The invasive potential of human melanoma cell lines correlates with their ability to alter fibroblast gene expression in vitro and the stromal microenvironment in vivo

International Journal of Cancer

Volumn 125, Issue 8, 2009, Pages 1796-1804

  Li, Ling ^a   Dragulev, Bojan ^a   Zigrino, Paola ^b   Mauch, Cornelia ^b   Fox, Jay W ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Gene expression; IL 1B; Invasion; Melanoma; Metastasis; Microenvironment; Stroma

Indexed keywords

CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; SMALL INTERFERING RNA; CYTOKINE; MESSENGER RNA;

ARTICLE; CANCER INVASION; CELL INFILTRATION; CELL STIMULATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MACROPHAGE; MELANOMA; MELANOMA CELL; METASTASIS; MICROENVIRONMENT; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; QUANTITATIVE GENETICS; REAL TIME POLYMERASE CHAIN REACTION; SKIN FIBROBLAST; UPREGULATION; ANIMAL; CELL COMMUNICATION; CULTURE MEDIUM; FIBROBLAST; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN TUMOR; STROMA CELL;

ANIMALS; CELL COMMUNICATION; COCULTURE TECHNIQUES; CULTURE MEDIA, CONDITIONED; CYTOKINES; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MELANOMA; NEOPLASM INVASIVENESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN NEOPLASMS; STROMAL CELLS; UP-REGULATION;

EID: 70349252148     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24463     Document Type: Article

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