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Volumn 1487, Issue , 2012, Pages 54-60

Curious and contradictory roles of glial connexins and pannexins in epilepsy

Author keywords

Connexin; Connexin hemichannel; Epilepsy; Gap junction; Glial cell; Pannexin

Indexed keywords

ANTICONVULSIVE AGENT; CONNEXIN 43; GAP JUNCTION PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; PANNEXIN; POTASSIUM; TRANSCRIPTOME; UNCLASSIFIED DRUG;

EID: 84869499315     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.06.059     Document Type: Review
Times cited : (30)

References (86)
  • 1
    • 33644836912 scopus 로고    scopus 로고
    • Participation of cortical glial cells to the genesis of spike-wave seizures
    • F. Amzica Participation of cortical glial cells to the genesis of spike-wave seizures Adv. Neurol. 97 2006 173 182
    • (2006) Adv. Neurol. , vol.97 , pp. 173-182
    • Amzica, F.1
  • 2
    • 0036785457 scopus 로고    scopus 로고
    • Glial and neuronal interactions during slow wave and paroxysmal activities in the neocortex
    • F. Amzica, and M. Massimini Glial and neuronal interactions during slow wave and paroxysmal activities in the neocortex Cereb. Cortex 12 2002 1101 1113
    • (2002) Cereb. Cortex , vol.12 , pp. 1101-1113
    • Amzica, F.1    Massimini, M.2
  • 3
    • 0036469942 scopus 로고    scopus 로고
    • Spatial buffering during slow and paroxysmal sleep oscillations in cortical networks of glial cells in vivo
    • F. Amzica, M. Massimini, and A. Manfridi Spatial buffering during slow and paroxysmal sleep oscillations in cortical networks of glial cells in vivo J. Neurosci. 22 3 2002 1042 1053 (Pubitemid 34141784)
    • (2002) Journal of Neuroscience , vol.22 , Issue.3 , pp. 1042-1053
    • Amzica, F.1    Massimini, M.2    Manfridi, A.3
  • 4
    • 0034950760 scopus 로고    scopus 로고
    • Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex
    • E. Aronica, J.A. Gorter, G.H. Jansen, S. Leenstra, B. Yankaya, and D. Troost Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex Acta Neuropathol. 101 2001 449 459 (Pubitemid 32600134)
    • (2001) Acta Neuropathologica , vol.101 , Issue.5 , pp. 449-459
    • Aronica, E.1    Gorter, J.A.2    Jansen, G.H.3    Leenstra, S.4    Yankaya, B.5    Troost, D.6
  • 5
    • 0242380301 scopus 로고    scopus 로고
    • New roles for astrocytes: Gap junction hemichannels have something to communicate
    • DOI 10.1016/j.tins.2003.09.008
    • M.V. Bennett, J.E. Contreras, F.F. Bukauskas, and J.C. Sáez New roles for astrocytes: gap junction hemichannels have something to communicate Trends Neurosci. 26 2003 610 617 (Pubitemid 37338369)
    • (2003) Trends in Neurosciences , vol.26 , Issue.11 , pp. 610-617
    • Bennett, M.V.L.1    Contreras, J.E.2    Bukauskas, F.F.3    Saez, J.C.4
  • 6
    • 0032169291 scopus 로고    scopus 로고
    • Properties of human glial cells associated with epileptic seizure foci
    • DOI 10.1016/S0920-1211(98)00059-X, PII S092012119800059X
    • A. Bordey, and H. Sontheimer Properties of human glial cells associated with epileptic seizure foci Epilepsy Res. 32 1-2 1998 286 303 (Pubitemid 28419497)
    • (1998) Epilepsy Research , vol.32 , Issue.1-2 , pp. 286-303
    • Bordey, A.1    Sontheimer, H.2
  • 7
    • 33748759806 scopus 로고    scopus 로고
    • The effects of octanol on penicillin induced epileptiform activity in rats: An in vivo study
    • DOI 10.1016/j.eplepsyres.2006.06.010, PII S0920121106002427
    • M.O. Bostanci, and F. Baǧirici The effects of octanol on penicillin induced epileptiform activity in rats: An in vivo study Epilepsy Res. 71 2-3 2006 188 194 (Pubitemid 44416196)
    • (2006) Epilepsy Research , vol.71 , Issue.2-3 , pp. 188-194
    • Bostanci, M.O.1    Bagirici, F.2
  • 8
    • 33846840608 scopus 로고    scopus 로고
    • Anticonvulsive effects of quinine on penicillin-induced epileptiform activity: An in vivo study
    • DOI 10.1016/j.seizure.2006.11.007, PII S1059131106002202
    • M.O. Bostanci, and F. Bagirici Anticonvulsive effects of quinine on penicillin-induced epileptiform activity: An in vivo study Seizure 16 2 2007 166 172 (Pubitemid 46211177)
    • (2007) Seizure , vol.16 , Issue.2 , pp. 166-172
    • Bostanci, M.O.1    Bagirici, F.2
  • 9
    • 0030950814 scopus 로고    scopus 로고
    • Termination of epileptic afterdischarge in the hippocampus
    • A. Bragin, M. Penttonen, and G. Buzsáki Termination of epileptic afterdischarge in the hippocampus J. Neurosci. 17 7 1997 2567 2579 (Pubitemid 27137422)
    • (1997) Journal of Neuroscience , vol.17 , Issue.7 , pp. 2567-2579
    • Bragin, A.1    Penttonen, M.2    Buzsaki, G.3
  • 12
    • 69449102409 scopus 로고    scopus 로고
    • Astrocytic dysfunction in epileptogenesis: Consequence of altered potassium and glutamate homeostasis?
