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Volumn 10, Issue 1, 2015, Pages 143-160

Delivery of therapeutics using nanocarriers for targeting cancer cells and cancer stem cells

Author keywords

cancer stem cells; cancer therapy; drug delivery; gene delivery; nanocarriers; protein delivery

Indexed keywords

NANOCARRIER; NANOPARTICLE;

EID: 84921491505     PISSN: 17435889     EISSN: 17486963     Source Type: Journal    
DOI: 10.2217/nnm.14.154     Document Type: Review
Times cited : (22)

References (143)
  • 2
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot T, Sirard C, Vormoor J et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367(6464), 645-648 (1994).
    • (1994) Nature , vol.367 , Issue.6464 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 3
    • 39449088496 scopus 로고    scopus 로고
    • Identification and expansion of the tumorigenic lung cancer stem cell population
    • Eramo A, Lotti F, Sette G et al. Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ. 15(3), 504-514 (2007).
    • (2007) Cell Death Differ. , vol.15 , Issue.3 , pp. 504-514
    • Eramo, A.1    Lotti, F.2    Sette, G.3
  • 4
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res. 65(23), 10946-10951 (2005).
    • (2005) Cancer Res. , vol.65 , Issue.23 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 5
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • Singh SK, Clarke ID, Terasaki M et al. Identification of a cancer stem cell in human brain tumors. Cancer Res. 63(18), 5821-5828 (2003).
    • (2003) Cancer Res. , vol.63 , Issue.18 , pp. 5821-5828
    • Singh, S.K.1    Clarke, I.D.2    Terasaki, M.3
  • 6
    • 33847052127 scopus 로고    scopus 로고
    • Identification of pancreatic cancer stem cells
    • Li C, Heidt DG, Dalerba P et al. Identification of pancreatic cancer stem cells. Cancer Res. 67(3), 1030-1037 (2007).
    • (2007) Cancer Res. , vol.67 , Issue.3 , pp. 1030-1037
    • Li, C.1    Heidt, D.G.2    Dalerba, P.3
  • 8
    • 66149175569 scopus 로고    scopus 로고
    • Identification of gastric cancer stem cells using the cell surface marker CD44
    • Takaishi S, Okumura T, Tu S et al. Identification of gastric cancer stem cells using the cell surface marker CD44. Stem Cells 27(5), 1006-1020 (2009).
    • (2009) Stem Cells , vol.27 , Issue.5 , pp. 1006-1020
    • Takaishi, S.1    Okumura, T.2    Tu, S.3
  • 9
    • 33947095683 scopus 로고    scopus 로고
    • CD133, one of the markers of cancer stem cells in Hep2 cell line
    • Zhou L, Wei X, Cheng L, Tian J, Jiang JJ. CD133, one of the markers of cancer stem cells in Hep2 cell line. Laryngoscope 117(3), 455-460 (2007).
    • (2007) Laryngoscope , vol.117 , Issue.3 , pp. 455-460
    • Zhou, L.1    Wei, X.2    Cheng, L.3    Tian, J.4    Jiang, J.J.5
  • 10
    • 4644306516 scopus 로고    scopus 로고
    • A distinct "side population" of cells with high drug efflux capacity in human tumor cells
    • Hirschmann-Jax C, Foster A, Wulf G et al. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc. Natl Acad. Sci. USA 101(39), 14228-14233 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.39 , pp. 14228-14233
    • Hirschmann-Jax, C.1    Foster, A.2    Wulf, G.3
  • 11
    • 33746625091 scopus 로고    scopus 로고
    • Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian inhibiting substance responsiveness
    • Szotek PP, Pieretti-Vanmarcke R, Masiakos PT et al. Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian inhibiting substance responsiveness. Proc. Natl Acad. Sci. USA 103(30), 11154-11159 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.30 , pp. 11154-11159
    • Szotek, P.P.1    Pieretti-Vanmarcke, R.2    Masiakos, P.T.3
  • 12
    • 84875320058 scopus 로고    scopus 로고
    • Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden
    • Abubaker K, Latifi A, Luwor R et al. Short-term single treatment of chemotherapy results in the enrichment of ovarian cancer stem cell-like cells leading to an increased tumor burden. Mol. Cancer 12(1), 24 (2013).
    • (2013) Mol. Cancer , vol.12 , Issue.1 , pp. 24
    • Abubaker, K.1    Latifi, A.2    Luwor, R.3
  • 13
    • 84873045443 scopus 로고    scopus 로고
    • Radiation treatment generates therapy-resistant cancer stem cells from less aggressive breast cancer cells
    • Printz C. Radiation treatment generates therapy-resistant cancer stem cells from less aggressive breast cancer cells. Cancer 118(13), 3225-3225 (2012).
    • (2012) Cancer , vol.118 , Issue.13 , pp. 3225-3225
    • Printz, C.1
  • 14
    • 16844368698 scopus 로고    scopus 로고
    • Tumour stem cells and drug resistance
    • Dean M, Fojo T, Bates S. Tumour stem cells and drug resistance. Nat. Rev. Cancer 5(4), 275-284 (2005).
    • (2005) Nat. Rev. Cancer , vol.5 , Issue.4 , pp. 275-284
    • Dean, M.1    Fojo, T.2    Bates, S.3
  • 15
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 8(10), 755-768 (2008).
    • (2008) Nat. Rev. Cancer , vol.8 , Issue.10 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 16
    • 77953126613 scopus 로고    scopus 로고
    • The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor
    • Riccioni R, Dupuis ML, Bernabei M et al. The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor. Blood Cells Mol. Dis. 45(1), 86-92 (2010).
    • (2010) Blood Cells Mol. Dis. , vol.45 , Issue.1 , pp. 86-92
    • Riccioni, R.1    Dupuis, M.L.2    Bernabei, M.3
  • 17
    • 80052552395 scopus 로고    scopus 로고
    • Therapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted nanoparticles for the treatment of multi-drug resistant cancer
    • Milane L, Duan Z, Amiji M. Therapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted nanoparticles for the treatment of multi-drug resistant cancer. PLoS ONE 6(9), e24075 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.9
    • Milane, L.1    Duan, Z.2    Amiji, M.3
  • 18
    • 64349122714 scopus 로고    scopus 로고
    • Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar
    • KüHnle M, Egger M, MüLler C et al. Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar. J. Med. Chem. 52(4), 1190-1197 (2009).
    • (2009) J. Med. Chem. , vol.52 , Issue.4 , pp. 1190-1197
    • Kühnle, M.1    Egger, M.2    Müller, C.3
  • 19
    • 58849097669 scopus 로고    scopus 로고
    • Preferential killing of breast tumor initiating cells by N, N-diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine/ tesmilifene
    • Deng T, Liu JC, Pritchard KI, Eisen A, Zacksenhaus E. Preferential killing of breast tumor initiating cells by N, N-diethyl-2-[4-(phenylmethyl) phenoxy] ethanamine/ tesmilifene. Clin. Cancer Res. 15(1), 119-130 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , Issue.1 , pp. 119-130
    • Deng, T.1    Liu, J.C.2    Pritchard, K.I.3    Eisen, A.4    Zacksenhaus, E.5
  • 20
    • 70350236538 scopus 로고    scopus 로고
    • Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission
    • Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Res. 69(19), 7507-7511 (2009).
    • (2009) Cancer Res. , vol.69 , Issue.19 , pp. 7507-7511
    • Hirsch, H.A.1    Iliopoulos, D.2    Tsichlis, P.N.3    Struhl, K.4
  • 21
    • 77955559259 scopus 로고    scopus 로고
    • Targeting breast stem cells with the cancer preventive compounds curcumin and piperine
    • Kakarala M, Brenner DE, Korkaya H et al. Targeting breast stem cells with the cancer preventive compounds curcumin and piperine. Breast Cancer Res. Treat. 122(3), 777-785 (2010).
    • (2010) Breast Cancer Res. Treat. , vol.122 , Issue.3 , pp. 777-785
    • Kakarala, M.1    Brenner, D.E.2    Korkaya, H.3
  • 22
    • 84862783302 scopus 로고    scopus 로고
    • Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells
    • Chen D, Pamu S, Cui Q, Chan TH, Dou QP. Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells. Bioorg. Med. Chem. 20(9), 3031-3037 (2012).
