-
1
-
-
12944271053
-
Cancer statistics
-
Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin 2005;55:10-30.
-
(2005)
CA Cancer J Clin
, vol.2005
, Issue.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
-
2
-
-
0029741643
-
Recurrence of hepato-cellular carcinoma after surgery
-
Yamamoto J, Kosuge T, Takayama T, et al. Recurrence of hepato-cellular carcinoma after surgery. Br J Surg 1996;83:1219-22.
-
(1996)
Br J Surg
, vol.83
, pp. 1219-1222
-
-
Yamamoto, J.1
Kosuge, T.2
Takayama, T.3
-
3
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
Wilhelm SM, Carter C, Tang L, et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 2004;64:7099-109.
-
(2004)
Cancer Res
, vol.64
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
-
4
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
SHARP Investigators Study Group
-
Llovet JM, Ricci S, Mazzaferro V, et al.; SHARP Investigators Study Group. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008;359:378-90.
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
-
5
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
Cheng AL, Kang YK, Chen Z,, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 2009;10:25-34.
-
(2009)
Lancet Oncol
, vol.10
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
-
6
-
-
34249289041
-
Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?Nat Rev Cancer 2007;7:415-28.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
7
-
-
34848826864
-
Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression
-
Hugo H, Ackland ML, Blick T, et al. Epithelial-mesenchymal and mesenchymal-epithelial transitions in carcinoma progression. J Cell Physiol 2007;213:374-83.
-
(2007)
J Cell Physiol
, vol.213
, pp. 374-383
-
-
Hugo, H.1
Ackland, M.L.2
Blick, T.3
-
8
-
-
70349729970
-
Epithelial-mesenchymal transition and cell cooperativity in metastasis
-
Tsuji T, Ibaragi S, Hu GF. Epithelial-mesenchymal transition and cell cooperativity in metastasis. Cancer Res 2009;69:7135-9.
-
(2009)
Cancer Res
, vol.69
, pp. 7135-7139
-
-
Tsuji, T.1
Ibaragi, S.2
Hu, G.F.3
-
11
-
-
33846566813
-
Effect of hepatocyte growth factor on methionine adenosyltransferase genes and growth is cell density-dependent in HepG2 cells
-
Yang H, Magilnick N, Noureddin M, Mato JM, Lu SC. Effect of hepatocyte growth factor on methionine adenosyltransferase genes and growth is cell density-dependent in HepG2 cells. J Cell Physiol 2007;210:766-73.
-
(2007)
J Cell Physiol
, vol.210
, pp. 766-773
-
-
Yang, H.1
Magilnick, N.2
Noureddin, M.3
Mato, J.M.4
Lu, S.C.5
-
12
-
-
59149098933
-
Prognostic impact of surgical complications and preoperative serum hepatocyte growth factor in hepatocellular carcinoma patients after initial hepatectomy
-
Mizuguchi T, Nagayama M, Meguro M, et al. Prognostic impact of surgical complications and preoperative serum hepatocyte growth factor in hepatocellular carcinoma patients after initial hepatectomy. J Gastrointest Surg 2009;13:325-33.
-
(2009)
J Gastrointest Surg
, vol.13
, pp. 325-333
-
-
Mizuguchi, T.1
Nagayama, M.2
Meguro, M.3
-
13
-
-
40049092502
-
Significance of serum hepatocyte growth factor levels in patients with hepatocellular carcinoma undergoing hepatic resection
-
Chau GY, Lui WY, Chi CW, et al. Significance of serum hepatocyte growth factor levels in patients with hepatocellular carcinoma undergoing hepatic resection. Eur J Surg Oncol 2008;34:333-8.
-
(2008)
Eur J Surg Oncol
, vol.34
, pp. 333-338
-
-
Chau, G.Y.1
Lui, W.Y.2
Chi, C.W.3
-
14
-
-
0037103090
-
Serum concentrations of human hepatocyte growth factor is a useful indicator for predicting the occurrence of hepatocellular carcinomas in C-viral chronic liver diseases
-
Yamagamim H, Moriyama M, Matsumura H, et al. Serum concentrations of human hepatocyte growth factor is a useful indicator for predicting the occurrence of hepatocellular carcinomas in C-viral chronic liver diseases. Cancer 2002;95:824-34.
-
(2002)
Cancer
, vol.95
, pp. 824-834
-
-
Yamagamim, H.1
Moriyama, M.2
Matsumura, H.3
-
15
-
-
58749111083
-
SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion
-
Tanaka K, Arao T, Maegawa M, et al. SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion. Int J Cancer 2009;124:1072-80.
-
(2009)
Int J Cancer
, vol.124
, pp. 1072-1080
-
-
Tanaka, K.1
Arao, T.2
Maegawa, M.3
-
16
-
-
70349754442
-
mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells
-
Matsumoto K, Arao T, Tanaka K, et al. mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells. Cancer Res 2009;69:7160-4.
-
(2009)
Cancer Res
, vol.69
, pp. 7160-7164
-
-
Matsumoto, K.1
Arao, T.2
Tanaka, K.3
-
17
-
-
77950219816
-
FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth
-
Kaneda H, Arao T, Tanaka K, et al. FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth. Cancer Res 2010;70:2053-63.
-
(2010)
Cancer Res
, vol.70
, pp. 2053-2063
-
-
Kaneda, H.1
Arao, T.2
Tanaka, K.3
-
18
-
-
33645302628
-
The epithelial-mesenchymal transition: New insights in signaling, development, and disease
-
Lee JM, Dedhar S, Kalluri R, Thompson EW: The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 2006;172:973-81.
