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Volumn 323, Issue , 2016, Pages 157-169

Crucial role of astrocytes in temporal lobe epilepsy

Author keywords

Adenosine kinase; Antiepileptic drugs; Astrocyte; Connexin; Kir channel; Water channel

Indexed keywords

AQUAPORIN 4; CONNEXIN 30; CONNEXIN 43; GAP JUNCTION PROTEIN; GLIOTRANSMITTER; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; NEUROTRANSMITTER; POTASSIUM CHANNEL; POTASSIUM CHANNEL KIR4.1; UNCLASSIFIED DRUG; ANTICONVULSIVE AGENT;

EID: 84921961947     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.12.047     Document Type: Article
Times cited : (84)

References (181)
  • 2
    • 0031562362 scopus 로고    scopus 로고
    • Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats
    • Akbar M.T., Torp R., Danbolt N.C., Levy L.M., Meldrum B.S., Ottersen O.P. Expression of glial glutamate transporters GLT-1 and GLAST is unchanged in the hippocampus in fully kindled rats. Neuroscience 1997, 78:351-359.
    • (1997) Neuroscience , vol.78 , pp. 351-359
    • Akbar, M.T.1    Torp, R.2    Danbolt, N.C.3    Levy, L.M.4    Meldrum, B.S.5    Ottersen, O.P.6
  • 4
    • 3843109172 scopus 로고    scopus 로고
    • Glutamate released from glial cells synchronizes neuronal activity in the hippocampus
    • Angulo M.C., Kozlov A.S., Charpak S., Audinat E. Glutamate released from glial cells synchronizes neuronal activity in the hippocampus. J Neurosci 2004, 24:6920-6927.
    • (2004) J Neurosci , vol.24 , pp. 6920-6927
    • Angulo, M.C.1    Kozlov, A.S.2    Charpak, S.3    Audinat, E.4
  • 6
    • 0034950760 scopus 로고    scopus 로고
    • Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex
    • Aronica E., Gorter J.A., Jansen G.H., Leenstra S., Yankaya B., Troost D. Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex. Acta Neuropathol (Berl) 2001, 101:449-459.
    • (2001) Acta Neuropathol (Berl) , vol.101 , pp. 449-459
    • Aronica, E.1    Gorter, J.A.2    Jansen, G.H.3    Leenstra, S.4    Yankaya, B.5    Troost, D.6
  • 7
    • 0000926233 scopus 로고    scopus 로고
    • Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy
    • Aronica E., Van Vliet E.A., Mayboroda O.A., Troost D., Da Silva F.H.L., Gorter J.A. Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy. Eur J Neurosci 2000, 12:2333-2344.
    • (2000) Eur J Neurosci , vol.12 , pp. 2333-2344
    • Aronica, E.1    Van Vliet, E.A.2    Mayboroda, O.A.3    Troost, D.4    Da Silva, F.H.L.5    Gorter, J.A.6
  • 10
    • 0022452248 scopus 로고
    • Chlorpromazine protects brain tissue in hypoxia by delaying spreading depression-mediated calcium influx
    • Balestrino M., Somjen G.G. Chlorpromazine protects brain tissue in hypoxia by delaying spreading depression-mediated calcium influx. Brain Res 1986, 385:219-226.
    • (1986) Brain Res , vol.385 , pp. 219-226
    • Balestrino, M.1    Somjen, G.G.2
  • 11
    • 0035369037 scopus 로고    scopus 로고
    • A neuron-glia signalling network in the active brain
    • Bezzi P., Volterra A. A neuron-glia signalling network in the active brain. Curr Opin Neurobiol 2001, 11:387-394.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 387-394
    • Bezzi, P.1    Volterra, A.2
  • 13
    • 58149280525 scopus 로고    scopus 로고
    • Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period
    • Biagini G., Longo D., Baldelli E., Zoli M., Rogawski M.A., Bertazzoni G., Avoli M. Neurosteroids and epileptogenesis in the pilocarpine model: evidence for a relationship between P450scc induction and length of the latent period. Epilepsia 2009, 50(Suppl. 1):53-58.
    • (2009) Epilepsia , vol.50 , pp. 53-58
    • Biagini, G.1    Longo, D.2    Baldelli, E.3    Zoli, M.4    Rogawski, M.A.5    Bertazzoni, G.6    Avoli, M.7
  • 15
    • 1542290152 scopus 로고    scopus 로고
    • Increased seizure threshold in mice lacking aquaporin-4 water channels
    • Binder D.K., Oshio K., Ma T., Verkman A.S., Manley G.T. Increased seizure threshold in mice lacking aquaporin-4 water channels. NeuroReport 2004, 15:259-262.
    • (2004) NeuroReport , vol.15 , pp. 259-262
    • Binder, D.K.1    Oshio, K.2    Ma, T.3    Verkman, A.S.4    Manley, G.T.5
  • 16
    • 4644268435 scopus 로고    scopus 로고
    • In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching
    • Binder D.K., Papadopoulos M.C., Haggie P.M., Verkman A.S. In vivo measurement of brain extracellular space diffusion by cortical surface photobleaching. J Neurosci 2004, 24:8049-8056.
    • (2004) J Neurosci , vol.24 , pp. 8049-8056
    • Binder, D.K.1    Papadopoulos, M.C.2    Haggie, P.M.3    Verkman, A.S.4
  • 17
    • 33748857971 scopus 로고    scopus 로고
    • Functional changes in astroglial cells in epilepsy
    • Binder D.K., Steinhäuser C. Functional changes in astroglial cells in epilepsy. Glia 2006, 54:358-368.
    • (2006) Glia , vol.54 , pp. 358-368
    • Binder, D.K.1    Steinhäuser, C.2
  • 19
    • 13544274000 scopus 로고    scopus 로고
    • Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies
    • Boison D. Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies. Neuroscientist 2005, 11:25-36.
    • (2005) Neuroscientist , vol.11 , pp. 25-36
    • Boison, D.1
  • 20
    • 84862317564 scopus 로고    scopus 로고
    • Adenosine dysfunction in epilepsy
    • Boison D. Adenosine dysfunction in epilepsy. Glia 2012, 60:1234-1243.
    • (2012) Glia , vol.60 , pp. 1234-1243
    • Boison, D.1
  • 21
    • 0032169291 scopus 로고    scopus 로고
    • Properties of human glial cells associated with epileptic seizure foci
    • Bordey A., Sontheimer H. Properties of human glial cells associated with epileptic seizure foci. Epilepsy Res 1998, 32:286-303.
    • (1998) Epilepsy Res , vol.32 , pp. 286-303
    • Bordey, A.1    Sontheimer, H.2
  • 22
    • 33748759806 scopus 로고    scopus 로고
    • The effects of octanol on penicillin induced epileptiform activity in rats: an in vivo study
    • Bostanci M.O., Bagirici F. The effects of octanol on penicillin induced epileptiform activity in rats: an in vivo study. Epilepsy Res 2006, 71:188-194.
    • (2006) Epilepsy Res , vol.71 , pp. 188-194
    • Bostanci, M.O.1    Bagirici, F.2
  • 23
    • 33846330866 scopus 로고    scopus 로고
    • Anticonvulsive effects of carbenoxolone on penicillin-induced epileptiform activity: an in vivo study
    • Bostanci M.O., Bagirici F. Anticonvulsive effects of carbenoxolone on penicillin-induced epileptiform activity: an in vivo study. Neuropharmcology 2007, 52:362-367.
    • (2007) Neuropharmcology , vol.52 , pp. 362-367
    • Bostanci, M.O.1    Bagirici, F.2
  • 25
    • 84873713858 scopus 로고    scopus 로고
    • Fast spiking interneuron control of seizure propagation in a cortical slice model of focal epilepsy
    • Cammarota M., Losi G., Chiavegato A., Zonta M., Carmignoto G. Fast spiking interneuron control of seizure propagation in a cortical slice model of focal epilepsy. J Physiol 2013, 591:807-822.
    • (2013) J Physiol , vol.591 , pp. 807-822
    • Cammarota, M.1    Losi, G.2    Chiavegato, A.3    Zonta, M.4    Carmignoto, G.5
  • 26
    • 84869499315 scopus 로고    scopus 로고
    • Curious and contradictory roles of glial connexins and pannexins in epilepsy
    • Carlen P.L. Curious and contradictory roles of glial connexins and pannexins in epilepsy. Brain Res 2012, 1487:54-60.
