메뉴 건너뛰기




Volumn 11, Issue 2, 2010, Pages 87-99

Astroglial networks: A step further in neuroglial and gliovascular interactions

Author keywords

[No Author keywords available]

Indexed keywords

GAP JUNCTION PROTEIN; GLUCOSE; GLUTAMIC ACID;

EID: 75649138386     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn2757     Document Type: Review
Times cited : (626)

References (149)
  • 1
    • 0004145862 scopus 로고
    • eds Kuffler, D. & Nicholls, J. G. Sinauer, Sunderland
    • Kuffler, D. & Nicholls, J. G. in From Neuron to Brain (eds Kuffler, D. & Nicholls, J. G.) 273 (Sinauer, Sunderland, 1977).
    • (1977) From Neuron to Brain , vol.273
    • Kuffler, D.1    Nicholls, J.G.2
  • 2
    • 0000770377 scopus 로고
    • eds Fedoroff, S. & Vernadakis, A. Academic Press, New York
    • Mugnaini, E. in Astrocytes (eds Fedoroff, S. & Vernadakis, A.) 329-371 (Academic Press, New York, 1986).
    • (1986) Astrocytes , pp. 329-371
    • Mugnaini, E.1
  • 3
    • 15944387795 scopus 로고    scopus 로고
    • Emerging complexities in identity and function of glial connexins
    • Theis, M., Sohl, G., Eiberger, J. & Willecke, K. Emerging complexities in identity and function of glial connexins. Trends Neurosci. 28, 188-195 (2005).
    • (2005) Trends Neurosci. , vol.28 , pp. 188-195
    • Theis, M.1    Sohl, G.2    Eiberger, J.3    Willecke, K.4
  • 4
    • 70449242819 scopus 로고
    • Transmission at the giant motor synapses of the crayfish
    • Furshpan, E. J. & Potter, D. D. Transmission at the giant motor synapses of the crayfish. J. Physiol. 145, 289-325 (1959).
    • (1959) J. Physiol. , vol.145 , pp. 289-325
    • Furshpan, E.J.1    Potter, D.D.2
  • 5
    • 0013924555 scopus 로고
    • Physiological properties of glial cells in the central nervous system of amphibia
    • Kuffler, S. W., Nicholls, J. G. & Orkand, R. K. Physiological properties of glial cells in the central nervous system of amphibia. J. Neurophysiol. 29, 768-787 (1966).
    • (1966) J. Neurophysiol. , vol.29 , pp. 768-787
    • Kuffler, S.W.1    Nicholls, J.G.2    Orkand, R.K.3
  • 6
    • 0024802648 scopus 로고
    • Differential expression of three gap junction proteins in developing and mature brain tissues
    • Dermietzel, R. et al. Differential expression of three gap junction proteins in developing and mature brain tissues. Proc. Natl Acad. Sci. USA 86, 10148-10152 (1989).
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 10148-10152
    • Dermietzel, R.1
  • 7
    • 0025963272 scopus 로고
    • Gap junctions: New tools, new answers, new questions
    • Bennett, M. V. et al. Gap junctions: new tools, new answers, new questions. Neuron 6, 305-320 (1991).
    • (1991) Neuron , vol.6 , pp. 305-320
    • Bennett, M.V.1
  • 8
    • 0035869546 scopus 로고    scopus 로고
    • Cell-specific expression of connexins and evidence of restricted gap junctional coupling between glial cells and between neurons
    • Rash, J. E., Yasumura, T., Dudek, F. E. & Nagy, J. I. Cell-specific expression of connexins and evidence of restricted gap junctional coupling between glial cells and between neurons. J. Neurosci. 21, 1983-2000 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 1983-2000
    • Rash, J.E.1    Yasumura, T.2    Dudek, F.E.3    Nagy, J.I.4
  • 9
    • 0032171494 scopus 로고    scopus 로고
    • Visualization and functional blocking of gap junction hemichannels (connexons) with antibodies against external loop domains in astrocytes
    • Hofer, A. & Dermietzel, R. Visualization and functional blocking of gap junction hemichannels (connexons) with antibodies against external loop domains in astrocytes. Glia 24, 141-154 (1998).
    • (1998) Glia , vol.24 , pp. 141-154
    • Hofer, A.1    Dermietzel, R.2
  • 10
    • 0037039391 scopus 로고    scopus 로고
    • Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture
    • Contreras, J. E. et al. Metabolic inhibition induces opening of unapposed connexin 43 gap junction hemichannels and reduces gap junctional communication in cortical astrocytes in culture. Proc. Natl Acad. Sci. USA 99, 495-500 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 495-500
    • Contreras, J.E.1
  • 11
    • 0242380301 scopus 로고    scopus 로고
    • New roles for astrocytes: Gap junction hemichannels have something to communicate
    • Bennett, M. V., Contreras, J. E., Bukauskas, F. F. & Saez, J. C. New roles for astrocytes: gap junction hemichannels have something to communicate. Trends Neurosci. 26, 610-617 (2003).
    • (2003) Trends Neurosci. , vol.26 , pp. 610-617
    • Bennett, M.V.1    Contreras, J.E.2    Bukauskas, F.F.3    Saez, J.C.4
  • 12
    • 58149100746 scopus 로고    scopus 로고
    • Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration
    • Orellana, J. A. et al. Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration. Antioxid. Redox Signal. 11, 369-399 (2009).
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 369-399
    • Orellana, J.A.1
  • 13
    • 42649102649 scopus 로고    scopus 로고
    • Connexin and pannexin mediated cell-cell communication
    • Scemes, E., Suadicani, S. O., Dahl, G. & Spray, D. C. Connexin and pannexin mediated cell-cell communication. Neuron Glia Biol. 3, 199-208 (2007).
    • (2007) Neuron Glia Biol. , vol.3 , pp. 199-208
    • Scemes, E.1    Suadicani, S.O.2    Dahl, G.3    Spray, D.C.4
  • 14
    • 0034464890 scopus 로고    scopus 로고
    • Connexins and information transfer through glia
    • Bruzzone, R. & Giaume, C. Connexins and information transfer through glia. Adv. Exp. Med. Biol. 468, 321-337 (1999).
    • (1999) Adv. Exp. Med. Biol. , vol.468 , pp. 321-337
    • Bruzzone, R.1    Giaume, C.2
  • 15
    • 0026091649 scopus 로고
    • Gap junctions between cultured astrocytes: Immunocytochemical, molecular, and electrophysiological analysis
    • Dermietzel, R., Hertberg, E. L., Kessler, J. A. & Spray, D. C. Gap junctions between cultured astrocytes: immunocytochemical, molecular, and electrophysiological analysis. J. Neurosci. 11, 1421-1432 (1991).
    • (1991) J. Neurosci. , vol.11 , pp. 1421-1432
    • Dermietzel, R.1    Hertberg, E.L.2    Kessler, J.A.3    Spray, D.C.4
  • 16
    • 0026020817 scopus 로고
    • Gap junctions in cultured astrocytes: Single-channel currents and characterization of channel-forming protein
    • Giaume, C. et al. Gap junctions in cultured astrocytes: single-channel currents and characterization of channel-forming protein. Neuron 6, 133-143 (1991).
    • (1991) Neuron , vol.6 , pp. 133-143
    • Giaume, C.1
  • 17
    • 0344528803 scopus 로고    scopus 로고
    • Late onset and increasing expression of the gap junction protein connexin30 in adult murine brain and long-term cultured astrocytes
    • Kunzelmann, P. et al. Late onset and increasing expression of the gap junction protein connexin30 in adult murine brain and long-term cultured astrocytes. Glia 25, 111-119 (1999).