    • (2012) Bioorg. Med. Chem. , vol.20 , Issue.9 , pp. 3031-3037
    • Chen, D.1    Pamu, S.2    Cui, Q.3    Chan, T.H.4    Dou, Q.P.5
  • 23
    • 77951730125 scopus 로고    scopus 로고
    • Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells
    • Li Y, Zhang T, Korkaya H et al. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clin. Cancer Res. 16(9), 2580-2590 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , Issue.9 , pp. 2580-2590
    • Li, Y.1    Zhang, T.2    Korkaya, H.3
  • 24
    • 66149192405 scopus 로고    scopus 로고
    • A phase i study of the P-glycoprotein antagonist tariquidar in combination with vinorelbine
    • Abraham J, Edgerly M, Wilson R et al. A phase I study of the P-glycoprotein antagonist tariquidar in combination with vinorelbine. Clin. Cancer Res. 15(10), 3574-3582 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , Issue.10 , pp. 3574-3582
    • Abraham, J.1    Edgerly, M.2    Wilson, R.3
  • 25
    • 23644452472 scopus 로고    scopus 로고
    • Phase II study of tariquidar, a selective Pglycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma
    • Pusztai L, Wagner P, Ibrahim N et al. Phase II study of tariquidar, a selective Pglycoprotein inhibitor, in patients with chemotherapy-resistant, advanced breast carcinoma. Cancer 104(4), 682-691 (2005).
    • (2005) Cancer , vol.104 , Issue.4 , pp. 682-691
    • Pusztai, L.1    Wagner, P.2    Ibrahim, N.3
  • 26
    • 77949323798 scopus 로고    scopus 로고
    • Incorporating the antidiabetic drug metformin in HER2-positive breast cancer treated with neo-adjuvant chemotherapy and trastuzumab: An ongoing clinical-translational research experience at the Catalan Institute of Oncology
    • Martin-Castillo B, Dorca J, Vazquez-Martin A et al. Incorporating the antidiabetic drug metformin in HER2-positive breast cancer treated with neo-adjuvant chemotherapy and trastuzumab: an ongoing clinical-translational research experience at the Catalan Institute of Oncology. Ann. Oncol. 21(1), 187-189 (2010).
    • (2010) Ann. Oncol. , vol.21 , Issue.1 , pp. 187-189
    • Martin-Castillo, B.1    Dorca, J.2    Vazquez-Martin, A.3
  • 27
    • 84899135577 scopus 로고    scopus 로고
    • Phase II randomized trial of neoadjuvant metformin plus letrozole versus placebo plus letrozole for estrogen receptor positive postmenopausal breast cancer (METEOR)
    • Kim J, Lim W, Kim E-K et al. Phase II randomized trial of neoadjuvant metformin plus letrozole versus placebo plus letrozole for estrogen receptor positive postmenopausal breast cancer (METEOR). BMC Cancer 14(1), 170 (2014).
    • (2014) BMC Cancer , vol.14 , Issue.1 , pp. 170
    • Kim, J.1    Lim, W.2    Kim, E.-K.3
  • 29
    • 79959989874 scopus 로고    scopus 로고
    • Salinomycin induces calpain and cytochrome c-mediated neuronal cell death
    • Boehmerle W, Endres M. Salinomycin induces calpain and cytochrome c-mediated neuronal cell death. Cell Death Dis. 2(6), e168 (2011).
    • (2011) Cell Death Dis. , vol.2 , Issue.6 , pp. e168
    • Boehmerle, W.1    Endres, M.2
  • 30
    • 2342441532 scopus 로고    scopus 로고
    • Metformin induced acute pancreatitis precipitated by renal failure
    • Mallick S. Metformin induced acute pancreatitis precipitated by renal failure. Postgrad. Med. J. 80(942), 239-240 (2004).
    • (2004) Postgrad. Med. J. , vol.80 , Issue.942 , pp. 239-240
    • Mallick, S.1
  • 31
    • 0027521967 scopus 로고
    • Phenformin-induced lactic acidosis: A forgotten adverse drug reaction
    • Mcguinness M, Talbert R. Phenformin-induced lactic acidosis: a forgotten adverse drug reaction. Ann. Pharmacother. 27(10), 1183-1187 (1993).
    • (1993) Ann. Pharmacother. , vol.27 , Issue.10 , pp. 1183-1187
    • McGuinness, M.1    Talbert, R.2
  • 33
    • 84891373113 scopus 로고    scopus 로고
    • Co-delivery of chemotherapeutic drugs with vitamin e TPGS by porous PLGA nanoparticles for enhanced chemotherapy against multi-drug resistance
    • Zhu H, Chen H, Zeng X et al. Co-delivery of chemotherapeutic drugs with vitamin E TPGS by porous PLGA nanoparticles for enhanced chemotherapy against multi-drug resistance. Biomaterials 35(7), 2391-2400 (2014).
    • (2014) Biomaterials , vol.35 , Issue.7 , pp. 2391-2400
    • Zhu, H.1    Chen, H.2    Zeng, X.3
  • 34
    • 84899451579 scopus 로고    scopus 로고
    • Surface-modulated and thermoresponsive polyphosphoester nanoparticles for enhanced intracellular drug delivery
    • Li Y, Wang F, Sun T, Du J, Yang X, Wang J. Surface-modulated and thermoresponsive polyphosphoester nanoparticles for enhanced intracellular drug delivery. Sci. China Chem. 57(4), 1-7 (2014).
    • (2014) Sci. China Chem. , vol.57 , Issue.4 , pp. 1-7
    • Li, Y.1    Wang, F.2    Sun, T.3    Du, J.4    Yang, X.5    Wang, J.6
  • 35
    • 84880512700 scopus 로고    scopus 로고
    • Development of a gene/drug dual delivery system for brain tumor therapy: Potent inhibition via RNA interference and synergistic effects
    • Lei C, Cui Y, Zheng L, Kah-Hoe Chow P, Wang C-H. Development of a gene/drug dual delivery system for brain tumor therapy: potent inhibition via RNA interference and synergistic effects. Biomaterials 34(30), 7483-7494 (2013).
    • (2013) Biomaterials , vol.34 , Issue.30 , pp. 7483-7494
    • Lei, C.1    Cui, Y.2    Zheng, L.3    Kah-Hoe Chow, P.4    Wang, C.-H.5
  • 36
    • 20744434748 scopus 로고    scopus 로고
    • Microencapsulated chitosan nanoparticles for lung protein delivery
    • Grenha A, Seijo B, Remuñán-López C. Microencapsulated chitosan nanoparticles for lung protein delivery. Eur. J. Pharm. Sci. 25(4), 427-437 (2005).
    • (2005) Eur. J. Pharm. Sci. , vol.25 , Issue.4 , pp. 427-437
    • Grenha, A.1    Seijo, B.2    Remuñán-López, C.3
  • 37
    • 66549120963 scopus 로고    scopus 로고
    • New generation of multifunctional nanoparticles for cancer imaging and therapy
    • Park K, Lee S, Kang E, Kim K, Choi K, Kwon IC. New generation of multifunctional nanoparticles for cancer imaging and therapy. Adv. Funct. Mat. 19(10), 1553-1566 (2009).
    • (2009) Adv. Funct. Mat. , vol.19 , Issue.10 , pp. 1553-1566
    • Park, K.1    Lee, S.2    Kang, E.3    Kim, K.4    Choi, K.5    Kwon, I.C.6
  • 38
    • 84899852334 scopus 로고    scopus 로고
    • Layer-by-layer nanoparticles as an efficient siRNA delivery vehicle for SPARC silencing
    • Tan YF, Mundargi RC, Chen MHA et al. Layer-by-layer nanoparticles as an efficient siRNA delivery vehicle for SPARC silencing. Small 10(9), 1790-1798 (2014).
