-
1
-
-
0022891340
-
Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
PMID: 3537791
-
Dvorak HF . Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 1986; 315: 1650-1659 [PMID: 3537791 DOI: 10.1056/NEJM198612253152606]
-
(1986)
N Engl J Med
, vol.315
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
2
-
-
0037805549
-
Basement membranes: Structure, assembly and role in tumour angiogenesis
-
PMID: 12778132
-
Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer 2003; 3: 422-433 [PMID: 12778132 DOI: 10.1038/nrc1094]
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 422-433
-
-
Kalluri, R.1
-
3
-
-
41749116607
-
Cancer biology. All in the stroma: Cancer's Cosa Nostra
-
PMID: 18388269
-
Marx J. Cancer biology. All in the stroma: cancer's Cosa Nostra. Science 2008; 320: 38-41 [PMID: 18388269 DOI: 10.1126/ science.320.5872.38]
-
(2008)
Science
, vol.320
, pp. 38-41
-
-
Marx, J.1
-
4
-
-
76349096670
-
Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-kappaB-dependent manner
-
PMID: 20138012
-
Erez N, Truitt M, Olson P, Arron ST, Hanahan D. Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner. Cancer Cell 2010; 17: 135-147 [PMID: 20138012 DOI: 10.1016/j.ccr.2009.12.041]
-
(2010)
Cancer Cell
, vol.17
, pp. 135-147
-
-
Erez, N.1
Truitt, M.2
Olson, P.3
Arron, S.T.4
Hanahan, D.5
-
5
-
-
38849141696
-
Cancerassociated stromal fibroblasts promote pancreatic tumor progression
-
PMID: 18245495
-
Hwang RF, Moore T, Arumugam T, Ramachandran V, Amos KD, Rivera A, Ji B, Evans DB, Logsdon CD. Cancerassociated stromal fibroblasts promote pancreatic tumor progression. Cancer Res 2008; 68: 918-926 [PMID: 18245495 DOI: 10.1158/0008-5472.CAN-07-5714]
-
(2008)
Cancer Res
, vol.68
, pp. 918-926
-
-
Hwang, R.F.1
Moore, T.2
Arumugam, T.3
Ramachandran, V.4
Amos, K.D.5
Rivera, A.6
Ji, B.7
Evans, D.B.8
Logsdon, C.D.9
-
6
-
-
60949101225
-
Cancer-associated fibroblasts and tumor growth-bystanders turning into key players
-
PMID: 19211240
-
Ostman A, Augsten M. Cancer-associated fibroblasts and tumor growth-bystanders turning into key players. Curr Opin Genet Dev 2009; 19: 67-73 [PMID: 19211240 DOI: 10.1016/ j.gde.2009.01.003]
-
(2009)
Curr Opin Genet Dev
, vol.19
, pp. 67-73
-
-
Ostman, A.1
Augsten, M.2
-
7
-
-
14644404221
-
A stromal address code defined by fibroblasts
-
PMID: 15745857
-
Parsonage G, Filer AD, Haworth O, Nash GB, Rainger GE, Salmon M, Buckley CD. A stromal address code defined by fibroblasts. Trends Immunol 2005; 26: 150-156 [PMID: 15745857 DOI: 10.1016/j.it.2004.11.014]
-
(2005)
Trends Immunol
, vol.26
, pp. 150-156
-
-
Parsonage, G.1
Filer, A.D.2
Haworth, O.3
Nash, G.B.4
Rainger, G.E.5
Salmon, M.6
Buckley, C.D.7
-
8
-
-
75849154010
-
Cancer associated fibroblasts in cancer pathogenesis
-
PMID: 19896548
-
Franco OE, Shaw AK, Strand DW, Hayward SW. Cancer associated fibroblasts in cancer pathogenesis. Semin Cell Dev Biol 2010; 21: 33-39 [PMID: 19896548 DOI: 10.1016/j.semcdb.2009.10.010]
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 33-39
-
-
Franco, O.E.1
Shaw, A.K.2
Strand, D.W.3
Hayward, S.W.4
-
9
-
-
33646384428
-
Fibroblasts in cancer
-
PMID: 16572188
-
Kalluri R, Zeisberg M. Fibroblasts in cancer. Nat Rev Cancer 2006; 6: 392-401 [PMID: 16572188 DOI: 10.1038/nrc1877]
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 392-401
-
-
Kalluri, R.1
Zeisberg, M.2
-
10
-
-
77955605521
-
Cancer-associated fibroblasts and epithelial-mesenchymal transition in metastatic oral tongue squamous cell carcinoma
-
PMID: 20340130
-
Vered M, Dayan D, Yahalom R, Dobriyan A, Barshack I, Bello IO, Kantola S, Salo T. Cancer-associated fibroblasts and epithelial-mesenchymal transition in metastatic oral tongue squamous cell carcinoma. Int J Cancer 2010; 127: 1356-1362 [PMID: 20340130 DOI: 10.1002/ijc.25358]
-
(2010)
Int J Cancer
, vol.127
, pp. 1356-1362
-
-
Vered, M.1
Dayan, D.2
Yahalom, R.3
Dobriyan, A.4
Barshack, I.5
Bello, I.O.6
Kantola, S.7
Salo, T.8
-
11
-
-
0036277026
-
Myofibroblasts and mechano-regulation of connective tissue remodelling
-
PMID: 11988769
-
Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol 2002; 3: 349-363 [PMID: 11988769 DOI: 10.1038/nrm809]
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 349-363
-
-
Tomasek, J.J.1
Gabbiani, G.2
Hinz, B.3
Chaponnier, C.4
Brown, R.A.5
-
12
-
-
0037899249
-
The myofibroblast in wound healing and fibrocontractive diseases
-
PMID: 12845617
-
Gabbiani G. The myofibroblast in wound healing and fibrocontractive diseases. J Pathol 2003; 200: 500-503 [PMID: 12845617 DOI: 10.1002/path.1427]
-
(2003)
J Pathol
, vol.200
, pp. 500-503
-
-
Gabbiani, G.1
-
13
-
-
3843069939
-
FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor
-
PMID: 15133496
-
Ramirez-Montagut T, Blachere NE, Sviderskaya EV, Bennett DC, Rettig WJ, Garin-Chesa P, Houghton AN. FAPalpha, a surface peptidase expressed during wound healing, is a tumor suppressor. Oncogene 2004; 23: 5435-5446 [PMID: 15133496 DOI: 10.1038/sj.onc.1207730]
-
(2004)
Oncogene
, vol.23
, pp. 5435-5446
-
-
Ramirez-Montagut, T.1
Blachere, N.E.2
Sviderskaya, E.V.3
Bennett, D.C.4
Rettig, W.J.5
Garin-Chesa, P.6
Houghton, A.N.7
-
14
-
-
77957870040
-
Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial-mesenchymal tran-sition-like state in breast cancer cells in vitro
-
PMID: 20841377
-
Gao MQ, Kim BG, Kang S, Choi YP, Park H, Kang KS, Cho NH. Stromal fibroblasts from the interface zone of human breast carcinomas induce an epithelial-mesenchymal tran-sition-like state in breast cancer cells in vitro. J Cell Sci 2010; 123: 3507-3514 [PMID: 20841377 DOI: 10.1242/jcs.072900]
-
(2010)
J Cell Sci
, vol.123
, pp. 3507-3514
-
-
Gao, M.Q.1
Kim, B.G.2
Kang, S.3
Choi, Y.P.4
Park, H.5
Kang, K.S.6
Cho, N.H.7
-
15
-
-
77956280130
-
Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness
-
PMID: 20699369
-
Giannoni E, Bianchini F, Masieri L, Serni S, Torre E, Calorini L, Chiarugi P. Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness. Cancer Res 2010; 70: 6945-6956 [PMID: 20699369 DOI: 10.1158/0008-5472.CAN-10-0785]
-
(2010)
Cancer Res
, vol.70
, pp. 6945-6956
-
-
Giannoni, E.1
Bianchini, F.2
Masieri, L.3
Serni, S.4
Torre, E.5
Calorini, L.6
Chiarugi, P.7
-
16
-
-
80052032390
-
Tumor-secreted lysophostatidic acid accelerates hepatocellular carcinoma progression by promoting differentiation of peritumoral fibroblasts in myofibroblasts
-
PMID: 21674557
-
Mazzocca A, Dituri F, Lupo L, Quaranta M, Antonaci S, Giannelli G. Tumor-secreted lysophostatidic acid accelerates hepatocellular carcinoma progression by promoting differentiation of peritumoral fibroblasts in myofibroblasts. Hepatology 2011; 54: 920-930 [PMID: 21674557 DOI: 10.1002/hep.24485]
-
(2011)
Hepatology
, vol.54
, pp. 920-930
-
-
Mazzocca, A.1
Dituri, F.2
Lupo, L.3
Quaranta, M.4
Antonaci, S.5
Giannelli, G.6
-
17
-
-
57149111920
-
Global hypomethylation of genomic DNA in cancer-associated myofibroblasts
-
PMID: 19047171
-
Jiang L, Gonda TA, Gamble MV, Salas M, Seshan V, Tu S, Twaddell WS, Hegyi P, Lazar G, Steele I, Varro A, Wang TC, Tycko B. Global hypomethylation of genomic DNA in cancer-associated myofibroblasts. Cancer Res 2008; 68: 9900-9908 [PMID: 19047171 DOI: 10.1158/0008-5472.CAN-08-1319]
-
(2008)
Cancer Res
, vol.68
, pp. 9900-9908
-
-
Jiang, L.1
Gonda, T.A.2
Gamble, M.V.3
Salas, M.4
Seshan, V.5
Tu, S.6
Twaddell, W.S.7
Hegyi, P.8
Lazar, G.9
Steele, I.10
Varro, A.11
Wang, T.C.12
Tycko, B.13
-
18
-
-
0038676258
-
Regulation of wound healing by growth factors and cytokines
-
PMID: 12843410
-
Werner S, Grose R. Regulation of wound healing by growth factors and cytokines. Physiol Rev 2003; 83: 835-870 [PMID: 12843410 DOI: 10.1152/physrev.00031.2002]
-
(2003)
Physiol Rev
, vol.83
, pp. 835-870
-
-
Werner, S.1
Grose, R.2
-
19
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
PMID: 12778130
-
Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003; 3: 401-410 [PMID: 12778130 DOI: 10.1038/nrc1093]
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
20
-
-
70350510924
-
Pten in stromal fibroblasts suppresses mammary epithelial tumours
-
PMID: 19847259
-
Trimboli AJ, Cantemir-Stone CZ, Li F, Wallace JA, Merchant A, Creasap N, Thompson JC, Caserta E, Wang H, Chong JL, Naidu S, Wei G, Sharma SM, Stephens JA, Fernandez SA, Gurcan MN, Weinstein MB, Barsky SH, Yee L, Rosol TJ, Stromberg PC, Robinson ML, Pepin F, Hallett M, Park M, Ostrowski MC, Leone G. Pten in stromal fibroblasts suppresses mammary epithelial tumours. Nature 2009; 461: 1084-1091 [PMID: 19847259 DOI: 10.1038/nature08486]
-
(2009)
Nature
, vol.461
, pp. 1084-1091
-
-
Trimboli, A.J.1
Cantemir-Stone, C.Z.2
Li, F.3
Wallace, J.A.4
Merchant, A.5
Creasap, N.6
Thompson, J.C.7
Caserta, E.8
Wang, H.9
Chong, J.L.10
Naidu, S.11
Wei, G.12
Sharma, S.M.13
Stephens, J.A.14
Fernandez, S.A.15
Gurcan, M.N.16
Weinstein, M.B.17
Barsky, S.H.18
Yee, L.19
Rosol, T.J.20
Stromberg, P.C.21
Robinson, M.L.22
Pepin, F.23
Hallett, M.24
Park, M.25
Ostrowski, M.C.26
Leone, G.27
more..