    • (1999) Glia , vol.25 , pp. 111-119
    • Kunzelmann, P.1
  • 18
    • 0032889958 scopus 로고    scopus 로고
    • Connexin30 in rodent, cat and human brain: Selective expression in gray matter astrocytes, co-localization with connexin43 at gap junctions and late developmental appearance
    • Nagy, J. I., Patel, D., Ochalski, P. A. & Stelmack, G. L. Connexin30 in rodent, cat and human brain: selective expression in gray matter astrocytes, co-localization with connexin43 at gap junctions and late developmental appearance. Neuroscience 88, 447-468 (1999).
    • (1999) Neuroscience , vol.88 , pp. 447-468
    • Nagy, J.I.1    Patel, D.2    Ochalski, P.A.3    Stelmack, G.L.4
  • 19
    • 0034067910 scopus 로고    scopus 로고
    • Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS
    • Nagy, J. I. & Rash, J. E. Connexins and gap junctions of astrocytes and oligodendrocytes in the CNS. Brain Res. Brain Res. Rev. 32, 29-44 (2000).
    • (2000) Brain Res. Brain Res. Rev. , vol.32 , pp. 29-44
    • Nagy, J.I.1    Rash, J.E.2
  • 20
    • 1542269735 scopus 로고    scopus 로고
    • Endothelins regulate astrocyte gap junctions in rat hippocampal slices
    • Blomstrand, F. et al. Endothelins regulate astrocyte gap junctions in rat hippocampal slices. Eur. J. Neurosci. 19, 1005-1015 (2004).
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1005-1015
    • Blomstrand, F.1
  • 21
    • 33745003688 scopus 로고    scopus 로고
    • The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus
    • Wallraff, A. et al. The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus. J. Neurosci. 26, 5438-5447 (2006).
    • (2006) J. Neurosci. , vol.26 , pp. 5438-5447
    • Wallraff, A.1
  • 22
    • 57349185900 scopus 로고    scopus 로고
    • Astroglial metabolic networks sustain hippocampal synaptic transmission
    • Rouach, N., Koulakoff, A., Abudara, V., Willecke, K. & Giaume, C. Astroglial metabolic networks sustain hippocampal synaptic transmission. Science 322, 1551-1555 (2008).
    • (2008) Science , vol.322 , pp. 1551-1555
    • Rouach, N.1    Koulakoff, A.2    Abudara, V.3    Willecke, K.4    Giaume, C.5
  • 23
    • 34548186903 scopus 로고    scopus 로고
    • Gap junction adhesion is necessary for radial migration in the neocortex
    • Elias, L. A., Wang, D. D. & Kriegstein, A. R. Gap junction adhesion is necessary for radial migration in the neocortex. Nature 448, 901-907 (2007).
    • (2007) Nature , vol.448 , pp. 901-907
    • Elias, L.A.1    Wang, D.D.2    Kriegstein, A.R.3
  • 24
    • 37349056508 scopus 로고    scopus 로고
    • Modulation of astrocyte P2Y1 receptors by the carboxyl terminal domain of the gap junction protein Cx43
    • Scemes, E. Modulation of astrocyte P2Y1 receptors by the carboxyl terminal domain of the gap junction protein Cx43. Glia 56, 145-153 (2008).
    • (2008) Glia , vol.56 , pp. 145-153
    • Scemes, E.1
  • 26
    • 75649100810 scopus 로고    scopus 로고
    • They are often located close to synapses and can occur between two processes of a single cell (reflexive gap junctions)
    • Report of two important properties of gap junctions in astrocytes. They are often located close to synapses and can occur between two processes of a single cell (reflexive gap junctions).
    • Report of Two Important Properties of Gap Junctions in Astrocytes
  • 27
    • 0036139877 scopus 로고    scopus 로고
    • Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains
    • Bushong, E. A., Martone, M. E., Jones, Y. Z. & Ellisman, M. H. Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. J. Neurosci. 22, 183-192 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 183-192
    • Bushong, E.A.1    Martone, M.E.2    Jones, Y.Z.3    Ellisman, M.H.4
  • 28
    • 34250317399 scopus 로고    scopus 로고
    • Synaptic islands defined by the territory of a single astrocyte
    • Halassa, M. M., Fellin, T., Takano, H., Dong, J. H. & Haydon, P. G. Synaptic islands defined by the territory of a single astrocyte. J. Neurosci. 27, 6473-6477 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 6473-6477
    • Halassa, M.M.1    Fellin, T.2    Takano, H.3    Dong, J.H.4    Haydon, P.G.5
  • 29
    • 0037008429 scopus 로고    scopus 로고
    • Structural and quantitative analysis of astrocytes in the mouse hippocampus
    • Ogata, K. & Kosaka, T. Structural and quantitative analysis of astrocytes in the mouse hippocampus. Neuroscience 113, 221-233 (2002).
    • (2002) Neuroscience , vol.113 , pp. 221-233
    • Ogata, K.1    Kosaka, T.2
  • 30
    • 0027959692 scopus 로고
    • Astrocytic dye coupling in rat hippocampus: Topography, developmental onset, and modulation by protein kinase C
    • Konietzko, U. & Muller, C. M. Astrocytic dye coupling in rat hippocampus: topography, developmental onset, and modulation by protein kinase C. Hippocampus 4, 297-306 (1994).
    • (1994) Hippocampus , vol.4 , pp. 297-306
    • Konietzko, U.1    Muller, C.M.2
  • 31
    • 0032526704 scopus 로고    scopus 로고
    • Functional specialization and topographic segregation of hippocampal astrocytes
    • D'Ambrosio, R., Wenzel, J., Schwartzkroin, P. A., McKhann, G. M. & Janigro, D. Functional specialization and topographic segregation of hippocampal astrocytes. J. Neurosci. 18, 4425-4438 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 4425-4438
    • D'Ambrosio, R.1    Wenzel, J.2    Schwartzkroin, P.A.3    McKhann, G.M.4    Janigro, D.5
  • 32
    • 45549083671 scopus 로고    scopus 로고
    • Gap junction-mediated astrocytic networks in the mouse barrel cortex
    • Houades, V., Koulakoff, A., Ezan, P., Seif, I. & Giaume, C. Gap junction-mediated astrocytic networks in the mouse barrel cortex. J. Neurosci. 28, 5207-5217 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 5207-5217
    • Houades, V.1    Koulakoff, A.2    Ezan, P.3    Seif, I.4    Giaume, C.5
  • 33
    • 35448976605 scopus 로고    scopus 로고
    • 14C] glucose metabolite trafficking
    • Ball, K. K., Gandhi, G. K., Thrash, J., Cruz, N. F. & Dienel, G. A. Astrocytic connexin distributions and rapid, extensive dye transfer via gap junctions in the inferior colliculus: implications for [14C]glucose metabolite trafficking. J. Neurosci. Res. 85, 3267-3283 (2007).
    • (2007) J. Neurosci. Res. , vol.85 , pp. 3267-3283
    • Ball, K.K.1    Gandhi, G.K.2    Thrash, J.3    Cruz, N.F.4    Dienel, G.A.5
  • 34
    • 42149172269 scopus 로고    scopus 로고
    • Electrophysiological properties and gap junction coupling of striatal astrocytes
    • Adermark, L. & Lovinger, D. M. Electrophysiological properties and gap junction coupling of striatal astrocytes. Neurochem. Int. 52, 1365-1372 (2008).
    • (2008) Neurochem. Int. , vol.52 , pp. 1365-1372
    • Adermark, L.1    Lovinger, D.M.2
  • 35
    • 0033364178 scopus 로고    scopus 로고
    • Microdomains for neuron-glia interaction: Parallel fiber signaling to Bergmann glial cells
    • Grosche, J. et al. Microdomains for neuron-glia interaction: parallel fiber signaling to Bergmann glial cells. Nature Neurosci. 2, 139-143 (1999).