    • (2014) Small , vol.10 , Issue.9 , pp. 1790-1798
    • Tan, Y.F.1    Mundargi, R.C.2    Chen, M.H.A.3
  • 39
    • 50249086003 scopus 로고    scopus 로고
    • Antibody targeting of camptothecin-loaded PLGA nanoparticles to tumor cells
    • Mccarron PA, Marouf WM, Quinn DJ et al. Antibody targeting of camptothecin-loaded PLGA nanoparticles to tumor cells. Bioconjug. Chem. 19(8), 1561-1569 (2008).
    • (2008) Bioconjug. Chem. , vol.19 , Issue.8 , pp. 1561-1569
    • McCarron, P.A.1    Marouf, W.M.2    Quinn, D.J.3
  • 40
    • 70350707597 scopus 로고    scopus 로고
    • The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
    • Patil YB, Swaminathan SK, Sadhukha T, Ma L, Panyam J. The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance. Biomaterials 31(2), 358-365 (2010).
    • (2010) Biomaterials , vol.31 , Issue.2 , pp. 358-365
    • Patil, Y.B.1    Swaminathan, S.K.2    Sadhukha, T.3    Ma, L.4    Panyam, J.5
  • 41
    • 84867503516 scopus 로고    scopus 로고
    • Surface charge switchable nanoparticles based on zwitterionic polymer for enhanced drug delivery to tumor
    • Yuan YY, Mao CQ, Du XJ, Du JZ, Wang F, Wang J. Surface charge switchable nanoparticles based on zwitterionic polymer for enhanced drug delivery to tumor. Adv. Mater. 24(40), 5476-5480 (2012).
    • (2012) Adv. Mater. , vol.24 , Issue.40 , pp. 5476-5480
    • Yuan, Y.Y.1    Mao, C.Q.2    Du, X.J.3    Du, J.Z.4    Wang, F.5    Wang, J.6
  • 42
    • 20944450473 scopus 로고    scopus 로고
    • NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel
    • Hamaguchi T, Matsumura Y, Suzuki M et al. NK105, a paclitaxel-incorporating micellar nanoparticle formulation, can extend in vivo antitumour activity and reduce the neurotoxicity of paclitaxel. Br. J. Cancer 92(7), 1240-1246 (2005).
    • (2005) Br. J. Cancer , vol.92 , Issue.7 , pp. 1240-1246
    • Hamaguchi, T.1    Matsumura, Y.2    Suzuki, M.3
  • 44
    • 67649342875 scopus 로고    scopus 로고
    • Temperature and pH-sensitive multicolored micellar complexes
    • Li YY, Cheng H, Zhu JL et al. Temperature and pH-sensitive multicolored micellar complexes. Adv. Mater. 21(23), 2402-2406 (2009).
    • (2009) Adv. Mater. , vol.21 , Issue.23 , pp. 2402-2406
    • Li, Y.Y.1    Cheng, H.2    Zhu, J.L.3
  • 45
    • 80455168058 scopus 로고    scopus 로고
    • Tailor-made dual pH-sensitive polymer-doxorubicin nanoparticles for efficient anticancer drug delivery
    • Du J-Z, Du X-J, Mao C-Q, Wang J. Tailor-made dual pH-sensitive polymer-doxorubicin nanoparticles for efficient anticancer drug delivery. J. Am. Chem. Soc. 133(44), 17560-17563 (2011).
    • (2011) J. Am. Chem. Soc. , vol.133 , Issue.44 , pp. 17560-17563
    • Du, J.-Z.1    Du, X.-J.2    Mao, C.-Q.3    Wang, J.4
  • 46
    • 14644439212 scopus 로고    scopus 로고
    • PH-triggered thermally responsive polymer core-shell nanoparticles for drug delivery
    • Soppimath KS, Tan DW, Yang YY. pH-triggered thermally responsive polymer core-shell nanoparticles for drug delivery. Adv. Mater. 17(3), 318-323 (2005).
    • (2005) Adv. Mater. , vol.17 , Issue.3 , pp. 318-323
    • Soppimath, K.S.1    Tan, D.W.2    Yang, Y.Y.3
  • 47
    • 79951642779 scopus 로고    scopus 로고
    • Dual-vectors of anti-cancer drugs and genes based on pH-sensitive micelles self-assembled from hybrid polypeptide copolymers
    • Li Y-Y, Hua S-H, Xiao W et al. Dual-vectors of anti-cancer drugs and genes based on pH-sensitive micelles self-assembled from hybrid polypeptide copolymers. J. Mater. Chem. 21(9), 3100-3106 (2011).
    • (2011) J. Mater. Chem. , vol.21 , Issue.9 , pp. 3100-3106
    • Li, Y.-Y.1    Hua, S.-H.2    Xiao, W.3
  • 48
    • 79958164983 scopus 로고    scopus 로고
    • Prevention of metastasis in a 4T1 murine breast cancer model by doxorubicin carried by folate conjugated pH sensitive polymeric micelles
    • Gao Z-G, Tian L, Hu J, Park I-S, Bae YH. Prevention of metastasis in a 4T1 murine breast cancer model by doxorubicin carried by folate conjugated pH sensitive polymeric micelles. J. Control. Release 152(1), 84-89 (2011).
    • (2011) J. Control. Release , vol.152 , Issue.1 , pp. 84-89
    • Gao, Z.-G.1    Tian, L.2    Hu, J.3    Park, I.-S.4    Bae, Y.H.5
  • 49
    • 79953028891 scopus 로고    scopus 로고
    • Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system
    • Lee SJ, Koo H, Lee D-E et al. Tumor-homing photosensitizer-conjugated glycol chitosan nanoparticles for synchronous photodynamic imaging and therapy based on cellular on/off system. Biomaterials 32(16), 4021-4029 (2011).
    • (2011) Biomaterials , vol.32 , Issue.16 , pp. 4021-4029
    • Lee, S.J.1    Koo, H.2    Lee, D.-E.3
  • 50
    • 67650741406 scopus 로고    scopus 로고
    • Self-assembled polymer nanostructures for delivery of anticancer therapeutics
    • Wiradharma N, Zhang Y, Venkataraman S, Hedrick JL, Yang YY. Self-assembled polymer nanostructures for delivery of anticancer therapeutics. Nano Today 4(4), 302-317 (2009).
    • (2009) Nano Today , vol.4 , Issue.4 , pp. 302-317
    • Wiradharma, N.1    Zhang, Y.2    Venkataraman, S.3    Hedrick, J.L.4    Yang, Y.Y.5
  • 51
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
    • Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control. Release 65(1), 271-284 (2000).
    • (2000) J. Control. Release , vol.65 , Issue.1 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5
  • 52
    • 33845791448 scopus 로고    scopus 로고
    • Bio-functional micelles self-assembled from a folate-conjugated block copolymer for targeted intracellular delivery of anticancer drugs
    • Liu S-Q, Wiradharma N, Gao S-J, Tong YW, Yang Y-Y. Bio-functional micelles self-assembled from a folate-conjugated block copolymer for targeted intracellular delivery of anticancer drugs. Biomaterials 28(7), 1423-1433 (2007).
    • (2007) Biomaterials , vol.28 , Issue.7 , pp. 1423-1433
    • Liu, S.-Q.1    Wiradharma, N.2    Gao, S.-J.3    Tong, Y.W.4    Yang, Y.-Y.5
  • 53
    • 57649124218 scopus 로고    scopus 로고
    • The co-delivery of paclitaxel and Herceptin using cationic micellar nanoparticles
    • Lee AL, Wang Y, Cheng HY, Pervaiz S, Yang YY. The co-delivery of paclitaxel and Herceptin using cationic micellar nanoparticles. Biomaterials 30(5), 919-927 (2009).
    • (2009) Biomaterials , vol.30 , Issue.5 , pp. 919-927
    • Lee, A.L.1    Wang, Y.2    Cheng, H.Y.3    Pervaiz, S.4    Yang, Y.Y.5
  • 54
    • 77955542791 scopus 로고    scopus 로고
    • A drug-loaded aptamer? Gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer
    • Kim D, Jeong YY, Jon S. A drug-loaded aptamer? gold nanoparticle bioconjugate for combined CT imaging and therapy of prostate cancer. ACS Nano 4(7), 3689-3696 (2010).