    • Y. David, L.P. Cacheaux, S. Ivens, E. Lapilover, U. Heinemann, D. Kaufer, and A. Friedman Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis? J. Neurosci. 29 34 2009 10588 10599
    • (2009) J. Neurosci. , vol.29 , Issue.34 , pp. 10588-10599
    • David, Y.1    Cacheaux, L.P.2    Ivens, S.3    Lapilover, E.4    Heinemann, U.5    Kaufer, D.6    Friedman, A.7
  • 15
    • 33645530200 scopus 로고    scopus 로고
    • Effects of potassium concentration on firing patterns of low-calcium epileptiform activity in anesthetized rat hippocampus: Inducing of persistent spike activity
    • Z. Feng, and D.M. Durand Effects of potassium concentration on firing patterns of low-calcium epileptiform activity in anesthetized rat hippocampus: inducing of persistent spike activity Epilepsia 47 2006 727 736
    • (2006) Epilepsia , vol.47 , pp. 727-736
    • Feng, Z.1    Durand, D.M.2
  • 16
    • 0036498359 scopus 로고    scopus 로고
    • Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy
    • DOI 10.1016/S0006-8993(01)03289-9, PII S0006899301032899
    • C.G. Fonseca, C.R. Green, and L.F. Nicholson Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy Brain Res. 929 1 2002 105 116 (Pubitemid 34164415)
    • (2002) Brain Research , vol.929 , Issue.1 , pp. 105-116
    • Fonseca, C.G.1    Green, C.R.2    Nicholson, L.F.B.3
  • 17
    • 67650465533 scopus 로고    scopus 로고
    • Blood-brain barrier breakdown-inducing astrocytic transformation: Novel targets for the prevention of epilepsy
    • A. Friedman, D. Kaufer, and U. Heinemann Blood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy Epilepsy Res. 85 2009 142 149
    • (2009) Epilepsy Res. , vol.85 , pp. 142-149
    • Friedman, A.1    Kaufer, D.2    Heinemann, U.3
  • 18
    • 52649097998 scopus 로고    scopus 로고
    • Potassium dynamics in the epileptic cortex: New insights on an old topic
    • F. Fröhlich, M. Bazhenov, V. Iragui-Madoz, and T.J. Sejnowski Potassium dynamics in the epileptic cortex: new insights on an old topic Neuroscientist 14 2008 422 433
    • (2008) Neuroscientist , vol.14 , pp. 422-433
    • Fröhlich, F.1    Bazhenov, M.2    Iragui-Madoz, V.3    Sejnowski, T.J.4
  • 19
    • 27244443051 scopus 로고    scopus 로고
    • Quinine, a blocker of neuronal Cx36 channels, suppresses seizure activity in rat neocortex in vivo
    • DOI 10.1111/j.1528-1167.2005.00254.x
    • Z. Gajda, Z. Szupera, G. Blazsó, and M. Szente Quinine, a blocker of neuronal cx36 channels, suppresses seizure activity in rat neocortex in vivo Epilepsia 46 10 2005 1581 1591 (Pubitemid 44921931)
    • (2005) Epilepsia , vol.46 , Issue.10 , pp. 1581-1591
    • Gajda, Z.1    Szupera, Z.2    Blazso, G.3    Szente, M.4
  • 20
    • 33744466299 scopus 로고    scopus 로고
    • The functional significance of gap junction channels in the epileptogenicity and seizure susceptibility of juvenile rats
    • Z. Gajda, E. Hermesz, E. Gyengési, Z. Szupera, and M. Szente The functional significance of gap junction channels in the epileptogenicity and seizure susceptibility of juvenile rats Epilepsia 47 6 2006 1009 1922
    • (2006) Epilepsia , vol.47 , Issue.6 , pp. 1009-1922
    • Gajda, Z.1    Hermesz, E.2    Gyengési, E.3    Szupera, Z.4    Szente, M.5
  • 23
    • 33646008886 scopus 로고    scopus 로고
    • Effects in vitro and in vivo of a gap junction blocker on epileptiform activities in a genetic model of absence epilepsy