    • (1999) Nature Neurosci. , vol.2 , pp. 139-143
    • Grosche, J.1
  • 36
    • 0026683777 scopus 로고
    • Postnatal development of dye-coupling among astrocytes in rat visual cortex
    • Binmoller, F. J. & Muller, C. M. Postnatal development of dye-coupling among astrocytes in rat visual cortex. Glia 6, 127-137 (1992).
    • (1992) Glia , vol.6 , pp. 127-137
    • Binmoller, F.J.1    Muller, C.M.2
  • 37
    • 33748549627 scopus 로고    scopus 로고
    • Development of gap junctions in hippocampal astrocytes: Evidence that whole cell electrophysiological phenotype is an intrinsic property of the individual cell
    • Schools, G. P., Zhou, M. & Kimelberg, H. K. Development of gap junctions in hippocampal astrocytes: evidence that whole cell electrophysiological phenotype is an intrinsic property of the individual cell. J. Neurophysiol. 96, 1383-1392 (2006).
    • (2006) J. Neurophysiol. , vol.96 , pp. 1383-1392
    • Schools, G.P.1    Zhou, M.2    Kimelberg, H.K.3
  • 38
    • 0037059884 scopus 로고    scopus 로고
    • Connexin expression in homotypic and heterotypic cell coupling in the developing cerebral cortex
    • Bittman, K., Becker, D. L., Cicirata, F. & Parnavelas, J. G. Connexin expression in homotypic and heterotypic cell coupling in the developing cerebral cortex. J. Comp. Neurol. 443, 201-212 (2002).
    • (2002) J. Comp. Neurol. , vol.443 , pp. 201-212
    • Bittman, K.1    Becker, D.L.2    Cicirata, F.3    Parnavelas, J.G.4
  • 40
    • 10644284880 scopus 로고    scopus 로고
    • Electrical synapses between Bergmann glia cells and Purkinje neurones in rat cerebellar slices
    • Pakhotin, P. & Verkhratsky, A. Electrical synapses between Bergmann glia cells and Purkinje neurones in rat cerebellar slices. Mol. Cell. Neurosci. 28, 79-84 (2005).
    • (2005) Mol. Cell. Neurosci. , vol.28 , pp. 79-84
    • Pakhotin, P.1    Verkhratsky, A.2
  • 41
    • 0028959939 scopus 로고
    • Homotypic and heterotypic coupling mediated by gap junctions during glial cell differentiation in vitro
    • Venance, L. et al. Homotypic and heterotypic coupling mediated by gap junctions during glial cell differentiation in vitro. Eur. J. Neurosci. 7, 451-461 (1995).
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 451-461
    • Venance, L.1
  • 42
    • 75649151437 scopus 로고    scopus 로고
    • Gap junction coupling among oligodendrocytes in mouse corpus callsoum is largely promoted by connexin47
    • Maglione, T. et al. Gap junction coupling among oligodendrocytes in mouse corpus callsoum is largely promoted by connexin47. Glia 57 (Suppl. 13), 178 (2009).
    • (2009) Glia , vol.57 , Issue.SUPPL. 13 , pp. 178
    • Maglione, T.1
  • 43
    • 67449119205 scopus 로고    scopus 로고
    • Deletion of astrocyte connexins 43 and 30 leads to a dysmyelinating phenotype and hippocampal CA1 vacuolation
    • Lutz, S. E. et al. Deletion of astrocyte connexins 43 and 30 leads to a dysmyelinating phenotype and hippocampal CA1 vacuolation. J. Neurosci. 29, 7743-7752 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 7743-7752
    • Lutz, S.E.1
  • 44
    • 32644470069 scopus 로고    scopus 로고
    • Shapes of astrocyte networks in the juvenile brain
    • Houades, V. et al. Shapes of astrocyte networks in the juvenile brain. Neuron Glia Biol. 2, 3-14 (2006).
    • (2006) Neuron Glia Biol. , vol.2 , pp. 3-14
    • Houades, V.1
  • 45
    • 75649091777 scopus 로고    scopus 로고
    • Two astroglial networks are differentially regulated by neuronal activity in the olfactory glomerular layer
    • Roux, L. & Giaume, C. Two astroglial networks are differentially regulated by neuronal activity in the olfactory glomerular layer. Glia 57 (Suppl. 13), 57 (2009).
    • (2009) Glia , vol.57 , Issue.SUPPL. 13 , pp. 57
    • Roux, L.1    Giaume, C.2
  • 46
    • 77952422253 scopus 로고    scopus 로고
    • Heterogeneity in astrocyte morphology and physiology
    • 11 Dec doi:10.1016/j.brainresrev.2009.12.001
    • Matyash, V. & Kettenmann, H. Heterogeneity in astrocyte morphology and physiology. Brain Res. Rev. 11 Dec 2009 (doi:10.1016/j.brainresrev.2009.12. 001).
    • (2009) Brain Res. Rev.
    • Matyash, V.1    Kettenmann, H.2
  • 47
    • 0035906514 scopus 로고    scopus 로고
    • Expression and function of astrocytic gap junctions in aging
    • Cotrina, M. L., Gao, Q., Lin, J. H. & Nedergaard, M. Expression and function of astrocytic gap junctions in aging. Brain Res. 901, 55-61 (2001).
    • (2001) Brain Res. , vol.901 , pp. 55-61
    • Cotrina, M.L.1    Gao, Q.2    Lin, J.H.3    Nedergaard, M.4
  • 48
    • 70349147807 scopus 로고    scopus 로고
    • Astrocyte function is modified by alzheimer's disease-like pathology in aged mice
    • Peters, O. et al. Astrocyte function is modified by alzheimer's disease-like pathology in aged mice. J. Alzheimers Dis. 18, 177-189 (2009).
    • (2009) J. Alzheimers Dis. , vol.18 , pp. 177-189
    • Peters, O.1
  • 49
    • 0026521013 scopus 로고
    • Differential anatomical and cellular patterns of connexin43 expression during postnatal development of rat brain
    • Yamamoto, T., Vukelic, J., Hertzberg, E. L. & Nagy, J. I. Differential anatomical and cellular patterns of connexin43 expression during postnatal development of rat brain. Brain Res. Dev. Brain Res. 66, 165-180 (1992).
    • (1992) Brain Res. Dev. Brain Res. , vol.66 , pp. 165-180
    • Yamamoto, T.1    Vukelic, J.2    Hertzberg, E.L.3    Nagy, J.I.4
  • 50
    • 0035839175 scopus 로고    scopus 로고
    • Regional variation in brain capillary density and vascular response to ischemia
    • Cavaglia, M. et al. Regional variation in brain capillary density and vascular response to ischemia. Brain Res. 910, 81-93 (2001).
    • (2001) Brain Res. , vol.910 , pp. 81-93
    • Cavaglia, M.1
  • 51
    • 0017850829 scopus 로고
    • Transmission of hormonal stimulation by cell-to-cell communication
    • Lawrence, T. S., Beers, W. H. & Gilula, N. B. Transmission of hormonal stimulation by cell-to-cell communication. Nature 272, 501-506 (1978).
    • (1978) Nature , vol.272 , pp. 501-506
    • Lawrence, T.S.1    Beers, W.H.2    Gilula, N.B.3
  • 52
    • 33750447312 scopus 로고    scopus 로고
    • Glucose metabolism and proliferation in glia: Role of astrocytic gap junctions
    • Tabernero, A., Medina, J. M. & Giaume, C. Glucose metabolism and proliferation in glia: role of astrocytic gap junctions. J. Neurochem. 99, 1049-1061 (2006).
    • (2006) J. Neurochem. , vol.99 , pp. 1049-1061
    • Tabernero, A.1    Medina, J.M.2    Giaume, C.3
  • 53
    • 34249082403 scopus 로고    scopus 로고
    • Connexin channel permeability to cytoplasmic molecules
    • Harris, A. L. Connexin channel permeability to cytoplasmic molecules. Prog. Biophys. Mol. Biol. 94, 120-143 (2007).
