The effects of octanol on penicillin induced epileptiform activity in rats: An in vivo study

Epilepsy Research

Volumn 71, Issue 2-3, 2006, Pages 188-194

  Bostanci, M Ömer ^a   Baǧirici, Faruk ^a  

^a ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

Electroencephalography; Epileptic activity; Gap junctions; Octanol; Penicillin

Indexed keywords

OCTANOL; PENICILLIN G;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANNULATION; CONTROLLED STUDY; DRUG EFFECT; ELECTROENCEPHALOGRAM; EPILEPSY; EPILEPTIC DISCHARGE; GAP JUNCTION; GENERAL ANESTHESIA; IN VIVO STUDY; MALE; MONITORING; NONHUMAN; PRIORITY JOURNAL; RAT; RECORDING; SYNAPSE;

ANIMALS; ANTICONVULSANTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRODES, IMPLANTED; ELECTROENCEPHALOGRAPHY; MALE; OCTANOLS; PENICILLIN G; RATS; RATS, WISTAR; SEIZURES;

EID: 33748759806     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2006.06.010     Document Type: Article

References (34)

1. Aronica E., Gorter J.A., Jansen G.H., Leenstra S., Yankaya B., and Troost D. Expression of connexin43 and connexin32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex. Acta Neuropathol. 101 (2001) 449-459
2. Bagirici F., Gokce F.M., Demir S., and Marangoz C. Calcium channel blocker flunarizine suppresses epileptiform activity induced by penicillin in rats. Neurosci. Res. Commun. 28 2 (2001) 135-140
3. Carlen P.L., Skinner F., Zhang L., Naus C., Kushnir M., and Perez-Velazquez J. The role of gap junctions in seizures. Brain Res. Rev. 32 (2000) 235-241
4. Connors B.W., and Long M.A. Electrical synapses in the mammalian brain. Annu. Rev. Neurosci. 27 (2004) 394-418
5. De Curtis M., Manfridi A., and Biella G. Activity-dependent pH shifts and periodic recurrence of spontaneous interictal spikes in a model of focal epileptogenesis. J. Neurosci. 18 (1998) 7543-7551
6. Dermietzel R., and Spary D.C. Gap junctions in the brain: where, what type, how many and why. Trends Neurosci. 16 (1993) 186-192
7. Gajda Z., Gyengesi E., Hermesz E., Ali K.S., and Szente M. Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo. Epilepsia 44 (2003) 1596-1600
8. Giaume C., Fromaget C., el Aoumari A., Cordier J., Glowinski J., and Gros D. Gap junctions in cultured astrocytes: single-channel currents and characterization of channel-forming protein. Neuron 6 (1991) 133-143
9. Jahromi S.S., Wentlandt K., Piran S., and Carlen P.L. Anticonvulsant actions of gap junctional blockers in an in vitro seizure model. J. Neurophys. 88 (2002) 1893-1902
10. Jefferys J.G.R. Nonsynaptic modulation of neuronal activity in the brain: electric currents and extracellular ions. Physiol. Rev. 75 (1995) 689-694
11. 2+ in rat hippocampal slices depends on gap junctional coupling. Neuroscience 105 (2001) 579-587
12. Largo C., Tombaugh G.C., Aitken P.G., Herreras O., and Somjen G.C. Heptanol but not fluoroacetate prevents the propagation of spreading depression in rat hippocampal slices. J. Neurophysiol. 77 (1997) 9-16
13. Marangoz C., and Bagirici F. Effect of l-arginine on penicillin-induced epileptiform activity in rats. Jpn. J. Pharmacol. 86 (2001) 297-301
14. Margineanu D.G., and Klitgaard H. Can gap-junction blockade preferentially inhibit neuronal hypersynchrony vs. excitability?. Neuropharmacology 41 (2001) 377-383
15. McDonald P.J., Pelletier M.R., and Carlen P.L. Putative gap junctional blockers, but not conventional antiepileptics block epileptiform discharges in piriform cortex. Soc. Neurosci. Abstr. 23 (1997) 2425