    • S. Gigout, J. Louvel, and R. Pumain Effects in vitro and in vivo of a gap junction blocker on epileptiform activities in a genetic model of absence epilepsy Epilepsy Res 69 1 2006 15 29
    • (2006) Epilepsy Res , vol.69 , Issue.1 , pp. 15-29
    • Gigout, S.1    Louvel, J.2    Pumain, R.3
  • 24
    • 84890924627 scopus 로고    scopus 로고
    • The human brain in numbers: A linearly scaled-up primate brain
    • S. Herculano-Houzel The human brain in numbers: A linearly scaled-up primate brain Front. Hum. Neurosci. 3 2009 31
    • (2009) Front. Hum. Neurosci. , vol.3 , pp. 31
    • Herculano-Houzel, S.1
  • 25
    • 0022586049 scopus 로고
    • Extracellular calcium and potassium concentration changes in chronic epileptic brain tissue
    • U. Heinemann, A. Konnerth, R. Pumain, and W.J. Wadman Extracellular calcium and potassium concentration changes in chronic epileptic brain tissue Adv. Neurol. 44 1986 641 661
    • (1986) Adv. Neurol. , vol.44 , pp. 641-661
    • Heinemann, U.1    Konnerth, A.2    Pumain, R.3    Wadman, W.J.4
  • 26
    • 0017362119 scopus 로고
    • Extracellular free calcium and potassium during paroxysmal activity in the cerebral cortex of the cat
    • U. Heinemann, H.D. Lux, and M.J. Gutnick Extracellular free calcium and potassium during paroxysmal activity in the cerebral cortex of the cat Exp. Brain Res. 27 1977 237 243 (Pubitemid 8057332)
    • (1977) Experimental Brain Research , vol.27 , Issue.3-4 , pp. 237-243
    • Heinemann, U.1    Lux, H.D.2    Gutnick, M.J.3
  • 29
    • 66149173401 scopus 로고    scopus 로고
    • Pannexin 1: The molecular substrate of astrocyte hemichannels
    • R. Iglesias, G. Dahl, F. Qiu, D.C. Spray, and E. Scemes Pannexin 1: the molecular substrate of astrocyte hemichannels J. Neurosci. 29 21 2009 7092 7097
    • (2009) J. Neurosci. , vol.29 , Issue.21 , pp. 7092-7097
    • Iglesias, R.1    Dahl, G.2    Qiu, F.3    Spray, D.C.4    Scemes, E.5
  • 30
    • 38449112392 scopus 로고    scopus 로고
    • Astrocytic function and its alteration in the epileptic brain
    • DOI 10.1111/j.1528-1167.2008.01505.x
    • R. Jabs, G. Seifert, and C. Steinhäuser Astrocytic function and its alteration in the epileptic brain Epilepsia 49 2 2008 3 12 (Pubitemid 351143761)
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 2 , pp. 3-12
    • Jabs, R.1    Seifert, G.2    Steinhauser, C.3
  • 31
    • 0036796629 scopus 로고    scopus 로고
    • Anticonvulsant actions of gap junctional blockers in an in vitro seizure model
    • S.S. Jahromi, K. Wentlandt, S. Piran, and P.L. Carlen Anticonvulsant actions of gap junctional blockers in an in vitro seizure model J. Neurophysiol. 88 4 2002 1893 1902 (Pubitemid 35191190)
    • (2002) Journal of Neurophysiology , vol.88 , Issue.4 , pp. 1893-1902
    • Jahromi, S.S.1    Wentlandt, K.2    Piran, S.3    Carlen, P.L.4
  • 32
    • 0030951062 scopus 로고    scopus 로고
    • Role of intrinsic burst firing, potassium accumulation, and electrical coupling in the elevated potassium model of hippocampal epilepsy
    • M.S. Jensen, and Y. Yaari Role of intrinsic burst firing, potassium accumulation, and electrical coupling in the elevated potassium model of hippocampal epilepsy J. Neurophysiol. 77 1997 1224 1233 (Pubitemid 27137020)
    • (1997) Journal of Neurophysiology , vol.77 , Issue.3 , pp. 1224-1233
    • Jensen, M.S.1    Yaari, Y.2
  • 33
    • 41149100582 scopus 로고    scopus 로고
    • Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter
    • DOI 10.1038/nn2060, PII NN2060
    • R. Káradóttir, N.B. Hamilton, Y. Bakiri, and D. Attwell Spiking and nonspiking classes of oligodendrocyte precursor glia in CNS white matter Nat. Neurosci. 11 2008 450 456 (Pubitemid 351441876)
    • (2008) Nature Neuroscience , vol.11 , Issue.4 , pp. 450-456
    • Karadottir, R.1    Hamilton, N.B.2    Bakiri, Y.3    Attwell, D.4
  • 35
    • 77949546914 scopus 로고    scopus 로고
    • Functions of mature mammalian astrocytes: A current view
    • H.K. Kimelberg Functions of mature mammalian astrocytes: A current view Neuroscientist 16 1 2010 79 106
    • (2010) Neuroscientist , vol.16 , Issue.1 , pp. 79-106
    • Kimelberg, H.K.1
  • 36
    • 9344266325 scopus 로고    scopus 로고
    • Potassium buffering in the central nervous system
    • DOI 10.1016/j.neuroscience.2004.06.008, PII S0306452204004737, Brain Water Homeostasis
    • P. Kofuji, and E.A. Newman Potassium buffering in the central nervous system Neuroscience 129 2004 1045 1056 (Pubitemid 39556255)
    • (2004) Neuroscience , vol.129 , Issue.4 , pp. 1045-1056
    • Kofuji, P.1    Newman, E.A.2
  • 37
    • 20344382308 scopus 로고    scopus 로고
    • Potassium homeostasis in the ischemic brain
    • DOI 10.1002/glia.20145
    • J.A. Leis, L.K. Bekar, and W. Walz Potassium homeostasis in the ischemic brain Glia 50 2005 407 416 (Pubitemid 40780844)
    • (2005) GLIA , vol.50 , Issue.4 , pp. 407-416
    • Leis, J.A.1    Bekar, L.K.2    Walz, W.3
  • 39
    • 0036198673 scopus 로고    scopus 로고
    • Reduced cortical synaptic plasticity and GluR1 expression associated with fragile X mental retardation protein deficiency
    • DOI 10.1006/mcne.2001.1085
    • J. Li, J.L. Perez Velazquez, M. Pelletier, and P.L. Carlen Reduced cortical GluR1 expression and synaptic plasticity associated with the absence of the Fragile X mental retardation protein Mol. Cell. Neurosci. 19 2002 138 151 (Pubitemid 34211895)
    • (2002) Molecular and Cellular Neuroscience , vol.19 , Issue.2 , pp. 138-151
    • Li, J.1    Pelletier, M.R.2    Perez Velazquez, J.-L.3    Carlen, P.L.4
  • 40
    • 65549144456 scopus 로고    scopus 로고
    • Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions
    • I. Maezawa, S. Swanberg, D. Harvey, J.M. LaSalle, and L.W. Jin Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions J. Neurosci. 29 2009 5051 5061
    • (2009) J. Neurosci. , vol.29 , pp. 5051-5061
    • Maezawa, I.1    Swanberg, S.2    Harvey, D.3    Lasalle, J.M.4    Jin, L.W.5
  • 41
    • 75749152627 scopus 로고    scopus 로고
    • Non-junction functions of pannexin-1 channels
    • B.A. MacVicar, and R.J. Thompson Non-junction functions of pannexin-1 channels Trends Neurosci. 33 2010 93 102
    • (2010) Trends Neurosci. , vol.33 , pp. 93-102
    • MacVicar, B.A.1    Thompson, R.J.2
  • 42
    • 77957264564 scopus 로고    scopus 로고
    • Differential effects of trimethylamine and quinine on seizures induced by 4-aminopyridine administration in the entorhinal cortex of vigilant rats
    • L. Medina-Ceja, and C. Ventura-Mejía Differential effects of trimethylamine and quinine on seizures induced by 4-aminopyridine administration in the entorhinal cortex of vigilant rats Seizure 19 2010 507 513
    • (2010) Seizure , vol.19 , pp. 507-513
    • Medina-Ceja, L.1    Ventura-Mejía, C.2
  • 43
    • 33750327152 scopus 로고    scopus 로고