    • (2012) Brain Res , vol.1487 , pp. 54-60
    • Carlen, P.L.1
  • 28
    • 0028879447 scopus 로고
    • Hypotonic exposure enhances synaptic transmission and triggers spreading depression in rat hippocampal tissue slices
    • Chebabo S.R., Hester M.A., Aitken P.G., Somjen G.G. Hypotonic exposure enhances synaptic transmission and triggers spreading depression in rat hippocampal tissue slices. Brain Res 1995, 695:203-216.
    • (1995) Brain Res , vol.695 , pp. 203-216
    • Chebabo, S.R.1    Hester, M.A.2    Aitken, P.G.3    Somjen, G.G.4
  • 29
    • 78649418068 scopus 로고    scopus 로고
    • Implication of kir4.1 channel in excess potassium clearance: an in vivo study on anesthetized glial-conditional kir4.1 knock-out mice
    • Chever O., Djukic B., McCarthy K.D., Amzica F. Implication of kir4.1 channel in excess potassium clearance: an in vivo study on anesthetized glial-conditional kir4.1 knock-out mice. J Neurosci 2010, 30:15769-15777.
    • (2010) J Neurosci , vol.30 , pp. 15769-15777
    • Chever, O.1    Djukic, B.2    McCarthy, K.D.3    Amzica, F.4
  • 30
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988, 1:623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 31
    • 84886434371 scopus 로고    scopus 로고
    • Astrocyte control of synaptic NMDA receptors contributes to the progressive development of temporal lobe epilepsy
    • Clasadonte J., Dong J., Hines D.J., Haydon P.G. Astrocyte control of synaptic NMDA receptors contributes to the progressive development of temporal lobe epilepsy. Proc Natl Acad Sci U S A 2013, 110:17540-17545.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 17540-17545
    • Clasadonte, J.1    Dong, J.2    Hines, D.J.3    Haydon, P.G.4
  • 33
    • 0036395041 scopus 로고    scopus 로고
    • Connexin-30 mRNA is up-regulated in astrocytes and expressed in apoptotic neuronal cells of rat brain following kainate-induced seizures
    • Condorelli D.F., Mudo G., Trovato-Salinaro A., Mirone M.B., Amato G., Belluardo N. Connexin-30 mRNA is up-regulated in astrocytes and expressed in apoptotic neuronal cells of rat brain following kainate-induced seizures. Mol Cell Neurosci 2002, 21:94-113.
    • (2002) Mol Cell Neurosci , vol.21 , pp. 94-113
    • Condorelli, D.F.1    Mudo, G.2    Trovato-Salinaro, A.3    Mirone, M.B.4    Amato, G.5    Belluardo, N.6
  • 34
    • 0025138986 scopus 로고
    • Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling
    • Cornell-Bell A.H., Finkbeiner S.M., Cooper M.S., Smith S.J. Glutamate induces calcium waves in cultured astrocytes: long-range glial signaling. Science 1990, 247:470-473.
    • (1990) Science , vol.247 , pp. 470-473
    • Cornell-Bell, A.H.1    Finkbeiner, S.M.2    Cooper, M.S.3    Smith, S.J.4
  • 35
    • 84862321615 scopus 로고    scopus 로고
    • Astrocytic regulation of glutamate homeostasis in epilepsy
    • Coulter D.A., Eid T. Astrocytic regulation of glutamate homeostasis in epilepsy. Glia 2012, 60:1215-1226.
    • (2012) Glia , vol.60 , pp. 1215-1226
    • Coulter, D.A.1    Eid, T.2
  • 36
    • 36448995383 scopus 로고    scopus 로고
    • Does glutamate released by astrocytes cause focal epilepsy?
    • D'Ambrosio R. Does glutamate released by astrocytes cause focal epilepsy?. Epilepsy Curr 2006, 6:173-176.
    • (2006) Epilepsy Curr , vol.6 , pp. 173-176
    • D'Ambrosio, R.1
  • 37
    • 0036089011 scopus 로고    scopus 로고
    • Differential role of KIR channel and Na(+)/K(+)-pump in the regulation of extracellular K(+) in rat hippocampus
    • D'Ambrosio R., Gordon D.S., Winn H.R. Differential role of KIR channel and Na(+)/K(+)-pump in the regulation of extracellular K(+) in rat hippocampus. J Neurophysiol 2002, 87:87-102.
    • (2002) J Neurophysiol , vol.87 , pp. 87-102
    • D'Ambrosio, R.1    Gordon, D.S.2    Winn, H.R.3
  • 38
    • 84864772658 scopus 로고    scopus 로고
    • Hippocampal tissue of patients with refractory temporal lobe epilepsy is associated with astrocyte activation, inflammation, and altered expression of channels and receptors
    • Das A., Wallace G.C., Holmes C., McDowell M.L., Smith J.A., Marshall J.D., Bonilha L., Edwards J.C., Glazier S.S., Ray S.K., Banik N.L. Hippocampal tissue of patients with refractory temporal lobe epilepsy is associated with astrocyte activation, inflammation, and altered expression of channels and receptors. Neuroscience 2012, 220:237-246.
    • (2012) Neuroscience , vol.220 , pp. 237-246
    • Das, A.1    Wallace, G.C.2    Holmes, C.3    McDowell, M.L.4    Smith, J.A.5    Marshall, J.D.6    Bonilha, L.7    Edwards, J.C.8    Glazier, S.S.9    Ray, S.K.10    Banik, N.L.11
  • 39
    • 69449102409 scopus 로고    scopus 로고
    • Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis?
    • David Y., Cacheaux L.P., Ivens S., Lapilover E., Heinemann U., Kaufer D., Friedman A. Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis?. J Neurosci 2009, 29:10588-10599.
    • (2009) J Neurosci , vol.29 , pp. 10588-10599
    • David, Y.1    Cacheaux, L.P.2    Ivens, S.3    Lapilover, E.4    Heinemann, U.5    Kaufer, D.6    Friedman, A.7
  • 41
    • 79955830747 scopus 로고    scopus 로고
    • Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway
    • Deng Q., Terunuma M., Fellin T., Moss S.J., Haydon P.G. Astrocytic activation of A1 receptors regulates the surface expression of NMDA receptors through a Src kinase dependent pathway. Glia 2011, 59:1084-1093.
    • (2011) Glia , vol.59 , pp. 1084-1093
    • Deng, Q.1    Terunuma, M.2    Fellin, T.3    Moss, S.J.4    Haydon, P.G.5
  • 42
    • 0019127095 scopus 로고
    • Transient changes in the size of the extracellular space in the sensorimotor cortex of cats in relation to stimulus-induced changes in potassium concentration
    • Dietzel I., Heinemann U., Hofmeier G., Lux H.D. Transient changes in the size of the extracellular space in the sensorimotor cortex of cats in relation to stimulus-induced changes in potassium concentration. Exp Brain Res 1980, 40:432-439.
    • (1980) Exp Brain Res , vol.40 , pp. 432-439
    • Dietzel, I.1    Heinemann, U.2    Hofmeier, G.3    Lux, H.D.4
  • 43
    • 35448989687 scopus 로고    scopus 로고
    • Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation
    • Djukic B., Casper K.B., Philpot B.D., Chin L.S., McCarthy K.D. Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation. J Neurosci 2007, 27:11354-11365.
    • (2007) J Neurosci , vol.27 , pp. 11354-11365
    • Djukic, B.1    Casper, K.B.2    Philpot, B.D.3    Chin, L.S.4    McCarthy, K.D.5
  • 44
    • 0025635679 scopus 로고
    • Osmolality-induced changes in extracellular volume alter epileptiform bursts independent of chemical synapses in the rat: importance of non-synaptic mechanisms in hippocampal epileptogenesis
    • Dudek F.E., Obenaus A., Tasker J.G. Osmolality-induced changes in extracellular volume alter epileptiform bursts independent of chemical synapses in the rat: importance of non-synaptic mechanisms in hippocampal epileptogenesis. Neurosci Lett 1990, 120:267-270.