-
21
-
-
61449187403
-
Origin of carcinoma associated fibroblasts
-
PMID: 19182519
-
Haviv I, Polyak K, Qiu W, Hu M, Campbell I. Origin of carcinoma associated fibroblasts. Cell Cycle 2009; 8: 589-595 [PMID: 19182519]
-
(2009)
Cell Cycle
, vol.8
, pp. 589-595
-
-
Haviv, I.1
Polyak, K.2
Qiu, W.3
Hu, M.4
Campbell, I.5
-
22
-
-
36349034540
-
Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment
-
PMID: 17916596
-
Mueller L, Goumas FA, Affeldt M, Sandtner S, Gehling UM, Brilloff S, Walter J, Karnatz N, Lamszus K, Rogiers X, Broering DC. Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment. Am J Pathol 2007; 171: 1608-1618 [PMID: 17916596 DOI: 10.2353/ajpath.2007.060661]
-
(2007)
Am J Pathol
, vol.171
, pp. 1608-1618
-
-
Mueller, L.1
Goumas, F.A.2
Affeldt, M.3
Sandtner, S.4
Gehling, U.M.5
Brilloff, S.6
Walter, J.7
Karnatz, N.8
Lamszus, K.9
Rogiers, X.10
Broering, D.C.11
-
23
-
-
4644349674
-
Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease
-
PMID: 15466389
-
Steiling H, Mühlbauer M, Bataille F, Schölmerich J, Werner S, Hellerbrand C. Activated hepatic stellate cells express keratinocyte growth factor in chronic liver disease. Am J Pathol 2004; 165: 1233-1241 [PMID: 15466389 DOI: 10.1016/S0002-9440(10)63383-4]
-
(2004)
Am J Pathol
, vol.165
, pp. 1233-1241
-
-
Steiling, H.1
Mühlbauer, M.2
Bataille, F.3
Schölmerich, J.4
Werner, S.5
Hellerbrand, C.6
-
24
-
-
78650563018
-
Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumorpromoting mammary stromal myofibroblasts
-
PMID: 21041659
-
Kojima Y, Acar A, Eaton EN, Mellody KT, Scheel C, Ben-Porath I, Onder TT, Wang ZC, Richardson AL, Weinberg RA, Orimo A. Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumorpromoting mammary stromal myofibroblasts. Proc Natl Acad Sci USA 2010; 107: 20009-20014 [PMID: 21041659 DOI: 10.1073/pnas.1013805107]
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20009-20014
-
-
Kojima, Y.1
Acar, A.2
Eaton, E.N.3
Mellody, K.T.4
Scheel, C.5
Ben-Porath, I.6
Onder, T.T.7
Wang, Z.C.8
Richardson, A.L.9
Weinberg, R.A.10
Orimo, A.11
-
25
-
-
79751501829
-
Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth
-
PMID: 21316604
-
Quante M, Tu SP, Tomita H, Gonda T, Wang SS, Takashi S, Baik GH, Shibata W, Diprete B, Betz KS, Friedman R, Varro A, Tycko B, Wang TC. Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer Cell 2011; 19: 257-272 [PMID: 21316604 DOI: 10.1016/j.ccr.2011.01.020]
-
(2011)
Cancer Cell
, vol.19
, pp. 257-272
-
-
Quante, M.1
Tu, S.P.2
Tomita, H.3
Gonda, T.4
Wang, S.S.5
Takashi, S.6
Baik, G.H.7
Shibata, W.8
Diprete, B.9
Betz, K.S.10
Friedman, R.11
Varro, A.12
Tycko, B.13
Wang, T.C.14
-
26
-
-
49249120549
-
Carcinomaassociated fibroblast-like differentiation of human mesenchymal stem cells
-
PMID: 18519693
-
Mishra PJ, Mishra PJ, Humeniuk R, Medina DJ, Alexe G, Mesirov JP, Ganesan S, Glod JW, Banerjee D. Carcinomaassociated fibroblast-like differentiation of human mesenchymal stem cells. Cancer Res 2008; 68: 4331-4339 [PMID: 18519693 DOI: 10.1158/0008-5472.CAN-08-0943]
-
(2008)
Cancer Res
, vol.68
, pp. 4331-4339
-
-
Mishra, P.J.1
Mishra, P.J.2
Humeniuk, R.3
Medina, D.J.4
Alexe, G.5
Mesirov, J.P.6
Ganesan, S.7
Glod, J.W.8
Banerjee, D.9
-
27
-
-
35948945337
-
Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts
-
PMID: 17974953
-
Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Res 2007; 67: 10123-10128 [PMID: 17974953 DOI: 10.1158/0008-5472.CAN-07-3127]
-
(2007)
Cancer Res
, vol.67
, pp. 10123-10128
-
-
Zeisberg, E.M.1
Potenta, S.2
Xie, L.3
Zeisberg, M.4
Kalluri, R.5
-
28
-
-
42549152045
-
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
-
PMID: 18408720
-
Qiu W, Hu M, Sridhar A, Opeskin K, Fox S, Shipitsin M, Trivett M, Thompson ER, Ramakrishna M, Gorringe KL, Polyak K, Haviv I, Campbell IG. No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas. Nat Genet 2008; 40: 650-655 [PMID: 18408720 DOI: 10.1038/ng.117]
-
(2008)
Nat Genet
, vol.40
, pp. 650-655
-
-
Qiu, W.1
Hu, M.2
Sridhar, A.3
Opeskin, K.4
Fox, S.5
Shipitsin, M.6
Trivett, M.7
Thompson, E.R.8
Ramakrishna, M.9
Gorringe, K.L.10
Polyak, K.11
Haviv, I.12
Campbell, I.G.13
-
29
-
-
0028890174
-
The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells
-
PMID: 7532191
-
Ronnov-Jessen L, Petersen OW, Koteliansky VE, Bissell MJ. The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells. J Clin Invest 1995; 95: 859-873 [PMID: 7532191 DOI: 10.1172/JCI117736]
-
(1995)
J Clin Invest
, vol.95
, pp. 859-873
-
-
Ronnov-Jessen, L.1
Petersen, O.W.2
Koteliansky, V.E.3
Bissell, M.J.4
-
30
-
-
0035902141
-
The microenvironment of the tumourhost interface
-
PMID: 11357145
-
Liotta LA, Kohn EC. The microenvironment of the tumourhost interface. Nature 2001; 411: 375-379 [PMID: 11357145 DOI: 10.1038/35077241]
-
(2001)
Nature
, vol.411
, pp. 375-379
-
-
Liotta, L.A.1
Kohn, E.C.2
-
31
-
-
0022457283
-
Occurrence of a fetal fibroblast phenotype in familial breast cancer
-
PMID: 3710614
-
Schor SL, Haggie JA, Durning P, Howell A, Smith L, Sellwood RA, Crowther D. Occurrence of a fetal fibroblast phenotype in familial breast cancer. Int J Cancer 1986; 37: 831-836 [PMID: 3710614]
-
(1986)
Int J Cancer
, vol.37
, pp. 831-836
-
-
Schor, S.L.1
Haggie, J.A.2
Durning, P.3
Howell, A.4
Smith, L.5
Sellwood, R.A.6
Crowther, D.7
-
32
-
-
0033215242
-
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium
-
PMID: 10519415
-
Olumi AF, Grossfeld GD, Hayward SW, Carroll PR, Tlsty TD, Cunha GR. Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium. Cancer Res 1999; 59: 5002-5011 [PMID: 10519415]
-
(1999)
Cancer Res
, vol.59
, pp. 5002-5011
-
-
Olumi, A.F.1
Grossfeld, G.D.2
Hayward, S.W.3
Carroll, P.R.4
Tlsty, T.D.5
Cunha, G.R.6
-
33
-
-
57349113716
-
Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis
-
PMID: 18767044
-
Giulianelli S, Cerliani JP, Lamb CA, Fabris VT, Bottino MC, Gorostiaga MA, Novaro V, Góngora A, Baldi A, Molinolo A, Lanari C. Carcinoma-associated fibroblasts activate progesterone receptors and induce hormone independent mammary tumor growth: A role for the FGF-2/FGFR-2 axis. Int J Cancer 2008; 123: 2518-2531 [PMID: 18767044 DOI: 10.1002/ijc.23802]
-
(2008)
Int J Cancer
, vol.123
, pp. 2518-2531
-
-
Giulianelli, S.1
Cerliani, J.P.2
Lamb, C.A.3
Fabris, V.T.4
Bottino, M.C.5
Gorostiaga, M.A.6
Novaro, V.7
Góngora, A.8
Baldi, A.9
Molinolo, A.10
Lanari, C.11
-
34
-
-
80655149144
-
Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/β-catenin signalling pathway
-
PMID: 21672941
-
Fu L, Zhang C, Zhang LY, Dong SS, Lu LH, Chen J, Dai Y, Li Y, Kong KL, Kwong DL, Guan XY. Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/β-catenin signalling pathway. Gut 2011; 60: 1635-1643 [PMID: 21672941 DOI: 10.1136/gut.2011.241638]
-
(2011)
Gut
, vol.60
, pp. 1635-1643
-
-
Fu, L.1
Zhang, C.2
Zhang, L.Y.3
Dong, S.S.4
Lu, L.H.5
Chen, J.6
Dai, Y.7
Li, Y.8
Kong, K.L.9
Kwong, D.L.10
Guan, X.Y.11
-
35
-
-
77950844741
-
Forkhead box F1 regulates tumorpromoting properties of cancer-associated fibroblasts in lung cancer
-
PMID: 20233876
-
Saito RA, Micke P, Paulsson J, Augsten M, Peña C, Jönsson P, Botling J, Edlund K, Johansson L, Carlsson P, Jirström K, Miyazono K, Ostman A. Forkhead box F1 regulates tumorpromoting properties of cancer-associated fibroblasts in lung cancer. Cancer Res 2010; 70: 2644-2654 [PMID: 20233876 DOI: 10.1158/0008-5472.CAN-09-3644]
-
(2010)
Cancer Res
, vol.70
, pp. 2644-2654
-
-
Saito, R.A.1
Micke, P.2
Paulsson, J.3
Augsten, M.4
Peña, C.5
Jönsson, P.6
Botling, J.7
Edlund, K.8
Johansson, L.9
Carlsson, P.10
Jirström, K.11
Miyazono, K.12
Ostman, A.13
-
36
-
-
10644289454
-
Hepatocyte growth factor, its receptor, and their potential value in cancer therapies
-
PMID: 15607934
-
Jiang WG, Martin TA, Parr C, Davies G, Matsumoto K, Nakamura T. Hepatocyte growth factor, its receptor, and their potential value in cancer therapies. Crit Rev Oncol Hematol 2005; 53: 35-69 [PMID: 15607934 DOI: 10.1016/j.critrevonc.2 004.09.004]
-
(2005)
Crit Rev Oncol Hematol
, vol.53
, pp. 35-69
-
-
Jiang, W.G.1
Martin, T.A.2
Parr, C.3
Davies, G.4
Matsumoto, K.5
Nakamura, T.6
-
37
-
-
31544445490
-
Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: A metabolic survival role for tumor-associated stroma
-
PMID: 16423989
-
Koukourakis MI, Giatromanolaki A, Harris AL, Sivridis E. Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma. Cancer Res 2006; 66: 632-637 [PMID: 16423989 DOI: 10.1158/0008-5472.CAN-05-3260]
-
(2006)
Cancer Res
, vol.66
, pp. 632-637
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Harris, A.L.3
Sivridis, E.4
-
38
-
-
84877114747
-
Cancerassociated fibroblasts from hepatocellular carcinoma promote malignant cell proliferation by HGF secretion
-
PMID: 23667593
-
Jia CC, Wang TT, Liu W, Fu BS, Hua X, Wang GY, Li TJ, Li X, Wu XY, Tai Y, Zhou J, Chen GH, Zhang Q. Cancerassociated fibroblasts from hepatocellular carcinoma promote malignant cell proliferation by HGF secretion. PLoS One 2013; 8: e63243 [PMID: 23667593 DOI: 10.1371/journal. pone.0063243]
-
(2013)
PLoS One
, vol.8
, pp. e63243
-
-
Jia, C.C.1
Wang, T.T.2
Liu, W.3
Fu, B.S.4
Hua, X.5
Wang, G.Y.6
Li, T.J.7
Li, X.8
Wu, X.Y.9
Tai, Y.10
Zhou, J.11
Chen, G.H.12
Zhang, Q.13
-
39
-
-
67449110979
-
Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1
-
PMID: 19451266
-
Kuang DM, Zhao Q, Peng C, Xu J, Zhang JP, Wu C, Zheng L. Activated monocytes in peritumoral stroma of hepatocellular carcinoma foster immune privilege and disease progression through PD-L1. J Exp Med 2009; 206: 1327-1337 [PMID: 19451266 DOI: 10.1084/jem.20082173]
-
(2009)
J Exp Med
, vol.206
, pp. 1327-1337
-
-
Kuang, D.M.1
Zhao, Q.2
Peng, C.3
Xu, J.4
Zhang, J.P.5
Wu, C.6
Zheng, L.7
-
40
-
-
33747859659
-
Stromal fibroblasts in cancer: A novel tumor-promoting cell type
-
PMID: 16880743
-
Orimo A, Weinberg RA. Stromal fibroblasts in cancer: a novel tumor-promoting cell type. Cell Cycle 2006; 5: 1597-1601 [PMID: 16880743]
-
(2006)
Cell Cycle
, vol.5
, pp. 1597-1601
-
-
Orimo, A.1
Weinberg, R.A.2
-
41
-
-
33847057016
-
The androgen receptor negatively regulates the expression of c-Met: Implications for a novel mechanism of prostate cancer progression
-
PMID: 17283128
-
Verras M, Lee J, Xue H, Li TH, Wang Y, Sun Z. The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression. Cancer Res 2007; 67: 967-975 [PMID: 17283128 DOI: 10.1158/0008-5472.CAN-06-3552]