    • (2010) ACS Nano , vol.4 , Issue.7 , pp. 3689-3696
    • Kim, D.1    Jeong, Y.Y.2    Jon, S.3
  • 55
    • 79960933733 scopus 로고    scopus 로고
    • ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients
    • Wilson BJ, Schatton T, Zhan Q et al. ABCB5 identifies a therapy-refractory tumor cell population in colorectal cancer patients. Cancer Res. 71(15), 5307-5316 (2011).
    • (2011) Cancer Res. , vol.71 , Issue.15 , pp. 5307-5316
    • Wilson, B.J.1    Schatton, T.2    Zhan, Q.3
  • 57
    • 84861995326 scopus 로고    scopus 로고
    • Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells
    • Sachlos E, Risueño RM, Laronde S et al. Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell 149(6), 1284-1297 (2012).
    • (2012) Cell , vol.149 , Issue.6 , pp. 1284-1297
    • Sachlos, E.1    Risueño, R.M.2    Laronde, S.3
  • 58
    • 84884235663 scopus 로고    scopus 로고
    • Drug screening identifies niclosamide as an inhibitor of breast cancer stem-like cells
    • Wang Y-C, Chao T-K, Chang C-C, Yo Y-T, Yu M-H, Lai H-C. Drug screening identifies niclosamide as an inhibitor of breast cancer stem-like cells. PLoS ONE 8(9), e74538 (2013).
    • (2013) PLoS ONE , vol.8 , Issue.9
    • Wang, Y.-C.1    Chao, T.-K.2    Chang, C.-C.3    Yo, Y.-T.4    Yu, M.-H.5    Lai, H.-C.6
  • 59
    • 84859461497 scopus 로고    scopus 로고
    • Metformin and cancer stem cells: Old drug, new targets
    • Bednar F, Simeone DM. Metformin and cancer stem cells: old drug, new targets. Cancer Prev. Res. (Philadelphia) 5(3), 351-354 (2012).
    • (2012) Cancer Prev. Res. (Philadelphia) , vol.5 , Issue.3 , pp. 351-354
    • Bednar, F.1    Simeone, D.M.2
  • 60
    • 84870359511 scopus 로고    scopus 로고
    • Novel micelle formulation of curcumin for enhancing antitumor activity and inhibiting colorectal cancer stem cells
    • Wang K, Zhang T, Liu L et al. Novel micelle formulation of curcumin for enhancing antitumor activity and inhibiting colorectal cancer stem cells. Int. J. Nanomedicine 7, 4487 (2012).
    • (2012) Int. J. Nanomedicine , vol.7 , pp. 4487
    • Wang, K.1    Zhang, T.2    Liu, L.3
  • 61
    • 84861807248 scopus 로고    scopus 로고
    • Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog-Gli1 pathway
    • Zhang L, Li L, Jiao M et al. Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog-Gli1 pathway. Cancer Lett. 323(1), 48-57 (2012).
    • (2012) Cancer Lett. , vol.323 , Issue.1 , pp. 48-57
    • Zhang, L.1    Li, L.2    Jiao, M.3
  • 62
    • 84871980094 scopus 로고    scopus 로고
    • TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo
    • Perlstein B, Finniss SA, Miller C et al. TRAIL conjugated to nanoparticles exhibits increased anti-tumor activities in glioma cells and glioma stem cells in vitro and in vivo. Neuro Oncol. 15(1), 29-40 (2013).
    • (2013) Neuro Oncol. , vol.15 , Issue.1 , pp. 29-40
    • Perlstein, B.1    Finniss, S.A.2    Miller, C.3
  • 63
    • 84866116748 scopus 로고    scopus 로고
    • MicroRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase C&epsiv
    • Datta J, Smith A, Lang JC et al. microRNA-107 functions as a candidate tumor-suppressor gene in head and neck squamous cell carcinoma by downregulation of protein kinase C&epsiv. Oncogene 31(36), 4045-4053 (2011).
    • (2011) Oncogene , vol.31 , Issue.36 , pp. 4045-4053
    • Datta, J.1    Smith, A.2    Lang, J.C.3
  • 64
    • 84861669644 scopus 로고    scopus 로고
    • Doxil® - The first FDA-approved nano-drug: Lessons learned
    • Barenholz YC. Doxil® - the first FDA-approved nano-drug: lessons learned. J. Control. Release 160(2), 117-134 (2012).
    • (2012) J. Control. Release , vol.160 , Issue.2 , pp. 117-134
    • Barenholz, Y.C.1
  • 65
    • 67449084321 scopus 로고    scopus 로고
    • Preclinical and clinical studies of anticancer agent-incorporating polymer micelles
    • Matsumura Y, Kataoka K. Preclinical and clinical studies of anticancer agent-incorporating polymer micelles. Cancer Sci. 100(4), 572-579 (2009).
    • (2009) Cancer Sci. , vol.100 , Issue.4 , pp. 572-579
    • Matsumura, Y.1    Kataoka, K.2
  • 66
    • 84870324628 scopus 로고    scopus 로고
    • Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer
    • Wang K, Liu L, Zhang T et al. Oxaliplatin-incorporated micelles eliminate both cancer stem-like and bulk cell populations in colorectal cancer. Int. J. Nanomedicine 6, 3207 (2011).
    • (2011) Int. J. Nanomedicine , vol.6 , pp. 3207
    • Wang, K.1    Liu, L.2    Zhang, T.3
  • 67
    • 44649133215 scopus 로고    scopus 로고
    • A potential target associated with both cancer and cancer stem cells: A combination therapy for eradication of breast cancer using vinorelbine stealthy liposomes plus parthenolide stealthy liposomes
    • Liu Y, Lu W-L, Guo J et al. A potential target associated with both cancer and cancer stem cells: a combination therapy for eradication of breast cancer using vinorelbine stealthy liposomes plus parthenolide stealthy liposomes. J. Control. Release 129(1), 18-25 (2008).
    • (2008) J. Control. Release , vol.129 , Issue.1 , pp. 18-25
    • Liu, Y.1    Lu, W.-L.2    Guo, J.3
  • 68
    • 78650404347 scopus 로고    scopus 로고
    • Effects of stealth liposomal daunorubicin plus tamoxifen on the breast cancer and cancer stem cells
    • Guo J, Lu W-L. Effects of stealth liposomal daunorubicin plus tamoxifen on the breast cancer and cancer stem cells. J. Pharm. Pharm. Sci. 13(2), 136-151 (2010).
    • (2010) J. Pharm. Pharm. Sci. , vol.13 , Issue.2 , pp. 136-151
    • Guo, J.1    Lu, W.-L.2
  • 69
    • 80055112766 scopus 로고    scopus 로고
    • The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles
    • Zhang Y, Zhang H, Wang X, Wang J, Zhang X, Zhang Q. The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles. Biomaterials 33(2), 679-691 (2012).
    • (2012) Biomaterials , vol.33 , Issue.2 , pp. 679-691
    • Zhang, Y.1    Zhang, H.2    Wang, X.3    Wang, J.4    Zhang, X.5    Zhang, Q.6
  • 70
    • 84887626984 scopus 로고    scopus 로고
    • Co-delivery of thioridazine and doxorubicin using polymeric micelles for targeting both cancer cells and cancer stem cells
    • Ke X-Y, Lin Ng VW, Gao S-J, Tong YW, Hedrick JL, Yang YY. Co-delivery of thioridazine and doxorubicin using polymeric micelles for targeting both cancer cells and cancer stem cells. Biomaterials 35(3), 1096-108 (2013).
    • (2013) Biomaterials , vol.35 , Issue.3 , pp. 1096-1108
    • Ke, X.-Y.1    Lin Ng, V.W.2    Gao, S.-J.3    Tong, Y.W.4    Hedrick, J.L.5    Yang, Y.Y.6
  • 71
    • 84873453625 scopus 로고    scopus 로고
    • The effect of kinetic stability on biodistribution and anti-tumor efficacy of drug-loaded biodegradable polymeric micelles
    • Ebrahim Attia AB, Yang C, Tan JP et al. The effect of kinetic stability on biodistribution and anti-tumor efficacy of drug-loaded biodegradable polymeric micelles. Biomaterials 34(12), 3132-3140 (2013).
