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Volumn 145, Issue 1, 2013, Pages

Progastrin-induced secretion of insulin-like growth factor 2 from colonic myofibroblasts stimulates colonic epithelial proliferation in mice

Author keywords

Colon Cancer; Mouse Model; PI3K; PKC

Indexed keywords

3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; ALPHA SMOOTH MUSCLE ACTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROGASTRIN; PROTEIN KINASE C; SOMATOMEDIN B; VIMENTIN;

EID: 84879483263     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2013.03.012     Document Type: Article
Times cited : (25)

References (42)
  • 1
    • 67651159312 scopus 로고    scopus 로고
    • Stem cells, self-renewal, and differentiation in the intestinal epithelium
    • L.G. van der Flier, and H. Clevers Stem cells, self-renewal, and differentiation in the intestinal epithelium Annu Rev Physiol 71 2009 241 260
    • (2009) Annu Rev Physiol , vol.71 , pp. 241-260
    • Van Der Flier, L.G.1    Clevers, H.2
  • 2
    • 23244448347 scopus 로고    scopus 로고
    • Expression pattern of Wnt signaling components in the adult intestine
    • A. Gregorieff, D. Pinto, and H. Begthel Expression pattern of Wnt signaling components in the adult intestine Gastroenterology 129 2005 626 638
    • (2005) Gastroenterology , vol.129 , pp. 626-638
    • Gregorieff, A.1    Pinto, D.2    Begthel, H.3
  • 3
    • 21744453780 scopus 로고    scopus 로고
    • Epithelial cells and their neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer
    • D.W. Powell, P.A. Adegboyega, and J.F. Di Mari Epithelial cells and their neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer Am J Physiol Gastrointest Liver Physiol 289 2005 G2 G7
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289
    • Powell, D.W.1    Adegboyega, P.A.2    Di Mari, J.F.3
  • 4
    • 0035043972 scopus 로고    scopus 로고
    • The gastrins: Their production and biological activities
    • G.J. Dockray, A. Varro, and R. Dimaline The gastrins: their production and biological activities Annu Rev Physiol 63 2001 119 139
    • (2001) Annu Rev Physiol , vol.63 , pp. 119-139
    • Dockray, G.J.1    Varro, A.2    Dimaline, R.3
  • 5
    • 0027196982 scopus 로고
    • Expression of the gastrin gene in the normal human colon and colorectal adenocarcinoma
    • G.G. Finley, R.A. Koski, and M.F. Melhem Expression of the gastrin gene in the normal human colon and colorectal adenocarcinoma Cancer Res 53 1993 2919 2926
    • (1993) Cancer Res , vol.53 , pp. 2919-2926
    • Finley, G.G.1    Koski, R.A.2    Melhem, M.F.3
  • 6
    • 0028982966 scopus 로고
    • Expression, processing, and secretion of gastrin in patients with colorectal carcinoma
    • G.D. Ciccotosto, A. McLeish, and K.J. Hardy Expression, processing, and secretion of gastrin in patients with colorectal carcinoma Gastroenterology 109 1995 1142 1153
    • (1995) Gastroenterology , vol.109 , pp. 1142-1153
    • Ciccotosto, G.D.1    McLeish, A.2    Hardy, K.J.3
  • 7
    • 0027391418 scopus 로고
    • Identification of progastrin derived peptides in colorectal carcinoma extracts
    • J. Nemeth, B. Taylor, and S. Pauwels Identification of progastrin derived peptides in colorectal carcinoma extracts Gut 34 1993 90 95
    • (1993) Gut , vol.34 , pp. 90-95
    • Nemeth, J.1    Taylor, B.2    Pauwels, S.3
  • 8
    • 0027480995 scopus 로고
    • Expression but incomplete maturation of progastrin in colorectal carcinomas
    • W.W. van Solinge, F.C. Nielsen, and L. Friis-Hansen Expression but incomplete maturation of progastrin in colorectal carcinomas Gastroenterology 104 1993 1099 1107
    • (1993) Gastroenterology , vol.104 , pp. 1099-1107