-
(2007)
Cancer Res
, vol.67
, pp. 967-975
-
-
Verras, M.1
Lee, J.2
Xue, H.3
Li, T.H.4
Wang, Y.5
Sun, Z.6
-
42
-
-
31544452076
-
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines
-
PMID: 16424029
-
Witta SE, Gemmill RM, Hirsch FR, Coldren CD, Hedman K, Ravdel L, Helfrich B, Dziadziuszko R, Chan DC, Sugita M, Chan Z, Baron A, Franklin W, Drabkin HA, Girard L, Gazdar AF, Minna JD, Bunn PA. Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines. Cancer Res 2006; 66: 944-950 [PMID: 16424029 DOI: 10.1158/0008-5472.CAN-05-1988]
-
(2006)
Cancer Res
, vol.66
, pp. 944-950
-
-
Witta, S.E.1
Gemmill, R.M.2
Hirsch, F.R.3
Coldren, C.D.4
Hedman, K.5
Ravdel, L.6
Helfrich, B.7
Dziadziuszko, R.8
Chan, D.C.9
Sugita, M.10
Chan, Z.11
Baron, A.12
Franklin, W.13
Drabkin, H.A.14
Girard, L.15
Gazdar, A.F.16
Minna, J.D.17
Bunn, P.A.18
-
43
-
-
33744465220
-
Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptors
-
PMID: 16628189
-
Jego G, Bataille R, Geffroy-Luseau A, Descamps G, Pellat-Deceunynck C. Pathogen-associated molecular patterns are growth and survival factors for human myeloma cells through Toll-like receptors. Leukemia 2006; 20: 1130-1137 [PMID: 16628189 DOI: 10.1038/sj.leu.2404226]
-
(2006)
Leukemia
, vol.20
, pp. 1130-1137
-
-
Jego, G.1
Bataille, R.2
Geffroy-Luseau, A.3
Descamps, G.4
Pellat-Deceunynck, C.5
-
44
-
-
84859394518
-
Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2
-
PMID: 22308510
-
Alcolea S, Antón R, Camacho M, Soler M, Alfranca A, Avilés-Jurado FX, Redondo JM, Quer M, León X, Vila L. Interaction between head and neck squamous cell carcinoma cells and fibroblasts in the biosynthesis of PGE2. J Lipid Res 2012; 53: 630-642 [PMID: 22308510 DOI: 10.1194/jlr.M019695]
-
(2012)
J Lipid Res
, vol.53
, pp. 630-642
-
-
Alcolea, S.1
Antón, R.2
Camacho, M.3
Soler, M.4
Alfranca, A.5
Avilés-Jurado, F.X.6
Redondo, J.M.7
Quer, M.8
León, X.9
Vila, L.10
-
45
-
-
0028197196
-
In vivo and in vitro invasiveness of a rat colon-cancer cell line maintaining E-cadherin expression: An enhancing role of tumor-associated myofibroblasts
-
PMID: 8112888
-
Dimanche-Boitrel MT, Vakaet L, Pujuguet P, Chauffert B, Martin MS, Hammann A, Van Roy F, Mareel M, Martin F. In vivo and in vitro invasiveness of a rat colon-cancer cell line maintaining E-cadherin expression: an enhancing role of tumor-associated myofibroblasts. Int J Cancer 1994; 56: 512-521 [PMID: 8112888]
-
(1994)
Int J Cancer
, vol.56
, pp. 512-521
-
-
Dimanche-Boitrel, M.T.1
Vakaet, L.2
Pujuguet, P.3
Chauffert, B.4
Martin, M.S.5
Hammann, A.6
Van Roy, F.7
Mareel, M.8
Martin, F.9
-
46
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
PMID: 15882617
-
Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005; 121: 335-348 [PMID: 15882617 DOI: 10.1016/j.cell.2005.02.034]
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
47
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing integrin signaling
-
PMID: 19931152
-
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 2009; 139: 891-906 [PMID: 19931152 DOI: 10.1016/j.cell.2009.10.027]
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
Yu, H.2
Kass, L.3
Lakins, J.N.4
Egeblad, M.5
Erler, J.T.6
Fong, S.F.7
Csiszar, K.8
Giaccia, A.9
Weninger, W.10
Yamauchi, M.11
Gasser, D.L.12
Weaver, V.M.13
-
48
-
-
20444386530
-
Coevolution of cancer and stromal cellular responses
-
PMID: 15950897
-
Littlepage LE, Egeblad M, Werb Z. Coevolution of cancer and stromal cellular responses. Cancer Cell 2005; 7: 499-500 [PMID: 15950897 DOI: 10.1016/j.ccr.2005.05.019]
-
(2005)
Cancer Cell
, vol.7
, pp. 499-500
-
-
Littlepage, L.E.1
Egeblad, M.2
Werb, Z.3
-
49
-
-
38849202330
-
Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting
-
PMID: 18232728
-
Pietras K, Pahler J, Bergers G, Hanahan D. Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting. PLoS Med 2008; 5: e19 [PMID: 18232728 DOI: 10.1371/journal.pmed.0050019]
-
(2008)
PLoS Med
, vol.5
, pp. e19
-
-
Pietras, K.1
Pahler, J.2
Bergers, G.3
Hanahan, D.4
-
50
-
-
0030823443
-
Tumor-dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis
-
PMID: 9303493
-
Olaso E, Santisteban A, Bidaurrazaga J, Gressner AM, Rosenbaum J, Vidal-Vanaclocha F. Tumor-dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis. Hepatology 1997; 26: 634-642 [PMID: 9303493 DOI: 10.1002/hep.510260315]
-
(1997)
Hepatology
, vol.26
, pp. 634-642
-
-
Olaso, E.1
Santisteban, A.2
Bidaurrazaga, J.3
Gressner, A.M.4
Rosenbaum, J.5
Vidal-Vanaclocha, F.6
-
51
-
-
77954635026
-
Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion
-
PMID: 20534479
-
Grugan KD, Miller CG, Yao Y, Michaylira CZ, Ohashi S, Klein-Szanto AJ, Diehl JA, Herlyn M, Han M, Nakagawa H, Rustgi AK. Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion. Proc Natl Acad Sci USA 2010; 107: 11026-11031 [PMID: 20534479 DOI: 10.1073/pnas.0914295107]
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 11026-11031
-
-
Grugan, K.D.1
Miller, C.G.2
Yao, Y.3
Michaylira, C.Z.4
Ohashi, S.5
Klein-Szanto, A.J.6
Diehl, J.A.7
Herlyn, M.8
Han, M.9
Nakagawa, H.10
Rustgi, A.K.11
-
52
-
-
70349252148
-
The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo
-
PMID: 19569239
-
Li L, Dragulev B, Zigrino P, Mauch C, Fox JW. The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo. Int J Cancer 2009; 125: 1796-1804 [PMID: 19569239 DOI: 10.1002/ijc.24463]
-
(2009)
Int J Cancer
, vol.125
, pp. 1796-1804
-
-
Li, L.1
Dragulev, B.2
Zigrino, P.3
Mauch, C.4
Fox, J.W.5
-
53
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
PMID: 20371345
-
Kessenbrock K, Plaks V, Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 2010; 141: 52-67 [PMID: 20371345 DOI: 10.1016/j.cell.2010.03.015]
-
(2010)
Cell
, vol.141
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
-
54
-
-
13544255506
-
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells
-
PMID: 15707890
-
Boire A, Covic L, Agarwal A, Jacques S, Sherifi S, Kuliopulos A. PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell 2005; 120: 303-313 [PMID: 15707890 DOI: 10.1016/j.cell.2004.12.018]
-
(2005)
Cell
, vol.120
, pp. 303-313
-
-
Boire, A.1
Covic, L.2
Agarwal, A.3
Jacques, S.4
Sherifi, S.5
Kuliopulos, A.6
-
55
-
-
21344435775
-
Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer
-
PMID: 16264989
-
Haura EB, Turkson J, Jove R. Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer. Nat Clin Pract Oncol 2005; 2: 315-324 [PMID: 16264989 DOI: 10.1038/ncponc0195]
-
(2005)
Nat Clin Pract Oncol
, vol.2
, pp. 315-324
-
-
Haura, E.B.1
Turkson, J.2
Jove, R.3
-
56
-
-
0029846756
-
Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice
-
PMID: 8910279
-
Cressman DE, Greenbaum LE, DeAngelis RA, Ciliberto G, Furth EE, Poli V, Taub R. Liver failure and defective hepatocyte regeneration in interleukin-6-deficient mice. Science 1996; 274: 1379-1383 [PMID: 8910279]
-
(1996)
Science
, vol.274
, pp. 1379-1383
-
-
Cressman, D.E.1
Greenbaum, L.E.2
DeAngelis, R.A.3
Ciliberto, G.4
Furth, E.E.5
Poli, V.6
Taub, R.7
-
57
-
-
84883377982
-
Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma
-
PMID: 23993096
-
Zhang XH, Jin X, Malladi S, Zou Y, Wen YH, Brogi E, Smid M, Foekens JA, Massagué J. Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma. Cell 2013; 154: 1060-1073 [PMID: 23993096 DOI: 10.1016/ j.cell.2013.07.036]
-
(2013)
Cell
, vol.154
, pp. 1060-1073
-
-
Zhang, X.H.1
Jin, X.2
Malladi, S.3
Zou, Y.4
Wen, Y.H.5
Brogi, E.6
Smid, M.7
Foekens, J.A.8
Massagué, J.9
-
58
-
-
78650739435
-
Malignant cells facilitate lung metastasis by bringing their own soil
-
PMID: 21098274
-
Duda DG, Duyverman AM, Kohno M, Snuderl M, Steller EJ, Fukumura D, Jain RK. Malignant cells facilitate lung metastasis by bringing their own soil. Proc Natl Acad Sci USA 2010; 107: 21677-21682 [PMID: 21098274 DOI: 10.1073/pnas.1016234107]
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21677-21682
-
-
Duda, D.G.1
Duyverman, A.M.2
Kohno, M.3
Snuderl, M.4
Steller, E.J.5
Fukumura, D.6
Jain, R.K.7
-
59
-
-
78049517433
-
Mesenchymal stem cells enhance growth and metastasis of colon cancer
-
PMID: 20473928
-
Shinagawa K, Kitadai Y, Tanaka M, Sumida T, Kodama M, Higashi Y, Tanaka S, Yasui W, Chayama K. Mesenchymal stem cells enhance growth and metastasis of colon cancer. Int J Cancer 2010; 127: 2323-2333 [PMID: 20473928 DOI: 10.1002/ijc.25440]
-
(2010)
Int J Cancer
, vol.127
, pp. 2323-2333
-
-
Shinagawa, K.1
Kitadai, Y.2
Tanaka, M.3
Sumida, T.4
Kodama, M.5
Higashi, Y.6
Tanaka, S.7
Yasui, W.8
Chayama, K.9
-
60
-
-
84897538576
-
Carcinoma-associated fibroblasts provide operational flexibility in metastasis
-
PMID: 24406210
-
De Wever O, Van Bockstal M, Mareel M, Hendrix A, Bracke M. Carcinoma-associated fibroblasts provide operational flexibility in metastasis. Semin Cancer Biol 2014; 25: 33-46 [PMID: 24406210 DOI: 10.1016/j.semcancer.2013.12.009]
-
(2014)
Semin Cancer Biol
, vol.25
, pp. 33-46
-
-
De Wever, O.1
Van Bockstal, M.2
Mareel, M.3
Hendrix, A.4
Bracke, M.5
-
61
-
-
46049104966
-
Outcomes after radiotherapy for basaloid squamous cell carcinoma of the head and neck: A casecontrol study
-
PMID: 18429002
-
Thariat J, Ahamad A, El-Naggar AK, Williams MD, Holsinger FC, Glisson BS, Allen PK, Morrison WH, Weber RS, Ang KK, Garden AS. Outcomes after radiotherapy for basaloid squamous cell carcinoma of the head and neck: a casecontrol study. Cancer 2008; 112: 2698-2709 [PMID: 18429002 DOI: 10.1002/cncr.23486]
-
(2008)
Cancer
, vol.112
, pp. 2698-2709
-
-
Thariat, J.1
Ahamad, A.2
El-Naggar, A.K.3
Williams, M.D.4
Holsinger, F.C.5
Glisson, B.S.6
Allen, P.K.7
Morrison, W.H.8
Weber, R.S.9
Ang, K.K.10
Garden, A.S.11
-
62
-
-
28644432204
-
VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche
-
PMID: 16341007
-
Kaplan RN, Riba RD, Zacharoulis S, Bramley AH, Vincent L, Costa C, MacDonald DD, Jin DK, Shido K, Kerns SA, Zhu Z, Hicklin D, Wu Y, Port JL, Altorki N, Port ER, Ruggero D, Shmelkov SV, Jensen KK, Rafii S, Lyden D. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche. Nature 2005; 438: 820-827 [PMID: 16341007 DOI: 10.1038/nature04186]
-
(2005)
Nature
, vol.438
, pp. 820-827
-
-
Kaplan, R.N.1
Riba, R.D.2
Zacharoulis, S.3
Bramley, A.H.4
Vincent, L.5
Costa, C.6
MacDonald, D.D.7
Jin, D.K.8
Shido, K.9
Kerns, S.A.10
Zhu, Z.11
Hicklin, D.12
Wu, Y.13
Port, J.L.14
Altorki, N.15
Port, E.R.16
Ruggero, D.17
Shmelkov, S.V.18
Jensen, K.K.19
Rafii, S.20
Lyden, D.21
more..
