Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: Increased gap junctional function and expression

Journal of Neurochemistry

Volumn 86, Issue 3, 2003, Pages 687-699

  Samoilova, Marina ^a,b   Li, Jianxue ^a,b   Pelletier, Marc R ^a,b   Wentlandt, Kirsten ^a,b   Adamchik, Yana ^a   Naus, Christian C ^c   Carlen, Peter L ^a,b,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY HEALTH NETWORK   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

Bicuculline; Carbenoxolone; Connexins; Epilepsy; Gap junction

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; BICUCULLINE METHIODIDE; CARBENOXOLONE; CONNEXIN 26; CONNEXIN 32; CONNEXIN 36; CONNEXIN 43; MESSENGER RNA; OCTANOL; OLEANOLIC ACID; PROTEIN C FOS;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEACHING; BRAIN SLICE; CONTROLLED STUDY; DRUG EXPOSURE; ELECTROPHYSIOLOGY; EPILEPSY; EPILEPTIC DISCHARGE; FLUORESCENCE; GAP JUNCTION; HIPPOCAMPUS; HYPOTHESIS; IMMUNOBLOTTING; LONG TERM EXPOSURE; MALE; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PYRAMIDAL NERVE CELL; RAT; RIBONUCLEASE PROTECTION ASSAY; STATISTICAL SIGNIFICANCE; SYNAPSE; TISSUE CULTURE; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; BICUCULLINE; CARBENOXOLONE; CONNEXIN 43; CONNEXINS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ELECTRIC STIMULATION; EPILEPSY; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GABA ANTAGONISTS; GAP JUNCTIONS; GENE EXPRESSION; HIPPOCAMPUS; MALE; NERVE TISSUE PROTEINS; OCTANOLS; PATCH-CLAMP TECHNIQUES; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; RNA, MESSENGER; TIME FACTORS;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0041802936     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01893.x     Document Type: Article

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