Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 24, 2010, Pages 11026-11031

  Grugan, Katharine D ^a,b   Miller, Charles G ^a,b   Yao, Yao ^a,b   Michaylira, Carmen Z ^a,b   Ohashi, Shinya ^a,b   Klein Szanto, Andres J ^c   Diehl, J Alan ^b   Herlyn, Meenhard ^d   Han, May ^e   Nakagawa, Hiroshi ^a,b   Rustgi, Anil K ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c FOX CHASE CANCER CENTER   (United States)

^d WISTAR INSTITUTE   (United States)

^e AVEO ONCOLOGY   (United States)

Author keywords

C met; Cancer associated fibroblasts; Esophageal cancer; Organotypic culture; Tumor microenvironment

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN P53; SCATTER FACTOR; SCATTER FACTOR RECEPTOR;

ARTICLE; CANCER GROWTH; CANCER INVASION; CELL INVASION; CONTROLLED STUDY; DNA MODIFICATION; EPITHELIUM CELL; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; ESOPHAGUS MUCOSA; FETUS; FIBROBLAST; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR GROWTH;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TRANSFORMED; EPITHELIAL CELLS; ESOPHAGEAL NEOPLASMS; EXTRACELLULAR MATRIX; FEMALE; FIBROBLASTS; GENE EXPRESSION; GENES, P53; HEPATOCYTE GROWTH FACTOR; HUMANS; MALE; MUTATION; NEOPLASM INVASIVENESS; PROTO-ONCOGENE PROTEINS C-MET; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

EID: 77954635026     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914295107     Document Type: Article

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