-
63
-
-
57849100048
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
PMID: 19111879
-
Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, Le QT, Giaccia AJ. Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Cancer Cell 2009; 15: 35-44 [PMID: 19111879 DOI: 10.1016/j.ccr.2008.11.012]
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
Bennewith, K.L.2
Cox, T.R.3
Lang, G.4
Bird, D.5
Koong, A.6
Le, Q.T.7
Giaccia, A.J.8
-
64
-
-
84873303427
-
Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis
-
PMID: 23081697
-
Zhao L, Lim SY, Gordon-Weeks AN, Tapmeier TT, Im JH, Cao Y, Beech J, Allen D, Smart S, Muschel RJ. Recruitment of a myeloid cell subset (CD11b/Gr1 mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis. Hepatology 2013; 57: 829-839 [PMID: 23081697 DOI: 10.1002/hep.26094]
-
(2013)
Hepatology
, vol.57
, pp. 829-839
-
-
Zhao, L.1
Lim, S.Y.2
Gordon-Weeks, A.N.3
Tapmeier, T.T.4
Im, J.H.5
Cao, Y.6
Beech, J.7
Allen, D.8
Smart, S.9
Muschel, R.J.10
-
65
-
-
84869021181
-
Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation
-
PMID: 23153532
-
Calon A, Espinet E, Palomo-Ponce S, Tauriello DV, Iglesias M, Céspedes MV, Sevillano M, Nadal C, Jung P, Zhang XH, Byrom D, Riera A, Rossell D, Mangues R, Massagué J, Sancho E, Batlle E. Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation. Cancer Cell 2012; 22: 571-584 [PMID: 23153532 DOI: 10.1016/j.ccr.2012.08.013]
-
(2012)
Cancer Cell
, vol.22
, pp. 571-584
-
-
Calon, A.1
Espinet, E.2
Palomo-Ponce, S.3
Tauriello, D.V.4
Iglesias, M.5
Céspedes, M.V.6
Sevillano, M.7
Nadal, C.8
Jung, P.9
Zhang, X.H.10
Byrom, D.11
Riera, A.12
Rossell, D.13
Mangues, R.14
Massagué, J.15
Sancho, E.16
Batlle, E.17
-
66
-
-
80053996706
-
GSTPi-positive tumour microenvironment-associated fibroblasts are significantly associated with GSTPi-negative cancer cells in paired cases of primary invasive breast cancer and axillary lymph node metastases
-
PMID: 21897388
-
Chaiwun B, Sukhamwang N, Trakultivakorn H, Saha B, Young L, Tsao-Wei D, Naritoku WY, Groshen S, Taylor CR, Imam SA. GSTPi-positive tumour microenvironment-associated fibroblasts are significantly associated with GSTPi-negative cancer cells in paired cases of primary invasive breast cancer and axillary lymph node metastases. Br J Cancer 2011; 105: 1224-1229 [PMID: 21897388 DOI: 10.1038/bjc.2011.352]
-
(2011)
Br J Cancer
, vol.105
, pp. 1224-1229
-
-
Chaiwun, B.1
Sukhamwang, N.2
Trakultivakorn, H.3
Saha, B.4
Young, L.5
Tsao-Wei, D.6
Naritoku, W.Y.7
Groshen, S.8
Taylor, C.R.9
Imam, S.A.10
-
67
-
-
79956116498
-
Role for stromal heterogeneity in prostate tumorigenesis
-
PMID: 21444670
-
Kiskowski MA, Jackson RS, Banerjee J, Li X, Kang M, Iturregui JM, Franco OE, Hayward SW, Bhowmick NA. Role for stromal heterogeneity in prostate tumorigenesis. Cancer Res 2011; 71: 3459-3470 [PMID: 21444670 DOI: 10.1158/0008-5472.CAN-10-2999]
-
(2011)
Cancer Res
, vol.71
, pp. 3459-3470
-
-
Kiskowski, M.A.1
Jackson, R.S.2
Banerjee, J.3
Li, X.4
Kang, M.5
Iturregui, J.M.6
Franco, O.E.7
Hayward, S.W.8
Bhowmick, N.A.9
-
68
-
-
84880072376
-
Identification of two distinct carci-noma-associated fibroblast subtypes with differential tumorpromoting abilities in oral squamous cell carcinoma
-
PMID: 23598279
-
Costea DE, Hills A, Osman AH, Thurlow J, Kalna G, Huang X, Pena Murillo C, Parajuli H, Suliman S, Kulasekara KK, Johannessen AC, Partridge M. Identification of two distinct carci-noma-associated fibroblast subtypes with differential tumorpromoting abilities in oral squamous cell carcinoma. Cancer Res 2013; 73: 3888-3901 [PMID: 23598279 DOI: 10.1158/0008-5472.CAN-12-4150]
-
(2013)
Cancer Res
, vol.73
, pp. 3888-3901
-
-
Costea, D.E.1
Hills, A.2
Osman, A.H.3
Thurlow, J.4
Kalna, G.5
Huang, X.6
Pena Murillo, C.7
Parajuli, H.8
Suliman, S.9
Kulasekara, K.K.10
Johannessen, A.C.11
Partridge, M.12
-
69
-
-
84870547819
-
Cell-extrinsic consequences of epithelial stress: Activation of protumorigenic tissue phenotypes
-
PMID: 23216814
-
Fordyce CA, Patten KT, Fessenden TB, DeFilippis R, Hwang ES, Zhao J, Tlsty TD. Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes. Breast Cancer Res 2012; 14: R155 [PMID: 23216814 DOI: 10.1186/ bcr3368]
-
(2012)
Breast Cancer Res
, vol.14
, pp. R155
-
-
Fordyce, C.A.1
Patten, K.T.2
Fessenden, T.B.3
DeFilippis, R.4
Hwang, E.S.5
Zhao, J.6
Tlsty, T.D.7
-
70
-
-
33646350741
-
The role of matrix metal-loproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pylori
-
PMID: 16697739
-
McCaig C, Duval C, Hemers E, Steele I, Pritchard DM, Przemeck S, Dimaline R, Ahmed S, Bodger K, Kerrigan DD, Wang TC, Dockray GJ, Varro A. The role of matrix metal-loproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pylori. Gastroenterology 2006; 130: 1754-1763 [PMID: 16697739 DOI: 10.1053/j.gastro.2006.02.031]
-
(2006)
Gastroenterology
, vol.130
, pp. 1754-1763
-
-
McCaig, C.1
Duval, C.2
Hemers, E.3
Steele, I.4
Pritchard, D.M.5
Przemeck, S.6
Dimaline, R.7
Ahmed, S.8
Bodger, K.9
Kerrigan, D.D.10
Wang, T.C.11
Dockray, G.J.12
Varro, A.13
-
71
-
-
34047127376
-
PDGF receptors as targets in tumor treatment
-
PMID: 17419949
-
Ostman A, Heldin CH. PDGF receptors as targets in tumor treatment. Adv Cancer Res 2007; 97: 247-274 [PMID: 17419949 DOI: 10.1016/S0065-230X(06)97011-0]
-
(2007)
Adv Cancer Res
, vol.97
, pp. 247-274
-
-
Ostman, A.1
Heldin, C.H.2
-
72
-
-
84879483263
-
Progastrin-induced secretion of insulin-like growth factor 2 from colonic myofibroblasts stimulates colonic epithelial proliferation in mice
-
e3 PMID: 23523669
-
Duckworth CA, Clyde D, Worthley DL, Wang TC, Varro A, Pritchard DM. Progastrin-induced secretion of insulin-like growth factor 2 from colonic myofibroblasts stimulates colonic epithelial proliferation in mice. Gastroenterology 2013; 145: 197-208, e3 [PMID: 23523669 DOI: 10.1053/j.gastro.2013.03.012]
-
(2013)
Gastroenterology
, vol.145
, pp. 197-208
-
-
Duckworth, C.A.1
Clyde, D.2
Worthley, D.L.3
Wang, T.C.4
Varro, A.5
Pritchard, D.M.6
-
73
-
-
77949719411
-
Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancerassociated fibroblasts
-
PMID: 20215540
-
Walter K, Omura N, Hong SM, Griffith M, Vincent A, Borges M, Goggins M. Overexpression of smoothened activates the sonic hedgehog signaling pathway in pancreatic cancerassociated fibroblasts. Clin Cancer Res 2010; 16: 1781-1789 [PMID: 20215540 DOI: 10.1158/1078-0432.CCR-09-1913]
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1781-1789
-
-
Walter, K.1
Omura, N.2
Hong, S.M.3
Griffith, M.4
Vincent, A.5
Borges, M.6
Goggins, M.7
-
74
-
-
84878615570
-
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
-
PMID: 23708000
-
Calvo F, Ege N, Grande-Garcia A, Hooper S, Jenkins RP, Chaudhry SI, Harrington K, Williamson P, Moeendarbary E, Charras G, Sahai E. Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nat Cell Biol 2013; 15: 637-646 [PMID: 23708000 DOI: 10.1038/ncb2756]
-
(2013)
Nat Cell Biol
, vol.15
, pp. 637-646
-
-
Calvo, F.1
Ege, N.2
Grande-Garcia, A.3
Hooper, S.4
Jenkins, R.P.5
Chaudhry, S.I.6
Harrington, K.7
Williamson, P.8
Moeendarbary, E.9
Charras, G.10
Sahai, E.11
-
75
-
-
79953727008
-
Osteopontin promotes CCL5-mesenchymal stromal cellmediated breast cancer metastasis
-
PMID: 21252118
-
Mi Z, Bhattacharya SD, Kim VM, Guo H, Talbot LJ, Kuo PC. Osteopontin promotes CCL5-mesenchymal stromal cellmediated breast cancer metastasis. Carcinogenesis 2011; 32: 477-487 [PMID: 21252118 DOI: 10.1093/carcin/bgr009]
-
(2011)
Carcinogenesis
, vol.32
, pp. 477-487
-
-
Mi, Z.1
Bhattacharya, S.D.2
Kim, V.M.3
Guo, H.4
Talbot, L.J.5
Kuo, P.C.6
-
76
-
-
84866095889
-
Discoidin domain receptor 2 deficiency predisposes hepatic tissue to colon carcinoma metastasis
-
PMID: 22071959
-
Badiola I, Olaso E, Crende O, Friedman SL, Vidal-Vanaclocha F. Discoidin domain receptor 2 deficiency predisposes hepatic tissue to colon carcinoma metastasis. Gut 2012; 61: 1465-1472 [PMID: 22071959 DOI: 10.1136/gutjnl-2011-300810]
-
(2012)
Gut
, vol.61
, pp. 1465-1472
-
-
Badiola, I.1
Olaso, E.2
Crende, O.3
Friedman, S.L.4
Vidal-Vanaclocha, F.5
-
77
-
-
84874598384
-
IQGAP1 suppresses TßRII-mediated myofibroblastic activation and metastatic growth in liver
-
PMID: 23454766
-
Liu C, Billadeau DD, Abdelhakim H, Leof E, Kaibuchi K, Bernabeu C, Bloom GS, Yang L, Boardman L, Shah VH, Kang N. IQGAP1 suppresses TßRII-mediated myofibroblastic activation and metastatic growth in liver. J Clin Invest 2013; 123: 1138-1156 [PMID: 23454766 DOI: 10.1172/JCI63836]
-
(2013)
J Clin Invest
, vol.123
, pp. 1138-1156
-
-
Liu, C.1
Billadeau, D.D.2
Abdelhakim, H.3
Leof, E.4
Kaibuchi, K.5
Bernabeu, C.6
Bloom, G.S.7
Yang, L.8
Boardman, L.9
Shah, V.H.10
Kang, N.11
-
78
-
-
84874637012
-
Exosomal tumor microRNA modulates premetastatic organ cells
-
PMID: 23479506
-
Rana S, Malinowska K, Zöller M. Exosomal tumor microRNA modulates premetastatic organ cells. Neoplasia 2013; 15: 281-295 [PMID: 23479506]
-
(2013)
Neoplasia
, vol.15
, pp. 281-295
-
-
Rana, S.1
Malinowska, K.2
Zöller, M.3
-
79
-
-
84871528926
-
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer
-
PMID: 23171795
-
Mitra AK, Zillhardt M, Hua Y, Tiwari P, Murmann AE, Peter ME, Lengyel E. MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer. Cancer Discov 2012; 2: 1100-1108 [PMID: 23171795 DOI: 10.1158/2159-8290.CD-12-0206]
-
(2012)
Cancer Discov
, vol.2
, pp. 1100-1108
-
-
Mitra, A.K.1
Zillhardt, M.2
Hua, Y.3
Tiwari, P.4
Murmann, A.E.5
Peter, M.E.6
Lengyel, E.7
-
80
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
-
PMID: 22635005
-
Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med 2012; 18: 883-891 [PMID: 22635005 DOI: 10.1038/nm.2753]
-
(2012)
Nat Med
, vol.18
, pp. 883-891
-
-
Peinado, H.1
Alečković, M.2
Lavotshkin, S.3
Matei, I.4
Costa-Silva, B.5
Moreno-Bueno, G.6
Hergueta-Redondo, M.7
Williams, C.8
García-Santos, G.9
Ghajar, C.10
Nitadori-Hoshino, A.11
Hoffman, C.12
Badal, K.13
Garcia, B.A.14
Callahan, M.K.15
Yuan, J.16
Martins, V.R.17
Skog, J.18
Kaplan, R.N.19
Brady, M.S.20
Wolchok, J.D.21
Chapman, P.B.22
Kang, Y.23
Bromberg, J.24
Lyden, D.25
more..