    • Van Solinge, W.W.1    Nielsen, F.C.2    Friis-Hansen, L.3
  • 9
    • 0035173783 scopus 로고    scopus 로고
    • Plasma levels of progastrin but not amidated gastrin or glycine extended gastrin are elevated in patients with colorectal carcinoma
    • R.K. Siddheshwar, J.C. Gray, and S.B. Kelly Plasma levels of progastrin but not amidated gastrin or glycine extended gastrin are elevated in patients with colorectal carcinoma Gut 48 2001 47 52
    • (2001) Gut , vol.48 , pp. 47-52
    • Siddheshwar, R.K.1    Gray, J.C.2    Kelly, S.B.3
  • 10
    • 0030862410 scopus 로고    scopus 로고
    • Glycine-extended gastrin acts as an autocrine growth factor in a nontransformed colon cell line
    • F. Hollande, A. Imdahl, and T. Mantamadiotis Glycine-extended gastrin acts as an autocrine growth factor in a nontransformed colon cell line Gastroenterology 113 1997 1576 1588
    • (1997) Gastroenterology , vol.113 , pp. 1576-1588
    • Hollande, F.1    Imdahl, A.2    Mantamadiotis, T.3
  • 11
    • 0028042208 scopus 로고
    • Incomplete processing of progastrin expressed by human colon cancer cells: Role of noncarboxyamidated gastrins
    • P. Singh, Z. Xu, and B. Dai Incomplete processing of progastrin expressed by human colon cancer cells: role of noncarboxyamidated gastrins Am J Physiol 266 1994 G459 G468
    • (1994) Am J Physiol , vol.266
    • Singh, P.1    Xu, Z.2    Dai, B.3
  • 12
    • 0029861301 scopus 로고    scopus 로고
    • Processing and proliferative effects of human progastrin in transgenic mice
    • T.C. Wang, T.J. Koh, and A. Varro Processing and proliferative effects of human progastrin in transgenic mice J Clin Invest 98 1996 1918 1929
    • (1996) J Clin Invest , vol.98 , pp. 1918-1929
    • Wang, T.C.1    Koh, T.J.2    Varro, A.3
  • 13
    • 0037960176 scopus 로고    scopus 로고
    • Progastrin stimulates murine colonic epithelial mitosis after DNA damage
    • P.D. Ottewell, A.J. Watson, and T.C. Wang Progastrin stimulates murine colonic epithelial mitosis after DNA damage Gastroenterology 124 2003 1348 1357
    • (2003) Gastroenterology , vol.124 , pp. 1348-1357
    • Ottewell, P.D.1    Watson, A.J.2    Wang, T.C.3
  • 14
    • 20144388992 scopus 로고    scopus 로고
    • Signaling pathways associated with colonic mucosa hyperproliferation in mice overexpressing gastrin precursors
    • A. Ferrand, C. Bertrand, and G. Portolan Signaling pathways associated with colonic mucosa hyperproliferation in mice overexpressing gastrin precursors Cancer Res 65 2005 2770 2777
    • (2005) Cancer Res , vol.65 , pp. 2770-2777
    • Ferrand, A.1    Bertrand, C.2    Portolan, G.3
  • 15
    • 84860165742 scopus 로고    scopus 로고
    • P53 gene mutation increases progastrin dependent colonic proliferation and colon cancer formation in mice
    • V. Ramanathan, G. Jin, and C.B. Westphalen P53 gene mutation increases progastrin dependent colonic proliferation and colon cancer formation in mice Cancer Invest 30 2012 275 286
    • (2012) Cancer Invest , vol.30 , pp. 275-286
    • Ramanathan, V.1    Jin, G.2    Westphalen, C.B.3
  • 16
    • 0034235903 scopus 로고    scopus 로고
    • Progastrin expression predisposes mice to colon carcinomas and adenomas in response to a chemical carcinogen
    • P. Singh, M. Velasco, and R. Given Progastrin expression predisposes mice to colon carcinomas and adenomas in response to a chemical carcinogen Gastroenterology 119 2000 162 171
    • (2000) Gastroenterology , vol.119 , pp. 162-171
    • Singh, P.1    Velasco, M.2    Given, R.3
  • 17
    • 56249109723 scopus 로고    scopus 로고
    • Flow cytometric detection of progastrin interaction with gastrointestinal cells