    • Vesicular transmitter release from astrocytes
    • DOI 10.1002/glia.20367
    • V. Montana, E.B. Malarkey, C. Verderio, M. Matteoli, and V. Parpura Vesicular transmitter release from astrocytes Glia 54 2006 700 715 (Pubitemid 44629633)
    • (2006) GLIA , vol.54 , Issue.7 , pp. 700-715
    • Montana, V.1    Malarkey, E.B.2    Verderio, C.3    Matteoli, M.4    Parpura, V.5
  • 45
    • 2942614082 scopus 로고    scopus 로고
    • Update on connexins and gap junctions in neurons and glia in the mammalian nervous system
    • DOI 10.1016/j.brainresrev.2004.05.005, PII S0165017304000694, Chemical and Electrical Synapses
    • J.I. Nagy, F.E. Dudek, and J.E. Rash Update on connexins and gap junctions in neurons and glia in the mammalian nervous system Brain Res. Brain Res. Rev. 47 2004 191 215 (Pubitemid 39574320)
    • (2004) Brain Research Reviews , vol.47 , Issue.1-3 , pp. 191-215
    • Nagy, J.I.1    Dudek, F.E.2    Rash, J.E.3
  • 46
    • 0026090172 scopus 로고
    • Gap junction gene expression in human seizure disorder
    • C.C. Naus, J.F. Bechberger, and D.L. Paul Gap junction gene expression in human seizure disorder Exp. Neurol. 111 2 1991 198 203
    • (1991) Exp. Neurol. , vol.111 , Issue.2 , pp. 198-203
    • Naus, C.C.1    Bechberger, J.F.2    Paul, D.L.3
  • 47
    • 33748807065 scopus 로고    scopus 로고
    • Astrocytic complexity distinguishes the human brain
    • DOI 10.1016/j.tins.2006.08.004, PII S0166223606001755
    • N.A. Oberheim, X. Wang, S. Goldman, and M. Nedergaard Astrocytic complexity distinguishes the human brain Trends Neurosci. 29 2006 547 553 (Pubitemid 44416461)
    • (2006) Trends in Neurosciences , vol.29 , Issue.10 , pp. 547-553
    • Oberheim, N.A.1    Wang, X.2    Goldman, S.3    Nedergaard, M.4
  • 49
    • 80051759671 scopus 로고    scopus 로고
    • ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels
    • J.A. Orellana, N. Froger, P. Ezan, J.X. Jiang, M.V. Bennett, C.C. Naus, C. Giaume, and J.C. Sáez ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels J. Neurochem. 118 2011 826 840
    • (2011) J. Neurochem. , vol.118 , pp. 826-840
    • Orellana, J.A.1    Froger, N.2    Ezan, P.3    Jiang, J.X.4    Bennett, M.V.5    Naus, C.C.6    Giaume, C.7    Sáez, J.C.8
  • 54
    • 0034141742 scopus 로고    scopus 로고
    • Gap junctions, synchrony and seizures
    • DOI 10.1016/S0166-2236(99)01497-6, PII S0166223699014976
    • J.L. Perez Velazquez, and P.L. Carlen Gap junctions, neural synchrony, and seizures TINS 23 2000 68 74 (Pubitemid 30084763)
    • (2000) Trends in Neurosciences , vol.23 , Issue.2 , pp. 68-74
    • Perez Velazquez, J.L.1    Carlen, P.L.2
  • 55
    • 37249015389 scopus 로고    scopus 로고
    • Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia
    • DOI 10.1523/JNEUROSCI.2042-07.2007
    • A. Retamal, N. Froger, N. Palacios-Prado, P. Ezan, P.J. Sáez, J.C. Sáez, and C. Giaume Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia J. Neurosci. 27 2007 13781 13792 (Pubitemid 350278255)
    • (2007) Journal of Neuroscience , vol.27 , Issue.50 , pp. 13781-13792
    • Retamal, M.A.1    Froger, N.2    Palacios-Prado, N.3    Ezan, P.4    Saez, P.J.5    Saez, J.C.6    Giaume, C.7
  • 56
    • 57349185900 scopus 로고    scopus 로고
    • Astroglial metabolic networks sustain hippocampal synaptic transmission