    • (2013) Biomaterials , vol.34 , Issue.12 , pp. 3132-3140
    • Ebrahim Attia, A.B.1    Yang, C.2    Tan, J.P.3
  • 72
    • 79951950284 scopus 로고    scopus 로고
    • All-trans retinoic acid stealth liposomes prevent the relapse of breast cancer arising from the cancer stem cells
    • Li R-J, Ying X, Zhang Y et al. All-trans retinoic acid stealth liposomes prevent the relapse of breast cancer arising from the cancer stem cells. J. Control. Release 149(3), 281-291 (2011).
    • (2011) J. Control. Release , vol.149 , Issue.3 , pp. 281-291
    • Li, R.-J.1    Ying, X.2    Zhang, Y.3
  • 73
    • 37249007368 scopus 로고    scopus 로고
    • Tagging alcohols with cyclic carbonate: A versatile equivalent of (meth) acrylate for ring-opening polymerization
    • Pratt RC, Nederberg F, Waymouth RM, Hedrick JL. Tagging alcohols with cyclic carbonate: a versatile equivalent of (meth) acrylate for ring-opening polymerization. Chem. Commun. (1), 114-116 (2008).
    • (2008) Chem. Commun. , Issue.1 , pp. 114-116
    • Pratt, R.C.1    Nederberg, F.2    Waymouth, R.M.3    Hedrick, J.L.4
  • 74
    • 33845253160 scopus 로고    scopus 로고
    • Exploration, optimization, and application of supramolecular thiourea-amine catalysts for the synthesis of lactide (co) polymers
    • Pratt RC, Lohmeijer BG, Long DA et al. Exploration, optimization, and application of supramolecular thiourea-amine catalysts for the synthesis of lactide (co) polymers. Macromolecules 39(23), 7863-7871 (2006).
    • (2006) Macromolecules , vol.39 , Issue.23 , pp. 7863-7871
    • Pratt, R.C.1    Lohmeijer, B.G.2    Long, D.A.3
  • 75
    • 78649909152 scopus 로고    scopus 로고
    • Supramolecular nanostructures designed for high cargo loading capacity and kinetic stability
    • Yang C, Tan JP, Cheng W et al. Supramolecular nanostructures designed for high cargo loading capacity and kinetic stability. Nano Today 5(6), 515-523 (2010).
    • (2010) Nano Today , vol.5 , Issue.6 , pp. 515-523
    • Yang, C.1    Tan, J.P.2    Cheng, W.3
  • 76
    • 79956315543 scopus 로고    scopus 로고
    • Thermoresponsive nanostructured polycarbonate block copolymers as biodegradable therapeutic delivery carriers
    • Kim SH, Tan JP, Fukushima K et al. Thermoresponsive nanostructured polycarbonate block copolymers as biodegradable therapeutic delivery carriers. Biomaterials 32(23), 5505-5514 (2011).
    • (2011) Biomaterials , vol.32 , Issue.23 , pp. 5505-5514
    • Kim, S.H.1    Tan, J.P.2    Fukushima, K.3
  • 77
    • 51049104302 scopus 로고    scopus 로고
    • Pharmacokinetics and biodistribution of nanoparticles
    • Li S-D, Huang L. Pharmacokinetics and biodistribution of nanoparticles. Mol. Pharm. 5(4), 496-504 (2008).
    • (2008) Mol. Pharm. , vol.5 , Issue.4 , pp. 496-504
    • Li, S.-D.1    Huang, L.2
  • 79
    • 84861902017 scopus 로고    scopus 로고
    • Lipid-based nanoparticle delivery of pre-miR-107 inhibits the tumorigenicity of head and neck squamous cell carcinoma
    • Piao L, Zhang M, Datta J et al. Lipid-based nanoparticle delivery of pre-miR-107 inhibits the tumorigenicity of head and neck squamous cell carcinoma. Mol. Ther. 20(6), 1261-1269 (2012).
    • (2012) Mol. Ther. , vol.20 , Issue.6 , pp. 1261-1269
    • Piao, L.1    Zhang, M.2    Datta, J.3
  • 80
    • 79751473114 scopus 로고    scopus 로고
    • The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
    • Liu C, Kelnar K, Liu B et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat. Med. 17(2), 211-215 (2011).
    • (2011) Nat. Med. , vol.17 , Issue.2 , pp. 211-215
    • Liu, C.1    Kelnar, K.2    Liu, B.3
  • 81
    • 84875740719 scopus 로고    scopus 로고
    • Systemic delivery of microRNA-34a for cancer stem cell therapy
    • Shi S, Han L, Gong T, Zhang Z, Sun X. Systemic delivery of microRNA-34a for cancer stem cell therapy. Angew. Chem. Int. Ed. Engl. 52(14), 3901-3905 (2013).
    • (2013) Angew. Chem. Int. Ed. Engl. , vol.52 , Issue.14 , pp. 3901-3905
    • Shi, S.1    Han, L.2    Gong, T.3    Zhang, Z.4    Sun, X.5
  • 82
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio MV, Ferracin M, Liu C-G et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 65(16), 7065-7070 (2005).
    • (2005) Cancer Res. , vol.65 , Issue.16 , pp. 7065-7070
    • Iorio, M.V.1    Ferracin, M.2    Liu, C.-G.3
  • 83
    • 34548746977 scopus 로고    scopus 로고
    • MicroRNA signatures in human ovarian cancer
    • Iorio MV, Visone R, Di Leva G et al. MicroRNA signatures in human ovarian cancer. Cancer Res. 67(18), 8699-8707 (2007).
    • (2007) Cancer Res. , vol.67 , Issue.18 , pp. 8699-8707
    • Iorio, M.V.1    Visone, R.2    Di Leva, G.3
  • 84
    • 67349149082 scopus 로고    scopus 로고
    • MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells
    • Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 137(4), 647-658 (2009).
    • (2009) Cell , vol.137 , Issue.4 , pp. 647-658
    • Xu, N.1    Papagiannakopoulos, T.2    Pan, G.3    Thomson, J.A.4    Kosik, K.S.5
  • 85
    • 83355166283 scopus 로고    scopus 로고
    • Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI
    • Yang Y-P, Chien Y, Chiou G-Y et al. Inhibition of cancer stem cell-like properties and reduced chemoradioresistance of glioblastoma using microRNA145 with cationic polyurethane-short branch PEI. Biomaterials 33(5), 1462-1476 (2012).
    • (2012) Biomaterials , vol.33 , Issue.5 , pp. 1462-1476
    • Yang, Y.-P.1    Chien, Y.2    Chiou, G.-Y.3
  • 86
    • 84862808036 scopus 로고    scopus 로고
    • Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial-mesenchymal transdifferentiation and cancer stem-like properties and in lung adenocarcinoma
    • Chiou G-Y, Cherng J-Y, Hsu H-S et al. Cationic polyurethanes-short branch PEI-mediated delivery of Mir145 inhibited epithelial-mesenchymal transdifferentiation and cancer stem-like properties and in lung adenocarcinoma. J. Control. Release 159(2), 240-250 (2012).
    • (2012) J. Control. Release , vol.159 , Issue.2 , pp. 240-250
    • Chiou, G.-Y.1    Cherng, J.-Y.2    Hsu, H.-S.3
  • 87
    • 70449708980 scopus 로고    scopus 로고
    • Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel
    • Liu C, Zhao G, Liu J et al. Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel. J. Control. Release 140(3), 277-283 (2009).
    • (2009) J. Control. Release , vol.140 , Issue.3 , pp. 277-283
    • Liu, C.1    Zhao, G.2    Liu, J.3
  • 88
    • 78149471362 scopus 로고    scopus 로고
    • Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells
    • Kato T, Natsume A, Toda H et al. Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells. Gene Ther. 17(11), 1363-1371 (2010).