    • A. Dubeykovskiy, T. Nguyen, and Z. Dubeykovskaya Flow cytometric detection of progastrin interaction with gastrointestinal cells Regul Pept 151 2008 106 114
    • (2008) Regul Pept , vol.151 , pp. 106-114
    • Dubeykovskiy, A.1    Nguyen, T.2    Dubeykovskaya, Z.3
  • 18
    • 84862732998 scopus 로고    scopus 로고
    • Igf2bp1 is required for full induction of Ptgs2 mRNA in colonic mesenchymal stem cells in mice
    • N.A. Manieri, M.R. Drylewicz, and H. Miyoshi Igf2bp1 is required for full induction of Ptgs2 mRNA in colonic mesenchymal stem cells in mice Gastroenterology 143 2012 110 121
    • (2012) Gastroenterology , vol.143 , pp. 110-121
    • Manieri, N.A.1    Drylewicz, M.R.2    Miyoshi, H.3
  • 19
    • 0036107819 scopus 로고    scopus 로고
    • Gastrin-cholecystokinin(B) receptor expression in AGS cells is associated with direct inhibition and indirect stimulation of cell proliferation via paracrine activation of the epidermal growth factor receptor
    • A. Varro, P.J. Noble, and L.E. Wroblewski Gastrin-cholecystokinin(B) receptor expression in AGS cells is associated with direct inhibition and indirect stimulation of cell proliferation via paracrine activation of the epidermal growth factor receptor Gut 50 2002 827 833
    • (2002) Gut , vol.50 , pp. 827-833
    • Varro, A.1    Noble, P.J.2    Wroblewski, L.E.3
  • 20
    • 0037951750 scopus 로고    scopus 로고
    • Oncogenic ras induces gastrin/CCKB receptor gene expression in human colon cancer cell lines LoVo and Colo320HSR
    • H. Hori, H. Nakata, and G. Iguchi Oncogenic ras induces gastrin/CCKB receptor gene expression in human colon cancer cell lines LoVo and Colo320HSR J Lab Clin Med 141 2003 335 341
    • (2003) J Lab Clin Med , vol.141 , pp. 335-341
    • Hori, H.1    Nakata, H.2    Iguchi, G.3
  • 21
    • 0025949439 scopus 로고
    • A low-temperature method for the isolation of small-intestinal epithelium along the crypt-villus axis
    • N. Flint, F.L. Cove, and G.S. Evans A low-temperature method for the isolation of small-intestinal epithelium along the crypt-villus axis Biochem J 280 1991 331 334
    • (1991) Biochem J , vol.280 , pp. 331-334
    • Flint, N.1    Cove, F.L.2    Evans, G.S.3
  • 22
    • 0025136859 scopus 로고
    • The temporal and spatial changes in cell proliferation within the irradiated crypts of the murine small intestine
    • C.S. Potten, G. Owen, and S.A. Roberts The temporal and spatial changes in cell proliferation within the irradiated crypts of the murine small intestine Int J Radiat Biol 57 1990 185 199
    • (1990) Int J Radiat Biol , vol.57 , pp. 185-199
    • Potten, C.S.1    Owen, G.2    Roberts, S.A.3
  • 23
    • 70349207207 scopus 로고    scopus 로고
    • Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice
    • G. Jin, V. Ramanathan, and M. Quante Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice J Clin Invest 119 2009 2691 2701
    • (2009) J Clin Invest , vol.119 , pp. 2691-2701
    • Jin, G.1    Ramanathan, V.2    Quante, M.3
  • 24
    • 23844509794 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-5 is a target of matrix metalloproteinase-7: Implications for epithelial-mesenchymal signaling
    • E. Hemers, C. Duval, and C. McCaig Insulin-like growth factor binding protein-5 is a target of matrix metalloproteinase-7: implications for epithelial-mesenchymal signaling Cancer Res 65 2005 7363 7369
    • (2005) Cancer Res , vol.65 , pp. 7363-7369
    • Hemers, E.1    Duval, C.2    McCaig, C.3
  • 25
    • 0026538194 scopus 로고
    • Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor alpha
    • H. Lahm, L. Suardet, and P.L. Laurent Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor alpha Br J Cancer 65 1992 341 346