    • N. Rouach, A. Koulakoff, V. Abudara, K. Willecke, and C. Giaume Astroglial metabolic networks sustain hippocampal synaptic transmission Science 322 5907 2008 1551 1555
    • (2008) Science , vol.322 , Issue.5907 , pp. 1551-1555
    • Rouach, N.1    Koulakoff, A.2    Abudara, V.3    Willecke, K.4    Giaume, C.5
  • 57
    • 0041802936 scopus 로고    scopus 로고
    • Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: Increased gap junctional function and expression
    • DOI 10.1046/j.1471-4159.2003.01893.x
    • M. Samoilova, J. Li, M.R. Pelletier, K. Wentlandt, Y. Adamchik, C.C.G. Naus, and P.L. Carlen Epileptiform activity in hippocampal slice cultures exposed chronically to bicuculline: increased gap junctional function and expression J. Neurochem. 86 2003 687 699 (Pubitemid 36897449)
    • (2003) Journal of Neurochemistry , vol.86 , Issue.3 , pp. 687-699
    • Samoilova, M.1    Li, J.2    Pelletier, M.R.3    Wentlandt, K.4    Adamchik, Y.5    Naus, C.C.6    Carlen, P.L.7
  • 58
    • 41149164595 scopus 로고    scopus 로고
    • Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures
    • M. Samoilova, K. Wentland, Y. Adamchik, A.A. Velumian, and P.L. Carlen Connexin 43 mimetic peptides inhibit spontaneous epileptiform activity in organotypic hippocampal slice cultures Exp. Neurol. 210 2008 762 775
    • (2008) Exp. Neurol. , vol.210 , pp. 762-775
    • Samoilova, M.1    Wentland, K.2    Adamchik, Y.3    Velumian, A.A.4    Carlen, P.L.5
  • 60
    • 38449106511 scopus 로고    scopus 로고
    • Early glial dysfunction in epilepsy
    • DOI 10.1111/j.1528-1167.2008.01504.x
    • R. Schwarcz Early glial dysfunction in epilepsy Epilepsia 49 2 2008 1 2 (Pubitemid 351143760)
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 2 , pp. 1-2
    • Schwarcz, R.1
  • 62
    • 4544312032 scopus 로고    scopus 로고
    • Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex
    • DOI 10.1523/JNEUROSCI.1751-04.2004
    • E. Seiffert, J.P. Dreier, S. Ivens, I. Bechmann, O. Tomkins, U. Heinemann, and A. Friedman Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex J. Neurosci. 24 2004 7829 7836 (Pubitemid 39215686)
    • (2004) Journal of Neuroscience , vol.24 , Issue.36 , pp. 7829-7836
    • Seiffert, E.1    Dreier, J.P.2    Ivens, S.3    Bechmann, I.4    Tomkins, O.5    Heinemann, U.6    Friedman, A.7
  • 63
    • 63549102673 scopus 로고    scopus 로고
    • The role of altered tissue osmolality on the characteristics and propagation of seizure activity in the intact isolated mouse hippocampus
    • E. Shahar, M. Derchansky, and P.L. Carlen The role of altered tissue osmolality on the characteristics and propagation of seizure activity in the intact isolated mouse hippocampus Clin. Neurophysiol. 120 2009 673 678
    • (2009) Clin. Neurophysiol. , vol.120 , pp. 673-678
    • Shahar, E.1    Derchansky, M.2    Carlen, P.L.3
  • 64
    • 62949246675 scopus 로고    scopus 로고
    • Intracranial stimulation therapy for epilepsy
    • T.L. Skarpaas, and M.J. Morrell Intracranial stimulation therapy for epilepsy Neurotherapeutics 6 2009 238 243
    • (2009) Neurotherapeutics , vol.6 , pp. 238-243
    • Skarpaas, T.L.1    Morrell, M.J.2
  • 65
    • 9344248393 scopus 로고    scopus 로고
    • The neurobiology of glia in the context of water and ion homeostasis
    • DOI 10.1016/j.neuroscience.2004.09.053, PII S0306452204008462, Brain Water Homeostasis
    • M. Simard, and M. Nedergaard The neurobiology of glia in the context of water and ion homeostasis Neuroscience 129 2004 877 896 (Pubitemid 39556241)