    • (2010) Gene Ther. , vol.17 , Issue.11 , pp. 1363-1371
    • Kato, T.1    Natsume, A.2    Toda, H.3
  • 89
    • 84879604991 scopus 로고    scopus 로고
    • Targeted delivery of miR-200c/DOC to inhibit cancer stem cells and cancer cells by the gelatinases-stimuli nanoparticles
    • Liu Q, Li R-T, Qian H-Q et al. Targeted delivery of miR-200c/DOC to inhibit cancer stem cells and cancer cells by the gelatinases-stimuli nanoparticles. Biomaterials 34(29), 7191-7203 (2013).
    • (2013) Biomaterials , vol.34 , Issue.29 , pp. 7191-7203
    • Liu, Q.1    Li, R.-T.2    Qian, H.-Q.3
  • 90
    • 79551600015 scopus 로고    scopus 로고
    • Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
    • Takebe N, Harris PJ, Warren RQ, Ivy SP. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat. Rev. Clin. Oncol. 8(2), 97-106 (2011).
    • (2011) Nat. Rev. Clin. Oncol. , vol.8 , Issue.2 , pp. 97-106
    • Takebe, N.1    Harris, P.J.2    Warren, R.Q.3    Ivy, S.P.4
  • 91
    • 58749105627 scopus 로고    scopus 로고
    • Efficient delivery of Bcl-2-targeted siRNA using cationic polymer nanoparticles: Downregulating mRNA expression level and sensitizing cancer cells to anticancer drug
    • Beh CW, Seow WY, Wang Y et al. Efficient delivery of Bcl-2-targeted siRNA using cationic polymer nanoparticles: downregulating mRNA expression level and sensitizing cancer cells to anticancer drug. Biomacromolecules 10(1), 41-48 (2008).
    • (2008) Biomacromolecules , vol.10 , Issue.1 , pp. 41-48
    • Beh, C.W.1    Seow, W.Y.2    Wang, Y.3
  • 92
    • 84887972270 scopus 로고    scopus 로고
    • Targeted therapeutic effect of anti-ABCG2 antibody combined with nano silver and vincristine on mouse myeloma cancer stem cells
    • Dou J, He X, Liu Y et al. Targeted therapeutic effect of anti-ABCG2 antibody combined with nano silver and vincristine on mouse myeloma cancer stem cells. J. Nanopart. Res. 15(12), 1-12 (2013).
    • (2013) J. Nanopart. Res. , vol.15 , Issue.12 , pp. 1-12
    • Dou, J.1    He, X.2    Liu, Y.3
  • 93
    • 76649113726 scopus 로고    scopus 로고
    • CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts
    • Ginestier C, Liu S, Diebel ME et al. CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts. J. Clin. Invest. 120(2), 485 (2010).
    • (2010) J. Clin. Invest. , vol.120 , Issue.2 , pp. 485
    • Ginestier, C.1    Liu, S.2    Diebel, M.E.3
  • 94
    • 84866304417 scopus 로고    scopus 로고
    • Anti-tumor effects of the peptide TMTP1-GG-D (KLAKLAK) 2 on highly metastatic cancers
    • Ma X, Xi L, Luo D et al. Anti-tumor effects of the peptide TMTP1-GG-D (KLAKLAK) 2 on highly metastatic cancers. PLoS ONE 7(9), e42685 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.9
    • Ma, X.1    Xi, L.2    Luo, D.3
  • 95
    • 84881145625 scopus 로고    scopus 로고
    • Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway
    • Mcclements L, Yakkundi A, Papaspyropoulos A et al. Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway. Clin. Cancer Res. 19(14), 3881-3893 (2013).
    • (2013) Clin. Cancer Res. , vol.19 , Issue.14 , pp. 3881-3893
    • McClements, L.1    Yakkundi, A.2    Papaspyropoulos, A.3
  • 96
    • 81055127027 scopus 로고    scopus 로고
    • A6 peptide activates CD44 adhesive activity, induces FAK and MEK phosphorylation, and inhibits the migration and metastasis of CD44-expressing cells
    • Piotrowicz RS, Damaj BB, Hachicha M, Incardona F, Howell SB, Finlayson M. A6 peptide activates CD44 adhesive activity, induces FAK and MEK phosphorylation, and inhibits the migration and metastasis of CD44-expressing cells. Mol. Cancer Ther. 10(11), 2072-2082 (2011).
    • (2011) Mol. Cancer Ther. , vol.10 , Issue.11 , pp. 2072-2082
    • Piotrowicz, R.S.1    Damaj, B.B.2    Hachicha, M.3    Incardona, F.4    Howell, S.B.5    Finlayson, M.6
  • 97
    • 84893797666 scopus 로고    scopus 로고
    • Targeting head and neck cancer stem cells to overcome resistance to photon and carbon ion radiation
    • Bertrand G, Maalouf M, Boivin A et al. Targeting head and neck cancer stem cells to overcome resistance to photon and carbon ion radiation. Stem Cell Rev. 10(1), 114-126 (2014).
    • (2014) Stem Cell Rev. , vol.10 , Issue.1 , pp. 114-126
    • Bertrand, G.1    Maalouf, M.2    Boivin, A.3
  • 98
    • 84888013612 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer
    • Moon CM, Kwon JH, Kim JS et al. Nonsteroidal anti-inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer. Int. J. Cancer 134(3), 519-529 (2014).
    • (2014) Int. J. Cancer , vol.134 , Issue.3 , pp. 519-529
    • Moon, C.M.1    Kwon, J.H.2    Kim, J.S.3
  • 99
    • 84855837427 scopus 로고    scopus 로고
    • Curcumin nanoformulations: A future nanomedicine for cancer
    • Yallapu MM, Jaggi M, Chauhan SC. Curcumin nanoformulations: a future nanomedicine for cancer. Drug Discov. Today 17(1), 71-80 (2012).
    • (2012) Drug Discov. Today , vol.17 , Issue.1 , pp. 71-80
    • Yallapu, M.M.1    Jaggi, M.2    Chauhan, S.C.3
  • 100
    • 34248205135 scopus 로고    scopus 로고
    • Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): A novel strategy for human cancer therapy
    • Bisht S, Feldmann G, Soni S et al. Polymeric nanoparticle-encapsulated curcumin ("nanocurcumin"): a novel strategy for human cancer therapy. J. Nanobiotechnol. 5(3), 1-18 (2007).
    • (2007) J. Nanobiotechnol. , vol.5 , Issue.3 , pp. 1-18
    • Bisht, S.1    Feldmann, G.2    Soni, S.3
  • 101
    • 79952341098 scopus 로고    scopus 로고
    • A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors
    • Lim KJ, Bisht S, Bar EE, Maitra A, Eberhart CG. A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors. Cancer Biol. Ther. 11(5), 464-473 (2011).
    • (2011) Cancer Biol. Ther. , vol.11 , Issue.5 , pp. 464-473
    • Lim, K.J.1    Bisht, S.2    Bar, E.E.3    Maitra, A.4    Eberhart, C.G.5
  • 102
    • 80055109899 scopus 로고    scopus 로고
    • Mitochondrial targeting liposomes incorporating daunorubicin and quinacrine for treatment of relapsed breast cancer arising from cancer stem cells
    • Zhang L, Yao H-J, Yu Y et al. Mitochondrial targeting liposomes incorporating daunorubicin and quinacrine for treatment of relapsed breast cancer arising from cancer stem cells. Biomaterials 33(2), 565-582 (2012).
    • (2012) Biomaterials , vol.33 , Issue.2 , pp. 565-582
    • Zhang, L.1    Yao, H.-J.2    Yu, Y.3
  • 103
    • 84884901283 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate attenuates head and neck cancer stem cell traits through suppression of Notch pathway
    • Lee SH, Nam HJ, Kang HJ, Kwon HW, Lim YC. Epigallocatechin-3-gallate attenuates head and neck cancer stem cell traits through suppression of Notch pathway. Eur. J. Cancer 49(15), 3210-3218 (2013).