    • (1992) Br J Cancer , vol.65 , pp. 341-346
    • Lahm, H.1    Suardet, L.2    Laurent, P.L.3
  • 26
    • 0034110139 scopus 로고    scopus 로고
    • Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers
    • K. Szepeshazi, A.V. Schally, and K. Groot Antagonists of growth hormone-releasing hormone (GH-RH) inhibit IGF-II production and growth of HT-29 human colon cancers Br J Cancer 82 2000 1724 1731
    • (2000) Br J Cancer , vol.82 , pp. 1724-1731
    • Szepeshazi, K.1    Schally, A.V.2    Groot, K.3
  • 27
    • 9144223082 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitor AG1024 exerts antileukaemic effects on STI571-resistant Bcr-Abl expressing cells and decreases AKT phosphorylation
    • E. Deutsch, L. Maggiorella, and B. Wen Tyrosine kinase inhibitor AG1024 exerts antileukaemic effects on STI571-resistant Bcr-Abl expressing cells and decreases AKT phosphorylation Br J Cancer 91 2004 1735 1741
    • (2004) Br J Cancer , vol.91 , pp. 1735-1741
    • Deutsch, E.1    Maggiorella, L.2    Wen, B.3
  • 28
    • 65349189620 scopus 로고    scopus 로고
    • KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract
    • H. Zheng, D.M. Pritchard, and X. Yang KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract Am J Physiol Gastrointest Liver Physiol 296 2009 G490 G498
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296
    • Zheng, H.1    Pritchard, D.M.2    Yang, X.3
  • 29
    • 78649815108 scopus 로고    scopus 로고
    • The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway
    • O. Patel, K.M. Marshall, and G. Bramante The C-terminal flanking peptide (CTFP) of progastrin inhibits apoptosis via a PI3-kinase-dependent pathway Regul Pept 165 2010 224 231
    • (2010) Regul Pept , vol.165 , pp. 224-231
    • Patel, O.1    Marshall, K.M.2    Bramante, G.3
  • 30
    • 34547621429 scopus 로고    scopus 로고
    • Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B
    • W. Rengifo-Cam, S. Umar, and S. Sarkar Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B Cancer Res 67 2007 7266 7274
    • (2007) Cancer Res , vol.67 , pp. 7266-7274
    • Rengifo-Cam, W.1    Umar, S.2    Sarkar, S.3
  • 31
    • 0035896536 scopus 로고    scopus 로고
    • Biologically active recombinant human progastrin(6-80) contains a tightly bound calcium ion
    • G.S. Baldwin, F. Hollande, and Z. Yang Biologically active recombinant human progastrin(6-80) contains a tightly bound calcium ion J Biol Chem 276 2001 7791 7796
    • (2001) J Biol Chem , vol.276 , pp. 7791-7796
    • Baldwin, G.S.1    Hollande, F.2    Yang, Z.3
  • 32
    • 79251550135 scopus 로고    scopus 로고
    • Annexin A2 mediates up-regulation of NF-kappaB, beta-catenin, and stem cell in response to progastrin in mice and HEK-293 cells
    • S. Sarkar, R. Swiercz, and C. Kantara Annexin A2 mediates up-regulation of NF-kappaB, beta-catenin, and stem cell in response to progastrin in mice and HEK-293 cells Gastroenterology 140 2011 583 595
    • (2011) Gastroenterology , vol.140 , pp. 583-595
    • Sarkar, S.1    Swiercz, R.2    Kantara, C.3
  • 33
    • 84859473727 scopus 로고    scopus 로고
    • Clathrin mediates endocytosis of progastrin and activates MAPKs: Role of cell surface annexin A2
    • S. Sarkar, C. Kantara, and P. Singh Clathrin mediates endocytosis of progastrin and activates MAPKs: role of cell surface annexin A2 Am J Physiol Gastrointest Liver Physiol 302 2012 G712 G722
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.302
    • Sarkar, S.1    Kantara, C.2    Singh, P.3
  • 34
    • 77954378961 scopus 로고    scopus 로고
    • Stimulation of proliferation in the colorectal mucosa by gastrin precursors is blocked by desferrioxamine
