q.3    Wang, R.4
  • 101
    • 84856718814 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins
    • H. Kang, B.N. Davis-Dusenbery, P.H. Nguyen, A. Lal, J. Lieberman, and L. Van Aelst Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins Journal of Biological Chemistry 287 2012 3976 3986
    • (2012) Journal of Biological Chemistry , vol.287 , pp. 3976-3986
    • Kang, H.1    Davis-Dusenbery, B.N.2    Nguyen, P.H.3    Lal, A.4    Lieberman, J.5    Van Aelst, L.6
  • 102
    • 76349093390 scopus 로고    scopus 로고
    • Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression
    • M.C. Chan, A.C. Hilyard, C. Wu, B.N. Davis, N.S. Hill, and A. Lal Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression EMBO Journal 29 2010 559 573
    • (2010) EMBO Journal , vol.29 , pp. 559-573
    • Chan, M.C.1    Hilyard, A.C.2    Wu, C.3    Davis, B.N.4    Hill, N.S.5    Lal, A.6
  • 103
    • 77956539987 scopus 로고    scopus 로고
    • Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3beta
    • J.S. Mohamed, M.A. Lopez, and A.M. Boriek Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3beta Journal of Biological Chemistry 285 2010 29336 29347
    • (2010) Journal of Biological Chemistry , vol.285 , pp. 29336-29347
    • Mohamed, J.S.1    Lopez, M.A.2    Boriek, A.M.3
  • 106
    • 84871872493 scopus 로고    scopus 로고
    • Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification
    • Y. Du, C. Gao, Z. Liu, L. Wang, B. Liu, and F. He Upregulation of a disintegrin and metalloproteinase with thrombospondin motifs-7 by miR-29 repression mediates vascular smooth muscle calcification Arteriosclerosis, Thrombosis, and Vascular Biology 32 2012 2580 2588
    • (2012) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.32 , pp. 2580-2588
    • Du, Y.1    Gao, C.2    Liu, Z.3    Wang, L.4    Liu, B.5    He, F.6
  • 107
    • 79955654219 scopus 로고    scopus 로고
    • OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: A novel mechanism for cardiovascular diseases
    • K.C. Chen, Y.S. Wang, C.Y. Hu, W.C. Chang, Y.C. Liao, and C.Y. Dai OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases FASEB Journal 25 2011 1718 1728
    • (2011) FASEB Journal , vol.25 , pp. 1718-1728
    • Chen, K.C.1    Wang, Y.S.2    Hu, C.Y.3    Chang, W.C.4    Liao, Y.C.5    Dai, C.Y.6
  • 110
    • 77954890718 scopus 로고    scopus 로고
    • Repression of versican expression by microRNA-143
    • X. Wang, G. Hu, and J. Zhou Repression of versican expression by microRNA-143 Journal of Biological Chemistry 285 2010 23241 23250
    • (2010) Journal of Biological Chemistry , vol.285 , pp. 23241-23250
    • Wang, X.1    Hu, G.2    Zhou, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.