    • (1990) Neurosci Lett , vol.120 , pp. 267-270
    • Dudek, F.E.1    Obenaus, A.2    Tasker, J.G.3
  • 45
    • 0034923094 scopus 로고    scopus 로고
    • The role and regulation of adenosine in the central nervous system
    • Dunwiddie T.V., Masino S.A. The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci 2001, 24:31-55.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 31-55
    • Dunwiddie, T.V.1    Masino, S.A.2
  • 46
    • 0027262604 scopus 로고
    • Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain
    • During M.J., Spencer D.D. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 1993, 341:1607-1610.
    • (1993) Lancet , vol.341 , pp. 1607-1610
    • During, M.J.1    Spencer, D.D.2
  • 50
    • 0031458058 scopus 로고    scopus 로고
    • Connexin 43 mRNA expression in two experimental models of epilepsy
    • Elisevich K., Rempel S.A., Smith B., Allar N. Connexin 43 mRNA expression in two experimental models of epilepsy. Mol Chem Neuropathol 1997, 32:75-88.
    • (1997) Mol Chem Neuropathol , vol.32 , pp. 75-88
    • Elisevich, K.1    Rempel, S.A.2    Smith, B.3    Allar, N.4
  • 51
    • 0032965372 scopus 로고    scopus 로고
    • Temporal profile of connexin 43 mRNA expression in a tetanus toxin-induced seizure disorder
    • Elisevich K., Rempel S.A., Smith B., Hirst K. Temporal profile of connexin 43 mRNA expression in a tetanus toxin-induced seizure disorder. Mol Chem Neuropathol 1998, 35:23-37.
    • (1998) Mol Chem Neuropathol , vol.35 , pp. 23-37
    • Elisevich, K.1    Rempel, S.A.2    Smith, B.3    Hirst, K.4
  • 52
    • 0031148871 scopus 로고    scopus 로고
    • Hippocampal connexin 43 expression in human complex partial seizure disorder
    • Elisevich K., Rempel S.A., Smith B.J., Edvardsen K. Hippocampal connexin 43 expression in human complex partial seizure disorder. Exp Neurol 1997, 145:154-164.
    • (1997) Exp Neurol , vol.145 , pp. 154-164
    • Elisevich, K.1    Rempel, S.A.2    Smith, B.J.3    Edvardsen, K.4
  • 53
    • 4444253508 scopus 로고    scopus 로고
    • Neurone-to-astrocyte signalling in the brain represents a distinct multifunctional unit
    • Fellin T., Carmignoto G. Neurone-to-astrocyte signalling in the brain represents a distinct multifunctional unit. J Physiol 2004, 559:3-15.
    • (2004) J Physiol , vol.559 , pp. 3-15
    • Fellin, T.1    Carmignoto, G.2
  • 54
    • 33748518188 scopus 로고    scopus 로고
    • Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices
    • Fellin T., Gomez-Gonzalo M., Gobbo S., Carmignoto G., Haydon P.G. Astrocytic glutamate is not necessary for the generation of epileptiform neuronal activity in hippocampal slices. J Neurosci 2006, 26:9312-9322.
    • (2006) J Neurosci , vol.26 , pp. 9312-9322
    • Fellin, T.1    Gomez-Gonzalo, M.2    Gobbo, S.3    Carmignoto, G.4    Haydon, P.G.5
  • 56
    • 4444320120 scopus 로고    scopus 로고
    • Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors
    • Fellin T., Pascual O., Gobbo S., Pozzan T., Haydon P.G., Carmignoto G. Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors. Neuron 2004, 43:729-743.
    • (2004) Neuron , vol.43 , pp. 729-743
    • Fellin, T.1    Pascual, O.2    Gobbo, S.3    Pozzan, T.4    Haydon, P.G.5    Carmignoto, G.6
  • 57
    • 0017251741 scopus 로고
    • The role of extracellular potassium in hippocampal epilepsy
    • Fisher R.S., Pedley T.A., Moody W.J., Prince D.A. The role of extracellular potassium in hippocampal epilepsy. Arch Neurol 1976, 33:76-83.
    • (1976) Arch Neurol , vol.33 , pp. 76-83
    • Fisher, R.S.1    Pedley, T.A.2    Moody, W.J.3    Prince, D.A.4
  • 58
    • 0036498359 scopus 로고    scopus 로고
    • Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy
    • Fonseca C.G., Green C.R., Nicholson L.F. Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy. Brain Res 2002, 929:105-116.
    • (2002) Brain Res , vol.929 , pp. 105-116
    • Fonseca, C.G.1    Green, C.R.2    Nicholson, L.F.3
  • 59
    • 0346103733 scopus 로고    scopus 로고
    • Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo
    • Gajda Z., Gyengesi E., Hermesz E., Ali K.S., Szente M. Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo. Epilepsia 2003, 44:1596-1600.
    • (2003) Epilepsia , vol.44 , pp. 1596-1600
    • Gajda, Z.1    Gyengesi, E.2    Hermesz, E.3    Ali, K.S.4    Szente, M.5
  • 60
    • 75649138386 scopus 로고    scopus 로고
    • Astroglial networks: a step further in neuroglial and gliovascular interactions
    • Giaume C., Koulakoff A., Roux L., Holcman D., Rouach N. Astroglial networks: a step further in neuroglial and gliovascular interactions. Nat Rev Neurosci 2010, 11:87-99.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 87-99
    • Giaume, C.1    Koulakoff, A.2    Roux, L.3    Holcman, D.4    Rouach, N.5
  • 61
    • 0031239423 scopus 로고    scopus 로고
    • Metabolic trafficking through astrocytic gap junctions
    • Giaume C., Tabernero A., Medina J.M. Metabolic trafficking through astrocytic gap junctions. Glia 1997, 21:114-123.
    • (1997) Glia , vol.21 , pp. 114-123
    • Giaume, C.1    Tabernero, A.2    Medina, J.M.3
  • 63
    • 0028845558 scopus 로고
    • Neurochemical and morphological changes associated with human epilepsy
    • Glass M., Dragunow M. Neurochemical and morphological changes associated with human epilepsy. Brain Res Rev 1995, 21:29-41.
    • (1995) Brain Res Rev , vol.21 , pp. 29-41
    • Glass, M.1    Dragunow, M.2
  • 65
    • 0037478606 scopus 로고    scopus 로고
    • Seizure suppression by adenosine A1 receptor activation in a mouse model of pharmacoresistant epilepsy
    • Gouder N., Fritschy J.M., Boison D. Seizure suppression by adenosine A1 receptor activation in a mouse model of pharmacoresistant epilepsy. Epilepsia 2003, 44:877-885.
    • (2003) Epilepsia , vol.44 , pp. 877-885
    • Gouder, N.1    Fritschy, J.M.2    Boison, D.3
  • 66
    • 0842284006 scopus 로고    scopus 로고
    • Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis
    • Gouder N., Scheurer L., Fritschy J.M., Boison D. Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis. J Neurosci 2004, 24:692-701.
    • (2004) J Neurosci , vol.24 , pp. 692-701
    • Gouder, N.1    Scheurer, L.2    Fritschy, J.M.3    Boison, D.4
  • 67
    • 74449091642 scopus 로고    scopus 로고
    • Abnormal expressions of glutamate transporters and metabotropic glutamate receptor 1 in the spontaneously epileptic rat hippocampus
    • Guo F., Sun F., Yu J.L., Wang Q.H., Tu D.Y., Mao X.Y., Liu R., Wu K.C., Xie N., Hao L.Y., Cai J.Q. Abnormal expressions of glutamate transporters and metabotropic glutamate receptor 1 in the spontaneously epileptic rat hippocampus. Brain Res Bull 2010, 81:510-516.
    • (2010) Brain Res Bull , vol.81 , pp. 510-516
    • Guo, F.1    Sun, F.2    Yu, J.L.3    Wang, Q.H.4    Tu, D.Y.5    Mao, X.Y.6    Liu, R.7    Wu, K.C.8    Xie, N.9    Hao, L.Y.10    Cai, J.Q.11
  • 68
    • 23044504422 scopus 로고    scopus 로고
    • Furosemide and mannitol suppression of epileptic activity in the human brain
    • Haglund M.M., Hochman D.W. Furosemide and mannitol suppression of epileptic activity in the human brain. J Neurophysiol 2005, 94:907-918.
