Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1

Assay and Drug Development Technologies

Volumn 11, Issue 9-10, 2013, Pages 532-543

  Raphemot, Rene ^a   Kadakia, Rishin J ^a   Olsen, Michelle L ^b   Banerjee, Sreedatta ^a   Days, Emily ^a   Smith, Stephen S ^c   Weaver, C David ^a   Denton, Jerod S ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c MOLECULAR DEVICES CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,3 DIPHENYL N (1 PHENYLETHYL)PROPAN 1 AMINE; AMINE; DIMETHYL SULFOXIDE; FLUOXETINE; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR4.1; POTASSIUM CHANNEL BLOCKING AGENT; PRENYLAMINE; TETRACYCLINE; THALLIUM; UNCLASSIFIED DRUG; VU 717;

ANIMAL CELL; ARTICLE; ASSAY; ASTROCYTE CULTURE; AUTOMATED PATCH CLAMP; CELL STRAIN HEK293; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; FLUORESCENCE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IC 50; INTRACELLULAR RECORDING; MOLECULAR LIBRARY; NONHUMAN; RAT; THALLIUM FLUX ASSAY;

ANIMALS; ASTROCYTES; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; FLOW CYTOMETRY; FLOW INJECTION ANALYSIS; HEK293 CELLS; HUMANS; ION CHANNEL GATING; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, FLUORESCENCE;

EID: 84890947554     PISSN: 1540658X     EISSN: 15578127     Source Type: Journal    
DOI: 10.1089/adt.2013.544     Document Type: Article

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