    • A. Ferrand, S. Lachal, and G. Bramante Stimulation of proliferation in the colorectal mucosa by gastrin precursors is blocked by desferrioxamine Am J Physiol Gastrointest Liver Physiol 299 2010 G220 G227
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299
    • Ferrand, A.1    Lachal, S.2    Bramante, G.3
  • 35
    • 0037307028 scopus 로고    scopus 로고
    • Progastrin1-80 stimulates growth of intestinal epithelial cells in vitro via high-affinity binding sites
    • P. Singh, X. Lu, and S. Cobb Progastrin1-80 stimulates growth of intestinal epithelial cells in vitro via high-affinity binding sites Am J Physiol Gastrointest Liver Physiol 284 2003 G328 G339
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.284
    • Singh, P.1    Lu, X.2    Cobb, S.3
  • 36
    • 33646350741 scopus 로고    scopus 로고
    • The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pylori
    • C. McCaig, C. Duval, and E. Hemers The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pylori Gastroenterology 130 2006 1754 1763
    • (2006) Gastroenterology , vol.130 , pp. 1754-1763
    • McCaig, C.1    Duval, C.2    Hemers, E.3
  • 37
    • 0036905115 scopus 로고    scopus 로고
    • Cellular actions of the insulin-like growth factor binding proteins
    • S.M. Firth, and R.C. Baxter Cellular actions of the insulin-like growth factor binding proteins Endocr Rev 23 2002 824 854
    • (2002) Endocr Rev , vol.23 , pp. 824-854
    • Firth, S.M.1    Baxter, R.C.2
  • 38
    • 9744231436 scopus 로고    scopus 로고
    • Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis
    • K. Nosho, H. Yamamoto, and H. Taniguchi Interplay of insulin-like growth factor-II, insulin-like growth factor-I, insulin-like growth factor-I receptor, COX-2, and matrix metalloproteinase-7, play key roles in the early stage of colorectal carcinogenesis Clin Cancer Res 10 2004 7950 7957
    • (2004) Clin Cancer Res , vol.10 , pp. 7950-7957
    • Nosho, K.1    Yamamoto, H.2    Taniguchi, H.3
  • 39
    • 0037051707 scopus 로고    scopus 로고
    • Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of forkhead1, initially mitogenic, then mediating growth arrest and differentiation
    • D.Z. Ewton, S. Kansra, and S. Lim Insulin-like growth factor-I has a biphasic effect on colon carcinoma cells through transient inactivation of forkhead1, initially mitogenic, then mediating growth arrest and differentiation Int J Cancer 98 2002 665 673
    • (2002) Int J Cancer , vol.98 , pp. 665-673
    • Ewton, D.Z.1    Kansra, S.2    Lim, S.3
  • 40
    • 40149098552 scopus 로고    scopus 로고
    • Growth inhibition of insulin-like growth factor i receptor monoclonal antibody to human colorectal cancer cells
    • Y. Zhang, and Y. Zhang Growth inhibition of insulin-like growth factor I receptor monoclonal antibody to human colorectal cancer cells Cancer Invest 26 2008 230 236
    • (2008) Cancer Invest , vol.26 , pp. 230-236
    • Zhang, Y.1    Zhang, Y.2
  • 41
    • 7044284840 scopus 로고    scopus 로고
    • A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations
    • S.T. Magness, R. Bataller, and L. Yang A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations Hepatology 40 2004 1151 1159
    • (2004) Hepatology , vol.40 , pp. 1151-1159
    • Magness, S.T.1    Bataller, R.2    Yang, L.3
  • 42
    • 84862933577 scopus 로고    scopus 로고
    • In vivo fate mapping identifies mesenchymal progenitor cells
    • D. Grcevic, S. Pejda, and B.G. Matthews In vivo fate mapping identifies mesenchymal progenitor cells Stem Cells 30 2012 187 196
    • (2012) Stem Cells , vol.30 , pp. 187-196
    • Grcevic, D.1    Pejda, S.2    Matthews, B.G.3


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