    • (2005) J Neurophysiol , vol.94 , pp. 907-918
    • Haglund, M.M.1    Hochman, D.W.2
  • 69
    • 80052805065 scopus 로고    scopus 로고
    • Evidence that compromised K(+) spatial buffering contributes to the epileptogenic effect of mutations in the human kir4.1 gene (KCNJ10)
    • Haj-Yasein N.N., Jensen V., Vindedal G.F., Gundersen G.A., Klungland A., Ottersen O.P., Hvalby O., Nagelhus E.A. Evidence that compromised K(+) spatial buffering contributes to the epileptogenic effect of mutations in the human kir4.1 gene (KCNJ10). Glia 2011, 59:1635-1642.
    • (2011) Glia , vol.59 , pp. 1635-1642
    • Haj-Yasein, N.N.1    Jensen, V.2    Vindedal, G.F.3    Gundersen, G.A.4    Klungland, A.5    Ottersen, O.P.6    Hvalby, O.7    Nagelhus, E.A.8
  • 70
    • 33745873475 scopus 로고    scopus 로고
    • Astrocyte control of synaptic transmission and neurovascular coupling
    • Haydon P.G., Carmignoto G. Astrocyte control of synaptic transmission and neurovascular coupling. Physiol Rev 2006, 86:1009-1031.
    • (2006) Physiol Rev , vol.86 , pp. 1009-1031
    • Haydon, P.G.1    Carmignoto, G.2
  • 72
    • 0017329349 scopus 로고
    • Ceiling of stimulus induced rises in extracellular potassium concentration in the cerebral cortex of cat
    • Heinemann U., Lux H.D. Ceiling of stimulus induced rises in extracellular potassium concentration in the cerebral cortex of cat. Brain Res 1977, 120:231-249.
    • (1977) Brain Res , vol.120 , pp. 231-249
    • Heinemann, U.1    Lux, H.D.2
  • 73
    • 34848821581 scopus 로고    scopus 로고
    • Extracellular glutamate concentration in hippocampal slice
    • Herman M.A., Jahr C.E. Extracellular glutamate concentration in hippocampal slice. J Neurosci 2007, 27:9736-9741.
    • (2007) J Neurosci , vol.27 , pp. 9736-9741
    • Herman, M.A.1    Jahr, C.E.2
  • 74
    • 78751607023 scopus 로고    scopus 로고
    • Estimating risk for developing epilepsy:a population-based study in Rochester, Minnesota
    • Hesdorffer D.C., Logroscino G., Benn E.K., Katri N., Cascino G., Hauser W.A. Estimating risk for developing epilepsy:a population-based study in Rochester, Minnesota. Neurology 2011, 76:23-27.
    • (2011) Neurology , vol.76 , pp. 23-27
    • Hesdorffer, D.C.1    Logroscino, G.2    Benn, E.K.3    Katri, N.4    Cascino, G.5    Hauser, W.A.6
  • 78
    • 0036796629 scopus 로고    scopus 로고
    • Anticonvulsant actions of gap junctional blockers in an in vitro seizure model
    • Jahromi S.S., Wentlandt K., Piran S., Carlen P.L. Anticonvulsant actions of gap junctional blockers in an in vitro seizure model. J Neurophysiol 2002, 88:1893-1902.
    • (2002) J Neurophysiol , vol.88 , pp. 1893-1902
    • Jahromi, S.S.1    Wentlandt, K.2    Piran, S.3    Carlen, P.L.4
  • 79
    • 0037126962 scopus 로고    scopus 로고
    • Effects of barium, furosemide, ouabaine and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy
    • Jauch R., Windmuller O., Lehmann T.N., Heinemann U., Gabriel S. Effects of barium, furosemide, ouabaine and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy. Brain Res 2002, 925:18-27.
    • (2002) Brain Res , vol.925 , pp. 18-27
    • Jauch, R.1    Windmuller, O.2    Lehmann, T.N.3    Heinemann, U.4    Gabriel, S.5
  • 80
    • 0025393917 scopus 로고
    • Basic mechanisms of focal epilepsies
    • Jefferys J.G. Basic mechanisms of focal epilepsies. Exp Physiol 1990, 75:127-162.
    • (1990) Exp Physiol , vol.75 , pp. 127-162
    • Jefferys, J.G.1
  • 81
    • 84872251822 scopus 로고    scopus 로고
    • Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation
    • Jin B.J., Zhang H., Binder D.K., Verkman A.S. Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation. J Gen Physiol 2013, 141:119-132.
    • (2013) J Gen Physiol , vol.141 , pp. 119-132
    • Jin, B.J.1    Zhang, H.2    Binder, D.K.3    Verkman, A.S.4
  • 82
    • 34548178798 scopus 로고    scopus 로고
    • Excitatory synaptic transmission persists independently of the glutamate-glutamine cycle
    • Kam K., Nicoll R. Excitatory synaptic transmission persists independently of the glutamate-glutamine cycle. J Neurosci 2007, 27:9192-9200.
    • (2007) J Neurosci , vol.27 , pp. 9192-9200
    • Kam, K.1    Nicoll, R.2
  • 83
    • 28044436908 scopus 로고    scopus 로고
    • Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons
    • Kang N., Xu J., Xu Q., Nedergaard M., Kang J. Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons. J Neurophysiol 2005, 94:4121-4130.
    • (2005) J Neurophysiol , vol.94 , pp. 4121-4130
    • Kang, N.1    Xu, J.2    Xu, Q.3    Nedergaard, M.4    Kang, J.5
  • 84
    • 0030550364 scopus 로고    scopus 로고
    • Astrocytes in kindling: relevance to epileptogenesis
    • Khurgel M., Ivy G.O. Astrocytes in kindling: relevance to epileptogenesis. Epilepsy Res 1996, 26:163-175.
    • (1996) Epilepsy Res , vol.26 , pp. 163-175
    • Khurgel, M.1    Ivy, G.O.2
  • 86
    • 0034255132 scopus 로고    scopus 로고
    • Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: phenotypic impact in retina
    • Kofuji P., Ceelen P., Zahs K.R., Surbeck L.W., Lester H.A., Newman E.A. Genetic inactivation of an inwardly rectifying potassium channel (Kir4.1 subunit) in mice: phenotypic impact in retina. J Neurosci 2000, 20:5733-5740.
    • (2000) J Neurosci , vol.20 , pp. 5733-5740
    • Kofuji, P.1    Ceelen, P.2    Zahs, K.R.3    Surbeck, L.W.4    Lester, H.A.5    Newman, E.A.6
  • 87
    • 9344266325 scopus 로고    scopus 로고
    • Potassium buffering in the central nervous system
    • Kofuji P., Newman E.A. Potassium buffering in the central nervous system. Neuroscience 2004, 129:1045-1056.
    • (2004) Neuroscience , vol.129 , pp. 1045-1056
    • Kofuji, P.1    Newman, E.A.2
  • 88
    • 0035881407 scopus 로고    scopus 로고
    • Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling
    • Köhling R., Gladwell S.J., Bracci E., Vreugdenhil M., Jefferys J.G. Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling. Neuroscience 2001, 105:579-587.
    • (2001) Neuroscience , vol.105 , pp. 579-587
    • Köhling, R.1    Gladwell, S.J.2    Bracci, E.3    Vreugdenhil, M.4    Jefferys, J.G.5
  • 89
    • 33846862901 scopus 로고    scopus 로고
    • Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes
    • Kucheryavykh Y.V., Kucheryavykh L.Y., Nichols C.G., Maldonado H.M., Baksi K., Reichenbach A., Skatchkov S.N., Eaton M.J. Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes. Glia 2007, 55:274-281.
    • (2007) Glia , vol.55 , pp. 274-281
    • Kucheryavykh, Y.V.1    Kucheryavykh, L.Y.2    Nichols, C.G.3    Maldonado, H.M.4    Baksi, K.5    Reichenbach, A.6    Skatchkov, S.N.7    Eaton, M.J.8
  • 93
    • 84862782256 scopus 로고    scopus 로고
    • Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis
    • Lee D.J., Hsu M.S., Seldin M.M., Arellano J.L., Binder D.K. Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis. Exp Neurol 2012, 235:246-255.