    • (2004) Neuroscience , vol.129 , Issue.4 , pp. 877-896
    • Simard, M.1    Nedergaard, M.2
  • 66
    • 0016421458 scopus 로고
    • Electrophysiology of neuroglia
    • G.G. Somjen Electrophysiology of neuroglia Annu. Rev. Physiol. 37 1975 163 190
    • (1975) Annu. Rev. Physiol. , vol.37 , pp. 163-190
    • Somjen, G.G.1
  • 67
    • 0036107388 scopus 로고    scopus 로고
    • Ion regulation in the brain: Implications for pathophysiology
    • G.G. Somjen Ion regulation in the brain: implications for pathophysiology Neuroscientist 8 2002 254 267 (Pubitemid 34538793)
    • (2002) Neuroscientist , vol.8 , Issue.3 , pp. 254-267
    • Somjen, G.G.1
  • 68
    • 84862327508 scopus 로고    scopus 로고
    • Astrocyte dysfunction in temporal lobe epilepsy: K(+) channels and gap junction coupling
    • C. Steinhäuser, G. Seifert, and P. Bedner Astrocyte dysfunction in temporal lobe epilepsy: K(+) channels and gap junction coupling Glia 60 8 2012 1192 1202
    • (2012) Glia , vol.60 , Issue.8 , pp. 1192-1202
    • Steinhäuser, C.1    Seifert, G.2    Bedner, P.3
  • 69
    • 33745400402 scopus 로고    scopus 로고
    • Hippocampal electrical stimulation in mesial temporal lobe epilepsy
    • DOI 10.1212/01.wnl.0000209300.49308.8f, PII 0000611420060523000009
    • J.F. Tellez-Zenteno, R.S. McLachlan, A. Parrent, C.S. Kubu, and S. Wiebe Hippocampal electrical stimulation in mesial temporal lobe epilepsy Neurology 66 2006 1490 1494 (Pubitemid 43958541)
    • (2006) Neurology , vol.66 , Issue.10 , pp. 1490-1494
    • Tellez-Zenteno, J.F.1    McLachlan, R.S.2    Parrent, A.3    Kubu, C.S.4    Wiebe, S.5
  • 70
    • 60849101949 scopus 로고    scopus 로고
    • Connexin and pannexin hemichannels of neurons and astrocytes
    • R.J. Thompson, and B.A. Macvicar Connexin and pannexin hemichannels of neurons and astrocytes Channels (Austin) 2 2008 81 86
    • (2008) Channels (Austin) , vol.2 , pp. 81-86
    • Thompson, R.J.1    MacVicar, B.A.2
  • 73
    • 79953030273 scopus 로고    scopus 로고
    • Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex
    • P. Tsai, and M. Sahin Mechanisms of neurocognitive dysfunction and therapeutic considerations in tuberous sclerosis complex Curr. Opin. Neurol. 24 2011 106 113
    • (2011) Curr. Opin. Neurol. , vol.24 , pp. 106-113
    • Tsai, P.1    Sahin, M.2
  • 76
    • 68149174964 scopus 로고    scopus 로고
    • Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice
    • L.J. Voss, G. Jacobson, J.W. Sleigh, A. Steyn-Ross, and M. Steyn-Ross Excitatory effects of gap junction blockers on cerebral cortex seizure-like activity in rats and mice Epilepsia 50 2009 1971 1978
    • (2009) Epilepsia , vol.50 , pp. 1971-1978
    • Voss, L.J.1    Jacobson, G.2    Sleigh, J.W.3    Steyn-Ross, A.4    Steyn-Ross, M.5
  • 77
    • 33745003688 scopus 로고    scopus 로고
    • The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus
    • DOI 10.1523/JNEUROSCI.0037-06.2006
    • A. Wallraff, R. Köhling, U. Heinemann, M. Theis, K. Willecke, and C. Steinhäuser The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus J. Neurosci. 26 20 2006 5438 5447 (Pubitemid 44318396)
    • (2006) Journal of Neuroscience , vol.26 , Issue.20 , pp. 5438-5447
    • Wallraff, A.1    Kohling, R.2    Heinemann, U.3    Theis, M.4    Willecke, K.5    Steinhauser, C.6
  • 78
    • 0021018205 scopus 로고