    • (2007) Prog. Biophys. Mol. Biol. , vol.94 , pp. 120-143
    • Harris, A.L.1
  • 54
    • 34548786265 scopus 로고    scopus 로고
    • Human connexin26 and connexin30 form functional heteromeric and heterotypic channels
    • Yum, S. W. et al. Human connexin26 and connexin30 form functional heteromeric and heterotypic channels. Am. J. Physiol. Cell Physiol. 293, C1032-C1048 (2007).
    • (2007) Am. J. Physiol. Cell Physiol. , vol.293
    • Yum, S.W.1
  • 55
    • 0034998680 scopus 로고    scopus 로고
    • Intracellular domains of mouse connexin26 and-30 affect diffusional and electrical properties of gap junction channels
    • Manthey, D. et al. Intracellular domains of mouse connexin26 and-30 affect diffusional and electrical properties of gap junction channels. J. Membr. Biol. 181, 137-148 (2001).
    • (2001) J. Membr. Biol. , vol.181 , pp. 137-148
    • Manthey, D.1
  • 56
    • 38449107562 scopus 로고    scopus 로고
    • Two distinct heterotypic channels mediate gap junction coupling between astrocyte and oligodendrocyte connexins
    • Orthmann-Murphy, J. L., Freidin, M., Fischer, E., Scherer, S. S. & Abrams, C. K. Two distinct heterotypic channels mediate gap junction coupling between astrocyte and oligodendrocyte connexins. J. Neurosci. 27, 13949-13957 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 13949-13957
    • Orthmann-Murphy, J.L.1    Freidin, M.2    Fischer, E.3    Scherer, S.S.4    Abrams, C.K.5
  • 57
    • 34249050091 scopus 로고    scopus 로고
    • Molecular basis of voltage dependence of connexin channels: An integrative appraisal
    • Gonzalez, D., Gomez-Hernandez, J. M. & Barrio, L. C. Molecular basis of voltage dependence of connexin channels: an integrative appraisal. Prog. Biophys. Mol. Biol. 94, 66-106 (2007).
    • (2007) Prog. Biophys. Mol. Biol. , vol.94 , pp. 66-106
    • Gonzalez, D.1    Gomez-Hernandez, J.M.2    Barrio, L.C.3
  • 58
    • 0032054926 scopus 로고    scopus 로고
    • Astrocytic gap junctions remain open during ischemic conditions
    • Cotrina, M. L. et al. Astrocytic gap junctions remain open during ischemic conditions. J. Neurosci. 18, 2520-2537 (1998).
    • (1998) J. Neurosci. , vol.18 , pp. 2520-2537
    • Cotrina, M.L.1
  • 59
    • 33744999630 scopus 로고    scopus 로고
    • GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression
    • Serrano, A., Haddjeri, N., Lacaille, J. C. & Robitaille, R. GABAergic network activation of glial cells underlies hippocampal heterosynaptic depression. J. Neurosci. 26, 5370-5382 (2006).
    • (2006) J. Neurosci. , vol.26 , pp. 5370-5382
    • Serrano, A.1    Haddjeri, N.2    Lacaille, J.C.3    Robitaille, R.4
  • 60
    • 28044436908 scopus 로고    scopus 로고
    • Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons
    • Kang, N., Xu, J., Xu, Q., Nedergaard, M. & Kang, J. Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons. J. Neurophysiol. 94, 4121-4130 (2005).
    • (2005) J. Neurophysiol. , vol.94 , pp. 4121-4130
    • Kang, N.1    Xu, J.2    Xu, Q.3    Nedergaard, M.4    Kang, J.5
  • 61
    • 27644502287 scopus 로고    scopus 로고
    • Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions
    • Valiunas, V. et al. Connexin-specific cell-to-cell transfer of short interfering RNA by gap junctions. J. Physiol. 568, 459-468 (2005).
    • (2005) J. Physiol. , vol.568 , pp. 459-468
    • Valiunas, V.1
  • 62
    • 0034717542 scopus 로고    scopus 로고
    • Activity-dependent neuronal control of gap-junctional communication in astrocytes
    • Rouach, N., Glowinski, J. & Giaume, C. Activity-dependent neuronal control of gap-junctional communication in astrocytes. J. Cell Biol. 149, 1513-1526 (2000).
    • (2000) J. Cell Biol. , vol.149 , pp. 1513-1526
    • Rouach, N.1    Glowinski, J.2    Giaume, C.3
  • 63
    • 0021961190 scopus 로고
    • Cultured astrocytes form a syncytium after maturation
    • Fischer, G. & Kettenmann, H. Cultured astrocytes form a syncytium after maturation. Exp. Cell Res. 159, 273-279 (1985).
    • (1985) Exp. Cell Res. , vol.159 , pp. 273-279
    • Fischer, G.1    Kettenmann, H.2
  • 64
    • 0030106251 scopus 로고    scopus 로고
    • Nerve impulses increase glial intercellular permeability
    • Marrero, H. & Orkand, R. K. Nerve impulses increase glial intercellular permeability. Glia 16, 285-289 (1996).
    • (1996) Glia , vol.16 , pp. 285-289
    • Marrero, H.1    Orkand, R.K.2
  • 66
    • 0028079648 scopus 로고
    • + concentration
    • Enkvist, M. O. & McCarthy, K. D. Astroglial gap junction communication is increased by treatment with either glutamate or high K+ concentration. J. Neurochem. 62, 489-495 (1994).
    • (1994) J. Neurochem. , vol.62 , pp. 489-495
    • Enkvist, M.O.1    McCarthy, K.D.2
  • 67
    • 0035449909 scopus 로고    scopus 로고
    • +-induced increase in Gap junctional communication between mouse spinal cord astrocytes
    • De Pina-Benabou, M. H., Srinivas, M., Spray, D. C. & Scemes, E. Calmodulin kinase pathway mediates the K+-induced increase in Gap junctional communication between mouse spinal cord astrocytes. J. Neurosci. 21, 6635-6643 (2001).
    • (2001) J. Neurosci. , vol.21 , pp. 6635-6643
    • De Pina-Benabou, M.H.1    Srinivas, M.2    Spray, D.C.3    Scemes, E.4
  • 68
    • 0037154181 scopus 로고    scopus 로고
    • Costimulation of N-methyl-d-aspartate and muscarinic neuronal receptors modulates gap junctional communication in striatal astrocytes
    • Rouach, N., Tence, M., Glowinski, J. & Giaume, C. Costimulation of N-methyl-d-aspartate and muscarinic neuronal receptors modulates gap junctional communication in striatal astrocytes. Proc. Natl Acad. Sci. USA 99, 1023-1028 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 1023-1028
    • Rouach, N.1    Tence, M.2    Glowinski, J.3    Giaume, C.4
  • 69
    • 61549119185 scopus 로고    scopus 로고
    • Differential NMDA-dependent activation of glial cells in mouse hippocampus
    • Serrano, A., Robitaille, R. & Lacaille, J. C. Differential NMDA-dependent activation of glial cells in mouse hippocampus. Glia 56, 1648-1663 (2008).
    • (2008) Glia , vol.56 , pp. 1648-1663
    • Serrano, A.1    Robitaille, R.2    Lacaille, J.C.3
  • 70
    • 0030219458 scopus 로고    scopus 로고
    • Electrical coupling among Bergmann glial cells and its modulation by glutamate receptor activation
    • Muller, T., Moller, T., Neuhaus, J. & Kettenmann, H. Electrical coupling among Bergmann glial cells and its modulation by glutamate receptor activation. Glia 17, 274-284 (1996).