    • (2012) Exp Neurol , vol.235 , pp. 246-255
    • Lee, D.J.1    Hsu, M.S.2    Seldin, M.M.3    Arellano, J.L.4    Binder, D.K.5
  • 94
    • 0029384918 scopus 로고
    • Human epileptic astrocytes exhibit increased gap junction coupling
    • Lee S.H., Magge S., Spencer D.D., Sontheimer H., Cornell-Bell A.H. Human epileptic astrocytes exhibit increased gap junction coupling. Glia 1995, 15:195-202.
    • (1995) Glia , vol.15 , pp. 195-202
    • Lee, S.H.1    Magge, S.2    Spencer, D.D.3    Sontheimer, H.4    Cornell-Bell, A.H.5
  • 96
    • 0035881359 scopus 로고    scopus 로고
    • Upregulation of gap junction connexin 32 with epileptiform activity in the isolated mouse hippocampus
    • Li J., Shen H., Naus C.C., Zhang L., Carlen P.L. Upregulation of gap junction connexin 32 with epileptiform activity in the isolated mouse hippocampus. Neuroscience 2001, 105:589-598.
    • (2001) Neuroscience , vol.105 , pp. 589-598
    • Li, J.1    Shen, H.2    Naus, C.C.3    Zhang, L.4    Carlen, P.L.5
  • 97
    • 70350440498 scopus 로고    scopus 로고
    • Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice
    • Li T., Lan J.Q., Boison D. Uncoupling of astrogliosis from epileptogenesis in adenosine kinase (ADK) transgenic mice. Neuron Glia Biol 2008, 4:91-99.
    • (2008) Neuron Glia Biol , vol.4 , pp. 91-99
    • Li, T.1    Lan, J.Q.2    Boison, D.3
  • 98
    • 33748203626 scopus 로고    scopus 로고
    • Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hippocampal area CA1
    • Liang S.L., Carlson G.C., Coulter D.A. Dynamic regulation of synaptic GABA release by the glutamate-glutamine cycle in hippocampal area CA1. J Neurosci 2006, 26:8537-8548.
    • (2006) J Neurosci , vol.26 , pp. 8537-8548
    • Liang, S.L.1    Carlson, G.C.2    Coulter, D.A.3
  • 99
    • 84879463258 scopus 로고    scopus 로고
    • Time-dependent modulation of AMPA receptor phosphorylation and mRNA expression of NMDA receptors and glial glutamate transporters in the rat hippocampus and cerebral cortex in a pilocarpine model of epilepsy
    • Lopes M.W., Soares F.M., de Mello N., Nunes J.C., Cajado A.G., de Brito D., de Cordova F.M., da Cunha R.M., Walz R., Leal R.B. Time-dependent modulation of AMPA receptor phosphorylation and mRNA expression of NMDA receptors and glial glutamate transporters in the rat hippocampus and cerebral cortex in a pilocarpine model of epilepsy. Exp Brain Res 2013, 226:153-163.
    • (2013) Exp Brain Res , vol.226 , pp. 153-163
    • Lopes, M.W.1    Soares, F.M.2    de Mello, N.3    Nunes, J.C.4    Cajado, A.G.5    de Brito, D.6    de Cordova, F.M.7    da Cunha, R.M.8    Walz, R.9    Leal, R.B.10
  • 101
    • 84907200996 scopus 로고    scopus 로고
    • GABAergic interneuron to astrocyte signalling: a neglected form of cell communication in the brain
    • Losi G., Mariotti L., Carmignoto G. GABAergic interneuron to astrocyte signalling: a neglected form of cell communication in the brain. Philos Trans R Soc Lond B Biol Sci 2014, 369(1654):20130609.
    • (2014) Philos Trans R Soc Lond B Biol Sci , vol.369 , Issue.1654 , pp. 20130609
    • Losi, G.1    Mariotti, L.2    Carmignoto, G.3
  • 102
    • 0017195383 scopus 로고
    • Functions of primary afferents and responses of extracellular K+ during spinal epileptiform seizures
    • Lothman E.W., Somjen G.G. Functions of primary afferents and responses of extracellular K+ during spinal epileptiform seizures. Electroencephalogr Clin Neurophysiol 1976, 41:253-267.
    • (1976) Electroencephalogr Clin Neurophysiol , vol.41 , pp. 253-267
    • Lothman, E.W.1    Somjen, G.G.2
  • 103
    • 0017579832 scopus 로고
    • Glutamine synthetase: glial localization in brain
    • Martinez-Hernandez A., Bell K.P., Norenberg M.D. Glutamine synthetase: glial localization in brain. Science 1977, 195:1356-1358.
    • (1977) Science , vol.195 , pp. 1356-1358
    • Martinez-Hernandez, A.1    Bell, K.P.2    Norenberg, M.D.3
  • 105
    • 0025002972 scopus 로고
    • Regional variation of extracellular space in the hippocampus
    • McBain C.J., Traynelis S.F., Dingledine R. Regional variation of extracellular space in the hippocampus. Science 1990, 249(4969):674-677.
    • (1990) Science , vol.249 , Issue.4969 , pp. 674-677
    • McBain, C.J.1    Traynelis, S.F.2    Dingledine, R.3
  • 106
    • 78650425783 scopus 로고    scopus 로고
    • Aquaporin 4 expression in control and epileptic human cerebral cortex
    • Medici V., Frassoni C., Tassi L., Spreafico R., Garbelli R. Aquaporin 4 expression in control and epileptic human cerebral cortex. Brain Res 2011, 1367:330-339.
    • (2011) Brain Res , vol.1367 , pp. 330-339
    • Medici, V.1    Frassoni, C.2    Tassi, L.3    Spreafico, R.4    Garbelli, R.5
  • 107
    • 36549007384 scopus 로고    scopus 로고
    • Antiepileptic effect of carbenoxolone on seizures induced by 4-aminopyridine: a study in the rat hippocampus and entorhinal cortex
    • Medina-Ceja L., Cordero-Romero A., Morales-Villagran A. Antiepileptic effect of carbenoxolone on seizures induced by 4-aminopyridine: a study in the rat hippocampus and entorhinal cortex. Brain Res 2008, 1187:74-81.
    • (2008) Brain Res , vol.1187 , pp. 74-81
    • Medina-Ceja, L.1    Cordero-Romero, A.2    Morales-Villagran, A.3
  • 108
    • 0028535070 scopus 로고
    • The role of glutamate in epilepsy and other CNS disorders
    • Meldrum B.S. The role of glutamate in epilepsy and other CNS disorders. Neurology 1994, 44:14-23.
    • (1994) Neurology , vol.44 , pp. 14-23
    • Meldrum, B.S.1
  • 109
    • 0032956181 scopus 로고    scopus 로고
    • Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system
    • Mensah-Nyagan A.G., Do-Rego J.L., Beaujean D., Luu-The V., Pelletier G., Vaudry H. Neurosteroids: expression of steroidogenic enzymes and regulation of steroid biosynthesis in the central nervous system. Pharmacol Rev 1999, 51:63-81.
    • (1999) Pharmacol Rev , vol.51 , pp. 63-81
    • Mensah-Nyagan, A.G.1    Do-Rego, J.L.2    Beaujean, D.3    Luu-The, V.4    Pelletier, G.5    Vaudry, H.6
  • 110
    • 0030939042 scopus 로고    scopus 로고
    • Alterations in glutamate transporter protein levels in kindling-induced epilepsy
    • Miller H.P., Levey A.I., Rothstein J.D., Tzingounis A.V., Conn P.J. Alterations in glutamate transporter protein levels in kindling-induced epilepsy. J Neurochem 1997, 68:1564-1570.
    • (1997) J Neurochem , vol.68 , pp. 1564-1570
    • Miller, H.P.1    Levey, A.I.2    Rothstein, J.D.3    Tzingounis, A.V.4    Conn, P.J.5
  • 111
    • 0015979851 scopus 로고
    • Extracellular potassium activity during epileptogenesis
    • Moody W.J., Futamachi K.J., Prince D.A. Extracellular potassium activity during epileptogenesis. Exp Neurol 1974, 42:248-263.
    • (1974) Exp Neurol , vol.42 , pp. 248-263
    • Moody, W.J.1    Futamachi, K.J.2    Prince, D.A.3
  • 113
    • 0033104066 scopus 로고    scopus 로고
    • Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Muller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains
    • Nagelhus E.A., Horio Y., Inanobe A., Fujita A., Haug F.M., Nielsen S., Kurachi Y., Ottersen O.P. Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Muller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains. Glia 1999, 26:47-54.