    • (2013) Eur. J. Cancer , vol.49 , Issue.15 , pp. 3210-3218
    • Lee, S.H.1    Nam, H.J.2    Kang, H.J.3    Kwon, H.W.4    Lim, Y.C.5
  • 104
    • 35348837163 scopus 로고    scopus 로고
    • Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma
    • Bar EE, Chaudhry A, Lin A et al. Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma. Stem Cells 25(10), 2524-2533 (2007).
    • (2007) Stem Cells , vol.25 , Issue.10 , pp. 2524-2533
    • Bar, E.E.1    Chaudhry, A.2    Lin, A.3
  • 105
    • 69249156565 scopus 로고    scopus 로고
    • Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer
    • Mueller MT, Hermann PC, Witthauer J et al. Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer. Gastroenterology 137(3), 1102-1113 (2009).
    • (2009) Gastroenterology , vol.137 , Issue.3 , pp. 1102-1113
    • Mueller, M.T.1    Hermann, P.C.2    Witthauer, J.3
  • 106
    • 84875131206 scopus 로고    scopus 로고
    • A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition
    • Goff DJ, Recart AC, Sadarangani A et al. A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. Cell Stem Cell 12(3), 316-328 (2013).
    • (2013) Cell Stem Cell , vol.12 , Issue.3 , pp. 316-328
    • Goff, D.J.1    Recart, A.C.2    Sadarangani, A.3
  • 107
    • 84887296747 scopus 로고    scopus 로고
    • Phenformin enhances the therapeutic benefit of BRAFV600E inhibition in melanoma
    • Yuan P, Ito K, Perez-Lorenzo R et al. Phenformin enhances the therapeutic benefit of BRAFV600E inhibition in melanoma. Proc. Natl Acad. Sci. USA 110(45), 18226-18231 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , Issue.45 , pp. 18226-18231
    • Yuan, P.1    Ito, K.2    Perez-Lorenzo, R.3
  • 108
    • 84855181703 scopus 로고    scopus 로고
    • The cancer stem cell antigens CD133, BCRP1/ABCG2 and CD117/c-KIT are not associated with prognosis in resected early-stage non-small cell lung cancer
    • Herpel E, Jensen K, Muley T et al. The cancer stem cell antigens CD133, BCRP1/ABCG2 and CD117/c-KIT are not associated with prognosis in resected early-stage non-small cell lung cancer. Anticancer Res. 31(12), 4491-4500 (2011).
    • (2011) Anticancer Res. , vol.31 , Issue.12 , pp. 4491-4500
    • Herpel, E.1    Jensen, K.2    Muley, T.3
  • 109
    • 84655175065 scopus 로고    scopus 로고
    • The combination of stem cell markers CD133 and ABCG2 predicts relapse in stage i non-small cell lung carcinomas
    • Li F, Zeng H, Ying K. The combination of stem cell markers CD133 and ABCG2 predicts relapse in stage I non-small cell lung carcinomas. Med. Oncol. 28(4), 1458-1462 (2011).
    • (2011) Med. Oncol. , vol.28 , Issue.4 , pp. 1458-1462
    • Li, F.1    Zeng, H.2    Ying, K.3
  • 110
    • 77957591579 scopus 로고    scopus 로고
    • Targeting breast cancer stem cells
    • Liu S, Wicha MS. Targeting breast cancer stem cells. J. Clin. Oncol. 28(25), 4006-4012 (2010).
    • (2010) J. Clin. Oncol. , vol.28 , Issue.25 , pp. 4006-4012
    • Liu, S.1    Wicha, M.S.2
  • 111
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype
    • Zhou S, Schuetz JD, Bunting KD et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype. Nat. Med. 7(9), 1028-1034 (2001).
    • (2001) Nat. Med. , vol.7 , Issue.9 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3
  • 112
    • 0037386583 scopus 로고    scopus 로고
    • Breast cancer stem cells revealed
    • Dick JE. Breast cancer stem cells revealed. Proc. Natl Acad. Sci. USA 100(7), 3547-3549 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.7 , pp. 3547-3549
    • Dick, J.E.1
  • 113
    • 38349165576 scopus 로고    scopus 로고
    • Identification of cells initiating human melanomas
    • Schatton T, Murphy GF, Frank NY et al. Identification of cells initiating human melanomas. Nature 451(7176), 345-349 (2008).
    • (2008) Nature , vol.451 , Issue.7176 , pp. 345-349
    • Schatton, T.1    Murphy, G.F.2    Frank, N.Y.3
  • 114
    • 84883219941 scopus 로고    scopus 로고
    • Functional features of cancer stem cells in melanoma cell lines
    • Zimmerer RM, Korn P, Demougin P et al. Functional features of cancer stem cells in melanoma cell lines. Cancer Cell Int. 13(1), 78 (2013).
    • (2013) Cancer Cell Int. , vol.13 , Issue.1 , pp. 78
    • Zimmerer, R.M.1    Korn, P.2    Demougin, P.3
  • 115
    • 79954617310 scopus 로고    scopus 로고
    • Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth
    • Civenni G, Walter A, Kobert N et al. Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth. Cancer Res. 71(8), 3098-3109 (2011).
    • (2011) Cancer Res. , vol.71 , Issue.8 , pp. 3098-3109
    • Civenni, G.1    Walter, A.2    Kobert, N.3
  • 116
    • 84870366361 scopus 로고    scopus 로고
    • Expressions of putative cancer stem cell markers ABCB1, ABCG2, and CD133 are correlated with the degree of differentiation of gastric cancer
    • Jiang Y, He Y, Li H et al. Expressions of putative cancer stem cell markers ABCB1, ABCG2, and CD133 are correlated with the degree of differentiation of gastric cancer. Gastric Cancer 15(4), 440-450 (2012).
    • (2012) Gastric Cancer , vol.15 , Issue.4 , pp. 440-450
    • Jiang, Y.1    He, Y.2    Li, H.3
  • 117
    • 84856963775 scopus 로고    scopus 로고
    • Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype
    • Jiang J, Zhang Y, Chuai S et al. Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype. Oncogene 31(6), 671-682 (2012).
    • (2012) Oncogene , vol.31 , Issue.6 , pp. 671-682
    • Jiang, J.1    Zhang, Y.2    Chuai, S.3
  • 118
  • 120
    • 34547415968 scopus 로고    scopus 로고
    • CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia
    • Hosen N, Park CY, Tatsumi N et al. CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia. Proc. Natl Acad. Sci. USA 104(26), 11008-11013 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.26 , pp. 11008-11013
    • Hosen, N.1    Park, C.Y.2    Tatsumi, N.3
  • 121
    • 24344506258 scopus 로고    scopus 로고
    • Cancer stem cells: Lessons from leukemia
    • Wang JC, Dick JE. Cancer stem cells: lessons from leukemia. Trends Cell Biol. 15(9), 494-501 (2005).
    • (2005) Trends Cell Biol. , vol.15 , Issue.9 , pp. 494-501
    • Wang, J.C.1    Dick, J.E.2
  • 122
    • 67649200331 scopus 로고    scopus 로고
    • Monoclonal antibody-mediated targeting of CD123, IL-3 receptor - Chain, eliminates human acute myeloid leukemic stem cells
    • Jin L, Lee EM, Ramshaw HS et al. Monoclonal antibody-mediated targeting of CD123, IL-3 receptor - chain, eliminates human acute myeloid leukemic stem cells. Cell Stem Cell 5(1), 31-42 (2009).
    • (2009) Cell Stem Cell , vol.5 , Issue.1 , pp. 31-42
    • Jin, L.1    Lee, E.M.2    Ramshaw, H.S.3
  • 123
    • 45549100014 scopus 로고    scopus 로고
    • Pancreatic cancer stem cells
    • Lee CJ, Dosch J, Simeone DM. Pancreatic cancer stem cells. J. Clin. Oncol. 26(17), 2806-2812 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.17 , pp. 2806-2812
    • Lee, C.J.1    Dosch, J.2    Simeone, D.M.3
  • 124
    • 79955764915 scopus 로고    scopus 로고
    • Novel therapeutic strategies for targeting liver cancer stem cells
    • Oishi N, Wang XW. Novel therapeutic strategies for targeting liver cancer stem cells. Int. J. Biol. Sci. 7(5), 517-535 (2011).