    • (1996) Glia , vol.17 , pp. 274-284
    • Muller, T.1    Moller, T.2    Neuhaus, J.3    Kettenmann, H.4
  • 71
    • 4344659272 scopus 로고    scopus 로고
    • Distinct types of astroglial cells in the hippocampus differ in gap junction coupling
    • Wallraff, A., Odermatt, B., Willecke, K. & Steinhauser, C. Distinct types of astroglial cells in the hippocampus differ in gap junction coupling. Glia 48, 36-43 (2004).
    • (2004) Glia , vol.48 , pp. 36-43
    • Wallraff, A.1    Odermatt, B.2    Willecke, K.3    Steinhauser, C.4
  • 72
    • 0037335461 scopus 로고    scopus 로고
    • Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus
    • Matthias, K. et al. Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J. Neurosci. 23, 1750-1758 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 1750-1758
    • Matthias, K.1
  • 73
    • 33745873475 scopus 로고    scopus 로고
    • Astrocyte control of synaptic transmission and neurovascular coupling
    • Haydon, P. G. & Carmignoto, G. Astrocyte control of synaptic transmission and neurovascular coupling. Physiol. Rev. 86, 1009-1031 (2006).
    • (2006) Physiol. Rev. , vol.86 , pp. 1009-1031
    • Haydon, P.G.1    Carmignoto, G.2
  • 74
    • 68049143450 scopus 로고    scopus 로고
    • Tripartite synapses: Astrocytes process and control synaptic information
    • Perea, G., Navarrete, M. & Araque, A. Tripartite synapses: astrocytes process and control synaptic information. Trends Neurosci. 32, 421-431 (2009).
    • (2009) Trends Neurosci. , vol.32 , pp. 421-431
    • Perea, G.1    Navarrete, M.2    Araque, A.3
  • 75
    • 2542501505 scopus 로고    scopus 로고
    • Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate
    • Bezzi, P. et al. Astrocytes contain a vesicular compartment that is competent for regulated exocytosis of glutamate. Nature Neurosci. 7, 613-620 (2004).
    • (2004) Nature Neurosci. , vol.7 , pp. 613-620
    • Bezzi, P.1
  • 76
    • 11144358154 scopus 로고    scopus 로고
    • Fusion-related release of glutamate from astrocytes
    • Zhang, Q. et al. Fusion-related release of glutamate from astrocytes. J. Biol. Chem. 279, 12724-12733 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 12724-12733
    • Zhang, Q.1
  • 77
    • 1642355796 scopus 로고    scopus 로고
    • Vesicular glutamate transporter-dependent glutamate release from astrocytes
    • Montana, V., Ni, Y., Sunjara, V., Hua, X. & Parpura, V. Vesicular glutamate transporter-dependent glutamate release from astrocytes. J. Neurosci. 24, 2633-2642 (2004).
    • (2004) J. Neurosci. , vol.24 , pp. 2633-2642
    • Montana, V.1    Ni, Y.2    Sunjara, V.3    Hua, X.4    Parpura, V.5
  • 78
    • 17244382523 scopus 로고    scopus 로고
    • Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine
    • Mothet, J. P. et al. Glutamate receptor activation triggers a calcium-dependent and SNARE protein-dependent release of the gliotransmitter D-serine. Proc. Natl Acad. Sci. USA 102, 5606-5611 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 5606-5611
    • Mothet, J.P.1
  • 79
    • 33847183442 scopus 로고    scopus 로고
    • Glutamate exocytosis from astrocytes controls synaptic strength
    • Jourdain, P. et al. Glutamate exocytosis from astrocytes controls synaptic strength. Nature Neurosci. 10, 331-339 (2007).
    • (2007) Nature Neurosci. , vol.10 , pp. 331-339
    • Jourdain, P.1
  • 80
    • 34248545253 scopus 로고    scopus 로고
    • Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity
    • Fiacco, T. A. et al. Selective stimulation of astrocyte calcium in situ does not affect neuronal excitatory synaptic activity. Neuron 54, 611-626 (2007).
    • (2007) Neuron , vol.54 , pp. 611-626
    • Fiacco, T.A.1
  • 82
    • 44949238601 scopus 로고    scopus 로고
    • 2+ increases in hippocampal astrocytes does not affect baseline CA1 pyramidal neuron synaptic activity
    • Petravicz, J., Fiacco, T. A. & McCarthy, K. D. Loss of IP3 receptor-dependent Ca2+ increases in hippocampal astrocytes does not affect baseline CA1 pyramidal neuron synaptic activity. J. Neurosci. 28, 4967-4973 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 4967-4973
    • Petravicz, J.1    Fiacco, T.A.2    McCarthy, K.D.3
  • 83
    • 55049084760 scopus 로고    scopus 로고
    • The mystery and magic of glia: A perspective on their roles in health and disease
    • Barres, B. A. The mystery and magic of glia: a perspective on their roles in health and disease. Neuron 60, 430-440 (2008).
    • (2008) Neuron , vol.60 , pp. 430-440
    • Barres, B.A.1
  • 84
    • 0031239423 scopus 로고    scopus 로고
    • Metabolic trafficking through astrocytic gap junctions
    • Giaume, C., Tabernero, A. & Medina, J. M. Metabolic trafficking through astrocytic gap junctions. Glia 21, 114-123 (1997).
    • (1997) Glia , vol.21 , pp. 114-123
    • Giaume, C.1    Tabernero, A.2    Medina, J.M.3
  • 86
    • 33745988312 scopus 로고    scopus 로고
    • Neuron-glia metabolic coupling and plasticity
    • Magistretti, P. J. Neuron-glia metabolic coupling and plasticity. J. Exp. Biol. 209, 2304-2311 (2006).
    • (2006) J. Exp. Biol. , vol.209 , pp. 2304-2311
    • Magistretti, P.J.1
  • 87
    • 0024412810 scopus 로고
    • On the structure of nerve cells. 1898
    • Golgi, C. On the structure of nerve cells. 1898. J. Microsc. 155, 3-7 (1989).
    • (1989) J. Microsc. , vol.155 , pp. 3-7
    • Golgi, C.1
  • 88
    • 84940620788 scopus 로고
    • Regulation of astrocyte energy metabolism by neurotransmitters
    • Magistretti, P. J. et al. Regulation of astrocyte energy metabolism by neurotransmitters. Ren Physiol. Biochem. 17, 168-171 (1994).
    • (1994) Ren Physiol. Biochem. , vol.17 , pp. 168-171
    • Magistretti, P.J.1
  • 90
    • 33750368810 scopus 로고    scopus 로고
    • Astrocyte calcium waves: What they are and what they do
    • Scemes, E. & Giaume, C. Astrocyte calcium waves: what they are and what they do. Glia 54, 716-725 (2006).
    • (2006) Glia , vol.54 , pp. 716-725
    • Scemes, E.1    Giaume, C.2
  • 91
    • 33750338533 scopus 로고    scopus 로고
    • Astrocyte calcium elevations: Properties, propagation, and effects on brain signaling
    • Fiacco, T. A. & McCarthy, K. D. Astrocyte calcium elevations: properties, propagation, and effects on brain signaling. Glia 54, 676-690 (2006).
    • (2006) Glia , vol.54 , pp. 676-690
    • Fiacco, T.A.1    McCarthy, K.D.2
  • 92
    • 61349096009 scopus 로고    scopus 로고
    • Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice
    • Kuchibhotla, K. V., Lattarulo, C. R., Hyman, B. T. & Bacskai, B. J. Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice. Science 323, 1211-1215 (2009).
    • (2009) Science , vol.323 , pp. 1211-1215
    • Kuchibhotla, K.V.1    Lattarulo, C.R.2    Hyman, B.T.3    Bacskai, B.J.4
  • 93
    • 0030110740 scopus 로고    scopus 로고
    • Endothelin-1 regulates glucose utilization in cultured astrocytes by controlling intercellular communication through gap junctions
    • Tabernero, A., Giaume, C. & Medina, J. M. Endothelin-1 regulates glucose utilization in cultured astrocytes by controlling intercellular communication through gap junctions. Glia 16, 187-195 (1996).