    • (1999) Glia , vol.26 , pp. 47-54
    • Nagelhus, E.A.1    Horio, Y.2    Inanobe, A.3    Fujita, A.4    Haug, F.M.5    Nielsen, S.6    Kurachi, Y.7    Ottersen, O.P.8
  • 114
    • 0034067910 scopus 로고    scopus 로고
    • Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS
    • Nagy J.I., Rash J.E. Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS. Brain Res Rev 2000, 32:29-44.
    • (2000) Brain Res Rev , vol.32 , pp. 29-44
    • Nagy, J.I.1    Rash, J.E.2
  • 115
    • 0026090172 scopus 로고
    • Gap junction gene expression in human seizure disorder
    • Naus C.C.G., Bechberger J.F., Paul D.L. Gap junction gene expression in human seizure disorder. Exp Neurol 1991, 111:198-203.
    • (1991) Exp Neurol , vol.111 , pp. 198-203
    • Naus, C.C.G.1    Bechberger, J.F.2    Paul, D.L.3
  • 116
    • 11144271430 scopus 로고    scopus 로고
    • Emerging role of gap junctions in epilepsy
    • Nemani V.M., Binder D.K. Emerging role of gap junctions in epilepsy. Histol Histopathol 2005, 20:253-259.
    • (2005) Histol Histopathol , vol.20 , pp. 253-259
    • Nemani, V.M.1    Binder, D.K.2
  • 117
    • 0035425966 scopus 로고    scopus 로고
    • Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination
    • Neusch C., Rozengurt N., Jacobs R.E., Lester H.A., Kofuji P. Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination. J Neurosci 2001, 21:5429-5438.
    • (2001) J Neurosci , vol.21 , pp. 5429-5438
    • Neusch, C.1    Rozengurt, N.2    Jacobs, R.E.3    Lester, H.A.4    Kofuji, P.5
  • 118
    • 0013926565 scopus 로고
    • Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia
    • Orkand R.K., Nicholls J.G., Kuffler S.W. Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. J Neurophysiol 1966, 29:788-806.
    • (1966) J Neurophysiol , vol.29 , pp. 788-806
    • Orkand, R.K.1    Nicholls, J.G.2    Kuffler, S.W.3
  • 120
    • 0032531028 scopus 로고    scopus 로고
    • Anion currents and predicted glutamate flux through a neuronal glutamate transporter
    • Otis T.S., Jahr C.E. Anion currents and predicted glutamate flux through a neuronal glutamate transporter. J Neurosci 1998, 18:7099-7110.
    • (1998) J Neurosci , vol.18 , pp. 7099-7110
    • Otis, T.S.1    Jahr, C.E.2
  • 121
    • 28544440151 scopus 로고    scopus 로고
    • K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator
    • Padmawar P., Yao X., Bloch O., Manley G.T., Verkman A.S. K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. Nat Methods 2005, 2:825-827.
    • (2005) Nat Methods , vol.2 , pp. 825-827
    • Padmawar, P.1    Yao, X.2    Bloch, O.3    Manley, G.T.4    Verkman, A.S.5
  • 122
    • 0029944481 scopus 로고    scopus 로고
    • Influence of osmolality on seizure amplitude and propagation in the rat dentate gyrus
    • Pan E., Stringer J.L. Influence of osmolality on seizure amplitude and propagation in the rat dentate gyrus. Neurosci Lett 1996, 207:9-12.
    • (1996) Neurosci Lett , vol.207 , pp. 9-12
    • Pan, E.1    Stringer, J.L.2
  • 123
    • 84879696907 scopus 로고    scopus 로고
    • Emerging role for astroglial networks in information processing: from synapse to behavior
    • Pannasch U., Rouach N. Emerging role for astroglial networks in information processing: from synapse to behavior. Trends Neurosci 2013, 36:405-417.
    • (2013) Trends Neurosci , vol.36 , pp. 405-417
    • Pannasch, U.1    Rouach, N.2
  • 125
    • 84875414010 scopus 로고    scopus 로고
    • Aquaporin water channels in the nervous system
    • Papadopoulos M.C., Verkman A.S. Aquaporin water channels in the nervous system. Nat Rev Neurosci 2013, 14:265-277.
    • (2013) Nat Rev Neurosci , vol.14 , pp. 265-277
    • Papadopoulos, M.C.1    Verkman, A.S.2
  • 126
    • 80052814456 scopus 로고    scopus 로고
    • Redistribution of astrocytic glutamine synthetase in the hippocampus of chronic epileptic rats
    • Papageorgiou I.E., Gabriel S., Fetani A.F., Kann O., Heinemann U. Redistribution of astrocytic glutamine synthetase in the hippocampus of chronic epileptic rats. Glia 2011, 59:1706-1718.
    • (2011) Glia , vol.59 , pp. 1706-1718
    • Papageorgiou, I.E.1    Gabriel, S.2    Fetani, A.F.3    Kann, O.4    Heinemann, U.5
  • 128
    • 14644388122 scopus 로고    scopus 로고
    • Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes
    • Perea G., Araque A. Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes. J Neurosci 2005, 25:2192-2203.
    • (2005) J Neurosci , vol.25 , pp. 2192-2203
    • Perea, G.1    Araque, A.2
  • 129
    • 0028343428 scopus 로고
    • Modulation of gap junctional mechanisms during calcium-free induced field burst activity: a possible role for electrotonic coupling in epileptogenesis
    • Perez-Velazquez J.L., Valiante T.A., Carlen P.L. Modulation of gap junctional mechanisms during calcium-free induced field burst activity: a possible role for electrotonic coupling in epileptogenesis. J Neurosci 1994, 14:4308-4317.
    • (1994) J Neurosci , vol.14 , pp. 4308-4317
    • Perez-Velazquez, J.L.1    Valiante, T.A.2    Carlen, P.L.3
  • 130
    • 84892432033 scopus 로고    scopus 로고
    • Genetic association of KCNJ10 rs1130183 with seizure susceptibility and computational analysis of deleterious non-synonymous SNPs of KCNJ10 gene
    • Phani N.M., Acharya S., Xavy S., Bhaskaranand N., Bhat M.K., Jain A., Rai P.S., Satyamoorthy K. Genetic association of KCNJ10 rs1130183 with seizure susceptibility and computational analysis of deleterious non-synonymous SNPs of KCNJ10 gene. Gene 2014, 536:247-253.
    • (2014) Gene , vol.536 , pp. 247-253
    • Phani, N.M.1    Acharya, S.2    Xavy, S.3    Bhaskaranand, N.4    Bhat, M.K.5    Jain, A.6    Rai, P.S.7    Satyamoorthy, K.8
  • 131
    • 24744449310 scopus 로고    scopus 로고
    • Initiation, propagation, and termination of epileptiform activity in rodent neocortex in vitro involve distinct mechanisms
    • Pinto D.J., Patrick S.L., Huang W.C., Connors B.W. Initiation, propagation, and termination of epileptiform activity in rodent neocortex in vitro involve distinct mechanisms. J Neurosci 2005, 25:8131-8140.
    • (2005) J Neurosci , vol.25 , pp. 8131-8140
    • Pinto, D.J.1    Patrick, S.L.2    Huang, W.C.3    Connors, B.W.4
  • 135
    • 84890947554 scopus 로고    scopus 로고
    • Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1
    • Raphemot R., Kadakia R.J., Olsen M.L., Banerjee S., Days E., Smith S.S., Weaver C.D., Denton J.S. Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1. Assay Drug Dev Technol 2013, 11:532-543.
    • (2013) Assay Drug Dev Technol , vol.11 , pp. 532-543
    • Raphemot, R.1    Kadakia, R.J.2    Olsen, M.L.3    Banerjee, S.4    Days, E.5    Smith, S.S.6    Weaver, C.D.7    Denton, J.S.8
  • 136
    • 78649361562 scopus 로고    scopus 로고
    • Neurosteroids: endogenous role in the human brain and therapeutic potentials1
    • Reddy D.S. Neurosteroids: endogenous role in the human brain and therapeutic potentials1. Prog Brain Res 2010, 186:113-137.