-
(2006)
J Cell Biol
, vol.172
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
19
-
-
42549107446
-
Cadherin switching
-
Wheelock MJ, Shintani Y, Maeda M, Fukumoto Y, Johnson KR. Cadherin switching. J Cell Sci 2008;121:727-35.
-
(2008)
J Cell Sci
, vol.121
, pp. 727-735
-
-
Wheelock, M.J.1
Shintani, Y.2
Maeda, M.3
Fukumoto, Y.4
Johnson, K.R.5
-
20
-
-
35148832569
-
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression
-
Lo HW, Hsu SC, Xia W, et al. Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression. Cancer Res 2007;67:9066-76.
-
(2007)
Cancer Res
, vol.67
, pp. 9066-9076
-
-
Lo, H.W.1
Hsu, S.C.2
Xia, W.3
-
21
-
-
68249092353
-
A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelialmesenchymal transition
-
Vincent T, Neve EP, Johnson JR, et al. A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelialmesenchymal transition. Nat Cell Biol 2009;11:943-50.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 943-950
-
-
Vincent, T.1
Neve, E.P.2
Johnson, J.R.3
-
22
-
-
27844461512
-
Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 3' kinase/AKT pathways
-
Larue L, Bellacosa A. Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathways. Oncogene 2005;24:7443-54.
-
(2005)
Oncogene
, vol.24
, pp. 7443-7454
-
-
Larue, L.1
Bellacosa, A.2
-
23
-
-
24644487312
-
TGF-beta and epithelial-to-mesenchymal transitions
-
Zavadil J, Böttinger EP. TGF-beta and epithelial-to-mesenchymal transitions. Oncogene 2005;24:5764-74.
-
(2005)
Oncogene
, vol.24
, pp. 5764-5774
-
-
Zavadil, J.1
Böttinger, E.P.2
-
24
-
-
33846212284
-
Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
-
Liu L, Cao Y, Chen C, et al. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res 2006;66:11851-8.
-
(2006)
Cancer Res
, vol.66
, pp. 11851-11858
-
-
Liu, L.1
Cao, Y.2
Chen, C.3
-
25
-
-
70349165716
-
Epithelial-mesenchymal transition in cancer metastasis: Mechanisms, markers and strategies to overcome drug resistance in the clinic
-
Voulgari A, Pintzas A. Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. Biochim Biophys Acta 2009;1796:75-90.
-
(2009)
Biochim Biophys Acta
, vol.1796
, pp. 75-90
-
-
Voulgari, A.1
Pintzas, A.2
-
26
-
-
29344465338
-
Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients
-
Yauch RL, Januario T, Eberhard DA, et al. Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients. Clin Cancer Res 2005; 11:8686-98.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8686-8698
-
-
Yauch, R.L.1
Januario, T.2
Eberhard, D.A.3
-
27
-
-
57049132745
-
Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy
-
Thomson S, Petti F, Sujka-Kwok I, Epstein D, Haley JD. Kinase switching in mesenchymal-like non-small cell lung cancer lines contributes to EGFR inhibitor resistance through pathway redundancy. Clin Exp Metastasis 2008;25:843-54.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 843-854
-
-
Thomson, S.1
Petti, F.2
Sujka-Kwok, I.3
Epstein, D.4
Haley, J.D.5
-
28
-
-
42049116522
-
Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells
-
Fuchs BC, Fujii T, Dorfman JD, et al. Epithelial-to-mesenchymal transition and integrin-linked kinase mediate sensitivity to epidermal growth factor receptor inhibition in human hepatoma cells. Cancer Res 2008;68:2391-9.
-
(2008)
Cancer Res
, vol.68
, pp. 2391-2399
-
-
Fuchs, B.C.1
Fujii, T.2
Dorfman, J.D.3
-
29
-
-
67650999217
-
Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer
-
Arumugam T, Ramachandran V, Fournier KF, et al. Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer. Cancer Res 2009;69:5820-8.
-
(2009)
Cancer Res
, vol.69
, pp. 5820-5828
-
-
Arumugam, T.1
Ramachandran, V.2
Fournier, K.F.3
-
30
-
-
65549141305
-
Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway
-
Wang Z, Li Y, Kong D, et al. Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine-resistant pancreatic cancer cells is linked with activation of the notch signaling pathway. Cancer Res 2009;69:2400-7.
-
(2009)
Cancer Res
, vol.69
, pp. 2400-2407
-
-
Wang, Z.1
Li, Y.2
Kong, D.3
-
31
-
-
60649089997
-
Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells
-
Kudo-Saito C, Shirako H, Takeuchi T, Kawakami Y. Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells. Cancer Cell 2009;15:195-206.
-
(2009)
Cancer Cell
, vol.15
, pp. 195-206
-
-
Kudo-Saito, C.1
Shirako, H.2
Takeuchi, T.3
Kawakami, Y.4
-
32
-
-
67649200336
-
E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/ HDAC2 repressor complex
-
von Burstin J, Eser S, Paul MC, et al. E-cadherin regulates metastasis of pancreatic cancer in vivo and is suppressed by a SNAIL/HDAC1/ HDAC2 repressor complex. Gastroenterology 2009;137:361-71.
-
(2009)
Gastroenterology
, vol.137
, pp. 361-371
-
-
Von Burstin, J.1
Eser, S.2
Paul, M.C.3
-
33
-
-
72949120827
-
Comprehensive analysis of the independent effect of Twist and Snail in promoting metastasis of hepatocellular carcinoma
-
Yang MH, Chen CL, Chau GY, et al. Comprehensive analysis of the independent effect of Twist and Snail in promoting metastasis of hepatocellular carcinoma. Hepatology 2009;50:1464-74.
-
(2009)
Hepatology
, vol.50
, pp. 1464-1474
-
-
Yang, M.H.1
Chen, C.L.2
Chau, G.Y.3
|