Drug Screening Identifies Niclosamide as an Inhibitor of Breast Cancer Stem-Like Cells

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Wang, Yu Chi ^a,b   Chao, Tai Kuang ^b   Chang, Cheng Chang ^a,b   Yo, Yi Te ^a   Yu, Mu Hsien ^a,b   Lai, Hung Cheng ^a,b  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; BREFELDIN A; CD24 ANTIGEN; CELL SURFACE MARKER; HERMES ANTIGEN; MESSENGER RNA; NICLOSAMIDE; OCTAMER TRANSCRIPTION FACTOR 4; OUABAIN; PACLITAXEL; PARTHENOLIDE; RETINOIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER STEM CELL; CARCINOGENICITY; CELL ASSAY; CELL ISOLATION; CELL STRAIN MCF 7; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG SCREENING; DRUG TARGETING; DYE EXCLUSION METHOD; FEMALE; FLOW CYTOMETRY; GENE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOLATION PROCEDURE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIDE POPULATION CELL; SIDE POPULATION SPHERE CELL; SIGNAL TRANSDUCTION; STEMNESS GENE; TREATMENT DURATION; TUMOR SPHEROID;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SEPARATION; DRUG EVALUATION, PRECLINICAL; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MICE; MICE, SCID; NEOPLASTIC STEM CELLS; NICLOSAMIDE; SIDE-POPULATION CELLS; SIGNAL TRANSDUCTION; SMALL MOLECULE LIBRARIES; SPHEROIDS, CELLULAR;

EID: 84884235663     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074538     Document Type: Article

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