    • (1996) Glia , vol.16 , pp. 187-195
    • Tabernero, A.1    Giaume, C.2    Medina, J.M.3
  • 94
    • 34347237157 scopus 로고    scopus 로고
    • 14C]glucose metabolite spreading and release
    • Cruz, N. F., Ball, K. K. & Dienel, G. A. Functional imaging of focal brain activation in conscious rats: impact of [14C]glucose metabolite spreading and release. J. Neurosci. Res. 85, 3254-3266 (2007).
    • (2007) J. Neurosci. Res. , vol.85 , pp. 3254-3266
    • Cruz, N.F.1    Ball, K.K.2    Dienel, G.A.3
  • 95
    • 34748868503 scopus 로고    scopus 로고
    • Neurometabolic coupling in cerebral cortex reflects synaptic more than spiking activity
    • Viswanathan, A. & Freeman, R. D. Neurometabolic coupling in cerebral cortex reflects synaptic more than spiking activity. Nature Neurosci. 10, 1308-1312 (2007).
    • (2007) Nature Neurosci. , vol.10 , pp. 1308-1312
    • Viswanathan, A.1    Freeman, R.D.2
  • 96
    • 59649119749 scopus 로고    scopus 로고
    • Odor-evoked oxygen consumption by action potential and synaptic transmission in the olfactory bulb
    • Lecoq, J. et al. Odor-evoked oxygen consumption by action potential and synaptic transmission in the olfactory bulb. J. Neurosci. 29, 1424-1433 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 1424-1433
    • Lecoq, J.1
  • 97
    • 0142027742 scopus 로고    scopus 로고
    • GABA uptake into astrocytes is not associated with significant metabolic cost: Implications for brain imaging of inhibitory transmission
    • Chatton, J. Y., Pellerin, L. & Magistretti, P. J. GABA uptake into astrocytes is not associated with significant metabolic cost: implications for brain imaging of inhibitory transmission. Proc. Natl Acad. Sci. USA 100, 12456-12461 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 12456-12461
    • Chatton, J.Y.1    Pellerin, L.2    Magistretti, P.J.3
  • 98
    • 34547797327 scopus 로고    scopus 로고
    • Astrocyte control of the cerebrovasculature
    • Gordon, G. R., Mulligan, S. J. & MacVicar, B. A. Astrocyte control of the cerebrovasculature. Glia 55, 1214-1221 (2007).
    • (2007) Glia , vol.55 , pp. 1214-1221
    • Gordon, G.R.1    Mulligan, S.J.2    MacVicar, B.A.3
  • 99
    • 61649098367 scopus 로고    scopus 로고
    • Astrocytes and the regulation of cerebral blood flow
    • Koehler, R. C., Roman, R. J. & Harder, D. R. Astrocytes and the regulation of cerebral blood flow. Trends Neurosci. 32, 160-169 (2009).
    • (2009) Trends Neurosci. , vol.32 , pp. 160-169
    • Koehler, R.C.1    Roman, R.J.2    Harder, D.R.3
  • 100
    • 4544222190 scopus 로고    scopus 로고
    • Calcium transients in astrocyte endfeet cause cerebrovascular constrictions
    • Mulligan, S. J. & MacVicar, B. A. Calcium transients in astrocyte endfeet cause cerebrovascular constrictions. Nature 431, 195-199 (2004).
    • (2004) Nature , vol.431 , pp. 195-199
    • Mulligan, S.J.1    MacVicar, B.A.2
  • 101
    • 62549132717 scopus 로고    scopus 로고
    • Radially expanding transglial calcium waves in the intact cerebellum
    • Hoogland, T. M. et al. Radially expanding transglial calcium waves in the intact cerebellum. Proc. Natl Acad. Sci. USA 106, 3496-3501 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 3496-3501
    • Hoogland, T.M.1
  • 102
    • 58749105837 scopus 로고    scopus 로고
    • Limited intravascular coupling in the rodent brainstem and retina supports a role for glia in regional blood flow
    • Kuo, I. Y., Chan-Ling, T., Wojcikiewicz, R. J. & Hill, C. E. Limited intravascular coupling in the rodent brainstem and retina supports a role for glia in regional blood flow. J. Comp. Neurol. 511, 773-787 (2008).
    • (2008) J. Comp. Neurol. , vol.511 , pp. 773-787
    • Kuo, I.Y.1    Chan-Ling, T.2    Wojcikiewicz, R.J.3    Hill, C.E.4
  • 103
    • 0030697366 scopus 로고    scopus 로고
    • Reactive astrocytes: Cellular and molecular cues to biological function
    • Ridet, J. L., Malhotra, S. K., Privat, A. & Gage, F. H. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci. 20, 570-577 (1997).
    • (1997) Trends Neurosci. , vol.20 , pp. 570-577
    • Ridet, J.L.1    Malhotra, S.K.2    Privat, A.3    Gage, F.H.4
  • 104
    • 41549146380 scopus 로고    scopus 로고
    • Loss of astrocytic domain organization in the epileptic brain
    • Oberheim, N. A. et al. Loss of astrocytic domain organization in the epileptic brain. J. Neurosci. 28, 3264-3276 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 3264-3276
    • Oberheim, N.A.1
  • 105
    • 0031841797 scopus 로고    scopus 로고
    • Immunorecognition ultrastructure and phosphorylation status of astrocytic gap junctions and connexin43 in rat brain after cerebral focal ischaemia
    • Li, W. E., Ochalski, P. A., Hertzberg, E. L. & Nagy, J. I. Immunorecognition, ultrastructure and phosphorylation status of astrocytic gap junctions and connexin43 in rat brain after cerebral focal ischaemia. Eur. J. Neurosci. 10, 2444-2463 (1998).
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 2444-2463
    • Li, W.E.1    Ochalski, P.A.2    Hertzberg, E.L.3    Nagy, J.I.4
  • 106
    • 0031548034 scopus 로고    scopus 로고
    • Connexin43 and astrocytic gap junctions in the rat spinal cord after acute compression injury
    • Theriault, E., Frankenstein, U. N., Hertzberg, E. L. & Nagy, J. I. Connexin43 and astrocytic gap junctions in the rat spinal cord after acute compression injury. J. Comp. Neurol. 382, 199-214 (1997).
    • (1997) J. Comp. Neurol. , vol.382 , pp. 199-214
    • Theriault, E.1    Frankenstein, U.N.2    Hertzberg, E.L.3    Nagy, J.I.4
  • 107
    • 0029347096 scopus 로고
    • Astrocytic gap junction removal, connexin43 redistribution, and epitope masking at excitatory amino acid lesion sites in rat brain
    • Ochalski, P. A., Sawchuk, M. A., Hertzberg, E. L. & Nagy, J. I. Astrocytic gap junction removal, connexin43 redistribution, and epitope masking at excitatory amino acid lesion sites in rat brain. Glia 14, 279-294 (1995).
    • (1995) Glia , vol.14 , pp. 279-294
    • Ochalski, P.A.1    Sawchuk, M.A.2    Hertzberg, E.L.3    Nagy, J.I.4
  • 108
    • 51349116146 scopus 로고    scopus 로고
    • Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes
    • Koulakoff, A., Ezan, P. & Giaume, C. Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes. Glia 56, 1299-1311 (2008).
    • (2008) Glia , vol.56 , pp. 1299-1311
    • Koulakoff, A.1    Ezan, P.2    Giaume, C.3
  • 109
    • 0029879282 scopus 로고    scopus 로고
    • Elevated connexin43 immunoreactivity at sites of amyloid plaques in Alzheimer's disease
    • Nagy, J. I., Li, W., Hertzberg, E. L. & Marotta, C. A. Elevated connexin43 immunoreactivity at sites of amyloid plaques in Alzheimer's disease. Brain Res. 717, 173-178 (1996).