16. McLarnon J.G., Wong J.H.P., Sawyer D., and Baimbridge K.G. The actions of intermediate and long-chain n-alkanols on unitary NMDA currents in hippocampal neurons. Can. J. Physiol. Pharma. 69 (1991) 1422-1427
17. Monmaur P., Frankel-Kohn L., Sharif A., Gratio V., and M'Harzi M. Pharmacological manipulation of hippocampal nitric oxide synthesis affects the power of theta recorded from the dorsal hippocampus of urethane anesthetized rat. Brain Res. 787 (1998) 165-170
18. Nagy J.I., Yamamoto T., Sawchuk M.A., Nance D.M., and Hertzberg E.L. Quantitative immunohistochemical and biochemical correlates of connexin43 localization in rat brain. Glia 5 (1992) 1-9
19. Naus C.C., Bechberger J.F., Caveney S., and Wilson J.X. Expression of gap junction genes in astrocytes and C6 glioma cells. Neurosci. Lett. 126 (1991) 33-36
20. Naus C.C., Bechberger J.F., and Paul D.L. Gap junction gene expression in human seizure disorder. Exp. Neurol. 111 (1991) 198-203
21. Nayak A., Roy R.J., and Sharma A. Time-frequency spectral representation of the EEG as an aid in the detection of depth of anesthesia. Ann. Biomed. Eng. 22 (1994) 501-513
22. Patel S., Meldrum B.S., and Fine A. Susceptibility to pilocarpine induced seizures in rats increases with age. Behav. Brain Res. 31 (1988) 165-167
23. Paxinos G., and Watson C. The Rat Brain in the Stereotaxic Coordinates (1982), Academic Press, Sydney, New York, London
24. Pelletier M.R., and Carlen P.L. Repeated tetanic stimulation in piriform cortex in vitro: epileptogenesis and pharmacology. J. Neurophysiol. 76 (1996) 4069-4079
25. Perez-Velazquez J.L., Valiante T.A., and Carlen P.L. Modulation of gap junctional mechanisms during calcium-free induced field burst activity: a possible role for electrotonic coupling in epileptogenesis. J. Neurosci. 14 (1994) 4308-4317
26. Rayport S.G., and Kandel E.R. Epileptogenic agents enhance transmission at an identified weak electrical synapse in aplysia. Science 213 (1981) 462-464
27. Ross F.M., Gwyn P., Spanswick D., and Davies S.N. Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices. Neuroscience 100 (2000) 789-796
28. Samoilova M., Li J., Pelletier M.R., Wentlandt K., Adamchik Y., Naus C.C., and Carlen P.L. Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression. J. Neurochem. 86 (2003) 687-699
29. Shinohara K., Hiruma H., Funabashi T., and Kimura F. GABAergic modulation of gap junction communication in slice cultures of the rat suprachiasmatic nucleus. Neuroscience 96 (2000) 591-596
30. Szente M., Gajda Z., Said Ali K., and Hermesz E. Involvement of electrical coupling in the in vivo ictal epileptiform activity induced by 4-aminopyridine in the neocortex. Neuroscience 115 (2002) 1067-1078
31. Traub R.D., Bibbig A., Piechotta A., Draguhn A., and Schmitz D. Synaptic and non-synaptic contributions to giant IPSPs and ectopic spikes induced by 4-aminopyridine in the hippocampus in vitro. J. Neurophys. 85 (2001) 1246-1256
32. Traub R.D., Draguhn A., Whittington M.A., Baldewag T., Bibbig A., Buhl E.H., and Schmitz D. Axonal gap junctions between principal neurons: a novel source of network oscillations and perhaps epileptogenesis. Rev. Neurosci. 13 (2002) 1-30
33. Vaquera J., Oya S., Manrique M., Perez Lozano A., and Bravo G. Cytological alterations in alumina cream experimental epilepsy. Acta Neurochir. 42 (1978) 235-243
34. Walden J., Straub H., and Speckmann E.J. Epileptogenesis: contribution of calcium ions and antiepileptic calcium antagonists. Acta Neurol. Scand. 140 (1992) 41-46