    • (2011) Int. J. Biol. Sci. , vol.7 , Issue.5 , pp. 517-535
    • Oishi, N.1    Wang, X.W.2
  • 125
    • 84877156945 scopus 로고    scopus 로고
    • Cancer stem cells in the development of liver cancer
    • Yamashita T, Wang XW. Cancer stem cells in the development of liver cancer. J. Clin. Invest. 123(5), 1911-1918 (2013).
    • (2013) J. Clin. Invest. , vol.123 , Issue.5 , pp. 1911-1918
    • Yamashita, T.1    Wang, X.W.2
  • 127
    • 77049103045 scopus 로고    scopus 로고
    • Brain tumor stem-like cells identified by neural stem cell marker CD15
    • Mao X-G, Zhang X, Xue X-Y et al. Brain tumor stem-like cells identified by neural stem cell marker CD15. Transl. Oncol. 2(4), 247 (2009).
    • (2009) Transl. Oncol. , vol.2 , Issue.4 , pp. 247
    • Mao, X.-G.1    Zhang, X.2    Xue, X.-Y.3
  • 128
    • 72449210651 scopus 로고    scopus 로고
    • Cancer stem cells: Cell culture, markers, and targets for new therapies
    • Gilbert CA, Ross AH. Cancer stem cells: cell culture, markers, and targets for new therapies. J. Cell. Biochem. 108(5), 1031-1038 (2009).
    • (2009) J. Cell. Biochem. , vol.108 , Issue.5 , pp. 1031-1038
    • Gilbert, C.A.1    Ross, A.H.2
  • 129
    • 48249150771 scopus 로고    scopus 로고
    • Bladder cancer initiating cells (BCICs) are among EMA-CD44v6+ subset: Novel methods for isolating undetermined cancer stem (initiating) cells
    • Yang Y, Chang J. Bladder cancer initiating cells (BCICs) are among EMA-CD44v6+ subset: novel methods for isolating undetermined cancer stem (initiating) cells. Cancer Invest. 26(7), 725-733 (2008).
    • (2008) Cancer Invest. , vol.26 , Issue.7 , pp. 725-733
    • Yang, Y.1    Chang, J.2
  • 130
    • 85015510681 scopus 로고    scopus 로고
    • Cancer stem cell-like characteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line
    • Huang P, Watanabe M, Kaku H et al. Cancer stem cell-like characteristics of a CD133+ subpopulation in the J82 human bladder cancer cell line. Mol. Clin. Oncol. 1(1), 180-184 (2013).
    • (2013) Mol. Clin. Oncol. , vol.1 , Issue.1 , pp. 180-184
    • Huang, P.1    Watanabe, M.2    Kaku, H.3
  • 132
    • 79957917044 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival
    • Silva IA, Bai S, Mclean K et al. Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival. Cancer Res. 71(11), 3991-4001 (2011).
    • (2011) Cancer Res. , vol.71 , Issue.11 , pp. 3991-4001
    • Silva, I.A.1    Bai, S.2    McLean, K.3
  • 133
    • 79951825513 scopus 로고    scopus 로고
    • Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2
    • Rizzo S, Hersey JM, Mellor P et al. Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2. Mol. Cancer Ther. 10(2), 325-335 (2011).
    • (2011) Mol. Cancer Ther. , vol.10 , Issue.2 , pp. 325-335
    • Rizzo, S.1    Hersey, J.M.2    Mellor, P.3
  • 134
    • 33646906851 scopus 로고    scopus 로고
    • Prostate cancer stem cells
    • Collins AT, Maitland NJ. Prostate cancer stem cells. Eur. J. Cancer 42(9), 1213-1218 (2006).
    • (2006) Eur. J. Cancer , vol.42 , Issue.9 , pp. 1213-1218
    • Collins, A.T.1    Maitland, N.J.2
  • 135
    • 58449089751 scopus 로고    scopus 로고
    • Prostate cancer stem cells
    • Lang S, Frame F, Collins A. Prostate cancer stem cells. J. Pathol. 217(2), 299-306 (2009).
    • (2009) J. Pathol. , vol.217 , Issue.2 , pp. 299-306
    • Lang, S.1    Frame, F.2    Collins, A.3
  • 136
    • 39449088496 scopus 로고    scopus 로고
    • Identification and expansion of the tumorigenic lung cancer stem cell population
    • Eramo A, Lotti F, Sette G et al. Identification and expansion of the tumorigenic lung cancer stem cell population. Cell Death Differ. 15(3), 504-514 (2008).
    • (2008) Cell Death Differ. , vol.15 , Issue.3 , pp. 504-514
    • Eramo, A.1    Lotti, F.2    Sette, G.3
  • 137
    • 70449717534 scopus 로고    scopus 로고
    • Cancer stem cells in head and neck squamous cell carcinoma
    • Ailles L, Prince M. Cancer stem cells in head and neck squamous cell carcinoma. Cancer Stem Cells 175-193 (2009).
    • (2009) Cancer Stem Cells , pp. 175-193
    • Ailles, L.1    Prince, M.2
  • 138
    • 84859045046 scopus 로고    scopus 로고
    • Head and neck cancer stem cells
    • Krishnamurthy S, Nör J. Head and neck cancer stem cells. J. Dent. Res. 91(4), 334-340 (2012).
    • (2012) J. Dent. Res. , vol.91 , Issue.4 , pp. 334-340
    • Krishnamurthy, S.1    Nör, J.2
  • 139
    • 33846512398 scopus 로고    scopus 로고
    • Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
    • Prince M, Sivanandan R, Kaczorowski A et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc. Natl Acad. Sci. USA 104(3), 973-978 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.3 , pp. 973-978
    • Prince, M.1    Sivanandan, R.2    Kaczorowski, A.3
  • 140
    • 70449366086 scopus 로고    scopus 로고
    • Identification and characterization of cancer stem-like cells from primary carcinoma of the cervix uteri
    • Feng D, Peng C, Li C et al. Identification and characterization of cancer stem-like cells from primary carcinoma of the cervix uteri. Oncol. Rep. 22(5), 1129-1134 (2009).
    • (2009) Oncol. Rep. , vol.22 , Issue.5 , pp. 1129-1134
    • Feng, D.1    Peng, C.2    Li, C.3
  • 141
    • 84865109716 scopus 로고    scopus 로고
    • Isolation and characterization of cancer stem cells from cervical cancer HeLa cells
    • Zhang S-L, Wang Y-S, Zhou T, Yu X-W, Wei Z-T, Li Y-L. Isolation and characterization of cancer stem cells from cervical cancer HeLa cells. Cytotechnology 64(4), 477-484 (2012).
    • (2012) Cytotechnology , vol.64 , Issue.4 , pp. 477-484
    • Zhang, S.-L.1    Wang, Y.-S.2    Zhou, T.3    Yu, X.-W.4    Wei, Z.-T.5    Li, Y.-L.6
  • 142
    • 84892932353 scopus 로고    scopus 로고
    • Anticancer bioactive peptide-3 inhibits human gastric cancer growth by suppressing gastric cancer stem cells
    • Yu L, Yang L, An W, Su X. Anticancer bioactive peptide-3 inhibits human gastric cancer growth by suppressing gastric cancer stem cells. J. Cell. Biochem. 115(4), 697-711 (2014).
    • (2014) J. Cell. Biochem. , vol.115 , Issue.4 , pp. 697-711
    • Yu, L.1    Yang, L.2    An, W.3    Su, X.4
  • 143
    • 84872414706 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition and cancer stem cell phenotypes leading to liver metastasis are abrogated by the novel TGF-1-targeting peptides P17 and P144
    • Zubeldia IG, Bleau A-M, Redrado M et al. Epithelial to mesenchymal transition and cancer stem cell phenotypes leading to liver metastasis are abrogated by the novel TGF-1-targeting peptides P17 and P144. Exp. Cell. Res. 319(3), 12-22 (2013).
    • (2013) Exp. Cell. Res. , vol.319 , Issue.3 , pp. 12-22
    • Zubeldia, I.G.1    Bleau, A.-M.2    Redrado, M.3


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