    • Functional interactions between neurons and astrocytes. II. Potassium homeostasis at the cellular level
    • W. Walz, and L. Hertz Functional interactions between neurons and astrocytes. II. Potassium homeostasis at the cellular level Prog Neurobiol. 20 1-2 1983 133 183 (Pubitemid 14200562)
    • (1983) Progress in Neurobiology , vol.20 , Issue.1-2 , pp. 133-183
    • Walz, W.1    Hertz, L.2
  • 79
    • 0036794743 scopus 로고    scopus 로고
    • Chloride/anion channels in glial cell membranes
    • DOI 10.1002/glia.10125
    • W. Walz Chloride/anion channels in glial cell membranes Glia 40 2002 1 10 (Pubitemid 35181339)
    • (2002) GLIA , vol.40 , Issue.1 , pp. 1-10
    • Walz, W.1
  • 80
    • 56949092726 scopus 로고    scopus 로고
    • The astrocyte odyssey
    • D.D. Wang, and A. Bordey The astrocyte odyssey Prog. Neurobiol. 86 4 2008 342 367
    • (2008) Prog. Neurobiol. , vol.86 , Issue.4 , pp. 342-367
    • Wang, D.D.1    Bordey, A.2
  • 81
    • 42149112453 scopus 로고    scopus 로고
    • Astrocytes in the Epileptic Brain
    • DOI 10.1016/j.neuron.2008.04.002, PII S0896627308003061
    • J. Wetherington, G. Serrano, and R. Dingledine Astrocytes in the epileptic brain Neuron 58 2008 168 178 (Pubitemid 351539007)
    • (2008) Neuron , vol.58 , Issue.2 , pp. 168-178
    • Wetherington, J.1    Serrano, G.2    Dingledine, R.3
  • 82
    • 64449086356 scopus 로고    scopus 로고
    • Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex
    • L. Xu, L.H. Zeng, and M. Wong Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex Neurobiol. Dis. 34 2009 291 299
    • (2009) Neurobiol. Dis. , vol.34 , pp. 291-299
    • Xu, L.1    Zeng, L.H.2    Wong, M.3
  • 83
    • 84871502182 scopus 로고    scopus 로고
    • Expression and function of Cx32 and Cx43 junctions in medically intractable temporal lobe epilepsy in human
    • (article in Chinese)
    • L.F. Yao, Z.K. Wang, Z.G. Wang, D. Sui, and L.M. Zhang Expression and function of Cx32 and Cx43 junctions in medically intractable temporal lobe epilepsy in human Zhonghua Yi Xue Za Zhi 89 2009 3058 3060 (article in Chinese)
    • (2009) Zhonghua Yi Xue Za Zhi , vol.89 , pp. 3058-3060
    • Yao, L.F.1    Wang, Z.K.2    Wang, Z.G.3    Sui, D.4    Zhang, L.M.5
  • 84
    • 78650176658 scopus 로고    scopus 로고
    • Dose-dependent protective effect of connexin43 mimetic peptide against neurodegeneration in an ex vivo model of epileptiform lesion
    • J.J. Yoon, C.R. Green, S.J. O'Carroll, and L.F. Nicholson Dose-dependent protective effect of connexin43 mimetic peptide against neurodegeneration in an ex vivo model of epileptiform lesion. Epilepsy Res. 92 2-3 2010 153 162
    • (2010) Epilepsy Res. , vol.92 , Issue.23 , pp. 153-162
    • Yoon, J.J.1    Green, C.R.2    O'Carroll, S.J.3    Nicholson, L.F.4
  • 86
    • 34547562467 scopus 로고    scopus 로고
    • Regulated ATP release from astrocytes through lysosome exocytosis
    • DOI 10.1038/ncb1620, PII NCB1620
    • Z. Zhang, G. Chen, W. Zhou, A. Song, T. Xu, Q. Luo, W. Wang, X.S. Gu, and S. Duan Regulated ATP release from astrocytes through lysosome exocytosis Nat. Cell Biol. 9 2007 945 953 (Pubitemid 47190449)
    • (2007) Nature Cell Biology , vol.9 , Issue.8 , pp. 945-953
    • Zhang, Z.1    Chen, G.2    Zhou, W.3    Song, A.4    Xu, T.5    Luo, Q.6    Wang, W.7    Gu, X.-S.8    Duan, S.9


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