-
81
-
-
78649958307
-
Cancer exosomes trigger fibroblast to myofibroblast differentiation
-
PMID: 21098712
-
Webber J, Steadman R, Mason MD, Tabi Z, Clayton A. Cancer exosomes trigger fibroblast to myofibroblast differentiation. Cancer Res 2010; 70: 9621-9630 [PMID: 21098712 DOI: 10.1158/0008-5472.CAN-10-1722]
-
(2010)
Cancer Res
, vol.70
, pp. 9621-9630
-
-
Webber, J.1
Steadman, R.2
Mason, M.D.3
Tabi, Z.4
Clayton, A.5
-
82
-
-
84902469661
-
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
-
PMID: 24856586
-
Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell 2014; 25: 719-734 [PMID: 24856586 DOI: 10.1016/j.ccr.2014.04.005]
-
(2014)
Cancer Cell
, vol.25
, pp. 719-734
-
-
Özdemir, B.C.1
Pentcheva-Hoang, T.2
Carstens, J.L.3
Zheng, X.4
Wu, C.C.5
Simpson, T.R.6
Laklai, H.7
Sugimoto, H.8
Kahlert, C.9
Novitskiy, S.V.10
De Jesus-Acosta, A.11
Sharma, P.12
Heidari, P.13
Mahmood, U.14
Chin, L.15
Moses, H.L.16
Weaver, V.M.17
Maitra, A.18
Allison, J.P.19
LeBleu, V.S.20
Kalluri, R.21
more..
-
83
-
-
84885079983
-
FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer
-
PMID: 23943801
-
Liu R, Li J, Xie K, Zhang T, Lei Y, Chen Y, Zhang L, Huang K, Wang K, Wu H, Wu M, Nice EC, Huang C, Wei Y. FGFR4 promotes stroma-induced epithelial-to-mesenchymal transition in colorectal cancer. Cancer Res 2013; 73: 5926-5935 [PMID: 23943801 DOI: 10.1158/0008-5472.CAN-12-4718]
-
(2013)
Cancer Res
, vol.73
, pp. 5926-5935
-
-
Liu, R.1
Li, J.2
Xie, K.3
Zhang, T.4
Lei, Y.5
Chen, Y.6
Zhang, L.7
Huang, K.8
Wang, K.9
Wu, H.10
Wu, M.11
Nice, E.C.12
Huang, C.13
Wei, Y.14
-
84
-
-
84871563123
-
Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration
-
PMID: 23260141
-
Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL. Exosomes mediate stromal mobilization of autocrine Wnt-PCP signaling in breast cancer cell migration. Cell 2012; 151: 1542-1556 [PMID: 23260141 DOI: 10.1016/j.cell.2012.11.024]
-
(2012)
Cell
, vol.151
, pp. 1542-1556
-
-
Luga, V.1
Zhang, L.2
Viloria-Petit, A.M.3
Ogunjimi, A.A.4
Inanlou, M.R.5
Chiu, E.6
Buchanan, M.7
Hosein, A.N.8
Basik, M.9
Wrana, J.L.10
-
85
-
-
84881535703
-
Stromal EGF and igf-I together modulate plasticity of disseminated triple-negative breast tumors
-
PMID: 23689072
-
Castaño Z, Marsh T, Tadipatri R, Kuznetsov HS, Al-Shahrour F, Paktinat M, Greene-Colozzi A, Nilsson B, Richardson AL, McAllister SS. Stromal EGF and igf-I together modulate plasticity of disseminated triple-negative breast tumors. Cancer Discov 2013; 3: 922-935 [PMID: 23689072 DOI: 10.1158/2159-8290.CD-13-0041]
-
(2013)
Cancer Discov
, vol.3
, pp. 922-935
-
-
Castaño, Z.1
Marsh, T.2
Tadipatri, R.3
Kuznetsov, H.S.4
Al-Shahrour, F.5
Paktinat, M.6
Greene-Colozzi, A.7
Nilsson, B.8
Richardson, A.L.9
McAllister, S.S.10
-
86
-
-
84879071318
-
Hepatocellular carcinoma-associated mesenchymal stem cells promote hepatocarcinoma progression: Role of the S100A4-miR155-SOCS1-MMP9 axis
-
PMID: 23316018
-
Yan XL, Jia YL, Chen L, Zeng Q, Zhou JN, Fu CJ, Chen HX, Yuan HF, Li ZW, Shi L, Xu YC, Wang JX, Zhang XM, He LJ, Zhai C, Yue W, Pei XT. Hepatocellular carcinoma-associated mesenchymal stem cells promote hepatocarcinoma progression: role of the S100A4-miR155-SOCS1-MMP9 axis. Hepatology 2013; 57: 2274-2286 [PMID: 23316018 DOI: 10.1002/hep.26257]
-
(2013)
Hepatology
, vol.57
, pp. 2274-2286
-
-
Yan, X.L.1
Jia, Y.L.2
Chen, L.3
Zeng, Q.4
Zhou, J.N.5
Fu, C.J.6
Chen, H.X.7
Yuan, H.F.8
Li, Z.W.9
Shi, L.10
Xu, Y.C.11
Wang, J.X.12
Zhang, X.M.13
He, L.J.14
Zhai, C.15
Yue, W.16
Pei, X.T.17
-
87
-
-
84874336387
-
STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer
-
PMID: 23243022
-
Peña C, Céspedes MV, Lindh MB, Kiflemariam S, Mezheyeuski A, Edqvist PH, Hägglöf C, Birgisson H, Bojmar L, Jirström K, Sandström P, Olsson E, Veerla S, Gallardo A, Sjöblom T, Chang AC, Reddel RR, Mangues R, Augsten M, Ostman A. STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer. Cancer Res 2013; 73: 1287-1297 [PMID: 23243022 DOI: 10.1158/0008-5472.CAN-12-1875]
-
(2013)
Cancer Res
, vol.73
, pp. 1287-1297
-
-
Peña, C.1
Céspedes, M.V.2
Lindh, M.B.3
Kiflemariam, S.4
Mezheyeuski, A.5
Edqvist, P.H.6
Hägglöf, C.7
Birgisson, H.8
Bojmar, L.9
Jirström, K.10
Sandström, P.11
Olsson, E.12
Veerla, S.13
Gallardo, A.14
Sjöblom, T.15
Chang, A.C.16
Reddel, R.R.17
Mangues, R.18
Augsten, M.19
Ostman, A.20
more..
