MicroRNA regulation of cardiac conduction and arrhythmias

Translational Research

Volumn 161, Issue 5, 2013, Pages 381-392

  Kim, Gene H ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGOMIR; ANTISENSE OLIGONUCLEOTIDE; CALCIUM ION; ION CHANNEL; MICRORNA;

ABLATION THERAPY; ARRHYTHMOGENESIS; ARTICLE; ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; DEPOLARIZATION; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART AUTOMATICITY; HEART CONDUCTION; HEART DEATH; HEART FAILURE; HEART INFARCTION; HEART MUSCLE EXCITABILITY; HEART RHYTHM; HUMAN; MEDICAL DEVICE; MORBIDITY; MORTALITY; NONHUMAN; PRIORITY JOURNAL; SUDDEN DEATH; TISSUE REGENERATION;

EID: 84876359742     PISSN: 19315244     EISSN: 18781810     Source Type: Journal    
DOI: 10.1016/j.trsl.2012.12.004     Document Type: Review

References (80)

1. E. Marban Cardiac channelopathies Nature 415 2002 213 218
2. V. Fuster, L.E. Ryden, and D.S. Cannom ACC/AHA/ESC 2006 Guidelines for the Management of Patients with Atrial Fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation): developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society Circulation 114 2006 e257 e354
3. M.J. Janse Electrophysiological changes in heart failure and their relationship to arrhythmogenesis Cardiovasc Res 61 2004 208 217
4. C.A. Martin, G.D. Matthews, and C.L. Huang Sudden cardiac death and inherited channelopathy: the basic electrophysiology of the myocyte and myocardium in ion channel disease Heart 98 2012 536 543
5. Y. Lee, C. Ahn, and J. Han The nuclear RNase III Drosha initiates microRNA processing Nature 425 2003 415 419
6. X. Liu, D.Y. Jin, M.T. McManus, and Z. Mourelatos Precursor microRNA-programmed silencing complex assembly pathways in mammals Mol Cell 46 2012 507 517
7. V.N. Kim, J. Han, and M.C. Siomi Biogenesis of small RNAs in animals Nat Rev Mol Cell Biol 10 2009 126 139
8. D.P. Bartel MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
9. V. Ambros The functions of animal microRNAs Nature 431 2004 350 355
10. M. Lagos-Quintana, R. Rauhut, W. Lendeckel, and T. Tuschl Identification of novel genes coding for small expressed RNAs Science 294 2001 853 858
11. J. Schlesinger, M. Schueler, and M. Grunert The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs PLoS Genet 7 2011 e1001313
12. C.Y. Chen, S.T. Chen, C.S. Fuh, H.F. Juan, and H.C. Huang Coregulation of transcription factors and microRNAs in human transcriptional regulatory network BMC Bioinformatics 12 Suppl 1 2011 S41
13. J. Bauersachs, and T. Thum Biogenesis and regulation of cardiovascular microRNAs Circ Res 109 2011 334 337
14. T. Boettger, and T. Braun A new level of complexity: the role of microRNAs in cardiovascular development Circ Res 110 2012 1000 1003
15. G.W. Dorn II MicroRNAs in cardiac disease Transl Res 157 2011 226 235
16. J. Elmen, M. Lindow, and S. Schutz LNA-mediated microRNA silencing in non-human primates Nature 452 2008 896 899
17. R.E. Lanford, E.S. Hildebrandt-Eriksen, and A. Petri Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection Science 327 2010 198 201
18. J. Krutzfeldt, N. Rajewsky, and R. Braich Silencing of microRNAs in vivo with 'antagomirs' Nature 438 2005 685 689
19. E. van Rooij, and E.N. Olson MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles Nat Rev Drug Discov 11 2012 860 872
20. M.S. Ebert, J.R. Neilson, and P.A. Sharp MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells Nat Methods 4 2007 721 726
21. A. Care, D. Catalucci, and F. Felicetti MicroRNA-133 controls cardiac hypertrophy Nat Med 13 2007 613 618
22. A.S. Amin, H.L. Tan, and A.A. Wilde Cardiac ion channels in health and disease Heart Rhythm 7 2010 117 126
23. J.M. Nerbonne, and R.S. Kass Molecular physiology of cardiac repolarization Physiol Rev 85 2005 1205 1253
24. M.E. Mangoni, and J. Nargeot Genesis and regulation of the heart automaticity Physiol Rev 88 2008 919 982
25. W. Shi, R. Wymore, and H. Yu Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues Circ Res 85 1999 e1 e6
26. A.G. Kleber, and Y. Rudy Basic mechanisms of cardiac impulse propagation and associated arrhythmias Physiol Rev 84 2004 431 488