    • (2010) Prog Brain Res , vol.186 , pp. 113-137
    • Reddy, D.S.1
  • 138
    • 0026543575 scopus 로고
    • Osmolality and nonsynaptic epileptiform bursts in rat CA1 and dentate gyrus
    • Roper S.N., Obenaus A., Dudek F.E. Osmolality and nonsynaptic epileptiform bursts in rat CA1 and dentate gyrus. Ann Neurol 1992, 31:81-85.
    • (1992) Ann Neurol , vol.31 , pp. 81-85
    • Roper, S.N.1    Obenaus, A.2    Dudek, F.E.3
  • 139
    • 0034638489 scopus 로고    scopus 로고
    • Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices
    • Ross F.M., Gwyn P., Spanswick D., Davies S.N. Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices. Neuroscience 2000, 100:789-796.
    • (2000) Neuroscience , vol.100 , pp. 789-796
    • Ross, F.M.1    Gwyn, P.2    Spanswick, D.3    Davies, S.N.4
  • 141
    • 57349185900 scopus 로고    scopus 로고
    • Astroglial metabolic networks sustain hippocampal synaptic transmission
    • Rouach N., Koulakoff A., Abudara V., Willecke K., Giaume C. Astroglial metabolic networks sustain hippocampal synaptic transmission. Science 2008, 322:1551-1555.
    • (2008) Science , vol.322 , pp. 1551-1555
    • Rouach, N.1    Koulakoff, A.2    Abudara, V.3    Willecke, K.4    Giaume, C.5
  • 142
    • 34547568729 scopus 로고    scopus 로고
    • Evidence against functional interaction between aquaporin-4 water channels and Kir4.1 K+ channels in retinal muller cells
    • Ruiz-Ederra J., Zhang H., Verkman A.S. Evidence against functional interaction between aquaporin-4 water channels and Kir4.1 K+ channels in retinal muller cells. J Biol Chem 2007, 282:21866-21872.
    • (2007) J Biol Chem , vol.282 , pp. 21866-21872
    • Ruiz-Ederra, J.1    Zhang, H.2    Verkman, A.S.3
  • 143
    • 41149164595 scopus 로고    scopus 로고
    • Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures
    • Samoilova M., Wentlandt K., Adamchik Y., Velumian A.A., Carlen P.L. Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures. Exp Neurol 2008, 210:762-775.
    • (2008) Exp Neurol , vol.210 , pp. 762-775
    • Samoilova, M.1    Wentlandt, K.2    Adamchik, Y.3    Velumian, A.A.4    Carlen, P.L.5
  • 144
    • 0041802936 scopus 로고    scopus 로고
    • Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression
    • Samoilova M., Li J., Pelletier M.R., Wentlandt K., Adamchik Y., Naus C.C., Carlen P.L. Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression. J Neurochem 2003, 86:687-699.
    • (2003) J Neurochem , vol.86 , pp. 687-699
    • Samoilova, M.1    Li, J.2    Pelletier, M.R.3    Wentlandt, K.4    Adamchik, Y.5    Naus, C.C.6    Carlen, P.L.7
  • 145
    • 63449118968 scopus 로고    scopus 로고
    • Excitatory amino acid transporters EAAT-1 and EAAT-2 in temporal lobe and hippocampus in intractable temporal lobe epilepsy
    • Sarac S., Afzal S., Broholm H., Madsen F.F., Ploug T., Laursen H. Excitatory amino acid transporters EAAT-1 and EAAT-2 in temporal lobe and hippocampus in intractable temporal lobe epilepsy. APMIS 2009, 117:291-301.
    • (2009) APMIS , vol.117 , pp. 291-301
    • Sarac, S.1    Afzal, S.2    Broholm, H.3    Madsen, F.F.4    Ploug, T.5    Laursen, H.6
  • 146
    • 33750368810 scopus 로고    scopus 로고
    • Astrocyte calcium waves: what they are and what they do
    • Scemes E., Giaume C. Astrocyte calcium waves: what they are and what they do. Glia 2006, 54:716-725.
    • (2006) Glia , vol.54 , pp. 716-725
    • Scemes, E.1    Giaume, C.2
  • 147
    • 0032171277 scopus 로고    scopus 로고
    • Increased intercellular communication in mouse astrocytes exposed to hyposmotic shocks
    • Scemes E., Spray D.C. Increased intercellular communication in mouse astrocytes exposed to hyposmotic shocks. Glia 1998, 24:74-84.
    • (1998) Glia , vol.24 , pp. 74-84
    • Scemes, E.1    Spray, D.C.2
  • 149
    • 0033811922 scopus 로고    scopus 로고
    • Functional and molecular properties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy
    • Schröder W., Hinterkeuser S., Seifert G., Schramm J., Jabs R., Wilkin G.P., Steinhäuser C. Functional and molecular properties of human astrocytes in acute hippocampal slices obtained from patients with temporal lobe epilepsy. Epilepsia 2000, 41:181-184.
    • (2000) Epilepsia , vol.41 , pp. 181-184
    • Schröder, W.1    Hinterkeuser, S.2    Seifert, G.3    Schramm, J.4    Jabs, R.5    Wilkin, G.P.6    Steinhäuser, C.7
  • 150
    • 0022472326 scopus 로고
    • Differential effect of adenosine on pre-and postsynaptic calcium fuxes
    • Schubert P., Heinemann U., Kolb R. Differential effect of adenosine on pre-and postsynaptic calcium fuxes. Brain Res 1986, 376:382-386.
    • (1986) Brain Res , vol.376 , pp. 382-386
    • Schubert, P.1    Heinemann, U.2    Kolb, R.3
  • 151
    • 0032167479 scopus 로고    scopus 로고
    • Osmolarity, ionic flux, and changes in brain excitability
    • Schwartzkroin P.A., Baraban S.C., Hochman D.W. Osmolarity, ionic flux, and changes in brain excitability. Epilepsy Res 1998, 32:275-285.
    • (1998) Epilepsy Res , vol.32 , pp. 275-285
    • Schwartzkroin, P.A.1    Baraban, S.C.2    Hochman, D.W.3
  • 153
    • 33644519960 scopus 로고    scopus 로고
    • Astrocyte dysfunction in neurological disorders: a molecular perspective
    • Seifert G., Schilling K., Steinhäuser C. Astrocyte dysfunction in neurological disorders: a molecular perspective. Nat Rev Neurosci 2006, 7:194-206.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 194-206
    • Seifert, G.1    Schilling, K.2    Steinhäuser, C.3
  • 154
    • 84877601668 scopus 로고    scopus 로고
    • Neuron-astrocyte signaling and epilepsy
    • Seifert G., Steinhäuser C. Neuron-astrocyte signaling and epilepsy. Exp Neurol 2013, 244:4-10.
    • (2013) Exp Neurol , vol.244 , pp. 4-10
    • Seifert, G.1    Steinhäuser, C.2
  • 155
    • 48549083976 scopus 로고    scopus 로고
    • Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons
    • Shigetomi E., Bowser D.N., Sofroniew M.V., Khakh B.S. Two forms of astrocyte calcium excitability have distinct effects on NMDA receptor-mediated slow inward currents in pyramidal neurons. J Neurosci 2008, 28:6659-6663.
    • (2008) J Neurosci , vol.28 , pp. 6659-6663
    • Shigetomi, E.1    Bowser, D.N.2    Sofroniew, M.V.3    Khakh, B.S.4
  • 157
    • 0034634721 scopus 로고    scopus 로고
    • Expression of connexin genes in hippocampus of kainate-treated and kindled rats under conditions of experimental epilepsy
    • Söhl G., Güldenagel M., Beck H., Teubner B., Traub O., Gutierrez R., Heinemann U., Willecke K. Expression of connexin genes in hippocampus of kainate-treated and kindled rats under conditions of experimental epilepsy. Mol Brain Res 2000, 83:44-51.
    • (2000) Mol Brain Res , vol.83 , pp. 44-51
    • Söhl, G.1    Güldenagel, M.2    Beck, H.3    Teubner, B.4    Traub, O.5    Gutierrez, R.6    Heinemann, U.7    Willecke, K.8
  • 158
    • 84862327508 scopus 로고    scopus 로고
    • Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling
    • Steinhäuser C., Seifert G., Bedner P. Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling. Glia 2012, 60:1192-1202.
