MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling

Nature Cell Biology

Volumn 12, Issue 12, 2010, Pages 1220-1227

  Da Costa Martins, Paula A ^a,b   Salic, Kanita ^a,b   Gladka, Monika M ^a   Armand, Anne Sophie ^c   Leptidis, Stefanos ^a,b   El Azzouzi, Hamid ^a,b   Hansen, Arne ^d   Coenen De Roo, Christina J ^e   Bierhuizen, Marti F ^f   Van Der Nagel, Roel ^f   Van Kuik, Joyce ^g   De Weger, Roel ^g   De Bruin, Alain ^h   Condorelli, Gianluigi ⁱ   Arbones, Maria L ^j   Eschenhagen, Thomas ^d   De Windt, Leon J ^b  

^a HUBRECHT INSTITUTE   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c CNRS   (France)

^d UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^e Harlan   (Switzerland)

^f Departments of Medical Physiology   (Netherlands)

^g UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^h UTRECHT UNIVERSITY   (Netherlands)

ⁱ CNR   (Italy)

^j CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES RARAS CIBERER   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; DUAL SPECIFICITY TYROSINE PHOSPHORYLATION REGULATED KINASE 1A; MICRORNA; MICRORNA 199B; PHOSPHOTRANSFERASE; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMEGALY; CELL STRAIN HEK293; CONTROLLED STUDY; GENE AMPLIFICATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE TARGETING; HEART FAILURE; HEART HYPERTROPHY; HEART MUSCLE FIBROSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MOUSE; MOUSE MUTANT; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; CALCINEURIN; HEART FAILURE; HUMANS; MICE; MICE, TRANSGENIC; MICRORNAS; NFATC TRANSCRIPTION FACTORS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RATS; SIGNAL TRANSDUCTION;

MUS;

EID: 78649843756     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb2126     Document Type: Article

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