-
88
-
-
77957732541
-
LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells
-
PMID: 20876278
-
Scott RW, Hooper S, Crighton D, Li A, König I, Munro J, Trivier E, Wickman G, Morin P, Croft DR, Dawson J, Machesky L, Anderson KI, Sahai EA, Olson MF. LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells. J Cell Biol 2010; 191: 169-185 [PMID: 20876278 DOI: 10.1083/jcb.201002041]
-
(2010)
J Cell Biol
, vol.191
, pp. 169-185
-
-
Scott, R.W.1
Hooper, S.2
Crighton, D.3
Li, A.4
König, I.5
Munro, J.6
Trivier, E.7
Wickman, G.8
Morin, P.9
Croft, D.R.10
Dawson, J.11
Machesky, L.12
Anderson, K.I.13
Sahai, E.A.14
Olson, M.F.15
-
89
-
-
36749013537
-
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
-
PMID: 18037882
-
Gaggioli C, Hooper S, Hidalgo-Carcedo C, Grosse R, Marshall JF, Harrington K, Sahai E. Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells. Nat Cell Biol 2007; 9: 1392-1400 [PMID: 18037882 DOI: 10.1038/ncb1658]
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1392-1400
-
-
Gaggioli, C.1
Hooper, S.2
Hidalgo-Carcedo, C.3
Grosse, R.4
Marshall, J.F.5
Harrington, K.6
Sahai, E.7
-
90
-
-
79551565642
-
Tumor cell invasion is promoted by interstitial flow-induced matrix priming by stromal fibroblasts
-
PMID: 21245098
-
Shieh AC, Rozansky HA, Hinz B, Swartz MA. Tumor cell invasion is promoted by interstitial flow-induced matrix priming by stromal fibroblasts. Cancer Res 2011; 71: 790-800 [PMID: 21245098 DOI: 10.1158/0008-5472.CAN-10-1513]
-
(2011)
Cancer Res
, vol.71
, pp. 790-800
-
-
Shieh, A.C.1
Rozansky, H.A.2
Hinz, B.3
Swartz, M.A.4
-
91
-
-
57749106585
-
Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells
-
PMID: 19074894
-
Lin HJ, Zuo T, Lin CH, Kuo CT, Liyanarachchi S, Sun S, Shen R, Deatherage DE, Potter D, Asamoto L, Lin S, Yan PS, Cheng AL, Ostrowski MC, Huang TH. Breast cancer-associated fibroblasts confer AKT1-mediated epigenetic silencing of Cystatin M in epithelial cells. Cancer Res 2008; 68: 10257-10266 [PMID: 19074894 DOI: 10.1158/0008-5472.CAN-08-0288]
-
(2008)
Cancer Res
, vol.68
, pp. 10257-10266
-
-
Lin, H.J.1
Zuo, T.2
Lin, C.H.3
Kuo, C.T.4
Liyanarachchi, S.5
Sun, S.6
Shen, R.7
Deatherage, D.E.8
Potter, D.9
Asamoto, L.10
Lin, S.11
Yan, P.S.12
Cheng, A.L.13
Ostrowski, M.C.14
Huang, T.H.15
-
92
-
-
84873804360
-
Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis
-
PMID: 23318994
-
Chaturvedi P, Gilkes DM, Wong CC, Luo W, Zhang H, Wei H, Takano N, Schito L, Levchenko A, Semenza GL. Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis. J Clin Invest 2013; 123: 189-205 [PMID: 23318994 DOI: 10.1172/JCI64993]
-
(2013)
J Clin Invest
, vol.123
, pp. 189-205
-
-
Chaturvedi, P.1
Gilkes, D.M.2
Wong, C.C.3
Luo, W.4
Zhang, H.5
Wei, H.6
Takano, N.7
Schito, L.8
Levchenko, A.9
Semenza, G.L.10
-
93
-
-
84855425160
-
Interactions between cancer stem cells and their niche govern metastatic colonization
-
PMID: 22158103
-
Malanchi I, Santamaria-Martínez A, Susanto E, Peng H, Lehr HA, Delaloye JF, Huelsken J. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature 2012; 481: 85-89 [PMID: 22158103 DOI: 10.1038/nature10694]
-
(2012)
Nature
, vol.481
, pp. 85-89
-
-
Malanchi, I.1
Santamaria-Martínez, A.2
Susanto, E.3
Peng, H.4
Lehr, H.A.5
Delaloye, J.F.6
Huelsken, J.7
-
94
-
-
77956425361
-
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment
-
PMID: 20818376
-
Barry-Hamilton V, Spangler R, Marshall D, McCauley S, Rodriguez HM, Oyasu M, Mikels A, Vaysberg M, Ghermazien H, Wai C, Garcia CA, Velayo AC, Jorgensen B, Biermann D, Tsai D, Green J, Zaffryar-Eilot S, Holzer A, Ogg S, Thai D, Neufeld G, Van Vlasselaer P, Smith V. Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat Med 2010; 16: 1009-1017 [PMID: 20818376 DOI: 10.1038/nm.2208]
-
(2010)
Nat Med
, vol.16
, pp. 1009-1017
-
-
Barry-Hamilton, V.1
Spangler, R.2
Marshall, D.3
McCauley, S.4
Rodriguez, H.M.5
Oyasu, M.6
Mikels, A.7
Vaysberg, M.8
Ghermazien, H.9
Wai, C.10
Garcia, C.A.11
Velayo, A.C.12
Jorgensen, B.13
Biermann, D.14
Tsai, D.15
Green, J.16
Zaffryar-Eilot, S.17
Holzer, A.18
Ogg, S.19
Thai, D.20
Neufeld, G.21
Van Vlasselaer, P.22
Smith, V.23
more..
-
95
-
-
84874666281
-
Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling
-
PMID: 22535374
-
De Boeck A, Pauwels P, Hensen K, Rummens JL, Westbroek W, Hendrix A, Maynard D, Denys H, Lambein K, Braems G, Gespach C, Bracke M, De Wever O. Bone marrow-derived mesenchymal stem cells promote colorectal cancer progression through paracrine neuregulin 1/HER3 signalling. Gut 2013; 62: 550-560 [PMID: 22535374 DOI: 10.1136/gutjnl-2011-301393]
-
(2013)
Gut
, vol.62
, pp. 550-560
-
-
De Boeck, A.1
Pauwels, P.2
Hensen, K.3
Rummens, J.L.4
Westbroek, W.5
Hendrix, A.6
Maynard, D.7
Denys, H.8
Lambein, K.9
Braems, G.10
Gespach, C.11
Bracke, M.12
De Wever, O.13
-
96
-
-
84877724314
-
Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis
-
PMID: 23653207
-
Jung Y, Kim JK, Shiozawa Y, Wang J, Mishra A, Joseph J, Berry JE, McGee S, Lee E, Sun H, Wang J, Jin T, Zhang H, Dai J, Krebsbach PH, Keller ET, Pienta KJ, Taichman RS. Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis. Nat Commun 2013; 4: 1795 [PMID: 23653207 DOI: 10.1038/ncomms2766]
-
(2013)
Nat Commun
, vol.4
, pp. 1795
-
-
Jung, Y.1
Kim, J.K.2
Shiozawa, Y.3
Wang, J.4
Mishra, A.5
Joseph, J.6
Berry, J.E.7
McGee, S.8
Lee, E.9
Sun, H.10
Wang, J.11
Jin, T.12
Zhang, H.13
Dai, J.14
Krebsbach, P.H.15
Keller, E.T.16
Pienta, K.J.17
Taichman, R.S.18
-
97
-
-
5444248307
-
Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent proinvasive signals to human colon cancer cells through RhoA and Rac
-
PMID: 15059978
-
De Wever O, Nguyen QD, Van Hoorde L, Bracke M, Bruyneel E, Gespach C, Mareel M. Tenascin-C and SF/HGF produced by myofibroblasts in vitro provide convergent proinvasive signals to human colon cancer cells through RhoA and Rac. FASEB J 2004; 18: 1016-1018 [PMID: 15059978 DOI: 10.1096/fj.03-1110fje]
-
(2004)
FASEB J
, vol.18
, pp. 1016-1018
-
-
De Wever, O.1
Nguyen, Q.D.2
Van Hoorde, L.3
Bracke, M.4
Bruyneel, E.5
Gespach, C.6
Mareel, M.7
-
98
-
-
77951975325
-
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
-
PMID: 20418870
-
Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP. Wnt activity defines colon cancer stem cells and is regulated by the microenvironment. Nat Cell Biol 2010; 12: 468-476 [PMID: 20418870 DOI: 10.1038/ncb2048]
-
(2010)
Nat Cell Biol
, vol.12
, pp. 468-476
-
-
Vermeulen, L.1
De Sousa, E.2
Melo, F.3
Van Der Heijden, M.4
Cameron, K.5
De Jong, J.H.6
Borovski, T.7
Tuynman, J.B.8
Todaro, M.9
Merz, C.10
Rodermond, H.11
Sprick, M.R.12
Kemper, K.13
Richel, D.J.14
Stassi, G.15
Medema, J.P.16
-
99
-
-
84887015073
-
Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model
-
PMID: 24139798
-
Saupe F, Schwenzer A, Jia Y, Gasser I, Spenlé C, Langlois B, Kammerer M, Lefebvre O, Hlushchuk R, Rupp T, Marko M, van der Heyden M, Cremel G, Arnold C, Klein A, Simon-Assmann P, Djonov V, Neuville-Méchine A, Esposito I, Slotta-Huspenina J, Janssen KP, de Wever O, Christofori G, Hussenet T, Orend G. Tenascin-C downregulates wnt inhibitor dickkopf-1, promoting tumorigenesis in a neuroendocrine tumor model. Cell Rep 2013; 5: 482-492 [PMID: 24139798 DOI: 10.1016/j.celrep.2013.09.014]
-
(2013)
Cell Rep
, vol.5
, pp. 482-492
-
-
Saupe, F.1
Schwenzer, A.2
Jia, Y.3
Gasser, I.4
Spenlé, C.5
Langlois, B.6
Kammerer, M.7
Lefebvre, O.8
Hlushchuk, R.9
Rupp, T.10
Marko, M.11
Van Der Heyden, M.12
Cremel, G.13
Arnold, C.14
Klein, A.15
Simon-Assmann, P.16
Djonov, V.17
Neuville-Méchine, A.18
Esposito, I.19
Slotta-Huspenina, J.20
Janssen, K.P.21
De Wever, O.22
Christofori, G.23
Hussenet, T.24
Orend, G.25
more..
-
100
-
-
84904602423
-
A monotonic and prognostic genomic signature from fibroblasts for colorectal cancer initiation, progression, and metastasis
-
PMID: 24829396
-
Berdiel-Acer M, Cuadras D, Díaz-Maroto NG, Sanjuan X, Serrano T, Berenguer A, Moreno V, Gonçalves-Ribeiro S, Salazar R, Villanueva A, Molleví DG. A monotonic and prognostic genomic signature from fibroblasts for colorectal cancer initiation, progression, and metastasis. Mol Cancer Res 2014; 12: 1254-1266 [PMID: 24829396 DOI: 10.1158/1541-7786.MCR-14-0121]
-
(2014)
Mol Cancer Res
, vol.12
, pp. 1254-1266
-
-
Berdiel-Acer, M.1
Cuadras, D.2
Díaz-Maroto, N.G.3
Sanjuan, X.4
Serrano, T.5
Berenguer, A.6
Moreno, V.7
Gonçalves-Ribeiro, S.8
Salazar, R.9
Villanueva, A.10
Molleví, D.G.11
-
101
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
PMID: 15549095
-
Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004; 432: 332-337 [PMID: 15549095 DOI: 10.1038/nature03096]
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
102
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
PMID: 14679171
-
Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112: 1776-1784 [PMID: 14679171 DOI: 10.1172/JCI20530]
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
103
-
-
0036595629
-
Epithelial-mesenchymal transitions in tumour progression
-
PMID: 12189386
-
Thiery JP. Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2002; 2: 442-454 [PMID: 12189386 DOI: 10.1038/nrc822]
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 442-454
-
-
Thiery, J.P.1
-
104
-
-
33749344520
-
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition
-
PMID: 17000670
-
Lee TK, Poon RT, Yuen AP, Ling MT, Kwok WK, Wang XH, Wong YC, Guan XY, Man K, Chau KL, Fan ST. Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition. Clin Cancer Res 2006; 12: 5369-5376 [PMID: 17000670 DOI: 10.1158/1078-0432.CCR-05-2722]
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5369-5376
-
-
Lee, T.K.1
Poon, R.T.2
Yuen, A.P.3
Ling, M.T.4
Kwok, W.K.5
Wang, X.H.6
Wong, Y.C.7
Guan, X.Y.8
Man, K.9
Chau, K.L.10
Fan, S.T.11
-
105
-
-
34248223535
-
A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis
-
PMID: 17409456
-
Alonso SR, Tracey L, Ortiz P, Pérez-Gómez B, Palacios J, Pollán M, Linares J, Serrano S, Sáez-Castillo AI, Sánchez L, Pajares R, Sánchez-Aguilera A, Artiga MJ, Piris MA, Rodríguez-Peralto JL. A high-throughput study in melanoma identifies epithelial-mesenchymal transition as a major determinant of metastasis. Cancer Res 2007; 67: 3450-3460 [PMID: 17409456 DOI: 10.1158/0008-5472.CAN-06-3481]
-
(2007)
Cancer Res
, vol.67