    • (1996) Brain Res. , vol.717 , pp. 173-178
    • Nagy, J.I.1    Li, W.2    Hertzberg, E.L.3    Marotta, C.A.4
  • 110
    • 0041802936 scopus 로고    scopus 로고
    • Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: Increased gap junctional function and expression
    • Samoilova, M. et al. Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression. J. Neurochem. 86, 687-699 (2003).
    • (2003) J. Neurochem. , vol.86 , pp. 687-699
    • Samoilova, M.1
  • 111
    • 41149164595 scopus 로고    scopus 로고
    • Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures
    • Samoilova, M., Wentlandt, K., Adamchik, Y., Velumian, A. A. & Carlen, P. L. Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures. Exp. Neurol. 210, 762-775 (2008).
    • (2008) Exp. Neurol. , vol.210 , pp. 762-775
    • Samoilova, M.1    Wentlandt, K.2    Adamchik, Y.3    Velumian, A.A.4    Carlen, P.L.5
  • 112
    • 64449086356 scopus 로고    scopus 로고
    • Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex
    • Xu, L., Zeng, L. H. & Wong, M. Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex. Neurobiol. Dis. 34, 291-299 (2009).
    • (2009) Neurobiol. Dis. , vol.34 , pp. 291-299
    • Xu, L.1    Zeng, L.H.2    Wong, M.3
  • 113
    • 77952426247 scopus 로고    scopus 로고
    • Pharmacological and genetic approaches to study connexin-mediated channels in glial cells of the central nervous system
    • 4 Dec doi:10.1016/j.brainresrev.2009.11.005
    • Giaume, C. & Theis, M. Pharmacological and genetic approaches to study connexin-mediated channels in glial cells of the central nervous system. Brain Res. Rev. 4 Dec 2009 (doi:10.1016/j. brainresrev.2009.11.005).
    • (2009) Brain Res. Rev.
    • Giaume, C.1    Theis, M.2
  • 114
    • 38549168318 scopus 로고    scopus 로고
    • A central role of connexin 43 in hypoxic preconditioning
    • Lin, J. H. et al. A central role of connexin 43 in hypoxic preconditioning. J. Neurosci. 28, 681-695 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 681-695
    • Lin, J.H.1
  • 116
    • 0347126463 scopus 로고    scopus 로고
    • Neuroprotective role of astrocytic gap junctions in ischemic stroke
    • Nakase, T. et al. Neuroprotective role of astrocytic gap junctions in ischemic stroke. Cell Commun. Adhes. 10, 413-417 (2003).
    • (2003) Cell Commun. Adhes. , vol.10 , pp. 413-417
    • Nakase, T.1
  • 117
    • 0042122377 scopus 로고    scopus 로고
    • Astrocytic gap junctions composed of connexin 43 reduce apoptotic neuronal damage in cerebral ischemia
    • Nakase, T., Fushiki, S. & Naus, C. C. Astrocytic gap junctions composed of connexin 43 reduce apoptotic neuronal damage in cerebral ischemia. Stroke 34, 1987-1993 (2003).
    • (2003) Stroke , vol.34 , pp. 1987-1993
    • Nakase, T.1    Fushiki, S.2    Naus, C.C.3
  • 118
    • 0032175749 scopus 로고    scopus 로고
    • Gap-junction-mediated propagation and amplification of cell injury
    • Lin, J. H. et al. Gap-junction-mediated propagation and amplification of cell injury. Nature Neurosci. 1, 494-500 (1998).
    • (1998) Nature Neurosci. , vol.1 , pp. 494-500
    • Lin, J.H.1
  • 119
    • 0036470097 scopus 로고    scopus 로고
    • Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury
    • Frantseva, M. V. et al. Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury. J. Neurosci. 22, 644-653 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 644-653
    • Frantseva, M.V.1
  • 121
    • 48449084169 scopus 로고    scopus 로고
    • Connexin 43 mimetic peptides reduce swelling, astrogliosis, and neuronal cell death after spinal cord injury
    • O'Carroll, S. J., Alkadhi, M., Nicholson, L. F. & Green, C. R. Connexin 43 mimetic peptides reduce swelling, astrogliosis, and neuronal cell death after spinal cord injury. Cell Commun. Adhes. 15, 27-42 (2008).
    • (2008) Cell Commun. Adhes. , vol.15 , pp. 27-42
    • O'Carroll, S.J.1    Alkadhi, M.2    Nicholson, L.F.3    Green, C.R.4
  • 122
    • 52049127024 scopus 로고    scopus 로고
    • Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury
    • Cronin, M., Anderson, P. N., Cook, J. E., Green, C. R. & Becker, D. L. Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury. Mol. Cell Neurosci. 39, 152-160 (2008).
    • (2008) Mol. Cell Neurosci. , vol.39 , pp. 152-160
    • Cronin, M.1    Anderson, P.N.2    Cook, J.E.3    Green, C.R.4    Becker, D.L.5
  • 123
    • 34548203204 scopus 로고    scopus 로고
    • Astrocytes potentiate transmitter release at single hippocampal synapses
    • Perea, G. & Araque, A. Astrocytes potentiate transmitter release at single hippocampal synapses. Science 317, 1083-1086 (2007).
    • (2007) Science , vol.317 , pp. 1083-1086
    • Perea, G.1    Araque, A.2
  • 124
    • 58149472202 scopus 로고    scopus 로고
    • 2+-dependent glutamate release
    • Santello, M. & Volterra, A. Synaptic modulation by astrocytes via Ca2+-dependent glutamate release. Neuroscience 158, 253-259 (2009).
    • (2009) Neuroscience , vol.158 , pp. 253-259
    • Santello, M.1    Volterra, A.2
  • 125
    • 0035234296 scopus 로고    scopus 로고
    • How to close a gap junction channel. Efficacies and potencies of uncoupling agents
    • Rozental, R., Srinivas, M. & Spray, D. C. How to close a gap junction channel. Efficacies and potencies of uncoupling agents. Methods Mol. Biol. 154, 447-476 (2001).
    • (2001) Methods Mol. Biol. , vol.154 , pp. 447-476
    • Rozental, R.1    Srinivas, M.2    Spray, D.C.3
  • 126
    • 0036888975 scopus 로고    scopus 로고
    • Prospects for rational development of pharmacological gap junction channel blockers
    • Spray, D. C., Rozental, R. & Srinivas, M. Prospects for rational development of pharmacological gap junction channel blockers. Curr. Drug Targets 3, 455-464 (2002).
    • (2002) Curr. Drug Targets , vol.3 , pp. 455-464
    • Spray, D.C.1    Rozental, R.2    Srinivas, M.3
  • 128
    • 64749092065 scopus 로고    scopus 로고
    • Engineered lentiviral vector targeting astrocytes in vivo
    • Colin, A. et al. Engineered lentiviral vector targeting astrocytes in vivo. Glia 57, 667-679 (2009).
    • (2009) Glia , vol.57 , pp. 667-679
    • Colin, A.1
  • 129
    • 33750300467 scopus 로고    scopus 로고
    • Functional connexin "hemichannels": A critical appraisal
    • Spray, D. C., Ye, Z. C. & Ransom, B. R. Functional connexin "hemichannels": a critical appraisal. Glia 54, 758-773 (2006).