27. O. Campuzano, R. Brugada, and A. Iglesias Genetics of Brugada syndrome Curr Opin Cardiol 25 2010 210 215
28. A. Maguy, S. Le Bouter, and P. Comtois Ion channel subunit expression changes in cardiac Purkinje fibers: a potential role in conduction abnormalities associated with congestive heart failure Circ Res 104 2009 1113 1122
29. I. Bodi, G. Mikala, S.E. Koch, S.A. Akhter, and A. Schwartz The L-type calcium channel in the heart: the beat goes on J Clin Invest 115 2005 3306 3317
30. N. Klugbauer, A. Welling, V. Specht, C. Seisenberger, and F. Hofmann L-type Ca2+ channels of the embryonic mouse heart Eur J Pharmacol 447 2002 279 284
31. C. Christel, N. Cardona, and P. Mesirca Distinct localization and modulation of Cav1.2 and Cav1.3 L-type Ca2+ channels in mouse sinoatrial node J Physiol 590 2012 6327 6341
32. Q. Zhang, V. Timofeyev, and H. Qiu Expression and roles of Cav1.3 (alpha1D) L-type Ca(2)+ channel in atrioventricular node automaticity J Mol Cell Cardiol 50 2011 194 202
33. K. Ono, and T. Iijima Cardiac T-type Ca(2+) channels in the heart J Mol Cell Cardiol 48 2010 65 70
34. S.A. Goonasekera, K. Hammer, and M. Auger-Messier Decreased cardiac L-type Ca(2)(+) channel activity induces hypertrophy and heart failure in mice J Clin Invest 122 2012 280 290
35. I. Splawski, K.W. Timothy, and N. Decher Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations Proc Natl Acad Sci U S A 102 2005 8089 8096 discussion 6-8
36. A. Jacobs, B.P. Knight, K.T. McDonald, and M.C. Burke Verapamil decreases ventricular tachyarrhythmias in a patient with Timothy syndrome (LQT8) Heart Rhythm 3 2006 967 970
37. S. Sicouri, K.W. Timothy, and A.C. Zygmunt Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine Heart Rhythm 4 2007 638 647
38. Y. Lu, Y. Zhang, and N. Wang MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation Circulation 122 2010 2378 2387
39. W.J. Groh, M.R. Groh, and C. Saha Electrocardiographic abnormalities and sudden death in myotonic dystrophy type 1 N Engl J Med 358 2008 2688 2697
40. F. Charpentier, J. Merot, G. Loussouarn, and I. Baro Delayed rectifier K(+) currents and cardiac repolarization J Mol Cell Cardiol 48 2010 37 44
41. J. Silva, and Y. Rudy Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve Circulation 112 2005 1384 1391
42. N. Jost, L. Virag, and M. Bitay Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle Circulation 112 2005 1392 1399
43. D.W. Liu, and C. Antzelevitch Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes. A weaker IKs contributes to the longer action potential of the M cell Circ Res 76 1995 351 365
44. C. Ramakers, M. Stengl, R.L. Spatjens, A.F. Moorman, and M.A. Vos Molecular and electrical characterization of the canine cardiac ventricular septum J Mol Cell Cardiol 38 2005 153 161
45. N. Szentadrassy, T. Banyasz, and T. Biro Apico-basal inhomogeneity in distribution of ion channels in canine and human ventricular myocardium Cardiovasc Res 65 2005 851 860
46. Y. Zhao, J.F. Ransom, and A. Li Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2 Cell 129 2007 303 317
47. D.L. Costantini, E.P. Arruda, and P. Agarwal The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient Cell 123 2005 347 358
48. B. Yang, H. Lin, and J. Xiao The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2 Nat Med 13 2007 486 491
49. Z. Girmatsion, P. Biliczki, and A. Bonauer Changes in microRNA-1 expression and IK1 up-regulation in human atrial fibrillation Heart Rhythm 6 2009 1802 1809
50. M. Lagos-Quintana, R. Rauhut, A. Yalcin, J. Meyer, W. Lendeckel, and T. Tuschl Identification of tissue-specific microRNAs from mouse Curr Biol 12 2002 735 739
51. S.J. Matkovich, W. Wang, and Y. Tu MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts Circ Res 106 2010 166 175
52. K. Ohnishi, H. Yoshida, and K. Shigeno Prolongation of the QT interval and ventricular tachycardia in patients treated with arsenic trioxide for acute promyelocytic leukemia Ann Intern Med 133 2000 881 885
53. J.T. Barbey, J.C. Pezzullo, and S.L. Soignet Effect of arsenic trioxide on QT interval in patients with advanced malignancies J Clin Oncol 21 2003 3609 3615