, pp. 3450-3460
-
-
Alonso, S.R.1
Tracey, L.2
Ortiz, P.3
Pérez-Gómez, B.4
Palacios, J.5
Pollán, M.6
Linares, J.7
Serrano, S.8
Sáez-Castillo, A.I.9
Sánchez, L.10
Pajares, R.11
Sánchez-Aguilera, A.12
Artiga, M.J.13
Piris, M.A.14
Rodríguez-Peralto, J.L.15
-
106
-
-
77951176116
-
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients
-
PMID: 20335658
-
Chen L, Chan TH, Yuan YF, Hu L, Huang J, Ma S, Wang J, Dong SS, Tang KH, Xie D, Li Y, Guan XY. CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. J Clin Invest 2010; 120: 1178-1191 [PMID: 20335658 DOI: 10.1172/JCI40665]
-
(2010)
J Clin Invest
, vol.120
, pp. 1178-1191
-
-
Chen, L.1
Chan, T.H.2
Yuan, Y.F.3
Hu, L.4
Huang, J.5
Ma, S.6
Wang, J.7
Dong, S.S.8
Tang, K.H.9
Xie, D.10
Li, Y.11
Guan, X.Y.12
-
107
-
-
0034331032
-
Cadherins in embryonic and neural morphogenesis
-
PMID: 11253370
-
Tepass U, Truong K, Godt D, Ikura M, Peifer M. Cadherins in embryonic and neural morphogenesis. Nat Rev Mol Cell Biol 2000; 1: 91-100 [PMID: 11253370 DOI: 10.1038/35040042]
-
(2000)
Nat Rev Mol Cell Biol
, vol.1
, pp. 91-100
-
-
Tepass, U.1
Truong, K.2
Godt, D.3
Ikura, M.4
Peifer, M.5
-
108
-
-
0344845003
-
Epithelial-mesenchymal transitions in development and pathologies
-
PMID: 14644200
-
Thiery JP . Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol 2003; 15: 740-746 [PMID: 14644200]
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 740-746
-
-
Thiery, J.P.1
-
109
-
-
78751544628
-
p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/ AKT/hypoxia-inducible factor-1α pathways
-
PMID: 21254169
-
Fu J, Chen Y, Cao J, Luo T, Qian YW, Yang W, Ren YB, Su B, Cao GW, Yang Y, Yan YQ, Shen F, Wu MC, Feng GS, Wang HY. p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/ AKT/hypoxia-inducible factor-1α pathways. Hepatology 2011; 53: 181-192 [PMID: 21254169 DOI: 10.1002/hep.24015]
-
(2011)
Hepatology
, vol.53
, pp. 181-192
-
-
Fu, J.1
Chen, Y.2
Cao, J.3
Luo, T.4
Qian, Y.W.5
Yang, W.6
Ren, Y.B.7
Su, B.8
Cao, G.W.9
Yang, Y.10
Yan, Y.Q.11
Shen, F.12
Wu, M.C.13
Feng, G.S.14
Wang, H.Y.15
-
110
-
-
8144228952
-
Friends or foes - bipolar effects of the tumour stroma in cancer
-
PMID: 15516957
-
Mueller MM, Fusenig NE. Friends or foes - bipolar effects of the tumour stroma in cancer. Nat Rev Cancer 2004; 4: 839-849 [PMID: 15516957 DOI: 10.1038/nrc1477]
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 839-849
-
-
Mueller, M.M.1
Fusenig, N.E.2
-
111
-
-
67651005404
-
EMT: When epithelial cells decide to become mesenchymal-like cells
-
PMID: 19487817
-
Kalluri R. EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest 2009; 119: 1417-1419 [PMID: 19487817 DOI: 10.1172/JCI39675]
-
(2009)
J Clin Invest
, vol.119
, pp. 1417-1419
-
-
Kalluri, R.1
-
112
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
PMID: 19945376
-
Thiery JP, Acloque H, Huang RY, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139: 871-890 [PMID: 19945376 DOI: 10.1016/j.cell.2009.11.007]
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
113
-
-
77953725777
-
Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: A pivotal role of CCL7
-
PMID: 19937793
-
Jung DW, Che ZM, Kim J, Kim K, Kim KY, Williams D, Kim J. Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7. Int J Cancer 2010; 127: 332-344 [PMID: 19937793 DOI: 10.1002/ijc.25060]
-
(2010)
Int J Cancer
, vol.127
, pp. 332-344
-
-
Jung, D.W.1
Che, Z.M.2
Kim, J.3
Kim, K.4
Kim, K.Y.5
Williams, D.6
Kim, J.7
-
114
-
-
0242499448
-
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
-
PMID: 14557817
-
Siegel PM, Massagué J. Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer 2003; 3: 807-821 [PMID: 14557817 DOI: 10.1038/nrc1208]
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 807-821
-
-
Siegel, P.M.1
Massagué, J.2
-
115
-
-
84893769522
-
Cancerassociated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
-
PMID: 24335925
-
Yu Y, Xiao CH, Tan LD, Wang QS, Li XQ, Feng YM. Cancerassociated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling. Br J Cancer 2014; 110: 724-732 [PMID: 24335925 DOI: 10.1038/bjc.2013.768]
-
(2014)
Br J Cancer
, vol.110
, pp. 724-732
-
-
Yu, Y.1
Xiao, C.H.2
Tan, L.D.3
Wang, Q.S.4
Li, X.Q.5
Feng, Y.M.6
-
116
-
-
0034785348
-
TGF-beta signaling in tumor suppression and cancer progression
-
PMID: 11586292
-
Derynck R, Akhurst RJ, Balmain A. TGF-beta signaling in tumor suppression and cancer progression. Nat Genet 2001; 29: 117-129 [PMID: 11586292 DOI: 10.1038/ng1001-117]
-
(2001)
Nat Genet
, vol.29
, pp. 117-129
-
-
Derynck, R.1
Akhurst, R.J.2
Balmain, A.3
-
117
-
-
78751523982
-
Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma
-
PMID: 21220499
-
Nagai T, Arao T, Furuta K, Sakai K, Kudo K, Kaneda H, Tamura D, Aomatsu K, Kimura H, Fujita Y, Matsumoto K, Saijo N, Kudo M, Nishio K. Sorafenib inhibits the hepatocyte growth factor-mediated epithelial mesenchymal transition in hepatocellular carcinoma. Mol Cancer Ther 2011; 10: 169-177 [PMID: 21220499 DOI: 10.1158/1535-7163.MCT-10-0544]
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 169-177
-
-
Nagai, T.1
Arao, T.2
Furuta, K.3
Sakai, K.4
Kudo, K.5
Kaneda, H.6
Tamura, D.7
Aomatsu, K.8
Kimura, H.9
Fujita, Y.10
Matsumoto, K.11
Saijo, N.12
Kudo, M.13
Nishio, K.14
-
118
-
-
77956904572
-
Cancerassociated fibroblasts enhance the gland-forming capability of prostate cancer stem cells
-
PMID: 20807814
-
Liao CP, Adisetiyo H, Liang M, Roy-Burman P. Cancerassociated fibroblasts enhance the gland-forming capability of prostate cancer stem cells. Cancer Res 2010; 70: 7294-7303 [PMID: 20807814 DOI: 10.1158/0008-5472.CAN-09-3982]
-
(2010)
Cancer Res
, vol.70
, pp. 7294-7303
-
-
Liao, C.P.1
Adisetiyo, H.2
Liang, M.3
Roy-Burman, P.4
-
119
-
-
67650996280
-
Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease
-
PMID: 19487820
-
Acloque H, Adams MS, Fishwick K, Bronner-Fraser M, Nieto MA. Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest 2009; 119: 1438-1449 [PMID: 19487820 DOI: 10.1172/JCI38019]
-
(2009)
J Clin Invest
, vol.119
, pp. 1438-1449
-
-
Acloque, H.1
Adams, M.S.2
Fishwick, K.3
Bronner-Fraser, M.4
Nieto, M.A.5
-
120
-
-
84894039409
-
miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts
-
PMID: 23924028
-
Gandellini P, Giannoni E, Casamichele A, Taddei ML, Callari M, Piovan C, Valdagni R, Pierotti MA, Zaffaroni N, Chiarugi P. miR-205 hinders the malignant interplay between prostate cancer cells and associated fibroblasts. Antioxid Redox Signal 2014; 20: 1045-1059 [PMID: 23924028 DOI: 10.1089/ars.2013.5292]
-
(2014)
Antioxid Redox Signal
, vol.20
, pp. 1045-1059
-
-
Gandellini, P.1
Giannoni, E.2
Casamichele, A.3
Taddei, M.L.4
Callari, M.5
Piovan, C.6
Valdagni, R.7
Pierotti, M.A.8
Zaffaroni, N.9
Chiarugi, P.10
-
121
-
-
41649102048
-
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer
-
PMID: 18250347
-
Liedtke C, Mazouni C, Hess KR, André F, Tordai A, Mejia JA, Symmans WF, Gonzalez-Angulo AM, Hennessy B, Green M, Cristofanilli M, Hortobagyi GN, Pusztai L. Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer. J Clin Oncol 2008; 26: 1275-1281 [PMID: 18250347 DOI: 10.1200/JCO.2007.14.4147]
-
(2008)
J Clin Oncol
, vol.26
, pp. 1275-1281
-
-
Liedtke, C.1
Mazouni, C.2
Hess, K.R.3
André, F.4
Tordai, A.5
Mejia, J.A.6
Symmans, W.F.7
Gonzalez-Angulo, A.M.8
Hennessy, B.9
Green, M.10
Cristofanilli, M.11
Hortobagyi, G.N.12
Pusztai, L.13
-
122
-
-
33847063053
-
The triple negative paradox: Primary tumor chemosensitivity of breast cancer subtypes
-
PMID: 17438091
-
Carey LA, Dees EC, Sawyer L, Gatti L, Moore DT, Collichio F, Ollila DW, Sartor CI, Graham ML, Perou CM. The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res 2007; 13: 2329-2334 [PMID: 17438091 DOI: 10.1158/1078-0432.CCR-06-1109]
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2329-2334
-
-
Carey, L.A.1
Dees, E.C.2
Sawyer, L.3
Gatti, L.4
Moore, D.T.5
Collichio, F.6
Ollila, D.W.7
Sartor, C.I.8
Graham, M.L.9
Perou, C.M.10
-
123
-
-
43049165453
-
The epithelialmesenchymal transition generates cells with properties of stem cells
-
PMID: 18485877
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA. The epithelialmesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-715 [PMID: 18485877 DOI: 10.1016/j.cell.2008.03.027]
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
124
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
PMID: 19262571
-
Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009; 9: 265-273 [PMID: 19262571 DOI: 10.1038/nrc2620]
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
125
-
-
42349091268
-
Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes
-
PMID: 18413739
-
Hawsawi NM, Ghebeh H, Hendrayani SF, Tulbah A, Al-Eid M, Al-Tweigeri T, Ajarim D, Alaiya A, Dermime S, Aboussekhra A. Breast carcinoma-associated fibroblasts and their counterparts display neoplastic-specific changes. Cancer Res 2008; 68: 2717-2725 [PMID: 18413739 DOI: 10.1158/0008-5472.CAN-08-0192]
-
(2008)
Cancer Res
, vol.68
, pp. 2717-2725
-
-
Hawsawi, N.M.1
Ghebeh, H.2
Hendrayani, S.F.3
Tulbah, A.4
Al-Eid, M.5
Al-Tweigeri, T.6
Ajarim, D.7
Alaiya, A.8
Dermime, S.9
Aboussekhra, A.10
-
126
-
-
33745837774
-
Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
-
PMID: 16794736
-
Loeffler M, Krüger JA, Niethammer AG, Reisfeld RA. Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J Clin Invest 2006; 116: 1955-1962 [PMID: 16794736 DOI: 10.1172/JCI26532]
-
(2006)
J Clin Invest
, vol.116
, pp. 1955-1962
-
-
Loeffler, M.1
Krüger, J.A.2
Niethammer, A.G.3
Reisfeld, R.A.4
-
127
-
-
57849106330
-
PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment
-
PMID: 19111878
-
Crawford Y, Kasman I, Yu L, Zhong C, Wu X, Modrusan Z, Kaminker J, Ferrara N. PDGF-C mediates the angiogenic and tumorigenic properties of fibroblasts associated with tumors refractory to anti-VEGF treatment. Cancer Cell 2009; 15: 21-34 [PMID: 19111878 DOI: 10.1016/j.ccr.2008.12.004]
-
(2009)
Cancer Cell
, vol.15
, pp. 21-34
-
-
Crawford, Y.1
Kasman, I.2
Yu, L.3
Zhong, C.4
Wu, X.5
Modrusan, Z.6
Kaminker, J.7
Ferrara, N.8
-
128
-
-
58149269348
-
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
-
PMID: 19122641
-
Kim S, Takahashi H, Lin WW, Descargues P, Grivennikov S, Kim Y, Luo JL, Karin M. Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. Nature 2009; 457: 102-106 [PMID: 19122641 DOI: 10.1038/nature07623]