    • (2006) Glia , vol.54 , pp. 758-773
    • Spray, D.C.1    Ye, Z.C.2    Ransom, B.R.3
  • 131
    • 0037531231 scopus 로고    scopus 로고
    • Functional hemichannels in astrocytes: A novel mechanism of glutamate release
    • Ye, Z. C., Wyeth, M. S., Baltan-Tekkok, S. & Ransom, B. R. Functional hemichannels in astrocytes: a novel mechanism of glutamate release. J. Neurosci. 23, 3588-3596 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 3588-3596
    • Ye, Z.C.1    Wyeth, M.S.2    Baltan-Tekkok, S.3    Ransom, B.R.4
  • 132
    • 37249015389 scopus 로고    scopus 로고
    • Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia
    • Retamal, M. A. et al. Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia. J. Neurosci. 27, 13781-13792 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 13781-13792
    • Retamal, M.A.1
  • 133
    • 33847687710 scopus 로고    scopus 로고
    • Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes
    • Rana, S. & Dringen, R. Gap junction hemichannel-mediated release of glutathione from cultured rat astrocytes. Neurosci. Lett. 415, 45-48 (2007).
    • (2007) Neurosci. Lett. , vol.415 , pp. 45-48
    • Rana, S.1    Dringen, R.2
  • 134
    • 44849141495 scopus 로고    scopus 로고
    • Stimulated efflux of amino acids and glutathione from cultured hippocampal slices by omission of extracellular calcium: Likely involvement of connexin hemichannels
    • Stridh, M. H., Tranberg, M., Weber, S. G., Blomstrand, F. & Sandberg, M. Stimulated efflux of amino acids and glutathione from cultured hippocampal slices by omission of extracellular calcium: likely involvement of connexin hemichannels. J. Biol. Chem. 283, 10347-10356 (2008).
    • (2008) J. Biol. Chem. , vol.283 , pp. 10347-10356
    • Stridh, M.H.1    Tranberg, M.2    Weber, S.G.3    Blomstrand, F.4    Sandberg, M.5
  • 135
    • 0141533205 scopus 로고    scopus 로고
    • New roles for astrocytes: Redefining the functional architecture of the brain
    • Nedergaard, M., Ransom, B. & Goldman, S. A. New roles for astrocytes: redefining the functional architecture of the brain. Trends Neurosci. 26, 523-530 (2003).
    • (2003) Trends Neurosci. , vol.26 , pp. 523-530
    • Nedergaard, M.1    Ransom, B.2    Goldman, S.A.3
  • 136
    • 0034602889 scopus 로고    scopus 로고
    • Formation of heterotypic gap junction channels by connexins 40 and 43
    • Valiunas, V., Weingart, R. & Brink, P. R. Formation of heterotypic gap junction channels by connexins 40 and 43. Circ. Res. 86, E42-E49 (2000).
    • (2000) Circ. Res. , vol.86
    • Valiunas, V.1    Weingart, R.2    Brink, P.R.3
  • 137
    • 33748929432 scopus 로고    scopus 로고
    • Expression of pannexin1 in the CNS of adult mouse: Cellular localization and effect of 4-aminopyridine-induced seizures
    • Zappala, A. et al. Expression of pannexin1 in the CNS of adult mouse: cellular localization and effect of 4-aminopyridine-induced seizures. Neuroscience 141, 167-178 (2006).
    • (2006) Neuroscience , vol.141 , pp. 167-178
    • Zappala, A.1
  • 138
    • 85045378796 scopus 로고    scopus 로고
    • A ubiquitous family of putative gap junction molecules
    • Panchin, Y. et al. A ubiquitous family of putative gap junction molecules. Curr. Biol. 10, R473-R474 (2000).
    • (2000) Curr. Biol. , vol.10
    • Panchin, Y.1
  • 140
    • 0028178965 scopus 로고
    • i oscillations derived from a detailed kinetic model: A Hodgkin-Huxley like formalism
    • Li, Y. X. & Rinzel, J. Equations for InsP3 receptor-mediated [Ca2+]i oscillations derived from a detailed kinetic model: a Hodgkin-Huxley like formalism. J. Theor. Biol. 166, 461-473 (1994).
    • (1994) J. Theor. Biol. , vol.166 , pp. 461-473
    • Li, Y.X.1    Rinzel, J.2
  • 141
    • 34147123579 scopus 로고    scopus 로고
    • Modeling synaptic transmission of the tripartite synapse
    • Nadkarni, S. & Jung, P. Modeling synaptic transmission of the tripartite synapse. Phys. Biol. 4, 1-9 (2007).
    • (2007) Phys. Biol. , vol.4 , pp. 1-9
    • Nadkarni, S.1    Jung, P.2
  • 142
    • 1042277405 scopus 로고    scopus 로고
    • Spontaneous oscillations of dressed neurons: A new mechanism for epilepsy?
    • Nadkarni, S. & Jung, P. Spontaneous oscillations of dressed neurons: a new mechanism for epilepsy? Phys. Rev. Lett. 91, 268101 (2003).
    • (2003) Phys. Rev. Lett. , vol.91 , pp. 268101
    • Nadkarni, S.1    Jung, P.2
  • 143
    • 4444320120 scopus 로고    scopus 로고
    • Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors
    • Fellin, T. et al. Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors. Neuron 43, 729-743 (2004).
    • (2004) Neuron , vol.43 , pp. 729-743
    • Fellin, T.1
  • 144
    • 0030786791 scopus 로고    scopus 로고
    • Distribution of astroglia in glomeruli of the rat main olfactory bulb: Exclusion from the sensory subcompartment of neuropil
    • Chao, T. I., Kasa, P. & Wolff, J. R. Distribution of astroglia in glomeruli of the rat main olfactory bulb: exclusion from the sensory subcompartment of neuropil. J. Comp. Neurol. 388, 191-210 (1997).
    • (1997) J. Comp. Neurol. , vol.388 , pp. 191-210
    • Chao, T.I.1    Kasa, P.2    Wolff, J.R.3
  • 145
    • 0027410649 scopus 로고
    • Astrocyte subtypes in the rat olfactory bulb: Morphological heterogeneity and differential laminar distribution
    • Bailey, M. S. & Shipley, M. T. Astrocyte subtypes in the rat olfactory bulb: morphological heterogeneity and differential laminar distribution. J. Comp. Neurol. 328, 501-526 (1993).
    • (1993) J. Comp. Neurol. , vol.328 , pp. 501-526
    • Bailey, M.S.1    Shipley, M.T.2
  • 146
    • 0033464868 scopus 로고    scopus 로고
    • Astrocytes couple synaptic activity to glucose utilization in the brain
    • Magistretti, P. J. & Pellerin, L. Astrocytes couple synaptic activity to glucose utilization in the brain. News Physiol. Sci. 14, 177-182 (1999).
    • (1999) News Physiol. Sci. , vol.14 , pp. 177-182
    • Magistretti, P.J.1    Pellerin, L.2
  • 147
    • 61649125348 scopus 로고    scopus 로고
    • Electrical coupling between hippocampal astrocytes in rat brain slices
    • Meme, W., Vandecasteele, M., Giaume, C. & Venance, L. Electrical coupling between hippocampal astrocytes in rat brain slices. Neurosci. Res. 63, 236-243 (2009).
    • (2009) Neurosci. Res. , vol.63 , pp. 236-243
    • Meme, W.1    Vandecasteele, M.2    Giaume, C.3    Venance, L.4
  • 148
    • 33750841524 scopus 로고    scopus 로고
    • Ethanol effects on electrophysiological properties of astrocytes in striatal brain slices
    • Adermark, L. & Lovinger, D. M. Ethanol effects on electrophysiological properties of astrocytes in striatal brain slices. Neuropharmacology 51, 1099-1108 (2006).
    • (2006) Neuropharmacology , vol.51 , pp. 1099-1108
    • Adermark, L.1    Lovinger, D.M.2
  • 149
    • 0036872333 scopus 로고    scopus 로고
    • Gap junctions and connexin expression in the normal and pathological central nervous system
    • Rouach, N. et al. Gap junctions and connexin expression in the normal and pathological central nervous system. Biol. Cell 94, 457-475 (2002).
    • (2002) Biol. Cell , vol.94 , pp. 457-475
    • Rouach, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.