    • (2012) Glia , vol.60 , pp. 1192-1202
    • Steinhäuser, C.1    Seifert, G.2    Bedner, P.3
  • 159
    • 79954590727 scopus 로고    scopus 로고
    • Impact of aquaporin-4 channels on K(+) buffering and gap junction coupling in the hippocampus
    • Strohschein S., Hüttmann K., Gabriel S., Binder D.K., Heinemann U., Steinhäuser C. Impact of aquaporin-4 channels on K(+) buffering and gap junction coupling in the hippocampus. Glia 2011, 59:973-980.
    • (2011) Glia , vol.59 , pp. 973-980
    • Strohschein, S.1    Hüttmann, K.2    Gabriel, S.3    Binder, D.K.4    Heinemann, U.5    Steinhäuser, C.6
  • 160
    • 0037121622 scopus 로고    scopus 로고
    • Involvement of electrical coupling in the in vivo ictal epileptiform activity induced by 4-aminopyridine in the neocortex
    • Szente M., Gajda Z., Said A.K., Hermesz E. Involvement of electrical coupling in the in vivo ictal epileptiform activity induced by 4-aminopyridine in the neocortex. Neuroscience 2002, 115:1067-1078.
    • (2002) Neuroscience , vol.115 , pp. 1067-1078
    • Szente, M.1    Gajda, Z.2    Said, A.K.3    Hermesz, E.4
  • 161
    • 77957763712 scopus 로고    scopus 로고
    • Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus
    • Takahashi D.K., Vargas J.R., Wilcox K.S. Increased coupling and altered glutamate transport currents in astrocytes following kainic-acid-induced status epilepticus. Neurobiol Dis 2010, 40:573-585.
    • (2010) Neurobiol Dis , vol.40 , pp. 573-585
    • Takahashi, D.K.1    Vargas, J.R.2    Wilcox, K.S.3
  • 165
    • 0020079720 scopus 로고
    • Cellular mechanism of neuronal synchronization in epilepsy
    • Traub R.D., Wong R.K. Cellular mechanism of neuronal synchronization in epilepsy. Science 1982, 216:745-747.
    • (1982) Science , vol.216 , pp. 745-747
    • Traub, R.D.1    Wong, R.K.2
  • 166
    • 0023833119 scopus 로고
    • Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice
    • Traynelis S.F., Dingledine R. Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice. J Neurophysiol 1988, 59:259-276.
    • (1988) J Neurophysiol , vol.59 , pp. 259-276
    • Traynelis, S.F.1    Dingledine, R.2
  • 167
    • 0024591823 scopus 로고
    • Role of extracellular space in hyperosmotic suppression of potassium-induced electrographic seizures
    • Traynelis S.F., Dingledine R. Role of extracellular space in hyperosmotic suppression of potassium-induced electrographic seizures. J Neurophysiol 1989, 61:927-938.
    • (1989) J Neurophysiol , vol.61 , pp. 927-938
    • Traynelis, S.F.1    Dingledine, R.2
  • 168
    • 33845253180 scopus 로고    scopus 로고
    • Modular propagation of epileptiform activity: evidence for an inhibitory veto in neocortex
    • Trevelyan A.J., Sussillo D., Watson B.O., Yuste R. Modular propagation of epileptiform activity: evidence for an inhibitory veto in neocortex. J Neurosci 2006, 26:12447-12455.
    • (2006) J Neurosci , vol.26 , pp. 12447-12455
    • Trevelyan, A.J.1    Sussillo, D.2    Watson, B.O.3    Yuste, R.4
  • 169
    • 0034083370 scopus 로고    scopus 로고
    • Expression of metabotropic glutamate receptor 5 is increased astrocytes after kainate-induced epileptic seizures
    • Ulas J., Satou T., Ivins K.J., Kesslak J.P., Cotman C.W., Balázs R. Expression of metabotropic glutamate receptor 5 is increased astrocytes after kainate-induced epileptic seizures. Glia 2000, 30:352-361.
    • (2000) Glia , vol.30 , pp. 352-361
    • Ulas, J.1    Satou, T.2    Ivins, K.J.3    Kesslak, J.P.4    Cotman, C.W.5    Balázs, R.6
  • 171
    • 68149174964 scopus 로고    scopus 로고
    • Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice
    • Voss L.J., Jacobson G., Sleigh J.W., Steyn-Ross A., Steyn-Ross M. Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice. Epilepsia 2009, 50:1971-1978.
    • (2009) Epilepsia , vol.50 , pp. 1971-1978
    • Voss, L.J.1    Jacobson, G.2    Sleigh, J.W.3    Steyn-Ross, A.4    Steyn-Ross, M.5
  • 172
    • 33745003688 scopus 로고    scopus 로고
    • The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus
    • Wallraff A., Köhling R., Heinemann U., Theis M., Willecke K., Steinhäuser C. The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus. J Neurosci 2006, 26:5438-5447.
    • (2006) J Neurosci , vol.26 , pp. 5438-5447
    • Wallraff, A.1    Köhling, R.2    Heinemann, U.3    Theis, M.4    Willecke, K.5    Steinhäuser, C.6
  • 173
    • 0033953257 scopus 로고    scopus 로고
    • Role of astrocytes in the clearance of excess extracellular potassium
    • Walz W. Role of astrocytes in the clearance of excess extracellular potassium. Neurochem Int 2000, 36:291-300.
    • (2000) Neurochem Int , vol.36 , pp. 291-300
    • Walz, W.1
  • 174
    • 71549141314 scopus 로고    scopus 로고
    • The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroencephalographic study
    • Wang Y., Zaveri H.P., Lee T.S., Eid T. The development of recurrent seizures after continuous intrahippocampal infusion of methionine sulfoximine in rats: a video-intracranial electroencephalographic study. Exp Neurol 2009, 220:293-302.
    • (2009) Exp Neurol , vol.220 , pp. 293-302
    • Wang, Y.1    Zaveri, H.P.2    Lee, T.S.3    Eid, T.4
  • 177
    • 0028243567 scopus 로고
    • Adenosine inhibits evoked synaptic transmission primarily by reducing presynaptic calcium influx in area CA1 of hippocampus
    • Wu L.G., Saggau P. Adenosine inhibits evoked synaptic transmission primarily by reducing presynaptic calcium influx in area CA1 of hippocampus. Neuron 1994, 12:1139-1148.
    • (1994) Neuron , vol.12 , pp. 1139-1148
    • Wu, L.G.1    Saggau, P.2
  • 178
    • 64449086356 scopus 로고    scopus 로고
    • Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex
    • Xu L., Zeng L.H., Wong M. Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex. Neurobiol Dis 2009, 34:291-299.
    • (2009) Neurobiol Dis , vol.34 , pp. 291-299
    • Xu, L.1    Zeng, L.H.2    Wong, M.3
  • 179
    • 45849123870 scopus 로고    scopus 로고
    • Aquaporin-4-deficient mice have increased extracellular space without tortuosity change
    • Yao X., Hrabetova S., Nicholson C., Manley G.T. Aquaporin-4-deficient mice have increased extracellular space without tortuosity change. J Neurosci 2008, 28:5460-5464.
    • (2008) J Neurosci , vol.28 , pp. 5460-5464
    • Yao, X.1    Hrabetova, S.2    Nicholson, C.3    Manley, G.T.4
  • 180
    • 37349023952 scopus 로고    scopus 로고
    • Aquaporin-4 independent Kir4.1 K+ channel function in brain glial cells
    • Zhang H., Verkman A.S. Aquaporin-4 independent Kir4.1 K+ channel function in brain glial cells. Mol Cell Neurosci 2008, 37:1-10.
    • (2008) Mol Cell Neurosci , vol.37 , pp. 1-10
    • Zhang, H.1    Verkman, A.S.2
  • 181
    • 0014241442 scopus 로고
    • Hippocampal epileptic activity induced by localized ventricular perfusion with high-potassium cerebrospinal fluid
    • Zuckermann E.C., Glaser G.H. Hippocampal epileptic activity induced by localized ventricular perfusion with high-potassium cerebrospinal fluid. Exp Neurol 1968, 20:87-110.
    • (1968) Exp Neurol , vol.20 , pp. 87-110
    • Zuckermann, E.C.1    Glaser, G.H.2


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