54. H. Shan, Y. Zhang, and B. Cai Upregulation of microRNA-1 and microRNA-133 contributes to arsenic-induced cardiac electrical remodeling Int J Cardiol 2012
55. T. Thum, P. Galuppo, and C. Wolf MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure Circulation 116 2007 258 267
56. Y. Hou, Y. Sun, and H. Shan Beta-adrenoceptor regulates miRNA expression in rat heart Med Sci Monit 18 2012 BR309 BR314
57. D. Goldoni, J.M. Yarham, and M.K. McGahon A novel dual-fluorescence strategy for functionally validating microRNA targets in 3-prime untranslated regions: regulation of the inward rectifier potassium channel Kir2.1 by miR-212 Biochem J 448 2012 103 113
58. J. Xiao, D. Liang, and Y. Zhang MicroRNA expression signature in atrial fibrillation with mitral stenosis Physiol Genomics 43 2011 655 664
59. H.F. Xu, Y.J. Ding, and Y.W. Shen MicroRNA- 1 represses Cx43 expression in viral myocarditis Mol Cell Biochem 362 2012 141 148
60. D. Terentyev, A.E. Belevych, and R. Terentyeva miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2 Circ Res 104 2009 514 521
61. N.S. Peters, J. Coromilas, N.J. Severs, and A.L. Wit Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia Circulation 95 1997 988 996
62. J.A. Yao, W. Hussain, P. Patel, N.S. Peters, P.A. Boyden, and A.L. Wit Remodeling of gap junctional channel function in epicardial border zone of healing canine infarcts Circ Res 92 2003 437 443
63. S. Nattel, A. Maguy, S. Le Bouter, and Y.H. Yeh Arrhythmogenic ion-channel remodeling in the heart: heart failure, myocardial infarction, and atrial fibrillation Physiol Rev 87 2007 425 456
64. T.E. Callis, K. Pandya, and H.Y. Seok MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice J Clin Invest 119 2009 2772 2786
65. E. van Rooij, L.B. Sutherland, X. Qi, J.A. Richardson, J. Hill, and E.N. Olson Control of stress-dependent cardiac growth and gene expression by a microRNA Science 316 2007 575 579
66. A.M. Simon, D.A. Goodenough, and D.L. Paul Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block Curr Biol 8 1998 295 298
67. C.W. Lo Role of gap junctions in cardiac conduction and development: insights from the connexin knockout mice Circ Res 87 2000 346 348
68. R.L. Montgomery, T.G. Hullinger, and H.M. Semus Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure Circulation 124 2011 1537 1547
69. S.M. Pogwizd, K. Schlotthauer, L. Li, W. Yuan, and D.M. Bers Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness Circ Res 88 2001 1159 1167
70. X. Ai, J.W. Curran, T.R. Shannon, D.M. Bers, and S.M. Pogwizd Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure Circ Res 97 2005 1314 1322
71. S.M. Pogwizd, and D.M. Bers Cellular basis of triggered arrhythmias in heart failure Trends Cardiovasc Med 14 2004 61 66
72. H.A. Fozzard Afterdepolarizations and triggered activity Basic Res Cardiol 87 Suppl 2 1992 105 113
73. J. Fauconnier, A. Lacampagne, J.M. Rauzier, G. Vassort, and S. Richard Ca2+-dependent reduction of IK1 in rat ventricular cells: a novel paradigm for arrhythmia in heart failure? Cardiovasc Res 68 2005 204 212
74. A.E. Belevych, S.E. Sansom, and R. Terentyeva MicroRNA-1 and -133 increase arrhythmogenesis in heart failure by dissociating phosphatase activity from RyR2 complex PLoS One 6 2011 e28324
75. N. Cooley, M.J. Cowley, and R.C. Lin Influence of atrial fibrillation on microRNA expression profiles in left and right atria from patients with valvular heart disease Physiol Genomics 44 2012 211 219
76. O. Adam, B. Lohfelm, and T. Thum Role of miR-21 in the pathogenesis of atrial fibrosis Basic Res Cardiol 107 2012 278
77. A. Goette, U. Lendeckel, and A. Kuchenbecker Cigarette smoking induces atrial fibrosis in humans via nicotine Heart 93 2007 1056 1063
78. M. Yashima, T. Ohara, and J.M. Cao Nicotine increases ventricular vulnerability to fibrillation in hearts with healed myocardial infarction Am J Physiol Heart Circ Physiol 278 2000 H2124 H2133
79. N.L. Benowitz, and S.G. Gourlay Cardiovascular toxicity of nicotine: implications for nicotine replacement therapy J Am Coll Cardiol 29 1997 1422 1431
80. H. Shan, Y. Zhang, and Y. Lu Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines Cardiovasc Res 83 2009 465 472