-
(2009)
Nature
, vol.457
, pp. 102-106
-
-
Kim, S.1
Takahashi, H.2
Lin, W.W.3
Descargues, P.4
Grivennikov, S.5
Kim, Y.6
Luo, J.L.7
Karin, M.8
-
129
-
-
77954233120
-
Responsiveness of stromal fibroblasts to IFN-gamma blocks tumor growth via angiostasis
-
PMID: 19841170
-
Lu Y, Yang W, Qin C, Zhang L, Deng J, Liu S, Qin Z. Responsiveness of stromal fibroblasts to IFN-gamma blocks tumor growth via angiostasis. J Immunol 2009; 183: 6413-6421 [PMID: 19841170 DOI: 10.4049/jimmunol.0901073]
-
(2009)
J Immunol
, vol.183
, pp. 6413-6421
-
-
Lu, Y.1
Yang, W.2
Qin, C.3
Zhang, L.4
Deng, J.5
Liu, S.6
Qin, Z.7
-
130
-
-
16844386886
-
Plasminogen activation and cancer
-
PMID: 15841311
-
Danø K, Behrendt N, Høyer-Hansen G, Johnsen M, Lund LR, Ploug M, Rømer J. Plasminogen activation and cancer. Thromb Haemost 2005; 93: 676-681 [PMID: 15841311 DOI: 10.1267/THRO05040676]
-
(2005)
Thromb Haemost
, vol.93
, pp. 676-681
-
-
Dano, K.1
Behrendt, N.2
Hoyer-Hansen, G.3
Johnsen, M.4
Lund, L.R.5
Ploug, M.6
Romer, J.7
-
131
-
-
79954657385
-
Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma
-
PMID: 21145847
-
Kuang DM, Zhao Q, Wu Y, Peng C, Wang J, Xu Z, Yin XY, Zheng L. Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma. J Hepatol 2011; 54: 948-955 [PMID: 21145847 DOI: 10.1016/j.jhep.2010.08.041]
-
(2011)
J Hepatol
, vol.54
, pp. 948-955
-
-
Kuang, D.M.1
Zhao, Q.2
Wu, Y.3
Peng, C.4
Wang, J.5
Xu, Z.6
Yin, X.Y.7
Zheng, L.8
-
132
-
-
34247597310
-
Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells
-
PMID: 17442937
-
Nazareth MR, Broderick L, Simpson-Abelson MR, Kelleher RJ, Yokota SJ, Bankert RB. Characterization of human lung tumor-associated fibroblasts and their ability to modulate the activation of tumor-associated T cells. J Immunol 2007; 178: 5552-5562 [PMID: 17442937]
-
(2007)
J Immunol
, vol.178
, pp. 5552-5562
-
-
Nazareth, M.R.1
Broderick, L.2
Simpson-Abelson, M.R.3
Kelleher, R.J.4
Yokota, S.J.5
Bankert, R.B.6
-
133
-
-
77949329050
-
Tumor microenvironments direct the recruitment and expansion of human Th17 cells
-
PMID: 20026736
-
Su X, Ye J, Hsueh EC, Zhang Y, Hoft DF, Peng G. Tumor microenvironments direct the recruitment and expansion of human Th17 cells. J Immunol 2010; 184: 1630-1641 [PMID: 20026736 DOI: 10.4049/jimmunol.0902813]
-
(2010)
J Immunol
, vol.184
, pp. 1630-1641
-
-
Su, X.1
Ye, J.2
Hsueh, E.C.3
Zhang, Y.4
Hoft, D.F.5
Peng, G.6
-
134
-
-
78049399458
-
Reciprocal functional modulation of the activation of T lymphocytes and fibroblasts derived from human solid tumors
-
PMID: 20686130
-
Barnas JL, Simpson-Abelson MR, Brooks SP, Kelleher RJ, Bankert RB. Reciprocal functional modulation of the activation of T lymphocytes and fibroblasts derived from human solid tumors. J Immunol 2010; 185: 2681-2692 [PMID: 20686130 DOI: 10.4049/jimmunol.1000896]
-
(2010)
J Immunol
, vol.185
, pp. 2681-2692
-
-
Barnas, J.L.1
Simpson-Abelson, M.R.2
Brooks, S.P.3
Kelleher, R.J.4
Bankert, R.B.5
-
135
-
-
18444408375
-
COX-2: A molecular target for colorectal cancer prevention
-
PMID: 15837998
-
Brown JR, DuBois RN. COX-2: a molecular target for colorectal cancer prevention. J Clin Oncol 2005; 23: 2840-2855 [PMID: 15837998 DOI: 10.1200/JCO.2005.09.051]
-
(2005)
J Clin Oncol
, vol.23
, pp. 2840-2855
-
-
Brown, J.R.1
DuBois, R.N.2
-
136
-
-
73949125660
-
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
-
PMID: 19934056
-
Balsamo M, Scordamaglia F, Pietra G, Manzini C, Cantoni C, Boitano M, Queirolo P, Vermi W, Facchetti F, Moretta A, Moretta L, Mingari MC, Vitale M. Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity. Proc Natl Acad Sci USA 2009; 106: 20847-20852 [PMID: 19934056 DOI: 10.1073/pnas.0906481106]
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 20847-20852
-
-
Balsamo, M.1
Scordamaglia, F.2
Pietra, G.3
Manzini, C.4
Cantoni, C.5
Boitano, M.6
Queirolo, P.7
Vermi, W.8
Facchetti, F.9
Moretta, A.10
Moretta, L.11
Mingari, M.C.12
Vitale, M.13
-
137
-
-
84858153171
-
Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO
-
PMID: 22182446
-
Li T, Yang Y, Hua X, Wang G, Liu W, Jia C, Tai Y, Zhang Q, Chen G. Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO. Cancer Lett 2012; 318: 154-161 [PMID: 22182446 DOI: 10.1016/j.canlet.2011.12.020]
-
(2012)
Cancer Lett
, vol.318
, pp. 154-161
-
-
Li, T.1
Yang, Y.2
Hua, X.3
Wang, G.4
Liu, W.5
Jia, C.6
Tai, Y.7
Zhang, Q.8
Chen, G.9
-
138
-
-
34250189539
-
Clinical implications of fibroblast activation protein in patients with colon cancer
-
PMID: 17363526
-
Henry LR, Lee HO, Lee JS, Klein-Szanto A, Watts P, Ross EA, Chen WT, Cheng JD. Clinical implications of fibroblast activation protein in patients with colon cancer. Clin Cancer Res 2007; 13: 1736-1741 [PMID: 17363526 DOI: 10.1158/1078-0432.CCR-06-1746]
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1736-1741
-
-
Henry, L.R.1
Lee, H.O.2
Lee, J.S.3
Klein-Szanto, A.4
Watts, P.5
Ross, E.A.6
Chen, W.T.7
Cheng, J.D.8
-
139
-
-
84880182893
-
Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity
-
PMID: 23873014
-
Li T, Yi S, Liu W, Jia C, Wang G, Hua X, Tai Y, Zhang Q, Chen G. Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity. Med Oncol 2013; 30: 663 [PMID: 23873014 DOI: 10.1007/s12032-013-0663-z]
-
(2013)
Med Oncol
, vol.30
, pp. 663
-
-
Li, T.1
Yi, S.2
Liu, W.3
Jia, C.4
Wang, G.5
Hua, X.6
Tai, Y.7
Zhang, Q.8
Chen, G.9
-
140
-
-
70449636444
-
Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge
-
PMID: 19718050
-
van Zijl F, Mair M, Csiszar A, Schneller D, Zulehner G, Huber H, Eferl R, Beug H, Dolznig H, Mikulits W. Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge. Oncogene 2009; 28: 4022-4033 [PMID: 19718050 DOI: 10.1038/onc.2009.253]
-
(2009)
Oncogene
, vol.28
, pp. 4022-4033
-
-
Van Zijl, F.1
Mair, M.2
Csiszar, A.3
Schneller, D.4
Zulehner, G.5
Huber, H.6
Eferl, R.7
Beug, H.8
Dolznig, H.9
Mikulits, W.10
-
141
-
-
78651233786
-
Amelioration of hepatic fibrosis by NK cell activation
-
PMID: 20660699
-
Muhanna N, Abu Tair L, Doron S, Amer J, Azzeh M, Mahamid M, Friedman S, Safadi R. Amelioration of hepatic fibrosis by NK cell activation. Gut 2011; 60: 90-98 [PMID: 20660699 DOI: 10.1136/gut.2010.211136]
-
(2011)
Gut
, vol.60
, pp. 90-98
-
-
Muhanna, N.1
Abu Tair, L.2
Doron, S.3
Amer, J.4
Azzeh, M.5
Mahamid, M.6
Friedman, S.7
Safadi, R.8
-
142
-
-
73449111925
-
Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells
-
PMID: 19902483
-
Kuang DM, Peng C, Zhao Q, Wu Y, Chen MS, Zheng L. Activated monocytes in peritumoral stroma of hepatocellular carcinoma promote expansion of memory T helper 17 cells. Hepatology 2010; 51: 154-164 [PMID: 19902483 DOI: 10.1002/hep.23291]
-
(2010)
Hepatology
, vol.51
, pp. 154-164
-
-
Kuang, D.M.1
Peng, C.2
Zhao, Q.3
Wu, Y.4
Chen, M.S.5
Zheng, L.6
-
143
-
-
84871592878
-
The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: Validation in the VICTOR trial
-
PMID: 22865778
-
Huijbers A, Tollenaar RA, v Pelt GW, Zeestraten EC, Dutton S, McConkey CC, Domingo E, Smit VT, Midgley R, Warren BF, Johnstone EC, Kerr DJ, Mesker WE. The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial. Ann Oncol 2013; 24: 179-185 [PMID: 22865778 DOI: 10.1093/annonc/mds246]
-
(2013)
Ann Oncol
, vol.24
, pp. 179-185
-
-
Huijbers, A.1
Tollenaar, R.A.2
Pelt, V.G.W.3
Zeestraten, E.C.4
Dutton, S.5
McConkey, C.C.6
Domingo, E.7
Smit, V.T.8
Midgley, R.9
Warren, B.F.10
Johnstone, E.C.11
Kerr, D.J.12
Mesker, W.E.13
-
144
-
-
0035915797
-
Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast
-
PMID: 11241314
-
Ariga N, Sato E, Ohuchi N, Nagura H, Ohtani H. Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast. Int J Cancer 2001; 95: 67-72 [PMID: 11241314]
-
(2001)
Int J Cancer
, vol.95
, pp. 67-72
-
-
Ariga, N.1
Sato, E.2
Ohuchi, N.3
Nagura, H.4
Ohtani, H.5
-
145
-
-
38849106118
-
Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma
-
PMID: 17962206
-
Porta C, De Amici M, Quaglini S, Paglino C, Tagliani F, Boncimino A, Moratti R, Corazza GR. Circulating interleukin-6 as a tumor marker for hepatocellular carcinoma. Ann Oncol 2008; 19: 353-358 [PMID: 17962206 DOI: 10.1093/annonc/mdm448]
-
(2008)
Ann Oncol
, vol.19
, pp. 353-358
-
-
Porta, C.1
De Amici, M.2
Quaglini, S.3
Paglino, C.4
Tagliani, F.5
Boncimino, A.6
Moratti, R.7
Corazza, G.R.8
-
146
-
-
75849116069
-
Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?
-
PMID: 19840860
-
Gonda TA, Varro A, Wang TC, Tycko B. Molecular biology of cancer-associated fibroblasts: can these cells be targeted in anti-cancer therapy? Semin Cell Dev Biol 2010; 21: 2-10 [PMID: 19840860 DOI: 10.1016/j.semcdb.2009.10.001]
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 2-10
-
-
Gonda, T.A.1
Varro, A.2
Wang, T.C.3
Tycko, B.4
-
147
-
-
0037102412
-
Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model
-
PMID: 12183436
-
Cheng JD, Dunbrack RL, Valianou M, Rogatko A, Alpaugh RK, Weiner LM. Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model. Cancer Res 2002; 62: 4767-4772 [PMID: 12183436]
-
(2002)
Cancer Res
, vol.62
, pp. 4767-4772
-
-
Cheng, J.D.1
Dunbrack, R.L.2
Valianou, M.3
Rogatko, A.4
Alpaugh, R.K.5
Weiner, L.M.6
-
148
-
-
47349084576
-
Progress in the development of matrix metalloproteinase inhibitors
-
PMID: 18537616
-
Tu G, Xu W, Huang H, Li S. Progress in the development of matrix metalloproteinase inhibitors. Curr Med Chem 2008; 15: 1388-1395 [PMID: 18537616]
-
(2008)
Curr Med Chem
, vol.15
, pp. 1388-1395
-
-
Tu, G.1
Xu, W.2
Huang, H.3
Li, S.4
-
149
-
-
77954899030
-
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
PMID: 20516446
-
Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, Stankevich E, Pons A, Salay TM, McMiller TL, Gilson MM, Wang C, Selby M, Taube JM, Anders R, Chen L, Korman AJ, Pardoll DM, Lowy I, Topalian SL. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010; 28: 3167-3175 [PMID: 20516446 DOI: 10.1200/JCO.2009.26.7609]
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
Stankevich, E.7
Pons, A.8
Salay, T.M.9
McMiller, T.L.10
Gilson, M.M.11
Wang, C.12
Selby, M.13
Taube, J.M.14
Anders, R.15
Chen, L.16
Korman, A.J.17
Pardoll, D.M.18
Lowy, I.19
Topalian, S.L.20
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